LOCUS       DARYMD010000001        84004 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYMD010000001 DARYMD010000000
VERSION     DARYMD010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84004
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..376
                     /locus_tag="TU818_000001"
     CDS             <1..376
                     /locus_tag="TU818_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL0922876.1"
                     /translation="QGGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTK
                     NHLFMTHIDSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGA
                     VLTGYSLTRGRLSRQKHKRHHE"
     gene            692..933
                     /locus_tag="TU818_000002"
                     /pseudo
     CDS             692..933
                     /locus_tag="TU818_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
     gene            936..2093
                     /gene="essB"
                     /locus_tag="TU818_000003"
     CDS             936..2093
                     /gene="essB"
                     /locus_tag="TU818_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL0922877.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYTLLASEHSLFVPSKLEQAF
                     DKLILEASIDDMYDWSALEAMIVEEKLRHLLNLSELFDQLLDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMGGKLPFYKGN
                     LFCEAVAKAEALQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPKEEKAAGSSSDKE"
     gene            2105..6481
                     /gene="essC"
                     /locus_tag="TU818_000004"
     CDS             2105..6481
                     /gene="essC"
                     /locus_tag="TU818_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL0922878.1"
                     /translation="MTYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEESYSTGKHCVALSDEVTVTLLILEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVSYYLNGKWTKGKQPLKASDELVFSDGLVLSFQDQLLSIQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFHIDYSDSELTKHHEKAKQRVQELIAYYQVTAQVPIQNAIASPIGYIGA
                     RKVVIEQVQQLMMQIATFHSYHDVQFIPIFREEELPLWNWSRWLPHTKLKVLNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEVFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITANGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PERQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRAVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREDVVPA
                     GFTFKKSILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPGQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            6494..6823
                     /locus_tag="TU818_000005"
     CDS             6494..6823
                     /locus_tag="TU818_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL0922879.1"
                     /translation="MSTVTMLPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            6827..7261
                     /locus_tag="TU818_000006"
     CDS             6827..7261
                     /locus_tag="TU818_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL0922880.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            7263..7547
                     /locus_tag="TU818_000007"
     CDS             7263..7547
                     /locus_tag="TU818_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL0922881.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQSEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
     gene            complement(7618..8920)
                     /locus_tag="TU818_000008"
                     /pseudo
     CDS             complement(7618..8920)
                     /locus_tag="TU818_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9301..10011
                     /gene="ccdA2"
                     /locus_tag="TU818_000009"
     CDS             9301..10011
                     /gene="ccdA2"
                     /locus_tag="TU818_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL0922882.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFIILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVI
                     MGLLLMTGNLNSLSGLFE"
     gene            10025..10675
                     /locus_tag="TU818_000010"
     CDS             10025..10675
                     /locus_tag="TU818_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEL0922883.1"
                     /translation="MKKTTFLTTGLACLALLTACSAKDKMAMNDSKKDHMTRTDDKSK
                     MKKDQKDKMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK"
     gene            10693..11805
                     /gene="msrB"
                     /locus_tag="TU818_000011"
     CDS             10693..11805
                     /gene="msrB"
                     /locus_tag="TU818_000011"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL0922884.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGIYYTDPS
                     DLTTIDMVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            12073..12813
                     /locus_tag="TU818_000012"
     CDS             12073..12813
                     /locus_tag="TU818_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL0922885.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            12810..14528
                     /locus_tag="TU818_000013"
     CDS             12810..14528
                     /locus_tag="TU818_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0922886.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDLRSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRRGFAFIVNDKHEFVY
                     HSKNTVYSSEREMAAMKPYLAVADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMISVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVLEADRHVILSVWDNGK
                     GISLADDSSQALLECGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            14567..15655
                     /locus_tag="TU818_000014"
     CDS             14567..15655
                     /locus_tag="TU818_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL0922887.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            15670..16374
                     /locus_tag="TU818_000015"
     CDS             15670..16374
                     /locus_tag="TU818_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL0922888.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNTASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            16634..17122
                     /locus_tag="TU818_000016"
     CDS             16634..17122
                     /locus_tag="TU818_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL0922889.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLIIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(17632..18105)
                     /locus_tag="TU818_000017"
     CDS             complement(17632..18105)
                     /locus_tag="TU818_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL0922890.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            18246..18926
                     /locus_tag="TU818_000018"
     CDS             18246..18926
                     /locus_tag="TU818_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL0922891.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     NYFLQYTT"
     gene            19195..20430
                     /gene="arcA"
                     /locus_tag="TU818_000019"
     CDS             19195..20430
                     /gene="arcA"
                     /locus_tag="TU818_000019"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL0922892.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEELRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            20440..20871
                     /locus_tag="TU818_000020"
     CDS             20440..20871
                     /locus_tag="TU818_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0922893.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSEISAQSFYEGLGYQAFGEPYDEDGEPCQSVEKYL"
     gene            20886..21899
                     /gene="argF"
                     /locus_tag="TU818_000021"
     CDS             20886..21899
                     /gene="argF"
                     /locus_tag="TU818_000021"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL0922894.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKAANDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            22061..23554
                     /locus_tag="TU818_000022"
     CDS             22061..23554
                     /locus_tag="TU818_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL0922895.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLRVVNKTGA
                     LDTGIASVVRKNKGREKLLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFDIQLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAVVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     VFVVLAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            23571..24902
                     /locus_tag="TU818_000023"
     CDS             23571..24902
                     /locus_tag="TU818_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL0922896.1"
                     /translation="METYIQPRHQEACVAAIKKIVSYPSVLNEGENDTPFGQAIQDVL
                     EATLALCQDLGFNTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHKDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSPKLNLEVGQAYNVVPARASYQG
                     DKLEALKEELDRLGFEYVVKDDELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEMTEIRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYRKKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            24920..25870
                     /gene="arcC"
                     /locus_tag="TU818_000024"
     CDS             24920..25870
                     /gene="arcC"
                     /locus_tag="TU818_000024"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL0922897.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKSNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            26090..27082
                     /locus_tag="TU818_000025"
                     /pseudo
     CDS             26090..27082
                     /locus_tag="TU818_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
     gene            27254..27793
                     /gene="rsmD"
                     /locus_tag="TU818_000026"
     CDS             27254..27793
                     /gene="rsmD"
                     /locus_tag="TU818_000026"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL0922898.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIKLTKASQQFTLLKMNAER
                     ALDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDDVMIVCETDRSVALPEAIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            27783..28283
                     /gene="coaD"
                     /locus_tag="TU818_000027"
     CDS             27783..28283
                     /gene="coaD"
                     /locus_tag="TU818_000027"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL0922899.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLSEAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMATHDLQPVSSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKN"
     gene            28261..29298
                     /locus_tag="TU818_000028"
     CDS             28261..29298
                     /locus_tag="TU818_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL0922900.1"
                     /translation="MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TVQDAISYLKK"
     gene            29860..30474
                     /locus_tag="TU818_000029"
     CDS             29860..30474
                     /locus_tag="TU818_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL0922901.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            30478..31560
                     /gene="rlmN"
                     /locus_tag="TU818_000030"
     CDS             30478..31560
                     /gene="rlmN"
                     /locus_tag="TU818_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL0922902.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFVAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDKRAQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            32842..33372
                     /locus_tag="TU818_000031"
     CDS             32842..33372
                     /locus_tag="TU818_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL0922903.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            33745..33978
                     /locus_tag="TU818_000032"
     CDS             33745..33978
                     /locus_tag="TU818_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL0922904.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            33953..34924
                     /locus_tag="TU818_000033"
     CDS             33953..34924
                     /locus_tag="TU818_000033"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL0922905.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSSIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            34934..35314
                     /locus_tag="TU818_000034"
     CDS             34934..35314
                     /locus_tag="TU818_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL0922906.1"
                     /translation="MSPLTMIGWVLLAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPAQQFTTSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            35710..37551
                     /gene="typA"
                     /locus_tag="TU818_000035"
     CDS             35710..37551
                     /gene="typA"
                     /locus_tag="TU818_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL0922907.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLVELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            37633..37887
                     /locus_tag="TU818_000036"
     CDS             37633..37887
                     /locus_tag="TU818_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL0922908.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            38033..39394
                     /locus_tag="TU818_000037"
     CDS             38033..39394
                     /locus_tag="TU818_000037"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL0922909.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGNHSALLAGNIGFPASEVAQAATA
                     KDILVMELSSFQLLGTEQFQPHIAVITNLVPTHLDYHGSFEDYIAAKWRIQHRMTDKD
                     YLVLNADQELVKSLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISRTLSHFRGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMILLGESAERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKAGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EAQ"
     gene            39391..40473
                     /locus_tag="TU818_000038"
     CDS             39391..40473
                     /locus_tag="TU818_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL0922910.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDKGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDIFKVGFGVMQSLFIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLAKLKHVG
                     AVTKVTGPGSRSVTSKQLEAVLEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSWHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMK
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            40474..41664
                     /locus_tag="TU818_000039"
     CDS             40474..41664
                     /locus_tag="TU818_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL0922911.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGEAASKADQEDTDEAEEKTEVSQAGTDEGEPLPEASEQEVPSPKDKPLKVP
                     KEKSPKQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDSG
                     IKSSDYWITLLASPGSYENAVLKANPWVKKVALRYGFPNHFRFDVTEFDIIAYAQVAE
                     GFQLILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVSS
                     ANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTTA
                     EIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTEQ
                     ANQQ"
     gene            41876..43240
                     /gene="ftsA"
                     /locus_tag="TU818_000040"
     CDS             41876..43240
                     /gene="ftsA"
                     /locus_tag="TU818_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL0922912.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            43264..44592
                     /gene="ftsZ"
                     /locus_tag="TU818_000041"
     CDS             43264..44592
                     /gene="ftsZ"
                     /locus_tag="TU818_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL0922913.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRRSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            44595..45266
                     /locus_tag="TU818_000042"
     CDS             44595..45266
                     /locus_tag="TU818_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL0922914.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            45279..45941
                     /locus_tag="TU818_000043"
     CDS             45279..45941
                     /locus_tag="TU818_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL0922915.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            45946..46203
                     /locus_tag="TU818_000044"
     CDS             45946..46203
                     /locus_tag="TU818_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL0922916.1"
                     /translation="MIFILLILLKLIKVYSYLLLVYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLIS"
     gene            46200..46994
                     /locus_tag="TU818_000045"
     CDS             46200..46994
                     /locus_tag="TU818_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL0922917.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIAKARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            47004..47759
                     /locus_tag="TU818_000046"
     CDS             47004..47759
                     /locus_tag="TU818_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL0922918.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            48030..50828
                     /locus_tag="TU818_000047"
     CDS             48030..50828
                     /locus_tag="TU818_000047"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL0922919.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GILDTDTYVVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYGKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQEILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQEHGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINTAYERYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDTILE
                     EWEAFMTLRAQAQKALEEARHDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSAAN"
     gene            complement(51306..51608)
                     /locus_tag="TU818_000048"
     CDS             complement(51306..51608)
                     /locus_tag="TU818_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL0922920.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(51670..52119)
                     /locus_tag="TU818_000049"
     CDS             complement(51670..52119)
                     /locus_tag="TU818_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0922921.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIEAGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFLPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(52279..54531)
                     /locus_tag="TU818_000050"
     CDS             complement(52279..54531)
                     /locus_tag="TU818_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL0922922.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGHNGGGHNGYRPNH
                     TQPAQEANKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
                     PGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEE
                     IRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIE
                     KDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQSAIEAAANLSNRYIQ
                     DRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFR
                     DQIAKYKEMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLK
                     KHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGS
                     ADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKAH
                     PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNS
                     VLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQK
                     VKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDMRAVLTSNGHIIIKP
                     VVKSQAKQAD"
     gene            54813..55043
                     /locus_tag="TU818_000051"
     CDS             54813..55043
                     /locus_tag="TU818_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL0922923.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(55525..56463)
                     /locus_tag="TU818_000052"
     CDS             complement(55525..56463)
                     /locus_tag="TU818_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0922924.1"
                     /translation="MKKTIRKYSVCSAAIALATMASLGTAGNARAEDYTRLESYPDPA
                     ELIRDGLGDGEVRVYLHTLRQFMQTYLQNLELQAKKGGPQGPVGPAGPRGERGEQGPV
                     GPMGPRGDKGETGETGPKGEQGPAGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG
                     QRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQKPKGDQGKDTKPSAPKAPEKTPAPKAPEKSAQPKAPAPKSAPAAQ
                     KSTLPATGETNHPFFTLAALSVITSAGVLNLKKKKS"
     gene            56805..57488
                     /locus_tag="TU818_000053"
     CDS             56805..57488
                     /locus_tag="TU818_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0922925.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTMMISACVVFFGTIIGLLVTLIKRS
                     HIKPLSWLVSLYVWIFRGTPMVVQIMIAFAWLHFNDLPIVGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            57490..58227
                     /locus_tag="TU818_000054"
     CDS             57490..58227
                     /locus_tag="TU818_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0922926.1"
                     /translation="MTETVISIRQLHKSFGKHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPVQVFEAPKEERTKDFLSKVLS"
     gene            58671..60365
                     /locus_tag="TU818_000055"
     CDS             58671..60365
                     /locus_tag="TU818_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL0922927.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAVHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGAAILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYDVETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNEPIEHAGAMSLKTIVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            60477..61331
                     /locus_tag="TU818_000056"
     CDS             60477..61331
                     /locus_tag="TU818_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL0922928.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            61328..62182
                     /locus_tag="TU818_000057"
     CDS             61328..62182
                     /locus_tag="TU818_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL0922929.1"
                     /translation="MIIDQSFVARVVVPRQADSHKGSYGRVLLVGGLYPYGGAIIMVA
                     LACVHSGAGLVTVATDRETIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKRAADVKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQYDAANQAALKHFPRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVAKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            62466..63806
                     /locus_tag="TU818_000058"
     CDS             62466..63806
                     /locus_tag="TU818_000058"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL0922930.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSMIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGIVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANITKANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDIVSWIAEQQS
                     RSYQACLRYIRQGQERVDKLSYSVIFRQPERLYDAYSQRLDRLTTSLMTTFKETLSGA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGVVAACVKDIKKGDHLSIIMRDGQLEVEVEDVNEKNI"
     gene            63784..63999
                     /locus_tag="TU818_000059"
     CDS             63784..63999
                     /locus_tag="TU818_000059"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL0922931.1"
                     /translation="MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            63999..64868
                     /locus_tag="TU818_000060"
     CDS             63999..64868
                     /locus_tag="TU818_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL0922932.1"
                     /translation="MDKLTRINATIHQYYDRQSTVSADLEEAILYSVDGGGKRLRPLM
                     LLELLEGFGLALTDAHYAVAAAVEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFNEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLIQQFSLASGTFGMVGGQLLDMKGEHQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDL
                     TASFADLGKTPQKDLAAAKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            64861..65688
                     /locus_tag="TU818_000061"
     CDS             64861..65688
                     /locus_tag="TU818_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL0922933.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPTLHCILQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVADTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKGKGSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            65675..66145
                     /locus_tag="TU818_000062"
     CDS             65675..66145
                     /locus_tag="TU818_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL0922934.1"
                     /translation="MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYVYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            66163..67824
                     /gene="recN"
                     /locus_tag="TU818_000063"
     CDS             66163..67824
                     /gene="recN"
                     /locus_tag="TU818_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL0922935.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIEAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGDDRSSDELERELKVLEKQLVMTASQLSDKRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGSYGQVLAISHLPQVVAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            68045..68917
                     /locus_tag="TU818_000064"
     CDS             68045..68917
                     /locus_tag="TU818_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0922936.1"
                     /translation="MLKKRMGLASLLVLMTFVYQCCSVTAEQYSDTEVEVLQISEEKS
                     QIMENQEALKDLTTSSDQLKKEALKPKEAATNKSKQEASTVYLAEDDPVTIDSSDEES
                     NQDIIADSVPDLVIKGDQVDVSEVMVSVKEDSSKVAKQRTDAAQRYSIAKHQLTQKLE
                     AFNAATDQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLGS
                     SVTILDELGRVISDISGHKGMLPFNRKISFKVHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANKKS"
     gene            69055..69906
                     /locus_tag="TU818_000065"
     CDS             69055..69906
                     /locus_tag="TU818_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0922937.1"
                     /translation="MELKMGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSD
                     NELKEEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTI
                     EASRQGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQAGASLEEILEAVEDIKRKTE
                     LYIGVSALEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLD
                     SYLAENSQRQIAEVAISYAGQRDFADSLKKTIATVFDGPITVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            69899..70741
                     /locus_tag="TU818_000066"
     CDS             69899..70741
                     /locus_tag="TU818_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL0922938.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSSFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNKKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            70719..71306
                     /locus_tag="TU818_000067"
     CDS             70719..71306
                     /locus_tag="TU818_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL0922939.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNAAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTEKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            71404..71679
                     /locus_tag="TU818_000068"
     CDS             71404..71679
                     /locus_tag="TU818_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL0922940.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(71740..72444)
                     /locus_tag="TU818_000069"
     CDS             complement(71740..72444)
                     /locus_tag="TU818_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL0922941.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTYASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTFDPQILSAIKPGTHYTKQG
                     FMSTTAIKNAAMPHRSVELRIQVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
     gene            complement(72755..73963)
                     /locus_tag="TU818_000070"
     CDS             complement(72755..73963)
                     /locus_tag="TU818_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0922942.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYSNSSGIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISYAFSGTAFRAYVVTLVETERLVHFNAQLEIVSQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASLLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGMLLITAMALLKLPVIVIALGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMATASLAYYCNY
                     RQSSKKKPFI"
     gene            complement(74018..74911)
                     /locus_tag="TU818_000071"
     CDS             complement(74018..74911)
                     /locus_tag="TU818_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0922943.1"
                     /translation="MTNHQLGKAFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCNPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLSGIKDMTTAISIFESLDCPHLA
                     HNYQKDFERFVASSSLICKKT"
     gene            75280..75453
                     /locus_tag="TU818_000072"
     CDS             75280..75453
                     /locus_tag="TU818_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0922944.1"
                     /translation="MPIIVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            complement(75498..76433)
                     /locus_tag="TU818_000073"
     CDS             complement(75498..76433)
                     /locus_tag="TU818_000073"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL0922945.1"
                     /translation="MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVV
                     GMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQE
                     GPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP"
     gene            76676..77371
                     /locus_tag="TU818_000074"
     CDS             76676..77371
                     /locus_tag="TU818_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL0922946.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            77480..78001
                     /locus_tag="TU818_000075"
     CDS             77480..78001
                     /locus_tag="TU818_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL0922947.1"
                     /translation="MKVKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSNALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASKAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            78396..78935
                     /locus_tag="TU818_000076"
     CDS             78396..78935
                     /locus_tag="TU818_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0922948.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            79074..79844
                     /locus_tag="TU818_000077"
     CDS             79074..79844
                     /locus_tag="TU818_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL0922949.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLAKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKAKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWIDFATNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            79956..82010
                     /locus_tag="TU818_000078"
     CDS             79956..82010
                     /locus_tag="TU818_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL0922950.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELKVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHEIREIKTSRSGEVISDKIVEKGQMGRNLKLSVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            82022..82618
                     /gene="recR"
                     /locus_tag="TU818_000079"
     CDS             82022..82618
                     /gene="recR"
                     /locus_tag="TU818_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL0922951.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRLL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            82766..83812
                     /locus_tag="TU818_000080"
     CDS             82766..83812
                     /locus_tag="TU818_000080"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL0922952.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
BASE COUNT        23629 a        15812 c        20144 g        24419 t
ORIGIN      
        1 tcaggggggt gagaaaaaag acattagcta catcgagcaa gagggcgatc tgtctgccct
       61 atttcaatca gagacagact taagcattaa aaagaaacag cagcatcgaa aagaaactag
      121 tcagacgacc aagaatcacc tatttatgac tcatattgat agtgacaacc ttgttgcaag
      181 gtatcagcca ctcttattta acccagagca gcgtctggca gcaacagatg accagtatgg
      241 tgttttgctc gctcaaaaaa ctatcggcat cacttggcaa atgctggcca tacttcttgt
      301 gggagctgta ctgactggct attctctgac tagagggcga ttatcaaggc aaaaacacaa
      361 aagacatcac gagtagaatc gtctgtcaag agtatctact cactgaaaat agagggctag
      421 cttaggagac ttcctaatgc tgcatttata agaaaaggct ctcagctgtt ttgacagtat
      481 tgggcaaggc cttagggcct gtagcaaata tgaagagcag ctttgatcag caggtagcaa
      541 gtcagtcaat acaaatgctt gaaagcctac ctgctaagaa aagtgtgtgt tctacgatac
      601 tttagtgatg tgaatcacct caagaggctt tagctagctt ggcaggtgat gtcaggtgac
      661 atggaaactt atcaggaaag ggctaatttt tatggagaat tatattagta tcagtcttga
      721 ttgctcgcat ttttttcaca ggaatttgat ttgcgggtac caaggacaat gacctttaag
      781 gagctattac aaatcgtatc agatgcttat ggtttgggat ttcaggtggt aaatcccagt
      841 gctagaaatg agcaaggtgg tcagctgatg acaagcacca gtcgcatgga taccctaaaa
      901 aatggtgcac tgttagtatt ggaaaattta taaacatgga gaaaaagatg aaaacaataa
      961 tacgtgagct attggttgag gatgttaaag gagatgctga ggttgcttat accttactag
     1021 cttctgagca ttctcttttt gttccttcca agttagaaca ggctttcgac aagctgattc
     1081 tagaggctag cattgatgac atgtatgact ggtcagccct agaggcgatg attgttgagg
     1141 aaaagctaag gcatttgcta aatcttagtg agctgtttga tcagctcttg gactcaaagt
     1201 tcacctacag ctttacacca gataatctgg tctttaaccg taatgcagag ccacagttga
     1261 tttttcgggg aatcaaggat caggttcctc cttaccagcc gcttgagcgt gaggtctttg
     1321 tgaatacact gaaatgtatg acaattgcct tgcttgataa aaagaccagc tatgacgctc
     1381 tgatgggtgg caagcttccc ttttacaaag gcaatctttt ttgcgaagca gtggccaagg
     1441 ctgaggcgct gcaggagttg caggagcttt tagcgacaaa gtaccatgag gagcaaaaag
     1501 acaataaaga gcatttttct cgtgttgcta acaagacgat atcgcgcttg aaattgacca
     1561 ccatttgttc atcagtgctt gctttgttgt ctttggcggg cgttctttat tttctattgt
     1621 ttgctatgcc ttatcaggaa atggttgcta gtctgcgtat ggcttttatt aatcaagact
     1681 attctaaggt tatcacaaca gcgaagcata cagacagtaa ggccttaagc cagggtgata
     1741 aatatattgt ggcttactct gtcataatga cagagcctct aacagacaag caaaaggagg
     1801 aattaagtaa aatatcgaac cagtctaatg aagattattt acgctattgg gtgctgattg
     1861 gtcaagcaag gatagatgat gccatggata ttgcgagcta tctagacgac ccgcagctct
     1921 tgatgtatgg cttgactaag aagattgatg atgttcagcg agatcctaat ctgacagcag
     1981 aggcgcgtac agagcagctt aacagctata agagcaaatt agacgagctc aaaaaggcct
     2041 acctgacgcc taaagaggaa aaagcagcag gctctagcag tgacaaggag tgacggagga
     2101 atttatgaca taccttattt atgacgacaa tgcctatcac ctttattcgg ataccgttta
     2161 tcagttgggg ccttcatcag ggtctgatat tttcctgccc ttgctggagg atattacctt
     2221 atcagtggag ggatcaggtg ttgtcctact ggaagagagc tacagcactg gtaagcattg
     2281 tgttgctctt tctgatgagg ttacagtgac cttacttatt cttgaagctg tcactaaata
     2341 cctgctgcca gactcctcgc tttacatttc aggagagact accgcagcac ttcaattgct
     2401 tgattaccct agtgagctgg tgctgaccct agactctgat tctgccagct gctatagccc
     2461 ggtgtcttat tatctaaatg gtaaatggac gaaaggcaag cagcctctta aagcatctga
     2521 tgaacttgtt ttttcagatg gcttagtgct tagttttcag gatcagctgc tatcgattca
     2581 gtccttgtat gctattcaga cagcattgct gcctcttaca gaggcagtag ctgaggatag
     2641 agccagtgaa tttcatcgtt ctcctaggat tatcctgcgt gagcctgagg gaaaggtgac
     2701 gattgcttct gtacccacag atgatgaagg gaaaagacag tctttattaa agctgatcat
     2761 aacgcccctt gcgatgattg tctttacagg gctctcttat gtctttttcc gaggtggggg
     2821 aatgctcatg atgatgatgg gaatgtctgt gattacgatt ggaagctcca ttcattctta
     2881 tttttcagat aaaaaatggc ataaagaagc ccagcagcaa aaaatcaagg attatctagc
     2941 ctacttggat accaagtatg tggagctagc aggctatcgt gaggagcaaa tcgaagcact
     3001 gctgtatcat taccctaata tgacgactat tcttgaaatg gcacaaaaaa cagatcgccg
     3061 tatttatgag aaggctccat atcattttga ctttttgacc taccgcttgg ggctaggtga
     3121 tactccagcc agctttcaca ttgattattc agattctgag ctgaccaagc atcatgaaaa
     3181 ggcaaagcaa agggttcaag agctgattgc ttattatcag gtgacagcac aggtgcctat
     3241 ccaaaatgcg attgccagtc caatcggtta tattggagca cgcaaggtcg tgattgagca
     3301 ggttcagcag ctgatgatgc agatcgctac cttccatagc tatcatgatg tacagtttat
     3361 tcctattttt cgagaagaag agctgccatt gtggaattgg agccggtggc tgcctcatac
     3421 taagctaaag gtgctaaata gtcgtggctt tgtttatagt cagcgaacac gtgaccaatt
     3481 gttgacctcg ctttatcagc tgatcaagga gcggcaatta gacagtgagc aggataaggg
     3541 gacagaaaag caatacactc cgcattatat agtgctgatt actgacatga gcctcatgct
     3601 tgaccacaat atcatggaat acatcaatga ggatttgtct catctaggca ttcattatat
     3661 ttttgttgaa gaggtcattg aaagtctccc tgagcatgtc aaaacagtta ttgattatcg
     3721 tggagataag catgctcagc tcattttgca ggaggggctc tacctcaata aggcctttac
     3781 cccacttcaa cccttatcta tgaaggataa ggaggtcttt gctagacata tggcagggat
     3841 taatcacgtt gagaccttac gcaatgcgat tccaaatagt gtgacctttc ttgaaatgta
     3901 tggcgttaac aaggtcgagg agcttaatct cttaaagcgc tggaaggaaa atgaggctta
     3961 tcagacaatg gctgttccgc ttggggtgcg tggtcgtgat gacatcttgt acctaaacct
     4021 tcatgaaaaa gcccatggac cgcatggctt aattgcagga acgactggat ctggtaaatc
     4081 agagctggtt cagtcttata ttttgtcgct ggcggtgaat tatcacccct atgaggttgc
     4141 ctttttgctg attgactaca agggtggtgg tatggccaat ctctttgctg atttaccaca
     4201 tgtcgttgga accattacca acctagatgg caatcaggcc aatagggctt tggtatcgat
     4261 taaggcagag ctgaaaaagc gtcagcggat tttccttgaa aatgatgtca atcatattga
     4321 tcaatacact aagctattca aggaaggacg agttaaggag cccctcccac acctgttaat
     4381 catcagcgat gaatttgcag aattaaaggc caatcagcca gaatttatgg acgagctggt
     4441 ctcaaccgcc cgtattggtc gttctcttgg tgttaagctc attttagcaa cgcaaaagcc
     4501 aagtggtgtc gttaatgacc agatttggtc gaatgcgaag tttaaaattg ccttgaaggt
     4561 tcaagatgtt gcagattctc gtgaggtgat taaaacccca gatgcagcag agattactca
     4621 ggttggtcgt gcttatctcc aggttggaaa caatgaaatt tacgagctgt tccaaagtgc
     4681 ctggtctgga gcagactaca atccaaaagg acgacatacc attcagcatg agacaacggt
     4741 ctatgaaatc acagctaatg gtcaatacca agcgattaac aaggacctta gtggacttga
     4801 caagaagaga gaagcaaaat ccatgccaac agagctagat gcggttgtag cagaggctca
     4861 gcagctcttt gaggacctgc atattccaaa ggtggccagt ccttggctgc cgcccctttc
     4921 agaaaaaatc tatgccagtg atttacagtc cacgcatttc aaggactatt ggggacagac
     4981 acaggacttg cagcctgttt tgattggcta tcaggacatt cctgaacgcc aagagcagtc
     5041 cccactctat tttcatatgg aaaaggctgg gcatatcctc ttagtgtcta gtcctggctt
     5101 tgggaagtcc accttccttc aaggctttgc tttagatgtg atgcgaaagc aaacaccagc
     5161 acaggctcat ttttacctct atgattttgg gacaagtggc ttgattgcgc tttctgattt
     5221 tccacatgtg gcagattact ttaccctaga tgagacagac aagatcatga aatcacttcg
     5281 ttatttaagt gaagaaatca agacccgtaa gcatgcccta tctaaggcta aggcaaccaa
     5341 cctcaatcag tacaatcaat tatccaagga taccttcccg gctctttttg tcatcattga
     5401 tggctttgat agtgtcatgg acgcaccatt tgtagatgct gtctacaatg tcttaaacgt
     5461 tattgcgcgt gatggggctt ccttgggaat gtaccttgtt gtgaccttat caagacttaa
     5521 taccatgagg ctacagctgc agtctaactt taagaccaag ctatccctct tcttgtttga
     5581 taatagtgat ttatcaagtg tggttggtcg ctcaaatatc ccactagatg atatcaaggg
     5641 acgagctatc atgaaacgtg acgacattat ccaatttcag attgccttgc catatagcag
     5701 tgagtactat acagattata tggcggaggt aaaaagagag gtcgaggcga tgagggctgt
     5761 ttatcaaggt gctttgccag cggctattcc aatgctgcca gaaaaggtta caccggatat
     5821 gatagcagcc atgtcagact ctgctcagga ttttgtgatt ggtttggagc gagaggacgt
     5881 tgttcctgct ggctttacct ttaaaaagtc aatactgatg gcctctgata gcccagcctt
     5941 tgtggctaac tattataagc tgcttgattt tcagttgcag cgtctggctg accagtatcg
     6001 tacggttatt ttagatccta gtcagcgtat tgcaaggcaa ttctttgagg atagtcaacg
     6061 ctttagcaca gccttagatg ttggagacac tctaagggct attgtagagg actttaaaaa
     6121 gcgtcttgca gcacctggtc aggattatca aaaatggtta gttgtgattc ctgatattgc
     6181 agctacagcg ctggcagcag ggattagcga ggaagacttt aaacagcttg tgaccgaggg
     6241 cagccagtat ggggtcacgc ttatctttgt cggagcttat caggatctgg tcaataatac
     6301 ctatgataat tttgtgaagc ttgcaaatca gctcattgag caggtctttt taggcatgcg
     6361 gatcagtgac caaagccata cacgatatgc ttatatcagc aatgagcctt cacttagacc
     6421 gacccagggc tatatcctat acccagaagg ctatgacttt attcaattat tagagattta
     6481 gaaaggaaca aagatgtcaa cagttacgat gcttccactt ggtagtattg tcattttaaa
     6541 gggcaatact aagaaaatga tgattattgc gcgtgtgatc gcagctccaa tcaaagggga
     6601 ggtttaccgc tttgactatg gtgcctgcct gtatccggag ggcatgatgg gggatagttt
     6661 gatttacttt aatcatgacg atatttttaa gattattcaa gaaggctatg ctgatgatga
     6721 caatgctctg atgttagaga cgatagcaca ggctttagca acaacggaca ttccaaaagg
     6781 agatgtttca gccttaaacg atagaaagac tgttgaggac tagcttatgg ggcaagttga
     6841 ctacaatcat atcaatcagc ttcaacgtca ggttgaccag cacagggcca gtctatcaac
     6901 ggctacagca gagatagcgt caatagacga aaagctagag cgcttgcgtt gtgccaaggc
     6961 ttctgttgga gcgattcaag gagatgttca tcagatcaag gtctctgtga tggctaagag
     7021 ggatcagcct gattggaagg gagaacgcaa ggaccgcttg atgtcgagct gggaggagtt
     7081 ctctcatgac tatcgccact ttcagctgga gctagatgct tattacgatg ccatttgtga
     7141 tacgataaca cgcttggaga atcaaaaata tgagcagcaa gggcttatcg gctggtgtca
     7201 gagcatgatt aatagcttgg gaaatgagat tgaaaagcta tttcatatta gggagggcta
     7261 gcatgtttgg tgttattcaa ttatctgagg ttgtgtttgg ggcgcatgtg ttaagcctga
     7321 ctgctgctaa ggctagcttg tctgatgtca aagctagctt tcccagccat cagtcatcaa
     7381 gtaaggtgct agatctgtat cagtcagagt ttgaagcact ctctcagctt gttgctgcct
     7441 atgctaggct tttggaaaag gatattgcct tgattgccga ggctggtcaa gaattagccc
     7501 taacagataa gcagttggga caagctatag gatttaggtt acaataggag gagggtatgg
     7561 gatataagat tcactttgaa gccatcagtg ccgcccaaca aagcactcaa accacgatca
     7621 gtgcttgggg agaaaggtcg tcttctcttt tatgatgttc aaagcaaggt aaatactttt
     7681 cttgaagttg tcaacgtttc tgaatccaaa agcattgcgc ttgatacctt tgataaattt
     7741 gttagttgct tcaagcttgg cgttagaata aggcagttca atggcattga tgatatagtc
     7801 gttatagcgt ataaaggtgt ttaaagtcgt tttgaaggtg tgattgagat gaggcaaagc
     7861 atcttgactt aacccaaaga agagctctgt cttcttttct tgcaagtgaa aaagaagtca
     7921 ttggtacaga tcataatagc cttttaactc agggattcgt ttgaaaatct tattgagaca
     7981 ttgtctagga gttaatgttt ctctaaaggt cctagagtag aaagtattaa gagatagttt
     8041 ccagttatcc tttagactaa gcttccaata gtatttaaga gcccgatatt caagagcttt
     8101 cttatcaaat ggcttcatga gttgaatgcg agtttgattg agcgctctac tcatgtgcta
     8161 cacaatgtgg aagcgatcga gaacaatttt agcttttggg agtgaactag tccagtggac
     8221 taattcagcc tgagcttaaa aatagaagag cgaagggttt aatgagagga atgtaacttc
     8281 ctgacatatc gacagtaaca actttgccct tatttctagc ttctttggag tacttaaaga
     8341 agtgatttcg aatggttgtt tgacatctgt tattgcgaat gataatgatt ttcttggtgt
     8401 tgaaatcctg agcgataaag gctagtttgc ccttttgata agagaattcg ttccaggaaa
     8461 gcacctcagg taaggtggtg taatcctctt taaagtgaca ttgcttgagc ttatgataga
     8521 cggtagaggt agagatagcg agtttagcag caatatgcgt aaaagcttct ttattgagca
     8581 atagctgaga gatcttctgt ctaactggtt cagagatttg gcaatttttc ttcacgagat
     8641 tggtttcaga gacagctacc ttccgacagg tttgacattg aaacctgctc tttttcaatc
     8701 gaataaggct agggaagcca ccgatttcga tgaaagggat tttagagggc ttctggaagt
     8761 catacttaat ctgagctctc ttacagtgct tacacttagg aggttgatag tccaatgtag
     8821 cgatgacttc gatatgtgta tcatgctgga tagccttatc gaaggtgata ttttgatctt
     8881 taattccgat gagtagtgtg gtatgatgaa tctgttccat aagacacttt ctaatgatgg
     8941 tctggtcgct tttcatgata agccttatgg gactttttgt gtactcaaaa gccctataat
     9001 ctccatagtg gacttaccca ctacagaaat tataaagccc taaaaaccaa tctgaggttg
     9061 ttgcaacagg attggttttt tcttgtgatt gcagatcaga cttttcaaaa gaacaagcac
     9121 attatctcag ctagactggt gcttgatagc tcctgagccc ttgtttgctg tagttgatag
     9181 gactttgctg atggcctagt caggcatatc gtatcaaatt caagtttttt catgtcactg
     9241 tctatagttt gtctgcccta ctttaggtag aatagaggta acttaagaga ggagtttatt
     9301 atggaattaa cgatgctttt gatggtttca gttttcattg cagggctgtt atcattcttt
     9361 tccccttgta tctttccagt tctgccggtg tatttaggca ttttgttaga ttctgatgat
     9421 tctaggtcta ttactatttt tggcaagaaa ctatattggt acggtattgt taagaccctt
     9481 gcttttattt caggtctatc taccattttt atcattttag gctatggggc tggtttactg
     9541 ggtaatattt tatatgctgc ttggtttcgc tacctacttg gtgcctttgt gattttgtta
     9601 ggtattcatc aaatggaaat cgtaaccatt aagaagctgc aatttcaaaa gagcgtagca
     9661 tttcaaaata agaaggaccg caatgctgtt ttaaatgcct ttttgctggg aattaccttt
     9721 agctttggtt ggacgccctg tgttggacca gttcttagct cggtgcttgc cttagcggct
     9781 tcaggtggca gtggggcttg gcagggtggc ttcttgatga ttatttatac cttgggctta
     9841 ggcctaccat ttttactact atcttttgct tctggtattg tgttgaagca ctttaataaa
     9901 ttaaaaccac acattcctct attgaagaag ttaggtggct tacttattgt tataatgggc
     9961 ttactgttga tgacaggaaa tctcaatagt ttatcaggtt tatttgaata aaggagaaga
    10021 aacaatgaaa aaaacaacat ttttaacaac aggcttagca tgtcttgctt tattaactgc
    10081 atgttcggcg aaggataaaa tggccatgaa tgatagtaaa aaagaccata tgaccaggac
    10141 cgatgacaaa tcaaagatga aaaaggatca aaaagacaag atgtcagaca agaaggatat
    10201 gatgtcagat gacaagcaca tgtcagatgc tgacaaggct agtaagaatg atgggcaaat
    10261 ggctccagat tttgaattaa agagcattga tggcaagact tatcgtttgt cagattttaa
    10321 aggtaagaag gtttacttga aattttgggc ctcatggtgt tctatctgct tatcaacctt
    10381 aggtgataca cagtcattag ctacgatgaa ggataaggat tttgaggtct taaccattgt
    10441 ttcacctggt catcagggtg aaaaatccga ggctgatttc aaaaaatggt ttgaaggaac
    10501 agactttaag gatttaccag tcttgctcga tccagatggc aagctgctag aggcttatgg
    10561 tgtgagatct tatccaactg aaatttttgt tggcagtgat ggtgttttag ctaagaagca
    10621 tattggttat gcaaagaaat cagagattga aaaaacctta aaggagatta aataagcaaa
    10681 ggaggctgtc tcatggaaca caaatggaag ttattgctac tcgtttttgg agccttagta
    10741 tttttaggag gtgttttgat ggtctttcaa agaggctacg ctactagcta ccataataat
    10801 caggtcaagc tgcctgccaa agggacgtct cagctcaaga agactgctaa tgccaagctg
    10861 cctgagaaga aaaaggagat ttaccttgca ggaggctgtt tctggggtgt ggaggagtat
    10921 ttttcaaatg ttgatggtgt tctagatgct gtttctggct atgctaatgg tagaggcgac
    10981 acaacctctt atcaattgct gcaccagaca ggacatgctg agacggttca ggttgtgtat
    11041 gatgctaatc ggattagctt aaaggagctt cttttacact actttagaat cattgaccca
    11101 acaagcctca ataagcaggg caatgatcgt ggcagtcagt accgtacagg catttattat
    11161 acggatccat ctgatttgac tactattgat atggtctttc aggaaaaagc ttcggattac
    11221 aaaaagaaaa ttgttgtgga aaaagctccc ctaaagagct ttaccaaggc tgaggaatat
    11281 catcaggatt acctcaagaa aaatcctaat ggctactgcc atattaatgt caacgaggct
    11341 tcatacccag tgattgataa gacaaaatac cctaagccaa gtaaggaaga gattaaaaag
    11401 aagctatcaa aggatgaata tcgtgtgacc caaaacaatg aaactgaaaa agccttttca
    11461 aacaggtact gggattcctt tgaagcaggg atctatgtag atgtggtcac tggtgagccg
    11521 ctgttttctt ccaaggataa atttgaatca ggctgtggct ggccaagctt tagcaggcct
    11581 attagcccag atgtgctacg ctataagaca gacaagagct tcaatatgaa ccgtacagag
    11641 gtgagaagcc gctcaggcaa ttcccattta ggtcatgtct ttaccgatgg tcctaaggat
    11701 cagggtggtc tgcgttattg tattaacagt ttatccattc gatttattcc aaaggctgaa
    11761 atggaagcta aaggctatgg ttacctttta acagcagttg attagaagat tatcctaaga
    11821 tttgttataa taagatgagg aagcacagat ggttgattat agttattaag acctgaagat
    11881 tacttcagtc gatattgcta aatgtgatca ggctcatgcc ctttagtctt gcttaagagg
    11941 tagtagcttt taaaagagtg attacgataa gaggcatttg ctcagagctt gtcctattta
    12001 gctcttgtcg agctatgtgc agagcttgta tgactatggt cactaagcat tagaaatagt
    12061 aggagaaatg gtgtgtactc attacttatt gttgaagacg aataccttgt gcgtcagggt
    12121 attcgttctt tggttgattt tgaccaattt gccatcgatc gtatagcaga ggctgagaat
    12181 ggtcaggtgg cttgggagtt gttccaagaa aatccttatg acattgtttt aacagatatt
    12241 aatatgccaa agcttaacgg cattcaactg gcagagctta taaaggcaag ggctccaaag
    12301 actcatcttg tttttttgac aggttatgat gatttcaatt atgccctatc tgccttaaag
    12361 ctaggggctg atgactacct gctaaagcca ttttccaaat cagatgttga agaaatgctc
    12421 aaaaagctaa agcagaaatt agaaaagctc aaaaaaacag aggcccttca aaaactagtt
    12481 gataagccgc agcaagaagg ctcagaaatt aagctagcta tccaagagcg tttagctgat
    12541 tcaagcctaa cgctaaagag cctatcaagc cagttaggct ttagccctaa ctatctaagt
    12601 gttttaatca aaaaggatct aggtttgcct tttcaggatt acttgattca ggagcgtctt
    12661 aaaaaggcta agctcttatt attaacaacg gatttgaagg tttatgagat agcagagcag
    12721 gttggctttg aggatattaa ttatttttcc cagcgcttta agcagttggt tggaatgaca
    12781 ccaaggcaat ataaaaaagg agaaggccaa tgaagcgcta ccctctttta gtacaattag
    12841 tgagttattt ttttctgatt gtgatttcac taatcactat tctgggagtg atttattatc
    12901 agaccagctc tcataatatc aggcagctca ttgaacgcga aaccagacag agcattcggc
    12961 agagctctca atttattgat gcctacatta agccattaaa ggagacaacc tcagccttag
    13021 ctagccatgc tgagattcag agctttgcta aggcagctaa cagtagtcat caagagcagg
    13081 tgttggcact gatgacaact gtgctgtcga ccaattcaga cctgcgctca gcggttctgg
    13141 tgacaaagga tggtcgtatg gtcacaacca acccaaagct aatcatgact acctcgcatg
    13201 atatgatggc agagccctgg tacaagtcag ctattgaccg caaggccatg ccggtgttga
    13261 cccctgcaag gcagctgtcc tcgcattcta aaaaggattg ggtggtttca gttactcagg
    13321 aggtagttga tgagacaggg aacaatttag gggtgctgcg attggatatt ggctacaata
    13381 ccatcaaatc ctccctagat caattgcagc ttgggcgtag gggctttgcc tttatcgtca
    13441 atgataagca tgaatttgtc tatcactcta aaaataccgt ctatagctca gagcgagaaa
    13501 tggccgcaat gaagccttac cttgctgttg ctgatggcta tacaaagcct aaggattatt
    13561 ttgtttacca aagggtgatt ccagacagtc aatggacctt gattggagtt gcctctttgg
    13621 atcagctgta tcatgtgcag cggcagattt tttggtcctt tttagggacg ggtctgcttg
    13681 caactgtcat ctgtggtctt gggacagtat ttgttctgag aagctggatt ggtcctatca
    13741 ggaggcttca ggctctcatt ttagctattc aaaagggtaa ccgtcagctg cgtgctgagg
    13801 aaattggctc gcctgagtta gctgatttgg cacgtcagtt taacgccatg ctggatcaaa
    13861 ttgatagttt gatgatttca gttgctgaca aggaaaaggc tattgggcag tatcgtctgc
    13921 aagccttagc cagtcaaatt aatcctcatt ttttgtacaa caccttagat actattattt
    13981 ggatggcaga gtttaatgac agccagcgtg tagttgatgt caccaagtct ctggctaagt
    14041 atttccgctt ggccttaaat cagggaaatg aattgattag ccttgctgat gaattggatc
    14101 acgctcgtca gtatttgttt atccaaaagc agcgctatgg tgacaagctg cactatgaga
    14161 tcaaaggtct tgagaaatac caggacttta tgattcctaa gctgattctt cagcccttgg
    14221 ttgaaaacgc tatttatcat ggtattaagg aggttgatag acctggaatg atcagagtaa
    14281 ctgtattaga agctgatcgt catgtgatat tatccgtttg ggataatgga aagggcataa
    14341 gcttagctga tgacagcagt caggccctgc ttgagtgtgg cggtgttggt ttaaaaaatg
    14401 ttgaccagcg cttgaaatta cagtatggtc atctctatag aatggcaatc actagcgagc
    14461 aggctgtttt tactgagatt aagctttatc ttcccaagcc gcttgatggc ctaaatgagc
    14521 tcccctaatc aatctgccct tagtagaaca aggaaaagag aggtttatgt ctttagaatc
    14581 cgattatttt aagcgaaaaa gtcctgtatt tgaggccctt atcccttatg gctttaccca
    14641 agagggtgac acttattgtt atcaggagtc atttatggag ggagatttca aggccttgat
    14701 tacgatcaag tcgtctggtc agctctcagc tagagtgatt gatactgacc ttggggagga
    14761 ctatctcccc ttgagaaatg atagacagca gggagtttat gttggtcagg ttcgtcaagc
    14821 ttatctagag cttcttggac gtttatcagc tgcctgcttt aggtctaccc cttttcagac
    14881 aaggcaggcc aaccaagtgg caacaagcat tagccagcag tggaatgatc cactagatta
    14941 cccctttgaa aaattcccta atattgccac ttatcgtgtt tctggcaagt ggtatgcgat
    15001 ggtattgccc ctgctagccg ataaattagg acaggtgcca aaggtcttac aggggcaaat
    15061 ggttgaggta ttgactgtta gaattgctcc taatcagcta acacacctct tgcagcaacg
    15121 tggtgtttac ccagcctatc atatgtctaa aaagacctgg attagcctat tactagatgg
    15181 tacactagca gatgatcagc tctgggagct agtcacgaaa agtcgtcaat tggctaatcc
    15241 taatggccta gcaaacccag atggaccaga ttactgggtg attcctgcta atctcagcta
    15301 ttacgatatt gacgcggaat ttgcagctaa tcctgacatt ctctggacgc aaaaggcttc
    15361 cataaaagct ggagactatg tttttattta tatcactgca ccgaccagat caattcgcta
    15421 tgcctgtcag gtcttgagat cagacattcc taatcaaggc tatcggaaaa atgcgaagat
    15481 taagacctta atgtcgctac gcttgttgca ttgctacgaa gatggtttga tttcccttga
    15541 tttgatgaaa cagtatgggg ttaatgctgt tcgcggtcca agacggttaa gcccacaatt
    15601 agttgcattt ttgaaggaaa aagagtattt taaagatgtg aaacaaaaag aatgataagg
    15661 agagcgggta tgactcaatt tatagcagat cagagctttt gggaattatt tcctgatgct
    15721 aagctaggtg ttttgttgct caggaactat gacaatcagg aagactcccc acaagaggtc
    15781 aagcaattat tggcagacag ccatgacata gctaagcagt atttgactga agagtcgttt
    15841 agtgacaatg agatcattca ggtctatcgt caagcctatc agcgttttaa gacaaaaaag
    15901 ggagccagat ccagtattga ggccctccta aagagggtgg caaatggtca agtcctatcc
    15961 tccattaacc ctctggtgga tatttacaat acagccagtc taaggtttgg tctgccagtt
    16021 ggcgcagaag atagtgattg ctttgtaggt gacttacgcc tgacgttaac agagggaggc
    16081 gatgagtttt acctcattgg tgattctaaa aacagtccaa ctctgccaaa tgagctctgc
    16141 tacaaggacg atgctggtgc tgtttgccgc tgcctaaact ggcgcgatgg tgaaaggaca
    16201 atgattaccg atcgcactaa aaatgccttt ttagtcattg aagcattaga tagcaagacc
    16261 caagcaagac tacaggacgc ccttaagttt atcgaagaca aggctaagtg ctacctgaag
    16321 gcagaaacag cactatatac gctggatcaa gcctcaccaa gtatcacgtt ttaatcaaaa
    16381 aaagctagga agccagtatt cctagttttt tcagttgttc aggtgctttt atttggtgtt
    16441 gtcgagggag atttccttat agctgcaaga tatgacatga cagggaaaca gtttttgctt
    16501 gtttgatcta atcaagcgat taataaaagc ttttaagctg ttggttatgc taaagggctt
    16561 tcttaatcct atcagagaac tttaaaaaat agtataatgt agttaactta tgatgatagc
    16621 taaggaggtc agcatggagt tatttgacaa ggttgatgat acgttaaagg ctttagcgat
    16681 tgactaccag ctggttgagc atgagccagc tttaaccaca gagcaggcag accagttcat
    16741 agagggcatt gaaggggtta gaaccaagac aatgttttta acgaccagga aaaagaacca
    16801 tttttatctg atcattatgg atgatactaa gagactggat atgaatcgct tcaaggagct
    16861 tgttggagaa aagcagatta aaatggcatc agcagaatgc ttgcttgcca agatgcagct
    16921 gccaccagga gttgtttctc cttttggtct tttaaacaac gaggataagg atattcaggt
    16981 ttacgttgat aaagctattg ctcacgaagc tagaatgagc tttcacccaa ataccaatga
    17041 caaaaccatc tttattcaaa cagatgacct ctttaagttt ctagcggcta taggttacgc
    17101 ggtcaatatc gtggatctat agctaaattc aaggttcttc tagcggttct tgctcacatc
    17161 agttcacaaa gctggtggcc tagccaatcc agggcaaaca aaaagcacaa tagcctttct
    17221 tgactactga gaatagccag tagacccttg tgtcatatgc ttatctggta tttgagctta
    17281 aatctcaagg cttttaagta gaggatcaaa caaagaaaac gaccagcaga ccttgcgtga
    17341 tgactgatta tcaagtctgg taggagctaa aatcagtcat ggtcttgagg cctaaaacgt
    17401 cccatttgtc gctcctgttg ctagggcatt agttgacatg tatacccacg actaaccaag
    17461 ccgaggagag ctgtcgctcc cttctcagga gcgtggattg aaatgcaaaa gggatctgat
    17521 agacatttct gcttttaaag ctagtccatc aaaaaaacgc atgacaccac tgtagtggga
    17581 catcatgcgt ttttgctaag ctaaagtgat ttgacgcttc ctttgaaagg gttatttatt
    17641 gctgaagaaa aagggtggtg tgtaatggct caggatttca aagcaagctt tggcctgctc
    17701 attgtcctca cagataatca gacaggtatc atcaccacag atagtggcta cgatttctga
    17761 gatttgcata gcatcaagga tagagccaaa ggattgtgcc agccctggta aggtttttaa
    17821 aataatctga tgctgaacaa ccctgagcat gacaagggcg tcctccatat aaaagcgcaa
    17881 acgatgctcc caacgcgtct gagaaatggc cagcgcttca taatgcgtgt cattaccagt
    17941 tgtaaccttg acaaggttaa gctctttcat atcacgtgat aaggttgcct gtgtgatgct
    18001 tatcccattt tttcgtaagc gttcctgtaa ttcctgctgt gtgtgaatag ttgtttcaga
    18061 aattagagat cgaattaatt gatgacgtgt ttctttttta ttcatttctt ataatattcc
    18121 cctaatgatt agtaacattc agagtataac aaaaagatgg cagtgtgtaa agttttagat
    18181 gaaccgctta caaaaatagc ctttttatgt taaaataaaa cgggtgctta gaaaaggaga
    18241 tttgcgtgat tcgaagagaa gattatcaat accttagaaa acttgatgat ttctgtcatt
    18301 tttcaattga acaatttgac aagattgtcg gccaaatgga atttagacaa gctaaaaagg
    18361 atcatatgtt attttttgaa ggtgataaga gggacagact ctttttagtg acctcaggtt
    18421 attttaagat tgagcagtca gatcggacag gaacctttac ctatactgat ttcatacgac
    18481 atgggacaat ttttccctac ggggggctgt ttacagatga ctactatcat ttttcggtgg
    18541 ttgcgatgac agatgtcacc tacttttatt tcccgactga tttgtttgag gactattcct
    18601 tgcacaatca gcagcagatg aagcatctct acagtaaaat gtcgtccttg ctggagcttc
    18661 atgagctcaa ggtgcgcaat ctcatcacct ccagtgcaag ctcacgtgtg attcaatcct
    18721 tggctatttt actggttgaa atgggaaagg atagcgatac tctgcctttt cagctgacga
    18781 ctactgacat tgcacaaatg agtggaacaa ccagagaaac cgttagtcat gtctttagag
    18841 atttgaaaaa ggaaggcttg attgcagtca aggggaaata cctcacctac ctagataaaa
    18901 actattttct gcagtacaca acctaagatc aagtcaaaag gcttcgctta aaaagttttt
    18961 tgactttttt caatttataa atataagatt tttcgttaaa atgtaaaaaa caaacaagaa
    19021 aacgtataca aaaacataaa cattcatttt caggcgaaaa agtgtaatcg tttacacaga
    19081 ttggctgtga gaaataccct atttttgaat gctgcttgga gtaaactagg ggtgtaagca
    19141 aaagctaaga gtcttagcag tgaattcaca aaacattaga aagaggtaat tcttatgact
    19201 gctcaaacac cgattcatgt ttactctgaa attggcaagc tgaaaaaggt tttgctccat
    19261 aggcctggca aggaaattga aaacctgatg ccagactact tggaacgtct attatttgac
    19321 gatattccat ttttggagga cgctcaaaaa gagcatgatg cttttgcaca agcattacga
    19381 gatgaaggcg tagaggtgct ataccttgaa acactagctg ctgaatcact tgtaacacca
    19441 gaaattcgtg aagccttcat tgatgaatac ctaagcgaag ctaatattcg tggaagggca
    19501 actaaaaaag ctattcgtga gctactgatg tctattgaag acaatcagga attgattgaa
    19561 aaaacaatgg caggtgtgca aaaatcagaa ttgcctgaga ttccagcagc agaaaaaggc
    19621 ttgactgact tggttgaatc aagctatcct tttgcgattg acccaatgcc aaacctttat
    19681 ttcacacgtg atccgtttgc aactattggt acaggtgttt cgcttaacca catgttctca
    19741 gaaacacgca atcgtgaaac aatctatggt aagtacattt tcacacatca cccaatctac
    19801 ggtggcggca aggtacctat ggtttatgac cgtaacgaaa ccactcgtat cgagggtgga
    19861 gatgagctgg ttctttcaaa agatgtgctt gcagtaggta tctcacagcg gacagacgca
    19921 gcatcaattg aaaagctctt ggttaacatc tttaaacaaa atcttggctt caagaaggtt
    19981 ttggcctttg aatttgctaa caatcgtaaa ttcatgcacc tagataccgt ctttacaatg
    20041 gtggattatg ataagttcac gattcaccca gaaatcgaag gagatcttcg cgtttactca
    20101 gtgacctatg aaaatgaaga gcttcgtatt gtagaagaaa ctggtgattt ggctgagctt
    20161 ttagctgcta atctgggagt tgagcgtgtt gagcttattc gctgtggtgg tgataacctt
    20221 gtggcagctg gtcgtgagca atggaacgac ggctcaaaca cgctaacaat cgcaccaggt
    20281 gtcgtggttg tttataaccg taacactatt acgaatgcca ttcttgaatc aaagggcttg
    20341 aagctcatta agattcatgg aagtgaattg gttcgcggtc gtggtggacc tcgttgcatg
    20401 tcaatgccgt ttgaacgtga agacatctag gagaggcaaa tgacaagggt tattgttgga
    20461 aatcagcctt ttcaacgggc agctagctta tatattcgct atcaggtttt tgtcttagaa
    20521 cggcagattg atcggcaaga tgaatttgat tgcttcgacg ataacgatcg cgtgtatgca
    20581 gtcttgtatg atggtgatca gcctgtatcc acagctcgct ttttacccac agctaaagat
    20641 caggctcgtc taacaagagt tgctacgctg cgtcagtatc gtggtagggg ctatggtgcg
    20701 caggtgatag aagcgcttga gcagtatgcc agagagcaag cttacgagcg attggttatt
    20761 catagcgaga ttagcgcaca gtcattttat gaaggtcttg gctatcaagc ctttggcgag
    20821 ccttatgatg aagacggtga gccttgtcaa tcagtagaaa aatatttata aaaaggagaa
    20881 tttaaatgac acaagtattt caaggacgta gcttcttagc agaaaaagac tttacacgtg
    20941 aggaatttga atacctcatt gattttgcag cacacttgaa agaccttaaa aagcgtggta
    21001 ttccacatca ctatttagaa ggtaaaaata ttgccctctt gtttgaaaaa acatcaacgc
    21061 gcacacgtgc tgcctttaca actgcggcga ttgatttagg agctcatcct gaataccttg
    21121 gcgctaacga tattcagctt ggtaaaaagg aatcaacaga ggacacagct aaggtattgg
    21181 gtcgtatgtt tgatgggatt gaattccgtg gctttagcca acgtatggtt gaagaattgg
    21241 cagaattctc aggtgttcca gtgtggaatg gcttgactga tgaatggcac ccaacccaaa
    21301 tgcttgcgga ctaccttact gtcaaggaaa actttggtaa gcttgaaggc ttgaccttgg
    21361 tttactgtgg tgatggacgc aacaacgttg ctaattcact gttagtagca ggtaccttac
    21421 taggtgtgaa tgttcatatc ttctcaccaa aagagctctt cccagcagaa gacatcgtga
    21481 agctggctga gggctatgct aaagcatcag gtgcgcatgt gttagttact gacaatgctg
    21541 atgaggctgt aaagggcgca gatgtgcttt acactgatgt gtgggtgtca atgggtgaag
    21601 aagacaagtt tgaagagcgt gtgaagctct tgaagccata tcaagtgaac atggagcttg
    21661 ttaaaaaagc cgccaacgac aaccttatct tcttacattg cttgccagcc ttccatgaca
    21721 caaatactgt ttacggaaaa gacgttgctg agaaatttgg tgtagaagaa atggaagtaa
    21781 cagatgaggt cttccgcagc aaatacgctc gtcactttga ccaagcagaa aaccgtatgc
    21841 acactattaa agcggttatg gccgcaactc ttggtaatct tttcattcca aaagtgtaag
    21901 ctgtgattgg taccttttaa tttattttag ctcatttcat taatttaaca tttaactact
    21961 aaaaaacgta ctttaactac atgacgagtc gttctggttc tcgtgtcctt gaccggaact
    22021 gggacggctt atttttatga aaaggtaaga ggtaatcact atgacagaag aaaaaaaacg
    22081 aggttttaaa attccttctt cttacactgt tttgtttatc atcattgcta ttatggcagt
    22141 attaacctgg tttattccag ctggtgctta tgagactgct aaggatggcg gtgtgatttc
    22201 agggacctac caaacggtta agtcaaaccc tcagggcttt tttgacattt taatggcacc
    22261 tgttcgaggc atgctaggtg tcaaagggac tgaaggggca attcaggttt ctttctttat
    22321 tttgatggtt ggtggctttt taagggttgt caacaagaca ggtgcgcttg atacagggat
    22381 tgcttctgtt gtgcgtaaaa ataagggtag agaaaagctg cttattgcga ttttgattcc
    22441 tttgtttgca cttggtggca caacctacgg aatgggagaa gaaacaatgg cgttttaccc
    22501 tcttcttatt ccggtaatga ttgcggttgg ctttgatagc attgttgcag tagctattat
    22561 cctgattggt tcacagattg gctgtttggc ctcaaccatc aatccctttg ctactggagt
    22621 ggcagcagat gcagccggtg ttagtatcgc agatggtatg atttggcgga ttatccaatg
    22681 ggttgtcctt gttggtatgt ctatctggtt tgtttacagt tacgctagca agattgaaaa
    22741 agacccaagc aagtccttgg ttgctgacaa agctgaagaa cataaggaat tcttccagct
    22801 gcaaaattcc ggtgaggatt tgactagtcg tcaacgaaag gttttagcca tttttacctt
    22861 gacatttgtc atcatgattc ttagcttgat tccttgggaa gattttgaca ttcaattatt
    22921 tacaaatatc aacacttggc taacaacaac acctgtttta ggtggtatta ttggtaaaac
    22981 aatgggagcc tttggtactt ggtatttccc agaaattacc atgctcttta tcatgatggg
    23041 tgttttagtg gctgttgttt atcgcatgag tgaagatgac ttcttctcag cctttctaag
    23101 tggtgcaggt gagttcctcg gtgttgcgat tatttgtgcg gtagcgcgtg gtatccaagt
    23161 gatcatgaat ggtggtatga ttacagcaac cattcttcat tggggtgaaa caggtcttgc
    23221 aggcttgtca tcacaggtct ttgttgtctt ggcctatatt ttctatttgc caatgtcctt
    23281 cttgattcca tcaacatcag gacttgccgg tgcaacaatg ggaatcatgg ctccgcttgg
    23341 acaattctca aatgttcctg ctcatttggt tatcacagcc ttccaatcag catcaggtat
    23401 cttaaacatg atttcaccaa cctctgctat tgttatggga gcgctcgcac ttggacgtat
    23461 tgatctaggt acttggtgga aatttatcgg caagtttatc gttatggtaa tgcttgttag
    23521 tgttttgttg ttagtagtag cgacattctt ttaagagata ggaggctcct atggaaacct
    23581 atatccaacc aagacaccaa gaggcttgtg tagccgcgat taaaaaaata gtatcttacc
    23641 cttctgtgct aaatgagggg gaaaatgaca caccctttgg ccaagccatt caagatgttc
    23701 ttgaagcaac cttagccctg tgccaagatc ttggttttaa tacctatatt gatcctaaag
    23761 gctattatgg ctatgctgaa ttgggcgatc aaacagaggt gcttgctatc ctttgtcact
    23821 tagatgtggt gcctgctggt gatttgaagc tgtggcataa agatcccttt acttgtattg
    23881 aaaaagatgg ctgcttgtat ggacgtggca ctcaagatga caaggggcca tcgatgatgg
    23941 cactctttgc cactaaagca cttatggacg ctggtgtggt ctttaacaaa cgcattcgct
    24001 ttatctttgg aacagacgaa gaaaccctct ggcgctgtat gaaccgttat aatgaagtag
    24061 aggaggaggc aacctttggt tttgccccag actcaagctt cccattgacc tatgctgaaa
    24121 aggggctttt acaagctaag ctagttggta agggatcgcc taaactcaat cttgaggtgg
    24181 gtcaggccta taatgtcgtt ccagctagag cctcttatca gggagacaag ttggaggcat
    24241 taaaggaaga gcttgacagg cttggctttg aatatgttgt caaagatgac gagctaaccg
    24301 tctatggact tgctcagcat gccaaggacg ctccagatgg gattaatgcc cttatcaggc
    24361 ttgcaaaggc tcttgtagtg cttgagccag agccagtcct tgactttctt gctcatgtgg
    24421 ttgatgaaga cggcagagca gtcaatattt ttggtccagt tcaggacgag ccatcaggag
    24481 ggcttagctt caacgtagct ggtcttacct taacaaaaga gatgacagag attcgtttgg
    24541 acattcggat tccggtctta gcagataaag ataccttagt agaccagtta agccaaaaag
    24601 cgcaggacta cggtctagct tacgaggaat ttgattattt ggcaccctta tatgtgccct
    24661 tggacagcga gctagtaact accctgttag aggtatatcg taaaaaaaca ggggaccaat
    24721 cgccagccca atcatcaggt ggagcaacct ttgctcgtac aatggctaat tgtgtggcct
    24781 ttggagcatt atttcctgat gctgttcaaa cagaacacca agaaaatgaa catatcgtct
    24841 tagcagatgc ctatcgtgca atggatattt acgcggaagc catctaccga ctaacacgat
    24901 aagatgagga gtatcatata tgacaaaaca aaaaattgtt gtcgcacttg gaggaaatgc
    24961 aatcctctca acagacgcgt cagctaaggc acaacaagag gccttggttt cgacatcaaa
    25021 atcactagtg aagttaatca aagaaggcca tgaggtgatt atcacgcatg gcaatggtcc
    25081 gcaggttggt aatctcttat tgcagcaggc agcagctgat tctgagaaaa atccagccat
    25141 gccattagat acctgcgttg ccatgacaga aggcagcatt ggcttttggt tagtcaacgc
    25201 cctagacaat gagctgcaag cccaaggcat cacaaaggaa gtggcagcag ttgtcaccca
    25261 ggtcattgtt gatgaaaatg accctgcctt taaaaatccg actaaaccaa ttggtccttt
    25321 cttaaccgaa gaagacgcta aaaagcaaat ggcagaatca ggtgctagct ttaaggagga
    25381 cgctggtcgt ggctggcgta aggtggtgcc atcaccaaag ccaattggta tcaaagaagc
    25441 taatgtgatt agaagcttag ttgattctgg tgttgtggtg gtcagtgctg gtggtggcgg
    25501 tgtgccagtt gttaaagacc ctgcaagtaa aacgcttacc ggtgtggaag ctgttattga
    25561 taaagacttt gctagccaaa ccctttcaga attggttgac gctgatctct ttattgtctt
    25621 gacaggtgtt gataatgtct atgttaactt taacaagcct gatcaaagaa aattggaaga
    25681 ggtaacggtt tctcaaatga aggaatacat cgctcaggac caatttgctc ccggaagcat
    25741 gctgcctaag gtggaggctg caattgcttt tgtggaaaac aaatcaaatg ccaaagctat
    25801 catcacatcg ttagaaaata ttgacaatgt tctctcagca aatgctggta cacaaattat
    25861 cgcaggctaa ttcagatgac tgcacaatga gcttaggctt ttgtgctttg ataggtttta
    25921 gctgataagc ttgaaaaatt gatttaaaag gttaaattag gttaatttag ccttttcttt
    25981 tacttttaat cggtgtataa taagcgtaat atttttttat ttttactcat gattagaatg
    26041 gtaaaaaata aaggtgactt agtcgcgaaa atgatttaaa ggaggagcta tgaaaaaaag
    26101 ctttattcat caacaagagg aaatttcctt tgttaaaaat acatttacgc agtatttgat
    26161 tgctaagctt gatgttgttg aggtgcaagg tcctatttta agtagggtcg gagacggcat
    26221 gcaggacaat ttatctgggg ttgaaaatcc ggtatctgtc catgtcttga acattcctaa
    26281 tgcaaccttt gaggtggtgc attcgctagc aaaatggaag cgtcatacct tagcacgttt
    26341 tggctttaat gaaggtgaag gtcttgtggt gaatatgaaa gcgctccgtc ctgatgaaga
    26401 ttcgctagac cagacgcatt cagtgtatgt ggaccagtgg gattgggaga aggttatccc
    26461 tgatggtcag cgcaatctag cttacctcaa agaaactgtc gaaacgattt acaaggttat
    26521 ccgcttgaca gagctagctg ttgaggcacg ctatgatatt gaagctgtct tgccaaagaa
    26581 aattaccttc attcacaccg aggagcttgt tgccagatac cctgatttga caccaaagga
    26641 gcgtgaaaat gctatcacaa aagaatttga tgcggtattt ttgattggta ttggcggtgt
    26701 attgccagat ggcaagccac atgacggtcg tgcgccagac tatgatgact ggaccagtga
    26761 gtcagaaaat ggctaccatg gcttaaatgg tgatattctc gtttggaatg agtagctagg
    26821 cacagccttt gagctattct caatgggaat tcgtgttgat gaagaggctc taaagcgtca
    26881 ggtggacatt actggagatc aggaacgcct acaatttgat tggcacaaat cgctgctaaa
    26941 tggtctgttc cccctaacca tcggtggagg aattggtcaa tcgcgtatgg ccatgttttt
    27001 gcttcgtaaa aagcacattg gagaggtcca aacatcggtg tggccacaag aggttcgcga
    27061 tacctacgac aatattttat agatgatacg gaggctaggt ttttacctat agcctctatt
    27121 tttgtcccta agtgatgctt cattagagct catttagtgc taagcaggct cgtcagttat
    27181 ataataggtc aaaaatttga aaaaatgaat catttttaag gcttgacact agatttttgt
    27241 tataatatca gttatgagaa ttgtatcagg tgaatttgga gggcgtcccc taaaaacgct
    27301 cgaaggcaag actactcgac ccacatcaga taaggtacgt ggcgcgattt ttaatatgat
    27361 tggtccttat tttaagggcg gacgtgtctt agacttgttt gctggatcag gtggcctatc
    27421 aatagaggct atttctaggg gcatgtcaga ggcagtgctg gttgagcgtg atcgtaaggc
    27481 gcaagccatt atccaagcca atattaagtt gacaaaagct agccagcaat ttacgctatt
    27541 aaaaatgaac gctgagcgtg cacttgatca cttatccggt cagtttgatg tggtgttttt
    27601 ggacccacct tatgctaagg aaacgatagt agccaatata gaggccttgg tggagaaaaa
    27661 tcttttaagc gacgatgtga tgattgtttg tgagacggat cggtcggtag ctctgccaga
    27721 ggcaattgcc tggctaggga tctggaaaga aaaacaatat ggaattagca aggtaacagt
    27781 atatgtcagg taagattgga ctttatacag ggtcatttga cccagtgaca aatggacaca
    27841 tggatatgat taagcgtgct agccatttgt ttgagcatgt ttatgtcggg atttttaaca
    27901 atccaaataa gcagagcttt tttacttttg agctgcgagc tcaaatgcta agcgaagcgg
    27961 tttgtgcctt gccaaatgtg acagtggttt ctgccgagca tggtcttgca gttgacctgg
    28021 ctagggagct gtctgtgacc caccttatcc gagggcttcg caatacagct gattttgact
    28081 atgagatagg cttagagtat tttaatcata gactagcccc tgatattgag accatttacc
    28141 tgatggcgac tcatgacctg cagcccgtta gctccagtcg tatcagagag ttgattgcat
    28201 ttagagcgcc aattactggt ttggttccgc aggctgttat taatcaagtg gagaaaatga
    28261 atgaaaacaa taaaaaaaat taaatggtgg ctgattggct ttgttgcctt gctttttcta
    28321 ctgttgacac tgtttttccc cttgccttat tatattgaaa tgccaggtgg agcctatgat
    28381 attcgctcgg tattgactgt caatggcaaa gaggataagg aaaagggagc ttatcagttt
    28441 gttgtagtga gcctcagtcg ggccaccttg gctaaattgc tctatgcttg gctaacgcct
    28501 ttcactgaga ttagcaccat ggaagatact actggtggct atagcgatgc tgactacctg
    28561 cgaattaatc gcttttatat ggaaacctct caaaacagcg ctgtttatca ggcccttact
    28621 ctagcaggca aggaggtaag ctttgattat aagggtgttt atgtcttaga cgtcagcaag
    28681 gattctagct ttaaaggtgt gctgcaccta gcagatacag tgacaggtgt caatggtaaa
    28741 acatttacaa cgtctgccga tctgattgat tatgtttctc atttgacctt gggagatgag
    28801 gtgcaggtac aatttacaac cgctggtgag tcaaagactg aaaaaggaaa gattattaag
    28861 cttaaaaacg gtaaaaatgg gattggcatt accctgacag accacacaca ggtcatttct
    28921 ggtgatgagg tcgactttag cactggaggt gtgggtggac caagtgcagg cttgatgttt
    28981 actcttgata tttatgatca aatcaatcac gaagacttgc gcaagggacg tgtgattgct
    29041 ggtacaggaa ccattggcaa ggatggaaaa gttggagata ttggcggggc gggcctaaag
    29101 gtggctgccg ccgccgctgc tggtgctgat attttctttg ttccaaataa tcctgtgcat
    29161 aaggacgtca aaaaagcaaa tcctaaggct attagcaatt acgaggaggc taaaaaagca
    29221 gctaaacgac taaagacagc aatgaaaatt attcctgtga aaaccgttca agatgctata
    29281 agctacctta aaaaatagaa gcaatgcgaa gcaggctaat agggcatgct ctgtcttgct
    29341 tctagttggt ggaatttagc tagctcaaag gtcttgagac ctaagcataa ggtctagaca
    29401 gtattctaga gctagacctt atgcttgatc ctgaacaagg aagaccgcca aagaagaaca
    29461 aaatcctcag gccaaaagag cccgtaggga aatattgcca ttatctatca aggctttttg
    29521 aagaaaatca cttaaagaca gtagggcgtt aggctttact gtcttagttt ttcttgcctg
    29581 aagtcatggc tgctgatgat gttacatcaa ggcttactag ccagcagagc acaaggagca
    29641 gctttggctt aggtttattt tctctgctga ctagtaaaga aggttgctgt cagtctgctt
    29701 acaaaaacct aaaaatagtg tataataggt aggctatggg ctgtcaggag tcgctagcct
    29761 gcttacccag accagccctt tgagaagagc aagcatggct cttctcagaa taacccagga
    29821 ttaacagaca tcaaaattaa tgctaaggaa aggagctata tgaaaagaga tattttacca
    29881 gagatgtata attacaataa atttcccggt ccggaattta ttcattttga tcattatgtc
    29941 aaggctgaag gcattgagtt attgctgctg aaaaatgaaa aaaatgcttt taacacaacg
    30001 agctttggtc agcgcttcac agagatatta ttaaagtatg actatattgt tggagattgg
    30061 ggcaatgaac agctgcgtct caagggcttt tacaaggatc atcatgatgt caaaaaagct
    30121 agtcgtattt ctcgcctaga agactatatt aaagaatttt gtaactttgg ctgtgcctat
    30181 tttgttttgg aaaaccctaa tcccaaggac atgccaaaag aggaggaaag gccatcaagg
    30241 cgcaggaaat cgtctaaagc caatcgccgc agaaatcagc ctcagcatag tcagcaggca
    30301 cctgctaaag acaacttcaa aaagctaacc aaggataggt cagcggacaa gccaagcttt
    30361 accagcaaaa agcgcccagc tcctaataag accaagggaa accaaaggcg ctctcgtact
    30421 agtcaactga accataaaac ggatcacttt atcatcagaa agaaggacaa ttaatctatg
    30481 aaaccatcaa tctatggcct aacgcgcgac gagctaattg cttgggcgat tgacaatggt
    30541 caaaaggcat tcagagcgac acagatttgg gactggcttt acagaaaacg ggttcaatcc
    30601 tttgatgaaa tgactaacat ttctaaggaa tttgttgcca ttctaaagga cagcttttgt
    30661 attaatccct tgaagcagcg tgttgctcag gaatcagctg atggaacggt taagtatttg
    30721 tttgaattgc cagatggtat gctgattgaa acggttttga tgcgtcagca ctatgggcag
    30781 tcggtctgtg taactacgca ggttggctgt aatataggct gcaccttctg cgctagtggc
    30841 ttgattaaaa agcaacggga tttaaacagt ggtgaaatca ctgcacaaat tatgatggtg
    30901 caaaactatt ttgataagcg tgctcaagac gaacgtgtca gccatgttgt tgtgatgggg
    30961 attggagagc cctttgataa ttatcaaaat gtgatgacct ttcttcggac gatcaatgat
    31021 gatcatgggc ttgctattgg tgctcgtcac attactgttt caacctcagg cttggctcac
    31081 aagattcgtg aatttgccaa tgaaggagtc caagttaatc tggctgtgtc actgcatgca
    31141 cctaataatg agctgcgctc aagtatcatg aggatcaatc gttccttccc acttgataag
    31201 ctcttttcag caatcgaata ttacattgaa acaactaatc gtcgtgtgac ctttgagtat
    31261 atcatgctta ataaggttaa tgatggggta gagcaggcac aggaattggc agatttgacc
    31321 aaaaggattc gcaagctgtc ttatgttaac ctgattccct ataatcctgt ctcagagcat
    31381 gaccaataca gtagaagtcc taaggagcgt gtggcagcct tttatgacat tctaaagaaa
    31441 aatggagtga actgtgtcgt tcgtcaggag catggtacag atattgatgc tgcctgcggt
    31501 cagctgcgct ctaataccat gaaaaaggac cgacaaaaag cagcagctgc aaggacatga
    31561 tgacttggtc aaggttgctg atttgattga taggagatgg agataaaaat ctgacctcaa
    31621 ataaagcaaa caaataggtc tagttttctg agatcccgaa agcaggtctt gttcgttttt
    31681 taatgaatga gactaggtca taaagtacat gcgttaagaa tgtctaaagt gcagctcttt
    31741 ttgtcccagc ctccctcttt tatcttggta gcagttgtca agtaattgct aagcaacagt
    31801 gttttatctt tattggctgt aaaaaaagat atagtgcctt tattcacacc ttttctgaat
    31861 cacttgagcc ttgttctgac cgctcctttt ggtgcttctg atccatatag cctaagcttt
    31921 tcagagctat gaatcgaggc aaaataatag gtgttagccc tagctgcttg atgtagctag
    31981 ggcttttgtg acctagctgc cagtgagcct ttcaaatagc aatatggcta taaggcccag
    32041 tgtcagatag ggaataaaag ggattttctt agtttgtaga agtaggcagg ctagaattcc
    32101 gatcagactg gcaatttgga cgatccataa caaagagcta agcttgacca caagagcaag
    32161 attagctagg taaagaaaat ctccggcacc aatattgata ggaaaagcta cgcttagcag
    32221 tgcaagcaaa agcaatagca ctgttaacag gttaatgcta taaaatggca gcagaaacaa
    32281 aaagctcatc agccagatga gcaaaggata ctcttgactg tctaaatcaa aaaagcacag
    32341 tagcaaagag aagcatagga gataaagctg tgtccaggtc aagccgcaaa gggcagccag
    32401 tccgaaaatg aggctggtga ttatttctaa ataaggaagc ataacccagt gcttttgttc
    32461 atgcttagag ttgtaagtgg gctttgccat aggaaaaaag aggcttgaaa gatgaagttg
    32521 acctatatag agcttgaccc aagcctttgc ttgctgttca gaaaacaggt taagtattag
    32581 ccgaaagagg tttcccacaa gaaaaccaca atagcaataa aaaatagtgt tcatacttat
    32641 ttatccgaaa aacaatttaa attcttgcaa tattttaaaa aacggtgtac aatgaaacta
    32701 taaaacgaga atgattctaa ataagctgtt gatacttatc tgaattggct cgttatcgtc
    32761 gaatggagct gacaagagag tgacttttct tgctgcatac cattcatgcc cttttatatc
    32821 tatcagtaag gagagtttat tatgacaaac acactcgttg aaaacattta tgcatcagta
    32881 actcataata tttctaaaaa agaagcatca aaaaatgaaa aaaccaaggc tgttttaaat
    32941 caagcagtag cagatctatc tgtagcagct tcaattgttc atcaggttca ttggtacatg
    33001 cgtggtcctg gctttttata cctgcaccct aagatggatg agctattaga ccgcttgaac
    33061 gcgaacctag atgagatgag tgagcgcttg attactattg gtggggcacc ctactcaacc
    33121 ctagaggagt tttcacagca ttctaagcta gatgaaacaa agggaagcta tgataagtca
    33181 gtagctcagc atttagctcg tttggtagag gtttaccttt accttaccag tctttatcag
    33241 gttggtttag acattactga tgaagagggt gatgctgctt caaatgattt gttcacagca
    33301 gcaaaggctg acgctgaaaa gactatttgg atgctacagg cagagcgtgg tcaaggtcct
    33361 gctattttct aaagcgtcat acaactgata taacataaaa aaggcagagc gtggtatagc
    33421 cctgtctttt taacgccttt aaagtcagct attagtgcta gtgatgtcag gtctcacagc
    33481 ttttttatga tggatgacca acatttttag accttgtcac cacagcagag catgtggcat
    33541 ttagtccacc ttgggctcac gtcgatggtc ttacttatga tatatcaagg cttgtgacat
    33601 taccgttgcc ttttatcttc agtctgagct gctggttcct actgctgatg ctgcttgata
    33661 gtgttatagt gattttcaga aatatggaaa gcgattgcat aattgtcttg aaatctcatg
    33721 cgtaatttgc taaaatctag ttatatgaaa acattatacg atgtacagca gctgttaaaa
    33781 ggctttggta ttgttatcta catgggaaag cggctttatg atattgaaat gatgaaaata
    33841 gagctgcaaa ggctatatga tggtggcttg ttggataaac aggcttattt aactgctgag
    33901 ctgattttac gacgtgagca tcgattagag ctaaaaagag aagggcaaga aaatgagtca
    33961 aaaattgata gggattgatt tgggcggaac cacgattaaa tttggtattt taacctcaga
    34021 gggtgacgtt caggaaaaat gggcgattga gacaaatgtt ttagaggacg gtaaacatat
    34081 cgttccagat attgtcgcct cactcaagca tcgccttgac ctttatggac tgactaagga
    34141 cgattttatc ggtattggta tgggctcacc tggagctgtc aatcgcacag atcatactgt
    34201 tacaggggcc tttaacctca actggagagg cacccaagag gtgggatctg ttattgaaag
    34261 ggagctagga attccctttg ctattgataa tgacgcaaat gttgcggccc tcggcgagcg
    34321 ctgggtcggt gcaggtgaca ataatcctga tgtggtcttt atgaccttag gaacaggtgt
    34381 tggtggtggt atcatcgctg atgggaactt gattcatggt gtggctggag ctggtggtga
    34441 gattgggcac atgatagtag agccgcttaa gggctttgct tgcacctgtg gctcacaggg
    34501 ctgcctggag acagtggcct ctgctacagg tgttgttaag gttgctcgtc ttttagcaga
    34561 agcctacgaa ggagattcaa gcattaaggc agcgattgat aatggagagg ctgtctcaag
    34621 caaggacatt tttgttgcag cggaggctgg tgatgccttt gccaactctg ttgttgaaaa
    34681 ggtcagttat tatctaggac tggcagcggc taatatctca aatattttga accctgattc
    34741 ggtcgttatt ggcggtggtg tatctgctgc gggtgagttt ttacgttcac gtgttgaaaa
    34801 gtactttatg acctttacct ttccgcaggt tagacagtcc actaaaatca aaatagcaga
    34861 gcttggtaat gatgctggta ttattggtgc agctagcctt gcaagacaat ttatcacaga
    34921 ataggagtta atgatgtcac cacttacaat gattggctgg gtattgcttg cgggagtgat
    34981 tgcctattac ctttggaatt atgtttccta tagaagaatg gcaaagcagg ttgataatga
    35041 tacctttaag gagctgatgc gtcaggggca agtgattgac ctgcgcgatc cagcttcctt
    35101 tagggcaagg catatcctag gcgctagaaa ttttcctgcc cagcagttta ctacctctat
    35161 taaggctttg agaaaggaca agccaatctt gctttatgaa aatgtaagac ctcaatatcg
    35221 ggtcaaagca gtcaaaacat tacgtaaggc tggctatacg gacctttatg tcctaaaagc
    35281 gggactagat tattggaatg gtaaggttaa atagccttat agtccttttt gctgagctaa
    35341 cgtttgctgc tatgtgtcgg aacgttgcaa gcagcagctt atctaagctt gtcatgctag
    35401 tttcacagcc caaagtggct ggccgtataa acgcagctgc ttttagatgc cggtaggagc
    35461 ttttgtcagc ttctttaggg attgttttaa gtgatgtaga gaggccgttc tgagagaaag
    35521 ccttgtagtt agaaaaagag atgagaaagc taaggctctt gctgctgttg taagagttag
    35581 ctttcttttt cttttttgtg tggcgcattt aagggcttga aaacatttac aattccctca
    35641 gatcggtttt ttaaaaaaat ttgtgttata ctgttttagt taaaactatt tatgctacaa
    35701 gaggaaaaaa tgacaaaatt tagagaagat attcgtaacg ttgctattat tgcccacgtt
    35761 gaccatggga aaacaacgct cgttgatgaa ttactaaagc aatcccatac actagatgag
    35821 cgcaaagagc ttcaagaacg tgcgatggat tcaaatgacc ttgaaaaaga gcgtggtatt
    35881 accattcttg ctaaaaatac cgcagtagct tataacgatg ttcgtattaa tatcatggat
    35941 actcctgggc acgctgactt tggaggcgag gttgagcgta tcatgaaaat ggttgatggt
    36001 gttgtccttg ttgttgacgc ttacgaggga accatgcctc aaacacgctt tgtgctgaag
    36061 aaggccttag aacaaaattt aaccccaatc gttgtggtta ataagattga taagccatca
    36121 gctcgtccag ctgaggttgt tgatgaggtt cttgagcttt tcattgagct tggtgcagac
    36181 gatgatcagc tggagttccc tgttgtttac gcttcggcga tcaatggcac atcttcgttg
    36241 tcagatgatc ctgctgatca ggaaaaaaca atggctccga tttttgatac cattatcgat
    36301 catattccag cacctgttga taactcagct gagccccttc aattccaggt gtcacttctt
    36361 gattacaatg attttgtagg tcgtattggg atcggtcgtg tctttcgtgg gactgttaag
    36421 gttggagatc aggtgacgct ttcaaagctt gatggcacca ctaaaaattt ccgcgttact
    36481 aagctgtttg gcttcttcgg gcttgagcgc aaggagattc aagaggccaa ggctggtgac
    36541 ttgattgcag tttctggtat ggaggacatt ttcgttggtg agacgattac accaacggat
    36601 tgtgtggagg ctttgcctgt tcttcgcatt gatgagccga cacttcaaat gaccttcttg
    36661 gttaacaact ctccctttgc tggtcgtgaa ggcaaatggg taacctctcg taaggttgag
    36721 gagcgtttgc ttgtggagct tcaaacagat gtgtcccttc gtgttgagcc aacagaatca
    36781 ccagataaat ggattgtgtc aggtcgtggt gagctgcatc tatctatttt aattgagacc
    36841 atgcgtcgtg agggctatga gcttcaggta tcgcgtccag aggttatcat taaggaaatt
    36901 gatggtgtca agtgtgagcc ttttgaacgt gtacagattg acacaccaga ggaatatcaa
    36961 ggtgctatta tccaatcctt gtcagaacgt aagggggata tgcttgatat gcagatggtt
    37021 ggtaatggtc aaacgcgtct tatttttctc attcctgccc gcggcttgat tggttattcg
    37081 actgaatttt tatcaatgac acgtggctat ggtatcatga atcatacctt tgatcagtat
    37141 ctgccagtgg ttgctggtga gattggtgga cgccatcgtg gagcgctggt ttcgattgaa
    37201 aacggtaagg caacaaccta ctcaatcatg cgtattgaag agcgcggaac aatctttgtt
    37261 aacccaggaa ctgaggttta tgagggcatg attgttggtg aaaattctcg tgacaatgac
    37321 cttggggtta atatcacaac tgctaagcag atgaccaacg ttcgttcagc aacaaaggat
    37381 cagacagctg ttatcaaaac accacgtatt ctaacccttg aggaatctct tgaattcttg
    37441 aatgatgacg aatacatgga ggtaacgcca gaatcaatcc gcttgcgcaa gcaaattttg
    37501 aacaaagcag cgcgtgataa agctaataaa aagaaaaaat cagcagaata aaggctggtt
    37561 ggtctgagca tcacactccc ttgccgcttt aactagtaag ctaggttggc agaggattga
    37621 aaggagcttt ctgtgtttta tcttattatt gcagccttga ttacctctta ttacctgttt
    37681 atggcaccaa agagcgtccg taacacacta ggtatgattg gtttggttgg tttggttgcc
    37741 ctattgattg tgctagctgg cttaagtttt atcaaaatca tgcaaacgcc caaggaaatt
    37801 ttcgttggtc tagccatgat agtattgggc tactatgccc taagggacat tcaaaaaatc
    37861 cctaaaaaac caaagagtaa acattagcat caagcattga gtcaaatctt aatagggttt
    37921 gactttttct gtctttgtac tggccttatg cgctgctatc tgtaaaatct tgaaaaagca
    37981 gttaaataag ggtaaaatag tagtcaaata gacatagata gtgtggataa aaatgaagac
    38041 aataacggaa ttccaaaata aaaaggtatt gattcttggc ctggccaaat cgggcgaagc
    38101 agcagctagg cttttagccc ggttgggagc tattgtgaca gttaatgata gcaagccctt
    38161 tgaggaaaat cccgcagcac aggctcttct tgaggagggc ataagggtta tttgtggtag
    38221 ccaccccttg gagctgttag atgaagactt ttattgtatg gttaaaaacc cagggattcg
    38281 ctatgacaac ccgatggtgg tacgcgcctt agataaggct atttctattc taacagaggt
    38341 tgagctggct tatttggtat ctgaagcacc tatcattggt attacgggct caaatggtaa
    38401 aaccactaca accacaatga ttgctgatgt gctaaatgct gggaaccatt cagctctttt
    38461 ggctgggaat atcggctttc ctgcttcaga ggtggctcaa gctgctacag caaaggatat
    38521 actggtcatg gaattgtctt cctttcagct gctggggact gagcagtttc agccacatat
    38581 tgcagtcatt actaacctag tgcctactca tcttgattat catgggagtt ttgaggacta
    38641 tatagcggcc aagtggcgca ttcaacatcg aatgaccgat aaggattacc ttgtgttaaa
    38701 tgctgatcaa gagctggtaa aatcattggc tcaaaagact aaagcaagtc ctgtcttttt
    38761 ttctaccaaa gaaaaagttg atggtgctta tttggcagat gggtatcttt atttcaaaga
    38821 ggagaggctg atgtcagcag ctgagcttgg tgttcctgga aggcataaca ttgaaaatgc
    38881 tcttgccacc attgctgttg caaagctaag aggcatttct aatcaagtga tatcaaggac
    38941 tttgtctcac tttagggggg tgaagcaccg ccttcagtta gttggtacat tgaatcaagt
    39001 gaccttctac aatgacagca agtcaaccaa tatcttggct tgtcaaaaag ccttgtcggg
    39061 ctttgataat agcaaggtta tcctgattgc tggtggcttg gatcgtggca atgaatttga
    39121 tgagctggtg ccagacctcg ttggtcttaa aaagatgatt cttttagggg aatccgcaga
    39181 gcgtatgaag cgagctgcag acaaggcagg agtgtcctat cttgatgcca aagatgttgc
    39241 agctgccact aaaatagcct ttgagcaggc aaaggctggt gatattatct tgctgagccc
    39301 agccaatgct agctgggata tgtatccaag ctttgaaagc cgcggcgacg agtttttagc
    39361 agcctatgac gcgttaaaag gagaggctca atgaccaaga aaatcatttt taccggtggt
    39421 ggaacagctg gtcatgtcac tttaaacctt atcctcatac cgaagtttat caaagatggc
    39481 tgggaggttc actatattgg tgatgacaaa ggcattgagc atcaggagat caaaaagtca
    39541 ggtcttgatg tcacctttca tgctattgca actggaaaat taaggcgtta tttctcttgg
    39601 caaaacctgc ttgatatctt caaggtaggc tttggtgtca tgcaatcact ttttatcata
    39661 gctagactaa ggcctaaggc tctcttttca aagggaggct ttgtgtcggt tcctcctgtg
    39721 attgctgcaa ggcttttagg ggtgccggcc tttattcatg agtcggatct ttctatgggc
    39781 ttggctaata ggattgctta tcggtttgca acaacgatgt atacaacctt tgagcaagag
    39841 cagacactgg caaagctcaa gcatgttgga gcggttacca aggtgacagg tcctgggagt
    39901 cgatcggtga cttctaagca gcttgaagct gttttggagt attttgatcc taatttaaaa
    39961 acacttttgt ttattggagg ctccgcaggg gctagggtgt ttaaccgctt tatcactgac
    40021 catcctgagc taaaggaaga ctttaatatc atcaatatct ctggcgatcc tagcctaaat
    40081 gagcttagtt ggcatcttta ccgcgtggat tatgtgactg atctgtatca accgctcatg
    40141 gaaatggctg atctggtagt gactcgcgga ggctctaaca cactttttga attattagcg
    40201 atgagaaagc tccagcttat tatcccactt ggcaaagagg ccagtcgagg tgatcagctt
    40261 gagaatgctc attattttac aacaaggggc tatgctgagc aattattgga gcaggaattg
    40321 accctgcctc attttcaaga gaaagtgaga gaagtctttg ctaagcaatc ggactattta
    40381 tctgcaatga agagctctag cgagctccaa tcaccagaaa gcttttacca gcttttaagt
    40441 gccgacatta gctccgcgac aaaggaaaat taaatggcag ataagacaaa acattcagaa
    40501 gaaaaagccg ctttgaccga atggcaaaag cgtaatattg aatttctcaa caagaagcag
    40561 cagcaggctg agaaagacaa aaaactaaaa gaaaaattat taaatgagaa aatagcgcaa
    40621 gctcagggag aggcagcttc aaaggctgac caagaagata cagatgaagc tgaggagaaa
    40681 actgaggtaa gccaagcggg tactgatgag ggtgagccgc tgccagaagc atcagagcag
    40741 gaagtcccct ccccaaaaga caagccatta aaagtcccca aagaaaaaag tccaaagcag
    40801 caggcacttc aaaagggctg gcctgtattg ctggtgtcgt ttgtggtttt gtgcctgtcg
    40861 atttttatga tcacacccta tagtaaggtc aaggatttct ccgtcaaggg caataaaaaa
    40921 acaagcgttg aggacttagt tagagacagt gggatcaagt catctgatta ctggattact
    40981 ctattagcct ctccgggttc ttatgaaaat gcggttttaa aagccaatcc ctgggtgaaa
    41041 aaggtggctt tgcgttacgg ctttcccaat catttccgct ttgatgtgac agagtttgat
    41101 attattgcct acgctcaggt agctgaaggg tttcaactga tcctagaaaa tggcaagcga
    41161 gttgctgctg tcaagcaggc tgctttgcct aaatcctttt tgattttaaa tcttgagcat
    41221 gaaaaagaga ttcaagatgt cattaatcgc ttgaccaaaa tcccaagtga cctagtcaag
    41281 gctatcaaat cagtgtcatc ggccaattca cagacaacta aggatttgct gcttcttgaa
    41341 atgcacgatg gcaaccttat cagggtacct cggtcacagc ttgagctaaa gctgccttat
    41401 taccaaaaaa tcaagaagaa tcttgatact gctagcattg ttgatatgga ggttggtatc
    41461 tatacgacca ctgctgaaat tgaaaacatg cctgaggtgc cagcgtctgc tcaagcttct
    41521 caggcagata agcctgctga ggcttcacca gagcagggtg aagagcaggc cacacaggag
    41581 cagcctagcc ctgaaacacc tgctaatcct gaggccacaa atccctcagt cgcccagcct
    41641 actgagcagg caaatcaaca gtaatcgttt agggtaagag aagggggcaa aaaagcattt
    41701 aaggctctta aattaggccc ttgttgaacg gcaaaaaaac attaagttta tataacaaaa
    41761 aacgtaaaat ggtaacattt tacgtttttt tatgatataa tattccctga ataattctgc
    41821 tttttagcag tgtttttgaa tagtaaaagt ttggaaagta agtgaggtcg agtgaatggc
    41881 tagaaatggc ttttttactg gtttggacat tggaacaagc tcgataaagg ttttggtagc
    41941 agagtttatc tctggcgaga tgaatgttat tggtgtgagc aatgttccga gtactggcgt
    42001 aaaagatggc ataatcattg atatagaggc agcagccgct gctattaaaa ctgcagtaga
    42061 acaagctgaa gaaaaagcag gaatgacaat tgaaagggtc aatgttgggc tgccagcaaa
    42121 cctccttcaa attgagccga cacaaggcat gattcctgtt cctagcgaat caaaagaaat
    42181 caaagatgaa gacgttgata gcgttgttaa gtcagcacta actaagagca ttactccaga
    42241 gcgagaggtg atttccttag tccctgaaga gtttattgta gacggctttc agggcattcg
    42301 agatcctcgt ggcatgatgg ggatcaggct tgaaatgcgc ggtctgattt acactggacc
    42361 aagcacaatc ctgcataact taagaaagac agttgagcgt gctgggatta aggttgaaaa
    42421 catcatcatt tctcctttgg caatggctaa ggcggtgtta aatgaaggtg aacgtgaatt
    42481 tggtgctacg gtcattgaca tgggtggagg acaaaccacc gttgcctcaa tgcgagcaca
    42541 ggaattgcag tacaccaata tctatgcaga gggtggcgag tatatcacaa aggatatctc
    42601 taaggttctt aaaacgtcaa tgtcaattgc agaggccttg aagtacaatt ttgggcaggc
    42661 tgatatggca gaggcaagct tgactgacac tgttaaggtt gatgttgttg gcagtgatga
    42721 gccagttgag gtaacagagc gttacttatc agagattatc tcggctcgtg ttcgccatat
    42781 tctagatcgt gttaagcagg atttagaaag aggacgcctg cttgatttac ctggtggcat
    42841 tgtgctgata ggtggcggcg ccattatgcc gggcgtggtt gaggttgctc aagagatttt
    42901 tggaaccaat gttaagcttc atattccaaa tcaggttggt attcgtaacc caatgtttgc
    42961 caatgtcatt agcttggtcg agtacgttgg tatgatgtca gaggtggacg ttttagcgca
    43021 aaatgctgta tcaggcgagg aattgctaag acgtaagccg atcgacttta ctggccaaga
    43081 agcttacttg ccagactaca atgagactag gggatttgaa ccggctccta attatgagca
    43141 gcaagtgccc caagcagact acgagcctca agaacccgct gaaccaaagc aaaagatttc
    43201 agagcgtgtt cgtggcattt ttggaagtat gtttgattaa aagtaataaa gtgaggaaat
    43261 aaaatggcat tttcatttga tacggcatcc attcaaggtg caatcattaa ggtaatcggt
    43321 gttggtggag gtggcggaaa cgctattaac cgcatgattg atgagggggt tgcaggtgtt
    43381 gagtttatcg ctgcaaacac tgatattcag gcattaagct catcaaaagc agaaacagtt
    43441 gttcagcttg gtcctaaatt aactcgtggt cttggtgctg gaggtcagcc agaggttggt
    43501 cgtaaggcag cagaggaaag cgaagaggtt ctcacagaag ctttgactgg cgctgatatg
    43561 gtctttatca ctgctggtat gggtggaggc tctggaacag gagcagctcc agtgattgct
    43621 cgtatcgcta agagcctagg agccttgact gtggcagttg taacacgtcc atttggcttt
    43681 gaaggcaaca aacgcagtaa ttttgccatt gaggggattc aggagctaag agagcaggtt
    43741 gataccttat tgatcatctc aaataataac ctgcttgaaa ttgttgacaa aaagacacca
    43801 ttgcttgaag cgcttagcga agcagacaat gttttgcgtc agggtgtaca agggattact
    43861 gatctgatta caagccctgg cttgattaat cttgactttg ccgatgttaa gactgtgatg
    43921 gcaaataaag gcaatgcact tatggggatc ggtattggtt ctggtgagga acgtattgta
    43981 gaggcagctc gtaaggctat ctactcacca ttacttgaaa caacaattga cggtgctgaa
    44041 gatgttatcg ttaacgtgac aggtggactt gatatgaccc tcacagaggc tgaggaggca
    44101 tctgaaattg ttggtcaggc agcaggtcaa ggcgttaaca tctggctagg aacatcgatt
    44161 gatgactcta tgagagacga aattcgcgta acagttgttg caacaggtgt tcgtcaggat
    44221 aaggcggagc aagcctcagg atttcgtcag ccacgcacct acactcagtc taacgctcag
    44281 caggctgctg gagcacaata tgcttcagag caggtgagac agactgcgca gccaagcttt
    44341 gatcgtcgtt catcaagctt tgattttgat atgggtgaaa cacgtgagat gcctaagtct
    44401 cagcaagcta tgccagctca tggccacaat cataatcagg gctcagcttt tggaaattgg
    44461 gacttacgtc gagacaatat tgctcgtcca gcagaaggtg agcttgacaa tcaattgaac
    44521 atgtcaacct tctcatcaaa tgatgacatt gatgatgaat tagaaacacc accatttttc
    44581 aaaaatcgtt aatgatggat ttacaaaaaa ataaggatat tgtttttgaa aatattcgct
    44641 tagccactca ggcagccaac cggcctgaaa acagtgtgtc agttatcgct gtcacaaaat
    44701 atgtggacaa ggcagttgca ggtcagctga ttgatatggg gattgagcat atcgctgaga
    44761 accgtattga taagtttcta gataaatatg aagccttgaa agataggcaa gttacttggc
    44821 attttatcgg tactttacag cgtcgaaagg taaaggaagt gattaataag gttgattatt
    44881 ttcatgcctt agattcagta aaactggctt tagaaattga aaagagagct gaccaccctg
    44941 tgaagtgttt tctacaagtt aatatttctg aagaagaaag caagcatggt tttaagattg
    45001 ctgagcttga tgctgctatt gaggaaatca gcaagatgga aaagcttcat cttgtcggta
    45061 tcatgacaat ggcacctatt gatgccagtc agcaagagct tagaagcatt ttccaaaaag
    45121 caaatcaatt aagaaaaaac ttgcagtcaa aaaagagaaa gaatatgccg tttacagaat
    45181 tgagtatggg catgagtaac gattatccaa ttgctattca agaaggctca acctttgttc
    45241 gtattggaac atctttcttt cactaaatgg agaataagat ggcaattaaa gacgcattta
    45301 ataagatgat ttcttatttt gatactgatg gggtcagtga agtagaagag gagctatcct
    45361 ctaaaaagca agaagagcct gtgactaaat cacaacagac cagcagacct aatcagcagc
    45421 aacaagcagc tagagcgagt cagccccagc agcctaagca ggctagacct cagatgcaag
    45481 ctcagcaaag accacaatca caatcaagag ctgcctatgc tgagcgacca tatcaaggtc
    45541 aaagtcaagc acgtgtttct catgactaca atgacagaag ggcgacgtca gccccgtctg
    45601 cttctagtcg tcgtgagcaa tatcagcatg ctgctcatca agagcaaaca actattgcct
    45661 tgaagtatcc tcgtaagtat gaggacgccc aagaaattgt tgatcttttg attgttaatg
    45721 agtgtgtgct gatcgatttt caatacatgc tagatgctca ggcaaggcgt tgcctagatt
    45781 ttattgacgg tgctagtaag gtattgtatg gtactctgca aagggttggt tcttccatgt
    45841 atctgttgac cccatcaaat gtatctgtta atattgaaga gatgaatatc ccaaataatg
    45901 gccaagatat tggttttgat tttgatatga agagacgcta gtgtgatgat ttttatactg
    45961 ttgatacttc taaagctaat taaggtttat tcctatttgc tgctagtcta tgccttactg
    46021 tcttggtttc ctggagccta cgactcttgg cttggcaggc tggtcagcga tatagtagag
    46081 cctatcttaa aaccctttag atcattgaac ctacagtttg cgggcttgga ctttactatt
    46141 tacctagtga tgattggtct aaatgtttta agtgagatct tgataagagt gttgatctca
    46201 tgactgttca aacaatgctt tatcagcatt ttcagcctga tgaacaccca tttattgaaa
    46261 gaatgcttga cttgatcgct cgtgttgagg ctaattattt attagaggtt actgattttt
    46321 taaatccgcg agaggtcacg attttaaaag gcttagtcgc agcaaccaat ctgcagtgct
    46381 ttagctctac tgattattat cctagtgaat atggtcgtgt gattgttgct cctgactatt
    46441 attgtctaga taaggcagat tttgacttgg ctttgattga ggtgacctat aatgctaagt
    46501 ttaatcagct gacacatgca cagattttag gcaccttaat taatgaattg ggaatcaaaa
    46561 gagccttact tggcgatatt tttgttgaga taggtcatgc tcaggtcatg attaatcgac
    46621 agctgttaag ctattgttta ggaacgattg ctaaaatagc aaaagctagg gtcaagctca
    46681 aagaaattga tcttgatcag ctgttaaatc tgacagctaa tcagcaggtt ctgactgata
    46741 taatggtatc tagtctacgc gttgatcgct tgattgctac cgtattaaag caatctagaa
    46801 atcaggcgat aaggcttgtt gaagcaggca aggtcaaggt taactatcag cttgtcacta
    46861 aagcctctca gcctgtagct gttggtgatt taatcagcat tcgtggctac ggtaggttta
    46921 gcatactaac agacaatggc ttcacaaaaa atgggaaata taagctaaca cttagcaaaa
    46981 tgatgcgtaa ataaggagat ataatggcac ttacagcact agaaattaaa gataaaacgt
    47041 ttaagacaaa gtttcgtggc tacagtgaag aggaagtaaa tgaatttctt gagattgttg
    47101 tagacgatta tgaggctttg gttcgcaaaa atcgtgataa tgaagctaag ataagagagc
    47161 ttgaagaaaa gctgtcttac tttgatgaga tgaaggaatc attgagtcaa tctgttatcc
    47221 tagcccagga aacagctgaa aaagtgaaat cctcagcaaa tgctgaagca accaatttgg
    47281 tcagcaaggc aacctatgat gctcagcatt tacttgatga gtcaaaagca aaggctaacc
    47341 aactgttgcg cgacgcaaca gatgaagcaa agcgcgttgc tattgagaca gaggaattaa
    47401 agcgccagac acgcgttttc catcagcgct tggtttcagc tattgagtca cagctaagct
    47461 tatccaattc gcctgagtgg gacgaattgt tgcagccaac agctgtctac cttcaaaact
    47521 ctgatgcagc ctttaaagag gtggttaaaa ctgtccttaa tgaagatatt cctgaggctg
    47581 atgacagcaa ttcctttgat gcaacacgtc agtttacacc agaggagcta gaggagctgc
    47641 agcgtcgtgt tgaagaaagc aataaggagc tagaagccta tcaggtgcag cgagaagagc
    47701 aagctagcga gcctgaagtg aacctaagcg agacacagac ctttaaattg aatatttaat
    47761 cataagaaaa acaggattga atgcccaaaa tcacagcaag taggagatga tgagagtcct
    47821 atattccctg agcatgacaa ttatcatttt cttcaatcat cactgaatga cagtaagtga
    47881 cgagggaggc tcaccttacg agcaaagagg gaacagcaaa agggatttta ctgttctgaa
    47941 ttaaggtggt accacgagct ttcgtccttt ttgagacggg gctttttttg taattctgat
    48001 aagatattga ctaaaaggag tttgacaaga tgaaattaaa agaaacactt aacttaggca
    48061 aaacggcctt tccaatgcgt gccggtctac ccaacaagga gccacaatgg caaaaggctt
    48121 gggacgaggc tgagatttac aaaaaacgtc aagccttaaa tgaaggcaag cctgcctttc
    48181 acctgcacga tgggcctccc tatgcaaatg gtaatatcca tgtcggacat gcgctgaata
    48241 aaatttcaaa agacattatt gtacgtgcca aatctatgtc aggctatcaa gcgccttttg
    48301 ttccaggttg ggatactcat ggccttccta ttgagcaggt cttggctaag cagggggtta
    48361 agcgtaaaga gatggatctg gctgactatc ttgacatgtg tcgtcagtac gcgttaagtc
    48421 aggttgataa gcaaagagac gactttaagc gtctcggtgt atctgctgat tgggacaatc
    48481 cttatgttac cttagatcca agctttgaag ccgatcaaat tcgtgtcttt ggtgcgatgg
    48541 ctgataaggg ctacatttat cgtggggcaa agcctgtgta ttggtcatgg tcctctgaat
    48601 ctgctcttgc tgaggcagaa atcgaatacc atgatattga ttctacatcg ctttactatg
    48661 ctaatagggt taaagatggt aagggaatcc ttgatactga cacctatgtt gtggtttgga
    48721 cgaccacacc atttacggta acagcttctc gtggtctaac agttggacct gatatggatt
    48781 atgtggttgt tagacctgca ggttcagacc gtaactatgt ggtggcagaa ggactgctag
    48841 acagtctggc tgctaagttt gcttgggaat catttgagat tttggccaat cataagggct
    48901 ctgacttgga atacattgta accgagcacc cttgggacag tgaggttgat gagctagtca
    48961 ttcttggcga tcatgtgacg ctagattcag gtacaggtat cgttcataca gcacctggct
    49021 ttggtgaaga tgactacaac gttggtatga catatggact tgaggttgca gttacagttg
    49081 atgagcgtgg tttgatgatg gaaaatgcag gtcctgattt tcatggtcaa ttttatggca
    49141 aggtaactcc gattgttatt gaaaagcttg gagacctatt gcttgctcaa gaagtgatca
    49201 accactccta tccatttgat tggcgcacga aaaaaccaat tatttggcgg gctgttcctc
    49261 agtggtttgc ttctgtgtct gacttccgtc aagagattct agatgagatt gacaaaacaa
    49321 cattccaccc gacatgggga aagacacgac tctacaatat gattcgtgat cgtggcgatt
    49381 gggtgatctc tcgtcagcgt gcttggggtg ttccactgcc tattttctat gcagaggacg
    49441 gcacagccat tatgactaag gaggtaactg atcacgtcgc agatctgttc caagagcatg
    49501 ggtccattat ttggtggcaa aaagaggcta aggagctttt acctgaaggc ttcacacacc
    49561 caggctctcc aaatggggta tttaccaaag agacagatat catggacgtc tggtttgatt
    49621 cagggtcttc ttggaatggt gtgatgaatg ctcgtgatca tcttgcttat ccagctgacc
    49681 tctaccttga gggctccgat caatatcgtg gttggttcaa ctcatcactg attacctcag
    49741 ttgcggttaa tggtcatgca ccgtataagg ctatcctatc acagggcttt gtccttgatg
    49801 gtaagggtga aaaaatgtct aaatctaaag gaaatatcat ttcacctaat gatgttgcaa
    49861 agcaatatgg tgctgatatt ctccgtctct gggtagcttc tgttgataca gataatgatg
    49921 tgcgtgtgtc aatggatatc ctaggacagg tctctgaaac ctatcgtaaa atccgtaaca
    49981 cgcttcgctt cttgcttgct aatacatcag acttcaatcc acatacagat aaggtggctt
    50041 atgctgagct tgctgctgtt gataagtaca tgaccatcaa gtttaacaag ctagtaggag
    50101 ctatcaatac tgcctatgag cgttatgact tcatgacgat ttacaaggct gtggttaact
    50161 ttgtgacggt tgacttatct gctttctacc ttgattttgc caaagatgtg gtctacattg
    50221 aggctgctaa cagcctggca cgtcgtcgta tgcagactgt cttttatgat attttggtta
    50281 atatcactaa gctattgact ccgatccttc cacatacggc agaggaaatc tggtcatatt
    50341 tagagcatga gccagaagac tttgtacagc tatcagagct gccacaggct cagacttttg
    50401 ataatcaaga tactatccta gaggaatggg aagcctttat gacgcttcgg gcacaggcgc
    50461 aaaaggcttt ggaggaagca cgtcatgaca agattattgg taagtcctta gaagctcatc
    50521 tgacaattta tgcaagtcca gaggttaaga cactgttgac agctctagat agcgatattg
    50581 cactgctatt gattgtctct cagctaacca ttagtgagga gccagctcct gagaatgctg
    50641 tcagctttga tgatgttgcc tttacggtag ctcgtgcgca aggagaggtt tgtgagcgtt
    50701 cacgtcgtat cgatccaacg accagaatgc ggtcttataa tgcctttgtt tgtgaccaca
    50761 gtgcgaaaat tatcgaagaa aacttcccag aagcagtagc agaaggcttt gactcagctg
    50821 ctaattaagc aactaacagc tctgttcccg agttaaataa gcattggcgt gcttttgcca
    50881 atccagcagc aaggtgctag tcggtctggg cgtacctgcc ttactaggga ctctttgtgt
    50941 gggagctgat aagtgacctg ccttgagctt ggcaggtcta ggcttcttta taggttcacg
    51001 atttacgatt gactgggctt agagaagggc tagtcctgct aggcggcatt ggatatgaac
    51061 tgagtagtca tcatagctat aaaaaaacaa gcgcagactc acgtcagctt aatcgtgagc
    51121 ggcgcttgtt ttttcttggt tggggggtga aggcgaggag ctattaaagc taatattaag
    51181 cgatcaaaaa agcctagacc actagtcatg ttgtctaagc ttcagctgtt agagaggagc
    51241 tttctgagtg gaaggtagcc tatgctgata ggtgctgcct tagcctttta gcagtagtat
    51301 taaggctaga cagacgtctg gaaggaaatt tcaatcaaat tattggtgtg cagggttttt
    51361 gagtgacctg gaatcacaat agattggtca atcttacgct ttaagaaaaa ttcgcgaatc
    51421 acttcaagct cgtcctcttt gatggcacga tatttatttg aaatgagtag ctcataatgc
    51481 ttgggtgctt gcgtaaagat gacgtcagtg ttaccagctg agtaaacttc aacgaggtga
    51541 gcatctgtat tttgcagctg atttctgaca agctcggggt gactgctggt ggtattaata
    51601 agtctcataa atcttctcct gactattttt acttttatta tagcactatt tttaaattga
    51661 ttacggattt taatggtgct ttttctgcca ttcttcgacg ccccatctgt ggctatcacg
    51721 ctttaagact gttatggcgt ccgcaatagg aagaaaccaa gccagatggt taaagtcttc
    51781 caagggcttt gagatagctt ggaatgatgt cacctcgtac aggtaggcag gattatagta
    51841 gtaggtatcg cggtgacgag aatagaagta ttcgtctgct tgaccataat aataaccaat
    51901 atcagcagca aatcccagct cctcaactag ctcacgctcc agtgcctgta gctggctttc
    51961 accagcctct atttctcctc ctggcaaaaa ccaagcacca tttggagcct gcactaggat
    52021 aatctctgtt ttagccgagt taggaatcac tgcatagaca ccgtaacgtg cggtgtaatg
    52081 ctggtcatct atcttatcac caaatattgg aacggtcata tcgcttctcc tttgttttat
    52141 tatactaaat ttttggtcat tattctcata aaactgtaga tttatcaaaa atgtttcata
    52201 aaaaaatgct cgtcaaaaag agagaaaatg ctgtctgctt ttctctctgc ttttctctct
    52261 gctttttggt atgccctgtt agtccgcctg cttcgcctga gatttgacta caggcttgat
    52321 tataatgtgt ccattagagg tcaagacagc tcgcatgtct ttttctgctg ggtgctcaag
    52381 gtagaagtca gtaatggcgt cctcaatgta gtcctgaatg gtgcggcgca atggtcgtgc
    52441 tcccatctta ggatcatagc ctagctcaac gagcttttct ttgacctttt gggtgacatc
    52501 aaggcgaatg ttattgtgag caaggcggtg gttaacatca tcgagcatta aatgaacgat
    52561 atgtaaaaga ttgtccttgc ttagtggctg aaactcaata atgccatcaa agcgattcat
    52621 gaactcgggg ctaaagaaat gactgagctc tcctaaaaca gagtttgtcc gcccttctct
    52681 agcagcgcca aagcctactg aggcctctgt tttgccagtg ccagcatttg atgtcatgat
    52741 gataatagtg tccttaaagc taacggtacg tccttgtccg tcggttaatc gtccgtcatc
    52801 taggacctgt aaaaacatgt gcatgacatc agggtgagcc ttttcgatct catctaacaa
    52861 aatgagcgag taagggttgc ggcgcacctg ctctgttaac tgacctgcct cctcatagcc
    52921 gacgtagccg ggaggggcac cgacaagctt agccacagcg tgcttttcca tgtattcaga
    52981 catgtcaaag cgaatcatgt tatcagcaga gccaaaaagc tcaatggcta attgcttgga
    53041 aagctctgtt ttaccgacac cagttgggcc aacaaagagg aaggagccga taggacgatt
    53101 tggggctccc agtccaacac gattacgacg gatagctttt gcaattttat caacagcatc
    53161 gtcttgaccg ataacatgct ttttgagatc ggcggccaga ttgactagct gtgattgttc
    53221 cttttccttt aaatcaccaa ctggaatatt ggttttttgc tcaacgattg cttcgatggt
    53281 cttgtcagtg atgattggaa tatcctgctc atctagcttt tgagcctgca tttctttata
    53341 tttggcgatt tgatcgcgga aataggctgc tcgctcataa tcctcatcac gtgtggcttg
    53401 tgtcttgagg ttttcagcct caatcaaacg cttatcaatg tctttggggt caacaaagtt
    53461 aagggttagg ttcatctttg agccggcttc atctagcagg tcaatggcct tatcaggcaa
    53521 gaagcggtct tgaatatagc ggttggagag gttagcagct gcttcaatag ccgactggct
    53581 atatttgaca tggtgatagt cctcatattt gggttggatt ccttttagga tagtgattgt
    53641 ttcttcaacc gaaggctcgt ccaccttaac cggctgcatg cgtcgctcaa gggctgcgtc
    53701 cttttcgatg atgcgatatt cattgagagt ggtcgctccc actaattgaa gctcaccacg
    53761 agcaagtgct ggctttaaaa tatttcctgc gtccatgctg ccgtcaccaa ctgcaccagc
    53821 tcccacaatt tcatggattt catcaataaa tagaatcacg tcatggcgct tgcggatttc
    53881 ctccatgagc ttttgcatgc gctcttcaaa ttggccacga atacctgtcc cctgaacgag
    53941 gctaaccaca tcaaggcgaa tcacctgctt actctgtagc ttttgtggca catcgccatc
    54001 aacgattttt tgagcaaggc cttcaacgac agcagtctta ccaacacctg gttctccgat
    54061 taggacaggg ttatttttgg tacgacggtt gagaatctcg atcacgcgga taatctcatc
    54121 gtcacgtccg atgacaggat caatatcacc acgcttagcc atttcagtga tattaatgcc
    54181 gaattcctca agcaaacctt tgttagcctc ttgtgctggc tgtgtgtgat tgggacggta
    54241 gccattgtga cctccgccat tatggccgcc tgattgggta ggtggtgtat tgggcaattg
    54301 accgaaggct ctaaaattgt tcaggtcacc aaaaaagtca tcaaagaaag ggttttgaga
    54361 aggctgctgc gccttttggt tgccattata gcctcctaag ataggatttt tagggtctgt
    54421 tttcatgatt tggtagcaat tttgacagag gtcaatctgc ctttgctttc cgttaatgct
    54481 tgtataaaga tgaatggttg attcgtttaa attacagttt tgacaaagca tatcatacct
    54541 ccaaggggtt atctaaaaag tcaaggtcat ttagtcaaaa atggtcaaac tttatagtca
    54601 tattatagca ccttaggctt ggaaatcaag taaaaagctt cattattagc actttcaggt
    54661 atagagtgat aatctctata aatcttgctg ctcattggtt caaaaaagtc gtcaaagggg
    54721 ataaaataaa gagaaaatgg ctacttttct tgtttgtttt cgatgattta tgttaaaata
    54781 tatagggaca ataaacgaat aggagaaacg aaatggaatc acatttagtg agaatcatca
    54841 accgtctgga gctgatggta acagatggcg gtaatttaaa gagaaacttt gagcgagatg
    54901 gtgttgttgt tgcagaggtt gcatttgtca acgatcctga aaatggtcca gtctttattt
    54961 tacgtgatat tgaagcgcgt gagtcatatt catttgatag catcgatttg attgcgatgg
    55021 aaatttacga tttgttatat taagctattg atgatgacat gggcttgctg ggaggcaggt
    55081 cagacagagg acaagctggt gatttactgg tttgttttta ttatccctta aagcctcaag
    55141 acagctccag gaaaggcctt tctcctatgg tctttctagc cggtagggct tgatagtgat
    55201 taatagtgat ctgctctagc acggtcttga gcttttactg tcagaggctt gtgaccttag
    55261 ccactcgcag taaagggtac tggcccagta agcaaggtag gctaagtatc aatgtgaagt
    55321 tctaaccttg atcttagtga aatatttttg aggtgaatta agatgttaaa agtccttaga
    55381 atgctcattt ctaagggttt tgttgtgtct agctgttggt gtttgaaaga gcggtggtat
    55441 gataaagaga ggtcagaaaa gacctctctg atgtttgtga ttagctgtta gctattgcca
    55501 taggggaaag acacaatagc tagcttagct tttctttttc tttaggttta ggacgcctgc
    55561 gctagtgatg acgctaaggg ctgcaagggt gaagaatggg tgatttgtct cccctgtagc
    55621 tggtagcgtg ctcttttgag ctgctggtgc tgacttaggc gctggtgctt taggctgagc
    55681 tgatttttct ggagcctttg gtgcaggtgt cttttcaggt gcttttggag ctgatggttt
    55741 tgtatctttt ccttgatcac cctttggttt ttgctcgcct ttttcgccgc gttgtccttg
    55801 ctcgcctttt tcgccgcgtt gtccttgctc acctttttca ccgcgttgtc cttgctcacc
    55861 tttttcaccg cgttgtcctt gctcaccttt ttcaccgcgt tgtccttgct cacctttttc
    55921 accgcgttgt ccttgctcgc ctttttcacc gcgttgtcct tgctcacctt tttcaccgcg
    55981 ttgtccttgc tcaccttttt caccgcgttg tccttgctcg cctttttcgc cgcgttgtcc
    56041 ttgctcacct ttttcgccgc gttcgcctct gtcaccctta gggccggctg gtccttgttc
    56101 acctttagga cctgtttctc cggtttcgcc tttatctcca cgtggtccca taggcccaac
    56161 aggaccttgc tctccgcgtt cccctctagg tccggcaggc cccacaggtc cctgaggacc
    56221 acctttttta gcttgtagtt ctaagttttg taagtaggtt tgcatgaatt gtcttaatgt
    56281 atgtaggtat actcttactt cgccatctcc gagtccgtcc ctaattagtt cagctggatc
    56341 tggataggac tctaatcgcg tataatcttc agctcgggca tttccagctg ttcctaggct
    56401 ggccattgtt gctagggcaa tggctgctga gcagacgctg tacttgcgta ttgttttttt
    56461 catctttctc tcctttgatg atagtatcat tactttttca aaattctttc ccgaagaaga
    56521 gtttaacatg gtagcttgct atgagaaaca gctaggcgcc actttgtctc cgtagttttt
    56581 ttaattcaat gctgaatcgt ctgattttat cagagggtta ttgtttttaa aggcgaggag
    56641 ttgctttgct cagctagtct agcaagttca caggtcagct tatgtttctt atcaagcttg
    56701 tttgtttttg agaatatttt tcgataaaaa gatgttgtat taatattcat gttatagtat
    56761 aattatattc gttgccatga ctttatgaat gttaggagat aggaatggat tttacctttt
    56821 tacccaaata ctgggcttat ttcaattatg gtgtgcttgt aaccatgatg atttcagcct
    56881 gtgttgtctt ttttggcacg attataggtc ttttagtgac cctgataaaa cgcagtcata
    56941 tcaagccttt gtcttggctt gtcagtcttt atgtctggat ttttcgtgga acgccgatgg
    57001 tggtacagat catgattgct tttgcttggc tgcatttcaa cgatctgccc attgtaggct
    57061 ttggtgtgtt ggatttggat ttttcaagac tgcttcctgg tattattatt atttccttga
    57121 atagcggtgc ttacatatct gaaatcgtca gggctgggat tgaggcggtg ccaaaggggc
    57181 agctggaggc tgcttactct cttggtatcc gtcctaagaa cgccatgcgc tatgtgattt
    57241 tgcctcaggc ctttaagaat attttgccgg ccttgggcaa tgaattgatc accattatca
    57301 aggatagtgc cttgcttcag acgattggtg tgatggagct ttggaatgga gctcagtcgg
    57361 ttgtgacggc gacctatctg cctattacac ccttgctgtt tgcggccttt tattacttga
    57421 tgataacaac aatattgtcg caattattag gctgcttgga gcgcaagcta gcacagggag
    57481 ggagataaga tgactgagac agtgatttcg attcgtcagt tgcataagag ctttggcaag
    57541 catgaggtgc taaaaggaat agacctgacc attaatcagg gtgaggttgt ggtgattatt
    57601 gggccatctg gctcaggaaa gtccacgcta ttgcgcacga tgaatttgct tgaggtgcca
    57661 acaaagggac acatcagctt tgagggcgtc gatattacgg ataaggcaaa tgatattttc
    57721 aagatgcgtg agaagatggg catggttttt cagcagttta atctgtttcc caatatgaca
    57781 gtgctggaaa acatcaccct gtcacccatc aaaacaaaag gaatgtcaag ggctggcgcg
    57841 gagcagagag cttatgagct gcttgagcga gttgggctga gagataaggc tgctgcctat
    57901 ccggcaagct tatccggtgg tcagcagcag cgcattgcga ttgcgcgcgg cttggcaatg
    57961 gatcccgatg tgctgctctt tgatgagccg acctcagcgc ttgaccctga gatggtgggt
    58021 gaggttttgg ctgttatgca ggatttggca aaatcaggca tgacgatggt tattgtaacg
    58081 catgaaatgg gctttgccaa agaggtggcg gatcgcgtga tttttatgga cggtggtctt
    58141 gtgattgaag agggcagtcc agttcaggta tttgaagctc ctaaggagga gcggaccaag
    58201 gactttttga gcaaggtatt gtcatagctg gcgcagctaa agggcagcat gtcacctcaa
    58261 ggtctggcta ttagtcaatt ggctgtttgt tttgggcatt ttgtttgtaa aaggcttaga
    58321 aagtctggtt ggtgctgtag ccatatctgg ctttgctacg cttgggctgc tagctggtca
    58381 gtgggtatca tagtgattgg aggtgtggtc tctttattgg tcaacattgc tgtggcaggc
    58441 tagcacaggg gctttgcttg ttgtgctggg taaggggttt catttgcatg actgttaaca
    58501 ttgcttaatt gatgaattag gttgactttt gttttattgt ttgatactat tcaggtaagt
    58561 ctgtcattag aaagcgcttt gcttttttga tgatggaaat catgatcata tgatcacgtc
    58621 ttaggtaata tgttgttgtc aacatggtgg tctgaaagta ggaggataat atggactaca
    58681 aagctgttta tcaggagtgg ctgcacaatg attttttcaa tgaagaaatc aaggcagatt
    58741 tagaggcgat taagcatgat gaggctgaga ttcaagaccg tttttataag gtgcttgagt
    58801 ttgggacagc aggacttaga ggaaagctcg gtgctgggac caaccgtatg aatatttaca
    58861 tggttggtaa ggctgcgcag gctttagcta ataccattat tgatcatggg ccagaggcag
    58921 tctcacgcgg gattgccatc agctatgatg tgcgctataa gtctaaggaa ttcgcagaat
    58981 tgacctgctc gatcatggca gccaatggga tcaagtctta tatctacaag gggattcgtc
    59041 cgacaccgat gtgctcttat gcgattcgtg ccttgaactg tatctctggt gtcatgatta
    59101 ctgctagtca caatcctcag gcctacaatg gctacaaggc ttattgggaa gaggggtcac
    59161 agatcctaga tgacattgct aatcagatag cggttcatat ggacgctatt gagcgctttg
    59221 aggacgttaa gcagataccc tttgaggagg cattggcaag tggtctgacc agctatattg
    59281 atgatagtat agaggaggcc tataagaaag aggttttagg cttgaccatc aatgatactg
    59341 atattgataa gtcagtgcgt gtggtttata cacctttgaa tggcgttggt aatttgcctg
    59401 ttcgtgaggt attgaagaga cgaggctttg atcatgtctt tgtagtgccg gagcaggaaa
    59461 tgccagaccc agatttcaca acagttggtt atccaaatcc agaggtacca aaggcctttg
    59521 cttattcaga aagactaggg caagaagtag gagcagctat tctgattgcg actgatccgg
    59581 actgtgatcg tgtggcacta gaggttcgag ctgctgacgg tagttatgtc tttcttaatg
    59641 gtaataagat tggtgctttg ttgtcctact atatcttttc acagcgtcat gctaggcata
    59701 atcttcctga caatcctgtc cttgtcaaat caattgtaac aggggattta tcaaaagcta
    59761 ttgccgctaa atatgacgtt gaaacggttg agactcttac aggctttaaa aacatctgtg
    59821 gtaaggctaa tgactatgac atcacaaagg agaagaccta cgtctttggc tatgaggaaa
    59881 gcattggttt ttgttacggt acctttgtgc gtgataagga cgcggttagc gcctcaatga
    59941 tggtggtaga aatggctgcc tactacaagc aaaggggtca gtcactctta gatgtgcttc
    60001 aagacattta caaggaattt ggctattaca atgagcgtca ggtagcgcta gagctagagg
    60061 gtgttgaggg gcagaagcgt attgcacgta tcatggagga ctttagaaat gagcctattg
    60121 agcatgcagg tgctatgagc ttgaagacca ttgtagactt taaggacggc taccttgatt
    60181 ttccaaagca aaattgtttg aaatattatt ttgatgatgg gtcatggtat gcgctgagac
    60241 catctggaac agagcctaag atcaagcttt acatctatac tattggtgaa acagaggcag
    60301 acagcattgc taagctagac gctattgagt cagcttgtca agcaaagatg gacagtgtca
    60361 gctaattgtt caagctctgc aacagaaaat cagctaatca ataagcaaaa aggaaaagga
    60421 agtgacagtg cttccttttt tcgttataat agttaaaaaa ttagcaagga gtgcatatgg
    60481 tacagattat tgatgggaag gccctagcac agaaaatgca ggcagcattg gctaagaagg
    60541 tagagagctt aaaggcagaa aaaggaattg ttccaggcct tgttgtcatt ctggtaggag
    60601 acaaccctgc tagtcaggtt tacgtccgta ataaggaacg cgctgcctta gcagcaggct
    60661 ttaaaagtga aaccgttcgc ttgtctgatt cagtctgtca ggaagagttg atagagctca
    60721 ttgagcaata taatcaagat gatacgattc atggtatttt agtgcagctt cctcttccgc
    60781 accatattaa tgacaaaagc attatccttg ctattgatcc taaaaaggac gtcgatggct
    60841 ttcaccctat gaatacaggt catctgtggt caggtcgtcc gaatatggtc ccttgtactc
    60901 cggcagggat tatggagatg tttcatgact atggtatcga acttgaaggg aaaaatgctg
    60961 ttattgtcgg gcgctcaaat attgttggga agcctatggc gcagctactg ttggataaaa
    61021 atgctacggt aacgcttacc cattcgcgca cgcgccgact ggcagatatt tgtcgtcgtg
    61081 ctgatatctt gattgttgct attggtcagg ggcattttat cacaaaggag tttgttaaag
    61141 agggtgctgt tgttatagat gttggtatga atcgtgacgt caatgggcga ttgattggag
    61201 acgtcgcctt tgatgaggtg tcagagctgg ctagcatgat tactcctgtt ccgggtggtg
    61261 ttggaccgat gaccattact atgcttttgg agcaaaccta tcaagcagct ctaagaaggg
    61321 tgagtcaatg attatagatc aatcgtttgt tgctagggtt gttgttccgc ggcaggctga
    61381 ctcccataag gggagttacg gcagagtact gttagtaggt ggcttgtatc catacggtgg
    61441 tgctattatt atggtagcgc tggcctgtgt tcatagtggt gctggcctag taactgttgc
    61501 aactgataga gaaactattg ctgccttgca tagtcatttg ccagaggcga tggctattgc
    61561 ggtagatgat gaggaattac tgttatctca gctaggtatg gcagacctga ttttgattgg
    61621 tccggggctg tcggagaata gcagagcagc taggctgttt gaattggtcc ttgcacatgt
    61681 cgctgatcat caggtattgg tcattgatgg ctctgcctta aggcttttag cgaaaagggc
    61741 agctgatgtt aagcagctga ggtgccctct tgtgttaacg ccacaccaaa aggaatggga
    61801 ggcgctgtca ggtttagcga ttgatcagca gtatgatgct gccaaccaag cagctctcaa
    61861 gcattttcca agggctacga ttttggttgc taaaagctca gcaaccaaga tttatcatgg
    61921 caaccagatc taccggctaa gagtgggcgg accttatcag gctacaggtg gtatggggga
    61981 taccttggca ggtatgatag cagggatagc tgtccagttt ccagagtcaa gcttggtggc
    62041 taaggttgct tgtgcgacct atctgcactc tgcgattgct gatgagctgg caaagactgc
    62101 ctatgtggtt ttgccgactg ctattagcta tgagcttcct agatggctaa aggcaatcag
    62161 cacaggccag aagctaggtt gaggctgtgc tgcgaggtcg tttgggaaaa gcggttaatt
    62221 ggtaggcatg acagcagctg gtttcagtcg tttagctatt ttgagtttag agctgctagc
    62281 ttaagactgg gtgctgcttt atgattcaag gaagctatca ttggaaaaac ttgtgtcaag
    62341 ctgtagaagc cctagctggc ttcttttttt gtctcttttt tgctcactat ttatgtggaa
    62401 acatgatata attgcattag tatacagttg gagcagttag gcttcatgaa gtgaaaggta
    62461 aactgatggc agactattta tccgtcactc agctgacaaa atatttaaaa ttgaaatttg
    62521 atcgagaccc ttatctggag cgtgtctatc tcactggtca ggtatctaat ttcagaaaaa
    62581 gaccaaatca ccaatatttt tccttaaagg acgagggagc ggtgattcag gccaccatgt
    62641 gggcaggagc ttataaaaag cttggctttg atttagaaga gggcatgaag ctcaatgtgg
    62701 ttgggcgtat tcagctctat gagccaaatg gctcgtattc aatgatcatt gaaaaggctg
    62761 agccagacgg tattggtgct ttggcgctgc aatttgagca gctcaggcaa aagctggctg
    62821 gtgaaggctt ctttgatgag aggcataagc aggccctgcc gcaatttgtg acaaaggtag
    62881 gtattgtgac gagtccaagt ggggctgtga ttcgtgatat tatcacaacc atctcaaggc
    62941 gttttcctgg ggtgagtatt cttttgtttc caacaaaggt tcagggtgag ggggcagctc
    63001 aagaggttgc tgctaatatt actaaggcta accagcgtga ggatctggat ttgttgattg
    63061 ttggacgcgg cggtggctcg attgaggacc tgtgggcttt caatgaggaa atcgttgttc
    63121 aggctatttt tgagtctcgc ctgcctgtta tttccagcgt aggacatgag acagatacaa
    63181 ccttggctga ttttgtggct gatcgcagag ctgccacccc aaccgcagct gcagagctgg
    63241 cgacacctat tacaaaaaca gatattgtct cttggattgc tgagcagcag agccggtcct
    63301 atcaagcctg tctgcgctat atcagacaag ggcaggagcg ggtggataag ctttcttatt
    63361 ctgttatttt caggcagcca gagaggctct atgatgctta tagtcaacgc ttagataggc
    63421 ttacgacctc cttgatgacc acttttaaag agacattatc aggagctaag caggagcact
    63481 tgattttgga gcatcgttta gcctctgtca atgtacaggc aaggcttgag cgttatcagg
    63541 atcgtctggc aactgcgcat cgtctcttga tagccaatat gaccaatcaa tatgacagta
    63601 agctagcagg ctttgagcga gctcaagctg ccttgctgtc gcttgatacg agccgtatca
    63661 ttgcccgcgg ctatgccctg ttaaaaaagg acggtgtagt agctgcttgt gttaaggaca
    63721 ttaaaaaggg agatcatctt agtattatca tgcgtgatgg tcaattagaa gtagaggtag
    63781 aagatgtcaa cgaaaaaaat atttgaagag cgtttacaag aattagaggc cattgtgacg
    63841 aggctagaaa atggtgatgt gccactagaa gaggccatct ctgaatttca aaagggtatg
    63901 gtgctgtcca aggaccttca aaaaacctta caagcagctg aaaagacact tgttaaggtc
    63961 atgcaggcag atggcacaga gctagaaatg gatgcctaat ggataagcta acaagaatta
    64021 atgccacgat tcatcagtat tatgacaggc agtctactgt ttcagcagat ctggaggagg
    64081 ccattttata ttctgttgat ggtggaggaa agaggctccg tccactcatg ttattggagc
    64141 tgctagaggg ctttggtctt gccttgacag acgctcatta cgcggttgct gctgctgttg
    64201 agatgattca tacaggaagt ttgattcacg atgatttgcc tgctatggat aacgatgatt
    64261 accgtcgcgg gcgactaact agccacaagc aatttaatga agcaactgct attttggcag
    64321 gagatagtct ttttttggac ccttttgctc taatcgcagg ggcagatttg ccggctgacc
    64381 tgctggtgca attgattcag cagttttcct tagcgtcagg aacctttggc atggtcggtg
    64441 gtcagctctt ggacatgaag ggtgagcatc agctgctgga tattcaggag ctatctgata
    64501 ttcatgccaa taaaacaggg aaattgttga cccttccttt tgtggctgcg ggtatcatag
    64561 ctgagcagtc agcagacgtt ttgtcttgtc tgtgggaggc tggtaggctt gttggacagg
    64621 cctttcagat aagagatgat atattagacc ttacggctag ctttgctgat cttggcaaga
    64681 caccgcaaaa ggaccttgct gctgcaaaat caacctatcc gagtctgctt ggtttagagc
    64741 gctcaagggc tattttggag gagtctttga gtcaagcgct agctattttt agcagactag
    64801 aaagggaaga aggctttgag tctcaggcta ttatcaaaag gatcgagggg ttgcgactaa
    64861 atggctaaag aaagagtaga tgtgctagcc tatagacagg gactttttga aacgcgagaa
    64921 caggccaagc gcggtgtgat ggctgggcta gttatatcag ctataagtgg cttacgcttt
    64981 gataagcctg gtgaaaagat tgatgagggg atcgaactaa ggctcaaggg tgagaagctt
    65041 aagtatgtca gccgaggggg tctcaagctg gaaaaagcct tgcaggtctt tgggatctct
    65101 gtgcaggata aggtgacaat tgatattggt gcttcaacag gtggctttac agatgttatg
    65161 ctacaggcag gagctaggct ggtttacgct gttgatgttg gaaccaatca attggtctgg
    65221 aagctcaggc aggatagtcg tgttcgaagc atggagcagt acaattttcg ctatgcaaag
    65281 ctagcagatt tttcagaagg tcagccagcc tttgccagca ttgatgtgtc ctttatttct
    65341 cttagcctga tactgccgac attgcactgt attttgcagg aaggggcaga ggctgttgct
    65401 ctgatcaagc cacagtttga agcagggcgc gagcagattg gcaaaaaagg gattgtcaag
    65461 gatagactga ttcatgaaaa agtgattaag caggtggcag atactgctct taattgcgga
    65521 tttatcgtta aggggcttga tttttcgcct atccaaggtg gtcatggcaa tattgaattt
    65581 ttggctcatt tagtcaaggg aaagggctcc aaggctattg atgatcagct catacagagc
    65641 gttgttagca gtgcacataa ggaatttaaa cagcatgaaa aagagtgaac gattagattt
    65701 aataaaaaaa atggttttgt ctcatgagat tgagactcag catgagctat taaagctcct
    65761 agctgattat gggctagagc taactcaggc cactatttca agagacatga atgaaattgg
    65821 cattgtcaaa attccatctg gaactgggcg ttatgtctat ggcttgtcac aggatagtgg
    65881 caagcgggtg gtgcaaaggc ctgcctctat caaaaaaacg attttggaaa tgtctgaaaa
    65941 aacagcgggc ttggagcagc atattcacct caacgttgtt ccaggcaata gcaagctaat
    66001 caaacgttat ttgatgacag acttttcagg tcaattgttt agcctgattg cagatgatga
    66061 tagtttgctg ttgattgcaa aatcagaagc agacgctgat catatccgtc aggaattgtc
    66121 cctttggatg cagggattgg tctaaaaaat agagagaagc cgatgttatt agaaatttcc
    66181 attaagaatt ttgctatcat agaggaaatc tctttaaact ttgaaaacgg tatgaccgta
    66241 ctgactgggg agacaggggc aggaaagtcc attatcattg atgcgatgaa catgctgctg
    66301 ggtgcgcgcg caagcactga ggtgattcga catggtgctg ataaggcaga gattgagggc
    66361 ttcttttcgg ttgatgctaa tcctcattta gccgctgtgc tggcagaatc agggattagc
    66421 atggaagagg agttgattct tcgtcgtgat atttttgcta acggtcgtag cgtcagccgt
    66481 atcaatggtc aaatggtcac tgtcagcacc ctaaaaaaac ttgggcagtt tttagtggat
    66541 attcatggtc agcatgatca ggaggaattg atgcgtccac agctgcacca gcatattttg
    66601 gatagttttg gagatgaggc ctttgaccag ctcaagcagt cctatcagca gatttttgat
    66661 cgctataagg ctttgcgaag gcaggctctt gagaagcaaa aaaatgaaaa agaacatcag
    66721 gcgcgccttg acctgctggc ctttcagata ggggaaattg aggcagcaga tttggttaga
    66781 ggagaagatg acctgcttaa ccaagaaagg cagcgattgc tcaatcacaa aaagattgct
    66841 gataccttaa ccagtgccta cctttccttg gataatgagg acttttccag tctctcacag
    66901 gtccgctcta gcatgaatga gttgctgtct attgaggacc ttgccccaga gtatcagctt
    66961 atatcagctg gtgtgtcaga ggcttattat attcttgagg aggtcacaaa gcaattatct
    67021 gataccatcg accagcttga ttttgatgca ggcagattgc aggacattga gctgcgttta
    67081 gacagcatta atagtctgac aagaaaatat ggcggtggtg tgaatgatgt tttggactac
    67141 tatgccaata ttaccaagga ataccagtta ttaagcggag atgaccgttc ctctgatgag
    67201 ctagaaaggg aattaaaggt ccttgagaag caactggtga tgactgcctc acagctaagt
    67261 gacaagcgtc atgccctggc tctagagcta gaagccgaca tcaaagctga gctgagagag
    67321 ctttatatgg aaaaggcgga ctttaaggtc cactttacaa ggtcaaagtt taatcgagaa
    67381 ggcaatgaaa gcttagaatt ttatatctca accaatccag gtgagggctt taagccgctg
    67441 gttaaggttg cttcaggtgg tgagctttcc cgcttgatgc ttgctatcaa ggctgccatt
    67501 tctaaaaaag aggacaagac gagtattgtc tttgacgagg tggatactgg agtttcagga
    67561 cgtgtggccc aggccattgc taaaaaaata tataaaattg gcagctatgg tcaggtatta
    67621 gcgatttcgc atttgccaca ggtggttgct attgcagata accagtattt tatttccaag
    67681 gaaagcaagg aggagtcgac agtgtctaag gctaagctgt tgacacagga ggagcggatc
    67741 gaggagattg cgaagatgat tgcaggagct gatgtcacag agacagcaag aaatcaagcg
    67801 cgtgaattgc taggtaagga ctgagtatca tagcaaaagc agaacagtag ctttagagca
    67861 agcttgcctg ctgcacttgt cgctacatgt tcagaatgag ccacctgaaa ggcaagcaag
    67921 aaggctagct cttatgcgta tgctatcaga agctaagtct ttttgtctct tgcattggcg
    67981 agtgattgat tgataatatt atgataaata gaaggactaa aagaatactg actgaggagg
    68041 taaaatgctg aaaaaaagaa tgggcttggc tagtctgcta gtgttgatga cctttgtgta
    68101 tcagtgctgt tcagttactg ctgagcagta ttccgatact gaggttgagg tgctgcagat
    68161 tagcgaggag aaaagccaga tcatggaaaa tcaagaggcg cttaaagacc tcaccacgtc
    68221 gtctgatcag ctaaagaagg aagctttaaa gcctaaagag gcagctacca acaagagcaa
    68281 gcaagaggct tcgacagttt atttagctga ggacgatcct gtaaccattg atagctctga
    68341 cgaggaaagc aatcaagata tcatagcgga ttctgttcct gatttggtta ttaaaggtga
    68401 tcaggtggat gtatctgagg ttatggtctc tgtaaaggag gattcatcga aagttgctaa
    68461 gcaaagaact gacgcagcgc agcggtacag tatagccaag catcaattga cccaaaagct
    68521 tgaggccttt aatgcggcaa cggaccaatt gctgaccatg attgctaaaa aatctgattt
    68581 gactggtcag tattatgtgg ttgggcattc gttgggagaa atgctggctg ctcaaaatga
    68641 gaaaaagctt gctgagcaat tagtcatgca acaaaagcac aaaaaaggct taggctcatc
    68701 agtcactatt ttagacgaat taggacgtgt gatttctgac attagtggtc ataaaggcat
    68761 gcttcctttt aatcgtaaga tcagctttaa ggtacatcaa gtcagatacg atcttccact
    68821 aactggtgat cgaacagtgc tacctgccca gctggctggc ttactgcttt tactaatagg
    68881 tcttatgctg cctaaagtag ctaacaagaa aagctaagat atggtcttgg cttttttatc
    68941 ttttaagagg gtgagttttt gacagatgtt ttagctaaca ccaagagcta gataccagct
    69001 ttgctttatt tttaaaggag tgataaaata aagagacgat aaatgaggtt agaaatggaa
    69061 cttaagatgg gaactattaa aattgttgca gattcatcaa tgacgattga accagagcta
    69121 atcaaatctc ttgatattac ggttgtaccg ctttctgtca tgattgatag caagctgtat
    69181 tctgataatg agctaaaaga ggaagggcaa tttctacagc tgatgagagc tagtaagtca
    69241 ttgccaaaaa ctagtcagcc accggtaggg ctttttgcag atatttatga gcgattggtc
    69301 aaggaggggg cgacagctat tgttgccatt cacctctcac cagctctttc aggaacaatt
    69361 gaggcatcac gtcagggagc tgaaattgca gcagcaccag ttacggtatt ggactcaggc
    69421 tttacagatc aggctttgaa gtttcaggtg gttgaagcgg ctagactggc tcaagctggc
    69481 gctagccttg aggaaatcct tgaggcggta gaggatatta aacgaaagac agagctttat
    69541 ataggggtat cagcacttga gcacttggtt aaggggggac gaatcggtcg tgtgacaggc
    69601 ttgcttagct ccttgctgaa tattcgtgtg gtcatggaaa tgaaaaatga taccctgcaa
    69661 acacttgtta aaggacgcgg caataagacc tttactaaat ggctggatag ctatctagca
    69721 gaaaatagcc agcgacagat agctgaggtg gccatttcct atgctggtca gagggatttt
    69781 gctgatagcc tgaagaagac aatcgctacg gtctttgatg ggccaattac tgttttggag
    69841 actggctcaa tcattcaaac acatactggc gagggcgctt ttgcggtgat ggttagatat
    69901 gaataagcga gggtttttgg gaggccttat cttctttttc agtgtttttg ccttatcatt
    69961 tgtgatatta gctgtcctta ttccaaagtc tgacccacag ctgaagaaaa gtgattttct
    70021 aaaaaataag aagataagcc tcaattatat tgctattgga gactccttga cagagggagt
    70081 gggtgatctc accaaccaag gaggctttgt gcccttattg tctggtgatc ttggagacta
    70141 ctttaatgct accgttaata ctgaaaatta cggtgtttcc ggtaatacca gccagcaaat
    70201 tttaacgaga atgactgaga acaaggagat cacagagcag ctcaaaaaag ctaatctcat
    70261 gacattaacg gttggtggca atgatgtctt ggctgttatt cgcaagaact tagctaatct
    70321 taaggtatca agctttaaaa agccagcaag gcaataccaa gagcgcttac gcaaaatcct
    70381 tgatttggcc agaaaggata atcaggatct gccgatcttt gttttaggta tctacaatcc
    70441 tttttatttg aattttcagg agctaacaga aatgcagacg gtcattaatg actggaacaa
    70501 aaaaacacaa gaggttgttg atgactatga ccatgtttac tttgttccaa ttaatgatct
    70561 attgtacaaa ggagtagatg gtaaagaggg cattgtccag tcaacaggag agcaaacaac
    70621 gattgtgaat gatgctttgt tttcagggga tcattttcac cccaataaca caggctacca
    70681 aatcatgtca gacgcagtaa tggagacaat aagaaagaat ggaaaagaaa ttaaacctta
    70741 attggtggaa atgggctttt ttgctattat tggcttttaa tgcagccttt ttagcagtta
    70801 ttggaagtcg tattatacaa ataagagagc ctaagtctga gctgatcaat caaaaagcag
    70861 caaagaatat taaaataggg accttaacaa ccactaaaga gcaattaaat gaggcagtcg
    70921 ttagctacct aaaggatttt cagacggaaa aaatgaccta taaggtgtat gccacctcct
    70981 cgaccattct ctttgaagga acctatcagc tcttaggata tgaggtgccg ttatacattt
    71041 attttcagcc tcatcgctta accaatggtg cgatacagct gcaggttctc tccttttctg
    71101 tggggaccct ttctttgccg gaaaaggacg ttttgcaata cttgaaatcc agctataagc
    71161 tgccaaaatt cgttgaagtc ttacctaagc aatcggctat tattatcaat ctacagcaat
    71221 tggaaaatga tgccaacatc tatttaaagg ctcaaaagat tgatcttgtc aaggatgata
    71281 ttcgatttga catctataag aaatgagtct aactaacgtt taatacttga cctgtggctg
    71341 ttttttagat atgataatat ctgttaaagc gttaagctta ctaattattt ggaggattgt
    71401 taaatggcta acaaacaaga tttaatcgca aaggttgcag aagcaactga gcttacaaag
    71461 aaagattcag cagcagcagt tgacgctgtc ttttctgcaa tcgaagcttt tcttgctgaa
    71521 ggtgaaaagg tacaattaat tggttttggt aactttgagg ttcgtgaacg cgctgctcgt
    71581 aaaggtcgca acccacaaac tggtgaagaa attgaaattg cagcttcaaa ggttccagca
    71641 ttcaaggctg gtaaagctct taaggacgct gtaaaataat aaatcaaaaa aagccctatc
    71701 tcattaagct gtttagcctg tgagataggg ctttttccat taaggaagga gtcttgtttc
    71761 aataagtaat cttgtgtgat cgtctgaaag attagcgcca ataatttcta atgtgcactg
    71821 tcttgggaac aagagttcca tttcataagg ataaaatgag tagggctgta caaaagcagc
    71881 ctggctgcct tgagggacct gaattcttaa ttccactgag cgatgtggca tagcagcatt
    71941 tttgatggct gtagtactca taaagccttg ctttgtataa tgagtgcctg gcttgatcgc
    72001 tgataggatc tgcggatcaa aggtcttatc atggtagtaa cgagcgagtt cctcttcaga
    72061 agtgcccaat tctgttaaga atgtttcata aacatagcga tagacgatga tattccaagg
    72121 gatggttagc ttatgagtag cactatcaag taaggctaca gactgctgca gctgggcatc
    72181 caactggctg gtatctccca tcacctgttc tagggctagg ttaatagggc tggcagaggc
    72241 gtatgtatac tgatacatca tctttttttc tgcttctgta aaggctgttt gagacctcca
    72301 gcgattggtg ataatgtatt tggtaacatc aggctcacta aatttataat aaggcttaaa
    72361 gctattccca tagggctcaa aaacaactgt ttgtccttca tcataagact gtgccttgat
    72421 ggttgaaggc tgaacgacaa gcaacgataa gaaaaatgta aacaagcata gtgtacgaat
    72481 agctatcctt tgataagata actttgcgtt atgatgttga tgagtcattt agcttttcct
    72541 cctttacagt agtgccaaga gtgtcatcac ctaatgatga tgtctgttgc taacaggatt
    72601 agccttagtt gaaatgatta caaacttcct taatgtaaca aacataataa aaataaatta
    72661 tttttttatt atatattagt taagctcaga tgacaagcta tttgattttt ttctgagata
    72721 atgttacaag ggatttctaa caccaatgac taactcagat gaagggcttt ttcttggagg
    72781 attgcctata gttacaatag taggcaagac tggcagtcgc catgatacct attccaataa
    72841 cagcaaaggt tgctagatga acagaggctg gtatacaggt catgatggta gttgccagtg
    72901 gcattaagag aatagcagtt gtgacgattg agctaaagac tcgtcctagc aatgcctcag
    72961 gaactttttt ttgaacgata gaaaagaagt gaatgttaaa gattgttaaa aagcattcaa
    73021 accataaatt cccaagggca atcacaatga ctggaagctt caagagagcc atagctgtta
    73081 ttagaagcat ccctaggcca ctaaggccta gggataggag taagctttgc tgattatttt
    73141 taaagagctt gttagccata aaagctccta agatagcccc taaagctccc atcgaaagaa
    73201 gactagcata gcttgattgg ctgcctagca gctgattcga aaaaggaatt aaataattga
    73261 aagcagcaat aaagaaattc acaagagaag caataatcaa caaagaaaaa atgtcattgt
    73321 catggtagat gaattgcagc ccctccttaa tatctgttaa aagctgaagc ctattgcctt
    73381 ggctgctctg tttagtgatg tgcctttctt tgtccttgat tgtatataga catagaaagg
    73441 acaatagaaa gctaatgcta tctagagcca aggctgtttt gatgccaaag caatccatca
    73501 ctaaaaaagc aagcattggt gaggaaatac tgatgatttg agatacgatt tctagctgag
    73561 cattgaaatg aacaagtctt tctgtttcaa ctagtgtgac cacataggct cgaaaagcag
    73621 ttccagagaa ggcatacgat attgctaaaa gagcattaac agtgataagc ccataaagca
    73681 tgatagtagg gttagctatc agggctaaaa gtccgcagct gatagctccg atagcatctg
    73741 tccacaataa caattgtcgt cgtttataac gatcagcaat ggcgccaccg ataggattta
    73801 agatgagtga aataaggcct tcagctagct gataataacc caaatattgt cggccagttg
    73861 ctccgagtcc agcaatcccg ctgctgttgc tgtagtcgta aacagtattg cctattttgt
    73921 taatagctcg acttgcgagc agctggtagt cgtttttgcg catgataaaa cctccaaaag
    73981 attatgtggt tttattataa atcagttttt tagggtctta tgtttttttg caaataaggc
    74041 tagaggaggc tacaaatctt tcaaaatcct tttggtaatt gtgcgctagg tgaggacaat
    74101 ccaggctctc aaaaatggaa atagcagtag tcatatcctt aatgccagac aaacactgtc
    74161 ctctttggta gtcctctaag ccctttaaaa ataaaaagat ggttttttca tatagcttgg
    74221 tttcattatt gagtagggct agtatctgct tttgataata gcgcgcatag tcaagctgat
    74281 gtcggtggat acaggtttcc caaatattga gaagggtgat ggtaaccaaa tgcttattgg
    74341 ttgaaatgct ttcgtagtag gtatgattgt ttagaatttc ctttcccatt ttatctaata
    74401 agggaatatc aataaaaaga tagagatttc caattaaaat cagctcatag atatgccagc
    74461 tttcagtcct aaaaaggtag tcagtgacct catcaagata agccttagga aaaggaatgc
    74521 taggattgca tttacagata aagccttgga gtagaatgct gtttaaatag taacgattgg
    74581 tatcaggatc agcttggtgc tttgccaatt cctgcttttg cagctgcttg aatccctcaa
    74641 tatcgcgtgc atattccagc ttgatcagct gcgacatgaa ttgaatttgc tctgtctgtt
    74701 tgaagttggc agctatgtcc ataaattcgc tgatttccac ttgcatgctg tctaaagctg
    74761 ttaaaaactt tgttactgat agatcagatt cgccgcgttc aaagcgggat aactgagaca
    74821 aggacacgtc tttactggca agctgctgta aggtgatatt tctgttttgt ctaatgctgc
    74881 gaaatgcttt tcccaactga tgattagtca tattttttcc tcctctaatg agtatatcat
    74941 gtaaggcttc tgttgctgta ttttcccgta tgtgcaaacc ttgaaacttg tctgctgccg
    75001 ccacaaaggc atgaaaacat ttacactttt tgatagctat ttttatcatt gatgtagtct
    75061 ttttcgcaac atttgtacgg gatcatcaga ttaaaattaa gaaactgatg atgtgacact
    75121 gtaaacatgc taaaaatatg ttgaacaatg cctgtagctg gaaaatgggt acatgtattt
    75181 tcttcatgcc tgcgtcgtga cctgctgcta ttaaagcttg cttgaaaggg aaaaagagct
    75241 tataatagca gtgagaacat taaaaatgaa agtagagata tgccaataat tgttatcctt
    75301 ggacttgcta tcttttcggt ggttaaggtc attatttttc tatgctttta taaagcattt
    75361 gagaaaaaac aactaaagaa gctagaacag gatcaaaaag aaaccaagca ggcgattgac
    75421 caagaggagt caaaaaaagc ctttcccttt taacataaag ctagaaaaag tctgagacct
    75481 ttcgtctcag acttttttta aggcttatat tgtaattgac cacgaaaatc gtctagtgtc
    75541 tggtagccct tttcagccat aatgtcttgt agctccttag tgatacgctt aaaaatagct
    75601 ggaccttcct ggtgcagtgc tgttccaatt tgtaccatag ctgcgccgca taggatatgc
    75661 tcaaaggcat cacgtcctgt tttgacaccg cctgtgccaa tgatctgaat agaagagtta
    75721 agccgttggt aaaaggcatg aacattagcc agggcagttg gcttgatgta atcaccacca
    75781 ataccaccaa agccgttttt aggcttgatg acgacctgct catcatcaat aaccaagcca
    75841 ttgccaatgg aattaacaca gttggcaaag gctaaggggt attgattgaa aatggctgcg
    75901 gcttggtcaa aatggacaat atcaaaataa ggaggtagct tgatgcctag aggcttggtg
    75961 taataggaaa agatcttttt taggagctga tctgtggctt caaagtcata ggccagctga
    76021 ggcttacctg ggacattagg gcacgacagg tttagctcga caagtccttg ataatcagag
    76081 gcctgaatag cttttaggat agtctcggtt tcttcagcag acatgcccac aacagataaa
    76141 aagtggtgct tgcttgcttg atccttttgc atttctgtga caatatctaa ataatactgg
    76201 tagccatgat taggaagtcc cattgaattg attgagccaa gtgctgtatc tgcatagcga
    76261 ggctcagggt tgccctgtcg aggggctaga gtacctgttt ttgtcacaaa ggacccagcc
    76321 tcagaggcct caatggctag cagctcttcc ttggtcatgc aatacactcc agcagcgttc
    76381 atcaggcaat tattaaaggc aaatgtagcg atttttgtgg cagtagaaac catgttttcc
    76441 tccattttta gacaaatttt ttctattcta tcactagggc atgagaatag caaggcattt
    76501 ttgcaaaata cttgcttgaa ggctttcttt tgtgaggttt tagcgttttt catgatatta
    76561 acaaaatgat tttcaataaa gagaggaata gactagcttt tttgacctat tttttgtaaa
    76621 ataggagttg taaaaaggca agaagccttt aaacttaata aggagatatt aactaatggt
    76681 aaaattggtt ttcgctcgtc atggtgagtc agaatggaac aaagcaaacc ttttcactgg
    76741 ttgggctgac gttgatttgt ccgaaaaggg aacacagcag gctattgatg ctggaaaatt
    76801 gatcaaggaa gctggtattg catttgatct tgcctttaca tctgtgctta agcgtgctat
    76861 caagacaact aatcttgcac ttgagtattc tgatcagctt tgggtacctg ttgaaaaatc
    76921 atggcgcttg aacgagcgtc actatggtgg cttgactggt aaaaacaagg cagaagcagc
    76981 tgagcaattt ggtgatgagc aggttcatat ctggcgccgt tcatacgatg tgttgcctcc
    77041 tgatatggct aaagatgatg agcattcagc acatactgat cgtcgttacg ctcatcttga
    77101 tcattctgtt attccagatg cagaaaacct gaaggtaaca ctagagcgtg cccttccttt
    77161 ctgggaagat aagattgcac cagccttagt tgatggtaaa aatgtttttg ttggagcaca
    77221 tggtaactct attcgtgccc ttgtcaaaca catcaagcaa ttatcagatg acgagattat
    77281 gaatgtggaa atcccgaact tcccaccgct tgtgtttgaa tttgatgaca agctaaatct
    77341 tactgctgag tactacctcg gtggtgaata atgctgtgag gccagaccta gctctggctt
    77401 tttttgttat gtgataaaaa aggcgtttcc aacagaaatg tgatatgata gttaaaaagt
    77461 ggtaaaagaa gggaatctta tgaaagtaaa ggaacgccga gaagctatta cagataggtt
    77521 aagccaagca caagaagcca tctcagcaac tagcttagcc aaggcattgg gagttagtcg
    77581 tcaggtgatt gtcggagaca ttgccttact tagggcgcag cagcttgaca ttatttcaac
    77641 accaaaggga tatatcctgt caaatgcttt gtttagtcat cactattctg ctagaattgt
    77701 ttgccagcat ggacctgagc agacaaggca ggagttggag ttgatattag cacatgatgg
    77761 cattgtgacc aatgtggagg tagagcaccc tatttatggc atgctgacag caccgcttaa
    77821 cattaaaagc tcagctgata tcaataactt tattgaaaag ctcggagcct ctaaggcaga
    77881 attattgtcg tctttgacag agggtctgca cactcacctt ttgtcctgcc ctgatcagga
    77941 ggcatttgaa gagatcaaga gagatctagc agctgcaggc attctctatg gtgaacaata
    78001 atctgatagc agctggcttc acagggattt agtcttggct tgatagccaa tgtccctctt
    78061 ttgtcgtagg tgatagggac cgcaggacag ctcctagatg ctgaggccaa agtcttgtgg
    78121 ctgggcctca aatgaggtta aaagggaagg aagctgctat ggttatggtg aaagggctag
    78181 atttaccctt acttttttgc taggataatc ttttatgctg ttaggccgca gggcttggtg
    78241 ctgcaatggc tgagatgtgt ctgtcttttg tcttagcttt tggtgcttga gaagggctgg
    78301 gattgagctt atgctgtggt tgttttttga tttgctaggt gtcttgacat ctgtcgcgtt
    78361 tttggttata ctaacgacta gtaaaaggag atattatgac caaaaaacca acacaactga
    78421 ttgcctactc ttctattttg gtggcctttg ccatcttgat tccgatgata atgcccatta
    78481 agcttattat tggcccggct tcctttaccc tagctagtca tctgcccttg tttttagcca
    78541 tatttatatc cattccggta gcgatcttgg tggggatagg aacaggtctg ggctttttgc
    78601 tagcaggatt tcctatgatt attgttatgc gagccttctc acacgtgctt tttgcagcta
    78661 ttgcggcttt tatgctcaaa aggcagccta aatggctgga aacaccgtta agaacctttg
    78721 tttttgggat tatagcaaat gtgattcatg gcctagcaga gtttttagtg gtttatctga
    78781 tgacagcaac agcagcaact gatctttctt atttttggtc aatgctaatg cttgttggct
    78841 ttgggtcttt gctgcatggt atggtggatt tttatctagc cttatttatc tggcgcttct
    78901 taaggcagaa gggtcatcta tcagtgacaa gctaggattt ctgtgagtat ttatgtttta
    78961 gtagccaagg ctgttacagg ctgaggctct tttttctgaa agcgcttgca tttttttgaa
    79021 aaaatgctat actaaagagt gcgtttgtaa atatactaac aaaaggagat gtcatgaaaa
    79081 caccagaaca gatattagcc gcgacgatta cgattggtga gcataaggtt gcaaagcctt
    79141 ttttggctaa ggctatttta ggctttattg gcggtgcgat gattagtttg ggctacttat
    79201 tgtatgttag gattgcagct agtgggctgg agacctttgg cgctttttct agtattttgg
    79261 gtgcttgtgc ctttccgatt gggctgatca ttattttgat ggctggcggt gaattgatca
    79321 caggcaacat gatggcggtg tcggcagcct tttttgcaaa aaagattaag gccaaggact
    79381 tgatggccaa ttggctggtg attacccttt ttaatatttt gggagccttg ttcgttgcct
    79441 ttgtttttgg tcattttctg ggtctgacag ctactggcag ctttaaagaa gaggtcattg
    79501 aggtggccca tgccaagctt gctgcaactc ctctacaggc tattgtttca ggaattggct
    79561 gtaactggtt tgttggcctg gcgctttggc tgtgctatgg cgctagtgat gcgacaggta
    79621 agctccttgg aacctggttt cctgtgatga cctttgttgc ccttggtttt cagcatagtg
    79681 tggccaatgc ctttgttatt ccggcggcta tttttgaggg tggcgccagc tggatcgatt
    79741 ttgcgactaa ttttgctctc gtttatgtgg gcaatgtcct tggcggtgct atctttgtta
    79801 gtctctttta ttacaaggct tatgatcact ctaaggaagc ctgattagtg ctgttatatt
    79861 tttagactgg gagaccttat tctcagtctt atttttatat tttgtgataa aataggaaac
    79921 gacgtttaaa aaggaggagt tgataagcat ctaatatggc atcatggata aaaaagaaaa
    79981 aagcaagcat tcctaggcga attcatctcc tttttttggt gattgttttt ttgtttgttg
    80041 ccctgatttt gagattggca caaatgcaga tttatgagaa ggatttttac aaggcaaagc
    80101 tgacagcgtc aaccgtttac aaagtaaaaa gctctatgcc aaggggaacc atttttgacc
    80161 gtaatgggaa ggttctagtt tctaatcgta tcaaggacgt ggtaacctat acgagaagtc
    80221 ccaaggctag tgctaaggac attaaggctt tggctcatca gctagctgct tatattagct
    80281 atcctgaggc taaagtgaca gtcagagcca aaaaggatta ttatttggca gatccagagg
    80341 cttatgctaa gacggttcaa gccttacccc aaaaggacaa ggtggatcgc tttggtaata
    80401 aattagtcga agcacagata tatcaaaatg cggcagcctc tcttaaggaa acagacttga
    80461 cctattcaga ccaagagcta aaggttattg ctatttttaa ccaaatgaat gcagcagctg
    80521 tttttagcac tgtaaagctc aaaacatcag ccttatctga gcaggatatt gccatcatta
    80581 tggccaataa gtcaaaatta ccaggtattt cagttgggac agactgggag cgtcaggtgg
    80641 aggagacaag ccttgctgct attattggaa gggtctctag tgaggaagcc ggtcttccaa
    80701 aggaagaagc aaaggcttat cttaaaaagg gctattcgct taatgatcgt gttggaacct
    80761 cttatctgga aaagcaatac gaggaggtcc ttcaaggaaa gcatgaaatc agagaaatca
    80821 aaacgagcag atctggtgag gttatttcag ataaaatagt cgaaaagggt cagatggggc
    80881 ggaacctgaa gttgagcgtg ccacttgatt ttcaacaggg cgttgagcag atcttgaatc
    80941 agcacttcca gacagagctc aaaaatggtc aggctgctta ctcagaaggg atctatgctg
    81001 tggcgcttaa ccctaatacg ggagcgattt tagcgatggc aggtctatca cacaatccca
    81061 aaaccggtga gcttcaaaag gacgctttag ggactattac tgatgtgttt acacctgggt
    81121 ctgttgtcaa gggggcgacc ttggctgccg gctggcaggc tggagtgatt caggggaatc
    81181 aggtcttgat tgatcagccg attcaatttg gtggctccca gccgattaat tcttggttta
    81241 ccagcggtca gcaccctatt actgctagtc aggcgctgga atattcatca aatacttaca
    81301 tggttcaggt tgccttaaga atgatggggc aggattacgt gactggtatg accttggcca
    81361 atactggtat gaaggaaacc atgaaaaaat tgcgggcagc ctatgccgaa tttggcatgg
    81421 gagtggcaac tggcgttgat ttgcctggcg aatccagtgg ctacctcata gatcaatata
    81481 atactgcaaa tgttttgaca gaggcctttg gtcagtttga taactataca accatgcaac
    81541 tggcccaata tgtctcaact attgctaatg gcggcagtcg ccttgcgcct cacattgtag
    81601 aaggcattta tcaggataat gaccagtcag gaccaggtaa gctaagtaag gctattgaga
    81661 ctaccttgtt aaacaaggtg cacttagctg ctgatagttt agcgattatt caggacggtt
    81721 tttatcaggt ggtcaatagc ggtagtggct atgctacagg tagggctctt gcaggaggtc
    81781 ctgttaccat tagtgctaaa accggtaccg cagaaaccta tgctaaggat aaaaatggtc
    81841 aggctttatc tacctttaac ttgaatgttg ttgcctatgg tccgagtgct agtcctcaaa
    81901 ttgctgttgc tgtcatgtat cctcatgcga cagactctct agccaaggca catcaatacg
    81961 tggctaagga tatcattaat ttgtacatga agatgtataa aaaccaataa aggagaaacg
    82021 agtgctttac cctataccaa tcgcaaaatt aattgaaagc tattctaaat taccagggat
    82081 tggtgttaaa acagcgacaa gattggcttt ttacaccatt ggaatgtctg atgaggatgt
    82141 gaatgatttt gccaaaaatt tattagcagc taagcgagaa ttaacctatt gctctatctg
    82201 tggcaatttg acagatgatg atccctgcca tatttgcaca gatagcagtc gggataaaga
    82261 gatcatttta gttgttgagg attccaagga cgtttctgcc atggaaaaaa ttcaagaata
    82321 tcatggctat taccatgtgc tgcatggctt gatttctccc atgaatgggg ttggcccaga
    82381 tgacatcaat ctaaagagcc taatcacgcg tttgatggct ggagaggcaa cagaggtcat
    82441 tgttgcaacg aatgccacag cagatggaga ggcgactgcg atgtacatct cacgtctcct
    82501 aaagcctgct ggtatcaagg tgacgcgatt ggctagaggc ttggcagtag gatcagacat
    82561 tgaatatgct gatgaggtaa ccctgctgcg agcgattgaa aatcggacag aattatagct
    82621 tagcccattt tcagctctct gtcattagcc cttatgccat gtgataaggc cataaaggaa
    82681 ggcagatttt gtcagagtct tttgaaaagc aagctcgttt ttgttataat aagtggtagt
    82741 ctaattcaga tagggaaggt tatcaatgtc taaacaaacc ttaattttat tatacggagg
    82801 gcgttcggca gagcgtgaag tatcagtgct ttcagctgag agcgtgatga gagcagttga
    82861 ttacaccaaa ttttttgtta aaacctattt tatcagccag acaggtcagt ttatcaagac
    82921 acaggaattc tctagtcggc cgaccttaac agaaaggctg atgaccaacg acactattag
    82981 gctagagcag cagataaggc ctagtgatat ctacgaggag ggggctgttg tttttccagt
    83041 cttgcatggc cctatgggag aggacggttc tattcaaggc tttttagagg tgctaaaaat
    83101 gccttatgtg ggaactaata tcctctcatc aagtgttgca atggataaga ttaccaccaa
    83161 aagggtccta gagtcagctg gtatcccaca ggttgcttat accgtttata ttgaggggca
    83221 ggatttagac aggtgtctgg cagagactga ggcagtctta agctaccctg tgtttgttaa
    83281 gccggccaat atgggctcat ctgttggtat ttctaaggca gaatcagagg aggagttgcg
    83341 tgcagctatc ctgttggcct tgacgtatga cagtcgtatc ctgattgagc aaggggtttt
    83401 ggcaagagag attgaggttg gactgcttgg taataccgat gtcaaatcaa cccttccagg
    83461 agaggtagtc aagaatgttg acttttatga ttatcaggcc aaatacattg ataatgagat
    83521 cacaatggct attccggcag ctattgacga atcagctatg acaagcatgc gtacctacgc
    83581 agaaacagcc tttaaggcta ttggtgcttg tggcctgtcg cgttgtgatt tcttccttgg
    83641 tcaggacggt cagatctacc tcaatgaatt aaataccatg cctggcttta cgcagtggtc
    83701 catgtatccc ttgctctggg agcatatggg actgagctat gctgagctta ttgaggagct
    83761 agtcagatta gcacaggaaa tgtttgaaaa gcgtgaaggg catttaatat aagagacaaa
    83821 ggacggaagg agatatagca atcctctgtc ctttcgtttg gcctgattgg tagcgttttt
    83881 tggtcagaag cctttaaagc cctatcgtct acggttggct gtgccagctt tagcctgtct
    83941 atgaaggatc agcctgtagg cataaagtga aatagaaaga atattcctaa tatgttatgc
    84001 tata
//
LOCUS       DARYMD010000002        70484 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYMD010000002 DARYMD010000000
VERSION     DARYMD010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70484
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(757..843)
                     /locus_tag="TU818_000081"
     tRNA            complement(757..843)
                     /locus_tag="TU818_000081"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(807..809),aa:Ser,seq:gga)
     gene            complement(903..1538)
                     /gene="trmB"
                     /locus_tag="TU818_000082"
     CDS             complement(903..1538)
                     /gene="trmB"
                     /locus_tag="TU818_000082"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL0922953.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEVDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYQGNVMTEYEARFAKKGQIIYRLEATF"
     gene            complement(1538..2329)
                     /locus_tag="TU818_000083"
     CDS             complement(1538..2329)
                     /locus_tag="TU818_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL0922954.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            complement(2392..3426)
                     /locus_tag="TU818_000084"
     CDS             complement(2392..3426)
                     /locus_tag="TU818_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0922955.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLWLRLLLLSCLSLAFISNPYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            complement(3430..4155)
                     /locus_tag="TU818_000085"
     CDS             complement(3430..4155)
                     /locus_tag="TU818_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0922956.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            4692..5090
                     /locus_tag="TU818_000086"
     CDS             4692..5090
                     /locus_tag="TU818_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0922957.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTIFEKPQEVVI
                     TDGWQTISEKPQEVSTANEWQVSSEEAQESVPDKFSQNEDPSLWAVPDKFSQNEDPSL
                     WAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            5543..5962
                     /locus_tag="TU818_000087"
     CDS             5543..5962
                     /locus_tag="TU818_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL0922958.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQKATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYSQEDGIAIQYTTHEPDFPALAALAQQISQEISQ"
     gene            5959..6255
                     /locus_tag="TU818_000088"
     CDS             5959..6255
                     /locus_tag="TU818_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL0922959.1"
                     /translation="MTLKTMTTIGLTSVLAYQVYRKRHQIKETLVAMQTSKKAIQADV
                     DRIKANLAIIQKEARTLQAAGTELAYKWQAFNQEAQAHLTEIQQRMSKYQQETP"
     gene            complement(6425..7687)
                     /locus_tag="TU818_000089"
     CDS             complement(6425..7687)
                     /locus_tag="TU818_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL0922960.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSSGATTGTPAAP"
     gene            complement(7688..8215)
                     /locus_tag="TU818_000090"
     CDS             complement(7688..8215)
                     /locus_tag="TU818_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0922961.1"
                     /translation="MSEQVVTIEEAKASDASALITLIKEAADETDFITGTEDVIAATV
                     EVLECFLEASQESLTDICLLLKVGDILAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETTLDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            complement(8208..8651)
                     /gene="tsaE"
                     /locus_tag="TU818_000091"
     CDS             complement(8208..8651)
                     /gene="tsaE"
                     /locus_tag="TU818_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL0922962.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGV
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGGGVTVIEW
                     GELLAKGTLHDYLEILITKTETGRQVDYLAHGHRSEALLEELKHV"
     gene            complement(9017..10477)
                     /locus_tag="TU818_000092"
     CDS             complement(9017..10477)
                     /locus_tag="TU818_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL0922963.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDVDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            10736..11547
                     /locus_tag="TU818_000093"
                     /pseudo
     CDS             10736..11547
                     /locus_tag="TU818_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            11899..12891
                     /gene="manX"
                     /locus_tag="TU818_000094"
     CDS             11899..12891
                     /gene="manX"
                     /locus_tag="TU818_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL0922964.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSIAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
     gene            13062..13871
                     /locus_tag="TU818_000095"
     CDS             13062..13871
                     /locus_tag="TU818_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL0922965.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            13887..14798
                     /locus_tag="TU818_000096"
     CDS             13887..14798
                     /locus_tag="TU818_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL0922966.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            14932..15315
                     /locus_tag="TU818_000097"
     CDS             14932..15315
                     /locus_tag="TU818_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL0922967.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(15636..16688)
                     /locus_tag="TU818_000098"
     CDS             complement(15636..16688)
                     /locus_tag="TU818_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL0922968.1"
                     /translation="MTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLLFALFG
                     FPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQNLLKWVDKKIPFAD"
     gene            17288..18565
                     /gene="serS"
                     /locus_tag="TU818_000099"
     CDS             17288..18565
                     /gene="serS"
                     /locus_tag="TU818_000099"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL0922969.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITGIIT
                     VLPNTPHDSVPIGADEEDNVEIHRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLEVIKPR"
     gene            complement(18797..19567)
                     /locus_tag="TU818_000100"
     CDS             complement(18797..19567)
                     /locus_tag="TU818_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL0922970.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYF
                     SSEIVEMIKSHLIDEITQLQAKPLEELLDQRYQRFRKY"
     gene            complement(19564..20430)
                     /locus_tag="TU818_000101"
     CDS             complement(19564..20430)
                     /locus_tag="TU818_000101"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL0922971.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAIKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            complement(20439..21803)
                     /gene="accC"
                     /locus_tag="TU818_000102"
     CDS             complement(20439..21803)
                     /gene="accC"
                     /locus_tag="TU818_000102"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL0922972.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADREALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSGAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEIARQIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDSQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRIDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            complement(21837..22259)
                     /gene="fabZ"
                     /locus_tag="TU818_000103"
     CDS             complement(21837..22259)
                     /gene="fabZ"
                     /locus_tag="TU818_000103"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL0922973.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            complement(22256..22729)
                     /locus_tag="TU818_000104"
     CDS             complement(22256..22729)
                     /locus_tag="TU818_000104"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL0922974.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            complement(22731..23963)
                     /gene="fabF"
                     /locus_tag="TU818_000105"
     CDS             complement(22731..23963)
                     /gene="fabF"
                     /locus_tag="TU818_000105"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL0922975.1"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAMSN
                     TFGFGGHNAVLAFKRWED"
     gene            complement(23979..24713)
                     /gene="fabG"
                     /locus_tag="TU818_000106"
     CDS             complement(23979..24713)
                     /gene="fabG"
                     /locus_tag="TU818_000106"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL0922976.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKINLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILNQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            complement(24730..25650)
                     /gene="fabD"
                     /locus_tag="TU818_000107"
     CDS             complement(24730..25650)
                     /gene="fabD"
                     /locus_tag="TU818_000107"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL0922977.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQYAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            complement(25663..26649)
                     /gene="fabK"
                     /locus_tag="TU818_000108"
     CDS             complement(25663..26649)
                     /gene="fabK"
                     /locus_tag="TU818_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL0922978.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVIN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            complement(26844..27068)
                     /locus_tag="TU818_000109"
     CDS             complement(26844..27068)
                     /locus_tag="TU818_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL0922979.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            complement(27126..28100)
                     /locus_tag="TU818_000110"
     CDS             complement(27126..28100)
                     /locus_tag="TU818_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL0922980.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGAQGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            complement(28100..28534)
                     /locus_tag="TU818_000111"
     CDS             complement(28100..28534)
                     /locus_tag="TU818_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL0922981.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            complement(28614..29405)
                     /locus_tag="TU818_000112"
     CDS             complement(28614..29405)
                     /locus_tag="TU818_000112"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL0922982.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVRIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFRGK"
     gene            complement(29725..30861)
                     /gene="dnaJ"
                     /locus_tag="TU818_000113"
     CDS             complement(29725..30861)
                     /gene="dnaJ"
                     /locus_tag="TU818_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL0922983.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            complement(31018..32847)
                     /gene="dnaK"
                     /locus_tag="TU818_000114"
     CDS             complement(31018..32847)
                     /gene="dnaK"
                     /locus_tag="TU818_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL0922984.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQTALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            complement(33252..33821)
                     /gene="grpE"
                     /locus_tag="TU818_000115"
     CDS             complement(33252..33821)
                     /gene="grpE"
                     /locus_tag="TU818_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL0922985.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSAELIADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(33866..34900)
                     /gene="hrcA"
                     /locus_tag="TU818_000116"
     CDS             complement(33866..34900)
                     /gene="hrcA"
                     /locus_tag="TU818_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL0922986.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSLIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDLYQLVKAFDFEAFKLE
                     DVLLRASQMLSDTTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLSLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            complement(35350..35922)
                     /locus_tag="TU818_000117"
     CDS             complement(35350..35922)
                     /locus_tag="TU818_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0922987.1"
                     /translation="MRKRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     RQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQAASKHKTAYAIYRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGYKKPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            complement(35919..36662)
                     /locus_tag="TU818_000118"
     CDS             complement(35919..36662)
                     /locus_tag="TU818_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL0922988.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGVYLFIKPEKQAVGPKANQTVPAP
                     KAAKQAKKTTDLPKVSTTDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASALYITAHSLSLEEYLTRLKEKK"
     gene            complement(36652..37359)
                     /locus_tag="TU818_000119"
     CDS             complement(36652..37359)
                     /locus_tag="TU818_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL0922989.1"
                     /translation="MTKTRLYIVRHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRKSENEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            complement(37434..38771)
                     /locus_tag="TU818_000120"
     CDS             complement(37434..38771)
                     /locus_tag="TU818_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL0922990.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLSLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEIGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEIVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            complement(38786..39052)
                     /locus_tag="TU818_000121"
     CDS             complement(38786..39052)
                     /locus_tag="TU818_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL0922991.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            complement(39316..40431)
                     /locus_tag="TU818_000122"
     CDS             complement(39316..40431)
                     /locus_tag="TU818_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL0922992.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQAIPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRGGKRGYGYSYNPD"
     gene            complement(40628..40867)
                     /locus_tag="TU818_000123"
     CDS             complement(40628..40867)
                     /locus_tag="TU818_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL0922993.1"
                     /translation="MVWSLIVGAIIGMVAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
     gene            complement(40918..41862)
                     /locus_tag="TU818_000124"
     CDS             complement(40918..41862)
                     /locus_tag="TU818_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL0922994.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSAMAYVRQREAVISLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAVGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVCFAIILMKEIFHPIDL
                     LGMALILIAVLVISLRDLLLTKRKKQLALNIKRPPSSD"
     gene            complement(42091..43530)
                     /gene="gatB"
                     /locus_tag="TU818_000125"
     CDS             complement(42091..43530)
                     /gene="gatB"
                     /locus_tag="TU818_000125"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL0922995.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPADRRASYINALGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDPKQVSNWLQGEMAQFLNAEGKTIDQIALTPENLVEMIAIITDGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            complement(43530..44996)
                     /gene="gatA"
                     /locus_tag="TU818_000126"
     CDS             complement(43530..44996)
                     /gene="gatA"
                     /locus_tag="TU818_000126"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL0922996.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIACEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTIKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQVAVAFEATTDYHKQQPMIFGGDR"
     gene            complement(44996..45298)
                     /gene="gatC"
                     /locus_tag="TU818_000127"
     CDS             complement(44996..45298)
                     /gene="gatC"
                     /locus_tag="TU818_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL0922997.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGVAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            complement(45772..46329)
                     /locus_tag="TU818_000128"
     CDS             complement(45772..46329)
                     /locus_tag="TU818_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL0922998.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     STENHQWALNHCRTVLGAKLLDRLS"
     gene            complement(46946..47728)
                     /gene="codY"
                     /locus_tag="TU818_000129"
     CDS             complement(46946..47728)
                     /gene="codY"
                     /locus_tag="TU818_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL0922999.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PIESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTVVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            complement(47900..49114)
                     /locus_tag="TU818_000130"
     CDS             complement(47900..49114)
                     /locus_tag="TU818_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL0923000.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITHVLKQYKR"
     gene            49401..49853
                     /locus_tag="TU818_000131"
     CDS             49401..49853
                     /locus_tag="TU818_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL0923001.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDT
                     RALQSVATFDSYIYDKLEQEAKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIP
                     DKEEVDLIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
     gene            complement(50139..51527)
                     /locus_tag="TU818_000132"
     CDS             complement(50139..51527)
                     /locus_tag="TU818_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0923002.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQRAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMVSSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKERFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            51599..52564
                     /locus_tag="TU818_000133"
     CDS             51599..52564
                     /locus_tag="TU818_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL0923003.1"
                     /translation="MKEILVLHTGGTISMQADEAGKVSPNQNNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGVVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYR
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(52684..54699)
                     /gene="recG"
                     /locus_tag="TU818_000134"
     CDS             complement(52684..54699)
                     /gene="recG"
                     /locus_tag="TU818_000134"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL0923004.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDAVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHRQLDSVL
                     AWVKTELAKGTQAYVISPLIEESETLDLKNAVALEAELKDYFKASASVALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVAAEIVAAKDWQLDPRWAPILANLRVADQFD"
     gene            complement(55063..56517)
                     /locus_tag="TU818_000135"
     CDS             complement(55063..56517)
                     /locus_tag="TU818_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923005.1"
                     /translation="MEGLGGTDLDICDDSLHGSPVIKAKQLQFSYTNRRQTACELRDC
                     QIEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLKVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLERVLSPKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKQLEVKAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVTLPAKDRLSITSLVLQDVGLQLFSETVEKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVS
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLSR"
     gene            complement(56454..57134)
                     /locus_tag="TU818_000136"
     CDS             complement(56454..57134)
                     /locus_tag="TU818_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL0923006.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLALSVLPLHVLPAYLFRLLSFAAVAGQLLYPSVLAALIFVKTTT
                     AYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQP
                     RRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIFV
                     TIAYMVLQ"
     gene            complement(57131..57724)
                     /locus_tag="TU818_000137"
     CDS             complement(57131..57724)
                     /locus_tag="TU818_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL0923007.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYQSRLVNLLSYLVFAFVNSGPIILMWLLKDAYIQSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            complement(57705..59387)
                     /locus_tag="TU818_000138"
     CDS             complement(57705..59387)
                     /locus_tag="TU818_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923008.1"
                     /translation="MVKSDYSTYRLVLRLLAMMKHLLAWIALAVMFAVLGFVLTVGIP
                     TSLAYLGLEVMAGHAITFKWLYLFVAMALLRGLVRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKIIMKWYNW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACDEGLDTLVRGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            complement(59380..61143)
                     /locus_tag="TU818_000139"
     CDS             complement(59380..61143)
                     /locus_tag="TU818_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL0923009.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTEADVLTVASQGIDSLDTYYSYYLSLAMLTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADERYEESFVNKAEAFRKATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQD
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVTIDLASKQAINQEILYVSDQSTLLNMSIYENLAMAAQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKQAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQVELEANLYG"
     gene            complement(61189..61971)
                     /locus_tag="TU818_000140"
     CDS             complement(61189..61971)
                     /locus_tag="TU818_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923010.1"
                     /translation="MSHEQGLIRVEDLSFTYRDRPILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAQKVAVVHQDNQAVADLLVGDLV
                     AVASQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILALIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            complement(61968..62990)
                     /locus_tag="TU818_000141"
     CDS             complement(61968..62990)
                     /locus_tag="TU818_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL0923011.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMVLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFNGLFVAYDSEVALIYDLRFPRIVIALLAGAGIATSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDVI"
     gene            complement(62992..63876)
                     /gene="isdE"
                     /locus_tag="TU818_000142"
     CDS             complement(62992..63876)
                     /gene="isdE"
                     /locus_tag="TU818_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL0923012.1"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPRAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVK"
     gene            complement(63860..64765)
                     /locus_tag="TU818_000143"
     CDS             complement(63860..64765)
                     /locus_tag="TU818_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL0923013.1"
                     /translation="MKIINEEHMIKRLFKKLMGGLVVLLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYSVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSELQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSSPKKQSNPSKKGQAVGLSTSLDKSKQESSQKPVNNPLPVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            complement(64994..68745)
                     /locus_tag="TU818_000144"
                     /pseudo
     CDS             complement(64994..68745)
                     /locus_tag="TU818_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
     gene            complement(68947..70362)
                     /locus_tag="TU818_000145"
     CDS             complement(68947..70362)
                     /locus_tag="TU818_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0923014.1"
                     /translation="MRKNKLLRMIMLMTLLVPHLETARVLAEDTGAEASQVPATANEA
                     AIAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGSASGSTGQSTP
                     TSPAASPQPAPEVATQASQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
BASE COUNT        20395 a        16879 c        13784 g        19426 t
ORIGIN      
        1 ctatttttaa agacagcatt agttaatgat ataataaaag ctgtaatctc cctcattata
       61 tcataaaaac gatttcaaaa acagacttgt atttcaagtg acatttgata tacttgaaga
      121 tgggaatact gcttgagtgg aggcattgta ggtctagttc aacgtaaagc agcagctgaa
      181 atcgcaaaac taatacttaa agtggggatc aagaatgtag cccctgctgc agctgcagca
      241 tcattaattt ggagctttgg aagatgcatg tggttttaat gtcaaaaaga tatagtattt
      301 gtataacatt tcttgttatt atttcgcgat tcgtttggtt tgcccttaca ggaagaagtc
      361 ctttttatga ctttattggg actatatttt taggagtagt ggttttacta attagtcaaa
      421 aagtattgaa aaaattaaag tgataaaatt attaacccga caatagcgaa gcagaatgtg
      481 atattattga tatgttccat aagatacttt ctaatgagat tgttagtgct tctcatgata
      541 agtcttatgg gacttttttg tactcaaaaa gccctatcat ttccatactg gataaatcca
      601 ctacagaaat gatagagcct aaaatatatg ttcaccaatt ggataagtta aaagaaaaaa
      661 atgaccatca ggtcaaaagc atttttcaaa atctcaaatt tgacgggtga aaaacaggcg
      721 aagactccga aacccttgat ataccaatag gataaaagga gaggagggga ttcgaacccc
      781 cgagccccgt taaggactac acgctttcca agcgtgcgca ctcggccact atgcgacctc
      841 tccaagtaaa aggctgatca actcaacctc agtagtgtat catatttttg tcaaaatagc
      901 tactagaatg ttgcttctag gcggtaaata atctgtccct ttttagcaaa tctagcctca
      961 tactcagtca tcacatttcc ttgataatca ctagcatgta aatccagcca gacctgcttg
     1021 agggtcatac cgtactgtga aaagctcgct aggctatact caaataagcc acgattatct
     1081 gttttaaaat gaatttcacc attttccggc aaaatctgct tataagtgtc taaaaaggat
     1141 ttgtaggtta gtcgacgctt ttcatgcctg cttttgggcc aaggatctga aaaattcaaa
     1201 tacatcatat caacctcacc ggcatcgaaa taattggtca ggcttgaccc atcaacccgc
     1261 aagagcctaa cattaggagc ctgagaggct aggaccttat ctaaagcata gcttagcact
     1321 gatagctgaa tgtcaatgcc aatatagttg atctctgggt ttttcaacgc catacctgtg
     1381 ataaaggctc ccttgcctga gccaacctca atatggatcg gatgatcatt accaaagacc
     1441 tcacaccagc gccccttagc agcctccggc tctaaaatga catagtgagg attgttttcc
     1501 aagtgctcct gcgcaccctt tcgttttcta actcgcatta tttctttcta aacatttctc
     1561 taaattttct aagagcgtaa atctcttgat tgacatgctc catatctctc ttatcaaagc
     1621 accttaaaat ctgagttaga taagagaatt gagcatacca aataatcttt tgcatgacct
     1681 tatcattatt tttatagcca taataggata gccagtctgc ccatcgcgac cgaggaatat
     1741 agtggcttag caaataagcc acatcataca ttcgatctgt taggcgcaca caatcccagt
     1801 ccaccaaaaa aatcatgcca ctggtggtaa tcacccagtt gctatgcttg atatcaccat
     1861 gtacaatcgt ggccacctca gagcgaaatt caggtaggct gcgctttagc tccttgacga
     1921 tagcctgtaa ataagaattc tgttgaattt gcaaaggtgc attttgctca aagtctacta
     1981 aaaggtcata aggattttca attttatagt tgagctgaag caattgatta accaactgct
     2041 tggacttgtg gaggcgcagc agaatatgga cgatttgctt actgttcata tcctctctag
     2101 tcagagtacg accattgagc cactcttgag cactcatcat atcgccattc cccatacgct
     2161 ttgcccaaag caattgtggg gcaatctgtt cctttgctaa ggcaggtagg attggtgttg
     2221 tattaagctt gataaagacg ctttcgccat ttggataggt ccctttgtag gctttgccac
     2281 tttttccgcg caagggagtc aatacaagat cctgttcggt tgttgtcacc ttatcccctc
     2341 cttttctatc ttctgtaacc agttatccct attttacttg ttttaaagga cttagtcaat
     2401 catcttcttt aacttgtacg gtaagtaaag aagatttaat aatcccatcg ccacaatcaa
     2461 cacaagagca ttttgccaag aacggcagag cacaagattg acgataagca tcaaaccact
     2521 taattgcctc aacaaagaaa gtagattcct ttgcttatgc tgtggtttag tcgggtaaag
     2581 cccactcata taatggtaat cataatgatg ataaagtgat aataactgaa aaagacttag
     2641 ataatgaaag accaaggcca agcctactgc taaataaggg ttggaaataa aggcaagtga
     2701 caagcaacta agcaacaaca gacgtaacca taaccctaga taatcagagc tgcgtaaaaa
     2761 tgctcttaaa tataggtttg tccaaacctt tttactatct gccttgataa gcttaagtat
     2821 aggattcaag taaggccttt ccttaacctt ggttgagatt cctttaacat ttgtaaacaa
     2881 agcataaaac tttaaaatgg cctgctggcg atctgcctca aaagcaatcg ctttttccca
     2941 atcaagcccc ttggagctca aaaagcttgc caccttacgc tttaacagta agcgcttagc
     3001 cagcaccaaa acaccaagca atagcacaaa ggcaagcaag gaaacaccaa gcctttgaaa
     3061 caaaggaaat aaaggtaaca gcaagaccgt ttgaaggcta gaccaaagaa taaaggacaa
     3121 gcgctctgct gacctgatat gggcaataac ctctgcctcc ttggtcagca aaaaatgctg
     3181 atcagccttt tcaagatagg tagcaactga ccccagatta agcaaaaaca agacagcaat
     3241 caacaaacct agctgaatcg gtagaggatt agcaggaaaa tgcttgagta gttgactgta
     3301 ctgaaaaaga ataaagccca aaagaaacag caagacaaga acaaaatgat cattaaagac
     3361 ataaggcaga tacttggtat gcttgtgctg aaactcctga cgacgcttac gaaataatgc
     3421 cttcatagct tacccctctt ttgtcagcgc taggtaaatg tcattaagac tagctgaagc
     3481 atctccaaag actgcctgca aatccgccag agtcccttgt gcacgcacct gtccctgatg
     3541 caatatcaca aaacggtcac acattttttc tgccgaatcc agcacatggg tactcattag
     3601 aattgacttg ccctttgcct tttcaacctc taaagcctta atcaaatcag caattgctaa
     3661 ggggtcaagc cccaaaaagg gctcatcaag aataaaaaga ctagggtcaa tgacaaaagc
     3721 gcaaataatc ataacctttt gcttcattcc cttagaaaaa tgcaccggaa accaatccag
     3781 cttatccgtc aaacgaaaca gctctaagaa gggctcagct cgcttatgtg ccagctccac
     3841 atcaatatca taggccatag ctaccgtatt gatatgctct gctaaggtca gctcctcata
     3901 caggcttggt gtttctggga taaagccaat tttcttgcga taatcagctt catgctccgc
     3961 caaggttaag ccatcaatgg aaatccttcc cttatatggc tttaaaaacc caataatttc
     4021 attaatcgtt gttgacttac cagcaccatt tagaccaata agccctacta gctctccatt
     4081 tccgacagaa aagctaatat ccttcaaaac tggaatatta aggtagcctc cagtgacatt
     4141 ctcaatgttt aacatatcat ttctttctaa tatctaatct attgtagctt tgcatactag
     4201 cttccctaga tgacaggtta ttagcctaga cagataggac ttactaggca atgctttgtc
     4261 atcatcagcc tatccagcgc tttgaagcac tgataagacc aattagcttg accctactta
     4321 agaaagctgg ggcagctaat actaagggta cacttatatt agctattata acaaatttct
     4381 gcacagagcg ttaactgttt tgatcaatgc tcccatcagc taaaaacgct gagtgaatct
     4441 gaagtctatt ttaagatcat caagaaaaag gcctagctat aaaaacagag gctatattag
     4501 cttgatctat cagtcctaac catctatcac atcatattcg aatgacctgg tgatcctaaa
     4561 tagcagctca tctaaggcgt catctaaaaa atcatgataa tattatctta ttgtattgaa
     4621 tttttaataa tataatgtta tcgttaacat gtaaataagt gttgcgtctt taatgacaaa
     4681 ggaggtatgt tatgaatttg tcacgctttt taacatttgg tttggtatca ctttcagcac
     4741 tttcaatttc aggcctagtc caaacagagg ctaaggctaa cgaatggcag actatctttg
     4801 aaaagccaca ggaggtggtt atcacagatg gctggcaaac tatctctgaa aagcctcagg
     4861 aagtaagcac ggctaacgaa tggcaggtca gctctgaaga agctcaagag tctgttcctg
     4921 ataaattctc acaaaacgaa gaccctagcc tatgggctgt tcctgataaa ttctcacaaa
     4981 acgaggaccc tagcctatgg gccgttcctg ataaattctc acaaaacgag gaccctagcc
     5041 tatgggccgt tcctgataaa ttctcgcaaa acgaggaccc tagcctgtag taaagccatc
     5101 cgcactcgat tgaagataag gcctatgttg ctgacgcttc aatctttttt tgttctaaaa
     5161 gctttctcag ccttaactgt caagaagttc cagcacctca tactctctga aactcttgtc
     5221 cttacaaata ttgtgccatg tcactaccgt acgatagtgc gcaaatgcac acctttgacg
     5281 gacctagctt gcagcaagta gcaggcttag ttatgtgctt aaccataatt gcttagtcca
     5341 ttatcatgat tcaaaaggct ttgctagtca tgtggtcgat aaccattagc accagctata
     5401 aacaattgca atatagacca gtacatgcta agataactat agtatgagat agctatggtc
     5461 actgagcaac tactgatttc ttattctaaa attattcaac tactgatttg agccattgct
     5521 acgcagacga aaggattatc acatggaaaa ttgtatcttt tgcagcatta ttagcggtga
     5581 gattccctcc tccaaggttt atgaggatga gcaggtactc gcttttttgg atatttcgca
     5641 aacaacagcg ggtcataccc tcttgattcc taaaaagcat gtccgaaata tcctagcaat
     5701 ggacgccgag acagctagcc agacctttga acgattacct aaaatcgctc gcgccattca
     5761 aaaagcaaca ggtgctactg caatgaacat tattaataat aatgaagagc tagctggtca
     5821 gactgttttt cacgcgcatg tgcacctcgt tcctcgctac agccaagaag acgggatcgc
     5881 tattcagtat acaacacatg agcctgactt cccagcccta gcagccttgg cacaacaaat
     5941 tagtcaggag attagccaat gactctaaaa acaatgacca caattggtct cacatccgtt
     6001 ttagcctacc aagtgtatcg taaacgtcat caaatcaaag aaactctagt agccatgcaa
     6061 acctctaaga aggctatcca ggccgatgtt gataggatta aggcaaatct cgccatcatt
     6121 caaaaggagg ctcgaacgct tcaagcagca ggaacagaat tagcctacaa atggcaggcc
     6181 tttaaccaag aagctcaggc ccatctgact gaaatccaac aacgtatgag caagtaccag
     6241 caggaaaccc cataagccta agcagactac caagcctcaa ggtgacaaaa aagggctcta
     6301 tcgtttctgt agtggacaag tccgctatag ggattatggg ctctttttgt atgtacaaaa
     6361 aagacgaaga aatcactcac aggatcaagc cttgatgaga tttcttcgtt tttttggctg
     6421 taccctaagg cgctgctggc gtaccagtgg ttgcaccact tgattgctgc tctgctggtg
     6481 agtctgcttg agggctagga gtcacattag ctgctcctga ctcttgtgta ccagctgttg
     6541 tgtcctgata gctgctgcta gaggacgtct ctgaggaata ggttgagtac tgggtagatg
     6601 agtctgtata ggccggtagg ctacctgaat tgtaataata gctgctatcc tgagtagact
     6661 gagtttttaa cgagccataa aggttttcgt aaactgtggc agtcgttttt agctgactaa
     6721 gcttttcaag gcctaattca gcacgaatgc gattttggat ttctaaaaga tgatctgagg
     6781 tcacaatttg ataggagccg ccatctgaca aggtcgctcc ctcacccttt agctgatagg
     6841 ttttgatatt tttaagggcg tctgtatagc ctaaaagatt aggaatggtt cgtgatgata
     6901 tttcaatgtt ggtttgcata ttaccactaa cagctgacaa gatctttcgg taggagctga
     6961 tactgttaag ggcaagaatc tttttcagca ccttttgaat aacctcgcgc tgacgcttct
     7021 gccgaccgta gtctccctct ggatcatcat agcgcattcg agcatagacc aaggcctgct
     7081 ctccatttat cttgtgagtt cctggtgcaa cggtagcctg atactcaggc tcattatctg
     7141 caatagagat aggaaagtca aattcattgg taacagtaat gccaccaaca gcattaacca
     7201 aatcaatgag cccttgcatg ttaatctgaa cgtatttgtc aatcgtgata ttcagcaagt
     7261 cctgaacggt catgatagcc atttgggcac caccagctgc ataagcagca ttcagcttag
     7321 cttctgctcc attcatctca ttatcatttg gacctgacaa agtgatgaga atgtctcttt
     7381 ctaagcttgt catggttgtc tttttggtct tagggttaat cgtaaccaga atcatagaat
     7441 cactatttcc ttgccaggta gaggttctgt gagacgatcc tgtgtcaact cccatcaata
     7501 gaattgaaaa gggctctgtc tgttgaatgg catcactttt tttggaggac gttgcaaaat
     7561 ccttaaaggt ctttgacaat tctccagttg aaaaggtata ggcattggtt aggtaaactc
     7621 ccatagcccc caaggtcaac agcacaatag ctgtcagcat taaaaagatt ttttttccaa
     7681 ttttcatcta ttcacgttcc agatatttac gcataaggta aacatcctga tagtctccat
     7741 ttcttgattt gacgtccttt cttttgacgc cctctatttt aaagccatat ttctcataaa
     7801 tatgataggc acaagtattt cgagcctgaa cctccagctc caaagcacaa agctgctttg
     7861 tttctctggc ccaatcaagg gtagtctcca tcaaaagctg tcctaggcca tgattgcggt
     7921 agggtttcaa gaccagcata aagcaatcgc caacatagct agtctcacga tatgctttgc
     7981 cagctatatt tagcagacca gctaatatat ctcccacctt tagcaaaagg caaatatctg
     8041 tcaaagactc ctgactagcc tctagaaaac actcaagcac ctctacggta gcagctatga
     8101 cgtcctcagt ccctgtgata aaatctgtct catcagcagc ttctttaatt agagtgatca
     8161 aagctgacgc atctgaggcc ttggcctctt cgattgtcac cacctgctca gacatgctta
     8221 agctcctcaa gaagtgcctc tgatcgatga ccatgtgcta gataatcaac ctgccggcct
     8281 gtttctgttt ttgttattaa aatttcaagg tagtcatgca gggttccctt ggctaaaagc
     8341 tcgccccact caatcacagt aaccccacca ccaaagataa aatcatctaa atcaatagag
     8401 tccggatcat caccaatccg ataaacatct aaatgataca agggtagtct tccctcatat
     8461 tctcgagcga tagtataggt tgggctttta atcatctgat caatccccaa acccttagca
     8521 acccccttgg tcagcgttgt tttaccagca cctaagtcac cagtcaagac aagcacatct
     8581 cctgccttta gctgtctacc aatgccttgc ccgtaagcga ttaattcatt ctcatttttg
     8641 ctataaaaca taaggctatt ataacagaaa aaaaacggtc ttccaagcct aagccagcct
     8701 gtcagcaaaa tattctaggc tcgtcagtcc tcatataatg tcgtcaaagc tcaatcagct
     8761 ttaacatctc ataaatcaaa agagccagca gcaaatcaca tggacctaac atcatggcat
     8821 tctgctgtga tagccagggc tgaatgctct agaaatcaac ccgcagctct aaaaccttaa
     8881 gacttagcct aaatatagga ctaggaaaag gtggcaatgc ctatgagctt agaaagtcca
     8941 tagtcccagt ccaaacggta atccctgtct ttattgtccc agcaaaaaag aggcacctaa
     9001 gtacctcatt agtcgtttac aataacgcta aaatgataaa attcaaaaca aataagaagg
     9061 ttgctcccca aagaatcggg tgaatctcct tggttttgcc cttcacaagc ttcaccaagc
     9121 aatagaaaat aaaggagcca gccacaccgt atgaaataga gtagcaaagt gccataaaga
     9181 aagcagcaaa gaaggacggt agggcaacgt caaagtcgct ccaatcaaca tcaaggaagg
     9241 acgataccat cataaccccg acaatgatta aggctggtgc agtcgcagcg gctggaacaa
     9301 ttcccacgat cggcagcagt aaaacagata agacaaagca gacagcagtt gatacagctg
     9361 ttagacctgt acgtcctccc tctgcaatac cagcagcaga ctcaacgtag gttgtggtat
     9421 ttgaggtgcc aaataaagct ccgattgaag taccaatagc gtcagcaaag agcgcacggt
     9481 ccatttttga gctaaagcca gagctgtttt ccaaagctct ctcatcctcc tcagagaaaa
     9541 tccctgttcg acgaccagtc ccaacaaaag ttccaatcgt atcaaaggta tcagatagac
     9601 taaaggcaaa gatcgtcatt aaaacaagcg gcaagcgact tgaatcacta aacagtgacg
     9661 ccatgccacc aaaggcagcc aagaatgttg tccctaattc agcaaaggct gagctgatgt
     9721 gattgtctgc aaaattaaca gcagaaagat caaccactcc aataggaata ccggctaaag
     9781 ttgtaactgt aataccaatt aggatggctc cacgaacgtt cttaagcaca agcactgctg
     9841 ttagcagcag accaaaaact gctagcaaaa cactcggatc ggtgaaggtt gaaatagctg
     9901 gaaccacacc accattagca ttaacagaga agacgccatt agcaaatgtt tcagcagttg
     9961 ccttagctgg ctcaacacca tttacagtaa caatctcagc agatgatagc gaaaaggtga
    10021 tcaggttagc atttttaaaa cctagataag caacaaagac tccaatacct ccgccaatag
    10081 catgctgcag gcttactgga atagccttga taatgctctt gcgaagcttt gtgacagtga
    10141 taaagatatt aaacagacca caaagaaaga caatagccaa ggcctcctgc caagaaaatc
    10201 ctaagctaaa aacaacagtg taagtaaaga aagcattaag tcccatacca ggagccaatg
    10261 cgtaaggcac attagcaaac aaacccatga tcaaggtaga gatagcagct gcgatgatgg
    10321 tcgctaaaaa caccgcttgc gacggcatac ccgctgcact caaaatactt gggttaacaa
    10381 ataagatata tgacatcgca aaaaaagtcg tcacaccagc catcagctct gttgaaaccg
    10441 tcgtgccatt ttcttttaac ttaaaaaact tttccatttg aatggagtct ccttattgat
    10501 aggcaaaatc aaaaaagccc ttatctcatc agataagctt tttctcttaa aaccaaatga
    10561 ttattatcgt ttttacgaac gatatattca tcgtaacatt ttatcgttct attttcaata
    10621 gcttttttcg tttatttgcc atgatcgttc aaaatttaac agcctttttt tctattaacc
    10681 gtccaagcag caattttctc ttccactgat cctaaaattt gttataatct agtgtatgac
    10741 taaaaaacta attgctattg atttagacgg gactttattg catcacgaca ataccatctc
    10801 tacctatact caaaaaacca ttaaggccgt ccaagctaag ggacatgagg tcatcatctc
    10861 gacaggacgt ccttatcgta tggctattga ctactacctt cagctagagc taaagacacc
    10921 tatgattagc tttaatggct ctttgaccca cctacctgag caaagatgga aatacgagca
    10981 taatgtgact cttgataagg cataccttct caaactccta gcagtgcagg aggacttcca
    11041 gatggacttt attgctagtg agtaccgaaa agccttctac attaccatga ataggcctga
    11101 gagcattgac cccaaccttt ttggtttgag gccatcacac cagatatggc tttacagatc
    11161 gacaaaatca cgcaggatcc aaatgctctt ctcatgcaaa cgcatcatga ggataagtat
    11221 gccctagcca aggccatgcg cgccttcttc aaggacgaaa ttgaggtgga ctcttggggt
    11281 ggtcccttaa atatccttga gatgtccccc aaaaacatta ataaggccta taccttaaaa
    11341 tacctgctta gcatttacaa caaggagcct aaggatttaa tcgcctttgg tgatgagcat
    11401 aacgacacag aaatgctggc ctttgccgga accggctatg ccatgaaaaa tgccagccct
    11461 gtgctgctgc cctttgccga ccagcagcta gcttactcta acgaagagga cggggtcgcc
    11521 agaaaactag aagagctttt cttgtgaaag caaacgaaac cattgttttt cagaaaacga
    11581 tggttttctt aatgccgttt ccgtcaattg atgaaagaat ttctaatatt ttcgttattt
    11641 ttcagcatat tttctttttt atgcggcata aaaatccctt tattatcaat attctactta
    11701 ttcggcagcg cattatgaaa attttttcat atttcgtaag atttttccga aagggcttga
    11761 tttttaagtg aaaacgtttt aaaatagaga cgttcttgaa tttcgttcaa gtgaaaaaga
    11821 attgccaaat gctatttgga aggagattat tcttcttcat ttcaacgaaa aatattttaa
    11881 taaggaggaa gaacaagaat gggtatcggt attattattg ccagccatgg taaatttgct
    11941 gaaggtattc atcaatctgg ttctatgatt tttggtgaac aagagaaagt tcaagttgtg
    12001 actttcatgc caaatgaagg accagatgac ttgtatggac acttcaacaa tgctatcgca
    12061 caatttgatg ctgatgatga aatccttgta ctagctgacc tttggagtgg ttctccattt
    12121 aatcaggcta gtcgtgtggc aggagaaaat cctgatcgca aaatggctat catcactggt
    12181 ctaaatttgc caatgcttat tcaagcctat actgagcgtt tgatggacgc caatgcaggt
    12241 gttgaacaag tagccgcaaa catcattaaa gaatctaagg acggtattaa agcccttcct
    12301 gaagagctca atccagttga ggaggcttct acagctaatg gtggtggtca agcgcttcaa
    12361 ggagctattc ctaagggaac tgtcattgga gatggtaagc taaaaatcaa ccttgctcgt
    12421 attgacactc gtcttcttca tggtcaggta gcaactgcat ggacaccagc ttctaaggct
    12481 gatcgtatta ttgtagcgtc agattctgtg gctaaggacg agcttcgtaa gcaattgatc
    12541 aagcaggcgg ctcctggtgg ggttaaggct aatgttgttc cgatcaataa attgattgag
    12601 gcttctaagg acccacgctt tggcaacact cacgctctta tcctgtttga aactgttcag
    12661 gacgcccttc gtgcgattga aggcggcgtt gagatcaaag agctgaacgt tggatcaata
    12721 gcgcattcaa caggtaaaac aatggttaac aacgtattgt ctatggacaa ggatgacgtt
    12781 gctgcctttg aaaaattacg tgatctaggt gtttcatttg acgttcgtaa ggtgccaaat
    12841 gattctaaga aaaacctatt tgagcttatc caaaaagcaa atgtgcaata agcaatttag
    12901 aaataagagg taggcttgtt taacgcaaca agctgtctgc ctcatctaca atgctgcgat
    12961 gatatgataa gcctgatgat tgcttctaga caaatcatca tcacttaata acgctttata
    13021 ttgtccattg acaattgact catatacgaa aggataacaa aatgtcagat atttcattaa
    13081 tttctgcaat cttggtcgtt atcgttgcct tctttgccgg tcttgaaggt atcttggacc
    13141 aatttcaaat gcaccaacca cttgttgcgt gtaccttaat cggacttgtg actggtcacc
    13201 ttgaagcagg tgttatgctt ggtggtactc ttcaaatgct tgcacttggt tgggcaaaca
    13261 ttggtgctgc tgtagctcct gacgctgctc ttgcatctgt tgcagcggct attatcatgg
    13321 ttaagggtgg cgactttact caaaaaggga ttacctttgc atactcaaca gctattcctc
    13381 ttgcggttgc aggtcttttc cttactatga ttgttcgtac catttcaact gtacttgttc
    13441 acgctgggga caaggctgct ttagagggta acttctctgc tatcgagcgc ttccactttg
    13501 ctgcacttct tcttcaaggc ttgcgtattg ctgtaccagc tgcacttctt gttgctgtgc
    13561 caactgaggc cgttcaaagt gtcttgaagg ctatgccagc ttggttgaat gaaggtatgc
    13621 aaatcggtgg tgctatggtt gttgccgtag gttacgctct tgttatcaac atgatggcta
    13681 cacgtgaggt atggccattc ttcgcacttg gttttgccct tgcagctgtg acccaattaa
    13741 cacttatcgc tatgggtgtt atcggtgtgg ctattgcctt tatctacctt aacctttcaa
    13801 aacaaggtgg taacggtgga ggtcgagcag gctctgctga cccaatcggc gatatcctag
    13861 aagactacta gaaaggggta agattaatga ctgaacaaat taaattaaca aaagctgacc
    13921 gtaaacgtgt ttggtggcgt tcacaattcc ttcaagggtc ttggaactat gagcgtatgc
    13981 aaaacatggg ttgggcttat gcacttatcc cagcacttaa aaagctttac acaactaaag
    14041 aagatcgtgc tgctgcactt gagcgtcata tggaattctt taacactcac ccatatgtgg
    14101 ctgctcctat catcggggta acgcttgccc ttgaagaaga acgtgccaac ggtactgcta
    14161 ttgacaacgc tgctatccaa ggggttaaga tcggtatgat gggacctctt gcaggtatcg
    14221 gtgatcctgt cttctggttt acagtgcgtc ctatccttgg tgctcttggt gcttctcttg
    14281 cacaaactgg taaccttgtc ggtccactcc ttttcttctt tggctggaac attatccgta
    14341 tggccttctt gtggtacact caagaatttg gctacaaggc tggatctgaa atcaccaaag
    14401 acatgtcagg tggtatccta caagacatca ctaagggagc ttctatcctt ggtatgttta
    14461 tccttgctgt ccttgtacaa cgctgggtat ctatcaactt taccatcaac cttccaggca
    14521 agcagctttc tgaaggtgcc tatgttgtct tccctgaggg agccgttaaa ggtgctgagc
    14581 taaaaagtat tcttggacaa gctatgggtg gcatgagcct tgataaagtt caatcacaaa
    14641 cccttcaagg gcaattagac tcattgatcc caggacttgc tggattacta cttaccttcc
    14701 tttgcatgtg gttattgaag aaaaaagtat caccaatcgc aatcatcatt gccttgtttg
    14761 catttggtat catcgcacac cttcttcaca tcatgtaata aaaattaagg aattgggggc
    14821 ttcccagttc cttaattttt ggctgtctag agccttagca aaggccagta ttcagcctgc
    14881 tacaagctat atttttatgt tataatagac aaaaacacta aaggacttat tatggcacaa
    14941 tctttaaatc aaagggtgat ccttcagaca acagccgtct cctatcttgg aatcggagga
    15001 aaggttggga aaatcttact tggagataag gctttggaat tttacaatga taaaaacgtt
    15061 gaggacttca ttcaaattcc ctggacggcc attaaccaaa tcggtgccaa tgtttctggc
    15121 aaaaaggtca gtcgtcactt tgaaatcttt accgatcaag gcaaatttct ctttgcttca
    15181 aaggattcag gaaaaatctt gaaggttgct agagaaacaa ttggcaatga caaggtcatc
    15241 aagctaccaa ccttggtcca gaccataata gcaaagctat ttcatcatca aaaaaaggat
    15301 aagaaatctc attgatgggc ctgccttaat tcaatattac ggtcatagac cagcatgata
    15361 atactcttag acatagcacc atagcaatat gtctaagagt ttttttcgtt gctaacaaaa
    15421 aagcttgaaa aacaagctta cagaatgtag acaaacccta tcagcgatag aaaaattgaa
    15481 aatttagaaa ttgactatca tataatgaaa actctggaaa atgctgatat tacagtattt
    15541 ttcagaattc ttttgttttt ttgattaaaa gaaaaagctt gaaaaacaag cttaagtgaa
    15601 tcctttctac aatctaaatc taaccttatt cctcatcaat ctgcaaaggg gattttcttg
    15661 tccacccatt tcaacaaatt ttgaaagcct agttttttaa aaagcatcag ccttgcctgt
    15721 tcaaccagaa aggacaaaaa ataaatcaca atgccgacgc caaatatcag tagtgggtat
    15781 aaaaggatag gagcattgac aaagggctct gcaaaatcgc gaataataaa tttgaccagc
    15841 aaggggtgta agtgcaccag ataaatacct agagtcgttg gagacacgat cacaataaag
    15901 cgtagcagca gtgtttctga tgtcagcttc agcttagcaa aaagaataaa taaggcaata
    15961 gctcccaagg tcaggctagg tgatacatac cagtaccaaa tatttcccac cataaatttc
    16021 atgatatagg taactaccaa agatcccata taaaccgcaa taagaagctt atgactaaac
    16081 ctacttagct ctatcctcct tagataggct ccgataatgt agagaataat cagccaagtc
    16141 atttcaaagc ccttgcttaa ggaaaattca tcgacctgct ggttcatcag agctgggatc
    16201 aacgaaaaaa tagcaaaaac cagcagtacc aatcggccta gctgcttatt ggataaggta
    16261 ttgaggccac cattgatcat aggcataaaa atcagtaacc caaagtaggc ggtgatatac
    16321 caataattgc cactcactat gggaaagagg gcctgacgcc aattctctaa gctaactgga
    16381 aagccaaata gagcaaacaa aagggtcatc agaaagctat aaaagaagac ttgtacccaa
    16441 atattaacga ttttggaata tttatagggc gacttaatgc ccacatagcc actaatcaac
    16501 gcatagcaat tgaccgcccc ataaacaaga acctgaatca tccaggtaac aataaaataa
    16561 gaatctgcct caccttcgac agttgaccgc aagccgccct ttcccaaaac atgtgtgatc
    16621 acaatcataa acatggaaat gattcgcaat aaatctaaac cgtaatggcg gttcttatct
    16681 aatgtcatta catttttacg cataatatta gtttaccaca atttttaata tttaacgatt
    16741 tgattttgtc tgacaacgag attttttgtg cctctgacct aagctctact tgtcatcagc
    16801 cttttgtatt actgacgctc cgtgacagac acatgaaaaa gttttagcaa gaaaagaaag
    16861 ctttctgtat ttcaaggata tgtcttgttt tttatagact ttactatagg aaaaacattg
    16921 aaagtgtcta ctctaattcc aaaataacta gttcgcgcgt ttgatgtagc tgacactcat
    16981 ttgggagttt actttttctc cttttttgtt ataataggtc tagcggataa gtagtctggc
    17041 tctgtctttc agagagtctg tggttgctga aaacagatag aggagtcata cgaaattcta
    17101 ccgtctacca attaaatatg aattaagtgc acagattgtg aagctggatg gaaccgcgct
    17161 taggcgctcc agtgtattca taggctgtgc ttttttatct cgtcagaaat aaaaaagcga
    17221 tcagctagct ttgctcatgc tattttataa ctgactatct tatcaccagc tcaaaggaga
    17281 tttatttatg ctagatctta agcgtattcg tactgatttt gatactgttg ctgctaagct
    17341 caaaacacgt ggtgtgtcag aagctatcct aacctctcta aaagccttag atgaacagcg
    17401 gcgcaccctg cttgttcaaa cagaagagct aaaagcccag cgtaatatcg cctctgctgc
    17461 tatcgctcaa gccaaacgcc aaaaggaaga cgccagccaa cagattgctg acatgcagca
    17521 gctagctgct aacatcaagg caattgatgc taagctagct gacattgacc aagaaattac
    17581 cggtatcatc actgttttgc caaatactcc ccatgattca gttcctattg gagctgatga
    17641 agaggacaat gtagagattc atcgctgggg aaagccacgt cagtttgatt ttgacatcaa
    17701 ggcgcattgg gatcttggag aagccttaga tatccttgat tgggagcgtg gcgcaaaggt
    17761 taccggtgct cgcttcttat tctataaaaa tcttggtgca aggctggagc gtgcccttta
    17821 taacttcatg cttgatgagc acctaaaaga gggctatcaa gaaatcattc ctccttatat
    17881 ggttaatcat gactctatgt ttggcactgg tcaatatcca aaattcaagg aggatacctt
    17941 tgagctagat gggacaaact ttgttcttat cccaactgct gaagtcccat taaccaatta
    18001 ctatcgtggt gacatcatag atggtaagga gctgccaatc tactttactg caatgagccc
    18061 atcatttcgc tctgaggctg gctctgctgg ccgcgacact cgtggcttga ttcgcttaca
    18121 ccaattccat aaggtcgaaa tggttaagtt tgctaagccc gaaacatctt atgaagagct
    18181 ggaaaaaatg accgccaatg ccgagcatat tctccaaaag ctaaagctcc cttatcgtgt
    18241 cttggctctt tgtactgggg atatgggctt ttcggccgct aaaacctatg atttagaggt
    18301 ttggatccct gctcaaaaca cctatcgcga aatctcaagc tgctcaaata ccgaagattt
    18361 ccaagcacgc cgcgcacaaa ttcgctaccg cgatgaggca gatggcaagg ttaagctact
    18421 gcacacccta aatggctctg ggcttgctgt cggacgtacc gtagctgcta tcctagaaaa
    18481 ttaccaaaat gaggacggct cagtgacgat tccagaagtg cttcgtcctt atatgggtgg
    18541 actagaggtg atcaagccac gttaaagcca aagactggcc ggataaggtg ccaacaagac
    18601 gattaatggg ctctatcatt tctgtagtag ataaggacac agtagaaatg atagggcttt
    18661 tttctatgta caaaaaaggc tctttatcaa ttgtaggggg acaaagagcc gattaatgag
    18721 attgatccta acaataaaga agacctctgt aactcctagc taactgctag ccttacagag
    18781 gtcttttttg atgtccttaa tattttctaa agcgctggta gcgctgatcc aataattcct
    18841 ctaagggctt ggcctgtagc tgagtgattt cgtcaattaa gtgtgatttt atcatctcaa
    18901 caatctcact cgaaaaataa ccccgctccg gaataatccg atcaatgacg cccatttgat
    18961 acagctcagc tgcggtaatt ttcatgagct cagcagcttc agtagcccta gagccatcct
    19021 tccagagaat agaggcaaag ccttctgggc taagaacagc gtacatggtg ttttccagca
    19081 tccaaacctg atcagcaaca gctaaagcta aagcaccgcc tgagccgcct tcgccaataa
    19141 taatagcaat gataggaacc ttgaggtcac tcatttccat caagtttcta gcaatagctt
    19201 caccttgacc gcgctcctca gcacctacgc ccggataagc tcctgctgta ttgataaagg
    19261 taatcactgg acgaccaaat ttttcagcct gcttcattaa gcgtaaggcc ttacgatagc
    19321 cctcagggtg cggctgccca aaatttctag ccagattatc ttgaagattt tttccttttt
    19381 gaataccaat cactgtgacc ggttgatcag ccaaataggc aatcccacca acaatagagc
    19441 catcatcagc aaactgacga tccccatgca actccataaa ctcatcaaaa atcaggctgg
    19501 cataatctag agctgtcatt cgaccctggt cacgcgcttc ctttaatatt cttgcgacgt
    19561 ctgtcatgat acacctccat gaaatgccac caaatgagca atccgatcac gcaggtcagt
    19621 ccgcttcaca atagcgtcaa caaagccatg ctcttttaag aactctgcct tttgaaaatc
    19681 atctggtaaa ttttctctaa ctgtcgtctc aatgacgcgt cgaccagcaa aaccaaccaa
    19741 ggactggggc tctgcaataa tcatatcacc ctccattgca aagctcgctg tcacaccacc
    19801 tgtggtcgga tcagttagga tagtcaggta aaaaagccca gcatttgaat gtttctttat
    19861 agctgcagaa accttagcca tctgcatcag actcataatg ccctcttgca tacgggctcc
    19921 accagacgct gtaaaaataa caactgggag ccgctcacta atagccagct caaataagcg
    19981 agtgattttc tcaccaacaa cggtccccat gcttgccatg ataaaatgcg aatccatgat
    20041 ggctagagca agcctttgtc ccttgaccag agctgttcca gtcaggacag cctcatgcaa
    20101 gccagtagcc tgcctggcct tttgcagctt ggcttggtag tctggaaatc ttaatggatc
    20161 cttggtttca atatctgtaa acaattcctg aaaagagcct tcatcaacgg ttaaagtcaa
    20221 gcgctcctga gcagaaatcc taaaattata ggagcaggtc ggacaaatct ttgccggccc
    20281 cagatccttt tgataaatca tgtgcttaca ggcaggacac ttggcaaata attcgtctgg
    20341 cacctctgga acattacgac tgacagagct tttgagagaa ttattgggag taatacggat
    20401 atatttgtct tttttactaa ataaggccat atctactcct aatctttatt gtagctgggt
    20461 aaaaaggttt ccatcaaaaa cgacgtatcg taatcacccg caatcacttg cttgtctgaa
    20521 atcaagtcca tctgaaaatc aatattggtc ataatacctt caatctctaa ctcaaacaga
    20581 gccctttgca tcttcatcaa agcatcaaat cggttatctc catgaacgat aatcttagca
    20641 atcatactat cataataagg cggtatcgta taaccactgt aaacagcaga atcaatccta
    20701 agcccaacac ctccgcttgg taggtaaaga tctgtaatct taccagggct tggtgcaaaa
    20761 ttaaagcttg gattttctgc gttaatacga cactcaatag catggccagt aatcacaata
    20821 tcctcttgac gaactgataa aggaagacct gctgcgatcc gcaattgctc cttgacaatg
    20881 tcaacgcctg taacaaactc tgttacgggg tgctctacct gaacacgcgt attcatctcc
    20941 ataaagtaaa aatcaccgct ggcttcatct aataagaact caattgtgcc agcattctca
    21001 taggacaccg ccttggcagc acgaacagca gcttcaccca tcctttgacg cagtgttgtg
    21061 ccaatcgcaa tcgaagggct ttcctccagt accttttgat tgttacgctg taaggagcaa
    21121 tctctctctc caaggtgtat cacatgcccc tgtgaatcac ctaaaatttg cacctcaata
    21181 tgccttgccg gataaataac cttctccaaa tacatggcac cattaccaaa ggctcctaaa
    21241 gcttcttgac tagcagcgtt aaaagcagcc tctaaatcag cctcggattc aacctttcgg
    21301 attcccttgc cgccaccgcc tgcagcagcc tttagcatta ctggatagcc aatctgcctt
    21361 gcaatctcaa gagcctcttg ggcattgtaa acctcgccgt ctgagcctgg aataacagga
    21421 acacctgcct taatcatctc agcgcgggcg ttgattttgt cgcccatttt atccatgaca
    21481 gctcctgagg ggccaataaa cttgatgttc atttcctcgc acatggtcac aaattttgaa
    21541 ttttcactta aaaaaccaaa ccctgggtgg atagcctgcg cccctgtcac cacagctgct
    21601 gataagacag aattcatatt gagataggat tcctttgatc ttgacggtcc aatacagatg
    21661 gcttggtctg ccaagatcgt atgtaaagcc tctctatcag cctcagaata aacagcaact
    21721 gtggaaatgc ctaattctcg tgctgcacga ataatccgca ctgctatttc accacgattg
    21781 gcaattaaga ttttgttaaa cataggttct tttttcctcc acagacgatt agtcttttac
    21841 tgcccaaaag caaaggtcaa ggtcccacta gctgctaatt tgccatcaac ctctgccttg
    21901 gcctcaacaa ctgctattgt cccacgacgc ttaataaacc tagctgtcat gactagctgg
    21961 tctcccggaa ccacctgctt tttaaatttt accttgtcca taccagcgta aaaaacaagc
    22021 ttgcctttat tttcctcttt tgatagctcc aagacgccag cagtttgtgc caaggcctcc
    22081 atgatcaaaa cacctggcat gactggatac tgaggaaaat gaccgttaaa gaagggctca
    22141 ttgatagtga catttttgat ggcaacaatt tcatcgtctg aagcctctaa aattctatca
    22201 acaagcagca ttgggtagcg atgtggcaat gcctcttgaa tctgttttat atccatcatt
    22261 taatgcgtac caatccttgt ccaaactcaa ccacgtcctc attggccact aaaatctctg
    22321 tcacgatacc gtcgcaagga gcaggaatct cgttcatgac cttcatcgcc tcaacaatta
    22381 acaatgtctg tcccttttta acgctatcac caacagtaac aaatggaggc ttgtcaggac
    22441 cggcagcaag ataggccaca ccaacaagag gactgtcaac tacttctcct tctggctctt
    22501 gcagacctga agaagcaggg attgattcct gtttagagac aatctcctgc gtcaggctaa
    22561 taggggctac ctcctggtgc aaagtaacag gctcaggagc tggagctgcc atcggacggt
    22621 gctcattttt actaaataac agctccccat cacttgattt gaatgaaaat tcgcgtaggc
    22681 ttgacgcatc aaactgtgcc atcaaatcct ttatctcttg aatattcatt ttaatcctcc
    22741 caacgcttaa aggctaatac agcgttatga cctccaaagc caaaggtatt tgacatggca
    22801 taacgaatat cggcttcttt tccttggcca aaaataacat ttgcttcaat atcatctgac
    22861 agctcctttg tcccagctgt cattggaaca taattgtgac gtattgcttc tatggttgca
    22921 atagcttcca cagcaccagc tgcccctagt aggtggcctg taaaggactt ggttgatgag
    22981 acaggaacct ctttaccaag cactgcaaca atagcctgac tttctccttt ttcattagca
    23041 ggagttgagg tgccatgagc attcacgtag tcaatagctg ctgcatcaat accggcctcc
    23101 tgcaatgcta gattaatggc cttacgagca ccaagtcctt ctgggtgtgg tgaggtcatg
    23161 tggtaagcgt cacaggtatt gccgtagcca acaatctcag ctaaaatagt cgcaccgcgc
    23221 ttttgagcat gctctaagct ttccaaaaca agcatacctg atccttcacc catgataaaa
    23281 ccgtttcgat ccttatcaaa tggaatagag ctgcggcttg ggtcctcagt tgttgacaag
    23341 gcagtcaagc tctggaagcc cgcaatggca aattttgtaa tggctgcctc tgatcctcca
    23401 accatcatca cgtcttgaag accaaactta attgtacgaa aggcatcgcc aatagcatcg
    23461 tttgaagagg cacaggctgt attgattgac ttacatacgc cttgggcatt cagcttcatg
    23521 gcaacattac cagccgccat atttggcaag gcctttggta gagtcatcgg cttaacgcgc
    23581 tttggtcctt tttcatgtaa ccgaatcacc tgctcttcaa tctcttgaat gcctccaata
    23641 ccagacgcta caataacacc aaagcggtca gaatcaatcg cttcaatatc taggccagca
    23701 tgttcaatcg cctctgtcgc agcatataag gcatacaagg aatacatgtc aaagcgattt
    23761 agatcctttt tgacaaaata cttatcaaat ggaaaatcct gaatctctgc tgcattctta
    23821 acagcgaagt cactcgtatc aaattttgtg ataggcttaa taccaatatg acctgccttt
    23881 aagcttgacc aaaactcctc tggagtatgc ccaattgggg aagtcacgcc ataacctgtt
    23941 acaactactc tgtttaatgt cattttaata cctctatttt attgcattgt catgccgccg
    24001 tcaatggcaa gcacctgacc agtaatataa tcctgactag ctaggaagct tgctgcctga
    24061 gcaacctctt gccccttgcc aatacgcttc attgggattt gatttaagat ttgctcttgc
    24121 atcttttcag aaaggacacc tgtcatatca gattcgatga agcccggtgc aatcgcattt
    24181 acccgaatgc cacgcgccgc aacctcacga gcaactgact tggtaaagcc aatcaagcct
    24241 gccttggacg ctgcataatt tgcttgaccg atatttcctg ttaggccgac aacactagac
    24301 acattgatga tagcaccctg acgagccttt gtcatcggct ttaagaccga ttgtgtcatg
    24361 ttaaatgctc ctgtcagatt gattttgaga acacgctcaa agtcctcctc tgacatctta
    24421 agcattaatt tatcattagt gatgccagca ttgttaatca aaatgtccac agagccaagc
    24481 tgctcaatag cctcatcaac cattcgctta gcatcagccc cctctgaaac atctcctgag
    24541 atcggcacaa ccttcacacc gtaatcctta aaggtctcca ccagctcatc agaaatcgct
    24601 gagcgaccat tgagaacgat gttggcgcct agtcctgcaa attgatgagc cattgctagt
    24661 ccaatgcctc ttgttgaccc tgtgataaaa acgttttttc ctttaatttc catagcttag
    24721 cattccctcc tattttccca aatacaattg taggcttggc atatcttcaa cactgctgca
    24781 tagcagcttt ttgtcgattt ttttaataaa gcctgttaaa accctgccag ggccaatctc
    24841 aacaaactgg gtgataccgt tagccttcat aacctcgata ctatcataaa aacgaacagg
    24901 ctccatgacc tgacgcgcca ataattctgc aatccgatcc ttttccatga ccttagcctc
    24961 tgtatttcca accagtggca gatcaaagtc ctgaaattga atcttgctga gctcctctgc
    25021 caacctttga ctagcaggcg ctaaaagtgc tgtatggaaa ggtcctgaga cattcagcgg
    25081 aattaaacgc ttcactccct ttgcttttaa gatttcaagt gccgcattga cagcctcagc
    25141 tgtcccacca ataacaatct gtcctggcgt attatagtta gcaggtgaca caacaccaac
    25201 cgaagaagcc tcttgacaag cctcctcaat aagcctagcc tctgtattca tcacagctac
    25261 catcttacca gagccagcag gcgctgcctc ctccataaag cgtccccttt ttgcaactag
    25321 ctctagggca gtctcaaaac tcagaacacc tgccgcaact agagcagaat attctccaag
    25381 agaaagcccc gccaccatat caggatgaac cccataagag gttaagatac gataaatgga
    25441 gactgaagcg gttaagattg ctggctgcgt gtaggctgtc tggttcaacc gatcctggtc
    25501 ggtatcaatg agcttgcgta aatcatagcc taaaagctga ctagcctgat caaaggtgtc
    25561 acgagcaatg gcatattggt catacaaatc tcttgtcatg cctagtgtct gagcaccctg
    25621 accagcaaat aaaaaggctg tttttgtcat acttctcctt atttatatcg tttcgttttt
    25681 gtcatcagct gcaagagctt gccagcgctt agcttcttga ctaatcactg ctgctgcacc
    25741 atagtagata tcctttagga tggcttcaca gctttcttct gctctaatta agcctgcaat
    25801 ctgccctgcc atgacagagc cattgatcac atcaccatca atcacagcgt tgcgcagagc
    25861 tcctgctccc atttcttcga tgtcactagc agccttacga tctgctaaaa attctttttc
    25921 agccttagca taagctgatg ttagcttatt tttgatagag cgtaccggat gaccaacaac
    25981 ttgagctgaa atgacagtat caatgtcctt agccttcaaa attttatcct taaagctttg
    26041 gtgagcatta gattcctttg ccacaacaaa tcgagttcca acctgaacag cctcagcacc
    26101 cagcataaag gctgctgctg cacctcgacc atctgcaatc ccacctgctg caataactgg
    26161 aatagaaaca gcatctacca cctgcctaac caaggtcatc gttgtcaatt taccgatatg
    26221 gccaccagcc tccattcctt cagcaataac agcatcaacg cctaattttt ccatgcgctt
    26281 agccagggca acgctaggaa caactggaat cacgataata cctgcctcat gaaggcgctc
    26341 catgtatttc cctggatttc cagcgccagt ggtcaccacc ttgacacctt cttcgatcac
    26401 caaatcgaca atgtcatctg caaagggaga tagcagcatg atattaaccc caaagggctt
    26461 atctgtgatc gctttgacac gatcaatatt tgccttgacc acctctttag gagcgtttcc
    26521 tccaccaatg atcccaagac caccagcatt ggagacagca cctgctagat caccatcagc
    26581 cacccaggcc atacctccct gaaaaatggg ataatcaata ttaagtaatt ctgtaatacg
    26641 tgttttcata ataaccttct atgcaaagaa atcaggagaa taatttgata atcaaactat
    26701 cataataaga agaaagagcg agttagagcc tgaaagaggg tctaatctca ccctgatggt
    26761 tcgattatta catatcaatt gaccaactaa agcagttcat taatcagcag gctggttaat
    26821 cagtattctc gcttgtttga gctttatttt gttttttctt caacgtaggc aacaaggtca
    26881 ccaactgtgt ttaagccttc ttctgtttcg atttgaatgt caaaggcatc ttcaatttct
    26941 gagatcactt ggaaaacatc aagtgagtca gcatctaaat catcaaaggt agtttctaag
    27001 gttacttcct ctgcgtcctt gccaagctcc tcaacgataa tttcctgtac tttttcaaat
    27061 actgccattt tatgtctcct taatataaat atttatttta taaatgtgct aggcacatga
    27121 tataactaga ttttaacaat tagactgccc catgtcaaac ctccaccgaa gcccgacagt
    27181 aaaatatgct ggctgccgtc taatttaagc tgtccatttt ggactgattc agatagcaaa
    27241 atcggtatac tagctgcact ggtattgcca tagtgcatca tattttccag aaatttctct
    27301 cttggcatac caattttctt agccatctta tctaaaatac gccgattggc ctgatgtaaa
    27361 agcagatagt ctaactcctc cttggccaag cctgattgct caataattgc tgtaatgctc
    27421 cttgaaacat ctctaatcgc aaagtcaaag atagcacgac catccatctg aagaaaggag
    27481 ttgacctcct gtccttgaga aaatggtgag cgcagactgc tctgacctga tgtcaggctt
    27541 tgaccttgcg caccatcagt atgtaaggcc tcagctagaa aatgctgctg ctcgctggcc
    27601 tctaataaaa ccccaccagc accatctcca aataaaacag ctgtgcttct atcctgccaa
    27661 tcaataatct tagacagggt ctctgctcca ataaccaagc ctctttgata agcccctgat
    27721 gcaatcaact tatccgccat tgctaaggca aagacaaagc cactgcaggc cgctgtcata
    27781 tcaaaagcaa atgcattagt agcaccgata gcagcctgaa cctttgctgc cgtcgatggc
    27841 atgctagcat ctgggctaat cgtagcaacg atgataaaat caagtgcagt cgcatcatat
    27901 cctgaccctg ctaacaattg ctctgctacc cgaatggcta aatcactggt catctccaca
    27961 gtggaaatgt gacgcttctc aatcccagtc cgtgacgaaa tccattcgtg gctggtgtcc
    28021 atgatttgcg acagatcgtc attactaata acctgcttag gcgtataatg agctacctga
    28081 ctaatttttg aaaagaccat taaaccaaat cctccaaaaa ctgatgtaag ttccccaagc
    28141 cacgtaacag ggcttgcatt tcgtcctcat tcatatcagc gatcacatga ccgaccatat
    28201 ttttatggaa tcttgcatgg agacgatcca gaagacgccc ctttttggtc agtgacaggt
    28261 aaacaacccg tctatccacg cttgatcttg ttctttcaat atagcccttt agctctagct
    28321 tgtttaagct agtggtaacc gttcctaagg taaccatgag ctctcttgcg atgtcacttg
    28381 gcgttacctg ctgatatttt ccaataatct caattgtgtg catctccttt agagaaacat
    28441 cattaaattg acttgttttt aagctcattt cctcaataac caaaattctg ttgaaaatat
    28501 caactaaata ttgattaatc ttattatatt ccaagtaaac acctccctag ctgtaaaata
    28561 ctttgactat caaagtatat cagacatcaa agtattttgc aagcacataa gagctatttc
    28621 ccccgaaaat ttggccgcct cctatctcca taagccctga cgccctcttt aaagtcctcc
    28681 ttaaaggcca attcctcttg aatagcaagc tctttttggg cataatcctc ccaacctgca
    28741 aaaaagcttt gccataccaa agatttcatg ccggcgtagg aatttgaaga gccacgcctc
    28801 aaacgcttta acagctgact acaggtctta tcaagcttat ctgactcagc agctcgatag
    28861 acaaatccgt actcaagccc tttttctgct gtgaccccct caccggtcat caccagatga
    28921 gtcgctctat ttagaccaac ggcacgtgtt aacaagaaaa gaccaccagc atctggcgct
    28981 aagccgacat taacaaaggc ctgaataaat tttgtctggg tgctagcaat acaaaaatcc
    29041 accgctaagg caatattaaa ggccgcacca gccaccgcac catcagcaca gaggataacc
    29101 ggctttggca attgcttgat agcaaaggaa atatcctgaa ccagctcagc aatcctaact
    29161 agagactgaa catcatctct ttcaacagca ttttgcatct caaccaagtc accaccgact
    29221 gaaaagacct tgccctttgc cttaatcact aaaaagcgca gagaggggtt atccttaacc
    29281 aacctaatag cctccagaat ctcctgacag gctggaatgt taaagccatt agacacctct
    29341 ggacgattta aggttaaaat ggccagatcc tcttcaagct caaaaatgat attttgaaac
    29401 gtcatatcac tcctcttttc tgacagctta tttgattacc aaataatttt atgaccaaat
    29461 aatttgacaa tcaaattaat tactagacta tagtacacta gaatcagtcg ttatgcaaga
    29521 aaaagattgt aaaaaataca ttaaaattga ctgcgcaatt taaagcatgc agccctaaaa
    29581 ccaagctcag acctagcctc tatacctcta ataaaagagc ctaagacaaa agtgtcctag
    29641 actctgaaac tttggcatgt gctatgctca accattctat acaattgtga tcaatcgctc
    29701 atagagtgtg taaacaagac ccgcttaaat atcctctaga gcgtctttga ccttgtcaaa
    29761 gaaacctttt ttctttggag caatcggctt ttcgccacta gcctccgcaa aagccttcaa
    29821 ggcctccttt tgagcctcat tgagcttggt aggcgttaca atgtttacag ttacatgctg
    29881 gtctccttgg cctccgcctc gaagcttagg agcccccttg cccttcaagc gaaatacctt
    29941 accagtttgt gttccagcgg gaatagacat ggcaacatca ccatggaccg ttgggatatc
    30001 tactgtatct cccaaagcag cctgaacaaa tgaaatattc aagctgtagt aaatagtaga
    30061 gccattgcgc tcaaactgtt tacttggaag cacgtttaaa ataacgaaca aatcaccata
    30121 aggtccacca ttaaagcctg cttccccctg accctgtagg cggatttgtt ggccggtttc
    30181 aacacctgct gggattttta ctgaaacctt atgaaccttc ttttcatgac cagttccatg
    30241 acaggtatgg caaggctctt tgatttcttg accgctgcca tgacagacat cacaggtcac
    30301 ctgacgacgc atcatgccaa gtggggtctg cgtatcaaca ttgataaccc ctgagccatg
    30361 acatttacgg caggttgtag gacttgttcc aggcttagct cctgagcctg cacaggtgct
    30421 acaggttgat tcacgatgat agctgacctc tttttcggta ccaaaaacag cttcctcaaa
    30481 agaaaggttt accctatatt gaaggtcatc gccctgacgt ggagcattgg gattacgcat
    30541 accaccaccg ccaaaaaagc ttgagaaaat atcctcaaag ccgccaaagc caccaccatc
    30601 gaagccgcca aaaccgcctg cgccaccacc aaagccaccg tttgctccgg ctgccccgta
    30661 ttgatcatag gctgcacgct tttgtgaatc gcttagggtt tcataggctt cctgtacgtc
    30721 cttatatttt tgctcagctc ccggctcttt attgatgtct gggtggtatt tcttagacat
    30781 cttacggtaa gctcgtttaa tatcatcggc cgaagcgtcc tttgagaccc caagacgatc
    30841 atagtattcc gtattattca tttattcttt ccttcattga caaaaacaga cggagcgagg
    30901 cgccccgcct atttgatttt tatttattta gccttgctat gctattttct agcaattagg
    30961 ggaggggact atcgcctcag tttctagctt tactgagcga ccttagctcc tcacagctta
    31021 tttttcagtg aactcaccat ctacaacatc atcgccactg tttgttgagc ctgtatctgc
    31081 tgcaccttct gcaccagcct gggcttgttg tgctgcggct gcttgctcgt acattttaac
    31141 agcaagggct tgtgcttttt cattaagcgc ttcaagctta gctttcatat catcaaggtc
    31201 gcctgactct tgagccttct taagctcatc aagagctgtt tgagcagcat cacgctctgt
    31261 gtcaaagcct ttgccttcag tttctttaat agtcttttca gttgcaaaga tagcctggtc
    31321 aacttcattt ttaaggtcaa cctcttcctt acgttttgca tcggcttcag cattggcttc
    31381 agcgtctttc atcatgcgtt caatttcttc ttcagaaaga ccatcgttag atttgatgac
    31441 aatatgttgt tctttttgag tacctaggtc ttttgcctta acagaaacaa taccgttttt
    31501 gtcgatgtca aaggttactt cgatttgtgg gataccacga ggggctgcag gaatgtctgt
    31561 caattggaag cgtccaagtg ttttgttatc tgctgccatt gggcgttcac cctgaagcac
    31621 gtggatatca acagctggct ggttgtctgc tgcagttgag aagacctgtg atttagaggt
    31681 tggaattgtt gtgttgcggt caataagctt tgtaaagacg ccacccattg tttcgatacc
    31741 aagtgacaat ggtgtcacgt caagaagaac aacgtcttta acatcaccag tgatcacacc
    31801 accttggata gcagcaccca tcgctacaac ttcatcaggg ttcactgatt tgtttggctc
    31861 tttgccagtt tcagccttaa cagcttcaac cacagctggg atacgagttg aaccaccaac
    31921 aaggataacc tcatcgattt ctgacaagct caagcctgca tcagacagcg cttggcgaac
    31981 aggaaccttc gtacgctcta ctaaatcacg agtcaggtca tcaaattttg cacgagacag
    32041 gctcatctct aagtgaagcg gaccagcagc gccagcagtg atgaatggca atgaaatttg
    32101 agtttgagtg acacctgaaa ggtctttttt agctttttca gcagcgtcct tcaagcgttg
    32161 aagagccatt ttatcttgtg ataggtcaat accgttttct ttcttgaatt ctgctactaa
    32221 gaaatcaatg attttttggt caaagtcgtc accaccgagc ttgttgtcac cagcagttgc
    32281 aagcacatca aagacaccat cacccaattc aaggatagac acgtcaaagg taccaccacc
    32341 aaggtcaaag actaagatct tttcttcttt atctgtcttg tcaagaccgt aagcaagagc
    32401 tgctgcagtt ggttcgttga cgatacgttc tacctcaagc ccagcaatct tacctgcgtc
    32461 cttagtagct tgacgttgtg catcgttgaa gtaggcagga actgtgataa cagcctttgt
    32521 taccttttca ccaaggtagt cctctgcata gcctttaagg tattgaagaa tcattgctga
    32581 gatttcttgt ggtgtgtatt ctttaccatt agcagcaacc ttttcagagg ttcccatctt
    32641 tgatttgatt gagataacag tgtcagggtt tgtcactgct tgacgcttgg cagcgtcacc
    32701 gacaatgatt tcaccgtttt taaatgacac tactgaaggg gttgtgcggt tgccttctgg
    32761 gttggcaatg attttgcttt ctgttccttc aagaactgct actgctgagt ttgttgttcc
    32821 taagtcaata ccgataattt tagacataat attttttcct cttttatata tttatgatac
    32881 tcctcttatg tggcacggac gctagcagct tcctatggaa tctcatagct gaaatttgag
    32941 cctaaagtct caaattttcc gagtcataaa acactagtgt tttatgactt ttgccacggc
    33001 gaagagtatc ggtaatgctc acttcgttcg cttttgctag cgcaaaaagc agcaatctta
    33061 tttcttattt tcatagttta ccgtcatttc ggacatgatt cattttattg attagctatc
    33121 atcacgggat aattgcgacg tgagatagca aaatcgatac cattttgcta tcgagctagt
    33181 aaggagtcta ggcaagccgc cacagcggtt gccgtctaat gacgagccat ttcaatggcc
    33241 atcattagtg actagttgta cacaaccacc atcgctggtc ttagtaagcg ctcatgaagc
    33301 ttatagcctt tttggaaaac ctgagcgata ctatctgctg ggtggtcatc atctgctggt
    33361 agggtttgga ctgccatgtg cagattgtgg tcaaaggctt ccacaggaac ctcttcaata
    33421 ccttcttctt taagggcttg aacaaggctt tcttgcacca tttctaggcc ttttttgaca
    33481 tcatctgtca gaccctcaac agccaaagca cgctccaagt tatctaagct tggaaggatt
    33541 tttttagcta aatcctgtga acgatagcgc tgcaagcttt ggcgttcttc attcgcacga
    33601 cgctgaatat tttgcatttc tgcgtgagct ctgaggtatt tattttcaaa atcttctgct
    33661 cgctggagag ccaactctag ctcagatggt tcctcggctg cttcatcagc aataagctca
    33721 gctgattgat cagcttcttc aactggctct actgcttcct cagcagcctc atcaagaatg
    33781 tcctcttgat ccttgagctc ttcttttggt tttttagaca aggtgtctac ccctttctta
    33841 cattttctta aatcatatta aggccttagt gaacctcata atggttgctg tttaagtaac
    33901 ggtaataatc tcttagcttc acagccagta gctgaccaat cacattaatc aagctaacac
    33961 tacgacgata atccatatca actggcccaa ttaagcttaa gaggccaaat cctctgtatg
    34021 gaattaaaaa cttgtaggtc agcaaggtca cgtttgctag ggctggctca ctgctgtcag
    34081 caacctgaac cgttgccatc tcttcctctg atagactctg tctgatagat agggctaagc
    34141 gctgctcctc atcaagaaac tgataggtcg caagaccagc atagtcaagg gcagcaacct
    34201 tgccagagac aaaaatcgtt tctcgaaaaa gcccgacaaa gatataatca aacaaatcca
    34261 aaacattgtc tgtcaccgta aaatacttct gaacaatctg agggatttcg gttcgcagct
    34321 tgtaatgaac agtcataaca tctttgccaa gtaagcgatc agcaacaatg cccttaagca
    34381 ccagcaaatc acgattcata aaattcttag gaatggcaaa ctgtacggtc aacggcttgg
    34441 actcatctaa gctcaaaact gccaaggcat catgactaga tagctgaaca atatcaaagc
    34501 ctgtcagcct ttgccttgca ggctcaacat ctaaaatcgc cgccgtatag ccggtcgtat
    34561 ccgatagcat ctggctggct cttagcaaaa cgtcctccag cttaaaggcc tcaaaatcaa
    34621 aggccttgac cagctgataa aggtcctgct catcaatgct gccaagatta agagaatgct
    34681 ctacaaaata tttaaagcct gccgcacttg gcatgcgccc acttgatgtg tgagccttct
    34741 ccagcaatcc tagtttttca agctttgcca tgtcatttct aatagtggca ctactagaag
    34801 caataagtga ctgcaaagcc ttagagccaa ctggttcatg ggtctgtgta aataaatcta
    34861 caataagatt caaaatatta gattgtctct ctgtgatcac aaaccaatca ctccctttct
    34921 gttagcactc tatacatcgg actgctaatt tataattcta ttatatcctt ttaaactagc
    34981 atgtcaagaa aaaaactcaa aaaattagca ctcttttttt agagtgctaa tttttataaa
    35041 acattgacag tgttgccttt gacattatgc ttgaaagaag taatagagag ccacttacta
    35101 cctctcagac tggtattggc ttctcccgac tcgctagcta aaaggagcgc taagctgtaa
    35161 gggggattag cttaactgcc tgaagcctta aggcctaaca atcaagcctt tagtagagca
    35221 ggataaatca ggctgcgtgc tcacagctcc tactcttaag gcttacacct tcaagctgat
    35281 agaaagttgc aatacctact aaagcaaata cctgagctta ccggttgttt cggtgtcttt
    35341 ttcatctcct caatcatcat agcttgtcaa acctcttgct tcaatcagct gcacaagcct
    35401 ttgggcatag cccttatcat cagaatagcg ataggtctgc agacttttag caggtttttt
    35461 ataccctttt tcggttgcta ggctttggta aagctttttc tcctcgcctg tgccttgact
    35521 aagccatgat aagtaagctc tgatagagtc ctctctgtcc cgatagatag cataggctgt
    35581 cttgtgcttt gaggctgctt gcttcttgag gctaatggaa gcctgccctg gagctggctg
    35641 cagtgaaaaa aggttgtggt atttggccgc caacagggtt ctgccataat tggtttctaa
    35701 aataatctga ccaatcaaaa tagaaggacg aatgccatag tttttggcca atggcttgac
    35761 ctccttagca accaactgga taaattgcct ctctgtatag ggaacagaca tctcctgact
    35821 ggccgatgtg cctttggcat tgaacagcaa gggaccaatc aaagccacca taatgaacac
    35881 taaaaacact agaaaatagg aaaatttaag tcgttttctc attttttctc cttcaatcgt
    35941 gttaggtatt cttctaggct gaggctatga gcggtaatgt atagggcaga ggctttacca
    36001 acatagcgat aatgccagtc ctcatactca atccctgtgc tagtctgctt cccttttgga
    36061 tagcgcaaaa taaaaccaaa ttgtggagct attttttgaa tctcctgtgc caccttagga
    36121 tcactagcgt ttaagttatc tactgtgctc atatcaatgg ctagaccagt ctgatgttca
    36181 ctagtgcctg ctggctgggc atatttccga accaaggctt cagctgcctc ttgggtcagg
    36241 ctaggatcat ttgccagctc ttgggcaata taagactgat aaagctcttc ttgctggaca
    36301 accgaacgat aaccagcaat caagtgctcc tgaggttcaa tcgtctgcgc cgctgctaga
    36361 aaatcagccg tctcctgctc aatgcgctta tcaataggaa tcccattaat ctcaaccaac
    36421 tcaggactca tttcctcttg agggtgatcg cgattgacaa ggaccagctg ccagtccgta
    36481 gttgatacct ttggcagatc agtagtcttt ttagcctgct tagctgcctt tggggcaggt
    36541 actgtttgat tagccttggg gcctacagcc tgtttttcag gcttgataaa gaggtaaacc
    36601 cctgataaaa acaacaggac gaccaaggcc tgtaaaagga ctcttatagt gttattcttc
    36661 atctcttatt gactcaatta tctcacgacc acgatagcgg tagctcatat ctccaatcgt
    36721 tttgatggta aactgcccat tctcatattc cacaacagtg acgcttccat tgtcaatgta
    36781 ttgcttttcc ctatctgggt caattagcca cataaaggtt ccaatggtca tgccatgact
    36841 aaccacgata gcattgccac ctcctgcatt ttcaacagca agcgcgatag cctcaaagcc
    36901 ctcatagata cgcttgctca atacctccca gggctctgcc cagttagcag tatcaacctc
    36961 gacaatactc tctgctaatt ctgaataagg cacatcacgc agattgtcac gattttcaaa
    37021 ggcctttgtt ctaggtaaaa cacctaaaaa cagctcggaa tcataagccc catctagact
    37081 accaaagcac cactcacgaa tccgcttatc tctagtgtag ggtaaaaact cattttcaga
    37141 ctttcgtaga ataatctcca ttgtctgcat ggtacgacct gaatcactcg aaaaagcagc
    37201 cttgaatgga ataccagcag ccttcaaacc aagtcccaat tcacgaatcc cttcttctcc
    37261 tgcctttgtc aagggggtat cactccaacc ctgtgcacga ccaatggtgt tgaacatcgt
    37321 cttgccatgt ctgacaatgt ataatcttgt ttttgtcata atgaacctcc aaagtctctc
    37381 tgctattata gcattaaaag aaaacacttg caaaaccatg caagtgctag ccgttaattc
    37441 ttaaagctat ggataggagc tggtatctgc ccaccacgag caataaagtc agccgatgaa
    37501 tgcggattaa cagccataac cggagctgtc cctaaaagac caccaaaagc aatcatatca
    37561 ccctccttac cctttggaat aatacgaaca gctgttgtct tttgattaat caccccgata
    37621 gctgcctcat cagcaatcat ggctgcaatg gtttcagacg gtgtctcctc tgggatcgca
    37681 atcatatcca aaccaaccga gcaaatggca gtcatggctt ctagcttttc aagattaagc
    37741 gagcctccct gcactgctgc aatcatgccc tcgtcctctg atacagggat aaaggcacct
    37801 gacaacccac ccactcggtt gcaagccatg acaccaccct ttttgactgc gtcattaagt
    37861 aaagctaggg cagctgtcgt gccatgtgtg ccaactattt caagtcccat ctcctctaag
    37921 acacgtgcca cagagtcacc aactgctgga gtgggagcta gcgacagatc cacaacacca
    37981 aagcccacac ctagccgctc acttgccatc tgtcccacta gctgaccgat acgcgtgatt
    38041 ttaaaggccg tttttttgac ggtctcggct agaacgtcaa agctttcacc acgaaccttt
    38101 tccaaggctc ttttgaccac accaggtcct gaaacaccaa cgttaatcac cgtatccgcc
    38161 tcaccgacac catgaaaggc tcctgccata aaaggattgt cctcaacagc attagcaaag
    38221 actactagct ttgctgcccc tatctcagag gctttggcgg tttccttgat gatacgcccc
    38281 atgtctgcaa ctgctgtcat attaatacca gaccttgttg atccaacatt gaccgaagcg
    38341 cagaccttct gtgtttgagc caaagcctga ggaatagact caatcaaaat cttatcaccc
    38401 ttttgatagc ctttttgcac aagagctgaa aagccaccga taaagtcaac tccgatatca
    38461 caggcagcct gatccagagc ttttgcaagc gacaggtagt cttctgcgtc tgttgccgcc
    38521 ccaataaggg ctatcggagt tacagagacg cgcttattaa caatgggaat acctagttct
    38581 gctgcaatgt catcaccaac cgccacaaga ttagctgcct ttgtcgtaat cttttggtaa
    38641 atcttagcgg cagctctatc aatatccgaa tcaatacaat ccagcaagga aattcccatc
    38701 gtaatggtac gaatatcaaa atgctgctcc tcaatcatct caactgtttc acgaacctgt
    38761 ctaatatcca tagtcatcaa gctccttata tgttatgcat agcatcaaaa atcgctgcgc
    38821 tttgaatatt aatcgtcacc tgcaattgct ttccataagc ctgaagcacc tcacgcagat
    38881 gagcaaaatc ctgcttttca ctgcttgaga caatggccat catggtaaaa taatcatcta
    38941 aaacggtctg tgaaatgtca tcaatattta accctaatgc agcaatttgt cctgaaacac
    39001 ctgcgacaat cccttgattg tccttaccaa caactgtaat gatagctttc atggcacacc
    39061 tcctcaatat gtgttatatt ttatcacaaa caaaaagaga aagctatcag agacaagagg
    39121 tctggtagcc ccttgcaaaa atagaacaat gggtaccaga aaaaagagtt tgttatccaa
    39181 ttgataccgt ttattaatat ttagacttta taatataata gcagctaata aaagataaga
    39241 cgtttgaagc tgccaaaaaa gctgggtcta aggaagccca gcttttttgt aggttaatta
    39301 agggatagca gaagattagt cgggattgta agaatagccg tatcctctct taccacctct
    39361 atcagctaga ccatctaaat agccatttcc ataattatca ttataccctt gactatagtc
    39421 attatattcc tttggactag actcatcaaa ccgcttagga taatctcctt tgtgcttttt
    39481 gccaccatat ccatcctcat agccaactcg gtaaccatca cgacgaccat gattgtaggg
    39541 gtgttcgtct ttaagttttg gtgattcatc attttctccg cttaagcctt taccgtctaa
    39601 atcttccttt ggcttattct ctccatctaa tccttttaaa ggatttttac gattatttcc
    39661 ttctaaattc ggagttgatg ggggaccggc ttcacctcgt tcaccttgct ctggttcctt
    39721 ctgattctca ccattcaagc ctggaagcga aggacggcct tgattattac cactcaaccc
    39781 tgaaagtggg ggaccagcct cacctcgttc accttgctcc ggttccttct gattttcacc
    39841 attcaagcct ttttctggca gcttgggact attgccctga ggctttggtt gaggctgcgg
    39901 gctagaatta tccttaccta gatctaagtg ctgtggcttt ccttgtggct gatggtgatg
    39961 acctgaacca gagctgttac ctcctctcag ccccagtggc tgggaaggcc cttgattagg
    40021 aatagcctga ggctctgagg cctgtccact actatttcct tggctgttca cactgagaga
    40081 ctgaggttga ttcccatgat gacctgagct ctttgctgtc ggctgggacg ggctagtagc
    40141 ctgatgctga tgattagtag gctgatctga aggcttaggc tgcaagttat cctttttcgg
    40201 tggccgactg accattgaat ctgatgagct cttgtgcgac ttatcgtcat ctccaatcga
    40261 gctgactggc tgctcctttg gcctcgcttg atgggatgag ccaccaagac ttcctaataa
    40321 acctccaaag acaagtgcag ctcccagcag caagctggtc accactgcac cggcaaatag
    40381 ccattgtttt ttggacttcc atgtgcgaaa acgtccttct gtttttctca tactttttta
    40441 actctctcca tattttttgg taaaaatacc aagaaatagt atatatagtc aagactttat
    40501 catatttctt ttaaattttt atcatctgat atattcgatt gtttttacaa atctgataac
    40561 caaaaaatcc tcgtatcata ctgatacaag gatttttata tatttgaacg tcacaagtac
    40621 tcctggctta ttgttttttg ccaaagagcg ctgaagcaac aattatcaca atagctgctc
    40681 ctagaattga agggaaaaca gccatgcctg ccagctgaat accccagtcg ccaaacagct
    40741 tttgaccaac tgcagagcct atcaaaccag cagcagtcat tgtgaaacag cccatcgaat
    40801 ggcttttttc tgttatccta cctgcaacca tgccgataat agctccaaca attaatgacc
    40861 aaaccatcgc aaatctcctt tatgttttgt cttattatac catacccttg ccttatatca
    40921 gtcagatgat ggtggtcgct tgatattaag agcaagctgc ttttttctct tagtaagcaa
    40981 taagtctctc agcgatatca caagcactgc tattaaaatc aaggccattc ctaacagatc
    41041 aatagggtga aaaatctctt tcatcaggat aatcgcaaag cagacagagg caaccggctc
    41101 aattgaagcc agcaaggtag ccttgatcgg tccaatgatt gaagccccct ttagaaaaaa
    41161 ggtgtaggca aaaattgtcc caataccgat aatgccaaac agggcccgta gattcccata
    41221 agtcattgcc aatgggtact gccatgctct tgtcaggatc ggaaaaatca ctcctcccat
    41281 cagcatggca agaccaacaa tcagcaagct cccccagtcg gcaatcagct tagcaggctt
    41341 gatgacacag taagcatagg tcaccgctgc aaaaagcccc cagaaaagtc caataggatt
    41401 gattgccaga tgggaaagat caccatgaca ggccatgata accgttccta ggatcgctag
    41461 gcaaatagca cagctctctc ccacagccgg caggcgtctt gatttgaacg ataggtagac
    41521 cagcaccaaa atgggggaaa ggtattgcag gactgtggct gtaccagcat tagagtaacg
    41581 aatagcaagc agataggcat attgattaag tgtgagacca aatagactgt aaatcaacag
    41641 ctctcttaaa agccttttgt ccttgagtaa gctgatgaca gcctctcttt gccgcacata
    41701 agccatagct gacagcacaa gccctgaaat aatgagcctt agtgaggtca aggcattgat
    41761 gccgacccca tgagcaatta aatattgccc tgacacccct gagagacccc aggcgattcc
    41821 ggctagtaaa atcatggtac tgccttttcc atttcttgac atattatctt cctcttttta
    41881 atccatgcca tgataaggcc actcataata ccttgatagc tctagcctag acttcaccaa
    41941 gcctgcttaa cagtcattaa caacagaccg ataagctacc tcttacagct tcggatagcg
    42001 aggtattatc acagaattgt cctaaagagc ctaccatcat aaagagcctg aaaactctgt
    42061 ttcagactca atgccagtca taacgactcc ttaatccagc aatttttgca attcttgggc
    42121 taacaattgc tgagctatct gtgggttggc ttgccccttt gtggccttca tcagaaaacc
    42181 agtaaaggcc ttgtcagcat tgcgcttgcc tgatttgaaa tctgccacag cagcctcatt
    42241 gtcagcaaac acctgatgaa tgattggaat caagacagct gggtctgaaa tttgaaccaa
    42301 gccggccttt tccacataag cacgcgctga gccgccatgc tttgccaaat gaacaaaaac
    42361 cttcttggcg atttttgatg aaatcgtgcc atcagtgatg atcgcaatca tttccacgag
    42421 attttctggg gtcaaggcaa tctgatcaat cgtcttgccc tcagcattta agaattgagc
    42481 catctcaccc tgaagccaat tagacacctg cttaggatca ccaccaagtg ccacagcctg
    42541 ctcaaagaaa tcagacaaag cctttgttgc tgtcagctga cctgcatcat aggctgacaa
    42601 gccaagagca ttaatgtagc tagctcgcct gtctgccgga aatcttggaa gctctgcacg
    42661 catatcctca atccatgcgt catcaatctc aaacaatggc aaatctggct ctgggaaata
    42721 gcggtagtct gctgctccct ccttgacacg catgagaatc gttcccttac ttgcctcgtc
    42781 ataacgacgt gtctcctgac gaataacacc gccagagcgt aggattttgg cttgacgctc
    42841 cacctcaaac tcaagcccct tacgcacatt gctaaatgag ttcaggtttt tcaattctgt
    42901 ttttgtacca aaggcctctt gtccgtatgg tcgcaaggag atattggcgt ccacacgcat
    42961 ggacccctct tccatcttga catcagaaat accagtatac tgaatgattt cctttagggc
    43021 agtcaggtaa gcataggcct cctctggaga gcgcatgtca gcctctgaga cgatctcaat
    43081 caagggcact ccctgacgat tgaggtcaac ataggaataa ccatctgtac catgcgtatt
    43141 tttgccggca tcctcttcta ggtgagcacg ctcaatacgg attttcttgg ttgagccgtc
    43201 ctcaagagta atatcaatcc agccattgta gccaatcggc tcatcaaact gtgaaatctg
    43261 ataggccttg ggattgtctg ggtagaaata attcttacgg tcaaagtgca tgtgctgatg
    43321 aatagacatg ttaagagcaa gtgctgcttt gattcccgca tcaatgactc ccttgttcat
    43381 cactggaagg acacctggga aagaccagtc aatcacatta gtgctggcat ttggatcctc
    43441 tccaaaatga gctgatgaag gtgagaaaat cttagaattg gtattcaact ccacatggac
    43501 ctcaagtcca ataatggttt caaaattcat tacctgtcac ctccaaaaat cataggctgc
    43561 tgcttgtggt agtcagtagt cgcttcaaag gctaccgcta cctgatagat gacctcttcg
    43621 ctatattttg gaccgatcaa ttgaagccca acaggcaagc catctgcaaa gcctgctgga
    43681 atagagattg caggcaagcc cgctagattc accggaatgg tcaaaagatc agccaaatac
    43741 atggcaacag gatcatgatt caacgtatca agctcaaagg ctgctgttgg tgctgttggt
    43801 cctaaaatca agtcataatc agcaaaaacc ttctcaaagt cttgaatgat cagcgtccga
    43861 acctgacctg cctttttgaa ataagcatcg taatagcctg atgataagct aaaggtacca
    43921 agcatgatac gacgcttaac ctcatcacca aagccctgac tacgcgtctt gacatagatg
    43981 tcctcaaggc tcttggcatc agcagcacga aagccatagc gaataccatc aaagcgctgt
    44041 aggtttgatg aggcctcaga tgaagcgatg atataataga cagccacccc atacttgcta
    44101 tgtggcagac tgacctcctc aatgatagct cctagcttct caaaatgctt agcagcagcc
    44161 aaaaccgtct ccttaatctt aggatcaatg ccttcgccaa ggtattcctt aggtagtgca
    44221 atcttcatgc ccttgatgtc ttgaccgatc ttaattgtgt agtcagcgat ctgtacaggt
    44281 gctgaggttg agtccttgcg gtcactccct gcaatgaccg atagcagctg ggcattttct
    44341 cttaccgttg gcgcaaaagg ccctatctga tctagcgagc tgccaaaggc aatcaagcca
    44401 tagcgagaaa cagccccata ggtcggctta agcccaacaa caccattaaa ggctgctggc
    44461 tgacgaatag agccgccagt gtctgagcca agagataagc gaacctgacc tgaagctact
    44521 gctgttgcag agccacctga tgaaccacca ggaaccctgc tatgatccca agcgtttttg
    44581 gttttcttga aataagacgt ttctgttgag ccacccatag caaactcgtc catattggtc
    44641 ttaccaataa caatcatatc cttgtcgtag gcattagcta ccgctgtcgc atcaaaaatc
    44701 ggctcataat tataaagcat cttagaagca gcagttgtca gaatcccctt ggttgagata
    44761 ttgtccttga cagctagtgg tattcctgac atcacattgt caggatcaat ccccttagca
    44821 tcaagtgcag cagcctgctt taaagcagcc tcgcaagcaa tggtaatgaa agaacccaca
    44881 gcctcctcac gcgccttgat atcctcaagg gttgcctttg ttagctcaac tgcagaaatg
    44941 tcctttgcaa caagaagctc atgtaattct tctatagtat gatgattaaa agacattagg
    45001 catctcctcc gtcatcaaga atagctggta ccttgatgaa atgattttct ttttcaggaa
    45061 cattttgaaa caggagcttg cgatccactc cagcctcagc gatatcagct cgcatgatat
    45121 ttttcttgtc tgccattgtg gtggtaatgg caacacctgt cgtatccact tcatttagca
    45181 attcaaccat gtcaacgatt tttgataatg ttgtcgcaaa ctcagttgtt tcactttctg
    45241 aaaaggatag ctttgatagg gccgcaacgt ggcgaacctc ttcttcagaa attttcatga
    45301 attctcctat ccaaggtaaa gcagaccatc atcagccaca aggccttgct gtttcaaacg
    45361 cttgataata gcctgaataa cccaatttta catagtctta accattatat cataattagc
    45421 tttatttacc atagcggact gctgggattt cacgtcaaat gcatgtggca actgacgttt
    45481 tctgataacg tttttcataa gctcaacctg cttttttcaa gaacagccag gctataacta
    45541 aactgcattt gagcaattga tgaggttaaa agggcaatgt ggctagagca tagctacctg
    45601 cattttattc acgtgtatgc gtagctggga ttagcgaaaa acttaataac aaaaagcctc
    45661 ctagccaaga ccaaaagatc tcactaagaa gcccttaaga tcagcgctga gccaagcagc
    45721 agctaatact gccttacttg attagcctat cccagctgat cgaacgatcg cctaagaaag
    45781 ccgatcaaga agctttgctc ctaggacagt cctacagtgg ttcagcgccc actggtgatt
    45841 ttctgttgaa ttgctcgcca ctgctgatgt gataatctca agcttgtagc ccaatttata
    45901 ggcatcaatc gctgtatgaa ggacacaaat atccgtcagc acacctgtca agaccagcgt
    45961 cgtgacgcca cgctcacgaa gacgaatatc caaatcagtc cccgaaaagg cagaataatg
    46021 ccgcttatcc agccaaaaga cccgctgatc ttgctggtat ctggtatata cggtcatcaa
    46081 aggaccatac aggtcccgac cccttgtccc gataatatta tgcggcggaa acaaggctgc
    46141 ctccggatga aagctatctc cctcctcgtg ggcatcaatc gcaaaaaaga tatagtagcc
    46201 ggcctcaaag gcagcctcaa caacgctagc catcgcctct gaaatcacct gagcaggtgc
    46261 tcctgccgtc aggctaccat catcagctac aaagtcattc gtgtaatcaa tagaaatcaa
    46321 ggccttcaca gcttatccct ccccaaaaag cttatgctct cttagctgca tgacagcaag
    46381 ccataagaac taagcctgct tttaatattc agtatgatta gacacttata gtttaccact
    46441 aaacacgaca gctgtcaaga cagcggattg atttatacac gataaaggcg aaaaacagtt
    46501 atttctgaac tatagtatag atttaagtag acactttcaa cgtttttcta tatgaaaata
    46561 agatatattc ctgaaatagc tgaacattga aatacagaaa gccttatttt cttgctaaaa
    46621 atctttcatg catctgtcat gttcatctca tgctgaatca cagcgaaaat acaaaaaata
    46681 cccctcaaaa gccagccaat gctagaacct ttgaggggac gctataataa tgtgtgaagt
    46741 cctccacagc tgctaagaaa ctccgataag ccgtcataaa gaccaagtct agcccttacc
    46801 aagcagggct ctggctaatg aatggctgct ctataagcag caagactttg atcatagcta
    46861 acactttcac tacctgctct gactaatcac agctagcaaa gctaaaggca agccttgggc
    46921 ttagcagacg atcgcatctg agctattaaa attcctttag cttgtcaaag atgccttcgt
    46981 taatcacctt gagataagtg cctttcattc ctagagagcg actctcaatg atacctgcac
    47041 tctctagctt tctaagggca ttcacgatga cagatcgtgt gattccaata cgatctgcaa
    47101 tcactgaagc ggtcaggcgt ccttcattgc catctagctc actaaggata gctgcaacag
    47161 ccttcatttc agagtaagat agagtgttga ttgccatatt aacaactgtc tgcttacgaa
    47221 tggtttcttc taggttttct gtttgaagat ttaacagctg aataccgacc acagtgcttg
    47281 agatttcaac taaaacaagg tcatcatcac tgaattcatt gtcgttacgc cagatgatca
    47341 aggtacctaa gcgcatgccg ccaccataga taggggcaat cgtggttaaa ccatcaggat
    47401 agatatcctt tgactcaata ggaaaaatcg ttagttcatt ttccacagaa aggtttgctt
    47461 cagtgtcata aacacgacta gctgccttga cataagcatc tgggaactgt cttgtttcaa
    47521 aaaattcctc gacgcggtct gtgttggtct tgtacttcat cgcatagcca agtaagctgc
    47581 cgccaccatt gatgatacaa gcattacaat caataatatc tgctaagcgt gaagccatag
    47641 tgttataggg gagttctgtt tccaagctgt ctacagaacg ttgcaaaata gaagtaatct
    47701 tacgggtttt ttctaataaa tttggcattt tttcttttcc ttttaattat ttgcgttaca
    47761 attatatcaa aggaccctag cttttgcaag gaattatcag aaaattggct attataccta
    47821 caattcggat gaggccagag ccttattttg ctgaaaaaca aaaaggatct cgcgatccaa
    47881 tttttgtatg agaatcatat tagcgcttgt attgcttgag aacatgcgtg atcttttctt
    47941 gcacgtcagc tagctcttct actgttggca gatagaccac gcgaaaatga tcaggctcct
    48001 tccagttgaa gccacgccca tgtaccagca tgaccttttc ttgcttcaaa agctgtagga
    48061 caaattcctc gtcgtcatca atgcggtaca tatttcgatc aattttcgga aacaaataga
    48121 ggcctgcctt aggctttaca gctgataggc ctggaatggc attaatggcc tggtaaatga
    48181 agttacgttg ctcaaagatg cgaccacccg gaagcaagag ctcatcaaca gactgacgtc
    48241 ctcctaagga ggtctgcacc acctgctgcg ctaagacatt ggagcacaag cgcatgtttg
    48301 ccagcatgtt caagccttca atgtaacctc tgacatgtct tttagggcct gacaagacca
    48361 tccagcccac tcgaaagccg gcaatacggt gtgattttga cagcccattc attgacacgc
    48421 aaaaaacatc aggtgcaagg ctggcaattg cgatatgctc cccaccgtcc atgaccaaac
    48481 gatcataaat ctcatctgca aaaatgataa gctgatgctc tctggcaatt gcaacaatct
    48541 cctctaagac ctctcgaggg tagagagcac ctgttgggtt attgggattg ataatgacga
    48601 tagcttttgt gcgctcagtg atcttggctt ttatgtcagc aatatcagga taccattcag
    48661 cctcttcatc acacaggtaa tgcaccgcat gcccaccacc taggctgaca caggctgtcc
    48721 aaaggggata gtcaggcatt ggcaccagca cctcatcacc attatcgagc aaggcttgaa
    48781 gagacatcga aatcagctct gagacaccat ttcccaaata aatatcatca atgtcaacat
    48841 caggaaagcc ctttagctga caatattgca tgatggcctt acgagctgaa aaaatcccct
    48901 tgctatcaga atagccctcg ctggagcgag cattgagaat caaatcacga ataacctcat
    48961 ctggagcctc aaagccaaag gctgctgggt tacctgtatt taatcgaagg atcttttcac
    49021 cattagctat catacgatta gcctcgtcca ggactggacc tcgaatatcg taggctacgt
    49081 gttctaattt tgatgatttt tcaattattt tcatagtctc attacctcgt aacccatatt
    49141 ataaaccaaa acaattaaaa tagaaagcac ttttctatga gcttaaagaa tgccaaaagc
    49201 tcaaccaaag ctctaagcaa gctaagcagc agctattaat aaggctatct aagctagctt
    49261 ctagctcaag gtatcctcac ctcagggaat agctgggcta tttggtgaac aatagctcag
    49321 aaaatcatta aaacgttttc aatttctcct caaaaaaggt ataatagcta tagagataaa
    49381 gttcaaagga ggataaaccg atgtcacaaa catatgaacg tatcatggtc gctattgatg
    49441 gctctcatgg ctccgaatta gcctttcaca agggggttaa tgtcgctttg cgtaatggtg
    49501 ctgccttgat tttgacccat gttgttgata cacgtgcgct gcaaagcgtt gcaacctttg
    49561 atagctacat ttatgacaag ttggagcagg aagctaaaga ggtcttgggg gattttgaaa
    49621 aacaagcacg cgaggcaggg ctgactgagg tcaagcaggt gattgaattt ggcaatccca
    49681 aaacgctatt agcgcacgat atccctgaca aagaagaggt tgatttgatt atggttgggg
    49741 caactgggct taacaccttt gagcggttgc tgattggatc atcatctgaa tatatccttc
    49801 gtcatgccaa ggttgaccta ttagtggttc gagagcatga caaaaccctg tagcaagacg
    49861 aattctctca gctgtcagaa gcatttgcag cctaagtgaa gtaaccatac ctagccctta
    49921 gcctcagctc acaaggctac taaaggacta ctgctctcat atactaatta ccactagcta
    49981 gacttaaggg cccttttatt gagggtgtct agtctacatc aaaaagcacc ctgagctaat
    50041 aagtgaagtg accccaagtg ttaggccaaa tgcttaacag ctaggagatc aactcacagc
    50101 tcaaggtgct ttttaatgcc tctaaaataa agacagcctt atttttccaa gcgctgcaat
    50161 gatttttgaa gctgcttgtc caactctttt ttgatggctg actctggtgc atagcgctcc
    50221 tgccagtcat ctggcttttg aattttatgc gttatgggat caaaatgcgc tttcccatca
    50281 gggaaaattt tccccatatt ggcttcatgg acggtctcaa aaatgggctg agggtccact
    50341 cccatcaata caaatgagcc ataggtaaaa taaagcagat ctgtcaaagc atcaacctgc
    50401 ccaaccaggg gtgactctgg gtgctccttg gcctgcacct tcttagctgc cttatcaagg
    50461 gcagcatgga ggtctatcaa agcctgagaa aagcgatgct tatccccttg actggctgca
    50521 taaagaaatt ccacaagttc ctctacctta aaatctgctc gatagccagc ctcctttaag
    50581 gaatagcctc ttggtgtttc aatcgtgtct ccgtccatca ggcggtggaa atccttgacc
    50641 ttgttgaaat tatcatcgcg acttttaaag cttttttcca catcaaaatg aatcaagcca
    50701 taatgcgcca gcgccttaga gataccatca ttgttatttg aagctgttgt aaagtgagca
    50761 ccgcttttaa ccactgcctc agcatttccc atcgcaacac caacaccaac gcctgagagc
    50821 atttctaagt cattatcaga gtcgccaaag gccatgacct ctgagagctc aaagccaaac
    50881 atctcgccca agcgttcaat gcccttgatt ttagactgcc cgctagaaat caaatctaag
    50941 gaataagggc tgcttctggt taccttgata tgcgggaatc tttccttgat tttttgggtg
    51001 tcatcaacag aagcaaccaa gacaatctga taaatcggct ctctcataat ggtaacaaga
    51061 ttgctgaagc tttgcggctt aaagcgtctg atgaggtttt taaagctgcc ctcaaccgtc
    51121 ttgaccagac tccttggcac aatactgcta accatctgac caaatggact ggttcccata
    51181 tcaatgatcc gagacccagc aagacctgaa gctgttccta aggagatctc gcgcttttta
    51241 tcgctagcat agcgaatgat tttataaatg gttgactttg gcagctggtt ctgatacaag
    51301 accttgtctc gtgtcaaaat gtattgacca ttgtaggtca ctgcaaaatc caagccaaaa
    51361 ttttctaaaa agggctgcac aaaagcaggt ccacgaccag ttgccagccc aaccataata
    51421 ccttgttttt ttaattgctg aatagccctt tgcgtcgttt tttgaacatt ttttcgatca
    51481 ttaagcaggg ttccatcaat gtcgaaaaag actgctttta ttgtcaaatc cttctgttct
    51541 ctcttctatt tgtgataaaa taaattatat cataaattga aagaagtatg agtatcaaat
    51601 gaaggaaatc ctcgtcttac ataccggcgg caccatttca atgcaggctg atgaagcagg
    51661 caaggtgagc ccaaatcaaa acaatccaat gaatcaggtt ggccttagcc tggagcatat
    51721 ccacctaact gttgtggatt ttttaaatct gccaagcccg cacatcaccc ctcaccacat
    51781 gctcaagatg tatcattaca ttcaacaaag ggctagtcag tttgatgcag tggtcatcac
    51841 acatggtaca gataccttag aagagactgc ttattttcta gacacaatgg tgctgcctgt
    51901 agagttgcct attgttatca caggtgctat gcgctcggcc aacgagattg gaagcgatgg
    51961 tatctataac tacctaacag cgcttagggt agccagccat gagaaagcca agggcaaggg
    52021 ggtgctggtt gtgatgaatg atgaaattca tgccgctaag tatgtcacca aaacgcatac
    52081 caccaatgtt tcgacctttc aaacaccgac tcatggccct ttgggagtcg tcatgaagga
    52141 cgatttactg ttctttaaga ctgctgagcc aagggttcgc tttgagcttc gtcatatttc
    52201 tggcacagtt ccgattatca aggcctatgc tggtatggga gatggaagta ttttaagcct
    52261 tttgacacct gataggattc agggactagt gattgaggcc ctcggcgctg gaaatgttcc
    52321 tcccctagca gtatctgagc tcgaaaaatt aatcgcctct gggattcctg ttgtcttggt
    52381 ctcgcgctgc ttcaatggca tagcagagcc agtttatgct tatcgcggag gtggtgccag
    52441 cttaaaaagg gctggtgtta tgtttgtcaa ggagctaaat gcccctaagg ccaggttaaa
    52501 attgctcatc gccctcaacg ctgggcttac aggtcaagag ctgaaggatt atatcgaagg
    52561 ctaagctctc ctataatcac aggctactac tcctcatcta tagcacaaaa agcacgactc
    52621 ggtcagctaa gaacctcttg tcgtgttttt atattagctc tgtccagcaa gtcagcctca
    52681 catctaatca aactgatcag cgacacgaag attagccaaa atcggagccc atctagggtc
    52741 cagctgccaa tccttagctg caacaatctc agcagcgact cgtcttgcct cctctaggat
    52801 atgataatcc tctacaatat cagctgtttt gaactctggc aaacctgatt gacgggtccc
    52861 aaaaatctct cctgagccac gcagcttgag gtcagcctct gccagcacaa agccatcatt
    52921 agtcgttgtc atgatggtca tacgctcctt gcctgagtct gtcttaggat ctgccaccaa
    52981 aatagcatag gattgcttgc tgcctcgccc aacacgacca cgcaactgat gcaattggct
    53041 aaggccaaag cggtcagcat tcatgatcag catgatggtg gcatttggca cattgacacc
    53101 aacctcaata acggttgttg acaccaagac atcaatctcc ttagccttaa agcgctgcat
    53161 gatcatctcc ttgtcgtctg ccttcatttt gccatgcatc aaggcaacac tagctgaagc
    53221 tttaaaataa tccttcagct cagcctctaa agctaccgca tttttcaaat ctagagtttc
    53281 agattcttcg atcaaaggag agataacata ggcctgtgtc cccttagcaa gctcggtctt
    53341 tacccaggcc agcacactat ctaattgccg atgcttgacc cagcgagtga tgattggctt
    53401 tcgccctgcc ggtaattcat caataatgga aacgtccatc tcaccatagg cagttatggc
    53461 tagggttcta ggtatgggag tagctgtcat catcaaaaca tctggattgt tgcctttttc
    53521 gcgaaacaag cgacgctgat tgaccccaaa acggtgctgt tcatcagtaa tcaccagccc
    53581 tagcttatga taggtcactg cgtcttggat caaggcatgc gtcccaacaa tcatatccac
    53641 agacccatca gcaatagccg ataaagctgc tcttttttca gctgctttca tacccgatgt
    53701 caacagggca atagacaaat ctggaaagag ctgacaaaga ctatcgtaat gctgctcagc
    53761 taaaatctca gttggcacca tgagtgccga ttgaaatccc gctgtttggg cagcatacat
    53821 ggcaaggctt gcgatcactg tcttgccaga gccgacatcc ccctgcaaca gacggttcat
    53881 atgagcccct gaggtcatat ctgctaagat ttcctccagg cttctttgtt gagctctggt
    53941 cagtgaaaag ggcaaagcag caatcttttt tgccactgcc tgctgatgaa aaggaatcgc
    54001 taacccattg ccctctgcct tgttagcaag ctttaaaacc tgcagattca tctgaaaata
    54061 gaaaaattct tcaaatttta tacggcgcag ggcctgctta taatcctcca tatgtttagg
    54121 aaaatgcatg gcataaacag cagcttgtct cggcagcagg cggtatttct gaatcaaggg
    54181 ctctggtaaa ttttcttcca gctgagctaa ggcaccgcta tcaaaggctg atctgatcgc
    54241 cttaatcagg gtgggttgac tgatcccctg cgccacatga taaactggct gcaaatcatc
    54301 ttctaaggtc atgagcaatt tcatacctgt caaggctgct tttttttgat cccacctacc
    54361 aaagatagcc acttcctgat ccaagacgat tttctcaagc agataaggct gattgaaaaa
    54421 gctgacacta atcacaagct ccccctgctt caatttaaag ctcaggcgat tacgcttgaa
    54481 cccatagtat tgaacgcttg gtggagtcac aactctacct gtaaggacag ccttttcacc
    54541 atctaaaagc tctaaggctg acttgctttt aaaatcctca tagcgaaaag gataatagag
    54601 tagcaagtcc ttgatctgat aaatgcctaa tttttgaaat ttctcagctg actttggacc
    54661 aagacccttc aaattagcaa tcgaactctt taacagcatc tcaacctcgc tttctttttc
    54721 attattatat caaaaatcaa gagcctctcc aaaaaggaag aggctcgttt tcttactgta
    54781 gatgccttga ggtattagcc gatcctaaca cacccttagt gcggccgcta ggacggccta
    54841 actaaaagat gaagagtggc atataaacaa tacagcactg cttgctaggc caagatatgc
    54901 cctagaattg tgatagctac tgctagcttg tcaagagttg gcggcttgtg attggtcaat
    54961 cgcagctagt ggttatcaga tcaagcagga acacctgctg ctccaaggag cgataaagcc
    55021 atcaccaata cagcaccaga ccgcttgagc aaggctaggc ctttacctgc tcaactgata
    55081 gatactatca caggcttgat ccagtaattc ctcgtcatga gagatgacaa tcactacctt
    55141 tttttgctgc tttagctcct ttaaaagact aaccagagcc tgcatttgca gcagatctaa
    55201 gccactgctt ggctcatcaa gaatgacaat ctccttgtca gacaagaggc tggcagcaat
    55261 catcaccctt tgctgctcac cacctgatag gctggcaggg tgcttgtcta gaagctgaga
    55321 aagcccaagc ctattcacca aatcatcagt agcctgatgt ctatgatgac ctagattaag
    55381 ctccttttct accgtctccg aaaatagctg tagcccaacg tcctgcaaca ctaggcttgt
    55441 gattgaaagc ctgtccttag caggcagggt gacacccaga tagctgatct tggcctcttt
    55501 tgcttcaaaa atacctgcca gatataaagc caactgcgat tttcccaaac cgttagctcc
    55561 ggtaatgcca gtgatttgcc ctgcaccaaa gctgagctga ttgaggtgat acaaaaccct
    55621 gctgcctgcc ttgacctcta gctgcttgat ttgcaaggca tgctctggat cataatgctc
    55681 aaaaacagtt tttgcccgca aagccttagt cacagcagtc aactcacatc gtcttagtcc
    55741 tagctcctca cgttcctgat ctggcaaagc tagcagatcc ttggggctta atacgcgctc
    55801 tagcctacca gctgaaaaat agtaaaaatg gtctgccaaa tccagcaaat aatgcaagcg
    55861 gtgctcagcg acaataatgg ttttgccagc agccttaagc tgctttaaat aagccttgac
    55921 cgctgctaca ctagcatggt ccaaattggc tgttggctca tcaaaaacca tgatagctgt
    55981 cccttgcatg atagctgctg caatagccac ccgctgcttt tgaccaccag atagcttaag
    56041 catatctgct tctagtaagt ccttgatgtc aaaatcagct gccaaggtat ccagcctctc
    56101 aaggataaga gctggctcta agccttgatt ttcacaagga aaaacaagct catgcttgac
    56161 ctcacgatag aaaaattggc tggctgggtt ttgaaagaca gaggaaacct gccttgacag
    56221 cacttcaaca ctagcctgac cagcctgatg agacagtact ttcagacttc cttgtaattg
    56281 tcctgaaaaa tagtctggaa tcaagccatt gagcagctta agaaaggttg acttgcctga
    56341 gcctgactga ccacaaagca cgataaattg acctgcctct atctgacaat ccctgagctc
    56401 acaggcagtc tgcctacgat tggtatagga aaactgcagc tgctttgcct tgatcactgg
    56461 agaaccatgt aggctatcgt cacaaatatc caaatctgta ccccccaatc cttccatgat
    56521 agatgtgata cgaagcactc acttgctccc tttttgattg ctagcccttt tgttaggcta
    56581 gcaatggtta agtcctgact acttctcagc aatgacatca acagcggtac caagagatac
    56641 tccatatacc gccttggctg tctgacaata gcccagctgt ccaagaaaat gcccctgatt
    56701 ttcagagatt gccgaataat ctttccttct tgcctgatct taggtaaaaa acgcagcatg
    56761 acagcaagag tcaacagaca aacctctggc acatgccatt ttcgcagccc atgcacaagc
    56821 tcgtaggcag tcgttgtctt gacaaaaatc aaagcagcaa gcacagatgg gtaaagcaat
    56881 tgaccagcaa cagctgcaaa gctcagcagc ctaaacagat aggctggcag cacatgaagc
    56941 ggcaatacag acaaagcaag cagtaaggca tagagcagtg tcataccgat tgccagacgc
    57001 ccttgaccaa gccaaaacaa aatgccaagc aaaacaccta taatcatcgt ccccagccag
    57061 ccatcaatcc gaaaaaagaa gcaggcattg gctagaatta acaggagcaa ttttgtgcga
    57121 acatcaagcc tcataaaagc attcctgact tagcaaaatg ctttttcagc aggtattgac
    57181 caaaaaggcc acctactaag gcacaaagaa ggacaacacc aacaaaccag ctaacatttg
    57241 caacggtaaa gtcatacatg atacggttaa catatgccat gtccttacca cgcgctaaaa
    57301 gactctggat ataggcgtcc ttcaacagcc acattaaaat aataggacca ctgttaacaa
    57361 aggcaaaaac aagataagac aagagattca ctagtctaga ttgatatttt cctaaaaggg
    57421 ctatgccatc tgccaaacag ccaaaaagaa tagctggtag cattgaagca aaaaaatgac
    57481 ctgtcaaaaa gaaaaagctt cccataataa ttcctactag gcttatcggt ccaaaggtct
    57541 gcagcttagc gattaatagc atataaactg gcccgccaag caaggccgca aaggctggcg
    57601 catagagcat attgcctgag cgatcaaaca gaatgctcag catggctcct agccccacac
    57661 aaacgaaata gagggcggca aaggcgcctg ttgtcatgat atctttaatg gttaaccctt
    57721 tcattgttta cctccttcaa aaaaccattt ctcacacaaa atagctggtc tgcacaggcc
    57781 aaggtggatg gccgatgtga aatcaaaaag accattcccc ggcaatgctt tttaatcaaa
    57841 tcaataaaga tggcttcatt cagcgaatct aagtttgatg ttggctcatc aaaaatatag
    57901 caatccgccc gcttcaatag agcccgcatc aattccaagc gctgggcttc accagctgaa
    57961 aagtctgctg atcctctcac tagggtatct agcccctcat cacaggctag gatacgctcc
    58021 ttcatgccac aggcctcagc aagttccatg atatcatcat ctgaaatgtc cttacgacca
    58081 agtgtgatat tgtcacgaag tgtttgctga aatagctgcg cattctgtgg gacataggca
    58141 aagttagcct gtagggaagc agcatttagc gtttgactgt caacctcact caggaaaata
    58201 tgaccagctt gccaattgta ccatttcata atgatcttca tcagagttga cttcccagag
    58261 cctgactctc cctgaatacc gataatgcct ttcttttcaa aagcgacgga taagtggtgg
    58321 taaatagtct cctgatgctt gggataagca aaggtcagat cctcaacagc aatccttgtt
    58381 accgaggaaa tacgctgatc tcccttatct actaacgctt cttcatctaa aagctgaaag
    58441 acattcctag cagcattcat ggcacgcttg aagccaagcg gcaaacgccc caattctaaa
    58501 aagggtgcaa aggaggctgt aaaggcaaca aaagccagca acccaccagc aaacgtcacc
    58561 gtctgctgac tcagctcaaa aagagtaaca taagcaaagg tcaaaataga caagccaaga
    58621 gccaaaaagg ttatcgccat ttgtaaaaat tgagcctgtg ccacctgacg atcaagcgca
    58681 ttaacatgct tgctctgatt ggataagagc ttaaagcgct tctcaatgct ttgaaattgc
    58741 agcaaatcct taacagatct gagactctct aaaaagcttg acacataagc cctgcgccct
    58801 tcattttgct ttttgagcag tgattgaagg acgtttgaaa aatacactgg aataataaca
    58861 gccaaaagca cataggtcac aatagccccc aaggctaact tccagctaac ctgccaaagg
    58921 taataggcca tcaagctagc tgaaataaac gccgtacaaa taggggcaag cgtgtgggca
    58981 aaaaagacct ccaaggcctc aatatcctcg ccaatcatct ttaacaggtg cccgctgtcc
    59041 tgactgtcta agcgtgccgg cgagagtgct cttagctttt taaagacaat cctgcgaaag
    59101 gctgccaggc tatgaaaggc aacaaaatgc ccaaaataat gctctccata acgaacaagc
    59161 ccccttagca gtgccatagc aacaaataga taaagccatt taaaggtaat agcatgacca
    59221 gccatcacct ctaagcccag ataggctaag ctggtaggaa tgccaacggt aagcacaaag
    59281 cccagcactg caaacatcac cgccagagct atccaagcca gcaaatgctt catcatagca
    59341 agcaatcgta aaactagccg gtaggtgctg taatcactct taaccataaa gatttgcctc
    59401 caattctact tgtgtatcaa ctaattgacg ataggccaaa tgatggcggt aaagctctct
    59461 tgggctagcc aagctagcag actgctcagg gcttaaaaag agcacctgat cagcctgctt
    59521 caaatatttc atcttatgag tgatgacaat tacaatggcc tgtttagcca attgctgaag
    59581 cagtctgtga atagcagctt cattctcagc atcaagactt gaggtagcct catcaaaaat
    59641 ataacaggaa cgctggctca ataaggccct agcacaaatc acctgctgtc tttgccctgc
    59701 agataagtga cagccattct cacctacaat ggtatcaatc ccatcaggta gccagtaaat
    59761 aaagctcaaa atgccatgct catcaatcca gctaagcagc tcctttctag tcagctgagc
    59821 tgccatagca aggttctcat aaatactcat attaagcagc gttgactggt cagaaacgta
    59881 gagtatttcc tgattgatgg cctgtttaga agccagatca atcgtcacat caccaaggaa
    59941 tatctgaccg ctatctgcct gatagcgctt caacaggagc tgtgcaagac tagtcttacc
    60001 ctgtcctgaa acacctgcaa cagctgttag ctcacccttt ttgatagtca tcgtgatgtc
    60061 tcttagcaaa gccttttccc catgtgaaaa ggacaaatct tgaatatcaa tacgatcaaa
    60121 ggccggtaag gcaactccct tgtcttggtc aacagcctca acactatcta aaaagccaaa
    60181 gatttgatct gccattttag tattcatcat gactaggtgc atgccatagc cctgctccct
    60241 aataggggca aaaaattccg ttgcaatcag gataaaaaag agaaagtcaa aaaaggatat
    60301 accaccagct gacagagcct gaaccgctaa aaagccagat aagccaatgc caagatacat
    60361 gacagcgtcc atatagccaa ccgcttgcag ctgaaagccc aagagctgca tggtagcctt
    60421 acgaaaggcc tctgccttat tgacaaagct ttcctcatac ctttcatctg cctgatagga
    60481 ataaagggta tttagcccct tgagatcgtc cataaataga ttgccaacgt ccatataggt
    60541 tgaccagtaa tggttcatga tccttttaga gcgtttttgc atagcaacaa tggatatggg
    60601 aatcaagggc aaagacaaga taaagaccaa gccccctata ggatagatca aaaaaacaag
    60661 cagtaagacc gttgtgcaat taaaagctgt tagcattgca agcgataggt aataggaata
    60721 ataggtatcc aagctatcaa tcccttgtga ggcaaccgtt aacacatcag cctctgttga
    60781 ctgctgatca aattgcccgt ccatagcaat aaaggcatca aaaaaggatt gcttgagcga
    60841 gtcacgcgca aattgcgaag ctaggccctg cagctgcttt gcaatcatcg ccaagccaaa
    60901 gccaacagca tttaaaatca aaaggataac aagcagcctt gtcaattgca gggcttgacc
    60961 tgctaaaaag gctgtgaatt gcttagcaat taagtaaaag ctcattaaac gcatcaaaaa
    61021 ttgcagccaa gataaaaagg ccgacacata aagcaaaaaa cgcttaggag caatacgctc
    61081 ctttaaacgc cttaaaagca tttttttctt tgcgcgtgat attttttcag ttgtatcgtt
    61141 catataatcg tcgccttatt cctatctatc attcattttt tatttgtctc ataaagtggt
    61201 aagaacaaat cgcctatcct gcttttcaat aaagggcaag ctcaccccaa aaaccgcctc
    61261 cacaaaagcc tgatcaagaa cctcctgtgg actgccttgg gcatagatgg cacctttttg
    61321 cagcccaagc acacaatccg aaacagccaa ggcctgatta atatcatgta acaccatgat
    61381 aatggtcatt cctagctcct gattgatttt tttgatgagg gctaaaatgt ccagctggta
    61441 cttaatatca agataagtgg ttggctcatc aagcactaag acacctgttt tttgggcaag
    61501 cgccatagca atccagaccc tttgcttttc accaccagat agctcctgca tttccctaaa
    61561 ggccaattcc cttagattag tcacctctaa ggcccaagca acaatgtcat cgtcctcttg
    61621 acttgatccc ttaaaaaaac gccgatgggc ttggcttgcc acagccacca aatcacccac
    61681 cagaagatct gctaccgcct gattatcctg atgcacaacg gctacttttt gggcaaactg
    61741 cttaagacta atagagctaa tagcttgtcc ctctaagaaa atttgcccag acttaacggg
    61801 gatattttta gtcagcagac ctagtagggt tgatttgcca cagccgtttg cccccatgat
    61861 tgtcgttatc ttgccttttg gaatggtaaa gctcagccta tctaaaatag gcctatcacg
    61921 ataagtaaag gacaaatcct ctacacgaat caagccttgc tcatgactca tatcacgtca
    61981 gacctcctta acagataaat aaaataaggt cccccgacaa tgctcatgat aacagctggg
    62041 ctaatctcca agggataaca caactgcctt cctaaggtat ctgccagcaa aaagacaaag
    62101 gcgccaagca gggcagaaaa aggaatgaga tagctatgct tactgccaac taaaaggcgg
    62161 ccaatatgcg gcacaatcag gcctaaaaat gacaccacac ccacaatcga ggtggaaaca
    62221 gcagctagta agaccgcaac caacgagatt cctaagcgca ggtaattact atcaatgcct
    62281 aaattacgaa tcaagccatc gtttagcagc agtagatcac actgccttgc taggcctatc
    62341 gcaagcagca ggccaagcac tgtataaggc cacagcacac caacatctgc ccaggttttt
    62401 tgactaatat ttcctgacaa cagcgcattg acaaagggat tgctggtttt tgaaaaatca
    62461 gtaatcgcac gagacaagcc taaaaacaag gcgttgatag ctattcctgt caaaatgatg
    62521 cgtatcggct gcaagccctt cttccaggac aaggtataaa tcatcaaaaa agaaacacag
    62581 cctcccacaa atgataacaa aggaccataa aacaagagct gcggcaaaag caggctagat
    62641 aacaagacca taaagctagc cccactgcaa accccaataa tcgccggatc tgaaatagga
    62701 ttttttaaaa tcgcctgaaa caagacccca gatgttgcta tccccgcccc agccaataaa
    62761 gcaatcacaa tccttggaaa gcgtaaatcg taaataaggg ctacctctga atcatatgct
    62821 acaaataagc cattaaagat cctctgataa gaaacagata agcccccaac agagaccgca
    62881 tatagcatta aaccaaacag cagcatgagc aatagaacca tatagaccag tctagtggtc
    62941 ctttttcttg ctgctgtgac ttgatcagaa tattgactac cttgctgcat cttacttgac
    63001 ttcctttgct ccataaaaga tttgtgacag atggttcaaa gcctctttgt agttaaactt
    63061 agcactcatg ccaaaaaggg tattgtctaa atcataaacc tgctgagact tgacagcttc
    63121 aaaatgcttc caaatatcat tttcagcaaa ttccttatca aacatgtcct taaccttgtc
    63181 tggaatggcg tgggcagtac gcaaaatcag ctcaggctgc tgctgaagca tgtcttctgg
    63241 attggcagac aaaaattcct tgtcctcaga gtgataaaca ttctcaccac cagccagctc
    63301 aagcagatta ccaacatagg atttatttgt agcaatcaga tagctgccag gaagccccat
    63361 caaaataaga accctaggct ttttttgccc tttatgcttt ttcttaaagg cccggtaaaa
    63421 ctcctcataa tcagcccgca agcgcttagc ttcctttttg cgatcaaaca agtcccccaa
    63481 atcatcaatc gactggtaca tgccttcaag gctagttaaa ttcaaaaagc catattccgt
    63541 atccaattgc tggtatttag gctctaaatc attttgcaga gaattgggac tgagtatcca
    63601 cgttggcttt agagaagcaa taacctccat atcaggattc atcggcagac cgatcctttt
    63661 gacagcatcg taacgctttg gcaattggta tagcttactg tcacagaccc caaccaaatc
    63721 taggcttagc cgatcacaaa tatcaacaac agccacagag gtggcaacaa ttctctcctt
    63781 atcagccttt ttctctgccc tagggtgctg atccacacaa gcagatagca ccaaggacaa
    63841 aacagctaat ccaataagct taatgacttt cttcattgtt ttttctcttt ttctttataa
    63901 acaagaccaa ggctcctgac aacaaaagag ctgttggtac atagtaaacc agaactggca
    63961 atggattatt tactggcttt tgggacgact cttgcttact tttatctagc gaagtgctca
    64021 aaccaactgc ctgacccttc ttagagggat ttgactgttt tttgggactg cttgattgac
    64081 caactggcct tgctgaggga ttaggagctg acttggcgtc ttttgagtcc ggtttactag
    64141 gagctttctt ctcatctgcc tttgcaggag ctgtcaccgc atgatccgtc ttggcttctc
    64201 ctgctgcaaa gctagctacc atatctccac tgtagccttc ttgtagctca gatggtgaca
    64261 ggtaaaagac aacctctctg cccataggct ctacgtacat gctgcctcta acaaccgtat
    64321 tgacatcagg caaagcaatc gcaatatcct ttgttgtgcc attggtatca gtgccaacct
    64381 tggtgacact gtaggctgcc gcctgaaaag cccctgtacc acccggctga acccaaaatt
    64441 ggtagttacc tgaaaaatca gctagactca tgcgaaaggt cagatacaaa tccccagccg
    64501 aggttacctc tagcatacca ttgctataaa ctgttccttc caccatacct tggccaatct
    64561 caaaagcgtg ctcaccaccg ctatcttcaa tttgccctga aaccgggtga cgataatctc
    64621 gcctaatcac acaggaataa agctcaccct tatcagcata ggccttacct cctatagctg
    64681 ctaggcaaac cagcaatacc accaagccac ccattaattt tttgaataat ctctttatca
    64741 tatgttcctc attaatgatc ttcatttcct tacgacaatc aaataaggca tagatttaga
    64801 cgcaggccaa gacctactct tatttgacta ttataacacc tcaaatacga aaagcatacc
    64861 cattcctcac ttaccaaggg taagcttaag aaatcattag aaacaggcat gcctttacgt
    64921 atcgttgata agccttgatg actacaagcg attaaaccaa gctcttagtg catcaaacag
    64981 actctctact gacttaaaat aattttttcc taccaagaat gagaccaact gctatgacaa
    65041 taaagcttgc tagaccgata atgatatggc cgcgatgatc agctttcatc tgctcctgac
    65101 tatgtttagc agccttagat ttagctttgg ctctagtctt agcagcctgc ttagaggcct
    65161 tgcctgtacc agccttagac gccttatgtg aagaaatcag gctcttaagc ttatctgtac
    65221 cggtcttagc gtcctccttg gcattactgc ttggagcagc tgacttctta gtcaaaagat
    65281 tggtcaaatt aggaatagca ggacttgtat gaccaccaat gatacctgtg tgaggctgca
    65341 agagctcacc tatggtacca tgtccctgat tgtcctctga gtgtggcaat tgtgccttat
    65401 cctttgtcag gctttgaaga tccaacttca taaagactgt ctggaagcct gttcccttag
    65461 agatagcgtc cataattggc acaaagacgc gaagaggtac caagccatcc tttttagcct
    65521 gatcaatcag cctaaatctc aacacctgtg ggtaattgct gccataagcg tctgacaggg
    65581 gcttgcctgt gacatctgta aagtaggaca caacctctgc tttttctgtc ttaccaaccg
    65641 gtctgccagt caaatccctt tggtagccat caacaaagta gctcaactct ccgagatacc
    65701 ctgtcaggtt accgatcttc atgcccttaa aggtcacctc taggctatag acacccttat
    65761 tcacaatcaa tttgacgcgg tggtcaatag cctgatgaga cattgattct gactgcaaat
    65821 catttttaag catgcttgcc ttgatgtagt agacaccatc ttcaagctta ttaatatcca
    65881 agcccttaga ctggtcacta cctgcaagct gatcctcctt gacctcaaca tcattagagg
    65941 tcagataaat atgctcacgc ttcttagcaa attccttggt gataagagcc ttacgaacac
    66001 gataaacacc tgctcccttt aggtcaaagg agccttgaag ctcatcttgt ggatcgttat
    66061 tcaagcgtct ctcatcaacg gtgacatatt gaccggttga tgtttttttc tgcaattgca
    66121 ccacaatatc ccagtcagca taacgctcat ttaataaggc aatgatgtct gacgagcttg
    66181 ccttaaggcg tttattgtaa tcctcaacag agctaatttc tgcttcggtg cttgagagtg
    66241 tctgctgctc ccaataatac aaatcaagca ggctaaaccc ttggtgatag gtcatcgctt
    66301 gatgatttaa agtcgcagat agattagcaa attgcttttg tgggtttagc ttatttgttc
    66361 ccatgatctg tctaagctta tcactaacgc cacttaggca gttaaactta agatcaagat
    66421 ccaatgcctt tagatctgca aaatcagctt cgctaatatt cgttaaaagg ttattataga
    66481 cattaagctt tgatagctgc ttattagcct tgaaggctcc ctgtgggatt ttagttagct
    66541 catttgatgc caagtcaacg gttaataagt ttggcatatg actaaagtca atattagcaa
    66601 tatctaaaac ctggtttcga ttggcaacga tataagaaag cttagttagc ttactcaagg
    66661 agcttggcag gctgcccaac tggttttcag aaacatcaaa gaagtttaga ttatcaagtg
    66721 aagctagagc attttctgaa aattcagtaa tgatattttc agccaaggcc aaggaggtca
    66781 agcgagatag accattaaag acaccatctc gaatcacgct gattctattt tttgacagat
    66841 ctagctgatc cagctgacca agatttctaa atagtccttc ctccagattt ggcatatagt
    66901 tgcttgagag atagagctct tttagctggc tgttatgagc aaaggtatcc ttatctaggg
    66961 ttgtaatcac attgctgcga agatttaaga accttagatt ggtcatttga ctgaaggttt
    67021 cctttggaat gcttgcaatc tgattgccct ctaagtgcag ctcagtaata tgcttagcat
    67081 gctttaagag tgaaatatct gtcaaatcat agtggtctag gcgcagctca ccttcaatct
    67141 tcgcaatttc ctcaggtgac attttgccat caccgttaag gtccttacca agcttaacca
    67201 aaaccttttc aagacgctca gagccgaccc ctttttcctt gtcgtcaatc tcagcctgat
    67261 agcctgtcca gcccttactt gctgtagcgc taaaggtcat gtccaacttg gtgtatttgt
    67321 catagtgatg taggtcgctt tcctgaccac ccatagctga tactagcaca gcacccttgt
    67381 gaagcttgtc cagctcctca atcggtaggg taaattcact ctaatgtagt tattgttaat
    67441 atcgcgttca ccaacctgag tgcggacaga ggttggatac tgccctttac tctcaatgga
    67501 aaagtcaatc aaaaattgcc ctagagctgt attgagcaat gaaatctcca tcttgccatc
    67561 ttctttgacg accagcttgg ccttcttatc aaatgctccc tgcagcattg aggcttcctc
    67621 tgtattttcc ttattggcct taaaggttaa ggtataggtt cctgccttta gatccgtaac
    67681 agccagatca gttccctgat aggacttgat actatccatc aaaagctcat aggtctcctt
    67741 gagcaatttt tcattgtcaa tctgacgata ggactccttg atcacctgaa gcttgctaga
    67801 caagtccttg acctgttctt tattggcctc gctagcaatg atacgctcag cttccttgat
    67861 cgcgctttcc agcttagtaa aatcaagtcc ctgcggtgct tcctgctggg atccttgtct
    67921 ctgcttttgc ttagcagaaa caaaggtgta ttgctcccct gactttttca ctgtaatgat
    67981 gacatcttca aagctttgtg aggaaatgac aaccttgttt tctccctcct tgaaagctgt
    68041 cgtcccaaga tgaagcccct tcaggtcaga cacatagcca ggcttgtcct ttactgaatc
    68101 atagaccaaa tccttatagt cctggtcatt gaccttgatc tttgtgattt gatgagctaa
    68161 ttccttaatt tgcttggtgc tggaatagcg atcaatttcc ggaaaaagaa gctctccttc
    68221 tgttgtctct agtttggtga taaatgatag ggtcgctaag ccatcatggc tagttacctt
    68281 agcaggcttt tctgtcttag cagcagcttg ctgcggtgaa gcagtagtat catctgaagg
    68341 cttggcagaa acaaaggtaa catcatttcc tttcttgtca aagaccacaa gaatgcctcc
    68401 gttagtctta ttgacgatgc gcagctgatg ctgtccttct gtgatgttct tagcgtttac
    68461 cttgattcct tggtaattga tgtcatagct atagtcaccc tccagctttt tgtcatactc
    68521 tttaccatca atgagaattt tctcgatatt tttataatag agcttcccct ctgacttgtc
    68581 cgcataggga ccgatctcct cgaacaataa aatattatcc ttaagcttga cagtcgtcac
    68641 aagacttgaa gagacttgag tagcctctga gcgaaccgtc tgggcagact gggcaagagc
    68701 cagcgttgat aaagcaagaa tggcgcactt attgatactt ttcattattt cgaaccttct
    68761 aaaaatgtta ttagccattt aattatttta ttaatctcac ttaatttatt atgttgtcaa
    68821 gcctttgtca agattgaatt tgagattttt ttcacaataa agcaaagaaa aaaacagccc
    68881 tgcaacagag ctggattttt tcttacaaaa attctgtact tctcgccttt aaagcaagaa
    68941 gattacttat gattttccaa caacataagt caattggttg gcctgctcag cagtaaaggt
    69001 gcggtatgaa atctgaccta agccaagaca atttgactct gaaatcagga tggagccgtc
    69061 ctttctgaca tcctcaacaa tagagacgtg cccataaaga ccgtcagcac ccgcttgacc
    69121 tggagcaaag gaaaccgcat agcctacctt tggctcctta gaaatactgt agccagactt
    69181 aaatctccag tcaccaccat ttcccataaa ggaatcaaac tgatagccta gctccttagc
    69241 gcgattataa acataccagg tacattgtcc ccaagcatag cttgacgcct gatagcttaa
    69301 aatatcatag ctcttagaca gcttgtagcc tgtaggaaca acagcaaagc ttgaagagga
    69361 ttgaattttc agctcagccg gaatctctgg cgtgcctcca tgctgatcaa tccaagcatc
    69421 taatttttcc atgatctcag cgcgacgctt gccaatgcca ttggtatctg tgaagtaaag
    69481 accaccatca ctagcaaagt tcaactgctt tttggcaaat ttatcagcct tttgatcctg
    69541 ctgctcaaaa ttaaggttgc tatttttgat aatcgtctcc tgtgtcagct taacaatagc
    69601 aagctcatca ttaaactgat ttggcttttt cgaatcaagg tcaaaaagcg catagccaaa
    69661 catgttagag cctagtaagg ttgcatttcc cttggttcct agctcacttt ctgtcattgc
    69721 aatggctaca atcgcccgca catctagccc actctttttt tcccattgca gcaaggcagc
    69781 accgttaatt cgcttctcat catacttgat cttggtagac tttaaaaagc tatcaagctg
    69841 ctctgccttg atcccatagc gcctagacaa gaggttatgg gtataagcac tctgaccact
    69901 ccaatgcgtc acataagcag cataggtatt tacagaaggc agggccagag tcaaggacaa
    69961 atcaactgta ggagcagcag gaacaatatt cagtgccggc tgagatgcct gtgtagcaac
    70021 ttcaggggct ggctgagggc tagctgctgg actagtaggt gtcgactgtc cagtagaacc
    70081 agaagctgat ccagagctag ctgtattgct tgatgacccc gttgctccag gttctccact
    70141 gttgggagta gtctcagtgg ttgatgagga gttgtcagta gctgaggtag cagctgctgt
    70201 cgaagtggac tcaccagtct gggcgattgc agcctcatta gcagtagctg gaacctggct
    70261 ggcttcagct cctgtatcct ctgccaatac tcttgcggtc tctaaatgag gtaccagaag
    70321 agtcatcagc attatcattc ttaataattt attttttctc atttagtatt caatcacttc
    70381 tttctgctct attctaacct acattataac attgaagcaa aataaaatgc aagatttttt
    70441 gtattaatgc cttaatactc ggataaaggt aagggccttt tctt
//
LOCUS       DARYMD010000003        65963 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYMD010000003 DARYMD010000000
VERSION     DARYMD010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 65963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65963
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TU818_000146"
     CDS             complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TU818_000146"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL0923015.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSGRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAVGFEQLIATSVRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRIYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVALTDTNASGEACQSCML"
     gene            complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TU818_000147"
     CDS             complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TU818_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL0923016.1"
                     /translation="MAARVMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNKANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVIKVQAILAGDEAL"
     gene            complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TU818_000148"
     CDS             complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TU818_000148"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL0923017.1"
                     /translation="MTQYYYDRSQSPIDYALSQTKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETIDDD
                     WEF"
     gene            complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TU818_000149"
     CDS             complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TU818_000149"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL0923018.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMLGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTGDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVRNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAIMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEIDYIKEQMTMSIAKPQEADWDPEKVALKSEKDTITFEAFD
                     AVEIRVAEVKEVSRVEGSEKLLRFRLDAGDGSDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGTIIG"
     gene            complement(6925..7623)
                     /locus_tag="TU818_000150"
     CDS             complement(6925..7623)
                     /locus_tag="TU818_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL0923019.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHCWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            complement(8009..9030)
                     /locus_tag="TU818_000151"
                     /pseudo
     CDS             complement(8009..9030)
                     /locus_tag="TU818_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515161.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            complement(9565..11244)
                     /locus_tag="TU818_000152"
     CDS             complement(9565..11244)
                     /locus_tag="TU818_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923020.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIYLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLNQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQEPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            complement(11419..16323)
                     /locus_tag="TU818_000153"
     CDS             complement(11419..16323)
                     /locus_tag="TU818_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL0923021.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGMGSVVAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLDD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADV
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRADLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKALTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAAGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGNGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASNFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLKDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAVGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQARVYKGTDTDRKELLWTSPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQTPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDGLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDINAQHQLSYSDNLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMSGHYRYVVSYLDA
                     NGMPQAEAYAVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSRVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSLGAAGSCQRQKKY"
     gene            16676..17503
                     /locus_tag="TU818_000154"
     CDS             16676..17503
                     /locus_tag="TU818_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL0923022.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(17579..17932)
                     /locus_tag="TU818_000155"
     CDS             complement(17579..17932)
                     /locus_tag="TU818_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL0923023.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSVEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(17936..18448)
                     /locus_tag="TU818_000156"
     CDS             complement(17936..18448)
                     /locus_tag="TU818_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL0923024.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVALIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLKRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(18905..19459)
                     /locus_tag="TU818_000157"
     CDS             complement(18905..19459)
                     /locus_tag="TU818_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0923025.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKSALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            19670..20299
                     /locus_tag="TU818_000158"
     CDS             19670..20299
                     /locus_tag="TU818_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL0923026.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVNRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGDFVYNDLELRAMEADILKAIEAGTDALVIGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            20758..21843
                     /locus_tag="TU818_000159"
     CDS             20758..21843
                     /locus_tag="TU818_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923027.1"
                     /translation="MTTRYFYKLLLTMLTLALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKADSLVPVETISRTQHKLFERESFKQAKQGYFAKTREGNDLKVLLTHIDQASL
                     EEKVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDRHLKKQAHKSILNQDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSNYYFLFPKRLYRYDC
                     SNHQMTCINLDQYGVTHAHALIAKPTP"
     gene            22029..23267
                     /locus_tag="TU818_000160"
     CDS             22029..23267
                     /locus_tag="TU818_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0923028.1"
                     /translation="MYESPEKIPYQLPLYDKYEGNNSLFRDNASPNFRADVKDITATL
                     VAVLSNGYPTGKSSFCKDYCPDEIRARQLTQLAIWYFTDGISEETLKSNYSLNDLEFQ
                     GLKYLIQAGKTAGTSNNRTLDIYISKDRNSKFQNLLGSTLVVKTPENKENCQCTKIYI
                     EENGKDGYYLYIYEDTNKNDKYDKNKDKLLQKKYIKNGKDGKPGLNGQRGPQGEPGKQ
                     GPQGPRGDKGETGEKGQDGKPGKQGDRGPAGPQGPRGDKGETGEKGDPGRNGKDGKPG
                     EKGDPGQQGIPGPKGDPGKDGEKGERGEQGPQGERGEQGPRGENPTPTPDPMPQPMPD
                     PAPKPESKPEPKPIPQPEVKPQPETKPQQPNKPSTITSQPSGKALPKTNDTGSLITVL
                     GTGLLSLLGLGFLTRRKRKQ"
     gene            23579..24874
                     /locus_tag="TU818_000161"
     CDS             23579..24874
                     /locus_tag="TU818_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0923029.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGAARVLAEQYYGYDDGTKDG
                     GDWPVFLYVTPTNHPERKTDKEHCVYCFNRLNSSPELWESQFKDPSKLGIKLPIYEKK
                     EGDESLLRAKSQKPSDNLTSKLVTVLSNGYPNKTLGNLSEDQSRRLTQLAIWHFTDGY
                     ATNHFKDGYHLNKDEDSELKKLIETAEKNFQTTAHTYSLNLYVTSSYNYSTGKFYQHL
                     LGSTLTPKLPNPNPGPKPPGGNNPHHLPGENGQTKYPEGESGEAGAPKKPEPKPEPKP
                     EPMPKPEPKPQPEPMPEPKPDPQPKPEPKPQPEPKPEPKPQPVPKPDPEPMPDPEPKP
                     QPEPKPEPQPEPMPKPEPKPQPEPMPEPKPKPEPQPKPAPQPEVKPQKPTKPSNTTSQ
                     SSGKGLPRTNEAGSLMTGLGTGLLSLLGLGFLTRRKRKD"
     gene            complement(25007..26125)
                     /locus_tag="TU818_000162"
     CDS             complement(25007..26125)
                     /locus_tag="TU818_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923030.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEEKAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKIALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSSLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(26122..27249)
                     /locus_tag="TU818_000163"
     CDS             complement(26122..27249)
                     /locus_tag="TU818_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923031.1"
                     /translation="MILFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPVFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            complement(27258..28181)
                     /locus_tag="TU818_000164"
     CDS             complement(27258..28181)
                     /locus_tag="TU818_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923032.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYESDFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDAHIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            complement(28204..28890)
                     /locus_tag="TU818_000165"
     CDS             complement(28204..28890)
                     /locus_tag="TU818_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL0923033.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYALVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            complement(28887..29558)
                     /locus_tag="TU818_000166"
     CDS             complement(28887..29558)
                     /locus_tag="TU818_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL0923034.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            complement(29533..30891)
                     /locus_tag="TU818_000167"
     CDS             complement(29533..30891)
                     /locus_tag="TU818_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL0923035.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYKELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPRVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKSNEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWKAFEPLISGEVRLSDLTNHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            complement(30904..31968)
                     /locus_tag="TU818_000168"
     CDS             complement(30904..31968)
                     /locus_tag="TU818_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL0923036.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALTKLR
                     YEDQQISTREIVKKLLQEES"
     gene            complement(31965..32915)
                     /locus_tag="TU818_000169"
     CDS             complement(31965..32915)
                     /locus_tag="TU818_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL0923037.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYQYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            complement(33143..33307)
                     /locus_tag="TU818_000170"
     CDS             complement(33143..33307)
                     /locus_tag="TU818_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL0923038.1"
                     /translation="MLQFASNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKA"
     gene            complement(33836..34093)
                     /locus_tag="TU818_000171"
     CDS             complement(33836..34093)
                     /locus_tag="TU818_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL0923039.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     gene            complement(34630..36669)
                     /locus_tag="TU818_000172"
     CDS             complement(34630..36669)
                     /locus_tag="TU818_000172"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL0923040.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVERMADFLKANRLSYDAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLVEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSIEDLVAKLAHVTFHEKIGSVAEHMERTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLTGEAAAVATAIREHYLPNSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPELLARAEALAA
                     ASQLDTYKPAVESLSRVFNLAKKAVDAVLIDASLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRRNRLALLAELVKKVETIAAFDRLNTK"
     gene            complement(37035..37946)
                     /gene="glyQ"
                     /locus_tag="TU818_000173"
     CDS             complement(37035..37946)
                     /gene="glyQ"
                     /locus_tag="TU818_000173"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL0923041.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     IFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            complement(38312..38845)
                     /locus_tag="TU818_000174"
     CDS             complement(38312..38845)
                     /locus_tag="TU818_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL0923042.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            complement(39112..39336)
                     /locus_tag="TU818_000175"
                     /pseudo
     CDS             complement(39112..39336)
                     /locus_tag="TU818_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(39366..40205)
                     /locus_tag="TU818_000176"
     CDS             complement(39366..40205)
                     /locus_tag="TU818_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL0923043.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTV
                     AQLALAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            complement(40292..41440)
                     /gene="nagA"
                     /locus_tag="TU818_000177"
     CDS             complement(40292..41440)
                     /gene="nagA"
                     /locus_tag="TU818_000177"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL0923044.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGYWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIEDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            complement(41557..43198)
                     /locus_tag="TU818_000178"
                     /pseudo
     CDS             complement(41557..43198)
                     /locus_tag="TU818_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            43389..44135
                     /locus_tag="TU818_000179"
     CDS             43389..44135
                     /locus_tag="TU818_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923045.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLIFSSLSPKPATITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHNQEDV
                     AIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPTPSPNP
                     QPNPQPETNTPSPQPPATEQSENTAPAGQN"
     gene            complement(44741..45583)
                     /locus_tag="TU818_000180"
     CDS             complement(44741..45583)
                     /locus_tag="TU818_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0923046.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLRFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            45715..46272
                     /locus_tag="TU818_000181"
     CDS             45715..46272
                     /locus_tag="TU818_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL0923047.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            complement(46683..47507)
                     /locus_tag="TU818_000182"
     CDS             complement(46683..47507)
                     /locus_tag="TU818_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0923048.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAQEGIKVVLCTGR
                     PQSGTRPYFEQLGLSDKEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATNLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLKLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAINQFALTKGS"
     gene            complement(47512..48126)
                     /locus_tag="TU818_000183"
     CDS             complement(47512..48126)
                     /locus_tag="TU818_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL0923049.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPKLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            complement(48287..49159)
                     /locus_tag="TU818_000184"
     CDS             complement(48287..49159)
                     /locus_tag="TU818_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL0923050.1"
                     /translation="MKKVMMSLLILATATLGACQASHQSDQPKQEQKEPQAKKGRLFL
                     SNMNSAKSQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWSQKQGNFIGTNCRINTFMLLKDSMTIAPTSSDDTLLFMDEDAITTSQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHFSAVSFNGPAKMLAVVIHDQLDGDYLF
                     IGHVGVLVEYKSKYLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVNLASYRS"
     gene            complement(49370..49855)
                     /locus_tag="TU818_000185"
                     /pseudo
     CDS             complement(49370..49855)
                     /locus_tag="TU818_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            complement(49858..50124)
                     /locus_tag="TU818_000186"
                     /pseudo
     CDS             complement(49858..50124)
                     /locus_tag="TU818_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106440.1"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
     gene            complement(50126..51058)
                     /locus_tag="TU818_000187"
     CDS             complement(50126..51058)
                     /locus_tag="TU818_000187"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL0923051.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARVYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            complement(51068..51583)
                     /gene="lacB"
                     /locus_tag="TU818_000188"
     CDS             complement(51068..51583)
                     /gene="lacB"
                     /locus_tag="TU818_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL0923052.1"
                     /translation="MKIAIGCDHIVTDEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGLADLGVCICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKADYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LDKWDRGDYHD"
     gene            complement(51599..52024)
                     /gene="lacA"
                     /locus_tag="TU818_000189"
     CDS             complement(51599..52024)
                     /gene="lacA"
                     /locus_tag="TU818_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL0923053.1"
                     /translation="MTIILGADAHGNDLKEAIKGFLQQEGFDVTDVTAIADDFVDNTL
                     AVARALKADEESLGIMIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            52160..52942
                     /locus_tag="TU818_000190"
     CDS             52160..52942
                     /locus_tag="TU818_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL0923054.1"
                     /translation="MLKRERLLTIMEKVNANGFITVTDIMESLRVSDMTARRNLDELA
                     RAGKLVRIRGGAQSISMPQKLERSNTEKLTVQIEAKKEIARYASQLINDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFTILNKSKTVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            complement(53358..53909)
                     /locus_tag="TU818_000191"
     CDS             complement(53358..53909)
                     /locus_tag="TU818_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL0923055.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRTQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(53922..54872)
                     /locus_tag="TU818_000192"
     CDS             complement(53922..54872)
                     /locus_tag="TU818_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL0923056.1"
                     /translation="MNENTKRLTDPIVLEKSRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLSLSSEYENIQDKLVKMYRLLDTLNHQL"
     gene            complement(55743..57974)
                     /locus_tag="TU818_000193"
     CDS             complement(55743..57974)
                     /locus_tag="TU818_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEL0923057.1"
                     /translation="MVKETYLLEGMHCTSCALAIEQAVKQLPGVEGAAVDVTTEKLSV
                     SYSTDSLSSAELIQAVRKAGYRAELLDETNMRGQLERLEEQASNEWYRFLWSALFSLP
                     LLYLAMGPMLGLVLPVALAPQSHAISYGLVQLLLTLPVLFLNRQYYENGFKALIKKRP
                     NMDSLVTLATSFAFIYSSYSCFKIVAGAAQFAHQLYFESVVVILTLITLGSYLEGRTK
                     GRASQAIQKLMSLRVTDVRVIREGALQLIPLEQVTNEDICFIQPGERVAVDGLIVEGQ
                     STVDESMLTGESLPVDKVTGDSVFAGTINGQGALRVKPSRLGNDTLLSQIIELVEQAQ
                     QAKAPIAALADRVSGVFVPIVLSLSLLSFLFWLFVMRESFDFALTIAIAVLIIACPCA
                     LGLATPTAIMVGSGRAAEQGILFKGGDILEKAYQVRTIVFDKTGTLTEGQAQLQRIIP
                     LAASEKQGLQEVASLEQYSQHPLGEALVRVAQEKGYDLLAVTDFQSLVGLGVTGVIDQ
                     HRLAVGNSELMSQQGIAISAAQTYAEQAALKGQTVVYYAKDNQLCALLLIADRLKADS
                     KAAIRALQDLGLQTVMLTGDNALTAQAIANEVGIDQVFSQVLPAQKAQIIADLKASGQ
                     LVAMVGDGINDAPALTLADIGISIGSGTDIAIEAADVILMTSAVRDVVECLELSRQTI
                     RVVKQNLFWAFSYNSLMIPVAMGILHVFGGPLLSPMLAGFAMSLSSISVVLNALRLRH
                     KKW"
     gene            complement(57974..58408)
                     /locus_tag="TU818_000194"
     CDS             complement(57974..58408)
                     /locus_tag="TU818_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL0923058.1"
                     /translation="MDTISDAEWEVMRVVWANGSMKSSEIIAILHEKHHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRRQLAMLRERLDGMCQRHHSRLLLALLKDT
                     PMTLEDIQAFQLLLEAKKVGAVSHVRCDCVPGQCHCQKKERI"
     gene            58638..59675
                     /locus_tag="TU818_000195"
     CDS             58638..59675
                     /locus_tag="TU818_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL0923059.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKNEDIKQPKDIILLS
                     PWLDVTLSNPEIPNYEASDPILSAWGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDITKFDGMLKQKGHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTIKKEYEPQK"
     gene            complement(59747..60097)
                     /gene="rbfA"
                     /locus_tag="TU818_000196"
     CDS             complement(59747..60097)
                     /gene="rbfA"
                     /locus_tag="TU818_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL0923060.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(60287..63157)
                     /gene="infB"
                     /locus_tag="TU818_000197"
     CDS             complement(60287..63157)
                     /gene="infB"
                     /locus_tag="TU818_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL0923061.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKNVQAGSAKDKQVAEQKAKAAKATTPQPAASKAAEKPAAATQEASQP
                     VAVKPKSRNFKAEREARAKEQVARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQ
                     NQQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDF
                     KARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAS
                     AKATESVASMAAASVAKPVDKRRKKQNRPDKGHDRDHGLEDGQKKNKKSWNSQNQVRN
                     QKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIKRE
                     PAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDSYL
                     NPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKI
                     TFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAIN
                     KIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEE
                     LKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTNDLG
                     RRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRV
                     SLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINE
                     SDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDP
                     EYQEKMLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLASLK
                     HYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEITRK"
     gene            complement(63177..63479)
                     /locus_tag="TU818_000198"
     CDS             complement(63177..63479)
                     /locus_tag="TU818_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL0923062.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAALGKPRKVVAIADAGFSKKMRTLMK"
     gene            complement(63472..63768)
                     /locus_tag="TU818_000199"
     CDS             complement(63472..63768)
                     /locus_tag="TU818_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL0923063.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAHVDHKVKRRELGLE"
     gene            complement(63784..64938)
                     /gene="nusA"
                     /locus_tag="TU818_000200"
     CDS             complement(63784..64938)
                     /gene="nusA"
                     /locus_tag="TU818_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL0923064.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTNEEV"
     gene            complement(65048..65530)
                     /gene="rimP"
                     /locus_tag="TU818_000201"
     CDS             complement(65048..65530)
                     /gene="rimP"
                     /locus_tag="TU818_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL0923065.1"
                     /translation="MNIANTAIIDIVTQIVEPVIKAPYELVDIEYDKMGNDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
BASE COUNT        19243 a        15762 c        12746 g        18212 t
ORIGIN      
        1 aatattttag aaatactata ggttattttg aatcttctga ttgttttgac agttacaaga
       61 aatcccagtg attaacacgg agacaagccc cagtaattat cgattgaaga gggagctttt
      121 ttcttgattc tccttaagca aatcagcaag cattggctta tccaagccaa atgtccttac
      181 aacaagcacc ggtagcccac ttcatttgac aaggggcttg tcagcaagca ttgatcacaa
      241 atcaggctga gctgcattaa gctcaagaga gcttgccatc agcctgttgg atcaagcgat
      301 actataagcc tattaacaaa ctggctagac agagcatgaa ggctgattgg tgctgcctat
      361 ttttaaggct aaaaaagatc taaagcatgc aggattggca tgcctcgcct gaagcattgg
      421 tatcggtaag cgctacaatc gtatcttcct catactgctc acttccttcc agaacgtcct
      481 gtctgacgcg aacataataa atggacgcac actttaactt aaaggcgtgt atataggcac
      541 ggttgagatc acgtgttgtt gcttggtctg tcataaatag ggttaaggaa attgcctgat
      601 caacgtgctt ttgagccgct gctacgatat taataatagg ctcaggccca acctcatagg
      661 caccacgctc gtaataagca tagttatcat cgcttatctg ataagcaggc acataaatcc
      721 ttcctaagtg cccctccttt cgcacctcaa ctggtgcaac aacaggctgt aagctcggcg
      781 tacatgagga caagtagctg atcgagccgg ttggtgcaac tgccatcaag tgagcattgg
      841 caaggcctgt ctcttgaatc gtcgcaacta attcctgcca atcagccaca ctaggcactc
      901 gaagcccgta gcgctcaagc aaggccgcaa ccttagctgt cttaggctta gcctcttttg
      961 tcaaatagcg ggcaaagtag ctgccatctg cataggttga ctgctcaaag ccagcaaatg
     1021 ctcccttttc cttagctaat tgactagaag ccttaaaggc ataataggcc attgtgtgga
     1081 aaaagagatc agtaaaatct actgcttcag ctgaatcata aaagatgtga ttggtcgcca
     1141 aaaagccatg taaattcatc gcgccaagac caacagcatg attagcagca ttcccctttt
     1201 caacagaagg agcgcagctg acgtctgagg cccttgacac atggtccaag gccctaacac
     1261 tagttgcaat caattgctca aagccaaccg catgcttcat ggcttcagca atattaatag
     1321 agccaaggtt acagcaaatg tcctcgccga tttgcttaaa ggtcaaatcc tcttcaaagg
     1381 tgcttgctgt gctgacctga gcgatttcag agcaaaggtt tgacatgaca atccgcccct
     1441 tttgtgggtg tggattgcgc ttattaaccg tatcatcaaa caagagataa gggtagccag
     1501 attcaaaatg aagctctgca ataagctgaa agagcttacg ggcactgata taggtctttt
     1561 taatggctgg gttggccact aggcggtcat actcctcggt aatggcaata tctgacatgt
     1621 ccttgccata aactcgctta atgtcatagg gagaaaatag cgccatgtcc ttattttccc
     1681 gcgccagctg aaaggtaata tcaggaatga caacgcctaa cgccagtgac ttgatacgga
     1741 ttttttcgtc tgcattttct ctcttcgtat ctaaaaaggt cagaatctct gggtgatgca
     1801 cattgaggta aaccgcacct gctccctgtc tttgccctag ctgattggca taggaaaagg
     1861 aatcctccag tagcttcatc actggcacaa tgcctgtcgc ttgattttca atgcctttta
     1921 tgggagagcc aacctctctt agattggtta aacacaaagc aacgccgccg cctcgttttg
     1981 agagctgcaa gctcgtacca atcgcacgcg aaatagattc catgttgtct tcgattcgca
     2041 gcaaataaca ggaaatatat tcgcctcgac gctttttacc tgcatttaaa aaggtagggg
     2101 tcgccggttg aaagcgcccg ctaagtatct gatcaatcaa atcccgcacc aaatcaggat
     2161 caccattagc caaaaacaag gcattcataa cagcacgatc ctcaaaatgc tctaggtatt
     2221 gtgacccatc tagggtttta agcgcatagg actggtaaaa tttcatggct cccattaagc
     2281 tcaaaaatga gaacttttgc tggtaagcgt aggtaaaggc ttcagtgata cattcagccg
     2341 aataagcctt taaaatctct tgatcataat aatcatgcgc caccaaataa cgccatttct
     2401 cctccaaact atcaaaggat aggctttgtg ggtagacatg ctcctctaaa tagcgctgaa
     2461 cagcttcctt atcactgtca aagtgatagg taccatctgc tcgtttaaag cgtgtaaggg
     2521 catttaatga gaggtaggac tctttttgtg acattctttt ttcctttcgt tacaatgtgt
     2581 gatcgttttt ctatcattag ttataaggct tcatcacctg ctaaaatagc ctgcaccttg
     2641 atgacatctc tttgtgtccc cagcaattca aattggtgca aaagcggcac ctgcaatttt
     2701 tgtgcaatga ttggtcctgc aatggcaaag gtatcaccaa agttagtatt gccagaggaa
     2761 ataaccccct tacagtgcct tcgattgtta gccttgttta gaaaatgaat cacctgcttg
     2821 ggaacagctc ccttgctgtc tgagccacca gcagcatagg tagggacaat caaaatataa
     2881 tcctcatcaa ctaatagagg ctcaccagtg actggaattc ttagagctct tacatctagc
     2941 ttttgcacaa agcggtgagt gttgttagat cgcgatgaaa aataaacaag cattaccctt
     3001 gcagccatct taaaactccc aatcatcatc aatggtttcc tcagtaactc ccatcacgta
     3061 agaagagcca tttcctgaga aaaagtcatg gttctcatct gctcgcgctg atagctgagc
     3121 aaatacctca ggggaaatac gtgtttcctc ctcagtaaag ggagaatcat accctagatt
     3181 ttgcaaaaat tttccagcat tatagacgct aaagcgaatc gcatcgtcag caagatcaaa
     3241 gccgtcatac aattccctca ggtaagcctt ctccaaatca atcagctgat aaagcagatc
     3301 aaacacaaag gccttcatct cagcctgctt ttcaggactt agggctgcca ccttttgttg
     3361 atacttgtag ccactgtaat aattgtgaat gaccttatct ctcaggatta agcgaataat
     3421 atctgaggta ttgggcattt tgcctctagc tgacaggtaa aaaggcaggt aaaagccacc
     3481 atatagcaaa aatcctggca tcatagctgc tgcgacctta gacttcagag ggtcatcacc
     3541 agtataatac ggaatcaaca cacgcgctcg ctcctgtaag ctctctgttg acaccaccca
     3601 atcgtgggcc tcctcgatct gctgactgct gcacagggtc gaaaagattg tcccatagga
     3661 cctagcgtga atagcaacca taaaggcaaa attagtataa atcacctgct catgatcggt
     3721 caaagaatgt tgaatttgtg ccacatctcc aactgttgct tgaaccgtat ctagcaaggt
     3781 caagccggta taggttcttg tgatgagcct ttgccaatcc tcccccaaag aacgccaaga
     3841 attaaggtca ttagaaacag gaaccttctc aggcagccaa aaattttgcg tcacacggtt
     3901 ccagacctcc aggtccttgt cgtcattaag ctgattccaa ttgacagagc gcaaactttt
     3961 tttggtttga gacaaggcat agtcaatggg tgactgtgat cggtcgtaat aatattgggt
     4021 catgttttct ccttcaagct tgatagtcgc aatatcaatc cttcagctgc caagccttct
     4081 acagctttag gactagggaa gactgctaag tgccacattt agacaacaca aaaagacttg
     4141 ctctaaaggg caatcctaca ggctaatgat aatttcttgc tgatgatccc taaccagtca
     4201 gcaactgctt tgtaagcaag gctaagcccg cttttttccc cggctgaatt aagtatactt
     4261 aattcttatg tttgttataa taacacaata tatagtgctt tgcaatcttt ttgatacaat
     4321 atatagatta atttatgaaa aagaaatcat aaaaggagct agcagcacct taacgaaagc
     4381 cctgtctgta tgctcaccaa tccctcatct gccaacttgc ttttcaaata agatcaatac
     4441 atatcaattc acacccccat gaagggagcg actagagcgt gagataaaga aacaaaaatg
     4501 atgtattttc aatactcaga gctttcactg ctgttattgc ctattaggct gctagactag
     4561 tgcttctttc ttgttcaaag tttacaaagc tcccacaaga agtctaggtc tcttgtcttt
     4621 ttaagacact aaaaatcccg tatgctcctg ctaatcaatc tattagcaag acccatacgg
     4681 gatattgtca tctaaaagcc caatcagcca ataatcgtac catttggcac tgccggatca
     4741 accgtcagca ctgtcagctt gccatcatgt tctgctgaca aaagcatgcc ctgactgata
     4801 tattttttca tcatttttcg cggcttgagg ttggcaacaa tttgcacctt cttgccaacg
     4861 agctcttgtt catttgggta ataggctgca atacctgata agatttgacg atcagagcca
     4921 tcacctgcat ctaatctaaa gcgcagcagt ttttcagagc cttcaactcg tgacacctct
     4981 ttgacctctg ccacacgaat ctcaactgca tcaaaagcct caaaagtaat cgtgtccttt
     5041 tcagacttaa gggctacctt ttcaggatcc cagtctgctt cttgtggctt agctatgctc
     5101 attgtcattt gctctttgat atagtcaatc tctgcttcca tatcaagacg agggaagatt
     5161 ggctctcctt tggcaacaac cgtcacacct gtcggaagat ctgctaaatc aagctcttcc
     5221 agatgatatt tggcaccgag acctagctgc tccataatag cagctgaggt tgtcatcata
     5281 aatggctgaa tcaaatgagc caccacgcgc agacttgcag ctaaatgtgc catcacactg
     5341 gctagctgct ccttactatc agctgctttg gcaagcaccc aaggagcagt ttcatcaatg
     5401 tatttgttcg tgcgtgaaat aatcgtccat acggcctcca aggcacgtgg gtaatcaaca
     5461 gcctccattt gcttgtggta ttcggaaata tgatcagcca caacctgctc cagatccgca
     5521 tcaaaagctg taacgtttct gacataagca ggaaccctgc cgtcaaagta tttattaatc
     5581 atggcaactg tacgattcaa aaggttacca aggtcattag ccagctcata attgatacga
     5641 ccaacataat cctctggggt aaaggtacca tcagagccaa ccggcaagga acgcatgagg
     5701 taataacgca gaggatcaag accaaagcgc tcaaccagca tttcaggata gatcacattc
     5761 ccctttgatt tagacatttt accgtccttc atgacaaacc agccatgagc aatcaaacgc
     5821 tctggcattg gtaaatcaag catcatcaac aaaattggcc aataaatgct gtggaaacgc
     5881 aaaatatcct taccaaccat atggaaaacc ctaccactcc agaacttatc gaagttagca
     5941 tgatccttct gaccgtagcc tagtgctgtt gcatagttta agagagcatc gatccagaca
     6001 taaacaacgt gtttaggatt tgacggcaca gggacccccc aggtaaaggt tgttcggcta
     6061 accgctagat cctccagacc tggctcgatg aagtttttaa gcatttcatt catacgaccg
     6121 tccggctgaa taaaatcagg ctgagcctta aagaaggcaa ccaatctatc cgcatacttg
     6181 ctcaggcgca aaaaataaga ttcttcagag acccattcga cctcatgccc tgatggtgcc
     6241 acaccaccaa tgaccttgcc agcttcatcg cgataaacct cagctaactg actttctgta
     6301 aaaaattcct catctgaaac agaataccag cctgaatagg tccctaaata aatatcatcc
     6361 tgcgccagca acctctcaaa tacagcagca accacctcct catgatagtc gccagtggtg
     6421 cggataaact tatcataaga gatatcaagg agcttccata gtgccttgac ttcctcagcc
     6481 atgccatcaa cataagcttg aggggataag ccggcttctt gtgccttatc ctgaatcttt
     6541 tgaccatgct catcaagacc agtcaaataa aaaacgtcat aacccaacat acgcttatag
     6601 cgagcaagaa catcacaggc aatcgtagta taggcagagc caatatgaag cttccctgac
     6661 gggtagtaaa tcggtgttgt aatataaaat ggttttttct tagtcatctt acgtcctttc
     6721 aaggctaatg aaacctttgt aatcagggac tagggcaata cccattccca agctgagtcc
     6781 tgtcagctat caactgacat tataccataa ttttagcata aaaaaatgat cactcagcct
     6841 attaactgat acctccccca taatagacaa tgacaaacaa gcagtcatca aaaattatag
     6901 gaggaggata tcaattagta gacttcaatc atttttcaat gatacctgat gatggtaaaa
     6961 ttcctgtgcc aagaggtagt tcacgtagca caatgggatc agcatgggag ataaggcata
     7021 ctcaccatag gatagtgata aaagagtaga acagaccact ccaagggcaa aggagaggat
     7081 aataatcaag gtattgcgac caatatggac tagctctttg ttgttctcat atagtccctt
     7141 tgtcaatagg taggcagcat ttttaatatt accagtcatc atcacattgg catagctcgc
     7201 accgcgcaag gttttaaagg tatctacctg aatcgaagca aaaaaagcta gagctgaaac
     7261 cgtaaaaaat gacgacaata agggtgtgag gattgctgtc acaagagcaa tcagggtcaa
     7321 gataaagcta gacaaaaggt accaatgcag accatgctta ttggcccagc agtgcataaa
     7381 gtaggtaaag gcctgcccaa tcataaaaac aatgataggc aataaaaatt gcagggcttg
     7441 gtcaaactgg cgctcagaca gacgaatcgc aaaggataag agattgcctg tctgaacccc
     7501 tgcaaagcgc ctgccttgcg tcatgtaggt aaaggcattg acataaccac tgataaagca
     7561 aagcatcatg gcgcacctta agccctcata tacctgatac gtttttcgtt tcctctttga
     7621 catacttgcc ttccttaatg tgattccaaa agaaaaatac tgacaaacag tatttgatgt
     7681 gattattagg aggataagct aagctcaatt gcccttgatc acagatagtc accaaagcaa
     7741 gttctgcagc tagactcggt aagtccccca aatacagctt tagtatagca taggcagtct
     7801 cttttatcaa gatgctttgc aggatcaact agcaccataa gactaaccat tagccaaaaa
     7861 gtactcaccc tctatgagga ccagcaggta aacctgataa aaaaactaaa aagccaccat
     7921 ttctgatgac ttcttagtcg gcctcttcaa caacttgtag cttacacaag ctatagcgct
     7981 aaggacagcc tttcattgga gcacaacatt agtcttcctt gcgttttgtt gacacaacaa
     8041 ccacacctgc acttgccatc actgcaagag ctgccgctgt gaagaatgga tgtgtcgctt
     8101 cacctgttga tggaagcttc ttagcttctt gcttaggtgc tggtttcttc tcttccttct
     8161 tagcttcagg ttttggttct ggcttaggct caggttttgg ttctggttta ggctcaggtt
     8221 taacctcttc atacacataa accacacgaa gatcgccttc tagggttgta ccagtttcgc
     8281 taggtgagcc ctcttgaagc ttcttgaact tgtagacctt accatctttt tcaatcttat
     8341 caagacgaag tgaggtagta tcgtacgctt cacccggcaa gccttgtgat accgcaacag
     8401 tttcacctaa aacattacct tctgtatcca cataagatac aagaacatta gcattaaacg
     8461 gaacaaattc ccaatcacca attaaagtaa tatctccatc acctggtgct gtatagccct
     8521 ctgtaagttt agtttcacca tcatttgtgt aacgtgacca accagtaaat ctccactcac
     8581 cagttgcagt tctgacattt tagcaacatc aagaagctcc tgtggtaaag tcataccttg
     8641 cttgctaccg aaaatgtaga taactgtact cttctcttta cgaagagctt cattagctgc
     8701 ttcttcttcg gcacgttttg atctttctgc ttctgcctta accgctatag tttgttcagc
     8761 ctcagctaag attttgttaa tatcgtcaac ttgaattaaa tttgaatcgt taattttcga
     8821 ttcaaaacct gcgattgttg aagccaattc cggatgctgt tgtttaagag tagttagacg
     8881 agctgtagcc tcagctttag ttgcatactt ctgccctctc attgttacct gtgccgatac
     8941 agaagctgta ccaactaaca aggtgcagaa tactgaagct agtccgaaag ccgacttacg
     9001 aagatagtac ttcatttctt tttttgccat ttttattccc ctttaaatat aatggacata
     9061 atgtctccta attatcaatg acagataatt acacttttat tataaaaggt attttctgtt
     9121 tagtcaagag aaaactgttt cttttacatt tctgttattt tacagttata tgtcacatct
     9181 gatttggttt aatttttctg aaaaaccagt agataaggca ttttaagcat tttttgatga
     9241 taagataata tcacaaaaca ttaattatat gacaattatt gtttttaatt attagaattt
     9301 ttaatcaaaa ctatcctgca atcagctgtt tagccatttt aaaaggcaaa caaaaaccat
     9361 gccacattgc aatgacatgg ttttcttcaa gaaaggagcg agctttggtt tggtactttc
     9421 tacaactgat ctccaatagc agctgctcct cgttagtccc tgagccacag gtgactgagc
     9481 tttcctgcgg ctactctgat agtaccagct actcttacaa ctgcataaag cagtggctgc
     9541 cagccaagct aaagctaaac aatattactc tgttatagct tggtctgctg acgagctctc
     9601 aatggtcatg tgattgaggt agttgtcatc agccagctga gccttaaact ggtctccgac
     9661 ctttaggaaa ggcagacggt cactagtttc actgcttgcc ttgattttat aaatctgacc
     9721 cttggaggaa atgtaataaa ccgttgttcc tgagataatc tggctggcca attgctccac
     9781 ctgcccagta atcatcttga ccttctgatc attggtgtct gacactgaca gcgagcttgt
     9841 gtccttatct gtgaattgtg agattaaggt ctgaatgtca ttattcactg ttacctgctg
     9901 ataatcctct gcatcaacca aggcatagga ttttatcaga ccagccccgt ccttcaatga
     9961 gataaggtaa taagccttgt catttaactt gactagggtt ggtgcagttg cagtgtattt
    10021 cttctcttga acttcgccct cggctgattt catggcagag gcctctgttg cagaaggcag
    10081 cttatagtta gtgacctctc tggtacgcat gttaaccaaa ataaagccga gatttgacga
    10141 atcagctgtt gctgaggtga ttcctgtata gaggtaaatg tctgagccga tggtaatgta
    10201 gttatagctg tctgttgttt gcttgacatc tgtctggcta aagacagtgt tccaatagcc
    10261 cttttgatag gtgtaatagt cattaaccct ctccaaaaca ttgtcagcag aatagacacg
    10321 atcaacccat tttggaacgt cctttagctc atagtattga gacttgccgc taaccgcgtc
    10381 taacaggatc acacccgtcg gctcctgaga ggacaggcca aattttgggg cgtaggttgt
    10441 tgcgacatag taagggttac catcgtcatc aacctcaaat gacgggtctg aaaaaatggt
    10501 catcgggtac tggaagcgca aatgcctcat ggtgtctcta aacataaatt ccgaatgaga
    10561 atacttcata ggctgattta acttgactag ctctgcctta ccagttgtct gattgacctt
    10621 gacataatag ccaatgccgt ccttacgatt ggttagccat ttccagaagg atttgtactc
    10681 caagggagaa acacgataag ggagcttgcc gatcgtaatc tgacggtact catcagaaat
    10741 accaaactgc gataccttat caatggtccc aagataagta tctccaatct tttcagccga
    10801 atctcgatcc agcaatgcca aggctgacag atcagtgtct ggaaaatcct tgttaaaatc
    10861 agcgtccttt accttaatca catgagcata ggacttagca cgaaacattc tagtattaac
    10921 agctaacagc aaggacaagc cagcaatgat aacagcaagg gcaagaccaa gccactttat
    10981 gccaccggtt aattgcttga gtgaaagacc tgaggtcacg tccttgcggc cagacttttg
    11041 cgtgaaaaag ctggtcactg tttttttcaa cccaaacaag gacaggataa aaagactcac
    11101 catcgccaag ataagcgcaa gaatcacgaa aaaccaaaat tctaagctca tcacgttcat
    11161 tggcggcaaa taaatccagt aaaagccagc caggatcaag ctgtctaagc caatcagcac
    11221 caaagaagca actttttttg tcatactaat ctcctcgtca caccctaagg ctatcagggg
    11281 tattcaatat cttctcaccg ctattgtacc acatttcccc tcaaaagatg acatctcagc
    11341 cagacatttt tatcagctct tagagcacct cagctagaat gatcaataca gctgacaggc
    11401 tacgctcata gagcttgctt agtacttctt ttgacgctgg caagagcctg ctgctccaag
    11461 actgagcaag cctagcagga ctagattgac cgctgcttgc tcacccgttg atggtaggac
    11521 ttgggctttt ttaactgctt gtgctgttag ggcagagcta gtgattgatg agccggtata
    11581 atgagtcaag cctccagcct gatgttctag ctgaggctgc ttagctttga taacctcaaa
    11641 ggtaagctca atcacgccat tatgtgatac ctctagacct ccttgaccga ttagctgata
    11701 gccctccggt agctcaacga ggacctcata gcttccttgt cgcagtgttt taccataggc
    11761 acttggaaca tagagagacg gagctagaga aatcaactga ccatttgctg ctttcaggct
    11821 gaccctgctg ccttctggca agacttggtt aaacaagagc caaacagaag ccacaatagg
    11881 ccttgtcatc tcaaaggcaa ctgaagcaag ccttgtatcc gcatctagac taaagctaac
    11941 caagttgtca gaccttagct caaacagatg attatcataa gccaagagct caacggtgta
    12001 gcgtccaaat ggcaatatca agctattagc tgagctattg aaatagtcca actgctcgat
    12061 tggcttgccc tgctcatcac gaataagata agtaaaggct ggctcttttt tgttctcaag
    12121 cacatcaagt gccaaggcaa cggacactac tcccttgtct ggtcctacag ctcgcaaagc
    12181 agctaagctc atataagcaa tctgacctgc ctcgtcttcc actagataat aataatctgc
    12241 ttctgcaacg ccttcaacct taggaatggt gtaggtgccg tctgcatttt gagcaatcat
    12301 caccttatta tccttgaatc tgatcagctg atcttcgaca gttagatcaa acttgcgtcc
    12361 atctttcttg acaaggtaga agacctcttc tctaacaata cctattggac tttgtccctt
    12421 gcttggtccc ggacgaaaga cctcagtagc accatcagct tggaagctag ctggcgtaat
    12481 gactggcttt tgatggctaa ctgtcaccgc ataggcctct gcttgaggca taccattagc
    12541 gtctagataa gaaacaacat agcgataatg tcctgacatc accctagctc ctgaggctct
    12601 tgtgccatac caagcggtgc tgtcaacatt agccacgctt gcacctggtt ggctagacca
    12661 gattgggctt gtcatagctg tatcctcctg ggcaaagacc gttaccttta gatcttgata
    12721 tacttgatgt ggcaagccct tgaatgccac aaaatccttg tttccatcat cattcggcga
    12781 gatgacagca gtttgaccta atttagccaa acgactctgt ggtctattgc ggctaataat
    12841 gagaagctct gcttcatttg tcaccagtcc tgtatctgca gcagtcatgt tgaggttatc
    12901 actgtagctc agctgatgct gagcattaat atcagttagg gtcaatgcca gctcagcctg
    12961 accgattttt tctggcaagt gatttcccag cttagcaatg gcaacattgc ctgcaaaatc
    13021 ctcgaccatg taataaaaat caccaagcgc cacctgatca actggcagga caaaagagcc
    13081 atctgctaag cgctcaacaa actgcttatt gtctgatacg gtcacatact ttaagccatc
    13141 attaatggta atcgtataag gcttgtcatc ctttgtttcc aagtaaaaaa cactatctcg
    13201 aagaacacca gcctgaccgc gatcaagcca ctgagacggt ctgaagcgat gggtcacagg
    13261 gttatagctt gctgttccta gctccggcgt ttgacgatcc acaatcacct caaagaccat
    13321 ttcttgacgt ttcgctccta ccacatctgg ataataagaa accacataat ggtatttgcc
    13381 atctggtagg tcagctccgg tcagcgattt accactaaag cctgtttcta acagcgttgt
    13441 tgacttggca aagcgaatat cactgttaaa gtttttatcc ccttgaaggg ctgatgggct
    13501 cgtccagagc aactccttac ggtctgtatc tgttccctta tagaccctgg cttgcaggcc
    13561 ttggtattta cgtaagaaca cccctttgaa ggcagcaaag tcttgattgt tgtcgccatt
    13621 tggagagata gccaacacag gatagccaac tgcatttcgc tccaacacaa atttaccgtc
    13681 tttattacga aaggttccta gtgtgtgcaa gccattgtca gcaatagtag tcatagagac
    13741 attggtatct gtaccaacag tcaccagccc agtaaaatga ttgccgacat aaatctcgtc
    13801 ctttagccct gagctgtcaa aataaaagcc agtttttcct tgagccttta gctcataaat
    13861 agaggcttca acaacaggta ggttttcaaa ggctccctta aagccaacaa atggaatgtt
    13921 gatgttatcc ttgtgctcgt ccttgctatc cacaaagcga acaaagccct ctagataata
    13981 gccatttggc atttgcttag agagttcctc tgtaaagttt gaggcatcta gggtaatggt
    14041 aatggtcttg tgtccttgag caggtacgtc aacctgttct ccctgatagg ttttcagaga
    14101 tcttgaacgt aaggcaaaac gtccttcctt agtatccacc tgatcagtca acaattctgt
    14161 ctggtagcgc agcgacttag cctgattaga caagttatgg attgtcacct caaagcttat
    14221 ctgatcagtc acatttccaa gagaaatact gccatagttg tctttacctg tcaggtacag
    14281 accactggtt accgcggtct ctatattcaa gagccctgct ccctgctggc gtggcgatgt
    14341 ggtggtattg gtcttagggt tgatgtggat ctgagcatta ctcatcagta tatttttgac
    14401 cagatctgct agcttatcct tggcaagctg tggttgaagc gcttctagat attgcttgac
    14461 caaaaggctt gcccctgcaa tgtgtggggt tgccatacta gttcctgact ggctgccata
    14521 gtgatcatcg ttgaaggtcg agtaaatatc tccacctgga gcagtgatgt caggcttcaa
    14581 atagccatct gaggtcaagc cccagttaga gaaatagttc atctcatttc ccttttggct
    14641 aatggcctta gagacctcag catcaaaggt cagagtgcct gttccattgc catttaaagc
    14701 agccattgcc atgccaaatt catgagagat aaaggcagat ggcagcacca tcccctttga
    14761 actcagacgc atggtgcggt tagccttgcc tggctcattg ttaaaaatca agaccccagc
    14821 tgccccgtac tgcttggcct ctgctataat atcgtcgtat ttccgattag gatcacgctg
    14881 caccaagaca atcttgccac tcacttcgcg ttcttggtag ccttcttttg tcaaagcttt
    14941 gacataaaca aatgagtatg gtacatcaaa gccaagacta gtcttaatgt ccttgaaatc
    15001 aacagattcc aaatagatag cctttccatg atttaagtca gccctatctt tcaagccctc
    15061 caccgtcatc agacgctcta taatcacttt gttattaata gacgcaactg aggtaggagt
    15121 ccggcctgct gatggagccc ccactaagcc ataatcagga tttgtcacca acgggtctgc
    15181 atgatctgac ccaaaggcac gctcattacc tgcagcaacg accacagaga caccagcctg
    15241 ccttgccttt tcgatagctg ccatcagggc acgattccca ttcaattgag acccattggc
    15301 cgagcccaga cttaaattaa tcacatcagc gcccaatgcc acagcatctt cgatggcttt
    15361 aataaataag gggtccccag ttcccatcaa atcatgggta aaaacccgca taaacatgac
    15421 ctgagcctca ggagcaatgc ctaaaaagcg ttcgccagct gctgccgcct tgagcccatt
    15481 tccagctgca atgcctgtca catgcatgcc atgcgattca tatttgctgt catcatctgt
    15541 atcttgccag tcaatgatag ttcctcctga tgtgtcatca agcttgatga ccgtttcctg
    15601 aggtgcctct attgactgcg gacggttcct cctaatatca atctgctgca caatcacatc
    15661 aaaatccaag tcgtcaaggc cctcaaacgg atcgtccttt atctccttta ccttatcatt
    15721 gttttccaca tagttgtggg caaagactac cttatcgctt agccagacac cgtactgaat
    15781 gcctgctgct tttttgcgct ggtcaatatc tgcctttgat gtaaacttag cagctgctgg
    15841 atttgtaatg cgcatggcat ggtgactagc gtcaatacca gtatcaataa cagcaataac
    15901 cttaccttga cccttatagc ctctattcca agctccttct gtttttatcc agcggtgagt
    15961 atccatattt actggaggta gctcgcgcga ttcttcttgc tgcttgactg attggttaga
    16021 ttccgttagc gcttccattt cggaagaaac taatccagtc gccattgcct cctctgtctt
    16081 ttcctctgct ttacttgact ggctgtcgat gtcctgagca ttaacagcag ctccctcact
    16141 agcctgagag acagacaata cctcccttga ttcttgatgt tgtcctgctg acacgtgagc
    16201 tgagctaact ccctgctcct cagccacaac tgatcccatc cctgtcagaa aaaggattcc
    16261 gatcaacaca gaaaccattc ctgatttata tttcctcagt gagaagcgtt cttttttctc
    16321 cacttgatgt cctcctagat ttattaaaaa aggttatttt aaacaaatga ttcatttatg
    16381 ttttaatcaa taatgtctaa gctatttaac cattttttaa tcacaaaagc aataagacta
    16441 gaagctctca gtttatgtca ttttttaatc attcaactca ctgaaatgag gcctctcaga
    16501 acctgtctca tcaacagata aggctaaact cagccgctag acttcaaaaa tgtcacacca
    16561 tttttagaca ttacctgtcc tcatacctat aacagaacca agcttccaca gtcgccttgg
    16621 ccttattttt ttgttacaat ataggttaag attatcattt agaaagcgaa gaaaaatgaa
    16681 actcatctca tggaacattg attctttaaa tgctgcgctc actggtgaat ctcctagagc
    16741 cctcttatca cgcgctgtac ttgatactct cgtggcacag gacgctgata ttattgcaat
    16801 tcaagagaca aagctatctg ccaaaggccc taccaaaaag caccttgaga gcttgcttgg
    16861 ctactttcct aatcatctca atgtttggcg ttcatctgtt gagcccgcca gaaaaggcta
    16921 tgccggaacc atgttcctct ataaaaaaga gctcaatccc attgtcacat tcccagatat
    16981 cggagctcct accactatgg acgctgaagg gcgtatcatc accctagaat ttaacgattt
    17041 ctttgtcaca caggtctaca ccccaaatgc cggtgatggg cttagacgct tggaagagcg
    17101 ccagctctgg gaccaaaaat atgccgacta cctagcccag ctcgatgccc aaaagcctgt
    17161 tttggctact ggtgattaca acgttgccca caaggaaatc gacctggcta acccagctag
    17221 caaccaccgc tctccgggct ttacagatga ggagcggctt ggctttacga acctgcttaa
    17281 ccgagggttt acagatacct ttcgctttat tcatggcgat attccaaacg tttatagctg
    17341 gtgggcacag cgcagcaaga ccagtaaatt gaacaatacc ggctggagaa ttgattactg
    17401 gctcacgtca aatcggttga ttgataaggt tagtcgctca gagatgattt cctcaggaga
    17461 acgtcaggat cacacaccga ttttattaga aattgatcta tagactagaa gcattcggac
    17521 aaatcaaccc agacattaaa aaaaaatggc tctgcaagag aaccgttttt ttaatcgctt
    17581 aaagacctag atccttatag gctgttcgat accctacctg caagacctga ttatcctgta
    17641 agaggatcgg ccgcttaatc agcatgccat ctgttgccaa aagctccgct gcctcctcaa
    17701 cgctcagtga attaacctta tctttaagcc caagctcacg ataacgcata ccactggtat
    17761 tgaaaaagct tttgaggcta taatctgaat gctctagcca ttgtttcagc tgctcagctt
    17821 tagggggatt ggccttaata tcaatgatat caacctcaga aaccagggtc tttagctcag
    17881 caagggcttt ttgacaggta ctacactttg ggtattggta aatggtaatc attagctact
    17941 ccttattaac actaatttgc tcgtgcctga gcaaccaggc cttcttttca agtcctccag
    18001 catagccaat caagcgacca tcagcagcca gtacacgatg acagggaata aaaatactta
    18061 aaggattacg tcctatggca ccaccaacag cctgagccga acgacactgc aggcgcttgg
    18121 caagctcacc atagctcaag gtctctcccc atcttatcgt ctgcaattct cgccagacag
    18181 ctcgctgaaa atcagtaccc tgtggagata agcaatcaag catgggatag ggcttcctct
    18241 caaagtaagc gtcaagccac aaacaggctc tttttaacag ggcatgctgc tcctgccaga
    18301 tgggctgcac tttaatccca gcctgaaaat acctttgacc ttcaaaccag gctcctatca
    18361 aagcaacatc agtcgcaacc aaggatattt ttcctaaggg cgattgatac acacactcgt
    18421 acaatggcaa gatctgacct ccccacataa tagcttattc ccttgactat ttattataag
    18481 aaaaagccta gctaaaggca agaaggagcc ctctgacacc acaacaaacg catgaaaaaa
    18541 caatagcggc tctttcaatg ctgccataca atcgttagtg tcaaaagtcg cttactatac
    18601 agctgccccc cttgaaaaac gaagctggaa agacacaaca tgctaaagct gtttcacgcg
    18661 ctggtgcctg attagatgtt cttctaatta aaggccaatg ttctgattaa aaagtcattt
    18721 catgcgctga tacctactca aataaaaaca catagcgtgg ggctagacca atccctcaca
    18781 agtcatcaat agttcgtcta tgagctacac tttatcacat tgggataggc agacatattt
    18841 gccggctcag ttgtacttgc ctgatagcta accaaaagcc cgataagctt tttccgatcc
    18901 tatatcaata gctgtagcgg ctatcctcgc taatctcctg ataagcggct ctttcatggc
    18961 ttttcttaat tttttgatag gctaagcgct cgccatcaat tggtaccttg ccacagtaaa
    19021 caaagcctaa cttttcaatg atatgccgca tgacctgatt atgctcatga gtatctatcc
    19081 gaaaatctgg tccatgctgc ccctcaatga gcccttgcaa aaaggtctga gcaattccct
    19141 gaccagtcct atcactcagc accgccacac gatgaaaggt cacataacgg tggtgattat
    19201 gctgccacct gccatcataa atcttgtcgt aggcgtcctc ttggccatca ataacagccg
    19261 cataagcaac aatctgcccc tcaagcaaag ccacatagcc ctgcccttgc aacacatcag
    19321 cagcaatatc ctgataagca ggatacccat ctgctttctg ccattggctg gagcctgatt
    19381 gggctaaggc agacttagct gaattgatca ctgtcatgat ctgactaagc tcattaggaa
    19441 aagcaagtct aatctccatc gttcacactc acaatctatt ctgatttgat gatgctatgc
    19501 taccgcaaaa agccttacac cttgtcactc tgctagggac acctcatagc ggtatgcctg
    19561 cttctcatct cagctgagta tagcacaata gtcatcattt gacaaaaagc ctcttcaagg
    19621 attgccagca atcatgctat aataaagtaa atcacaaagg agaaccatta tgattaaaga
    19681 attttgtgct gaaaacctaa ccatgctaaa ccaattgacc agccagtcgg tcaatcgtgt
    19741 tgagctctgc gacaatcttg cagtcggtgg caccacaccc tcttatggtg tcatcaagga
    19801 agcctgcgac ctcctacatg acaagcagat tagtgtcgca acaatgatcc gcccaagagg
    19861 aggtgatttt gtctataacg accttgaatt gcgtgctatg gaagcagata tcttaaaggc
    19921 tatcgaagca ggaactgatg ccttggtcat aggcttactc actaaggaca accagcttga
    19981 caccgatgct atcgaacagc tcctaccagc tacacaagga ctccctctgg tttttcacat
    20041 ggcctttgac ctgattgctc gcgaccaaca aatcgcaagc ctagagcagc tcattgacta
    20101 tggctttgta cgaatcctgc ttcatggctc aagcgatacc agatccatct atgaaaacat
    20161 tgaccatatc aagcagttag tcaaggctgc tcagcaccga atcgaaatca tgattggtgg
    20221 aggtgtcaca gctgataact gccaagagct aagtcaacta acaggaacag ctattgtgca
    20281 tggcacaaaa atcatctaac tatcagctca aataaaggaa aagtcactcc ctacaaggag
    20341 gtaaataata gcagcccttc tcgttgaagg ccatacctga gcccttagac taggctccta
    20401 gcaaactaat agtataggac cttcgctgcc tttacatcaa aaaggctgcc gtccagaaaa
    20461 agagaaagcc acacattgat agaaaaccat agctggctct actactatca gtatctatca
    20521 tcagcttctg agctgcctaa aagtttcggt gatcattaac aagtacagac tatttgtttc
    20581 taaattagat cataaaacag acaattatag gaagcgacaa gtgaatcatt attcattttt
    20641 tattgattac tatgatacta taagtaagga tagcgctttc tttttgtctt tgctttgcct
    20701 gactattagg ctctagattt attttttacc atactaatat aagaatcgga ataaataatg
    20761 acaacaaggt atttttataa gctattgcta acgatgttga cactagcatt aggaggattt
    20821 tccctatctg cttgccactc caagattagt aagccctatc aagtcgctat ttttgacaag
    20881 gatcatgtta ggacctttat ggaaaaagct gacagtctgg tgcctgttga gaccatctct
    20941 cgaacacagc acaagctatt tgagcgagaa agctttaagc aggccaagca agggtatttt
    21001 gcaaagacaa gagaaggaaa tgacctcaag gttctgttaa ctcacattga tcaagcaagc
    21061 ctagaagaaa aagtccttca tgctgatggc aatgacgcct acacctctac aactgatggt
    21121 gattactttt acacaacagc tgtctttgcc gatcgtattg actgctacaa gtatgaccgc
    21181 cacttgaaaa aacaggctca caagtctatt ctaaatcaag acaccattaa tgccagcaat
    21241 cagtttctgg tgattgatga cgctctgtac ctgcttgtca gcgctgtaga catcaagagt
    21301 cagcagccca aaactgagct atggaaaatg gacaaatcct ttactatcac tgatcggata
    21361 gatctggacg aaagcactgc ctatctgcgc atggtcaacg tcggacgaac cctttacatt
    21421 acccaggctg ctgatggcat tttagaaact ggagaaccta gacctggtaa caaggtgatg
    21481 acctatgact tagatagcgg tcaaaagtcc tatctcatgc ttcatgtcaa tagtcctaga
    21541 gccatttacc accatgccaa aaccaatgag cttatcatcg aaaatgatca gcattataat
    21601 cctgactttg catggaccat ctaccagcta gataccggag aggagagaac cattcgcttt
    21661 gaggagctag ccggtcagga gacaagctct ccctacttta tgatgacctc aagcaactac
    21721 tacttcctct ttccaaaaag gctttaccga tacgattgta gtaaccatca gatgacctgc
    21781 atcaacctag atcagtacgg agtgacgcac gcccatgcct tgatcgctaa gcccacacca
    21841 taaatcacaa caggcctaat caccactcat tcatctacac cccaatgctt agacaaagca
    21901 gtgtactgac ccccaaaagt tggacacgac atattagtga aaggatttag ttctgtattg
    21961 cacagggcta agtcctttca ctaatatgtc gtgtccaact tttgggggtc agtacacttt
    22021 gggaaagtat gtatgaatct ccagaaaaaa taccttatca actacctcta tatgacaagt
    22081 atgagggaaa taatagttta tttagagata atgcctcacc aaattttagg gcggatgtca
    22141 aagatattac agctacttta gtggctgttt taagtaatgg ttatccaacc gggaaaagca
    22201 gtttttgtaa agactactgt cccgatgaaa tcagggcaag acaattaacc caattagcta
    22261 tttggtattt tacagatggt atttctgaag aaacgttgaa atcaaattat agtctaaatg
    22321 atcttgaatt tcaaggatta aagtatttaa tacaggctgg caaaactgct gggactagta
    22381 acaatcgaac tttagatatc tatatatcta aagatagaaa ttcaaaattt caaaatcttt
    22441 taggttctac cttagtagtt aaaactccag aaaacaaaga gaactgtcaa tgtactaaaa
    22501 tttatataga agaaaatgga aaagatggtt attatcttta catctatgag gatacgaata
    22561 aaaacgataa atatgacaaa aacaaagata aactactaca gaaaaaatac ataaaaaatg
    22621 ggaaagacgg caagcctggc ctaaatggtc aacgtgggcc tcagggcgaa cctgggaaac
    22681 aaggaccaca aggtcctaga ggtgataaag gggaaaccgg agaaaaagga caagatggta
    22741 aaccgggcaa acaaggtgat cgtggtccgg ctggacctca ggggcctaga ggtgacaaag
    22801 gggaaactgg agaaaaagga gaccctggac gtaatggtaa agacggtaaa ccaggtgaaa
    22861 aaggggatcc tgggcaacaa ggcattcctg ggcctaaggg tgatcctgga aaagatggag
    22921 aaaaaggtga acgtggagag caaggacctc aaggcgaacg tggggagcaa ggacctcgtg
    22981 gagaaaatcc cactcctacc ccagatccaa tgccacaacc aatgcctgac cctgcaccta
    23041 aaccagaatc caagccagaa cctaagccga tacctcaacc agaggttaag cctcagccag
    23101 agacaaaacc tcaacaacca aacaagccat caaccattac tagccaacct agcggcaaag
    23161 cactaccaaa aacaaacgac acaggcagct tgataacagt attgggaaca ggcttgctct
    23221 ctcttcttgg actgggcttc ttaactagac gcaaaagaaa acaataatta aagcactatc
    23281 tatagctttt taatcattgg ctatcaaaca aatcacaaaa aagcttatcg ttttactcct
    23341 aacgataagc tttttcgtat tctctattac ttggtcccaa tactattttt ccagctttag
    23401 gctggttttg ttaatccaaa ataatatcag acaatttccg ttttaattaa aaaaaaaaaa
    23461 cgaaactgcg gaagctaatt atcagaaaat gattcacagc ttagagtcac catgttaagc
    23521 tattctacgg agaagaaagg tttgggaatg actatttcta aactcaaagg agagaaacat
    23581 gagaaaaaca atgaagaaga tgctagcagc ctcgacagtc tgcatcatca tgtcgggcag
    23641 ctttatcgga ggcgcggcaa gagtactggc agagcagtac tatggctatg atgatggaac
    23701 aaaagacggt ggagactggc cagtattttt atatgtaaca ccaacaaatc accccgaaag
    23761 aaaaaccgat aaagagcact gtgtctattg ctttaacagg ttaaatagtt cacctgagct
    23821 ctgggaatct caatttaaag atccaagtaa gctaggtata aaactcccta tctatgaaaa
    23881 gaaagaagga gatgaaagcc ttttaagagc taaatctcag aagcccagtg ataacttaac
    23941 ttcaaaatta gttactgttc tttcaaatgg ctatcctaat aagacattag gtaatttaag
    24001 tgaagatcaa agtcgccgat taacacagct agctatttgg cactttactg atggatacgc
    24061 tacaaatcat ttcaaagatg gttatcatct aaacaaagat gaagattcag aattaaaaaa
    24121 gttaattgaa actgctgaaa aaaacttcca aactacagca catacctata gcttaaatct
    24181 ttatgtaact tcatcatata attatagtac aggtaaattt tatcaacatc ttcttggttc
    24241 cactttaaca ccaaaacttc cgaacccaaa tccaggacct aaaccaccag gtgggaacaa
    24301 tccacatcat ttaccaggtg aaaatggtca aactaaatat ccagaaggag aaagcggtga
    24361 ggcaggagct cctaaaaagc ccgagcctaa accagagcct aagccggaac caatgcctaa
    24421 gccagagcct aagccacaac ctgagcctat gccagaacct aagccagatc ctcagcctaa
    24481 gccagagcct aaaccacaac ctgagcctaa gccagagcct aaaccacaac ctgtgcctaa
    24541 gccagatcct gagcctatgc cagatcctga gcctaagcca caacctgagc ctaaaccgga
    24601 acctcagcca gaaccaatgc ctaagccaga gcctaagcca caacctgagc ctatgccaga
    24661 acctaagcct aaaccggaac ctcagcctaa accagcgcct caaccagagg ttaagcctca
    24721 aaaaccaacc aagccatcaa acactactag ccagtctagc ggcaagggac taccaagaac
    24781 aaatgaagca ggcagtctaa tgacaggact tggaacaggc ttactctctc ttctcggatt
    24841 aggcttccta acaagacgca aaagaaaaga ctaagacact aaaagattat ctatagtcgt
    24901 ttagttgatc agtatctagt ctaatacaac acaaaagcct tatcgcgcca taaatggaac
    24961 gataaggctt tttaagcttg gttcaaaaag ggtaagacaa cttagtctag cgatgtaaag
    25021 gcttcatcag cacgcttgct agtaccatta aggtcatggc tgctacaaac aaggccaaga
    25081 aataaggcca agcctcacct agattaccgc cattttggaa agtgctgatg atggttaaca
    25141 cccaatgttg tgggagtagc tttccaatcg cctgcatata aggcggcgta atactaagcg
    25201 gccacaaaca acccgccagc atagaggttg gcatcacaat cagattagcc aattgactgc
    25261 tttgttgcgc atttttagaa accgcaccaa tcattaagcc aaagcctata gctaacaaac
    25321 tataaagaaa gaaagtcaac aaaacaatgg ctgttggaat gtaaaagctg acatttgcta
    25381 ccctgagtaa tcccagcata atcactattt gtatcgcaaa ggcaacaata ccaacacaga
    25441 catagctcag catgtattga aggcttgata gccttgataa gactaagcga ttgtagattt
    25501 gactggactt atcaagcaag ataccaccgt acaagacact ggtgctgcct agcattagga
    25561 tcaataaaaa gccagttgtt gtcgaggaaa cagacttact ttgggaacga tcagctaggg
    25621 tgatttcttt gaccttgtag gatagcttcg tgttatgagc tgaaatcttc ttgaaaacct
    25681 cttgattgcc tgctgccgca tcaccaatga tattgtaatt ctccaagaga taattagcct
    25741 gcgccttaaa ccattctgtt atttgactat cagcaatcga acgtagagcg atcttttgag
    25801 tgtctccttt tagaaccttc tcaccaaagc ccggctcaat ggtcagcaca gcctccagtg
    25861 tcttggcctt taggtattga tcaatagcct tttcctctag cctagtatat atctgatatt
    25921 ttttattgtg ctttaattgc gacacaaact gcttggaaac ctgactctta tccttatcta
    25981 agatcccaat cttagcttga cttccccctg taaagctcaa ggacaaggcc agcattgttg
    26041 ttagcatagg caacaggata aaggtgatat agcttgtttt tttacgtcta attttgataa
    26101 ataaggcttt aataaaagga atcatgctgc cacctgcttt ctcattctga ccaaagcaaa
    26161 gaggataaag gctgttccta taccaagatt aaccattaag gtaaccggta tgggattgga
    26221 ctgcccacca aaaataagat aaaacaaact atcattgacc cattttatcg gggaaatatt
    26281 agacagctga ttaatcaagg cgctatttaa ggttgacaaa ggaatatagc ttcctcccaa
    26341 aaaggcaaag acaggaatga ctgcattaga cgctaccgtc aaaaaggatt gatttctaat
    26401 accagtcgca agcccgatac cgatggcaac agacaaataa actagcgagg ccgtcacacc
    26461 gataatctgc cagtcattag tcccccaatt aacacgtaac acaaatcggg taaagacata
    26521 aagaatggtt agctggactg ctgttgctag cataccacca attaattttc caagcaaaat
    26581 agcactattt gagacccctg tcaaataaat gcggctagcc accccttgct gacgatctga
    26641 tagcaccaga ttcatcgctg acataatgct ataaaaggta atcatggtaa acatggaaat
    26701 agcatagtaa tccgctgagc tcatgccttt actggtttgc acagagctag aggcgatata
    26761 gtctattttt cttttcttga tgttgctaat ggcttctgga taaaggttag caatcgaatc
    26821 ataggtcttg gcgttatcca catagatatt gacaagcata ttaatcaaat cagcattctg
    26881 ttggttaatg ctgttggtgg tcacctcaat gttttggtcg ctcttaacct ctagagctgc
    26941 cgtcaaggcg ccctcgctga ccttttgctt agccttagcg atatccttgg tttctttagc
    27001 ttctaaatga agctctttat ttaacagctt taaaaacgtg ataaagttct tttgatactc
    27061 tgtttccttg ccctcaagct gataacgaac cgtcaattta ggaacagtag ctgctgtatt
    27121 aaagctggac ttaaaagcaa agcttaaaat cagaatcatc aagataggaa aaaccaccat
    27181 catcaacaaa gcagtccgat ccctaaaaat ctgtaagctt tcttttttga ttaaatgaaa
    27241 taagatcata acaaccccta atctcttagc ttcttaccag tcaaatgcag gaagatttct
    27301 tctaaattca aatgcttatg cctaatctca ctaaaagcaa tatgagcatc tgtcagctga
    27361 cgaacaaccg agccaatgtc ttcatgttca atcaggagaa ctgcttcaag ctcgttatcc
    27421 atcagtctcc aattgggctt attagagaga tcgattgctt ggtcagctgc gactgtcacc
    27481 atgatttgct ttgtgaaatc agactcatag cgtctttcta gctcggcctg actgccctct
    27541 tcaatcacct gaccatgatc cataatgtaa atgtaatcac ataaggcctc aacctcttcc
    27601 atgtagtggg tcgtgtaaat aacagtagct ccttgctcat ttaacaagcg aatagactct
    27661 aaaatatgat tacgagactg tgggtcaatc cctaccgtcg gctcatcaaa gatgattagc
    27721 ttaggagaat gcaccaaagc acaggcaatg tttaaccgtc ttttcatacc tcctgaaaac
    27781 tggcttggaa actggcttgc ctgtgatttt aaccctacga actccaagct ttttaaaacc
    27841 tgctccttga gctcacttcc ctttaagcca tagagagagc cgaaaagctc aacattctca
    27901 taggctgtta aatcaggata aacagcaata tcctgaggga catagccaat cttggaacta
    27961 atttttcgaa tagatttata agattgctgt aaaacagtca cttcgccagc attcaaaggg
    28021 attaacccta aaatagcatt gattaaggtt gacttaccag cgccattagg ccctaaaagg
    28081 ccgtagattc tcccttcctc aattgtcagt gagacatgat ctattgcctt tttgccgcct
    28141 cgatagacct tgacaacatc ttttaactct acaaaactca tatattattc cttctttcca
    28201 actctaacgc tgctctttaa aactaattaa cagataagtt aaggtcaata aaagcgaacc
    28261 aatcaaccaa ccatataata aggctgctgt cacacaccag acaccaatca cactaaagag
    28321 gcatagggct agtagctgct gtagccagcc tgagtaacga caggccttga ccaaggcata
    28381 gcccaaaacc acaagcgtaa gacctgccac tgaatctttt cctaaaaaga gacatagacc
    28441 taagtaacaa aaagcatcaa ccagtgtgac aagacttaac aaaagaaagc tagctgctgc
    28501 cctatctggt ttaaaggcta gccaagtcat ttttcctaag agcaggcgac tgtccttttt
    28561 cagcataaga tcaaaaagca agaccaaaac caacagggtc agctctacca aggctatgct
    28621 atacaatagc acataacaaa tgatttccca gccaaaggat acgcgaccca aaaaggtcag
    28681 caaaccatca agagctaaag catcagaaaa taatagacaa acaagcacta gaccaagctg
    28741 gattagacca agcaatagat caagccattg ctgataggac attgccctga tgtgccttaa
    28801 atgccatctg actaagcgcc gtcttttatg acttgttaga aaaagggtca ctaggattaa
    28861 aaaggatagc aatgctagta ttatgatcat cgtaccacct tcttatgcat tgattgaaga
    28921 tgactcaagc cttcaaccca taaattgcct ccaacatgaa caagcaacac cagccataag
    28981 ctctgactaa cataataaat acttccgtaa ataagaccag tcagtatttt ggcgtaaaaa
    29041 atggatctgc ccatcaggaa atggtttagg gcatagcaca ggctggtgat caacaagaca
    29101 agagcaattg gcaatcgcca ttgaagccac aagatgttaa accaaatcaa acgataggtg
    29161 atttcctcac agcaggccaa aaccaaggga tagcctatct gtggccattt ttgtgtcgtt
    29221 ccgacaaatg ataggactaa gggaagccac tctttttttt gccagcagcg gctaagatgt
    29281 aaaaaagcaa cctcaacaaa gagcacaaca aagctcaaga taaaaccaat gatcaaaaga
    29341 cgaccatcac tatgacctaa gggcgcttta ataggaggtg acagcaggta aatccctgtt
    29401 aagactaggg cataataaac cagtacagct cttaaaaaac ctattagatt aaagctatag
    29461 ctatcacgac cctggccaaa aatagcctgc attgcgatcg aaggacaaaa ggtagccatt
    29521 aaaaagcata ggttaaggca ttgggtgtac aaaggcattt gtcacacctc caaactgtct
    29581 catgcgtgga tgattagcaa atggaaaggc aggaatgcac atctcaagaa gctcaggagt
    29641 gaggacacgt gtcacgtacc agcctttttc tgaggcctca ggaggagtaa tgtctaaaaa
    29701 gacagcatta ggacttactt ttttagtgta ggctagtagt gtctttaaat cctctttttt
    29761 atctttccca gcatggtttg tcaggtcact aagacgaacc tctcctgaaa tcaagggctc
    29821 aaaggccttc catttaagct cctgatcctt tggatgagca tagtaaaaga cgttactatc
    29881 taggtctaaa aacaagggag agtcactctc agcattttgt gttgacgttg gattataaaa
    29941 caaattatag taatagctat agctaatagc tgaagcttcc atgattcctc ttaacagggt
    30001 atgcttagga tccaagcccg cctgaacccc aaataagaga taaggacctt cattggactt
    30061 gtttttaagg ataataccaa aggtataaag cggattatct tctccaacag tcatgtcaat
    30121 agggataatc tcataaagac tgtccttacc aagtctagcc tcttccaaaa gagctagaat
    30181 ttccggatca tcaataatca ctctgggaca aggcttttta gtatgccagc taagcatcat
    30241 agagtcgatt tgaatatact caatcaagct attacacatg gctgcttcca gcgttgtatg
    30301 agaggctgtc cccgttgaaa agcctggaat gatgtgcttt tcgcctacag cctgattggt
    30361 cttatagcca acgcaaagca tttgggcagg cacatacatc tccttatctt caaaaaacat
    30421 cggacactta acccagccca agacatcgtc ttgcgtcacc attttatcac acatgatcat
    30481 gtgcaaatca tggcaacggt caatttgttc ctgcgtaaaa acctgcaaat actctaaggg
    30541 catgacagga tccgtctggc tcaattcctt ataagaagca taaacaatcc ggtctgataa
    30601 taattcccca gcaataacag tggcataacg ctcaatgctt tcacctaagt atttgatcaa
    30661 ggcttcctca taatgactgc cataaccaat gatatgatag ctcacctgac tcagctcacc
    30721 aataaattgc ttgtggtagt caggcatctg tcctgtcaca ctctttaagt aaacatcatg
    30781 aggatggtta caaataggaa cctgagattg atttaagata ccagttcggt taccactaag
    30841 gccctttagc ttatcaagaa tatggttgaa cgaagggtaa taatgtagca tccttagacc
    30901 tccttatgac tcttcttgaa ggagtttttt aacaatctca cgtgttgaaa tctgttgatc
    30961 ctcatacctt aattttgtca gagccccttg tgtctgagaa ttagacattt tcaaaatatc
    31021 ctgcacctga atctcaagcg ttggcaaata gacacttaac aaacgccctt caaattttga
    31081 gcttcctgtt tgagcaataa taaaggcctc actgacaacc agattcatta acacatttaa
    31141 caaaggtaca taagaggagc taacaggctg tgttggcggc aactgctgac ttgcaaagcg
    31201 ctgataaagc gtgtgatcct gtaaacgtgc cagcaccctt ctctccaagc tatcaaaatc
    31261 agcactatga ggaggattta aggtacaagc atggataaac ggcccatcaa caaagccaag
    31321 caccaattgt tttttcaagg ccacactgat ttcattaagg tgacgcagca tcataatatt
    31381 caaccggcct tgacaaataa caatactctg atagtctgcg agcttctcag ataagcactt
    31441 catgttgcga tggtgctcca gagcatctaa gcgagaggta acatctgttt cttgaatgag
    31501 catttttagc tcatcgctag ccacctgaag gtttaagttc aggtgcttgg ccagcagctc
    31561 agcagattca ttgacatagc ttgaatcact gataaataag acaggtgcag tatccttagc
    31621 ctgtcctgat tcagctatga aatgataatt gcctgttaag accttcatga tattttcttc
    31681 aagagcataa gcgtcttcaa gcatcaatag gtcgttataa tacaaggctg tgatgacctc
    31741 tgacaatttt gcaaataagt cagactctag tgttttttcg taggtatcag tatcaataac
    31801 tttcccgtta aaccaatcgg agatgatact gtagtaggct tcttttaagg cttgtggctc
    31861 ttgtgcaatg tctaaaacag cttcattaaa atcccatagg ccttttctaa agcaaaacgt
    31921 atcgtcaaat tgcacaatgc gaacattgct atttaattga tatttcattg agactcctta
    31981 tttccaataa tcgtcatgtg aatcacatgc tgggtcaagc catccaagcc tagcttttct
    32041 tggaggtatt ccttattgta ccctccaata tcaacacttc catataccaa agctgttgag
    32101 accaattgaa cattttgagc aatctctcca gcttcaataa aggcataagc agtagcttga
    32161 tttccatatt tacgtgtgtt tttgatgtac tgataaacat agataagaat gacattgcag
    32221 ttttcggcag tgatcggtcc gtattcggca aaggctctaa tatcctcctg atcactaaga
    32281 tgatgacacc tcagcgcgtg ctgataagga aggtattcat aaaaaccgtc cttgagtgtt
    32341 tctacgtttc ttgcatagaa aaataaggtg atggggtaca gacccccacc agaagcacaa
    32401 tttcttaagg ctactgtctt agtcatgcct tctttgatga ttgcctgaga gctgacacca
    32461 caagcataat aaagcaaatc agccaaatcc tgcaaaggca tctcctcatc tataaactgc
    32521 ctatgacttc tccggttggt gatacaggtt gatagggctg ctgagacctt cttagcttta
    32581 ggaagtgcta tcgtgtttgc cctatcctca aaatagtcac tatttgaaaa ggtggtcact
    32641 gcagaatccg taaaaaactc agccacactg gtcttaaacc ctaggtaatt gttattagcc
    32701 ttgtaattca tcaaaaaccg ttggctaaga ttgtctgttt catcaggcat caaatgctgt
    32761 gccacaagct gttttgatgt ttttaatacc gtttgatgat gataggttga taacgataag
    32821 tgattggtat taaattcaaa taactgtcgt gcttcttctc ttgttaggtc actttggtta
    32881 tccgaacgtt gtttttcctt agaaaaaaat ggcataactg tcttcctgta atatattaat
    32941 aaataatagt aattagcagg taccgactag tacctgctaa ttactacaag acgttgacat
    33001 caagctgatt gtcttcgtct cttgtcatgt aacaccccta tccaacacca gctaacacca
    33061 tcaattacaa actgtaacct tagtcgctag caaactaatg attgtgacct agctattaac
    33121 tattaaatag aagtattaaa gtttacgctt ttggctcagc tgcaccataa ttgttgttta
    33181 tggtagtatt gccccatgaa gctgagacgc agcaacaaca agaacagcaa cagcagcaac
    33241 caccaggagc aacttgagtt gtttctgcta cactagtagc taaaatattt gaagcaaatt
    33301 gtaacataat gcttacctcc ttatatcgcc tgatcggtaa aacaaaacac tgataagagt
    33361 taaatgagaa tacctctcaa ctgatagcaa aagcaatcat gagcaggtat ccagcaacac
    33421 aaggctagct attttgtatc gcccttgtta aagtgaccat tcaattctta ccaactatat
    33481 tatattaaaa ttcaagacat atgtaaatac tttctttaat attttcttac aaaaatgtca
    33541 ttatttttcc agaaaggtta gcttattgag cttgacaaag tcttaagcct atctctttaa
    33601 tggcatttat aaactatcag tctttttaat gaaacgcatt aaaataggta gagatattat
    33661 tatctctacc taaactgtat tgatgagaca gatggctagt acctcacaat taaccatttc
    33721 taaaaataat gactcttttg tcgaaagacc taatgattaa agctatttgt ctttgtttat
    33781 ctttttctca ttagtaacat taaatcatgg caaaatattt atattcattt aataatcaag
    33841 attccggatc atcaagtgac cgtccatgca gacctttttc gcgctgcacc tgtcttaatt
    33901 tctcaggagt aacatcgttt ccgtcttcat caacaatctt aatgccttca atgtgatggc
    33961 gcactgagcg gcgatagccc tcaatgtatt cctcacgcag cttggcctgc tctacctttt
    34021 caggaccagt caagccaact gtttttttct tttttgcaag ctcgttaata cgagcgattt
    34081 ttttaggatc cataaatcac atataagggc tgcaccaaaa gcagtgagca gctgatgagg
    34141 cttgatgatg ggctagacag cctctttagg accgttacta ggacctttca agtccttttt
    34201 caccagctgt gccagcaagg gctgcctgca aatggggctg cctctaatcc tttctctttc
    34261 gtttgtgaca tagagtactg cactcttttt gtctatatct aaggctgtgc cagcagctgc
    34321 ttagccttat gcttctgcca agaaggctgt agcaagcttc ttgtgaaaag ctaaaatcca
    34381 tgctcacttt actaacagtg ttcctgatgc ttttattgac cactgaccag cacagctatt
    34441 gctagcaaag ctagcccaag acgatatctc gtagtaagca agaggactga tttgactaag
    34501 tatcaattgc ttgataagtc ttgagtgctt agggaaggac ttatcccaag gcaggtaatc
    34561 agtcacctat atcatctagg gaatacgaac agctaacaca gggcgatgtg cttaatctta
    34621 cacagcgaat tatttagtat ttaatcggtc aaaggccgca atggtctcta cctttttaac
    34681 cagctctgct aacagcgcta aacggttacg tctaatagct tcgtcctctg tcatgaccat
    34741 cgtatggtca aaaaagtcat caataactgg actaagggca aagacctgag ctagctgttc
    34801 tttggctgat ccagatagca ctagtgaatc aacagcctgt gccaaagccc tttcgtagtc
    34861 attttcaaag aggctagcat caatcagcac agcgtcaact gcctttttcg ctagattaaa
    34921 gacgcgagac agcgactcga cagcaggctt gtaggtgtct agctggcttg ccgcagccag
    34981 agcctccgct cttgctaaca gttctggtac aacaaagctt gagctagcca gaactgcttc
    35041 acgtatatcc tttggaatgg ctgagcccat cattttatcc acacgtgcac aaataaagtc
    35101 cagcacctca gccttatgct gataggtcaa gctatcaaat gacagctcat ataggctatc
    35161 aatcagctta tccataggaa tgctccagcc gaaatgctca agaattcgga cgatcccctg
    35221 agttgcacga cgtagggcat aagggtcatt tgagcctgac ggtatcaaac caacagagaa
    35281 aaaggacagc agggtgtcta gcttatcagc aagagcaagg acagcaccaa cctttgtttc
    35341 aggcagctct ccttctgccg aatttggcaa ataatgctca cgaattgctg ttgcgacagc
    35401 agcagcttcg ccagttaaaa gggcgtattt ctcccccata atgccctgca actcatcaaa
    35461 ttccccaacc ataccagtta gaaggtcaaa tttataaatc tgggcagcac gagcgacagc
    35521 acttttttct gcttctgaga gcccagcctg gtcagcaaga aaggctgcaa taaccttggt
    35581 ccgctccata tgctcagcca cagagcctat cttttcatgg aaggtcacat gagctagctt
    35641 agcaaccaaa tcttcaatag atagcttttg atcctcacgc cagaaaaatt ctccatcttc
    35701 aagacgagca acaagcacct tttcattgcc cttaatcaca ttttgaagat gcttagcatt
    35761 accgttacga acagaaataa aattcggcat tagcttgcca gcctgatcac gcacgacaaa
    35821 ataacgctga tggttcttca ttgaggttac tagaacctct tctgggattt ccaggtactt
    35881 gggatcaaaa cttcccatga aggcagttgg gtattctact aggttgagca cctcatttaa
    35941 gaggtcctca tcaatatcca cctgaacctt ttgctctgct tcgatggctc tgatttgtgc
    36001 tatgatcatc tcttgacgct ccttagcaga ggcaatgaca aattggctgc gcaggtcagc
    36061 ctcataggaa tcagcacttg taatgctagt ctcttctcca aggaagcgat gtccgcgact
    36121 gatacgtccc gaatgaatgt ctaaaaagtc aagctccaaa ggctcatcat ctaacagtac
    36181 aatcaagcta tgcaccggac gaatatagtc aaagctattg ttagcccagt gcatgctgac
    36241 tgggaaggtc aaggaagcaa gaacctctgg caccgctgct aagacgtcct tagcctgctt
    36301 gcccgcttca tgcttggtga cataaacgta ttcctcacct ttgacctctc ggaattcgat
    36361 gtcatcaaca gtcaagccct ttccacgaac aaagccctga gcggcttttg aaaattgacc
    36421 atctgcgtca agagcaattt ttttagaggg tcccttaaaa tcctctgtca gatcagtctg
    36481 ctgatcagct aagcccagca cacgcactgc taaacgacgg ggcgttgaaa agccttcgat
    36541 tgcgtcatag ctaagccgat tggccttaag aaaatcagcc atacgttcaa caagctgctt
    36601 ttcactaggt gtgacaacgt aggcaggaag ctcttcaaga ccaagttcta caagtaaatc
    36661 ttttgtcatc attaaaatcc tatgggcatc aaatctaaaa gagaagacca aaccgatcct
    36721 agcatgcctt gggcaagctt ggacgatcct ttgtctacaa gatttgtccc atctttcttt
    36781 cctttcttca agttatgggg taggtttagg agaccaaatc actagctcct aatcctgcaa
    36841 gcctgctaat aagctgcctg ttagacaaga tcacttagca gaaagactga gcttaacagg
    36901 actagtcatc aggcctttaa gtctcatcgc ttttaaaaag cacctaccag ataggtaagc
    36961 tgctagcagc aactagagct tacaagatca tacaagctgc attgactaca aggaactagt
    37021 ttagatccag ctgcttagtc ctctgccagc aaggctactc ggctagcatc atccaacaat
    37081 gggaagccaa gctttttacg ctctgcaaca aaggttttag caacgctacg agctaaatga
    37141 cgaatccgag caatatagcc agcacgctct gtcacagaga ctgcaccacg agcgtcaagc
    37201 aggttaaagg tatgagagca tttcaagaca tagtcatagg ctgggtggac aagcccttgt
    37261 gctaaagcac gctctgcttc tttttcaaat atctcaaagt tttcaagcag catgtcctga
    37321 ttggatacct caaaggaata cttggaatgc tcatattctg gctgaagaaa aatctcgccg
    37381 tacttaacac caggtgccca ttcgatatca tagaccgaat ccacctcttg aatgtatgag
    37441 gccaagcgct ctaagccata ggtgacctct gctgtcactg gtgatgttgc taggcctccc
    37501 acctgctgga agtaggtaaa ttgtgtaatc tccataccat caagccagac ctcccagcca
    37561 agtccagctg agccggttga aggattttcc cagttgtcct caacaaatcg aatatcatgc
    37621 tccaatggat caatgccaag tctttcaaga gattgcaggt aaagctcctg aatattactt
    37681 ggagaaggct tcatcaccac ttgaaattga tggtgctgat acagacgatt gggattttcg
    37741 ccgtatcggc cgtcagcagg acgacgagat ggctccacat aggcagcatt ccaaggctct
    37801 ggaccaatag cgcgaaggaa ggtataagga ctcatggttc ccgctccttt ttcattgtca
    37861 taggcttgca ttagcataca accttgatca ttccaatatt gctgtagcgt caaaataatc
    37921 tcttgaaagg taagtttgtt actcatgatt tcctctttct attttttatg tcttgtcgca
    37981 ggcgctaacc aagagctggc tatggcttga ctgctggttg gctcttaaac agcttttcaa
    38041 agagaaaaac cgcgcctata gccacctaca cctaaaggca taggggcgtc aaaacgcggt
    38101 tccaccctaa tttattactt catttgatct tgttgataaa cagatgtcaa gcaagctaca
    38161 aacacctgag cctactcttt agagaaagcg ccaaccagca gtaccatcac tcggctctca
    38221 ccagccccga gctcgcttta gatcagaaac ctgctatttt ctttcctatt ggttagttta
    38281 tcacaaaatc ctatgattgt ctaatcaact attatgattt tggacgagtt ccgtttggaa
    38341 taataacctc agacaagagc ctattttctt cacgaatgcg cagataaatc acaataatat
    38401 agcaagggaa aagcagcatt gccgtaatct gagcatggca aagcaaagca ataccaacca
    38461 gctctggagc aatgtttaaa aagtaattgg ggtgcttaac agtcttaaag agccaatgat
    38521 cgacatattt atggtccttt gccagcatca gcttcactgt ccaaatatct cccaagatcc
    38581 gagttacctc atatagcaca gctatcgaaa aaatcatcag cagcaagcca agaaagctaa
    38641 tgccatcaaa cttaatctgc ttgagcaatg cctctgtcac agcaaagaca taaatcatga
    38701 tatgcagcag ggtcaaaaac ttagtgtttt gcgcaccaaa ttccttgccc ccattagcca
    38761 ggatagcctt ctcgtttttg atcgattttt ttaagaatac taaacgaata gcaaacatca
    38821 agagcatcaa taacaggata atcaaagtaa gactccttta ttctagttta atctgtttct
    38881 ttcacgaaac actaattaag attatagcta agttacacag ccttgtcaaa ccgttttcaa
    38941 aaaaaagatg tctttctttg atctctaaaa acaagaggtc gtcacacagc accatcaaga
    39001 gacctcatca aagctttaag gtcgtaccaa atcaccatca aaagacagct cctagactca
    39061 gtcaattcac gagcagcaag cagcacccaa gaggcatttt gcaggcctga cctacttcgc
    39121 ctgtcgtaaa cacaaatcct caatatggta aatagcgtca cattgcgctg caacctcatc
    39181 gctgtgtgtt gccattaaga caatcatatc ctcagtctga caagctctga tggcttgtaa
    39241 gacctcctgc tcagcctcaa tatccagggc gcctgttggc tcatctgcca ataacagctg
    39301 cggtgttttg accaaagcac gagcaaggac cactaatgta gctcacttaa tccctgcagc
    39361 tcttgctaaa agtccttggt atcaggatct gggatagctg acatacccgg caggcaacga
    39421 atgcgctctg aatcctctgg actaatctca caatcaaaaa tagccatatt ttctactatg
    39481 cgttccttgt gcaccgactt aggtagagga ataaagccct cagcaataga ccaagcaagg
    39541 gctagctgag ccactgtctt gttgtacttt ttagccaatg cctgcatggt atcatcggca
    39601 aatatctctc cttgtcctaa tggaccccag gcctctagca aaatgtgatg cctgcggcaa
    39661 taatcaaccg tctctttttg atagcagcca ggcgccaagc gaatctgatt gactgctggt
    39721 gtaatggttg ctgtctgttt aagagcctcc agatggtgaa ccataaagtt gctgacacca
    39781 atcgagcgaa ccaagcctgc ttcaacagcc tcctccatat aagaccaagc tgctgcattg
    39841 gctgcttgcc agcaatccct aagagcctta ggatttggcc aatgaatcag ataaaggtct
    39901 acatactcta gtccaaggcg ctcaagagag gctgctaagg ctgccttagc gccatcatag
    39961 ctatgagcat cattccagag cttagtggta ataaagagtt cttcacgagg aacgcccgaa
    40021 tcccgaatgg cctgtccaac acttttttca ttgtgataaa tggcagctgt gtcaatatga
    40081 cgatagcctg ccttaatcgc tgctagggtg gattggtagg cctcctcacc atcagcagcc
    40141 ttaaaggtcc caaagccaag cactggaata gcaagaccat tagccattgt tactgtttta
    40201 atcatatcta aaacctcctt tttcattgta gcacaatgat aagcaaagca aaaagaattg
    40261 agctgatcac cagcccaatt cctttgctgt attaagcctc aaaggccttt tgaccattta
    40321 ggtaggttgc tactaattct aagtccttat caagaacaat aaagtcagca gcatgacctg
    40381 ccttgatttg gccacagaca tcttcaatac caaccgaagc agctgggacg taagaggaca
    40441 tgtgaattgc ttctgctgga cttgcaattc cccaggcaac aacattttta atgccgtcct
    40501 ttaattttaa gatagagcct gctagattac cactatcctt caagcgagct gtgccatttt
    40561 ccacaataac cggaaactct ccaagcatgt aatcaccatc tggtgaaccg cctgcacgca
    40621 tacagtccgt aatcaaagcc acatgctcat gacccttttg ctgcatcaaa atatcgcaag
    40681 caacaggtga gacatgatga ccatcgcaga tcagctctgc aaccgttcca ggaatattat
    40741 aaacagcccc aaccatacca ggctcacgat gagtcaagcc acgcatccca ttgtaggcat
    40801 gaacccaaac actagctcct gctgctactg cctttttagc ctcagtatag gtaccatttg
    40861 agtgacctaa agctactgtg acaccctgct tggtcacctc agagacaaat gcttctacgc
    40921 catcacgctc aggagccaaa gctatttttt tgatcaagcc cttagctgct ttttgccaag
    40981 ctgcaaattc gtctaagcga ggatttttca tatatatcgg gttttgggct cccttgtatt
    41041 cctcagtgaa gtaaggccct tcaaaataaa tcccctgaat ctttgctcct ttgacctgat
    41101 cggcaacaga agcaacggtt gcagacacct gctctagatg ctcaaaggtt gacgttaggg
    41161 tagtcggtaa gaaggaggtc actcctgttg ataagagacc ctcactgatg gcatggagac
    41221 cttctgctga attatccatc acatcagcac cagcatagcc atgaatatga gtatctacaa
    41281 gtcctggtgc tatttgatag cctgtataat caataacctc tgcctgatca tcaacagtag
    41341 ccgtccaata accaaatgtg ccattattta gctccaaata gcctgctggc tttacctcgt
    41401 tggggtaata aaagcaatct gctttaatat agcttgtcat cttttttcct ccctttttcg
    41461 tttattatac gccttaattc ttattttgta aatggtatat accagtcctt ctgttaaaaa
    41521 gaaaaacctg aatactattt caagttttcc cttttattag agctgtcctg aaagtacttt
    41581 ctcagctaga tttagggcgt ggtcagtgat acgtgtgtaa tgagatataa tgtcaataaa
    41641 attaatccct gcctgtgctg tgcattcgcc acgattgagg cgttcgatgt gtgttttacg
    41701 caattgacgc tctttttgct caatcgtcct atgacgctca acaatagact gggctagagc
    41761 cttgtcacta tccacaatcg ccctaatcgc atctaaagtt aaacagtggg tcaggtgata
    41821 catttctgtt aattcaccac gtgcagctgc tgaaaagcca atctgctttg ctgtaatccc
    41881 ctcaatgaga gtcgctaacg actcagagtg gtcaccaatt cgctccaaat cacgagacga
    41941 atccaacaga cctgctaaaa cctcattttc actaggacta agggcttcat tggaaatatc
    42001 aacgaggtaa gtggtgagct cctcatcaat cgtattgacc gccttctcat atcgcctcac
    42061 cttttcgcca aacttgtctt ctgctgtcat aatgtagcta taagacgcct caaaagcctg
    42121 aatagcatag gaagccagat gtaccaattc cttgtgggca tttcccaagg caatagaagg
    42181 agcctgagtg attagtaaac ggtccaaata caaggcttca tatttgacga tttcgtcttc
    42241 acctggaatt aaggtggtca caagctttgc cagagtgttg ataaaaggaa gcagcaacag
    42301 ggtatttgtg atgttaaagg tcccatgtga aaaggcaatg gtcatctcag gtgacagggc
    42361 caaaacagac tgaagccata gcataaagga ggtaaatggc atcagtaaaa tcataaagat
    42421 gaccgtccca ataacattaa aaagaatatg agcagcagca acacgcttag ctgcaatatt
    42481 agagccaata gctgccaaaa ccgctgtgat acaggtacca atgttagagc caagcaaaat
    42541 aggaatcgca ccctgcaggg tcaataggcc acccgaaaaa agcccctgta aaataccaat
    42601 aatggccgcc gaggattgaa tcagcatggt caatgctgtc ccgataaaaa caccctgaaa
    42661 gggcttgtct ccaagcgtcg ctaggtaatg ctgaaaggct gagactgatt ttaaaggatc
    42721 catcgcatca cccatgaggt tgagagaaaa gaaaattcct cctacaccaa aaatgatacg
    42781 acctaggtta ttgagttttt tatttgacgt gaaaaagaga caggctgctc caataaaaat
    42841 catgggcagg gcgtaatctc ccagcttaaa accaatcaaa aaggaggtca ctgttgttcc
    42901 aatgttggcc cccatgacaa taccaatcgc ctgctgtagg gttaaaaggc ctgcagatac
    42961 taggccaact gtaatcaccg tcacacccga gctagactga atcaaagcag acatagctat
    43021 tccaaccaag ataccaaaga aggggttgct tgtgtacttg tcaatgtaat acctaagctt
    43081 atcacctgcg gcctgctgca agtcgtctcc catgtatttg atactgaaaa gaaaaagacc
    43141 taagccctgt actgcccccc aaaaaatgaa acgcaatgtc ttgccaattt accgacacaa
    43201 tattgtcctc actcgcttat ttattctctt ctattttaat gtatttattc agttatcaca
    43261 agggtttttt aatcctttta aatagtgctc atttagaacc tattttagag ccctagtcct
    43321 cttttcattt tcctatattc agggtataat agtgctactc aagcgacaat gatttcaaag
    43381 gagataccat gagaaaaccg acaaaagaga cccactacct catcattagc ttgcttacta
    43441 ttgccattgc aggaggggcc taccttattt ttagtagcct ctctccaaag ccagctacca
    43501 ttaccaccca atctaagggc tatgagctgt taactaaggc tcaagcatta gtcaaggagg
    43561 ccgaagacaa cccaactaaa gaagctatcg caaaggctca aaaagcaatt aatcagctaa
    43621 aaaagaccca gtctaaggag gaattacagg ctcgactaac agctatcagc ttaaagcaca
    43681 atcaagaaga cgttgctatc aaggtcctaa aggcagccga ggacaatcca agccctgaac
    43741 ttaaggaggc tgcacaaaaa gccattagta agctctctga tgaggctaaa aaagctgcct
    43801 tacaggctag acttgacgct attggacttt caaagcctag cactgcacag cctgagactg
    43861 caacaccagc agcagaaaaa aatatagcac cagctcctgc ggctccacaa ataaagcata
    43921 ccacaccgtc ttctggggga acgacgccag caccgaaccc taaacctagt cctaagccga
    43981 atcctcagcc tagtcctagt ccagctccag agaacccaga gccaacgcct agtcctaacc
    44041 ctcagccaaa tcctcaacca gaaaccaaca cacctagccc tcagccacct gcaacagagc
    44101 aaagtgaaaa cactgctcca gcaggacaaa actaagaaag ggcagccaga gctgctgtag
    44161 cttagttaca cttcttagta caggcaataa gggcttagct actgaaataa tgctaaactt
    44221 acgactaata agctctctga taaaaagagg ctttaggtga ttaaaaacag ctggttctaa
    44281 aaggattcca gctgtttttg tgcttcttaa ttgattttga ggtaggaaga gaagggaggc
    44341 ttaatcaagt cgataagtaa tcccatatcc tctcctaact ctctatcagc ttggctatga
    44401 ttatagagcg gctcaccctt acgcgctttg gtgattcgtc atggatattc tgactggctt
    44461 gaccatttga gttttttcct cagtgtcact ccctaagact tttaagggac tgacgaggtg
    44521 attagcatgc acaacaaaaa gcccttaaac acacctttaa ggaccttgta ttcagcttaa
    44581 tgcctctata gtatcaggga tatttgttaa ggcagctctc agctaaagac ttgtgataaa
    44641 gacctatgcc tatccgacca ctagctagag tcaagctgtg catagctcag cctctatgac
    44701 taacagaaac cagaggcagc gttagatcac tttgcttagc ttaaacctca tagcccatga
    44761 gaagcccttc agcttctgca tagaagctgc ataggcctga ggctgggctg gtttgaatct
    44821 ctgcttctgg gtaaatcgct ctaatttttt ccgcaatttg ctcacagatc ttagggtttt
    44881 tggcgtggga gataaagact cggcctcctt tatagcctgc cttttgaatc tcttctaaaa
    44941 cagctgacac tgcctttttt tgacctctgg ccttttgaag cagctcaagc gtgccttcct
    45001 tacttgcctg tcctaccatt ctgatgttta ataagccaat caccttacca atgagcttat
    45061 tcagacggcc atttttaacc agattatcaa ccttggccaa cacaaaaaca agcctggttt
    45121 tttcctgata agctgtaatt ttctcaacaa cctcatcaaa agaaagcccc tgattgatca
    45181 accgctctag ctctaacaca atcaaatcca tctcaccacc tgctgacaaa gagtcaatca
    45241 catggatatt ggcattcgga ttttcctcaa gcaagtcatt ttgagccaat ctagcactat
    45301 tgtgactgcc tgagagcgta ccggtaatgg taatggcaat gacgttatct gctcccctgt
    45361 aggcttgtaa aaaagcatca ggacttgggc agcttgaggt tgctggctta gaggactgat
    45421 acatagtctc catcatttga tcaatatcta gaccatcatc atctctaaaa atatctgaac
    45481 caatctgtag ggttagcggc acacgctcaa agcgcaggtg attggattgg ctttttaggg
    45541 ctctaatatc gcagcctgaa tccgatacaa ttttccaggt cattcgtttt cctcttttcc
    45601 ttcatagtct gttttggttg acaaagtaag cattttccca taaaattata tcatcactag
    45661 ctagactttt gctagctaaa cgacatcaga tgtaacactt gaaaggtatt tgtaatggct
    45721 ggtaaaccaa tttctaaaca gtcccttcaa aatttagccc actgcaatca ggaatccaga
    45781 cggttaacac gagaagctat tgaaattgct ctgcttagct tactagaaaa gaagccctta
    45841 ggacacatta ccatttcaga attggtagct agagctgggg tttcaagaaa tgctttttac
    45901 cgcaattaca gctcaaagga ggatattctt gagtgtctgt tgacttctgt tatcagacgt
    45961 atctttcgtg gactgaaggc ctttgatcta aagacacagg cctatcaggc atggctttat
    46021 ctgtttacag aggccaaaaa agaagcgacg ctacttagta ttatctttaa ccatcacctg
    46081 cagcagctct tgacgcagat ggttaccaag cgtttgagag cctaccaaaa gtggcaggaa
    46141 aaaaagctgt ctcactacgc actgctcttt tggagcaacg ctattgtctc agtcctttcc
    46201 aattggattt ctgatgatat ggttgttcct gctgaggaga tggctgctat ggggctgccc
    46261 ttattagcct agttgtctct agatcaccta tagctcctag acaacttccc aagaaaccaa
    46321 gcttgcagca tcagacagga cgcttggctg gcttgactta agcactggca ctgcctacca
    46381 agatatgtac tagccctact acaggcaagg tgtgacttgt cgctcgctgt tgtgcagagg
    46441 cttaaaggct cttacattta gctggacaat aaaaaaagac tgaagaggct ggctggatta
    46501 gcctgctctt caatccagaa cctcctttgt tggaggtttt ttcgtgtttt atttttcagt
    46561 cgatctcaca cacctaggct tgtggtgttc caagacagct cagctctagt caacacctct
    46621 aaaactgagc ttatcatctc tagcttttgg aggccttttc tgacgggctg gtttgactgt
    46681 gcttaagagc cctttgtcaa tgcaaattga ttaatggcat gggccacgcc tgcttgatca
    46741 ttggagaggc ttaccttgtc agcgaccttt ttaattgcct catcagcgtt tcccatagcg
    46801 acacctaagc cagcataggc taacatttca agatcatttg ctgcatctcc aattgccatc
    46861 acttggtctg ggcgcagctt cagatcagcg gttaattcct tcagggcaga ggccttggtc
    46921 acacactccg gcattacctc taggattgtt tcttgactgc gaaccacact aaagcttgcg
    46981 ctgagttttt ctctaacaag agcctcaaaa gtatctaggg cagccttttc tcccatgtac
    47041 atggcctgaa atatgatttg actgctgttg gataactgag ataggttagt agcctttacc
    47101 tttgtaaaaa ccaaatcacc atcagcctga accatatctg gaaccttgct atctatcaca
    47161 agataatcac gctctccagt cagggtgagg taaatatctg aaaagggctg agacagctga
    47221 taaaggtgct caatagctga aaaggtcagg ctttgataat gtagcagctc ccagcttggg
    47281 ctcctatagg tgctacagcc attgtttaaa ataaggtact cctccttatc actcaagcct
    47341 aattgctcaa aatacggcct tgtcccagac tgggggcggc ctgtgcagag aacaactttt
    47401 atcccctctt gtgcagctgc ttggatagcc ttaatattct cttttggaat gtgctttttg
    47461 ctatcaagca gagtaccgtc taaatcaatt gctataagct gaatcatcgt ctcagtcctc
    47521 tttccatttt atcttaggta ggtgccattg tcttttgttg ccaatcatac gcatgactgt
    47581 caataaaaca accagcaagt agcattcaac atttgaagtg gccagcttaa aataaagcac
    47641 aagtgctgct ataatagacc agccagcata aatctcactt ctaagaacag ttggcttacg
    47701 gcctgccagg acatctctga ccacacctcc gcctgcccct gtaagaaccg ctgctacaat
    47761 aacagcgctt aagggctggg ctagtcgaac agcatgtaga gccccctgaa cactaaaggc
    47821 tgcaagtccg atagcatcag tcagcaccgc tgctctcacc cagcccttag ccacaagctt
    47881 aggaaatagc atgatcagaa taatagctat aaaagcgcag gcaaattctg gtctttgtcc
    47941 ccacaaggct tcaataggca gcccgatcag ggtatttcta atagccccac caccaaaggc
    48001 tgtgacaaag cctagaataa aaatccccag aacatcaaac tcctcctcca tagcgacaat
    48061 agcgccggac aaggcaaagg ctatcgttcc aataatgctt aaaagctccc acatatcaat
    48121 tgtcataact cacctaatgc ttcctaatcc cctattagtc taccatcttt ttaatcaaaa
    48181 tataagtcaa aataagagca aggtcctcaa aaatcctact gatgacctgt ttttgtttgc
    48241 accaaagatt tagcccctat ataggctagg ctcctagtag caggagttag gagcgatagc
    48301 ttgccaaatt cacagccttg ttattttcca tgagaaaggg ctctgctgat gtcttggttt
    48361 gataggtctt gtatttatgg tagaggtatt ggtagcaatc ctgtttttga tcaaagagga
    48421 tggcttggta gggctcttgg aaggacaatt tctcaacaaa cagatacttg ctcttatact
    48481 ccactagcac tcccacatga ccaataaaaa ggtaatcacc atctagctga tcgtgaatca
    48541 caacagcaag cattttggct gggccattaa agctaacagc tgagaaatgc tcttgcatat
    48601 gcttggcatg cacctgaata tccttggtgg cttccgtttt cactcttgaa aacagctgct
    48661 taaagcgctc tgtctctgcc tgtgtaaaga gctggcttgt ggtaatggcg tcctcgtcca
    48721 taaataaaag cgtatcatca ctgctggtag gcgcaatcgt catgctatcc tttagaagca
    48781 taaaggtgtt gatccggcaa ttagttccaa tgaaattgcc ttgcttttgc gaccacaact
    48841 catcgattgc taccacatca tagtcaggct gcttctgata ggtaaaggcc cctgtcaagc
    48901 ctgttttgcc aactaggcta ttatattctt gtacaccagc cataaaggca ttgacattag
    48961 cttccttcag ctgatgtgat agggcagccc tgacctcctg ctggctcttt gcactgttca
    49021 tgttggatag gaaaagacgt cccttcttag cctgtggctc tttttgctcc tgcttgggct
    49081 gatcagactg gtgagaagcc tggcaagccc caagagttgc cgtagcaagg attagcaaag
    49141 acatcattac ttttttcatc ataacctcct ttttaatgag tcattcaagc tggtactctc
    49201 catcatcacc aaatgagatt atcagcagct ggcagctaat acgaggttgc tacaacccac
    49261 ttgttatctc tttatgtcat gacctcatcg ttaccagtat agcataaaaa agaaaagcac
    49321 cagctcttga agccttgcag cccttgtgcc ggtgcttttc gttaggagat tacactgaaa
    49381 tagtttttgt ggtagctagc tgctgatacc aataagcgct ttttttaggg taacgctttt
    49441 gggtttcaaa atcaacatag aagaggccat aacgcttatc atagccattt gaccaagaaa
    49501 agacgtccat caaggaccag ataaaatagc ccttaacatt agccccagca ccgatagcgt
    49561 ctgcaatcac agccaaatgc tgcttgatgt aatcaattct agcgtcatca tcaatcctgc
    49621 catcaataca ggtatccttg tagccaaggt cattttcagt gatataaatc tttttatagc
    49681 ctggatagtc tgccttgatc cgcatgattt gatcgtaaag cccctgtgga tagatcatcc
    49741 aatcccagtc tgtacgcggc acatcaacat caaacacgcg ttgaccaacc ccctttatct
    49801 gatatttgga gccgcctttt tctcccttgc cattatgaat gatttcggtc tcaccatggc
    49861 taataataag ccagacttct catcacgtac cttagtggct ggcaggccat attcagggtc
    49921 tagcaggata gaggaggcat agggggttag ctcctctgat accagagcct ttagggcttc
    49981 gatttgccaa ggagctggct ctgtgtcttg gtgggctgcc atcatgcgct ttaaagcccc
    50041 gcgttgatca aaggccaagg ccgaaatgat tcccttacga ctgacctttt ctaaataagc
    50101 ttttttgttt cttgttaatg tcatcttata cctcctctac ttgaatacgg tcaaatagct
    50161 catcaaaatg tgccatgtta acatgacctg ttcttgtttc ttgcgcattt aacatgccta
    50221 aaacattggc ttttttcaga agcgtctcat cgtcatctcc ttctgccaaa gcccaagcaa
    50281 tccctgccac agtagcgtca ccagatccaa caggattgac tacctcaatt ttaggaatgg
    50341 taacacggta aaacctgtta tgatgtttgg caaaggcccc ttgggcacca agagaaacaa
    50401 taatccattc tatcccttca aataaaggtt gactcaacag agagattaaa cgttcctcat
    50461 ctaatgtgac aggttggcct atcaaatcct ccaattcttc caaattgggt ttgataacag
    50521 ttggtttatc tttgccagcc agtaccgctt ttaaaggagc accagagcaa tctaaaacca
    50581 ctttgctgcc atagactctc gccatagtaa tcaagtcttg ataatagtga gcggccagac
    50641 ccttaggcag actgcctgaa aaggttaaga catcaaactg cttagcaata atactcatgt
    50701 ggttcaaaaa gccttcggcc tcgtccatat caatgtaggg accagcttcc agaatttccg
    50761 tctgcatgcc ttcatgtaaa acagcaatac aatttctcgt ttcccctttg attttgaaga
    50821 attggttaga aatgccctgt tcttgtaact gatgaatgac aaagtcaccc agtttcccac
    50881 caataaatcc tgttgccaca actgactgac cagcttctgc taacactctg gtcacattca
    50941 gccccttacc accggctgtt tttgtcgttc tgtcaacacg attaaccgtg tccaaagtca
    51001 gacgatttag aggataggaa atatcaatgg atgggtttaa ggttaccgtt aaaatcatcg
    51061 cttctcccta atcgtggtag tcaccgcgat cccatttgtc caaaaactct gtaaagaagt
    51121 caggatcttc ttggttagca ttatgacttt ccaaatgggc tatcttagca attaacttct
    51181 tattctcttc ggtttcctta tagtctgcct ttataaaggc ctcaataata tcacacatca
    51241 aaagctcacc tgtgatttta ccaccaaagc caatcacatt ggcattcaat tcttctttgg
    51301 cataaagcgc tgttgtcata tccctaacaa gcgctgagcg aatgccagga accttgttga
    51361 cagcattagt gatcccaaca ccagtgccac agatacagac accaagatca gctaggccat
    51421 tggcgacagc ctcaccaacc cttttcccaa aaatcgggta atgggtgcgg gtatggtcat
    51481 aggtcccaca gtcaatcact tcatagccct ttgatttcaa aaaatctgaa acagccattt
    51541 tttcatcagt cacaatatga tcacagccaa tagcaatttt catgatatcc tcccttcgtt
    51601 aagccatttt attgagcatg tcaacacgaa tttgatgacg gccaccatca tagtgaccag
    51661 tcacaaaacc tttagcaata ttcttagcca attcttgacc cacaatttct gctcccatgg
    51721 taatcatgcg ggcattgtta tgaccgcgag tcatgtaggc agagcgttca tctgacactt
    51781 ccgcagcgac catacctttg attttggtag cgaccataaa tggccctgct ccataagcat
    51841 caatcataat gcctagactt tcctcatcag ccttgagcgc cctagcaact gctagagtat
    51901 tgtcaacaaa gtcatcagca atcgccgtca catctgtcac atcaaagcct tcctgctgca
    51961 aaaagccttt aatagcctct tttagatcat ttccatgtgc atctgcacct aagataatag
    52021 tcataggatc tccttttatt gtcattaccg ttcaaaattg tttatttttg ttttgttttt
    52081 tattattttg ttgtttattg aaaaaagaga ctgtttatgc tattatgagt taacaataca
    52141 ccagagaaag tagcggccta tgcttaagcg tgaaagattg ttaacaatta tggaaaaggt
    52201 aaacgccaac ggctttatca ctgtcactga tattatggaa agcctaaggg tttcagatat
    52261 gacagccagg cgaaatttag atgagctagc aagggctgga aaattagtac gtattcgtgg
    52321 cggtgcccag agcatttcta tgcctcaaaa gctggagcgt tcaaacactg aaaagctaac
    52381 cgtacaaatt gaagctaaaa aagagattgc cagatacgct agtcagctca ttaatgatgg
    52441 tgagaccatt tttataggcc ctgggacaac actagaatgc ttggctgagg ctctaatcaa
    52501 ccgtcacatc cgtattatta ccaacagtct gcctgttttt acgattctta ataaaagtaa
    52561 aactgttgat ctcattctta tcggtggtga gtaccgagcc atcacaggag cctttgttgg
    52621 cagccttgca agccagacca tcttatcctt gaagtttgcc aaggccttca tcagctgcaa
    52681 cggtatttat aaaaatgaca ttgccaccta cagtgaaaac gaaggggtta ttcagcgcct
    52741 agcctgtgac aatgccatcg aaaaatacct gctcgctgac aaccaaaagt ttaacgccta
    52801 tgacttttac agcttttatc accttgacaa tatcgacgcc attatcactg actccaagat
    52861 tagtgacagc gttaaggagc gttaccgcca atttgccaag ctcttaatcg caaggccagc
    52921 tgacaatcag gtcagcagct agacagcctg cctctctatc tgtttccacc ctgagtccag
    52981 caggtaaaca aagctatcaa acgaaatagc atcataaaag cgcatgaagc cactaatatt
    53041 gcaatggggc ttcatgcctt ttttaaccta tcacacgtta agcaaagcaa aaagaggcta
    53101 ggacaaaaat ccttcctctt ttaaaatcgt caaactatag agttgattgg agggctctta
    53161 gccctcattt ttcaagcgat gtggcctttt taatcagctg ctcgagggtg gataacctaa
    53221 tcaacatcgc caggtcatga cgattgaatg gttattccac tctttttcta cgctgagggc
    53281 tgtgaaaggg ctcatacgac agcttagccg ctttctaaca gctatttacc tacctcacct
    53341 cttaacgagc agacagccta aatggtatag tccagctgat caagactctt tttatggtca
    53401 aggtcaatat caagaaaggt catctgcttg atattgataa ggctggctac aattgatacc
    53461 ggaaaagcaa ccaccgcttg attgaagaga ctaatattac tattgacaat gcgttttgct
    53521 gctgccaagg ctgcattttc cttagcaatc tcattttgca ggctcaaaaa ctgctcagag
    53581 gagcgcattt ccggataagc ctctcctaca gcaaaaacct cattcaaggc ctgctcctgt
    53641 gtcctcatca catcatttgt ttcctccaag gaaagcccct gacgcagctt cacgagttca
    53701 gtaaagacct tttcctcatg cttggcatag gacttagcga tttttagcat ttccgaaatg
    53761 gtatcatatc tcttctcaag agcaatatcg acatttcgtt tagactcctc tataacgatt
    53821 cgataccttt ctaatttgtt tctcactcca ataagccata gtatagtcat gcaaagaata
    53881 agtgttaaca tagatgacgt cactgacata aaaaagcctc cttaaagctg atgatttagt
    53941 gtatccaaca agcggtacat cttaacaagc ttgtcttgaa tgttttcata ttcgctactt
    54001 aacgatagct tttcaatagc ccctctagag ctaggggttt tcaagagctg ttgaccggaa
    54061 tagaaggaca caacaacagt atcaccattc atataaactg ctacaggcat ctcctctctc
    54121 cattcatcaa gcactgccag catataagga tttaagagca ttctagcgct taattcatct
    54181 gtgcagtaca cattgtacgt ttcattaaag cgaatgtcct ccatttccag ctgcacctca
    54241 ccctttagct tagccttgta gccactatgg accttttctc tgcccaaaaa gcccttttga
    54301 gtcggcacaa ttctaatata acccttgata gctgtatgat atttagccag cagcacctgt
    54361 ccgttaaaat cagtgacccg atgccagtta tcatcctcat tttcctcatg gtaggcataa
    54421 agattgcaaa attctgtctg catgtcatct ccaaaaataa tatggcaatt actgtcatac
    54481 catctggagg acggtgttgc aagctttagt aaggagagct caatccctga atagtaatct
    54541 atcttgacat ctggcagggc ctcttgtaaa acaggcagca aaaagtgatc cacataggag
    54601 agctcatttg ctgttttgaa tgttttcagc cgcggccaaa ccaagccccc cacaaagata
    54661 atgagaaata aggcaagaga tcggtcaacc atgccataca agatgattgc gcctatcacc
    54721 attgccagcc agcccagatt attctttcta gcatttccac tcatctcgct tttaatttgc
    54781 tccagctttt ggtgatgctc aggcgaagct tctatagctc tactcttctc caaaacaata
    54841 ggatctgtca atcgcttagt attttcgttc atctcactta ctccagatac ttctccatca
    54901 gcagcgctca gctgctcttg ataacaccag tcactttatg cttttgctta acctataaat
    54961 gacaattgcg ttacagctaa tttataatat tataccattt ttaaactatt ttttctatta
    55021 ttatatttaa atgacgctca ataataacca cataatgtta atatagacat catcgtgctc
    55081 ttttttacct aatcatgttg tgagcaatac ccccgtttat cagcggaaac cataaaggcc
    55141 tctatgagat caagactatc agcgccagcc cttcttttgg agtcactatt cagcttgttc
    55201 ttcgcatgct gtctttgcct gaccatgatt cagctgctct ttttgattgc ttgttatgct
    55261 cactttttcc gtctcatgct gagcaagaaa aaacagcaaa cccttgcttg gtttactgct
    55321 cttctgttga tgttagtcaa aaaataagcc gggagctaat gacaccctat taactcataa
    55381 agcctgttat cctttctttg tcatagaaca attcacttag tctattctca accaaaatac
    55441 gaagcctgct taaaccgtct tctcatatta acagctaaaa agtggtgtca atatgaagaa
    55501 acctatgatc ggtaacaata atagcacctt taaatctctc agcgataatg taaggttatc
    55561 ctatacctgt catatttttc ggtgctattt gccatatcag gttgctatag cacttggtgg
    55621 cttctggtag ccttaaccaa taaatgatct gcttttttat tcctgctctt tgttttgttt
    55681 atgccttttg tcggcgcagg cctttagctt tactatactg acggtaaggt cggtgagagc
    55741 ctttaccatt ttttatgcct taatcgcaaa gcatttaaca ccactgatat tgagctaagg
    55801 ctcatcgcaa agccagccag cattgggctt aatagagggc cgccaaagac atgaaggata
    55861 cccatagcaa cggggatcat taggctatta tagctaaacg cccaaaataa attttgctta
    55921 accactctga tggtttgacg actgagctct aggcattcca ccacatcacg cactgctgag
    55981 gtcatcagga taacatctgc cgcctcaatc gcaatatccg tacctgagcc tattgagatt
    56041 ccaatatccg ctagggtcaa ggccggtgcg tcgttgattc catcaccaac catagcaacc
    56101 agctgtccgc tagccttcaa atccgcgata atctgggcct tttgagcagg cagcacctga
    56161 ctaaagacct gatcaattcc cacctcatta gcaatcgctt gagctgtgag ggcattatct
    56221 cctgttagca taaccgtttg aagacctaaa tcctgcaagg cccttatagc tgccttactg
    56281 tcagccttta gcctatcagc aatcagcaat aaagcacata gctgattatc cttggcataa
    56341 tacactacgg tttgcccctt taaggcagct tgctcggcat aggtctgagc agcgcttatc
    56401 gcaatcccct gctgtgacat cagctcacta ttgccaacag ctaagcgatg ctggtcaatc
    56461 acaccagtga cacccaagcc cacaagcgat tgaaaatcag tcacagccag caagtcatag
    56521 cccttttcct gtgctactct aacaagcgct tctccaagag ggtgctgcga atactgctct
    56581 aaggaagcca cctcctgaag tccctgcttc tcactagcag caagggggat gatccgctgt
    56641 agctgagcct gaccctctgt cagcgttcct gttttatcaa aaacaattgt ccgcacctga
    56701 taagccttct ctaaaatatc tcctccctta aaaaggatcc cctgctcagc tgcacgacct
    56761 gagccaacca taatcgcggt gggagttgct agacccagag cacagggaca agcaataatc
    56821 aaaacagcta tagctattgt cagggcaaaa tcaaagctct ctctcataac aaagagccaa
    56881 aaaagaaagc tcagcaggga taaacttaat acgataggga caaagactcc tgatacccta
    56941 tcagcaagtg cagcaatcgg agccttggct tgctgtgctt gctccaccag ctcaataatc
    57001 tgtgaaagca aggtgtcatt gccaagccta gagggcttta cccttagcgc tccttggcca
    57061 ttgattgtgc cagcaaacac actatcacct gtcaccttat caactggtag gctttctcct
    57121 gttagcatgg actcatcaac cgtagactgc ccctctacta tcagcccatc aacagccacc
    57181 cgttcacccg gttgaataaa gcaaatatcc tcattagtca cctgctctaa gggaataagc
    57241 tgaagtgctc cctcacgaat aaccctgaca tcagttaccc ttaaggacat tagcttctga
    57301 atagcctgcg aggcccgtcc cttggtacgc ccctccaaat agctgccaag ggtaatcaag
    57361 gtcagaataa ccacaacaga ttcaaaataa agctggtgag caaattgagc agctccagct
    57421 acaatcttaa aacagctata tgagctgtaa ataaaagcaa agctagtggc taaggtcaca
    57481 agcgaatcca tattaggccg cttctttatc aatgccttaa agccattttc atagtactgc
    57541 cgattcaaga aaagaacagg cagggtcagc aaaagctgaa caagaccata gcttatagca
    57601 tgcgactgag gtgctagagc gaccggcagc accaatccaa gcataggtcc cattgcaagg
    57661 tatagcagcg gcagactaaa gagagcagac cacagaaagc gataccattc attgctagcc
    57721 tgctcctcta ggcgctctag ttgccctctc atattggtct catcaagcag ctctgctctg
    57781 tagcctgcct ttcttactgc ttgaatgagc tctgctgagc tgaggctgtc agttgagtag
    57841 ctcactgata gcttctcagt cgtcacatca acagctgccc cctcaacacc tggcagttgc
    57901 ttaacagcct gttcaatcgc tagagcacag gaggtgcagt gcattccctc taatagatag
    57961 gtctctttaa caatcatatc ctctcctttt tctgacaatg acattgtcct ggcacacaat
    58021 cacaccttac atgggatact gctccgactt ttttagcctc taagagcaac tgaaaagcct
    58081 gaatatcttc cagggtcatt ggggtatcct ttagtaatgc cagcaacaag cggctatggt
    58141 ggcgttgaca catgccatca agcctctctc gtagcatagc aagctgtcgc ctgtcctgat
    58201 caagcaagga ctggtaaata taggaccgtc cctgtctatc agcccttagg gcttttttct
    58261 taaccaagcg tccaatcaag gtcttaacgg tagaatcaga ccaatggtgc ttttcatgaa
    58321 gaatagcaat aatctcagag ctcttcatgc tcccattagc ccaaacaaca cgcataacct
    58381 cccattctgc atcagatatc gtatccatat tgctacctct ctttcatcta cggttttatt
    58441 aagtatagct tatttgttta cgtttgtaaa caaataataa ctaaaaaagg tctctttatg
    58501 agaaacagcg tcaaaaaagg actgacagct aaagtcagca gctagctttt aatagtctga
    58561 actttccagt cttatctgat taactttata ttgacaaaat gagtccttgt atattactat
    58621 atgacagtaa tactgtaatg attaaggaga aaacattgac gtatcttaaa agacagctaa
    58681 ttctactagc ccttctactc acagctatag gtagccaaac aatcgttcag gccagcacgc
    58741 gatcctggaa aagctggttt attgagcaat atttttggct taaacgagac aaaagctatt
    58801 atgccgagca ggatgagaat accttctaca actacgtcaa gtcagctggt gaaaagagca
    58861 atcaaggctt taatctcact caaaatgagg tcaacggaac attaaagaca gagtatagag
    58921 acaacatgca ggttcacagc tggaatgaaa actctactaa tccatcaaat caaaaggtca
    58981 ttctctatct gcatggtggc tcctacctaa acaacccgac ctcataccat attgacatgc
    59041 tcaaaacctt gtcaactagc cttgatgcta agattgtatt gccgatttac ccaaaggctc
    59101 cgacctatac ctatgatgtc gctatgccaa gattagttag tctttatcag gatattctaa
    59161 aaagcactaa taacaatgct aacaatatca ccatcatggg agactcagcc ggaggcggtc
    59221 tggcactagg tttggcacta gcattgaaaa atgaagatat taagcagcct aaggacatta
    59281 tcctgctctc accttggctt gatgtcaccc tatcaaatcc agagatccca aattacgaag
    59341 cctctgatcc tatcttatcg gcttggggac tgcgcatagt aggtgatatc tgggcacgac
    59401 gcggggaaaa taacactaag cacccttatg ttagccctat ctatggagat acaagcaacc
    59461 tagcacctat caccatgttt gtaggaactc atgaaatctt ctacccagac attacaaaat
    59521 ttgatggtat gttaaaacaa aaaggacata agcaccagct atttgtcggg gaaaagatga
    59581 accatgttta tcctatttac ccgattgaag aggccaagac agcacaatac caaatcattg
    59641 ataccataaa aaaagagtac gaaccccaaa aataataata caaaaatgcc taccagactt
    59701 gagttttttg ccaaagcctg gtaggcattt tctgatcaca gcatgactac tgtttctttt
    59761 ctagctcacg gagcaattga tcaattttat taccataggc gatagaattg tccttttcaa
    59821 aaaccaaatc cggaatttta tacatggtta attgcttacc aagctcacgc ttaatggttc
    59881 ctgttgcttt ttttaagcct atttcagcct tttgattgtc tgaagctagg tcactcataa
    59941 tggtatagta aaccttagca actgacaaat cgcccagcat ttgcacttct gtgatcgtaa
    60001 caccctgcac acgtggatca cgaacctttt tgtgtaaaat ctcgttgacc tcacgcttga
    60061 tttccatacc aacacgatca atacgatgat ttgtcatggc ccttcctttc tattgtcaaa
    60121 tagtacaggc tctcagtagc tcaataacaa gagaaaagct tgatgacttt caagcctttt
    60181 tctctattag gctgatggct atactattaa tagtgactgt tcaaatcaag tggtgacatt
    60241 gtctattgtc ttgagacgag gctatttaag ctactagcca ccacgattat ttacgggtaa
    60301 tttcttccat gacgtaagcc tcaatggtat catcgacctt aatgtcatta aagccttcaa
    60361 tcatcaaacc accctcttgg gcattcccaa tctccttaac atcgtcctta taatgcttaa
    60421 gactggctag cttaccatca aagataacca cgctatcacg aatgacacgt acacttgaat
    60481 cacgcgttac cttaccatta acaaccataa agcctccgat tgtcccaacc ttagagacct
    60541 taaaggtttc acgaataata gcctcaccaa gcattttttc ttgatactca gggtcaagct
    60601 tacctttcat ggcttcctca acctcttcga tcaccttata aataatgcta tgcaagcgaa
    60661 tctcaacatc gtctgtatca gcctgctgac gcgcctgtgg tgttggacgc acattgaagc
    60721 ctatgataac agcgtttgaa gcctctgcca aggtcacatc tgactcattg atcgcaccga
    60781 cagcagagtg aacaacattt actcgaacgc cctcaacatc aattttaagg agtgaggctg
    60841 ccaaagcttc cacagagccc tgcacgtctg ccttgatgat cacgttaacg gttttgattt
    60901 cccctgcctt gagggtatca aataggttat caaggctgac acgctgcgtg ttttgacgtt
    60961 gcttgagaag ggcacgctta gcacgctcct cccctgctgc acgcgctgct ttttcatcag
    61021 catagaccgc aaaatgatca cccgccatag gggtttcatt gagaccagta atagataccg
    61081 gtgtggacgg ctcagctgat ttcacacgac gaccaaggtc atttgtcatg gcacgcacac
    61141 gaccaaaggt gttaccaaca acgattgggt cttgtacgtg tagggttcct tgttggacca
    61201 gaagtgtcgc aaccgcaccc ttacctttgt caagtctagc ctcaatgacc gtaccaatcg
    61261 cacgaaccgt aggatcagcc tttagctctt caacctcagc taccaaaagc actgtttcta
    61321 gcagctcatc aatgtttttg ttaaatttgg cagagatttc aacaaactca cactcaccac
    61381 cccaagcagt tgagatgatc ccatgctcag ccaattctga aataacacgc tcaggattag
    61441 cccctggctt gtcaatcttg ttgatggcaa cgataattgg aacaccagcc gccttagaat
    61501 ggttaatagc ttcaatggtt tgtggcatta ccccgtcatc agcagctaca atcaaaatgg
    61561 taatatctgt cactgacgct ccacgtgcac gcatgcttgt gaaggcagca tgtcctggtg
    61621 tatccaagaa ggtaatcttc ttgcctgcct cctcaatctg gtaagctcca atatgctggg
    61681 tgatccctcc tgcttctcct gttgcaacac gagaatttct aagggtatca agcagggtcg
    61741 tcttaccatg atcgacgtgt cccataatgg taacaaccgg tgcacgctca acaatattct
    61801 caggattaag gtagctatca tcagtaaaga agcgctcgat atcagcttca tcaacctcca
    61861 ccttggcctt agcttcaatg ccataatcca ccattaagag ctcaatggta tcaccatcta
    61921 aggattggtt ttgcgttgcc atcacaccca tcataaataa tttcttgaca atctcagccg
    61981 gctcacgctt gatccgtttt gcaatttcag caacggtcat tccttctgaa tattcaaatt
    62041 cttttggtaa ttcatggaat ttacgctctg ttactggttt tggagctgtg ttgctattct
    62101 tatgatgctt accttttttg tttttcttgt tgttattcca gttactattc ttttgatttc
    62161 tcacttggtt ttgactattc caactcttct tatttttctt ttgtccatct tctaggccat
    62221 gatcccgatc atgccctttg tctggacgat tttgtttttt acgacgctta tcaaccggtt
    62281 ttgctaccga tgcagcagcc atactagcaa ccgactcagt agccttagct gaggcttcac
    62341 gatgcttttt gtcctctgtc tgagccttga gggcggctgc cttagcctct tgccttgcct
    62401 gttgctctaa gcgtttagcc tcctcttgct cacgaaagcg tgattccctt tgtctggcat
    62461 actctgcgtt ttgctcagcc tttaaggcag cagcacgcgc cttaaaatca atcttaggag
    62521 caccggcttg ggtctgccct tgacgtcctg tatcctgttg acgactatta gcgttaaagg
    62581 aacggttttt gtcacgatta ccagcttgtc tatgcccatc gtttcggtta tttccagatg
    62641 atggcctgtt atcaaagcgt ctatctcttt gctgattttg tgacttgtgg ccagctcgct
    62701 ccgtctgctg accttgtgat cgtccaagtt gacgatagtc tgacttgcgg tcattagagc
    62761 gattttgccc agcctgccgt ctcgctacct gctccttggc acgtgcttca cgctctgcct
    62821 tgaaattgcg gctctttggc ttaacagcaa ccggctgtga tgcttcttgt gtcgcagcag
    62881 ctggcttttc tgctgcttta gaggctgctg gctgtggtgt agtggcctta gctgcttttg
    62941 ctttttgttc tgctacttgc ttgtcttttg ctgaacctgc ttgaacattc ttagtcacac
    63001 ctgctgaaaa gctagaggca attttgttag catctgcttc ttcgacgctt gacgcatggc
    63061 ttttgacatc taatcctaag gatttagcac gctcaacgac ttctttacta cttttgccaa
    63121 tttccttggc aatttcatgt aatcttttct ttgacaattt gtgtcctcct attcgtctat
    63181 ttcataagag tcctcatttt ctttgaaaat ccagcgtctg caatggcaac caccttacga
    63241 ggcttgccaa gtgcagcact taattccagt gcactaaaca ctgtggagac ttctacattg
    63301 taataattac ttttatctgt tactttttta gtgatatttg ggccagcatc attggctaaa
    63361 aaaacaagat tgacttcctg atgtcgaatg gctttaatga ccaattcctc acctgaaatc
    63421 acttttttgg cccgctgagc cagtccgatc aaatgagata atctatttaa actattcaag
    63481 gcctagctct cttcttttaa ctttgtgatc aacatgtgca atcacttcat cgtaaaagct
    63541 ctctggcacc tccattgaga agctacgatt aaacacctgt tttttctttg ccataagtgc
    63601 ttcttggtta tctagcttga tataagcacc acgcccattt tgcttgccgg ttggatcaat
    63661 aaaaatctgc ccctccttat ttttgacaat acgaaggagg tcacgcttat caatgatctc
    63721 accagaaaca agcgacttac gtaaaggtat tttttttact ttaggcataa aacacctctt
    63781 ttcttacact tcctcgttgg ttaagagctc ctctgtagct actgcttcag tcattgctgc
    63841 ttctttttct gcttcaaggc gttcatattc actggctgat ttgatgtcaa tgcgatagcc
    63901 tgtcaaatga gctgccaaac gaacgttttg accacgacga ccaatagcaa gcgatagctt
    63961 attatcaggc accaccacag tcgcacgctt aagatcgtca tcatcaaaga gaaccatatc
    64021 aacctcagca ggtgcaatgg cattgtagat aaattcagca gggtcatcta cccattggat
    64081 aacgtcaata ttttcttcta ctgggatctc aagtcctgtc ttagcatcat agcgctttgg
    64141 atggaattta ctgataacct ttttgatgtt gctgccgcca cgaccaacaa tcgttccaat
    64201 cgcatcaaca ttgggattgt ggctacgcac agcaacctta gtacggtcac cagcctcacg
    64261 agaaacactc ataatctcaa cggtcccatc aaaaacctct ggaatttcct gttccataat
    64321 gcgcttgatg aactcagggt gactacgact aacaaagacg ttaaccccct ttggattgtt
    64381 ttccaccttg tagacataga catcaatccg atcatgtgat ttgaaggttt ctcctgggat
    64441 ttgatcctga tgtgagagct gagcctctaa ggaaccaagg ttaacataaa tgaaacgttg
    64501 gtcaaaacgc tcaaccgtac ccgtcatgat ttcaccttca tgctgcttgt actcattgaa
    64561 ggtgatttct cgcatctgac gacgcatcct ttccataatg gtttgctttg cagactgagc
    64621 agccacacgt ccaaactcgc tgactgattc ttcaaaacga atcttatctc ctaactcata
    64681 ggctgagcta atggcaaggg catcgttcag gctaatttcc agacggctat caaatacctc
    64741 ttcaacaacc tcacgaaccg taaaaacctg aaaatctgct gttttatcat taaattcaat
    64801 gacgcaggat tctgcttgac cataacgacg tttataagct gatttcagtg attcagtgac
    64861 tgcctcaatg atatctgcct tatcaatgtg tttttcttct tccaaaatac ggaaggcttc
    64921 tagcatttct ttgctcataa tgttgtctac cttgctctca aagcttggta aaaatccttt
    64981 cttatcttat aaattaatcc atttagggct tagccaaccg actaaagcaa atcgctcagc
    65041 aattgcctta taatttgaca gctaaacgag ccttagccac tgcttggtaa ggaatctcaa
    65101 ctgttttgtg acgcgtctta tctagataat caatggttag ggtatcacca tcaaaagcca
    65161 ctaaatctcc ttgaaaaacc ttcaccttat caattgcccg atagaggctg acattaatat
    65221 atgagcctac agcagccttc aagctctcag cagtctttaa tggacgctct agcccaggac
    65281 tggaaacctc cagcatatac tgatctggga aagggtctgg agaaatcgta tctaagagtg
    65341 gactgattaa ctctgtaagc tcagcagtat cctcaacggt aatcccagaa gccttatcaa
    65401 ctaagatact aaggacataa tcattgccca ttttgtcgta ttcgatgtcg accaattcat
    65461 agggtgcttt aattacaggt tctacgattt gggtaacaat atcaataata gctgtgtttg
    65521 cgatgttaat aacctccttt actgatgact gctatacctc tatagccttg tcctcttgat
    65581 aatcaacaca aaagtggcga gatatttctc accacccttc tgtattgctt taacctatta
    65641 taccacaatc aaaatgaatt gcaagaaaat ccctactaaa agtgtcaata agacctcaaa
    65701 aatcctattt tttaaaagga gaggagatct ttaaccttgc ttttttctct ttccttatcc
    65761 cctctaacct ctgtattcat atgataaaat aaaatattaa agggtaaaaa agacaactaa
    65821 aatattattt gcggctgctt catggtcttt accaaaacga aaaaacctcc catcagaaca
    65881 gatctatgca tatgcgagag aggccattgg taactcaata acatcattaa taaagcttaa
    65941 attagttcaa tttgtaattt taa
//
LOCUS       DARYMD010000004        58406 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYMD010000004 DARYMD010000000
VERSION     DARYMD010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58406
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..600)
                     /locus_tag="TU818_000202"
     CDS             complement(<1..600)
                     /locus_tag="TU818_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0923066.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLIGTGLLGNKVVYGDMSADVK
                     KIEQVLQSDSGKLKTVLGQISDPNTLFALFAIISADVNIDPESFSFILNGPITPLLSY
                     FNNPNKNDNRKAVVNEIKKRVSALEQAQKLETKAKIEKQIAESELEKTRNAFKVTIEN
                     LHKLEGLLDTEKQKTRKVEEDYQQAKTDKEKAEADKRNAE"
     gene            1005..1649
                     /locus_tag="TU818_000203"
     CDS             1005..1649
                     /locus_tag="TU818_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923067.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEVVFAALQNDNRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            1654..2403
                     /locus_tag="TU818_000204"
     CDS             1654..2403
                     /locus_tag="TU818_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL0923068.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TU818_000205"
     CDS             complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TU818_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL0923069.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TU818_000206"
     CDS             complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TU818_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL0923070.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGHKIAKANAAE"
     gene            3125..3955
                     /locus_tag="TU818_000207"
     CDS             3125..3955
                     /locus_tag="TU818_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923071.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPIIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSNRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            4015..5295
                     /locus_tag="TU818_000208"
     CDS             4015..5295
                     /locus_tag="TU818_000208"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL0923072.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEVLAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGAYANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKT
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(5500..6792)
                     /locus_tag="TU818_000209"
     CDS             complement(5500..6792)
                     /locus_tag="TU818_000209"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0923073.1"
                     /translation="MAINAIFHLYTSVVNIVIVNYFFRQKNGQLATFKNIGYLSFLVF
                     IECCTHFFVSGSYASLITLTCSLVTSLIISSSYRYSMKQCIFWSVTLQSIGILLEASL
                     GIILISLKYQISSISGTFLFINLLTISSIIIIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISDQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(6782..7498)
                     /locus_tag="TU818_000210"
     CDS             complement(6782..7498)
                     /locus_tag="TU818_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0923074.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSCHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            7752..7976
                     /locus_tag="TU818_000211"
     CDS             7752..7976
                     /locus_tag="TU818_000211"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923075.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDSNYETGAS
                     FTHKLWPHFKECPACGHGNSNDWEIFSHYG"
     gene            7987..8907
                     /locus_tag="TU818_000212"
     CDS             7987..8907
                     /locus_tag="TU818_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923076.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGKIRGLSGKLLETEVQELIQELGLIKWQNTVGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVKTLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            8894..9634
                     /locus_tag="TU818_000213"
     CDS             8894..9634
                     /locus_tag="TU818_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923077.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMMLVTQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVVKLVVLLLWLVATALLSVNWLNRQS"
     gene            9791..11539
                     /gene="aspS"
                     /locus_tag="TU818_000214"
     CDS             9791..11539
                     /gene="aspS"
                     /locus_tag="TU818_000214"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL0923078.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVKSKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            11532..12479
                     /locus_tag="TU818_000215"
     CDS             11532..12479
                     /locus_tag="TU818_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0923079.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVTNIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            12495..13376
                     /locus_tag="TU818_000216"
     CDS             12495..13376
                     /locus_tag="TU818_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0923080.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVIVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            13520..14434
                     /locus_tag="TU818_000217"
     CDS             13520..14434
                     /locus_tag="TU818_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0923081.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            14606..16000
                     /locus_tag="TU818_000218"
     CDS             14606..16000
                     /locus_tag="TU818_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL0923082.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKVQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMENRLTRMKEVNSPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSRIAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLEPDQTAVELISRQSSQDRVTILNYLAMMGIDYDKANQKVAVLSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKDHHLTAYHFED"
     gene            complement(16048..17739)
                     /locus_tag="TU818_000219"
     CDS             complement(16048..17739)
                     /locus_tag="TU818_000219"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL0923083.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAETDPSLDEEAREWFRRLE
                     ERDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEVLELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDDPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            18016..18453
                     /gene="argR"
                     /locus_tag="TU818_000220"
     CDS             18016..18453
                     /gene="argR"
                     /locus_tag="TU818_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL0923084.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            18455..18805
                     /locus_tag="TU818_000221"
     CDS             18455..18805
                     /locus_tag="TU818_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL0923085.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQHLLQRTDYNQKAYQMK
                     RHQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGT
                     IEDELNKEFNDGKG"
     gene            18792..21347
                     /gene="mutS"
                     /locus_tag="TU818_000222"
     CDS             18792..21347
                     /gene="mutS"
                     /locus_tag="TU818_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL0923086.1"
                     /translation="MAKANVSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQLNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRAWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIETKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESKIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAADDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADTVLTKLEAQSQARESVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            21494..23476
                     /gene="mutL"
                     /locus_tag="TU818_000223"
     CDS             21494..23476
                     /gene="mutL"
                     /locus_tag="TU818_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL0923087.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELAHVVDVVNRLSLAHPEIAFTLISDGKQLTQTSGAGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDPQKNDFFTKETVVSEDSPQGFNHETLV
                     DSGVKQVDNLQLAKTESEAAAPSVKYASRPDPMLSDGEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            23487..24710
                     /locus_tag="TU818_000224"
     CDS             23487..24710
                     /locus_tag="TU818_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0923088.1"
                     /translation="MREFFQLPKQIQIRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVASTLGWLLTILANVPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTVINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACV
                     GLYVIVLSAKMKKKV"
     gene            24712..25308
                     /gene="ruvA"
                     /locus_tag="TU818_000225"
     CDS             24712..25308
                     /gene="ruvA"
                     /locus_tag="TU818_000225"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL0923089.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDITYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            25318..25869
                     /locus_tag="TU818_000226"
     CDS             25318..25869
                     /locus_tag="TU818_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL0923090.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDISAVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(26305..27150)
                     /locus_tag="TU818_000227"
     CDS             complement(26305..27150)
                     /locus_tag="TU818_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0923091.1"
                     /translation="MRWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPK
                     FDTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILNQFYNQVSAVNITELEKLRQKCFN
                     YLKNKNDIPISYILDSVEVMISLRKKGVKNNQDLQELAYKIWNSLVKQDTWYEKDLQL
                     LHTILFHFPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECE
                     EITLLTIKLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHE
                     LKNYR"
     gene            27447..28019
                     /locus_tag="TU818_000228"
     CDS             27447..28019
                     /locus_tag="TU818_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL0923092.1"
                     /translation="MKKRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTSRKYFK
                     AGWQLYGNYCGPGHNGNHFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            28013..28303
                     /locus_tag="TU818_000229"
     CDS             28013..28303
                     /locus_tag="TU818_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923093.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
     gene            28989..30260
                     /locus_tag="TU818_000230"
     CDS             28989..30260
                     /locus_tag="TU818_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL0923094.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVV
                     SSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIAALYAFNMVRKTLLKSENLL"
     gene            30354..31490
                     /gene="recA"
                     /locus_tag="TU818_000231"
     CDS             30354..31490
                     /gene="recA"
                     /locus_tag="TU818_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL0923095.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            31866..32264
                     /gene="spx"
                     /locus_tag="TU818_000232"
     CDS             31866..32264
                     /gene="spx"
                     /locus_tag="TU818_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL0923096.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
     gene            32377..32646
                     /locus_tag="TU818_000233"
     CDS             32377..32646
                     /locus_tag="TU818_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL0923097.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            32643..33062
                     /gene="ruvX"
                     /locus_tag="TU818_000234"
     CDS             32643..33062
                     /gene="ruvX"
                     /locus_tag="TU818_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL0923098.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            33072..33371
                     /locus_tag="TU818_000235"
     CDS             33072..33371
                     /locus_tag="TU818_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL0923099.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            33919..35478
                     /locus_tag="TU818_000236"
     CDS             33919..35478
                     /locus_tag="TU818_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL0923100.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSVQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLIHYVTGIQKVALGFTAIYYLLSISLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPRTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVFSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRMVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLTEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAVYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            35575..37773
                     /gene="nrdD"
                     /locus_tag="TU818_000237"
     CDS             35575..37773
                     /gene="nrdD"
                     /locus_tag="TU818_000237"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL0923101.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKL
                     LPAHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDVTSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKAYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            37879..38025
                     /locus_tag="TU818_000238"
     CDS             37879..38025
                     /locus_tag="TU818_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923102.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            38053..38988
                     /locus_tag="TU818_000239"
     CDS             38053..38988
                     /locus_tag="TU818_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL0923103.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMADFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLVDRRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            39001..39495
                     /locus_tag="TU818_000240"
     CDS             39001..39495
                     /locus_tag="TU818_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0923104.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEQLLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREVLVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            39505..40119
                     /gene="nrdG"
                     /locus_tag="TU818_000241"
     CDS             39505..40119
                     /gene="nrdG"
                     /locus_tag="TU818_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL0923105.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(40577..41308)
                     /gene="yaaA"
                     /locus_tag="TU818_000242"
     CDS             complement(40577..41308)
                     /gene="yaaA"
                     /locus_tag="TU818_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL0923106.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSIRIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHLKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSN
                     EFRDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETNYYYIKKES"
     gene            41756..41959
                     /locus_tag="TU818_000243"
     CDS             41756..41959
                     /locus_tag="TU818_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0923107.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            41961..42414
                     /locus_tag="TU818_000244"
                     /pseudo
     CDS             41961..42414
                     /locus_tag="TU818_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            42424..43098
                     /locus_tag="TU818_000245"
     CDS             42424..43098
                     /locus_tag="TU818_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL0923108.1"
                     /translation="METKHSAVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            43128..43565
                     /locus_tag="TU818_000246"
     CDS             43128..43565
                     /locus_tag="TU818_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923109.1"
                     /translation="MKNDRWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKAQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYVMIRAWVSKHM"
     gene            complement(43788..44561)
                     /locus_tag="TU818_000247"
     CDS             complement(43788..44561)
                     /locus_tag="TU818_000247"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL0923110.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSLARSKEIAGQLH
                     LSYAQSHQELIDQVDFIILGIKPQLFETVLSPLQFKQPIMSMAAGISLDRLAQLTSSH
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDTFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(44645..45712)
                     /gene="pepA"
                     /locus_tag="TU818_000248"
     CDS             complement(44645..45712)
                     /gene="pepA"
                     /locus_tag="TU818_000248"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL0923111.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTVRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAASLPAVSDIVFDGGFTDKTEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNPAHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKKLDRSTVDLIKKY"
     gene            46057..46404
                     /locus_tag="TU818_000249"
     CDS             46057..46404
                     /locus_tag="TU818_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL0923112.1"
                     /translation="MAEIVSFCSSLLFPFCDKMKGMNGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQRVLVELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYH
                     YHKGSIDFKEDLT"
     gene            46401..46718
                     /locus_tag="TU818_000250"
     CDS             46401..46718
                     /locus_tag="TU818_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL0923113.1"
                     /translation="MIIPTSKEELARLIETEPRLVLFFTADWCPDCQYIYPVMPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            46733..47359
                     /locus_tag="TU818_000251"
     CDS             46733..47359
                     /locus_tag="TU818_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL0923114.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVARVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPAPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDKAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKESFGMMCSPRELALPNAPQKRGIIELGDAAAVGEAFDPAKHWQS"
     gene            complement(47662..48375)
                     /locus_tag="TU818_000252"
     CDS             complement(47662..48375)
                     /locus_tag="TU818_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0923115.1"
                     /translation="MTINLKAYQDMLTRPWGKLMYDLIFAQLGPIAGKTILDFGAGFC
                     ITAEALAVQNEVTAIEPNPDLLFAQKQESIHKIKGSLEALEKLPDQAFDMIICHNVLE
                     YIAPKEHAIYLAQMERLLKPKGQLSLIKHNQVGKVLHSVIFEHDYDKALNVLNGQAFE
                     SLSFAAGQTYSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEVLRTIELAIC
                     DQKPYKDMAFFQHVTLSKA"
     gene            48487..48882
                     /locus_tag="TU818_000253"
     CDS             48487..48882
                     /locus_tag="TU818_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0923116.1"
                     /translation="MYNKVILIGRLVAKPELNKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            49329..50303
                     /locus_tag="TU818_000254"
     CDS             49329..50303
                     /locus_tag="TU818_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0923117.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHQAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFREGKNLTITTKNAQGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNMDSETPAVFTAVTDPVSAGLVDTLAKPGGNMTGSTDATDVENQIDLLTKAL
                     PQARTVGIFYNSSEVNSEIQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLASQVD
                     AVYLPTDNTVASTATTIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            50321..51283
                     /locus_tag="TU818_000255"
     CDS             50321..51283
                     /locus_tag="TU818_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0923118.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAQGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLTKVGYRVIKKGIATSNDVQDTAASLMRAV
                     DALFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            51398..52282
                     /locus_tag="TU818_000256"
     CDS             51398..52282
                     /locus_tag="TU818_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923119.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICAAGIVSGVSPLLATFLAFIGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVIFLLALLMKTQLGLALR
                     STGDNNPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIVIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            52291..53094
                     /locus_tag="TU818_000257"
     CDS             52291..53094
                     /locus_tag="TU818_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0923120.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDIEEGDFISVIGGN
                     GAGKSTLMNTLAGTLAFDQGDILLEGKSIKHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMASLAKPKVLLLDEHTAALDPKTSTMVMALTKQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKREEKAKLTVDHLMALFHQNSGHTLLDDALVLG"
     gene            complement(53193..54197)
                     /locus_tag="TU818_000258"
     CDS             complement(53193..54197)
                     /locus_tag="TU818_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923121.1"
                     /translation="MLSRHNIVQRSLVKHLLLLATLLGSLGLGNSLSKADSQDHLHVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLHPELRLTEQ
                     ETQSNKQQTPSKETRRAEASRNSNTSRPAASLSSYRRYSDAQILANIKAELEKSDYDA
                     IKQFKDDFINRLHSQEIQLNPYRDSSKIPALLFRELQYYLKLHPEMIYHLDGINLSPE
                     VADSFVSRLANAYSLDNMLSILQEARAYGQGIIDTIAKRAEAKAILTEHKNTYKDRNQ
                     RVSEDYYSTAFHEIDEAITIQQLNKAIEIVENEAYRIRNKSFDYNRRHHGFITLRKIS
                     "
     gene            complement(54483..55124)
                     /locus_tag="TU818_000259"
                     /pseudo
     CDS             complement(54483..55124)
                     /locus_tag="TU818_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
     gene            complement(55145..56122)
                     /gene="dusB"
                     /locus_tag="TU818_000260"
     CDS             complement(55145..56122)
                     /gene="dusB"
                     /locus_tag="TU818_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL0923122.1"
                     /translation="MTRLNSPFRIGHVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLARVSRAITRIPFIGNGDVRTVQDAR
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFAKKLDIAKDHLKRLIR
                     LKGEAIAVREFRGLAPHYLRGTAGAAKIRSAVSRAKTLAEVETIFAQIH"
     gene            complement(56109..56981)
                     /gene="hslO"
                     /locus_tag="TU818_000261"
     CDS             complement(56109..56981)
                     /gene="hslO"
                     /locus_tag="TU818_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL0923123.1"
                     /translation="MDKLIKTISASGAFRAYVLDCTETVRYAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPGASVEEISHYEKRIQEMPAISTLLASENHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQ
                     FDQTDLEVLINDKA"
     gene            complement(57231..>58406)
                     /locus_tag="TU818_000262"
     CDS             complement(57231..>58406)
                     /locus_tag="TU818_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEL0923124.1"
                     /translation="LHNLSQLPVLVLSQNLELLQAYDDEERRFPYYELIKTLDIPSNT
                     ELTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLKRYPDKSKKELV
                     GYISTIPHFPASHIRSLLIAVDAFFDTNFEMSCQQSINDLLEEAQLIWEDPHIIANLE
                     LENTPSFHVPAVLNYLNHIIDLVKLGNTELLKHEINCIPSSDVVSSSIPALRAEKNLS
                     IIYFIKLLELSFTENTDVAKNYERIKHFMNLTEKATDLLKVLQIRAAAIISLSESLTN
                     KSVSDKQQIYNSILYYVDKHLYSKLKVSDIAKHLYISESHLRAVFKMYSSISLQTYIL
                     KEKVQEAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDYLAHYQQSITK"
BASE COUNT        16833 a        10320 c        13187 g        18066 t
ORIGIN      
        1 ttccgcattc cttttatcag cctctgcttt ttctttatcg gttttagctt gttggtaatc
       61 ttcctcaact tttcgagttt tttgtttttc agtgtctaat aatccctcta gtttatgtaa
      121 attttcaatt gttactttga aagcattcct agttttttct aattcacttt ctgcaatctg
      181 tttctctatt ttagctttag tttctaattt ttgagcttgc tccaaagctg agactctttt
      241 ttttatttca ttaacaactg cctttctatt atcatttttg tttggattgt tgaaatatga
      301 taataatggt gtgattgggc catttaatat aaaactaaaa ctttctggat ctatatttac
      361 atcggctgat ataatagcaa ataaagcaaa caatgtattg ggatcactaa tttgtcctaa
      421 tactgttttt aacttaccac tatctgattg taaaacttgc tcaatttttt ttacgtccgc
      481 actcatatct ccatacacaa ctttatttcc aagtagtcct gttcctatca ggcttcctgt
      541 gatgagagta gctgctaggg cttgatgaca caagcgtctg atgtttgatt gtcttttcat
      601 gatttagtcc tcacatatcg tcgaatgttt tttctaaaat tcttccaaaa aatcttaaca
      661 tgacgcttgc aggctgtgaa tacgttttgg gcaattcgcc tccgtagttt cgtttttttt
      721 aattcaatca ttaaacgtct gattttatca tgatataatt gatcttgttc aaggctgatc
      781 aggaaattct tgatgaagat gacagcttta tatcggtgtt tgggaaacca taagattggc
      841 aaggctacgc tgggcttagc tgacattgtt gcttcaaaat gctttcaggt gtagaaatgt
      901 tgacaagtat tctttaaaaa gatagactat agctagtagg atagaggtat gcacaggtga
      961 cagatgtgat acttgtgttt tttgctattt ttggaggttt ctgattgcct attgcagctt
     1021 atcaatatga aagtgttgtt gagattatta gtgaaatcaa tcgattacac tattcatttt
     1081 cttcgggttt aggagctctt ctatgcttta atttgaaaaa gagtgtcagt tcggtagtcg
     1141 ttaacaatcg tattgatagg gagttccaag agctcatcgt ttcttataaa gcaaggctaa
     1201 ataggaatat tagtcaagtc tcaagcatac gacatcagtt tataggcatt agatggagaa
     1261 taaagcaagc agaatctatt agtgagaagc ttttatacta catgagcgag aatcatgagt
     1321 ttggaaggat tcccttaaat aaatgtttga atgattttct tggatttagg atcttggtca
     1381 ataacttaga agttgttttt gctgctttgc aaaatgataa tcgagtgact aatattgcta
     1441 aattgtattt aagaacagat ggcgactata aaggtatcca tctatatttt aaaaatggaa
     1501 ataatcggtt ttttccatgg gaattacaga tttgggatcc agagcaatca cgcttaaatg
     1561 agctgtcaca taaagagcat aagcaaaaac gacaatatat atcactaccc caacattatt
     1621 ttgatgctaa tttagaaaag gaggaataac cgcatgtatc agcattttat tttagttgct
     1681 agttcatatg caagaggtga gagagttggc tttcacttag cgacagaagg tcaattggat
     1741 catgttgcca ttgaagaaaa aatgcagcgg ctgagtcata tcaatagaga tgatgttggt
     1801 gtgcattctt ttgttacaga tagtgctgat tggcaaagtg tcattgagtt agattccttt
     1861 tttgaggata ttatggtttg tcaagacttc gatgaatttg aacaggtttt acaatccgac
     1921 tctaaaatta gtgctattga tgttgctaaa tttttcttag caatgcgtcc actctcacac
     1981 ttacaattgc aaaagttagt ttatcttgct tataaaacat atcttcttgc ctatggtgaa
     2041 tccttatttg atgaaaaaat agttgctttt caatatggtc ctgtagtaga agaggtgtat
     2101 cacagcttta aaaaatatgg ttctgaggtg atagatatcg atgatcatac agaatatatt
     2161 ttaaaagaca tacatcttcc gcaagcctta ggtagaatgc tattggtcga agacgcaaag
     2221 aagattgtgc ctgtattatt agatgttgtt aaacagtatg gagatttaac aggaggagaa
     2281 ttggttaagc tgacgcactc tgaaaaggga ccttggcaga cggtttttcg tccacagtta
     2341 aattgtgaga tcactgatga ggttatttta gcccaaggca gatatgaaag attatcatca
     2401 taagtacctt tgcttattgt attagctgag aatactcagt tgtctcatca aaaccaaaac
     2461 aaaaaagcct ttgaaacgtt gatttcaagg gctttctgta tatcgtctta ttttacctct
     2521 gtaaacacaa catgtttacg tagttttggt gagtattttt tcaattgaag gcggtctgga
     2581 gtgttacgtt tgttttttga agtaaggtac aagcgttcac cagattcttt gtgttcaagt
     2641 gtgatattta cgcgcatggt atctcccttc tattattcag ctgcgttagc tttagcgatt
     2701 ttatgtcctt tgtagtatcc cttaagtgag acacgatgtg aacgtgagta atctccagtt
     2761 gtttcgtcaa attttactga tggtgcagtc aatttgtagt gtgtacgacg tttgttcttt
     2821 ttagcttttg acgtgtgacg tgcaggaact gccatttttt ctatcctccg ttaaatgatc
     2881 aagggtctat taaaagattg gtgacaaact ggtgtgcatg atcttatgct aacctatctg
     2941 tctcaaatct ttgacccatt gttatctatt tgatgttatg gctttcgcca actttagtat
     3001 catatcatat cttctatgta aagtaaagtt acttgacaaa aattttatta aaaagctctg
     3061 ctattctcca aaaatcctaa aaaatggtaa aatgagacaa aggtggttat tttaggagat
     3121 taagatgttt ggaaaattat taagtctgtt aggctttgtc gttgctttga ctggttgtgg
     3181 tgtttcacag gcagaaaaag aacgtgttgt aacagagtat agccccatta ttattaaaaa
     3241 atttcaaacc ttaggatacc aagggaaaat cactgtagac gactatacta agatgattga
     3301 gacaggtagt gagagacttt attttaccta cagcgaagaa gtagacggta aggttattag
     3361 tctgaaggat agtatttcga ttgctaccta taaatcacct gaggaagatt tggctgatgc
     3421 agaagttgac atgggaatta gggaagaagc tatgtggcag caaccagctg tcaaagcgca
     3481 agctgctcag atcaaacaac tatttagcga gttggagact gaggatttga agcttatatc
     3541 cgtaacagga caaagtgtcc agacgatttc tgattcagat ggagagctga ttagggaaga
     3601 tgttgtacga ggcaggaatg aattatctca agatgcatct aataatagag aagctgggct
     3661 atcaataggt ggctattatc atattgatgt ttcaaagtat ttgaaaaatc acgtgttgga
     3721 aattcgtata gattttgatt ggcgaatgtc agaagaggaa caagacgatt tgtctggccc
     3781 caggttggat ttttctgata gaataaaaag tctagacttt acctgcttgt gggatggcta
     3841 ctataaagtg gggtttgaca gggtgagtag atctaatcga agtggagata ttcaagatat
     3901 gattgtttta gatattcgag gcggtaaatt ggttcgtagc ttttctgtac tttaacagat
     3961 taatgaagct attctatggt aaaatatata aatactagta aaagaggaaa taaaatgaag
     4021 cttcaaaaac caaaaggaac acaggacatt ttgcctgtgg ctgctgctaa gtggcaatat
     4081 gttgaaggtg ttgcacgtga aacctttaag caataccatt atggtgaaat ccgaacacct
     4141 atgtttgagc attatgaggt cattagccga tcagtaggtg ataccactga tattgtgacc
     4201 aaggaaatgt atgacttcta tgataagggc gaccgtcata tcacacttcg tccagaagga
     4261 acagccccag ttgttcgttc gtatgtggaa aacaagctct ttgcgccaga ggttcaaaag
     4321 cctgtcaagc tgtattatat tgggtcaatg tttcgttatg agcgtccgca ggccggccgt
     4381 ttgcgtgaat ttcaccagat tggtgtagag tgctttggct ctgccaatcc tgccactgat
     4441 gttgagacga tcgccatggc ttatcacctc tttgaaaggc ttggtattaa agaggtgacc
     4501 ttgcatttga atagccttgg aaatgcagct agtcgcgcag cctatcgtca ggccttgatt
     4561 gattacctat ctccaatgcg tgagaccttg tccaaggata gtcagcgccg tttagatgaa
     4621 aaccctctgc gcgtgcttga ttccaaggaa aaagaggata agattgcagt agcaaatgcc
     4681 ccatctattc ttgattatct tgacgaggag agtcaggctc actttgatgc tgtgcgcagc
     4741 atgcttgaag tacttgctat tccttatgtt attgatacca atatggtgcg tgggcttgat
     4801 tattacaacc acacgatttt tgaattcatt acagaggtgg atcagtctga gctgacgatt
     4861 tgtgctggtg gtcgctatga tggtcttgtg gagtattttg gtggaccagc aacccctggc
     4921 tttggttttg gacttggttt ggaacgtctt ttgcttatcc ttgataagca aggcgttgaa
     4981 ctgccagtcg aagaaggctt ggacgtttac atagctgttt taggggctta cgccaatgtg
     5041 gcggcgctag ccttgacaca ggccattcgc cgtcaggggt tcaccgtaga acgcgattac
     5101 ctcggacgta aaatcaaagc acaattcaag tcagctgatg ctttcaaggc aaaggtagtc
     5161 atcaccctag gtgaaagtga aatcaaaaca ggtcaagctg tccttaagca taatcaaact
     5221 cgtcaagaga tgacagttag ctttgatcaa atccaaacaa attttgccag catttttgca
     5281 gaatgtatcc agtaaagcaa aaaaactgaa aaaagtggta tgagtcatta agatactaaa
     5341 aaatcacaca acgtcgttgc tttaatagca atgatattgt gtgattttgt gatgttatac
     5401 ctatactaag gactattttt cctattttta gtagtcagtt tgaaagcact cttgtttgga
     5461 atggcagcag ctatgcttat agctggtgat gggttaatgc tattgttgag aaactaaaac
     5521 aatgttagag aagataatgc tgactttata gatgttattg tctatggttt gctggtatag
     5581 tccataatac tgttgaacaa ttttttgaac atttttaatt cccaatccgt cttttttccg
     5641 ttgacttctg gaggcaagct cttttggatc aaaaaagttt tcgatatcaa tgtggagttg
     5701 atttttaaag agtctcacct ttaattgtat ttgtttttca gctttatttt gattgcgaat
     5761 agttgcggca atgctattat caagtagatt tcctataatg actgaaataa cttcagtctt
     5821 taggcttatg tttgtaggga taaggcagtg aatatctaac acaatgccat tctttttggc
     5881 tacgactgct ttttgattaa gtaaataatt taaaatagta tcattggtaa agaaagtatc
     5941 tgtcccatct agcaggttaa ggttatgatt cagtaattgt tgggctttag tgtactgctt
     6001 ttgctccaga agtcctaata ggacaatgtt ttgattatgt agatcatgct taagagccct
     6061 aatgcttaat tgattttcct ttacattttc taaatgcttc agttctgact ggaatcgtac
     6121 cctatctaag ttaatgtctt gcatttgtaa atgctgatct gaaatgtaag tatacagata
     6181 cagcgaagtg attgtgataa tgataaatcc aagtgttagc agtattgtaa acaagtcaaa
     6241 taaaggttct tcttttaatc gaaggagctg tagcagtagc agagaaagac ttatcattgg
     6301 aataatagat agctttagta tccagttggt ttgtgtttgc tcatcaagcc aattgtctgt
     6361 agtctttaaa aagagctgct ttaacacaaa tataatgata atactggata tggtaagcag
     6421 gtttataaat aaaaatgtcc cactgataga agagatttga tatttaagag atattaaaat
     6481 gatccctaag cttgcttcta gcaggatacc tatgctttga agtgtaacag accaaaagat
     6541 acactgtttc atggagtaac gatagctact agatattatc agtgatgtta ccaaagaaca
     6601 agtcagggtt atcagtgagg catagcttcc tgatacaaaa aaatgagtgc agcattctat
     6661 gaatactaaa aaagagagat aacctatgtt tttaaaggta gctagctgac catttttctg
     6721 acgaaaaaaa taattaacaa tcacaatatt aacaactgat gtataaagat gaaaaatagc
     6781 gttaatagcc atttactctc cttagcttgg aaaagatgtt ctcctgaata cccttcttaa
     6841 atttccgact gataggaatg ataaaaaagc gcgtgttatc aatagctaat gttatgtcat
     6901 tgttttcaaa tttatagaag taattgacgt taaacacata agaatgatgg gtttggataa
     6961 attgttcagg aagctctttt agtaatgctt tggttgataa aaaggtagag taggtcttgt
     7021 ccttggtatg aatgagtact tttcgtcctt ccttttcaaa atagataata tcgtttaagc
     7081 ttaagctata gtaggagtgg caagatgaaa aggtaaaaaa ttttttgtca agctctaaaa
     7141 cccttagagc tctatttagg cactcaaaaa aatagggttc atttaaaggc ttaatcaggt
     7201 aatcaaaggt ttgcacgtga aaaatgtttt ccatgtattc tttgtggctt gttaaaaaga
     7261 taataatagc agagagatta tctttcctaa tatgctcggc taatgctatt ccagacatgt
     7321 tatccatttc aatgtcaaga agaaaaatat ggtaatcatt agacagtgac tgtattaatt
     7381 gacaaggatc ctcgtaaatg tctaactcca ctggaactaa ttgattatat tggtataata
     7441 gatcttctac agctgttgca aaagctttat tgtcatcaca aagagcaatt ttaagcatgg
     7501 tacccccata atcctataga ctgtggtatt tagtatacca aaaatgacat gaaaagcgct
     7561 attttttaca aaataataat aatagactga atgttttgat aaaatgaatc tatgaaatga
     7621 gggagcaata atgactgaag taacagtgcg taaaccgatg gaaacaatgg aagtttcatg
     7681 ggtagtcatt taaatactct aaagtgggct gtttttatca gcctacttta atatttttag
     7741 gagggtaaaa aatgaattat agcagacctt gtattaaaga tatttatcca atttataaac
     7801 tgagtgatac catgtttcga ataggcgctc aaattaatat tacgacggaa tttaacgatt
     7861 caaattatga aacaggtgct tcatttacac ataagctttg gccacatttc aaagagtgtc
     7921 cggcttgtgg tcatggcaac agtaatgatt gggaaatatt tagtcattat gggtaggagt
     7981 taatcaatgg aacaatatga attaatggtg aggtcacttt caaaaaggta tgccagagat
     8041 ggctcttatg ccaataggga tttacattgt gtctttaaat ccagtgaaat aacagccttg
     8101 ataggtcata atggagctgg taaaacaact ctactaaacc agattattgg taatataaaa
     8161 cctgatgtgg gtgatatttc atttctagac tgttcgtttg tcaagtcccc taaaattgct
     8221 agaaaaaata cgtcaatgat gcctcagcta catgccccct taaaaggaat cacaattaaa
     8281 caggctattt catcaattgg aaaaatcaga gggctgtccg gaaaattatt ggagacagag
     8341 gttcaggaat taattcaaga actcggtctt attaagtggc aaaatactgt cggagagaaa
     8401 ctctctggtg gactaaaaag attgacgtcg tttgcaatgg ctgttattgc tgctccgaag
     8461 attgttttac tagatgagcc gacaaatgat gttgatccta taagacgtat aaaattatgg
     8521 ttatacttaa aaaagatggc ggcaaaggga catatcgtta ttgttgtcac ccataatatt
     8581 ttagaggttg aaaaatatgc agatgcttat tatttgcttg aaaaggggga agtaaaaagt
     8641 tcaggagcgg taaaaaccct atccagcaat ccaaagagta gaatatccat tttatttaga
     8701 gatcaaaaag ccttggaaga atacccattt gcttactcac ttggtgggga tgacaatgaa
     8761 gctataacaa taatggataa taaggaaatg acagcattat tgaattggtt aggcatacat
     8821 ttgtcatcag ataccattgt tcaatatagt atcacgacgt tagggttaaa tgattattat
     8881 gaggagctgt cagatgaaga agattagtgt tacttaccaa tttctaagct tgttaaattg
     8941 gagctttatt cgccataaat cgttgatatt attgtgtagc gttattcaat tttttatgac
     9001 aattgcactg gtttacggtt attcacttat tattgctgat gatactgtgc aaacagtcta
     9061 ctatcttgct tctggctcag taacgattgg tatgattacc attggctgta cggtatcagc
     9121 acaatcaatc agtagtgata aaagagatgg cattgtgagc tatattcaaa cgttacccgt
     9181 cctaagaagt ttgatcctgc tatctgatct attgatttgg acattaactg ctttgattgg
     9241 tgttggtgtg tcaattgcgg ttgtttattt aaaatttcaa atattgcccc agctgtcctt
     9301 agcgacgttt cttattttgc cattagtttt aatgacaatg atcagtatgg gttttgccat
     9361 tgcttattgg tcaactccaa gtacgatgat gctggtaacc caattattgt tgatgattgg
     9421 cttattgttt tcacctataa tgtatcctgc agaacgtata cctgaggtga ttttaagggg
     9481 atatcatttt ctgccattta taccagcagg agacttgatt cgagagacgg tttatttggg
     9541 gcattccatt tcagttgtca agcttgtggt gttactgtta tggctggttg ccactgcctt
     9601 actttcagtc aattggctaa acaggcaaag ctaaggtata ggctctgcta tttcttaaaa
     9661 actctactca aatgggtggg gtttttaatt gttttttgtt ataataagtg gtaatgatat
     9721 ttttaattag agaaaggaac aaagacaggt agggagtgtt gactctttat ttgctcttgg
     9781 tatcttattt atgaagcgta gcatgtatgc aggacacgtc cgaaaggaac atattggaag
     9841 aacgattgtt ttaaaaggtt gggtaagtcg ccgtcgtgat ttgggcggcc ttattttcat
     9901 tgatttgcgt gatcgtgaag gagtgatgca gctggttatt aatccagagg acgtttcagg
     9961 tgatgtgatg gcgactgctg agcgcttacg cagtgaatac gtgattgagg tggaaggaag
    10021 tgttgaggcg cgtcagcagg ctaatgataa gctagctaca ggtgcagtgg agctaaaggt
    10081 ttcaggcttg accattctta atacagctaa aacgacaccg tttgaaatca aggacggtgt
    10141 tgaggttagt gacgatacgc gtttacgcta ccgttattta gatcttcgtc gtccagaaat
    10201 gctggaaagc tttaagcttc gtgccaagac gacgcatgtt atccgtaatt acttggataa
    10261 tcttggattt attgatgttg agacaccgat gttgacaaag tcaacgccag agggagcgcg
    10321 tgattacctt gtaccaagcc gtatcagcca gggacatttc tatgctttac cgcaaagccc
    10381 acaaatcaca aagcaattgt taatgaatgc gggctttgat cgatattacc agattgttaa
    10441 gtgcttccgc gacgaagatt tacgaggaga tcgtcagcct gagtttacac aggttgactt
    10501 ggaaacgtca tttttatctg agcaagaaat ccaagatatt gttgagggta tgattgcaaa
    10561 ggttatgaag gatacaaagg gcatagaggt taagctgcca tttccgcgca tggcttatga
    10621 tgacgccatg aatcattatg gctcagataa gccagataca cgctttgata tgcttttaca
    10681 agacttgaca gatcttgtca aggagattga ctttaaggta ttttctgagg cacaggctgt
    10741 taaggcaatt gttgtcaaag gacatgcgga tcgctactcg cgaaaggaca ttgataagct
    10801 gacagaattt gctaagcaat ttggtgctaa gggtctggca tggctgaagg tggttgatgg
    10861 tgcatttact ggaccaattg ctaagttctt gacaggtgtg aaaagtaagt tgacagagtc
    10921 tttacagctt gagcataatg atttggtctt gtttgttgca gacaccttag aggtagccaa
    10981 caatacccta ggtgctcttc gtacacgtat tgcaaaagag cttgacatga ttgacatgtc
    11041 tcagtttaat ttcctatggg tggttgactg gcccatgttt gaatggtctg aagaagagga
    11101 gcgttacatg tctgctcatc acccatttac attaccaaca gcagagtcag cccatgagct
    11161 agagggtgat ttagccaagg ttcgcgctgt tgcttacgat attgtcttaa atggctatga
    11221 gcttggtggc ggaagccttc gtatcaacca aaaagacatg caagagcgta tgtttagagc
    11281 actaggcttc acagctgagg aggccaatga gcaatttggc ttcttactag aggctatgga
    11341 gtatggcttc ccaccacatg gtggtcttgc tattggtctt gatcggcttg tcatgctgct
    11401 tgctggcaag gacaacattc gagaggttat tgcctttcct aaaaacaata aagcatctga
    11461 tccaatgaca caggcgccta gtctggtatc tgaaaagcaa ttagaggagc ttcagcttca
    11521 aatagaacat catgattaaa aaaacaacct ataggaaaag agtaaaatac ctgattaata
    11581 gaggagccaa aaaaattggc ttgcttcatg ccgtaaaaag catttccaag gagaagtata
    11641 cagagaaaat ttcggcctct ttactctatg gcatattgtc tagtatagct gttaatttct
    11701 ttttccaacc gggccatgtc tactcaagtg gtgcaacagg acttgctcag gttatctctg
    11761 ccatcagcca ccatttatgg ggctttgaga ttcctgttgc tttagctttt tacgtgacta
    11821 acattcctct tttagtctta gcttggtata agattggtca taaatttacg atttttacct
    11881 ttattaccgt tagtatgagc tctttcttta tccaaatcat gcctcaggtg accttgacga
    11941 ctgacccact gattaatgct atatttggtg gcttggttat gggtttgggg atcggtacag
    12001 gcttcaagtc tcgcatttct agtggtggta cggacattat cagtctgaca cttagaaaga
    12061 aaacaggaaa agatgtcggt aacctttcat tgatgatcaa tggtgtgatt atggcttttg
    12121 caggactgtt gtttggctgg cagtatgcgc tttattcgat ggtgactatt ttcgtttcta
    12181 gtcgagtgac tgatgcgatt tttaccaagc aaaagaaaat gcaggcgacc attgtgacca
    12241 gctgtcctga caaggtgatc cacatgattc ataaaaagct gcaccgaggg gtaaccagta
    12301 tcaatgatgc tgaaggcacc tacaagcatg agcataaggc tgttttaatt acgattctca
    12361 cacgtgagga atatagtgaa tttaagtggc tgatgcttaa aacagatcca aatgcttttg
    12421 tttctgttgc tgaaaatgtt agaatcattg gtcgctttgt cgaatcagat gaagactaag
    12481 aaataggtat caatatgcca gctaataaga gcttaaagct taaaaattgt tgttttatta
    12541 ttcttggctc agctatttat gcctttgcct ttgtctactt ttacatggca aatcgtattg
    12601 ctgctaatgg gctagcggga ctgacgcagg ttgctaatgc cttgtttcag atcaatcctt
    12661 caataacggg ttatctgatt aatttgcctc tcgtcctgtt gggtgcaagg ctctttggca
    12721 gacgggcaat ggtgtatact gtgaccggta ttttatcact ttattggttt gtttggctgt
    12781 ttcaacagct cccccttttt attgacttag atcatgacaa tttagtagtg tccttgctgg
    12841 caggaattct tggtggttta ggtggcggca ttgtttttag aaatggtggg acgattggtg
    12901 gctcagatat tattgctaag ctgatagagg ataggtttgg cttgcagctc aatcaagcct
    12961 tattagggat tgatattttt gtcattgtgg tttctttgac ctatatttca ataccgcaga
    13021 tgatgtatgc tttgattgct agctttatgt atagtaggat tgttcatctg gtgcaaaatg
    13081 gtggctattc tgcacgcgga acctttatta tttcagatta ttctcagact atttcacaat
    13141 tcattatgga ggagctcggt agaggagtca cctatttaca tggtgagggt gcttactctg
    13201 gtcgtgagaa acaggttatt tatgtagctc taggtcgatc agatgtacga gagctaaagg
    13261 cctttatagc acaggttgat cccaatgctt ttgtttcttt ctttgatgtt aacgaagtca
    13321 atagtccaga atttattgcc acaaaaagta aataccataa aacgaaaaaa agataaaggc
    13381 tggaatatca cattcatagc ctttgattat gctaatgaaa gcgcttggct attaagctta
    13441 ttgtagtgta gctattaaat ggccgtcctt gagctttcat ctggtaccta acaaatgtaa
    13501 tgaatagtga ggaaagtgaa tgacaaatct tgacaaatgg catcgtgtaa gagagctatt
    13561 attaattgcg gtgggtgttg ctatctatac ctttggtttt gttaatttca acatggctaa
    13621 tgaattggct gagggtggcg tagctggaat taccttgatt ttgcatgctc attttgggat
    13681 caatccggct tattcgtcac ttttatttaa tctgccttta tttatgttag gggctaagat
    13741 ttttggaagg cgctccctag ccttaacgat ttatggaacc gttcttatgt cagtctttat
    13801 ctggctgtgg caaaaggtgc ctatggagct tggtttagag aatgatatga tgcttgttgc
    13861 ggttgttgca ggcttgtttg caggaattgg tagtggcctt gtttttcgat atggagcgac
    13921 aactggtggg actgatatta ttgcccgcat tgcagaggaa aagtttggtg ctaagctggg
    13981 gcaaaccctg ttatttgtag atgccttggt attaacagcc tctctcactt atgttgattt
    14041 gaagcatatg ctctatacat tagtggctag ctttgtcttt agccagatga ttagtgttgt
    14101 tcaaaatggt ggctatacca ttcgtggtat gattattatc actaagcagt cgcaagccgc
    14161 ggcgcaggcg atcttgacag aaatcaatcg aggagtgact tatttaaagg gacaaggcgc
    14221 ttattctggt catgattata atattatgta cgtgacgctc aatccaacag aggtgcgaga
    14281 ggtgaagcgt attttagcag agctagatcc agacgccttt atctctatta ttgatgttga
    14341 tgaggtaatc agctcagact tcaagattcg tcgcaaaaat tttgacaaac caattgagaa
    14401 ggctttacag aaaaaatcca acatgttaaa ataaagaaaa taagcagaaa taagaggttg
    14461 agaaaagcca tgattaacaa ttaactcatt gtcaagcact aatctatgat taacagcaag
    14521 ggattagtgt ctgctttgag gcttgggaat cagggctttt tgtgtgcact ttttcaggcc
    14581 tttctgatga tagaaaggaa taaatatgga agcacttagt attcagcatt acgctttaga
    14641 tacagcagaa aaaaacttat tgacaataga ttctcttaca ttgaatcaag gtgagagggt
    14701 tttcatcatt ggtgataatg gggctggaaa gaccagcttt ttaaagacaa ttatcggaga
    14761 aagcactaac tatagtggct ttttgcaggt gcatggagat attgcttatg ttccgcaaat
    14821 caagtccact agccctcagt caggaggtga gagggcgatg tcttacctaa aagaggcttt
    14881 tcaagcaagg ccttctctgt taattttaga tgagccaagc tcttatttag accatgctaa
    14941 tcgtgattgg ttgattaatc aattgaaacg ctaccgagga accttgctgg tggttagcca
    15001 tgatcggtat ttgatcaatc aattgagtca gaaaatatgg ttgcttgagc atcaaacgat
    15061 caagacttac catggcaatt atgatgatta tcagcgttct agacagctag aggaggataa
    15121 gcagctaaga gcttttctgg aataccaacg aaagactaat caactgaaaa aaagcctgac
    15181 cagaaaaaaa gtgcaggcca acaaaatggc tgtaaagaaa aagtcggttt ctcggtcaga
    15241 ttggaaaacc aattcctttg cgggcagcta tgattcacag gccaaggcta tggcaaaagc
    15301 agctaaagct atggaaaatc gactcactcg aatgaaagag gttaacagtc cgcgcaaaaa
    15361 ggcttgggca aaattaaaaa aggatccaaa cgaaggtgca ctaccaaata ctcttttaca
    15421 cctacaagaa ggtaccctta caagggacca tcagttattg tttgactatc ctggtattgt
    15481 gatcagatca catagcagga tagcgattat cgggagaaac aaggctggta aaagcagctt
    15541 tttagatcag ctggcagccc aggccttgtc tggattttat gcgcaaaatc taaggataac
    15601 ctattttaaa caggaccagg ctgacttgga gccggatcag acagcagtag agctcattag
    15661 tcggcagtcc agccaagata gggtcaccat tttaaattat ctagctatga tgggcattga
    15721 ttatgataag gccaatcaaa aggtagctgt cttatctggt ggggaaaggg ttcgtttggc
    15781 gttagtggct gccttgctga cagatcatca gcttttgatt ttagatgagc cgacaattta
    15841 tttggatctt gtcgctattg aggctttgga gtcttgcttg attgactatc cagctgctct
    15901 tttgttggtt tctcatgacc tagcatttgt taacaaggta gcaacagaaa tttatgaggt
    15961 taaggatcat catttaacag cctatcattt tgaagactag caaaaaagcc taggctagct
    16021 tatcctcgct agcttaggct tattagtcta catttcattt ggtgcctcaa cacccaatag
    16081 acgaagcgct tctttgagga cgattgcagt tgcatagcaa agcgctaagc ggttgtcacg
    16141 ttctggatcg tcttcgagga tacgggtatg cgcataatat ttgttaaagc tttgtgccaa
    16201 gtgaatagca aattttgcca tgattgatgg ctcaaagtta tcaaaagcac gcttgatgat
    16261 acgtgggaag tcctggataa gcttaatgat ttcccagctt tcaggatcat taaggctata
    16321 gcttgtatcg gtagctggcg taaagcttgc tttacgcagg atagattgga tacgtgcgtg
    16381 tgcatattgg acgtaaggac cggtttctcc ttcaaaggat accattgctt caagatcgaa
    16441 gtcatagcca ttcatacggt ctgtttttaa atcatagaac ttgatagctc ccacaccaac
    16501 agcatgagct actgcttcct tgttggcaag cttaggattt ttagcttcga tttggtttgc
    16561 tgctctgctg atggcttctg caaccgttgg ctcaagcaaa atgacattac ccttacgtgt
    16621 tgataatttt gcaccgccct ttgtcacaag gccaaaagca acgtgtgtca tgtcatctga
    16681 ccaatcgtag cccatttctt taagaacagc ctttaattgc ttgaagtgtg cagcttgctc
    16741 gttgccaacc acgtaaactg attttgcaaa atcataggta cgcttgcggt aaagggcagc
    16801 agctagatca cgagtaatat aaagcgtagc tccatctgat tttttaatga gagctgggtg
    16861 ctcaatacca tatttttcaa ggttaaccac cttagctccc ttagattcga ctagtaggcc
    16921 tttgtcctca agaagctcaa ggacctcatc cattttatca ttgtagaagg cttcaccatt
    16981 atagctatca aagctaactc ctagctggtc atagagtcgg ttaaactcaa tcaagctttc
    17041 atcgcggaac cactgccaaa gctctgtagc ctcttgatct ctctcctcta gcctgcggaa
    17101 ccattcacgt gcctcctcat caagactagg atcagtttct gcctctgcat tgattctcac
    17161 atagagcttt aagagctcat caattgggtg tgcttgaaca gcggcctcat ttccccactt
    17221 cttatacgct acaatgagca taccgaattg cttgccccag tcacctaggt gattgatttt
    17281 aacaggctta tagcccattt ttgcaaagat atgagcaaga ctgtccccga taactgttga
    17341 gcgcaggtga ccgattgaaa atggcttagc aatgttaggg ctggacatat caatagcaat
    17401 atgacgtcct tgtccttcat cctgttgagc atagtcagct ccgtcagcaa tcacctgtgt
    17461 aagaacctgt gcagaaatgc tagccttatc taaaaagaaa ttgacataag gaccaacagc
    17521 agcaaccttc tcaaattggc tggcgtcaat cctttcagct aaatcactag caatagcttg
    17581 tggtgctttg cgaagcgcct ttgctagact aaaggctgga aaggctaagt ctcccatgtc
    17641 agaatttttg ggtgtttcaa gtaagttaaa aatggcagcc tgctctagtt caggaacaat
    17701 cttagcaatc tcagctgcaa tcagagtttt agtgtccata ttgcttctcc taaaaatagt
    17761 ttgtcaccct attctaacac atttcttgga aataaacgag gtgtctattg agaaattata
    17821 ctagaaggct tgtaggtgtt ttggggaaca aagctaaaga attagagcag caaagcttgc
    17881 caaatctaag ggtctaatga tatgagcaag aaataatgct tccttaaaat aaagcaaatt
    17941 gacagagctg agatgaaata ctaccatttt tttgttataa tttgagagga taattataca
    18001 ttggggagat atatcatgaa taaaatagaa cggcagcagc aaatcaagca acttattcag
    18061 gctgagcaca tcggtacaca ggaggagatt agacggcttc ttcaaaagga tggtatcgtg
    18121 gtcactcagg ctaccctatc acgagattta agagaaatcg gattacttaa attaagagat
    18181 gacagaggta agctatacta tagtctttct gagcctgttg ccacaccatt tagtccagat
    18241 gtgcgctttt atgtcctaaa ggttgaccgg gcgggcttta tgctggttct ccataccaat
    18301 ctgggagaag cagacgtgtt ggcaaatctt attgacaatg atgccattga ggacgttttg
    18361 ggcacgattg cgggtgctga taccttactt gttatttgtc gtgatgagga gattgccaag
    18421 cgctttgaaa aagatttagc tgctggtcta taatatgcct taccgcgaat ccttacatca
    18481 gctgatagca gcactggaaa agcactcaag cattatagct tataaggagg ctcagcagca
    18541 cttgcttcaa aggactgatt ataatcaaaa ggcctatcag atgaagcgac atcaacagga
    18601 cacctatctt tttcgtcaaa tcgctaagga taaagcagct gaagaatcag cttttaaggc
    18661 tcagcaatta cgagaagatt tagatcatca accattgata gatgattatc gtgacaaaat
    18721 gcaaaacgct agtgacttgg ttcggtacat tacagggact atagaagatg aattaaataa
    18781 ggagttcaat gatggcaaag gctaatgttt ctcccggaat gcagcagtat ctggacatca
    18841 aaaaggatta tccagatgct tttttgcttt ttaggatggg agatttttat gagttatttt
    18901 atgaagacgc tgttaaggca gcgcagattt tagaaatcgg cttaaccagt cgtaataaaa
    18961 atgctgacaa cccaattcca atggcaggtg ttccctatca ttctgtccaa caatacatcg
    19021 atgttttaat tgatttgggg cataaggttg ctattgctga gcagatggag gatcctaagc
    19081 aagcggtcgg tgttgttaag cgtgaggtgg ttcaggtcat taccccaggg acagctgtgg
    19141 actcaagcag acctgatagt cccaataatt ttttggtggc tgttgatttt gatggcaagg
    19201 cttatggcct gtcttatatg gacgtctcta caggagaatt ttttgctaca gacctagcag
    19261 attttgccag tgtcaaaagt gagattcaaa acctgaaggc aaaagaggtt cttttaggct
    19321 ttgaattatc tgaagaagag caggctattt tagtaaagca gctgaatctt ttgctgtcct
    19381 ttgagatgac agcactagag gattcgcctt tgattgatca tcagctaaca gcagtcgagc
    19441 tgtctgcagc aggtaagctg ctacactatg ttcatcaaac ccagctgcgt gagcttagcc
    19501 atctacaggc cttggtgcac tatgatatta aggattattt gcagatgtct tatgcaacca
    19561 aatcaagcct tgacctgctt gaaaatgctc gtactggtaa aaagcatggg agcctttatt
    19621 ggttgcttga tgaaaccaaa acagccatgg gtatgcgtct attaagggct tggattgata
    19681 ggccacttgt gactagtgag gcgatcctag aacgtcagga aattatccag gtgtttctta
    19741 atgcttttat cgaaaggaca gatctaagcg atagtttaaa gggtgtttac gacattgagc
    19801 gcttgtctag tcgtgtatct tttggaaaag caaaccccaa ggatctatta cagctaggtc
    19861 atactttggc caaagttcct tatatcaagg ctatcttaga ggcctttaac agtccttacc
    19921 ttgacaagct tgtcaaccaa attgacactt tgcctgagct agagcacctg atacggtcag
    19981 ctatagatcc agatgctcct gctactatca atgaaggcaa tattatcaga acaggctttg
    20041 atgaacggct ggatcattac cgaaaggtca tgcgagaagg caccggctgg attgctgata
    20101 ttgagacaaa agaaagacag gccagtggga taagcaatct caaaatcgac tataacaaaa
    20161 aagatggcta ctattttcat gtgaccaact ctaatctagg tatggttcct gaccattttt
    20221 ttagaaaggc aacattgaaa aattctgagc gctatgggac agcagagcta gctaagattg
    20281 aaggacaaat gcttgaggct agagaggagt catctagcct ggaatatgat attttcatgc
    20341 gtattcgtgc tcaagtggag acctacatcg ataggctgca gcagctagca aaagctctag
    20401 caactgttga tgtcctacaa agcttagcag tggtcgcaga gaagaatcac tatgttcgac
    20461 cattatttaa tcaagagagc aagattgcga ttgacaatgg tcggcatgct gttgttgaaa
    20521 aggttctagg tgttcaggag tatattccaa acagcatttc ctttggtcca cagacaagca
    20581 ttcagctcat tacaggacca aacatgagtg ggaagtctac gtatatgaga cagcttgctt
    20641 tgacagtcat tatggctcag ataggctcat ttgtagctgc agaatctgct agcctgcctt
    20701 tatttgacgc tatttttact aggattggtg cagcagatga tttgatctca ggccagtcta
    20761 cattcatggt tgagatgatg gaggctaatc atgctatcaa gcgagcaacc cctcattccc
    20821 tgattttgtt tgatgagtta gggcgtggta cagcgaccta tgatggtatg gcactagccc
    20881 agtctatcat cgaatacatt catgatagag ttggtgcaaa gactatgttt gcgacccatt
    20941 atcatgaatt gacagagctg tcaaccaagt tgacaaagct ggttaatgtt catgttgcga
    21001 cgttagaaaa agatggaaat gtaaccttcc tgcataagat tgccgaaggt cctgctgata
    21061 aatcctatgg gattcatgtg gcgagaatag ctggattgcc agaggattta ctagccagag
    21121 ctgatactgt gctaaccaag ctggaagctc aatcacaagc aagagagtcc gtcttatcaa
    21181 ctacagaagt aagagagact cagcagctgg ctaatcagca gctatcactt tttacagatg
    21241 atggctcctc tagcgagatt attaaaaggc ttgagagtgt tgatgtgatg aatctaactc
    21301 ccattcaggc catgaccgtt ctttatgagc taaaaaagct actgtaaaag ctagtatcag
    21361 atgttaaagg cacttgtagg ctcaccaggc cacaggtgct ttttggttta ttgaccataa
    21421 gacccttgct agctctgatg cttggctctt ttagttttat gttataatag tccataagaa
    21481 tgcgaggaaa tatatgacaa caattatcga attacctgag gttctcgcca atcaaattgc
    21541 agctggtgaa gtcattgaaa gaccagcaag tgttgttaaa gaattggttg agaacgccat
    21601 agatgcaaag agtagtcaga ttactgttga aatagaagag tctggcttga aaatgattca
    21661 aatcactgac aatggcgaag ggatgtctca cgaggacctg cccctgagcc tgcgtcgtca
    21721 tgccacaagt aaaatcaaaa gtcaaagtga tttgttcaga atcagaacac ttggctttcg
    21781 aggagaagct ttgccttcgg ttgcctctat cagtaaacta acgatcaaaa cagcaacagc
    21841 tgatgcagag catgggtcaa tattagttgc tagtggcggt aagattgagc agctggaagc
    21901 tgtctcaaca cctgttggta caaaaatcaa ggtagaaaac ctattttaca atacaccagc
    21961 tagactgaaa tacatgaaga gcttacaagc ggagctggct catgttgttg atgtcgtcaa
    22021 tcgcttgagc ctggctcacc cagagattgc ttttacattg atcagtgatg gcaagcagct
    22081 aacacaaacc tctggggctg gggatttacg tcaagcgctt gctggtatct atggcctgaa
    22141 tactgctaaa aaaatgattg acatttctag tgctgattta gattttgaag tgggaggctt
    22201 tgtgagtctg ccagagctga caagagctaa tcgtaattac attactatcc tgatcaatgg
    22261 tcgctatatt aaaaatttct tgttaaatcg agccatttta gatggttatg gctctaagct
    22321 gatggtggga cgctttccta tagctgtcat tgatattcaa attgatcctt atctggcaga
    22381 tgttaatgtt cacccaacca agcaggaaat tagaatttct aaggagcgtg aattaatggc
    22441 tctgattagt acagctattt cagagagcct acgagaacaa gacttgattc ctgatgcctt
    22501 ggaaaattta gctaggtcca gcacacgttc attttcaaag cctgagcaga ccagtttgcc
    22561 tttacagcct agtcagcttt attatgatcc gcaaaaaaat gatttcttta ccaaagaaac
    22621 agtggtttca gaggatagcc cgcagggctt taaccatgaa actttggttg acagtggtgt
    22681 caagcaggtt gacaatttgc agctggccaa gactgaatct gaagcagctg ctccaagtgt
    22741 taaatatgct agtcggccag atcctatgct ttctgatggt gagcacccgg gtcttgatgt
    22801 ccacaataag caaaaattat ctcagatgct tgatcgttta gaaaatgaag agcagtcggt
    22861 ctttccagag cttgattatt ttggccaaat gcatgggacc tacctttttg cccaaggcag
    22921 agatggcttg tttatcattg atcagcacgc agctcaggag cgcgtcaagt atgagtatta
    22981 tcgtgacaag attggtgagg ttgacaatag cctacaacaa ttgctggtgc cttatctgtt
    23041 tgagttttcc ggatcagatt ttattaatct tcaggaaaaa atgtcgcttt tgaacgaggt
    23101 tggtatttat ttagagcctt atggcaatca tacctttatc cttagggagc accctatttg
    23161 gatgaaggag gcagagattg aatctggtgt ttatgaaatg tgtgacatgc tgctgttgac
    23221 aaatgaagta tccatcaaaa cttatcgtgc tgagctagcg attatgatga gctgtaaacg
    23281 ttccatcaag gcaaaccata gcttagatga ttattcagca agacagctgc ttttacagct
    23341 tgctcaatgt aaaaacccct ataactgccc acatggtaga cctgttttga ttaacttcag
    23401 caaggcggac atggaaaaaa tgttccgtcg tatccaagaa aatcacacca gcttgagaga
    23461 attgggcaaa tactagagag gatagcatgc gagaattttt ccagttacct aagcaaatac
    23521 aaattcggca atttgtgcgc tttattacca ttacgcttgg cagtagtatc tttcctttta
    23581 tggcgatgta ctatacaagc tactttggcg ccttttggac aggcatacta atgatggtga
    23641 ctagctttac aggctttatt gggaccttat atggaggtca tttgtcagat gctattggtc
    23701 gtaagaaggt aattatgctt ggttcagttg cgagcacctt aggctggctg ctgaccattt
    23761 tggccaatgt tccaaagacg gttcttcctt ggttgacctt tgtgggaatt ttgctggttg
    23821 agcttgcttc cagcttttac gctcctgcct atgaggctat gctgattgat ttaacagatg
    23881 atagcaatcg tcgctttgtt tataccatta attactggtt tattaatata gccattatgc
    23941 ttggtgcagg tatttcagga cttttttatg atcggtattt cttagaactg ttgattgctt
    24001 tactgattat taatatcgtc tgctttggta ttgcctatcg ttattttggt gaaacgaggc
    24061 ctgagcatta ccgctttgag catggtattg gtattctagc aggttttgct aactaccggc
    24121 aagtctttaa ggatcgcgct tttgtgttat ttactatagg gacgatttta tttagcagta
    24181 tttggttgca gatggacaat tacgttccgg ttcaccttaa gctgtatttt gaagagactg
    24241 atgtgctcgg tattcatctg actagctcaa aaatgctgtc actgatggtc tttaccaata
    24301 ccttgctgat tgtgctgttg atgacagtta ttaatcgctt gacagcaagg tggagattat
    24361 taccacagct ggtgatcgga tcggttattt ttgcctttgg tatgctgttg tcatttacat
    24421 ttactggctt ttttgctatt tggtgttcag ttgtggtgtt taccattggt gaaatgctaa
    24481 atgtccctgc caatcaagtg ttaagagcag aaatgatgga tcagtctaaa attggctcct
    24541 acacaggctt tgtctcgatg gcccagcctt tgggagctat tctagcaggt ttgctggttt
    24601 ctcttagtca ttttacagga caggctggtg ttcagctagc atttgttttg attgcctgtg
    24661 tggggcttta tgtgattgtt ttatctgcga aaatgaagaa aaaggtgtag tatgtacgat
    24721 tatattaaag gtcagctaac aaaaattact gcaaagtata ttgtggtaga agcaaatggt
    24781 ttaggctata tgataactgt tgccaatcct tatagcttta cagactgtgt caaccagcag
    24841 gtaacgatct atcttcatca ggtgatcaga gaagatgctc agctgctgtt tggttttcac
    24901 agtgaggaag aaaaggacgt ttttttgaag ctgatttcgg tatcaggtat cggaccgacg
    24961 actgccctag ctattgtagc tgtagatgat aatagaggac tcgtcaatgc cattgataat
    25021 agtgatatta catatttgat gaggttccct aaaatcggaa aaaaaacagc tcagcaaatg
    25081 gtgcttgatt tagcaggtaa gttcgttgaa gcacctaagg aggaaagcag caagccccct
    25141 aaagccaagc aacaggggaa tgaacagctt gatgaggctg tcgaagccct attagccctt
    25201 ggatataagg cgacagagct aaagaaaatt cgagccttct ttgagggaac aagtgagaca
    25261 gctgagcagt atatcaaatc agctctgaaa atgctaatga aaggctagga gcttcatatg
    25321 aaacgttgcg catgggtacc acaagataat aagctttatt gtgattacca tgacttggag
    25381 tggggaaggc ctgtctatga tgatcgcgct ctttttgagc tgctttgtct tgaaagctat
    25441 cagtcaggct tatcttggtt aactgttttg aaaaaacgtc cagccttcag aagtgttttt
    25501 catcattatg atatctcagc tgtggcaagc tttagtgagc aggaaatggc tgctgccctg
    25561 caaaatgcag caattatccg acacaagcca aagctaatag ccactgtcaa caatgcagcg
    25621 gcagtccagc gcatccaaca agagtatggt agcttttcca gctatctttg gaactttgta
    25681 ggaggtcagc caattgacag gcttgtcaac gatgacaacc cagcgcccgc tcaaacagcc
    25741 ctatctctca agctatctaa ggacttgaaa aaacgtggct ttaagtggct aggaccaaca
    25801 actgtttatt cctttatgca ggcagcagga ttggtcaatg accatgaaga gaactgtgag
    25861 tttaggtaga attaatcgcc tctttggagt gatgtttcat gagcctatca aagagagctt
    25921 gataaaaaca gcccaatctt gattgcttat aggatgatgt ataagagcta tgtttttgct
    25981 ccgtacttta aggatagatg atgaatcccc ttatttaccc tgtagcgaat gttgtaagct
    26041 tctaatgggt ttaaggtttt agcctgttac tgctattgcc agtaagctac agtttgatca
    26101 ggtagttata ttggattgcc tcaacgattg tgttgctgct ggctggtgct tctttctata
    26161 acttattttg gtgcatgtga ttgtggctct aaaagttata acagagtatc ggtacgattg
    26221 gtgttacccc ttggtttcta tttttttctt atcagccagt ctggcattta cagcctataa
    26281 taaaagctac cgcttaaaaa tttcttagcg gtagtttttt agttcatgtt gcaaggtttc
    26341 tagaagttca gtttcttctg tcaactgtag taattgtaag cctttattaa ttaggtgatc
    26401 atcattacga caaataccga gacgaacttg ggaaaaacct aagctatcat agcgtttaag
    26461 ctgtctagct aatttgattg ttagtaaggt aatttcttcg cactcctttt tgaggttgtg
    26521 atagaggtaa atggttgaaa gattggttag taaagcatat tcagatgatt tgatattgcg
    26581 gtaatcttta tattttgcta ggctatctag gattttttga ctgatgtttt caattatttc
    26641 gataggaaag tgaaaaagaa tggtatgtag taattgtaaa tctttctcat accaagtatc
    26701 ttgttttacg agggaattcc agattttata agctagctct tgtaaatctt gattgttttt
    26761 aacgcctttt ttcctaagac ttatcatgac ttcgacacta tctaaaatat aagaaatggg
    26821 aatatcattt ttatttttaa ggtaattgaa gcatttttga cgtaattttt ctaattcagt
    26881 aatatttaca gctgatacct gattataaaa ttggtttaaa atgtcctgcc ttgtgctagg
    26941 atgataagtg ttgcagacat atctaaactc ttccagtgtc atattgagtt ggtttaataa
    27001 aaaaatcatt gtatcaaatt taggaatgac ttgtccgctt tcaatacgag ctagtgtaga
    27061 acgagctaaa aagtctccac agatcttttc ttgtgttaat cctttagatt ttcgtatagc
    27121 ttgataaatt ttaccgtaat cccaacgcat aaaacacctc taaaatgtta ctaaatgcta
    27181 caaaaaaata aaatctacaa tagtatttta taatagcatt tagaaagagt aaaggaggaa
    27241 aatttatgag gagacatcta aaggttgtat tattacttgc agcactattg gcatttattg
    27301 taaatgaggg taattttcca tggtggcctt ggggaccata gtacttaact gattactgtt
    27361 atgttgttgc cattagacta tctagattaa tcaaagagta aaatacaagt agcttagtga
    27421 aagacatttt aagaggagaa aagcatatga agaaacgttt agcatttata ttagttgctt
    27481 ttggtatttt gggatttagt ttaggaaatg aagttttagc tgcagatact gcacctgcaa
    27541 gtgcaactat ggcaacagat agtgatgtga gtttttacaa tggagaactg ttgaaaaaat
    27601 atttggtcca aagtggtgat agattgtatt ttgattatga caaagctatt caagataaag
    27661 tttctgatgg tgtaatagat atgggattcc ttgttgagac aattagtgag gactattcac
    27721 aacaaacgtt tacctctcga aagtatttca aggcaggatg gcagctttat ggtaattatt
    27781 gtggacctgg ccataacgga aatcatttta ctttacctgt tattgatgtt ttagatcaag
    27841 gctgtcaaaa tcatgacagt tgttatcgat ggggagctgg gattggtgca aattgtgaat
    27901 gcaatcgtca gttagtaaat tacattaaag tatatcgacg gtggatgcca gctcatgcct
    27961 tgggggttgc tgatgctatt agagtatatt ttgaaacggt aggtgctatt ggatgttaac
    28021 cttaaaaaat attatcaatc gatactacat gtattatgta ttccttattg ttgtgatctg
    28081 gattgggatg ttttttgtac gatgggatac tactgtggct ggtgtattac tctatccact
    28141 gattatgaag caggtattta tcgtactagg agtagttgcg atgataatgg ccattatttc
    28201 tagaaaaatt gttcttggaa tttttggttt actatgctgt gctgcttttt ggattaatct
    28261 tttcttagct ttctatctat tacctggact tttgggaaat tagcgattaa actgtttttg
    28321 atgttttgaa gatgagaaac agattgtttt tctgtaaggc ttcctgttac ttctcaaatg
    28381 ctttggagta tctctttatc atttgttcac tgttgacaac gttaaaaaga ttattccaaa
    28441 catgggaatt gctgcttcag ggtattcctt gttaatattg gattgattag ttgttattta
    28501 tgcaaaatcc ttagagcatt gctttctcat tcttggttca tttgaataaa atgtaactaa
    28561 aaaaactttg taatcaattc aaattgtcac aagtataaaa gtaaaaaagc gactttgtta
    28621 gtgatctgat attcggaagt cctatcattg ctcgcttttt gttttttgag gttgattttt
    28681 attccgaaat tgttgtgaat aagtgcaatt ttaagctaag aattacctaa aatcttttga
    28741 agattactgc ttagcttcta atacctattt atcggtgtgt tgataattgg agagatagcg
    28801 ggattgtcat atgaaataaa ttttagaaaa tttaaacaag ttattctgat tattattatt
    28861 tcaacataag tctttatttg attatcattg aaaaccatta attcatctaa aattatttca
    28921 atgcttcatg gatgattctt tttttgttaa aatgagattg aatgtcgaat agataagtag
    28981 gtgggaaaat gaaagctgaa ctcattgcgg tgggaaccga gattctgact ggtcagattg
    29041 tgaataccaa tgctcaattt ttatcagaaa aaatggcgga gcttggtatt gatgtttatt
    29101 ttcaaacagc tgtaggagat aatgaagagc gtttgctttc tgttattgat attgctagcc
    29161 agcgaagtga tttagtgatt ttatgtggtg gtcttggtcc aacagatgat gatctaacga
    29221 agcagacctt agctaagtat ctgggaaaag ctttggtctt tgatgagcag gcaggtcaaa
    29281 aattagatgc tttttttgca catcgtaagc aggctgctag gacaccaaat aaccaacgtc
    29341 aggcgcagct gattgaaggc tctattgctt tgcaaaatca aacaggactt gcagtaggtg
    29401 ggttaataac tgtagatagg gtaacctatg ttgtcttacc agggcctcca agtgagctaa
    29461 agcctatggt aaaaaatgag ctggtgcccc ttctttcagc tagtcatgcc agtctatatt
    29521 caagagtgct gcgttttttt ggcattggtg aaagtcaact ggtgactgct ctggaggatt
    29581 tgattaagca tcaaacagat cctactattg ctccttatgc aaagaccggc gaggtaacac
    29641 tgcgactatc cacaaaggct gacaaccaag cattagctga tgaaaggctg aatcgactag
    29701 aggcgcagct cttatccata agaactgtag ataatcaacc cttacggcgt ttgctttatg
    29761 gctatgggga ggataattcc ttggcgcgtg agacctttga gctattgaag cgaagtggta
    29821 agacgataac agcagctgaa agcttaacag caggactgtt tcaagctcag ttaactgatt
    29881 ttgcgggagc ttcacaggtg tttaacggtg gctttatcac ctacagcatt gaagaaaaag
    29941 caagaatgct tggcattcca ttgggtgagc tacaaaggca tggtgttgtg agctctttta
    30001 cagctgagca aatggctgca caggcacgct gcttgaccaa ttcagatatc ggtattggtc
    30061 taacaggtgt tgctggtcca gaggcactcg agggacagcc agcaggaaca gttttcattg
    30121 gccttgccac taagaataag gtagaatctc ttaaagttgt tataggaggc cgtagccgtt
    30181 tggacgtgcg gtatattgct gccctatatg cttttaatat ggttcgtaaa actttattaa
    30241 aatcagagaa tttgctataa ttaggatagt gtattttagg aaattagtaa ctagacagat
    30301 gtgaggttat gctgtttatt gcttgctagt cagcctaaat agaggagaaa atattggcaa
    30361 aaaaagttaa aaaaaatgaa gaaatcacca aaaaatttgg tgatgaacgt cgtaaagcac
    30421 ttgatgatgc gttaaagaac atcgaaaaag attttggtaa gggtgcggtt atgcgccttg
    30481 gtgagcgtgc agagcaaaag gttcaggtga tgagttcagg cagtcttgct ttagacattg
    30541 cgcttggagc aggtggctat cctaaagggc gtattattga aatctatgga ccagagtctt
    30601 ctggtaaaac aacagttgcc ctgcatgcag tagcgcaggc tcaaaaagaa ggtggtattg
    30661 cagccttcat tgatgcggag catgccttgg accctgctta tgctgcggcg ctgggtgtta
    30721 atattgatga gctgcttttg tcacagccgg attctggtga gcaaggactt gagatagcag
    30781 gtaaactgat tgattctggt gctgttgatt tggttgttgt cgactctgtt gcagctctag
    30841 tgcctcgtgc tgagattgat ggtgatattg gtgataacca tgttggcttg caggctcgta
    30901 tgatgagtca ggcgatgcgt aagctttcag cctcaatcaa taaaaccaag acaattgcga
    30961 tctttattaa ccagctgcgt gaaaaggtag gggttatgtt tggtaatcca gagacgacac
    31021 caggtggtcg tgctttgaaa ttctatgcct ctgtccgtct ggatgttcgt ggaacaacac
    31081 aaataaaagg aactggagat caaaaagaca gtagtattgg taaggaaacc aagattaagg
    31141 ttgttaagaa taaggttgct ccgccattta aggtggctga ggttgaaatc atgtatggag
    31201 aaggcatctc acgtacaggt gagctgatta aaattgcttc agatttagac attattcaaa
    31261 aggctggtgc ttggttctct tataacggtg aaaaaattgg tcagggctct gaaaatgcca
    31321 agagatattt ggctgatcac ccagagctgt ttgatgagat tgaccataag gtgcgtgtta
    31381 aatttggctt gcttgaagat actgaggaaa gtgcagctgc agatacagtt gcagccaaag
    31441 cagatgagtt ggttttagag ctagacgatg ccattgaaat tgaggattag tgcttagtat
    31501 tagattttca gataaaggtg ctaaaaaggg cttaacagcg atcgtcaagc cctttttagc
    31561 ttgtgtttaa tcaagctctg tattggtctg ctcaggagct aggctgtacg cttggataat
    31621 ttgttagctg agtttatgtt ttctttaggg attaactgtt aagctataaa agccctagaa
    31681 aaaagggact tcctacagac aagatagtgg catagtaagc ttgcttgcaa ctagctcaat
    31741 ataggatttt ggccttggtt aaagggatca taaaagaaaa ctaaaaaata ggtccaaaga
    31801 ccgatattga ttagaaaaaa actatgctac aatagaggta tcacgagata gaaagtgaga
    31861 acaacatgat aaaaatttac acgatttcaa gttgtacgag ctgtaaaaag gctaaaacct
    31921 ggctgaatgc ccataagctc ccatataaag aacagaattt aggaaaagaa cctctttcaa
    31981 gagaagaaat tttagctatt ttatcaaaga ctgaaaacgg tgtggagagt attgtctctt
    32041 ctaaaaatcg ttatgccaaa gccttaaatt gtgatattga cgagttaagc gtaaatgagg
    32101 ttattgattt gattcaggat aatccccgta ttttaaaaag tccgattctt atcgatgaca
    32161 agcgtcttca ggtgggctac aaggaagacg atattcgtgc ctttttacct cgttctattc
    32221 gtaatattga aaatgcagag gcgcgtttac gcgctgcctt ataaaaagct ctgtcagagc
    32281 tttttttaat atcctaacaa atctgaattc ttgtttattc aataaaaata agctataata
    32341 gagcgtagca cttaaagtta gaaagaaggt gtaagtatgg gatttacaga tgaaacagtc
    32401 cgctttaatt tagacgatgg tgataaaaag cagattagcg aaacgctgac ggcagtttat
    32461 cattcactag atgaaaaagg ctacaatccg attaatcaaa ttgtaggtta tgtactaagc
    32521 ggggacccag cttatgttcc tcgttacaat gatgctcgca accaaattcg taaatatgag
    32581 cgcgatgaga tcgtagaaga gcttgttcgc tattatttgc aaggaaatgg aatagatatt
    32641 agatgagaat aatgggactt gatgtcggtt ctaagaccgt cggtgtggca attagtgatc
    32701 cacttggttt tactgcccaa ggactagaga ttattaggat caatgaagat aaacaggatt
    32761 ttggctttga tagattagct gagcttgtta agcaatatca ggttgatcga tttgtcattg
    32821 gcttgccaaa gaatatgaat aacactagtg gcccacgtgt tgaagcaagt aaggcttatg
    32881 gagataagat tgaggagctc tttcacattc cggtttctta tcaagatgag cgcttgacaa
    32941 ctgttgaggc agagcgtatg ttgattgagc aggcagacat cagtcgtggt aaacgtaaaa
    33001 aagtaatcga taagctggct gcgcagctga ttttacagaa ttatttagat tgtaactatt
    33061 aaggagaaca gatgacacat aatcatgatc acgaacacga agtcattaca cttgtcgatg
    33121 agcaaggaaa tgaagcattg tttgaaattt tattaaccat cgatggacgt gaagaattcg
    33181 gtaaaaacta tgttttacta gttcctgctg gttcgcaaga ggatgaatca ggagaggttg
    33241 agattcaggc ctattcattt acagaaaatg aagacggaac agagggtgat ttacagccaa
    33301 ttccagagga ttcagacgct gagtgggata tgattgagga agtctttaat agcttcttag
    33361 acgaagagta acaacctgag gcattagctt taaaataata aatagcctag aatcttggtg
    33421 ctagcagcat gggttttagg ctatttttat ggtttatcag acagtaggag tgatagctat
    33481 ttctatgacc tctaaatagc ctactgttaa gagtgttttt agggtcttgt agatgttgca
    33541 atagcctgta atttcgttga agttacttgc tgttgtcttt tttagtttaa gccttaacaa
    33601 agcttatagg aaatgactca acttagcaca gcataagccg cttattttga taagtaaaga
    33661 aatagccaat agctactttt agcttaaagc tgatcattac cagtaccctt agcttttctg
    33721 ggtattattt cgaataatct taatgggggt gattttatca aaagactcag tcaagaagaa
    33781 aaaagctttc taaagcatta taggctaaag acactgcacc gctttaaaga gctgctgact
    33841 tatgccagca tttgtcataa attgactaaa taatagattt tgctatactt gtaatatgac
    33901 atgtcaagga gaaacacatt gagtcaatta catcaagaag ttatgctgga aaaggtcaat
    33961 tatttggtga aagaccaccc atcgtcacat acgactaagt atgacatgaa ggtccctagt
    34021 ttatataaat tttatatctt tttctttagc atcatagcga gcttgcttac ggttgcggtt
    34081 cctttttttg cagatactgc aaatagcgtt cagtcacaaa atttatacat cggaatgatg
    34141 ttgactaaag gtcagattcc atatagtgac ttgtttacaa caggaggctt tctgtttttt
    34201 gtgctcatag ctttgagcta tcacttggga acaacggtat ggttggtact tgttcaagcg
    34261 ctgtgctttt atttgacagg tgtttatttc tataaattaa tccattatgt gacaggtatt
    34321 cagaaggtgg ctttaggttt tacagctatc tattacctat tgtctattag tcttggattt
    34381 ggtggcttat atgcgatcca gcttgccctg ccttttgtct tggtatcgct ttggttttta
    34441 accaagtatt ttgctggctt ggtaaaggac gaggccttta ttctctttgg ctttgcagcg
    34501 gcaatagcca tgctaattga gcctaggacg cttctttttt ggctgcttgc ctgcattgcg
    34561 attattgctt ataatgtgtc tcaaaagcat ttcgctcgag gcttttatca gctgttagca
    34621 gctatttttg gaatgctttt ggtgttttat acagcaggct attttatcct caatttacag
    34681 attttgagtc cttatttgga gcaggcgctt gtttatccgt ttagttattt tgtgacaggt
    34741 gatttatcgc tgattctcgg tttaacagtc caattaggac ttgttcttgg cttgggactg
    34801 ttaacggggc tgctgacgtt tatgaagcag cctaagctag agtctgatct tgctatgaaa
    34861 tggctactag tctttgttgt gtttagctat gctggtattg cggctatatc gcatgatttt
    34921 catacttatc acctactgcc tttactgcct tatgctttga tcttgctatc aagctctgtt
    34981 ggccgacaat atgaggcagg acttaggatg gttagtcatc gtcgtcgtaa ggggaaaaat
    35041 ggtgcgagac gggttattgc tatttatcta aataagcatt tctacgtgcc agcaatcata
    35101 atgctaggag cggtttttgg cacagcttat cagtatgtga ccagctctgc tattaatcaa
    35161 gagcgttctc agattgctca ctatctaaga cagaggctaa cggaggacca acccatctat
    35221 gtatgggacg atacgtcaaa aatttacctg gaaacgcagg ccaagtcagc ttcacagttt
    35281 gcctcaccct ttgttaatct gaaaaaagag agtcatcaac agatgttaga ggatgagcta
    35341 ctacagaata aggcagtcta tattgtggtc aacaagcaaa aagcattacc aaaggcagtc
    35401 aagaaaatag tgacagctaa ttataaaatt gacagaaaga ttgatgttaa gggctttagc
    35461 ctatatcaga aaaaataaat aaaatcaata tattgtgttg gtataaaaaa acttaacaca
    35521 atatattgat ttttttgtgt ggcgtgatat aatagtcgag taaggagata ggacatgata
    35581 acattagaaa aagacaaagt tattgttcag ccagctatta aggttattaa aagagatgga
    35641 cgcttggtta attttgatgc aacaaagatc tacagtgcgc tgttaaaagc aagcatgaag
    35701 gtaacacgca tgtcaccgct cgttgaagca aagctagaag ctatttctga acgcgttatt
    35761 gcagaaatta tcgagcgatt tcctacaaat attaaaattt atgaaattca aaatattgtt
    35821 gagcatgagc tattagccgc taatgaatat gctattgcta aggaatacat caattataga
    35881 acccagcgtg actttgcccg ctcgcaggcg acagatatta atttttctat tgataagctc
    35941 attcacaagg atcagacagt agtcaatgag aatgccaata aggatagtga tgttttcaat
    36001 acccagcgcg atttgacagc tgggattgtt ggtaagtcta tcggtttgaa gctgctgcca
    36061 gcgcatgttg ctaatgccca ccaaaaaggt gatattcact accatgattt agattatagt
    36121 ccttatacgc caatgacaaa ctgttgtttg attgatttta agggaatgct ggcaaatggc
    36181 tttaaaattg ggaacgctga ggttgaaagt cctaagtcta ttcaaacagc aacagctcaa
    36241 atttcacaaa tcattgctaa tgtggcctcc agtcagtacg gtggctgtac agccgatcgt
    36301 attgatgagt ttttggcacc atatgctgag ctaaatttca aaaagcatat ggctgacgct
    36361 gaaaaatggg ttattgagga gctgcgggaa agttacgcct ttgaaaaaac aaaaaaagac
    36421 atttatgatg ccatgcagtc tctagagtat gagatcaaca cgttatttac ctcaaacggt
    36481 cagaccccct ttacctcatt gggatttggt ctagggacct cttggtttga gcgtgagatt
    36541 caaaaggcta ttttaacgat tagaattaat ggcttaggca gcgagcaccg tacggcaatc
    36601 ttccctaagc tcatctttac ggtcaagcgt gggctcaatt tagagccaga ctcaccaaac
    36661 tatgatatta agaccttagc cttggaatgt gccacaaagc gcatgtatcc agatatgtta
    36721 tcttatgata agattattga gctgacagga tcctttaagt caccaatggg ctgtcgctct
    36781 ttccttcaag gctggaagga tgaacagggg caagatgtta cctcagggcg tatgaacctt
    36841 ggggttgtaa ccatgaattt acctcgtatt gctatggaat caaatggcga tatggataaa
    36901 ttctgggagc tgtttaacga acgattacac atttgtaagg acgctcttgt ttatcgtgta
    36961 gagcgcgtta aggaggcaac gccagccaat gctcctattc tttaccaata tggagccttt
    37021 ggcaagcggc tagctaagac tggcaatgtt gatgagctct ttaacaatcg ccgcgcaact
    37081 gtatcattgg gttacattgg cttatatgag gtagcaaccg tattttacgg tgggcaatgg
    37141 gagcacaacc aagaggccaa agactttaca atcactattg ttaaggaaat gaaaaaggct
    37201 tgcgagactt ggtcagatga atatggctat catttctctg tttactcaac accatcagaa
    37261 agcttgacag atcgtttttg ccgcctagat actgacaaat ttggcgttgt tgctgatatt
    37321 acagataaag aatactatac taattcattc cactatgatg ttcgtaaaaa tccaacacct
    37381 tttgagaagc tagattttga aaaggcttat ccagcagccg gtgcttcagg tggctttatc
    37441 cattactgtg agtaccctgt tttgcagcaa aatcccaagg ccttggaagc tgtttgggac
    37501 tatgcttatg atcgtgtggg ctacctaggc acaaatacgc caattgataa gtgctatgaa
    37561 tgccattttg agggagattt caccccaaca gagcgaggct ttacttgtcc aaattgtgga
    37621 aacaatgacc ctaagacagt agatgtggtt aaaagaacct gtggttattt aggaaaccct
    37681 caggctcgtc caatggtcaa tggtcgtcat aaggaaatct ctgctcgtgt caagcacatg
    37741 aacggatcaa ccatcaagta tccggggata taagccttgg agaataatct cattacacct
    37801 atatcattgt aaaggattgc ttcatgcaag cagtccttta gttatcaaga caggtctgta
    37861 acaaagaaag ggagaaacat gggaaaatac cagttagatt ataagggaat gcagcaagta
    37921 gagaggtttc atgagaaaca ttctgttgca aaaacagaca aaaagtctcg agtacagcag
    37981 cttagagcac aatttttaga aaaagcaaag caatcaaaga aataatggca cactcagtaa
    38041 aggcggtgaa gaatgctaga tattggaatt gttgggttag gcgctatttc acaaaaggcc
    38101 tatttaccct atatgcgtca attaagagga atcaattggc atttatctac tagaaatgcg
    38161 ttagtccgcc aggaggtggg tcagcttttt ggttgcgcaa ggctttacag cactgtcaat
    38221 gagttacttg aggctaagtt agatggtgtg tttatccatg cagccactaa ggctcattta
    38281 gagctggcta gtttgttttt acaaaaagga attccagttt acatggataa gcctttgacg
    38341 gaggatttct ttagcacgca ggctctttat caattagcag ataagcacaa tacctttttg
    38401 atggcagact ttaatagacg ctttgcacct ggtgtcaaga agttgtcaac cctgtcaacc
    38461 aaacgtaaag ttgttgttga gaaaaatgat attaatagac caggtgacaa acagtttaag
    38521 ctttttgact tctttataca ccctttagat acagctttat ttttagttga taggaggctt
    38581 gttgcaggct attttcatta tcagctgact gataatgatt tgctaagtca ggttagtgta
    38641 accttaagga cagaacagac tattatttca gcagctatga atctacagtc aggtagcagg
    38701 cgtgaggtga tggaggttca gacacctaaa gagacctatc acctagaaaa tctagagacc
    38761 ttgcgagctt atcgaggggt tgatcaagag atcaagggat ttagtgcttg ggatactacc
    38821 ttatctaaac gaggctttga ggctattgtg gattcttttt tacaggctgt caaggatggt
    38881 gttaaccctg tcaagccaga gacaagtctg ttgagtcact ggatttgtca ccaaatttgt
    38941 caatctcatg aagctgatgg catattagat gtttctcttc ccttataaag gagtgataat
    39001 atgaagctac gaagacctaa aaagcaagat gaagcgtctg ttttagaaat gatggcagag
    39061 tttgaagact atcagtctcc tcatgatggt ggtttttgga acgctgagca ttttgattat
    39121 gaaaaatggt tggaatctaa tgctctgatg gaggctggct tagctatccc tgagaattgg
    39181 gtgcctgcca tacagctcgt tgcctttgct gatcaacagg ctattggatt tgtcaatgta
    39241 cgcttgagat taaacgaaca gctactggta aaaggtgggc atattggtta ttctgttaga
    39301 cctagccagc gtggaaaggg ctatgcaaag ctgatgctaa aggaagcctt gcagcttgct
    39361 cgtcaaaagg gcattcgtga ggttttagtg acttgtcatt gcagcaatag tgctagtcgg
    39421 tctgttattt tagctaatgg tggtcagctg aaggattgca ataagggtat tgaacgctat
    39481 tggataaaag cataagaggc aataatgaag gaaaactgtt ggaattctcc caaaccaaaa
    39541 gaatggacat cagaggcatt aagccaagga cgcgttattg attataaggc atttaatttt
    39601 gtagatgggg agggagtgcg aaactcactt tatgtttcag gctgcatgtt ccattgtaag
    39661 ggctgctata acgcagcaac ctggtctttt aaggcgggta ttccttatac gaaagagctt
    39721 gaggagcaaa ttatgactga tcttgcaaag ccctatgttc aaggtttgac acttttgggc
    39781 ggtgagccct ttttgaatac gggaatattg attcctttga ttaagcgtat cagaaaagag
    39841 ctgccagaaa aggatatttg gtcttggaca ggctatacct gggaggaaat gatggaagaa
    39901 acccaggata agctagagct gttaagcatg attgatattt tagttgatgg ccgctttgat
    39961 atcaccaaaa agaatctgat gctgcaattt cgtggatcca gtaatcagcg tatcatcgat
    40021 gttaaaaagt cactggctgc tggagaggtg gttatttggg ataagctaaa tgatggtgat
    40081 cagtcctttg agcaaatgag ccgcgatgat ttgatttagt agagacttat caacatcact
    40141 agacttgaaa gctaataatg aaagcatgat tttaggctcc tgtggtcttg cttaaccaat
    40201 ctaataaggg gttttcccca cattatcctc atacttatcc acaggttgtg aataacctgt
    40261 tggtttgtgg ataaaaaaga gaattaaggg gttctttaat tctctaggcc tgaaaaaggg
    40321 ttctttttga tgttttttct taaaagaaag agaggcaagt gacctctctt gaaatagtat
    40381 acttaggctt taagcctagc tttcaatatc tctgaatgtc tgattttctt aggagtcagg
    40441 cattttttaa tggcgatggg aagtacggct tgtgggtcgc tttgtgtgct aagaggcttt
    40501 ctgagctgct atatgtcaat gattggtgat gtgacagctg aggcttgttc acattctgaa
    40561 agcactgatg tttttcctag ctttcttttt tgatgtagta gtaattagtt tcggttgata
    40621 gctcctcatt atagcaaaag ccagcaaagc tcagctgctt aagtgcttcc ttggtttgga
    40681 cattgttttc tagacaggct gttagaaagg ctcctcgagc tttttttgaa atggttgaat
    40741 gcgtcttgag ctgtcctgat ctttcctcca taaatttggg acttatccac agtttttgat
    40801 attcctttga aaaaacatct ctaaactcgt tggataacag agaaatgatt tgcttgtgat
    40861 ctttagcaaa ctgatcgtag atagggcgcc aataatgctt aaggctttgc ccattgatgg
    40921 ttactttagt gtgaaaatca tgccggtgct ctgcgatttt ctcatcagta gggataatgc
    40981 cataaaaaga cgaggtaatg tagacctgct ttgagaggta gtcttgctgg tctttagaga
    41041 gattgtcgcg cttgagatga cggtacatga gcccattaaa gagctgataa gcaggataag
    41101 cagaactctg cccttgagct atggccttta gtctcttggc ttccttgctt gctgcttcta
    41161 tacggatgct gtaggccctt gctagctcct ctagggatag ttcagccata gcctctaata
    41221 tgggcaggct tttttgggga agctgatgtg gatagcaagg tggaactggt ttcatttctt
    41281 tagctgttgg aattaaaaaa gttaacataa gtttattgta gtaaaggcgg caaccttctg
    41341 tcaagagtgg gatacatttg gtggttatgt catatgaaac taatttttat attttttaca
    41401 ttttgattag tttttaaaaa tatagtgatt tagtgttgca taacctctct aagtatgtta
    41461 atatatactc aagtctgttt gataaacaga agctcaggtc aagtgagtgt tccacttaca
    41521 ataacgcagt tgatgatggg gagactcaga ctcagactca gactcagagt caaggaaaag
    41581 aaatatagtc ttgtaggatt acctacaggg cttttttcta ttttgaattg agagatcaat
    41641 ataaggtgat gtgctgtttt ttattacctt aaacatttgg atattggcta ttgacaaaaa
    41701 gtgtaaagga aactatacta tatgtgtaaa gttaacttga catattggag gaaccatgga
    41761 aaatcggata caagaactcc gtaagtcacg agggattagt caagctgatt tggcagatat
    41821 gatgtgtgtc actaggcaaa ccattatctc cttagagaaa ggacgctata atgcgtcatt
    41881 agagctggcc tataaattag cgacattttt caatctgact atagaagacg ttttcttgtt
    41941 tgaagagaag ggagaatgag atgatattta gtgatttaag cgtcctgctg actcaaaaaa
    42001 gccagctagc ctatgccaaa aggctgaagt atatgggctt tttcgctctc tgtttaggcg
    42061 gtttgttttt gttgctggcc tttgacgtga gactgacgag ctttgctcag ggaatgctgg
    42121 tagggcttgg tagtggtagc ttattattag gtgttcgtgc tttttcagat tgcctttaat
    42181 cctcaaaggc tgagagcctc ttatattaag gcttatgatg agcgtcatca ggtagttatc
    42241 aagctagctg ctgtatcaac cttaatctta ttagtggtgt tgattattgg ctgtttgtgc
    42301 ttgaatgttt tttggagttt ggtttttggc tttagagtat ttttagagat ttgtctgtat
    42361 acgatcttgc ttggtttttt aggcatcaag ctattgttag agcatatgat ttaggaggct
    42421 tcaatggaaa caaaacattc agcagtaaag gtcatcatca gtaaattaaa atggtttggc
    42481 ttagctcttc ttgtgtttat gcttgagcag gctccaacat ttttgataac aaaagaacag
    42541 ccaatgtggc agacacttct tcttgtggtc atttttcttt tgattagtgg aggtacttat
    42601 tacctagctg tgaagcttca cattgtggga gatcaagcta ttcctaagaa tgactatcgg
    42661 gcactttgga ttggtttggg agtggtagct gtctttgttg tcaagatgat tggtggtatt
    42721 ctgttgtttt tggagcatgg tccgggagcc aatacggtca atcaagctgc cttagaacag
    42781 gcaggcttat ctccgattct tatggttacg ctagttgcta ttgtggcacc aattgtggaa
    42841 gaaattgctt ttcgagggct gctttatggg aagctctttg gtgcagagtc ttatctgggc
    42901 ttgattttta gcagtatcat gtttggcttg attcatgtgc caacagattt tggcagttgg
    42961 tttatctatg gcggtatggg gctggtgtta ggctttgttt tccataaaac aaagaaggtc
    43021 gaatacacga tattgattca ttttttgaat aatgcactag ctgttcttat catgcttttg
    43081 ctgccttatc ttcagtagta ctgcttgagt aatgaagggg gtaatgaatg aaaaatgatc
    43141 gttggattga caaaaaatat caacgttggg agaaagtgta taagagactt ggtcattctt
    43201 tactgacaat cggtgtgttg gtagggactt atgggatttt tttgattatt caagggaatc
    43261 atcaaacggg ctttctcctt tttatcctgg ggcctatact attgattgcg tcatgtcttt
    43321 gctattatgt gtttacagag ccaacgtctt tacgagaata tctgattaat agctatgatg
    43381 agcgtaaccg agctattcgt cagaaagcac aggcctactg cttttgtcta tttgcttttc
    43441 tctttttgat gcttgcgata ttctttccaa atatgacgat caaggagctt tttgggtata
    43501 atcttccgtt gattgttttc aatctgtatg tcatgattag agcctgggtt agtaaacaca
    43561 tgtaggtcat gttaacacaa aggagtctag agcaagggct ttgaatgaaa ctatttttct
    43621 aaaaacgcaa aaaatcgcgt gcagtaacag attaggccat gttactgcat gcgattttgt
    43681 tgtttcaaac gtgagctcag aatgacatat cctttttaga aagaataggt atttagggct
    43741 gtcttgagct agtcttaggt aatgagcttg gagctcattg gtgatggtta ggataggtct
    43801 ttagcttttt tgatcgttgt gtcaatggca gagcagacag aatgtgtcag gcctgttttt
    43861 tcaagatcca tcaagcctgc aatggttgtg ccgccgggac tgcagatctt atcaatcaaa
    43921 tcatggggac tatctgtgct gactagcagg ttcttggcgc tagctaggac agtttgacta
    43981 acgatactaa gggccttgtc tttaggcagt ccatttttga ctccggcctt tgccatagct
    44041 tcgatgaaaa ggtaaagata agcaggactt gaccctgcta gagcagtaaa ggtatcaaaa
    44101 tccttttcag ctatttcaaa ggttgttcca aagctgttgg ttagctcttt agcagtagct
    44161 aataaatcag cagttactaa gtcattacca gtcaaagcag tggtgctttg gagaatttga
    44221 gcattcatat ttggcatgat acgtaggagt ggcaaatgag agcttgttaa ttgagctagt
    44281 ctgtctaagg aaataccagc agccattgac atgataggct gtttgaactg tagagggcta
    44341 agaacagtct caaagagctg tggcttgatc cctagaatga tgaagtcaac ctgatcgatc
    44401 agctcttggt gagattgggc gtagcttagg tgcaattggc cagcaatttc tttagagcga
    44461 gctaaggatg agcctgagat gattagctcg tgtggtgtgt gtgttaggcc ttgaatgata
    44521 gcagttgcca ttttgccaac accgataaat ccaattttca taataatgtt cctaaaaatg
    44581 aataaaggct caataggcta gagtgctcat tgaaccttag attcgcattt tagccttatc
    44641 cttcctagta tttcttgatt aaatcaactg ttgagcggtc aagctttttg acaatggctt
    44701 gcaaaaaggc ctgtgcttct acgaaatcat ctaaggcgta caagctctga tgtgagtgaa
    44761 tgtagcgagc gcagacaccg attgtggttg aagggatacc gccattttta aggtgagcag
    44821 caccggcgtc tgtaccgcct ttaccacaat aatattggaa ggcaacccca gcctcctcag
    44881 cggtggttaa taggaagtct cgcatgttct taagcatgat gtgtccggga tcgtaaaagc
    44941 gtagaagggt tccatcacca atatgggcag gattgccata aatatcacca gcaggtgagc
    45001 aatcaacagc aaagaaaagc tcaggatcaa atgtagtggc tgacacatgg gcaccacgaa
    45061 gcccgacttc ttcttggaca tttgctccag caataagggt gttgtgaagt gtctggtctt
    45121 ttagggcttc tagcagctca gtgaccatga gaacaccata gcggttgtcc caggcctttg
    45181 agatgatatt ctttttattg gcagttaaaa tggtttcaga ctgcggtaca ataatatctc
    45241 ctggtgtgat gccaaagctt tcggcttcag ttttgtctgt aaagccacca tcaaaaacaa
    45301 tatctgaaac cgctggcaga ctagcagcac catttgcccc gcgcagaaaa tggggaggaa
    45361 ctgagcctga aataacagga atggcttggc cagcgcgagt gtataaggta aagcgctgtg
    45421 agctaacaac tagtggattc cagccgccaa tttcaacaac ccgcagtgtt ccatcagctt
    45481 taatctcgct caccataaag ccaacctcgt ccatgtgagc cgcaacaaga atgcgaggag
    45541 cttgatccgc cttgctttct tttatcccaa atatgccgcc aagtccatca acctccactc
    45601 ggtcaacaag cggcgtgatc ttagcgcgta agtaatcccg aacagtgtgc tcgtagccgg
    45661 cgatgccgtc taattcagta acttctttaa tttttgaaaa taaatcaatc atttgtatac
    45721 tccatttgtc atgtaagatt aaaggtatca cgtctgcctc tattctatca ttttttagtg
    45781 aagaatggga aacagcttga gcataggaaa agagtttggg agattaggtg tgtctttctt
    45841 gcttgataag ctgcttatta tcagtttgat tcagatgaga taactgctgg tattgatgga
    45901 atgaaacagc tatgcacaac agccttgaca aggatcgaca ggcctgagct gtcttatgct
    45961 atcaattgca cttaggtaga gcagtagcct gatattgatg tgattagttg ctcttgtcag
    46021 gtggtttatt agtatttcct aaagtgtcag ctagtcttgg ctgagattgt tagcttttgc
    46081 tctagcctat tattcccttt ttgtgataaa atgaaaggta tgaatggaaa aaagacacgt
    46141 attgtttcag gattaattgg actgggtctg ctagccggct tgggattgag gcttaaggaa
    46201 gtctatcaag aaagagagcg tcagagagta ttggttgaat tgcgcgcctt tttctcagcc
    46261 ttaggagaga ttgaggtctt gtacatcaac tcctttagct caaagcgtga tgatgtcact
    46321 ggtggccttg tcatgacaga tggtaagacc tatacttacc attaccacaa aggaagtatt
    46381 gattttaaag aggatttgac atgattattc caacatctaa ggaagaactt gctaggctaa
    46441 ttgagacaga gcctaggctg gttttgtttt ttacagcaga ttggtgtccg gattgccagt
    46501 atatctatcc tgtaatgcct gagctagagg ctgaaaaccc ggatatgacc tttgtccgcc
    46561 ttgatcgcga tgattttatc gatttagcgc aggattggca aatttttggc attccaagct
    46621 ttcttgttat ggaaaagggg caggagaagg gccgtttggt caatagatta cgaaaaacaa
    46681 aggctgagat tagtgacttt ctagcagcct atcactaaga ggagaaaatg agatgatttt
    46741 tgcatataat aaagagcagg tcggtgatgt tttgatggtg atactagagg ataaaaaaga
    46801 catcaagcga caggttgagc gtaaggggag agtagcgcgt gtttttgcag aagagacagg
    46861 gcaaaccctt gcttggaata tttttgaggc gtcagcctta atcgctgttg agggaaatgg
    46921 gcaggttttc ttgtctgagg aggagttagc gattttaaat gcggagcttg ctcaagaagg
    46981 gtttactgaa cgattagagg ctagcccagc ccctgttttt gttgtggggc aaatcattga
    47041 gatgattcct cacccagata gtgatcattt gaatatctgt caggtacaga ttgctcctga
    47101 taaggctgtg caaatcgttg caggagcacc taatgctgct gttgggttaa aaacaattgt
    47161 tgccttgcca ggtgctatga tgccaagtgg cagccttatt tttccaggaa agcttcgtgg
    47221 gaaggaaagc tttggtatga tgtgttctcc acgcgaattg gccttgccaa atgctccaca
    47281 aaagcgtggt attattgagc ttggtgatgc tgcagcggtt ggtgaagcct ttgatcctgc
    47341 taagcattgg cagagctagc aggacttgat cagcattaaa atggtgttta gtccttcttt
    47401 tgcttggtga aaagcctttg gaccttgagc catgcagtgc tttttgctgg tctgtgactg
    47461 tctttagctt caggatcgaa gcattagagt agctgcttaa cttattgtca gcgctgttga
    47521 ttgcagtagc gctatgcttg tgacaagtga aggcaaagcc tatcaatgcc cttggctagg
    47581 gctaaaaatt gtctttagag tcacttttga ggtgagtagc tcgctaattt cggtattgaa
    47641 cggtgcttag gtaccgtttt tttaagcttt gctgagtgtg acatgctgaa aaaaggccat
    47701 gtctttatat ggcttttggt cacagatggc taattcaatc gtccgcaaca cttccagcca
    47761 atcaggctta gctttaacct catttggttg aagtccgtag catgtccgca gtccacgata
    47821 gccttggagc ttcaaatcgg tctttctgag taagtcatca atactgtagg tctgacctgc
    47881 tgcaaaggat aaactttcaa aggcttgtcc atttagcaca ttaagtgcct tgtcatagtc
    47941 gtgttcaaaa ataacagagt ggagaacttt tccgacttga ttgtgcttga tgagtgatag
    48001 ctgcccttta ggcttcaata gacgttccat ctgagctagg tagatcgcat gctcttttgg
    48061 ggcgatatat tctaagacat tgtggcatat gatcatatca aaggcttgat caggcagttt
    48121 ttctagcgct tctaatgaac cttttatttt atgaatgctt tcttgctttt gggcaaataa
    48181 taggtcagga tttggctcaa ttgcagttac ttcattctgg acggctaatg cctctgctgt
    48241 gatgcaaaag cctgctccga aatctaaaat agtcttgcct gctatggggc ctaattgggc
    48301 aaagatcaaa tcatacatga gctttcccca gggccttgtg agcatgtctt gataggcttt
    48361 aagattaata gtcattatct agttttcctt tctttagctg ctgtgagcta ttggcaggat
    48421 ttctaaactt cacagcttgt ccttatttta ccatgtttta cgaataataa gataaggagg
    48481 tatgacatgt acaataaagt aatcttgata ggccgtttag tggccaagcc agaattaaac
    48541 aagacattaa cggataagca ggtcgttcga tttaccttag cagttaatcg tcggtttaag
    48601 acgacgactg gtgagcgtga ggtggatttt atcaatgctg ttgcttgggg aggtttggct
    48661 gaaaccttgg cttcctatgc tagcaagggg agtctgctgt cacttgatgg cgagcttcgc
    48721 acacgaaaat atgacaaggc gggtcagact cattttgtga cagaggtttt gtgtcattct
    48781 tttcaattgc tggaaagtcg agcgcaacga gctatacgtg aaaacaacgc tgctaatgat
    48841 ttgattgatt tggctttaga ggaggaaaag cttccctttt aaagacagct gctagcttac
    48901 tgtcgctaag ggagtcagac actagcattg tgtatgctag agatctcaac ataatctaaa
    48961 aaatgacaac gattctaaaa aaaatcttga cacgtcttag aaaaaggttt acaatgtatg
    49021 acaattaaaa tgaaagaaaa caggaggtgc tggtatggta gcagttagca cagctcagac
    49081 gatgactaag cgttattact ttagcttctt tagatagtgt ttgtagacat gagcgcatgg
    49141 atacaaacac actgaacgtt atgtttgtat ctatggggct aagggctatt tgagttgttt
    49201 gtccacatag atgatatctc ttctaagtgg acaccataca gcatgtattt tgttatctca
    49261 tgatacctgt ataggaccat ttagattatc tagatggtct tatttttatg caagaaagag
    49321 gaaatgacat gagatttaaa cagttatcct taacagcctt tatagggctt ttggcaatgc
    49381 tgctaacggc ttgtcgacaa gaaaccaacc aaacacatca agctgctaga gttgggatta
    49441 ttcaatatgc tgagcactca gccctagatg ctgcgcgtga gggttttatt gaggcgcttg
    49501 agcagggcgg ctttagagag gggaagaacc tgaccattac aaccaaaaat gcacagggtg
    49561 atcaggctaa cctgcaaaca atggtggagc agctggcggg taagaacgat ttgcagcttg
    49621 cgatcgcaac gccggcagcg caggcgcttt taaatatgga ctcagagaca ccagctgtat
    49681 ttacagcggt aacagatcct gtctcagcag gtctggttga tacattagct aagcctggtg
    49741 ggaatatgac aggctctaca gatgcgactg atgttgagaa tcagattgat ttgttgacca
    49801 aggcgctgcc tcaagctagg acagttggga ttttctacaa ttcaagcgag gtgaattcgg
    49861 agatacaggc taagaaggcc aagagggagc ttgagaaaaa aggcttaaag gtccttatga
    49921 aaaccgtaac cactactaat gatgtgcagc aggttatgac aagcttggct agtcaggttg
    49981 acgctgttta cctgccaaca gataatacgg ttgcctcaac agctactact attggggata
    50041 ttttaaagga ggccaaaatt ccttcaatgg gaagcgatgc tgcttacctg agtgctgttt
    50101 tgttcacctc aggtgttgat taccatgcta ttggcatgca ggctggtcag caggcggtag
    50161 atattttaaa gggtaaaaaa ccagcaagca ttcaggttgc taagcctcaa aaggcaagca
    50221 ttgctgttaa tgatgatatg gcaagacttc tgggcattga ccccgaggtg atcaaggctc
    50281 ttgcaagtaa cggagccaac tagcgtttta ggaggaaggt atgaaaaaag gaagctattt
    50341 aatactgtta gtgcttgcag gcttcgtttt ggtggcttgt cgttcgacag ctagtcctcg
    50401 taaggttaac caatctcatg ttaacatcgg tattttacaa tacatggaac atgattcgct
    50461 gacggcagct cgtcgaggct ttgaagcgca attaaaggca gcgggctata ctaagggaga
    50521 caagctgagc cttcattatc aaaatgcaca gggcgaccaa gctaatttac agacgatttc
    50581 agagcagcta gtgaagcaaa atgatttgat cttggcgatt gcgacaccgg cagcgcaagc
    50641 cttagcgacc gtctcatcag atagaccaat tgtttttaca gcagtaacag atcctatctc
    50701 agcaggctta gtggatagga tcaaaaagcc tggtggcttg ataacaggaa caagtgacca
    50761 ggcgccgatt gcaaagcaaa ttgacttgtt agcccaagcc ttgccagagg ccaaaactat
    50821 tggcatttta tacacagcta gtgaacgtaa tgctgaggtg caggtaaagg aagctgaaac
    50881 gctactgacc aaggttggtt atagggttat taaaaaggga attgccactt caaatgatgt
    50941 gcaagatact gctgcaagct tgatgagagc agtagacgcg ctttttgtac cgacagataa
    51001 taccgttgct tcaaccatga caatgctggg tgagctgtca ttggctaata aggttccaat
    51061 tattggtggc tcaacggata tggttgatgc aggtgggctc ttgacctatg gtatcgacta
    51121 cgagagcctt ggtagacagg ctggagaaat ggccattaag attttaagag gacaggatcc
    51181 agcaagccta gcagtggagt acccaaaaac agtcaagcta catatcaatc aagcaatggc
    51241 agacaagcta gcgattgata cttccacatt atcagttgac taaattgcta ggttaaaggc
    51301 taaatgactg atctctagcc agctggctaa atgacaaagt cttaaccagt tagcttagct
    51361 tactattaac gattcatatg acaaaaaagg agaaatcatg tcactcattt tatcgagctt
    51421 atcacagggc ttattgtggt ctattatggc aattggtgtt tacctgacat ttcgtatttt
    51481 agatattgcc gatttaactg cagaaggttc ctatccgctt ggggcagcta tttgtgcagc
    51541 gggtattgta tcaggtgttt ctcccttgct ggctacgttt ttagctttta ttggaggctt
    51601 gctggcaggc cttgtctcag gattagttca caccaaatta aaaataccag ccttactaac
    51661 aggaattatc actctgacag gcttgtattc tgtgaatcta aaggtgctag gaagagccaa
    51721 tgtggcttta ttacgtcaaa gaactttagt tacccagctc tatgatctag gctttaccaa
    51781 gcttgcagcg gtgctaatta tgggctttgt ctttgtgacc attgtgattt ttttattagc
    51841 cctgctgatg aaaactcagc ttggcctagc tctgcgatcg accggagaca ataatccaat
    51901 gagtgaagcc aatggtatca aaacagatca gatgaaaatc atggggtata tgctatctaa
    51961 cggtttgatt gccctatgtg gtgccttgct ttgtcagaat aatggctatg cagatttaaa
    52021 tgctggtgtt gggacaattg ttattgggct ggcttcgatt atcattgctg aggtgatgat
    52081 taggcagcta agcattggct ggcgcttagc ttccattgtt ttaggctcta ttgtttatcg
    52141 cttaattatt ctagctatcc tagccattcc cggtatggat gcagatttgg ttaagctttt
    52201 ttcagccatg ctattggcag ctgttctttt tgtgccagaa ttacagcaaa ggcttcgcct
    52261 tcgaaaaaca agtttaggat aggagaaatc atgtcagcaa tattatcaat taaggctatt
    52321 cacaaaacat ttgaagcagg tacgattaac gaaaatcatg tcttgagagg cttatctttg
    52381 gacattgagg agggggattt tatctcggtt atcggtggga atggcgctgg aaaatccaca
    52441 ttaatgaata ctctagcagg cactctggct tttgatcagg gcgatattct tttagaggga
    52501 aaatcaatca agcatttatc agccgctaag cgtgccaagg acatcagtcg agtgtttcaa
    52561 gaccctaaga tgggaaccgc ttcacgcttg accattgagg aaaatatggc tattgcttac
    52621 cgccgaggga aatcaagggg gctaggctgg ggcgttaaag aaagagagcg ccagatctat
    52681 cgtcaggcct tgcaggaatt aggcctaaat ctggaaaacc gtcttaaggc cgagacacag
    52741 tttttatcag gagggcaaag acaagccttg accctgttaa tggcttcctt agcaaagcct
    52801 aaggtcttgt tgctagatga gcataccgca gctcttgatc ctaagaccag tacaatggta
    52861 atggctttga caaagcagct tgttgagaca catggcttga caaccctgat gattacccat
    52921 aatttggaaa atgctattgc ttatggtaat cgtctggtca tgctccatca aggtaatatt
    52981 gtggtggata ttaagagaga agagaaggcc aagctgacgg ttgaccactt gatggcactc
    53041 tttcaccaaa atagtggtca tacgctcctt gatgatgcac ttgttttggg ataggctagg
    53101 tgagggttag ctctgttttc aaatagcagc cataatgaaa aggcttaaag ccaacgcttc
    53161 tagaaacgct agctcaagcc ttgttataat acttaggaga tttttctaag agtgataaag
    53221 ccatgatgac gtctattgta gtcaaaggat ttgtttcgga tgcgataagc ctcattttcc
    53281 acaatttcaa ttgccttatt cagctgctga atggtaatcg cctcatcaat ctcatgaaaa
    53341 gcagtgctat aataatcctc actaacacgt tgattgcggt ctttataggt atttttatgc
    53401 tctgttaaaa tggccttagc ctcagcacgt tttgcaatgg tatctataat accttgacca
    53461 tatgctctag cctcttgaag gattgacagc atattgtcta gagaatatgc gtttgctaag
    53521 cggctgacaa agctatcagc gacctcagga cttaaattaa taccatctaa gtgataaatc
    53581 atctctgggt gtagctttag gtaatactgc aattcgcgga acaaaagcgc tggaattttc
    53641 gacgaatccc tatatggatt gagctgaatc tcctgactat gtagcctatt gataaaatcg
    53701 tccttgaact gcttaatagc atcgtagtct gatttttcta gctctgcttt aatattggct
    53761 agaatctggg cgtctgaata acgacgatag cttgatagtg aagcagcagg cctactagta
    53821 ttggaatttc gagaagcttc tgctcttcta gtctctttgc ttggtgtttg ctgcttattt
    53881 gactgagtct cctgctcggt tagtcgtagc tcagggtgta aacgactaat attgttaaga
    53941 aattggttaa cctcatattc tgatgaaaac tttagcctag gtctggcctt gaccttctca
    54001 atagccttgt caataatcct tttcccgtac cttttgagat tactgtcaga ctggatcaaa
    54061 taaagattaa catgtaagtg atcttgacta tccgccttag ataagctgtt accaaggcca
    54121 aggcttccta agagcgtagc tagtaacagc aggtgtttta ctagactacg ctgaacaata
    54181 ttgtgacgac taagcataag ttattttccc attctattgt aatataccag aaaatgttat
    54241 caaaataaag ataagatgtc aatgtcatta atggtggtta atctttaatt aatggtcgtt
    54301 aatctagtat atcagagagc tagcttaggc tggcagtggt cattctgtgc gtcttggtac
    54361 gaaatgccca agcagatgca gctcactaga atgatcaata gcctcaacac aaagcccctt
    54421 acagcttgac acaagctgta aggggctttg ttgtattaac agataactca aatccttgct
    54481 ttttataata aatctaaggt ttttagcttg tcatcaatca tgtgcagaac ggttgccaaa
    54541 tcctctgggt tttgcacgaa atcaagcttg tttccatcaa tcttcatctt aggtgaaacg
    54601 tcatattgct cataccagct tgggtattca ccatgtacct gatggtaata ggcttctaag
    54661 tcaggattgt cgtcaacctg ctcaaaacgt ctgccgcgct tttcaatgcg ctctagcatc
    54721 ttctcaaagg agacatcaat ataaatcagc agatcaggcc gtttttaagg cattccttca
    54781 agctcctcta gcatattggc taagagctct tggtaaattt caagctctgt cttggtaaca
    54841 tttccatttt tatagttaag tgtcaagaag aactcatctt caaagattga gcggtcaaga
    54901 atattattgt ctgcctggta ggcttcttta atagatttga agcgcttgtt caaaaagaaa
    54961 atttgtagta aaaaggcata ttttttaggg tcttggtaat acagatcaag aacaggattg
    55021 ttatcaacag cctcgtaaaa tacctctgtt cctaaatgct cacccagtgc agcagcaagg
    55081 gaactcttgc ctgcgccgat tgttccagct aatacaatca acatgtttct ccttctatgt
    55141 agtcttagtg tatttgtgca aaaatcgttt caacctcagc taaggtttta gcgcgtgaaa
    55201 cggcactgcg aattttggca gcgcctgctg tccctcgcag gtaatgaggg gctaacccac
    55261 gaaattcacg aacagcaata gcttctccct tgagcctgat gaggcgcttg agatggtctt
    55321 tagcaatatc tagcttttta gcaaagggca gctctggcaa aacctctcct gtctcaaaga
    55381 agtgattaat ttgggtgaag agataagggt tgttcatagc tgcacggcca atcatgaccg
    55441 catctacacc aatctcctca atcatgaacc tagcgtcctg aacagttctg acatctccat
    55501 ttccaataaa tggaatcctg gtaatagctc ttgagacgcg tgcaagggtt tcatggtcac
    55561 aggtgccagt atacatctgc tcacgagtac ggccatgcat ggcaagagct gacacaccag
    55621 cagcttcagc agccaaggca ttctcaacag ctagtgagct gtctgcccag ccggtacgca
    55681 ttttgacagt cagtggaatg tctaaaacag aggttacctc ctgaatgata tggtaaatct
    55741 tatcaggatc gcgaagccac ttggcacctg cttcattttt aaccaccttg ttaacaggac
    55801 agcccatatt gatgtcaaca atgtcagcct tggtatggct ctggataaaa tcagccgcac
    55861 gctttagtcc ttcagcgtca ccgccaaata gttggattga catggggtgc tcattgtcat
    55921 caatatgaag catatgcagg gttttttcgt tattatagag aagtcccttt tcagaaatca
    55981 tttccatgac aacaaggcct gcaccaaatt ccttggcaat cgtgcgaaag gccgaattgg
    56041 tcacaccagc cataggtgca agcactgtac ggtgagggat ttccacatga ccaatcctaa
    56101 agggtgagtt aagccttgtc attgatcagc acctccaaat cagtttggtc aaattggtac
    56161 ttggtgccac aaaattggca aacaatttca gcccccttat cctcgtttag cattgtcaac
    56221 aggtcagctt tagggaggct cattagggct gacgcaaagc gctctcttga gcagtcacac
    56281 tgaaagctca gctgctcttc agctaatcgc ttgtaaggct cttcaccata aatagctgct
    56341 aacagagcgt ctatatgatt ttccgacgct agaagggttg aaatcgcagg catttcctga
    56401 atgcgcttct catagtggct aatctcttcg acagaagctc caggcagcac ctgcagcata
    56461 aagccgccag caaccttgac cttgtcctct tgatctagaa gcacattaag gccgacagca
    56521 gatggtgtct gctcagactc tgtcaagtag taggccagat cctcaccaat ctcaccggta
    56581 atcaagggtg ttgtagaggt gtagggattg cctgttccat agtccgtaat tgtcacaaag
    56641 tgtccctgtc ccataaaagg accaaccagt acttctccag ttgctgtttt tttgatatca
    56701 acaccgggat tttgaatata gcccttgaca tgcccttttg tgtcagcaac agaaataata
    56761 tgcccaaagg aggaatcgcc aataaccttg acagtaacct tactatctcc tttttggttg
    56821 gcagctagaa tctgattggc aatcaaggta cgaccaagtg caaccgttga agatgataag
    56881 gtatgatgcc tttcctgagc atatcgaaca gtttcggtgc aatccaaaac ataggccctg
    56941 aaggcaccgg aggcagaaat tgttttaatt agtttatcca taatttctat tatagcataa
    57001 tgaacaaggc ttgtgctggt tgctttagag gaaagctgct tgaaaataga gaaacactat
    57061 ttggttaata atagcagctc tataaagcca cttaaaaaca gagcagtgct aacaaatggt
    57121 agtattcttg tccttagcac gcagtaagct aatcacctaa gtcagtacaa tcaaacaagc
    57181 atcaaaaaac agctccgata ggttgattaa aggaagaaat gataaaagag ttatttcgta
    57241 atgctttgct gataatgagc aaggtaatca tgtggtgtcg tatcagtgta ctttttgaag
    57301 gttttcaaaa aatgggtggt atcgtagaaa taaaggagct tagccacttc tccagctggt
    57361 actcctcttc gtaaaagtag cttggcttct tgtacttttt ccttcaaaat ataggtctgc
    57421 aacgaaatag aagaatacat tttaaaaaca gctcgtaaat gtgactctga gatataaaga
    57481 tgcttagcaa tatctgatac ctttaatttt gaataaaggt gcttatcgac gtaatataaa
    57541 atactattat aaatttgctg cttatcagaa acacttttgt tagtcaatga ttctgagagg
    57601 ctaataatag cagctgctct tatttgaagc accttaagga gatctgtagc tttttcagtt
    57661 aggttcataa aatgcttaat gcgctcgtag tttttggcaa catcagtatt ttcagtaaag
    57721 cttagttcaa gcagcttaat aaaataaata atagaaagat ttttttcagc tcttaatgcg
    57781 ggaatagaag aggagacgac atctgatgaa gggatacaat tgatttcgtg ctttaatagc
    57841 tctgtattac ccagcttgac taaatcaata atatgattca aataatttaa gacagctggc
    57901 acatgaaatg acggggtatt ttccaattcg agattagcta taatatgagg atcctcccag
    57961 attagctggg cttcctccag taaatcatta atgctttgct ggcagctcat ttcaaagttg
    58021 gtgtcaaaaa aggcatcaac agctatcaaa aggcttcgaa tatgagaagc aggaaaatga
    58081 ggaatggtag agatatagcc aactagctct ttttttgact tatcaggata gcgcttcaag
    58141 aagctatcgg ctaattcctc cttatagcta tcctgaaaga aagaggtgta aaaaggccca
    58201 atgaaaataa acttgtcacc aataggaaac attagagagg attcctcaag cgttccctca
    58261 taacaagtga gctcagtatt actaggaata tctaatgttt taattaattc atagtagggg
    58321 aatcgacgct cctcgtcatc ataagcctga aggagctcaa gattttgaga aagcactaaa
    58381 acaggtaatt gtgataggtt atgcaa
//
LOCUS       DARYMD010000005        56683 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYMD010000005 DARYMD010000000
VERSION     DARYMD010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56683
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(140..505)
                     /gene="rplL"
                     /locus_tag="TU818_000263"
     CDS             complement(140..505)
                     /gene="rplL"
                     /locus_tag="TU818_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL0923125.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            complement(570..1070)
                     /locus_tag="TU818_000264"
     CDS             complement(570..1070)
                     /locus_tag="TU818_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL0923126.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     misc_feature    complement(1099..1234)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(1366..2007)
                     /locus_tag="TU818_000265"
     CDS             complement(1366..2007)
                     /locus_tag="TU818_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL0923127.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MCKKSILHNYNILLTYLTNPFVRELKLASFSASRAGLKHFTDVKMLFHITQLIFSLLM
                     LPTIIYFYQSIKKGRVMLLRRGLIAAALLPIVIACFALMIGFDQFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQVAYH"
     gene            complement(2004..2771)
                     /locus_tag="TU818_000266"
     CDS             complement(2004..2771)
                     /locus_tag="TU818_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL0923128.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            complement(2771..3523)
                     /locus_tag="TU818_000267"
     CDS             complement(2771..3523)
                     /locus_tag="TU818_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL0923129.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLMVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPQTRKAAAIPDDLVVPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGYEFLLHHRPCHLTLTYIKEVRPSTQITSGYHLEH
                     LTSYHEIRSSGQLNAQAIIKWQPITTKESETN"
     gene            complement(3534..4664)
                     /locus_tag="TU818_000268"
     CDS             complement(3534..4664)
                     /locus_tag="TU818_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL0923130.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQISSLKTLYIGGGTPTAITANQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTMQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQNQGLLVEDKDFIRMTKKGLFLGDSVAEKFILD"
     gene            complement(4731..5417)
                     /locus_tag="TU818_000269"
     CDS             complement(4731..5417)
                     /locus_tag="TU818_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0923131.1"
                     /translation="MLSSSIRIGGNMIKHRVDRIASQLDELTQKLYLTMIPEYQEGYA
                     NYIYQTDQPDVQRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECY
                     SMTADPEDYQSILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQE
                     DGVSFLGSIEAFASTTYPQETYVLNVASFNKGAQSLYQKMGYQPTSSFEQYANGSSHS
                     FVRMEKKKQP"
     gene            complement(5451..6803)
                     /locus_tag="TU818_000270"
     CDS             complement(5451..6803)
                     /locus_tag="TU818_000270"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL0923132.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            complement(6856..7812)
                     /locus_tag="TU818_000271"
     CDS             complement(6856..7812)
                     /locus_tag="TU818_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL0923133.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTIKK"
     gene            complement(7809..8660)
                     /locus_tag="TU818_000272"
     CDS             complement(7809..8660)
                     /locus_tag="TU818_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL0923134.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            8762..10105
                     /locus_tag="TU818_000273"
     CDS             8762..10105
                     /locus_tag="TU818_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL0923135.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILDTL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMMTGITSAFLSAKRKKT
                     GKPIAVLEIDEASLARVTTYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKDLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLNCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            10105..10893
                     /locus_tag="TU818_000274"
     CDS             10105..10893
                     /locus_tag="TU818_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL0923136.1"
                     /translation="MTYTSLQSPENRDYQYDLHIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGAKVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGGIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSTVSLAAYDKILQHETSEEYADVKSKASFDS"
     gene            complement(11517..12506)
                     /locus_tag="TU818_000275"
     CDS             complement(11517..12506)
                     /locus_tag="TU818_000275"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL0923137.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIEQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTTEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILVKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(12748..14517)
                     /gene="lpdA"
                     /locus_tag="TU818_000276"
     CDS             complement(12748..14517)
                     /gene="lpdA"
                     /locus_tag="TU818_000276"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL0923138.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKIIRQAGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPDQGSAPSAPKAELAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGVQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILSKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     MHGSTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(14726..16135)
                     /locus_tag="TU818_000277"
     CDS             complement(14726..16135)
                     /locus_tag="TU818_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL0923139.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAAGESVDNSTASSEKTTEIPVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMSLSEFVLASKDVIKKAQGGKLKATEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(16259..17257)
                     /locus_tag="TU818_000278"
     CDS             complement(16259..17257)
                     /locus_tag="TU818_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL0923140.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(17337..18305)
                     /locus_tag="TU818_000279"
     CDS             complement(17337..18305)
                     /locus_tag="TU818_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL0923141.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(18811..20721)
                     /locus_tag="TU818_000280"
     CDS             complement(18811..20721)
                     /locus_tag="TU818_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL0923142.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVSRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRVDEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLVNYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIHLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLTKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEREELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(21131..21916)
                     /locus_tag="TU818_000281"
     CDS             complement(21131..21916)
                     /locus_tag="TU818_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL0923143.1"
                     /translation="MASISIEYHSEILAMERHVKVIYPDQSELSPEEQGYQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     IGELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(22022..23683)
                     /locus_tag="TU818_000282"
     CDS             complement(22022..23683)
                     /locus_tag="TU818_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL0923144.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGILPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(23893..24651)
                     /locus_tag="TU818_000283"
     CDS             complement(23893..24651)
                     /locus_tag="TU818_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923145.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLLLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRVGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(24648..25517)
                     /locus_tag="TU818_000284"
     CDS             complement(24648..25517)
                     /locus_tag="TU818_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923146.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGFATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDIKRIQDYLPFAADTNVLVAGLVVATLVIFLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRMELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISVVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(25531..26526)
                     /locus_tag="TU818_000285"
     CDS             complement(25531..26526)
                     /locus_tag="TU818_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0923147.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVIVASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVEVVDDGKPFLNLKAARDLGLMISKDLLKRSDLTGKQ"
     gene            26878..28548
                     /locus_tag="TU818_000286"
     CDS             26878..28548
                     /locus_tag="TU818_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL0923148.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     AYIEPPKTTAVNPFTISDIALFEVLQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(28637..29875)
                     /locus_tag="TU818_000287"
     CDS             complement(28637..29875)
                     /locus_tag="TU818_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL0923149.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNVIEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALAIEYDDETVFELATILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDPQLLLLASQ
                     LAFELHDPAGSERYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(29865..31046)
                     /locus_tag="TU818_000288"
     CDS             complement(29865..31046)
                     /locus_tag="TU818_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL0923150.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSGHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(31109..31585)
                     /locus_tag="TU818_000289"
     CDS             complement(31109..31585)
                     /locus_tag="TU818_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL0923151.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(31763..32809)
                     /gene="rfbB"
                     /locus_tag="TU818_000290"
     CDS             complement(31763..32809)
                     /gene="rfbB"
                     /locus_tag="TU818_000290"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL0923152.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHVTVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTADTNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(33001..33597)
                     /locus_tag="TU818_000291"
     CDS             complement(33001..33597)
                     /locus_tag="TU818_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL0923153.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKQKYAFVNYA
                     DPSLGIAWESLEQAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(33597..34466)
                     /gene="rfbA"
                     /locus_tag="TU818_000292"
     CDS             complement(33597..34466)
                     /gene="rfbA"
                     /locus_tag="TU818_000292"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL0923154.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(34523..35632)
                     /locus_tag="TU818_000293"
     CDS             complement(34523..35632)
                     /locus_tag="TU818_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL0923155.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNEDKLE
                     ELYQLAIRRKQESPLIGDLAIRCRSDIRVDFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVGISIEKQGYLVDGMVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLIDYHIANVTTDNYAVVMPEGELDIIPFEHDRLSVGASHENDKGYDLEPDVAVLEAL
                     EQEALTYYPKLSSASDVSYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTLGP
                     LIAQQLIALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(35687..36475)
                     /locus_tag="TU818_000294"
     CDS             complement(35687..36475)
                     /locus_tag="TU818_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL0923156.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLELVKHDISVYVSHTNID
                     IVSDGLNDWFCELLGIEQTEVLVETQDGYGIGRVGNVAEQSLEELGLTVKEAFGLDVV
                     RLVRYTGQNPLISRVAICGGSGDKFYQAALAKGAQVYITGDIYYHTAQEMLTEGLLAI
                     DPGHHIESLFIDKLLAKMQAWKKEEGWQVTIMASKASTNPFSHL"
     gene            complement(36465..37151)
                     /locus_tag="TU818_000295"
     CDS             complement(36465..37151)
                     /locus_tag="TU818_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL0923157.1"
                     /translation="MESHLSKRLRHVASYVPDGAKLLDVGSDHAYLPIFLVETEHIQE
                     AIAGEVVKGPFVSALKNVSQYGLTEHIEVRLANGLAAFEARDAVDCITICGMGGRLIA
                     DILAAGKEKLQGIERLILQPNNREDELRAWLSANAFCISAETIMTENGKYYEIIVAEP
                     GQQSLTDQEQRFGPFLSQERSSVFVAKWQKERDKLVYALSCVPATKPVERASISQKIK
                     AIEEVISHES"
     gene            complement(37225..37887)
                     /gene="nth"
                     /locus_tag="TU818_000296"
     CDS             complement(37225..37887)
                     /gene="nth"
                     /locus_tag="TU818_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL0923158.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLITVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLT
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEIYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDTCPVQSYCSYYKTTYGKK
                     KV"
     gene            complement(37887..38564)
                     /locus_tag="TU818_000297"
     CDS             complement(37887..38564)
                     /locus_tag="TU818_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL0923159.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELAPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKGEHEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTIHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(38631..39149)
                     /locus_tag="TU818_000298"
     CDS             complement(38631..39149)
                     /locus_tag="TU818_000298"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL0923160.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(39229..39597)
                     /locus_tag="TU818_000299"
     CDS             complement(39229..39597)
                     /locus_tag="TU818_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923161.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSLYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(39606..41816)
                     /gene="recJ"
                     /locus_tag="TU818_000300"
     CDS             complement(39606..41816)
                     /gene="recJ"
                     /locus_tag="TU818_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL0923162.1"
                     /translation="MITSKYQWTIADKEPDAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMEKAVHRIRQAIEGLERILVYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAVAFAQ
                     AQGVDVIVTDHHSLPAELPDAFAIIHPEHPAAAYPFQKLAGCGVAFKLASALLETIPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     ISFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISSKNEERKVLVQEIFAQA
                     MAMLDLDKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLPSDRLEELSELLCQYVAAKGHDGQEKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAVEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKVVVIDEVPDDIDALKGLFRHREFEAIYFKNHIKRPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(41813..42577)
                     /locus_tag="TU818_000301"
     CDS             complement(41813..42577)
                     /locus_tag="TU818_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL0923163.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLDSLYQ
                     ARGNKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAM
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERQVYVTTVNPGPIATSFFEQADPSGQYLASVAGFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(42577..43506)
                     /locus_tag="TU818_000302"
     CDS             complement(42577..43506)
                     /locus_tag="TU818_000302"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL0923164.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(43521..44159)
                     /locus_tag="TU818_000303"
     CDS             complement(43521..44159)
                     /locus_tag="TU818_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL0923165.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEMYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGEPEDITP
                     EHALLTTIYRFSNEMTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(44152..45390)
                     /gene="hflX"
                     /locus_tag="TU818_000304"
     CDS             complement(44152..45390)
                     /gene="hflX"
                     /locus_tag="TU818_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL0923166.1"
                     /translation="MIETKARQERVILLSVVLQAADHAELSMTELASLAKTAGAEVVD
                     CYLQKRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEDALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(45475..46365)
                     /gene="miaA"
                     /locus_tag="TU818_000305"
     CDS             complement(45475..46365)
                     /gene="miaA"
                     /locus_tag="TU818_000305"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL0923167.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            46498..46674
                     /locus_tag="TU818_000306"
     CDS             46498..46674
                     /locus_tag="TU818_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL0923168.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(46830..47467)
                     /locus_tag="TU818_000307"
                     /pseudo
     CDS             complement(46830..47467)
                     /locus_tag="TU818_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            complement(47624..49888)
                     /gene="glgP"
                     /locus_tag="TU818_000308"
     CDS             complement(47624..49888)
                     /gene="glgP"
                     /locus_tag="TU818_000308"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL0923169.1"
                     /translation="MKRFTDYTEMTLGKSLASASNEEIYLSLLSYLKEEASKKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEALERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMDGYTNHTILAEALEKWPLDFLNEVVPQ
                     LVTIIEQLDALVRARVSDPAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(49914..51416)
                     /gene="malQ"
                     /locus_tag="TU818_000309"
     CDS             complement(49914..51416)
                     /gene="malQ"
                     /locus_tag="TU818_000309"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL0923170.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKTYANQNGITIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFKAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHNYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAAAESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLEDDIKAEHKAYLIHLTELYGRANNHH"
     gene            complement(51623..52645)
                     /locus_tag="TU818_000310"
     CDS             complement(51623..52645)
                     /locus_tag="TU818_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0923171.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDMEAEVASERYIGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            52892..54145
                     /locus_tag="TU818_000311"
     CDS             52892..54145
                     /locus_tag="TU818_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0923172.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDTKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            54445..55806
                     /locus_tag="TU818_000312"
     CDS             54445..55806
                     /locus_tag="TU818_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0923173.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIHHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            55806..56642
                     /locus_tag="TU818_000313"
     CDS             55806..56642
                     /locus_tag="TU818_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0923174.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSRYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
BASE COUNT        16457 a        13418 c        10673 g        16135 t
ORIGIN      
        1 aaaataaaaa ccctgccaaa aaatctttgg tagggttttt agcaggaaac caaatcaatt
       61 tatcagtttc tctaaatcgc tctaagcaat cattaaacct tgatttacta ggcttccgca
      121 atcaaattgc gatactctat tatttaagag tgatagttgc tccagcttct tcaagcttag
      181 ctttgatttc ttctgcttct gctgctgcaa caccttcttt gatgttagca ggtgcgccgt
      241 caacaagacc tttagcttct ttaagtccaa gacctgtgat ttcacgaact gccttgataa
      301 caccaacttt tttgtcacca gcagatgtca actcaacgtc aaatgaatcc ttagtagctt
      361 cttcagcacc accagcagca gctacagcta caggagcagc tgcagtcaca ccgaattctt
      421 cttcgatagc ttttacaaga tcgttaagct caaggattga agcttcttta atttcagcaa
      481 taatgttttc aatgtttaat gccattgtca tttcctccaa atagttatat taaataatga
      541 tttgtagctc taggctacct ctaaaggcct tacgcagcgc cttctttgct ttctgcaaca
      601 gccttgacag cgtatgcaac gttgcggact ggagcttgaa gtacagaaag aagcatagaa
      661 agcattcctt cgcggtttgg caatgctgca agtgcttgaa tttcctcttt tgaagaaaca
      721 acaccttcga tagcaccacc tttaatctca agtgcttcag cagttttagc aaagtcgttg
      781 atgactttag ctggtgcgat aacatcttca tttgaaaatg ctactgcaga tggtcctacg
      841 aatatatctt ttagctcgtc aagacctgct ttttcagctg cacgagtcaa gattgagttt
      901 ttgataacct tgaactcaac gccactttca cgaagtgaac gacgaagaac agtatcttga
      961 tcaactgtaa gaccacgtga atctacaaca acgatactta cagctgcttt cattttctca
     1021 gcgataagct caacttgttc agctttttta gcgataattg cttcactcat tagttttacc
     1081 tccgttttta tttttgggct aggcacaaaa aaatcgcacc taaacctaga cacgaaagta
     1141 caaatacgtt atcttcaata atgacgtttt gtgcctcggc aggaatatta tgagcacgct
     1201 cccctgctgt cttaggtcag ttttattcaa aaccatagtt agtatagcct ttttaaatga
     1261 ctttgtcaac ctatttttta gaaaatctta aataaaaaag gaaagctctt ggctttccgc
     1321 taaatagatc tgattagtgg ctcaaaagcg cctcctaact taagcctaat gataagcaac
     1381 ttgtgacgat tgattgctat aacttagccc gatcaagctc cacagtatca tctcataaat
     1441 aaagaagaac aaggcaaagc aatgcccaaa aaaggcctct ggcaaaatcc aaatgacagg
     1501 atctgtcagc ggatcaaaca accagcttga atctcctaca aagagaattt gatgaaaaag
     1561 ggtaaagaac tgatcaaagc caatcattaa agcaaagcaa gcaatcacaa ttggcaataa
     1621 ggctgctgct attagccctc ttcgaagcag cataaccctt ccttttttga tgctctgata
     1681 aaaatagata atggttggca acataagcag gctaaagatc agctgtgtta tatgaaacag
     1741 cattttcaca tctgtaaaat gctttagacc agctcttgat gctgaaaagc tggctagctt
     1801 tagctcacga acaaaaggat tggttaagta agtcagcaat atattatagt tgtggagaat
     1861 agactttttg cacatcaaaa ctgcctgctc tagttgcaaa taatcaacct caatcggata
     1921 aagcagccaa gataaataga tagttatcaa aactgccagt gctagtagcc aaagccaact
     1981 ggcaatgaac ttgccttttt caatcataat agctcccact catctaagct agccaagaca
     2041 tgatcaggct taattggaag gcttggaacc tcttttgcct ttgtaaagcc ggttgttact
     2101 agaatagttg ccatatcatt ttgaattcct gccatgatat ctgtcaggta attgtctcca
     2161 accatagcca cctcagaacg tggtaccttt aagatctcta gggctttatt catgataatc
     2221 gcatttggct ttcctataaa tactggcttc actctagttg ctgcctcaag gagcgcattt
     2281 aaagcgccag cacctggcat tagcccacgc tctgttggaa tatttaagtc aggattggtc
     2341 ccaataaaca aggctccttt ttgaatggca agtgttgcaa ttgataacat ttcataggta
     2401 acctcagtat ctaagccaac aacaacatag gctggatttt ctgtatcctc ggtatagcct
     2461 gcctctgcaa tggcagactt taagccagtc tcgccaatca cataggctgt tttgcctcga
     2521 ttcatatcat tcatgtaatc aacggttgcc attgtagcgg tgtaaatggt ttcaagacct
     2581 gtatgaacgt taaattgatt ggctagcatt tcctgaacca tttcaggtgt tcttgtggtg
     2641 ttgttggtaa ctaagagata agggatacct ttttcctgta aacgcttgat aaagcgctca
     2701 ccagccggga tacgattttt cccttgatag atggttccat ctaaatcaat taaataagct
     2761 ttatagggca ctaatttgtc tcactttctt tagtcgttat aggctgccat ttgataatgg
     2821 cctgcgcatt aagctggcct gatgacctga tctcatggta ggaggtcaaa tgctctagat
     2881 gatagcctga ggttatttga gtgctgggcc tcacctcttt gatataggtc aaggtaaggt
     2941 ggcaaggtct gtggtgtaat aaaaattcat atcccaaaac gtcatacatc caatccaaat
     3001 acttactatt attggcatga ccattcatat caatgtcaaa ataacgaacc tgataagctt
     3061 gaaccatagg atcctgaagc tcatctattt tgataggacg cttgattttc ttaacaaagt
     3121 cagcctgata aggcaccacc aaatcatctg gtatcgcagc tgccttacgt gtttgaggat
     3181 ttagcagggc aaaatgagat aaaatggtca tgatggcatg acctgcctga tcataaatgt
     3241 gaaattgccg gtaacaaaat aatttattgt aagaaatagc ttgcgtttca atggttactg
     3301 tttccccaaa ccttggcata cgatcaatcg ttacatcata atccgtaaca acccaaatca
     3361 agccatattg ctgaagtaac acctcattgc ctcgtccaat ttcagctgat tgtcttgctg
     3421 ataccattaa gcaatgtgct aataaaaggg gcagcttgac atcagcctta acatcacaaa
     3481 aatcaaaaga cagcttaagg ctttcgctat accttaatcc cataacacac ctcctaatct
     3541 aagatgaatt tttcagcgac agaatcacct aaaaagaggc cttttttggt cattctgata
     3601 aagtccttgt cctctaccaa aagcccctga ttctgaagct ctctcacaac aggaccatag
     3661 cgtgactcaa atgataggcc aaatttttct tgaaaccgac tgactgatac tcctgatttt
     3721 tttcgcagac caagaaaaag ctcctcctcc atcatctcct ccttggtgag cacttcctca
     3781 cttaacctag catttccatc tgctactgcc tttaggtaat gctgaatagg aacccggttg
     3841 cggtaacgaa tcccatcaag atagccagaa gcccctgcgc cacagccaaa atactcatca
     3901 ttattccaat acatcagatt gtgcctgctt tcaaagccag gcttagtaaa attagaaatt
     3961 tcgtaatgct caaagccact ggcttccatt tcagaaataa tatactcaaa catctcagct
     4021 tccaaatcct cagtgggcaa atggagcttg ccacgacgca ttttgttcat aaaaacagtg
     4081 tgatgctcta ggataaggct atacaggcta aggtgaggaa tatctaaagc aagtgcctta
     4141 gccacatttt ccttgacctg ctgcatggtc tgtccaggca aagcataaat gagatcgata
     4201 gacatatttt gaaagcctgc ctccttaaga ctagcaatgg tcgtataaat ctgagcctca
     4261 gtatgactgc gtccaatctg ctttaattgc ttgtcattaa aagtttgaac gcctagggaa
     4321 atccgattga cagccgattg ccttaatact gcaatcttat cctcagtcaa atcacctgga
     4381 ttggcctcga tggtaaattc ttcaagctgg tctagctgta ggtgctgctg caaatggctc
     4441 agcaaataat caagctgatt ggctgttatg gctgttggtg ttccaccgcc aatataaagt
     4501 gtcttcaagg agctgatctg ataggattca aattccttaa tcagtgcctc taggtaggca
     4561 tcgacaggct gatttttgat aaatacctta gaaaaatcac aatagtagca aatttgtgtg
     4621 caaaaaggaa tatgcacata ggctgaggtt ggtttttttg acatggtaat attatatcat
     4681 tttagctcag aaattcatgc caagtgatta gctttttgac atgtactaac ctaaggctgc
     4741 ttctttttct ccattctcac aaaggaatga ctactcccat tagcatactg ctcaaagctt
     4801 gaggttggct gatagcccat tttttggtag aggctttgtg cgcctttatt aaagctagcg
     4861 acatttaaaa cataggtttc ttgcggataa gtagtgctag caaaggcttc aatgctgccc
     4921 aaaaaagaaa caccatcttc ctgaccagta gtatcagggg ccataccaag accaatctca
     4981 agctctgatt cctgttcaaa aaagctggca aagccaaaaa gaacaccatt gcgaagcact
     5041 tgaaagtaat gctctccacg cgccttgggt gacaatattg actgatagtc ctcaggatca
     5101 gcagtcatgc tatagcactc ataagctggg ctatagatcc agtcatgcgc aatgatttca
     5161 gcactatgct gtgtcatcgg catcaggtaa aaagaagact cagacaataa gcgatgaaag
     5221 gtcttgttga tatgctttat gcgacgccgc tgcacatcag gctgatctgt ttgataaatg
     5281 taattagcat agccctcctg atattctgga atcattgtca aatacagctt ttgggtcaac
     5341 tcatcaagct gactagcaat cctatccact ctatgcttta tcatattacc tccaattcta
     5401 atgctgcttg atagcataaa aagtgccgaa gcaacgacac tttttctaga ttaatcaagg
     5461 ccaatttccg cacgaacaac cgctgcaatg gtatcaacat aatagtcaac ttcttcattg
     5521 cttggtgcct ctgccatcac acgcaacaat ggctctgtgc cgctaggcct taccaaaatg
     5581 cgaccattac cagccatttc tccttccatc tgagcaataa cctcagcaat agcaggcact
     5641 tccatagcac gctccttcat gctgttgtca acacgaatat taacaagctt ttgtgggtaa
     5701 atagtgacct cactggccaa ttcggagaga gttttacctg tctccttcat gattttggtg
     5761 agctgaacag ctgtcagttg accatcacca gttgtattgt aatccatgat aatgacatgc
     5821 cctgattgct caccaccaag attgtagccg aactgacgca tctcctcaac aacgtaacga
     5881 tcaccaacag ctgttacctt cttatgaatg ccacagctat ctaatgcctt gtgaaaacca
     5941 aggttagaca tcactgttgt cacaatcgta tttttagcta gcaagccctt ctcagaaaga
     6001 tacttgccta tgataaacat gatcttgtcg ccatcaacaa tagcaccatt ttcatcaaca
     6061 gcaattaaac gatcactatc gccatcaaaa gccaatccaa tatcagaggc tgtttctgtc
     6121 accaagtcct gaagcttttc agggtgtgta gagccgatac catcattaat gtttaatcca
     6181 tttggattct caccaataac tgtaatgtct gcatttaaat ctaaaaagac attacgagct
     6241 gaaacagaag ctgcaccgtt agcagtatca agagctatct ttaaaccgtc taaatctgct
     6301 ccagtagtaa ccaagaatct ctcgtacttg cgcaagcctt ctggataatc aaccaaggct
     6361 cctaagccct ccgcacttgg acgtggtagg aggtcctctt tggcatctaa gagcgcttcg
     6421 atttctagct cttgctcatc agccaattta aagccatcac tcccaaaaaa cttaatgcca
     6481 ttgtcaagag caggattgtg actagctgaa atcatgacac cagcactagc cttttctgta
     6541 cggaccaaat aggacacacc aggagttgca agaacaccaa gcttatagac ctctatccca
     6601 acagaaagca agccagcaat cagggctgcc tctagcattt caccagagat acgggtgtca
     6661 cgagcgacaa aaactctagg cctttcagtc tcatgctgac ttagcacata accaccgaac
     6721 cgaccaagct taaaagcaag ctctggggtc aactctacat tagcctcgcc tcgaacacca
     6781 tccgttccaa aatattttcc cataatttat atcagctaaa cgcttcctcc attccatttt
     6841 cctagctatt atgctttatt ttttaattgt tgtcaactga acggttacta ccgaaggctc
     6901 tatagaaacc tgatttgaaa ccaagctgac cgttttgctc gtgtttttgg tgacgtcaga
     6961 aatattgacc tctgccacca cctcatcaat agtttcaagg acctcccgac taccagaaat
     7021 aacagcggtc tgcttggaga gcttatactg gatatctgac agactgtcat ccattagtcc
     7081 aactgcctcg actcgaatag gaactgattt ggtgattttt ttgacagaaa ctgacaaatt
     7141 agccttggct ggatcgatcg cactagctaa aatggtacca tcggcagcta ctgcctgcag
     7201 ggttactcgg ctgctataat tagcatctag cacctgatca tcaggtaatt tagcgacaac
     7261 atgatctatc aaggcaatag tagactcatc acttgtgacc tcaaccttgt caatacctgt
     7321 ttcaattttg ctaatctcat agcccttagc cagctgctta ctatcgacgc tgccacgcac
     7381 cggaaaggtc tttgttttct tatttccaat cgttaccgaa atcttatcag gagaaacagt
     7441 tgctgtcaca ccagtaggta gattgataac ctttagggtc accgttgcag tacctggctt
     7501 actctttgtt agatcagcta cgatcttaaa gcttctagtg tcactgttta cctctgaatc
     7561 cagctttatg cggttggtag aggtcagata aacctctgca ccgtaagaat agccgctgat
     7621 gaagtactga tcactatcat acttgatatc aataggaacg tcctttaagc tatgggtgta
     7681 ggtttcaata gggctataaa tttgagaatt agaatgatta tgactgctag aagcagcggt
     7741 caaaaaaaga ataatcgcaa aaaagattga cactaagccc agcccaagac gactatttaa
     7801 aaacctcttc atttagcttt gcctcctaag atttttttat accaaggtaa tgtcgcaccg
     7861 ggctcattca tcaaatgagt cttgagaacc gcctcaagct cttctgttga aaggtcgtgt
     7921 aaaaattgac ccttacgagc gatagagaca gctcctgtct cctcagaaac aattatcgtt
     7981 acagcatcag aattttctga aagtccaatt gctgctctgt gacgtgttcc aaattctttg
     8041 gaaatcgaca ttgattcaga caaggggaga taagcacagg ctgcagcaat tttattgtta
     8101 gccacaatga ccgcaccatc atgcagcggt gtgtttggga taaagatatt gatcaatagc
     8161 tgactagaaa tatcagcatt taggggaatt cctgttgcga tatattcctg caaggtctgc
     8221 gtttgctcaa tagcaatcag agcaccaatc ttccgcggtc ccatataagc aactgatttt
     8281 aagagcgcat caaccagcat ctcctcatca ctcaagcttt gcttttgcaa aaatacctgt
     8341 gttgatcggc caaatttttc aagccccgct cgaatttccg gagcaaaaat caccacacct
     8401 gcaatcactc cataggtgat gacctgattc atcagatagg ttatagtcgt aaaccctatc
     8461 cactcggcaa tcacacgaat gatgataaag aatataaccc cttgtaccaa ggacatgatc
     8521 ttagttcctg ccaaggattt aataaaacgg taaatcaaat aggctactat taaaatatcc
     8581 agcaaatgaa ccaccaacat caaggggtca tcaatcaggc ttagtaaaaa ttttgtgtca
     8641 atacttgata aattactcat acaattctca tttctatgtc agatagatac ctctaacatt
     8701 atatcacgtt tcaagatgtt ttccctatct aaaatttaag aacttatgtt aaaatattaa
     8761 catgaaacta aagacactac tcgctatagc agccggaagg actgcgcagc tcattttaaa
     8821 taaaatcgga agaggctcaa cctaccccgg acgattggcc ttgatgtggg ataaggatat
     8881 tttagacaca cttgccaagg actatgagat tgttgttgtg acagggacaa atgggaaaac
     8941 cttaaccaca gctctaactg ttggtatcct aaaagaagcc tttggtgagg ttttgactaa
     9001 tccaagtggc gccaacatga tgacagggat tacctctgcc tttttatctg ctaaaagaaa
     9061 aaaaacaggc aagcctattg ccgtcttaga gattgatgag gcaagccttg caagggtaac
     9121 aacatacatt aagccaagtc tttttgttta cactaatatc tttcgagacc agatggatcg
     9181 ctacggtgag atttacacca cctatcagat gattgttgat ggtgctagtc aagcgccgaa
     9241 ggcaaccatt ctagctaacg gtgatagccc tatctttgcc tcaaaggacc tggttaatcc
     9301 tgttaaatat tatggctttg acacacctaa gcatgagcca cgcctagctc actacaacac
     9361 tgaaggcatt ttgtgcccaa aatgtgaaca gattctccgt tatcgtctca acacctatgc
     9421 taatctagga gactatacct gcttaaattg tgatttccaa aggcctaagt tggattacaa
     9481 gctaacgcaa ttaaccagca ttacccatca tagctcagcc tttgtgattg acgatcagac
     9541 ttatcgcata aatgttggag gactctataa catctataat gccctcgcag ctgttgctgt
     9601 tgctgagttt tttggcattt ctgctgatca gattaaggct ggcttcaata aaagcaaggc
     9661 tgtttttggt cgtcaggaaa ccttctccat caacggtaaa gcctgtacgc tggttctcat
     9721 taaaaaccct gtgggtgcta gtcaggcact agaaatgctg cgcctagccg attatccctt
     9781 tagcctatct gtgcttttaa atgctgatta tgctgacggt attgacacaa gctggatttg
     9841 ggatgctgat tttgaattga ttaatcaaat ggacattact gagatcaacg ccggtggggt
     9901 tcggcattct gaaattgcaa gacgcttacg agtgacaggc tttgatgagg ctaaaatcac
     9961 atcattcgat aagcttgaag gtatcatgca agccattgaa aaccaagagg ctgagcatgc
    10021 ctatatccta gcgacctata ctgctatgct agcatttcgt gagctgcttg ccagccgcca
    10081 cattgtcgaa aaggagatga tctaatgacc tatacctcgc tacaatctcc ggaaaatcgc
    10141 gattatcaat acgaccttca tattgctcac ctttatggta atttgatgaa tacctatggc
    10201 gataacggca atgtcttgat gttgaagtat gtcgctgaaa agctaggcgc taaggttaga
    10261 gttgatattg tatccattgg ggataccttt gaccaagatg attatgacat tgttttcttt
    10321 ggtggtggtc aagattatga gcaagccatt gttgctagag atttgccatc aaaaaaagag
    10381 gccttagcag cctatattca ccaaaataag gtactccttg ccatttgtgg tggctttcag
    10441 ctgctgggac agtactatat tcaagccaat ggccttaaaa tcaatggcat tggggttatg
    10501 ggacattata ccttaaacca agataataac cgctttatcg gaggcattaa aattcacaat
    10561 gatgactttg acgaaaccta ctatggcttt gaaaatcatc aaggacggac ctttttatct
    10621 gacgatgaaa agcctcttgg acgtgtcatt tatggaaatg gtaataataa agaggaccaa
    10681 actgagggcg tccactataa aaacgtttac ggcagctact ttcatggacc aatcctttcg
    10741 cgtaatgtca gcctggccta tcgcctagtc acaactgctc tcaaagaaaa atatggctcg
    10801 actgtttcct tagcggccta tgataagatc ttacagcatg agacctcaga ggaatacgct
    10861 gatgttaaaa gcaaggctag ctttgacagt taagtccttc tcatagcctg attaaaccac
    10921 aacagacatg caaaacagtt attcccgaat gaaaatatag atttaaatag acaccctcaa
    10981 tgtttttcct atcataaaat ccataaaaga taagacatat tcttgcaata actgaacatt
    11041 gaaagacaga aagctttctg tccttactaa acatctttca tgcgtctgtc gtgctgatca
    11101 agcgagataa ccccaaaaaa gtgctagcac agtaacaaaa tggctatgac catatgtctg
    11161 tgcagctcta ctgtcactgc atagacaggc tagaggggac gccctacttg gttcagcgat
    11221 ctaggggtag gtctagcttg tttgtgctga gtctgtttcg gtagcaaaga ttgaatcctg
    11281 ctataagata ctctcaaaaa gattaaccca aaagccttgc aacacattta acgtttttag
    11341 ggataagtac cgatatgcag acacatagca ggagatctat gtgtctggta ccaaaggaca
    11401 caaaaaacta aagtaacaca ctaaaagcca catgataccc atttgatagg gggcgtcatg
    11461 tggctttttt ctatctcact gttcattaca aaaagccaaa ccagcttctt tttgcattag
    11521 gcaacaatgg cctttgccac ctcttctact gtcatacgtg agaaatattg tgttgtatca
    11581 atggtttgaa gacgctcaag cacatcagca tactcgtatt tgcaaccaat gagtaggctt
    11641 tcaatatcct gcacgtcctt aataccaaag aaatcaccgt agatcttaag attcttaata
    11701 acagaatttt caacattagc aaaggttgag attttaccgg cagggtagcg aacattacgt
    11761 tcaatcgtgt attcaggtgc ctttccatag gtccaatccc agctcccaaa ttgctcctca
    11821 gccgattgtt gaatcttagc cagctcgtcc tctgacaaga cgtattctgt catgtctgga
    11881 taggtctcct tcattttaac caaaatcttg tctgaaaatg cttctacgct gattttttct
    11941 ggcagctcat ttaaaatatt ggtcacgcgg gctcgtacag atttgactcc tttggactca
    12001 atcttatcct tactgacctt gagcgcatca ccaagaacag tcatatccac atcaaacaag
    12061 agacagccat gatgcatcat acgtccctta taataggctt gagcattgcc acagattttc
    12121 ttgccatcaa tttcaatgtc attgcgacct gtaaaattag ccttaactcc taaatcagcc
    12181 aaggtctcaa taactggctg tgagaaggtt ttaaaatcaa aggctccttc tgttgtttta
    12241 ttggaaataa tcgtgtagtt aaggttattg agatcatggt aaactgcacc accgccagac
    12301 aagcgacgaa ccacatgaat accatgctgt tcgatgtact ccttgttgat ttcctgaatg
    12361 gtattttgat gcttaccaat aataatagcc ggctcattga tccagaggat aaacaattca
    12421 tcctcatcaa ccaattctct aaaggcataa gcctctagag caatgttaaa ggcagggttg
    12481 tggctcttat taacaatgta tttcatttct atctcctata gcgataatcg ttatcatatt
    12541 ctattcttta ttctaatgga aactcttaca aaagacaagc taaaagaggc tagcaaaagc
    12601 aagggaacta gtaaatgctt cctcaatcaa gaaccatctg caagctagca gtaaagcttg
    12661 atctaactta aagagccttc cttgtatcaa cgaaagagct gagaaatctt tttcccagcc
    12721 cttttttatc gcagctatat agctagctta ttttttacgt tttggtgggt tatgaatggc
    12781 ttcgccaagc acatctgcaa aggcttcgta catcacctct gagaaggttg ggtgtccatg
    12841 aattgacaat agcaattcat caactgttag ctcagcctcc atgattgtgg ctgcttcatt
    12901 gatcatttca gcggctgctg gaccaatgat gtgaacacca agtatttcat ggtatttagc
    12961 atctgcaata acctttacaa agccatgagc ctcgtttgac gcaatagcac gaccatttcc
    13021 tgtaaagcta tttttaccaa taagaacatc gccatattgc tcacgagcct gctcttcagt
    13081 taaaccaacc atagcgacct cagggtgagt atagaccgcc gctggagtgt attttaggtt
    13141 agccttacgt gttgtgctgc catgcatggc attctcagca gccacctcac ccatacggta
    13201 agcagcgtgg gcaagcattt tagtgccgtt aacatcaccc ggtgcataaa tgcctgggat
    13261 tgacgtttct tggtagtcat taaccttaat gcggttacgg tccatttcaa ggttgaggtt
    13321 ttcaagacca ttcatctgtg gcacacgtcc aatagatagc aaggcctttt cagcaacaac
    13381 ctcttcgcca ttattaagct tcaaggtcaa ctggttgttg gcttcaacaa tctcagagac
    13441 accaactgag gtctttattg tcatgccttt cttagaaagg attttttgaa gctccagtga
    13501 aacctccttg tccatggcag gaataatgcg gtcagccatt tcaataactg taacctctac
    13561 accgtaagag gcccaaacaa gaccaagctc aataccaaca acaccaccgc ccataacagc
    13621 aagtgatttc ggcatttcac gcaaatcaag aatatcatca gatgtcaaga caagcttaga
    13681 atcaatccct ggaatattga tgcgtgagac cttagagcct gtcgcaagaa taatattgcg
    13741 ccctttaatg gtttgcacac caatggtaac cgttttatca ggatttacct gaccaaggcc
    13801 attaaagatg gttaccttgt tggctttaag aagcccttga accccacctg ttagcgtctt
    13861 aacaaccgta tttttaaagt caactgtctt atccatgtca atagtatagt tggttgaagc
    13921 aaggttaatc ccgcgtcctg ctgcaatctt gatgccatca aggatttcag catttttgag
    13981 gtaggttttt gttgggatac agccaacgtt taagcaggta ccgccaaatt cagatttttc
    14041 aacgatagca atcttgccgc ccagctgagc accacgaata gcagcgtagt aacccgcagg
    14101 accgccaccg acaacaatga tgtcatattc atcagcagca agctctgcct ttggtgctga
    14161 tggcgctgat ccttgatccg gtgcctttgg cacctcaaga ccagccgcct gtaaatcctc
    14221 ggttgtacgc gcaacattga catcagccgc tgctgggctt gatacatcga tagcttcacc
    14281 cgcagctcca atgtagccga taacttcggt tacagggact gtctcacctg cctggcgaat
    14341 gatttttaaa agcacacctg agtcttctgc ttctaattcc atattggtct tgtctgacat
    14401 gatttccaga agaatgtcac cctcgctgac agtgtcaccc tcctgctttt tccactcgat
    14461 gatctcgcct tcttgcatgt caacaccgag ctttggcata ataatttcaa cagccataat
    14521 gatattgtaa ggaacgttca aatgcaatca gatgccttaa caatcagcac tggctaacat
    14581 aagcctgcta aaagccctgc atttagctca tagctagtga ctacgagctc gttccagatc
    14641 ctttctatag ttttaaagaa ttatcttttc gttactttgt ttctgaaata tgctctcttt
    14701 gcatcgcagg ccataaggcc tgtcatcaga ttagcagttc aaatggattt tccatcaatt
    14761 ttttgagatc aaccatgaat ttagcaccat tcatgccgtc caccagacgg tggtcaattg
    14821 tcagacacat tgccatgatt ggacgtgcaa caatctcacc atcgaccact gttggggttg
    14881 gaatggttgc cccaatacct agaatagctg aattaggctg attgataatt ggattgaagg
    14941 ttttggtgcc aaacataccc agatttgtga tggagaaggt tgagcctgac atttcggtag
    15001 cctttagctt gcctccttga gcctttttga taacgtcctt agaagcaagg acaaactctg
    15061 agagactcat cttatctgca ccatgaacaa ctggcacaac tagcccatca tcaagtccta
    15121 cagcaatacc aaggttgaca aagcgatgaa gctcaatatc attagcatca ttaatcaatg
    15181 acgcattcat gtattcgtgc tctggcttca tcaaggtctt aacaacggct aaaccaatca
    15241 agtcagtaaa gctaaccttt agccctgttt tagccatgat tgggtcaatc agcttcttgc
    15301 gcaaggcaat catttcggtc atgtcaatgt cataattaag cgtaaaggtt ggtgctgtaa
    15361 ggtaggaatg tgtcataccc tttgaaatag ccttacgcat agcagacatc ttcttaattt
    15421 caacaccctc tggaagctcc ttagcaggct tttcttcagc aatagatgct ttttccacag
    15481 caggtgctgc tgcgccaagc acagccaaaa tgtcctcctt ggtaatcttg ccaccaatac
    15541 ctgttccgac caccgctgca aggtcaactc ccttgtcggc agctatctta cgagcaagtg
    15601 gcgttgcctt aggctgagct cctttgaagc cttcaacgtc ttctttgtgg atacggccct
    15661 ttggtcctgt tcctggcact tggttaagct caattcccat ttctgaagct gctttacgag
    15721 ctgctggcgt tgcgcgtacc ttttctccga aggctggagc attggcaact gatgctacct
    15781 gaggcgctgt tgaggctgct tctttcggta cagttgttgt attagcttct gctgatgttg
    15841 gtactggaat ttcagttgtt ttctcacttg aagcagtact attatcaaca gattcacctg
    15901 cagcaccaat atagccgata acctcagtga cagggactgt ttcacctgcc tggcgagtga
    15961 tttttagaag cacacctgaa tcctctgctt caagctccat atttgtcttg tctgacatga
    16021 tttcaagaag aatgtcaccc tcgctaacag tgtcaccctc ctgctttttc cactcgatga
    16081 tctcgccttc ttgcatgtca acaccgagct ttggcataat aatttcgaca gccatatatt
    16141 tcctttcatt taatcccgca gcccatgatc ttaagaccag atacagctgc tgaaaaaagg
    16201 gatactgttt tatcagcctg atgaagaaag cctctaagct aagacttcct ttgccatgct
    16261 aatttccctt gttgaccatt tttacaatag cagccttgat tttagcaaca tctggtaaga
    16321 tagcttgctc aagaacacgt gcataaggta ctggtacgtc ctcactagca agacgcacaa
    16381 ttgggtgatc aaggtaatca aaggcttcac tttcagtgac cattgctgca atctcaccga
    16441 taaagccacc agtcttatag gcatcattaa caagcataag cttccctgtc ttcttaacag
    16501 aattaataat taattcctta tctagtggga taagggtacg tggatcaaca acctccacat
    16561 taataccatc agctgcaagc tcttcggctg cctgaaggac acgctctagc atacgcccat
    16621 aggaaacaat ggttacatca gtcccttcac gcttgatatc ccccttgcca agtgggatat
    16681 aaaaatctgg atcctgattg acctcttctt ttttaccgta caaggcctta ggctccatga
    16741 aaataacaat attgttatca cgaatagctg actttaaaag tccctttgct tcgttagcag
    16801 ttccaggtgc aaccaccttg atcccaggaa tatgcgtcaa ccaagcctca agagattgcg
    16861 aatgctgagc tgcagatcca attcctgagc cagaagcaac acgaaaagtt gctggcgtga
    16921 tcaagccacc accaaacatg tagttgtttt ttgccccatt attaacaatt gcatcaagtg
    16981 caatggtaat aaagtccata aaagtaaggt caacaatcgg acgaagccct gtaattgctg
    17041 aaccaatcgc tgcacctgca atagcagcct ctgaaatcgg cgtatccttg acacgtttgg
    17101 caccaaattc ctcaatcatg ccaacagaag taccaaagtc tcctccgtaa acacctacgt
    17161 cctcacccat aaggtaaatc gtgtcatctt tgcgcatctc ctctgtcatg gcaagattga
    17221 tagcctcacg caaagccatt aattttgttt ctgtcattat tatctcctaa tgtttacaaa
    17281 atagaattgt caatgttact gtgaatagat ttttgctcga tgtgctagca gatcagctag
    17341 tctacccaaa cgtcctcaaa ggctacagaa atgtctggat ctggactatt ttgtgcaaac
    17401 tcataagcgt catcaatttc ttgcttgacc tgtgcttgaa gcgcatctaa ttcttcatct
    17461 gtagcaatgc cttcacctgt taggtaagcg cgatacttaa gcattgggtc cttttccttc
    17521 cactcatcaa cctcttcttt ggtgcggtat ttgccggcat cagcagttga atgaccaaac
    17581 caacggtaag actcaacctc aacaacagca ggaccattgc caccgcgaac atgctcaaca
    17641 gccttactca tggtttcata aactgccatc acatcgttgc cgtcctcaca ataaaagcct
    17701 ggaataccat aagcctcagc acgcgtgtag aggtgaggtg tatttgtggc attgttaatg
    17761 ctcatggaaa tcccatagcg gttgttaatg ataaagaaaa tcacaggaag cttccaagtt
    17821 gctgccatat tgacagactc atggaaggag ccctcatttg ttgcgccatc tccagaaaag
    17881 gccacaacga tattgttggt ccccttgtat tgctgtgtca aggcagcacc taccgcaagg
    17941 gcatagccac ctccaacgat accatttgtt ccatagtttc ctttttcaaa atcagccaag
    18001 tgcattgagc cgccgcgtcc ctttgacaca cctgttacct taccggctag ctcagccatc
    18061 attttattga ggtccatatc tttagcaata gattgcccat gcccgcggtg gtttgaaaaa
    18121 ataatatcat cataggtcaa atgtgccaca gcgccaacgt ttgctgcctc ctcaccaact
    18181 gagaagtgtg tcatgccctg cacaaatcca cgacggacaa gcttattaat acgtgaatca
    18241 aattcacgaa tacgctccat tttaaggaac atatctaaat gttgttcttt agaaactgtt
    18301 accatttcgg cctccatatt atcatattac ttcctaatca taaaactttt cttcacaatt
    18361 tgcaaggatt ttaatcgctt tctttgtgac tataaaagct tttttaagac gttttagttt
    18421 gtggtttcac aagctagatt gttatagcat ctgttacatt tatatataac agattgaaaa
    18481 atgagtcagt gtttattcag ggaggtcaag cacctattga ctttgatagt cagaaatatc
    18541 atcactcttt aagaggaaaa taggctctaa atgacctgtt tcttctagca caatcatgat
    18601 cacctaccaa acgaacgctt tgcttgcctc gctccgatag aggcgaaatg aactaaaaat
    18661 cgcataacta aaaatgcctg attttacctg aaaatcagac atttaaaagc tttaagacat
    18721 tagactcagg ctctaattat aatcctctaa gaaaagcctg ctaccttgca ctacccaaga
    18781 atagcaaggc aatttcatta tctcaccagg ctactccagc tgtcctgcaa tgtcctccca
    18841 ctccagcagc aaggtctcct gtttctgatt aagctgatcc aactcttttt gccagtctat
    18901 cagttgagtc gtatcatttg atactagcat ttgagcttct atagccttag cctgtgcttc
    18961 tagcccttct aaggtctgct caatctcctc aaagcgcctt gttaagcgac ggtattcctt
    19021 ttggctggcc ttttgaagct gataatcagt tacagcagct tctgctacat cagtctctac
    19081 tacgtgatct gcagcagcta gacgggctaa ttcctcccgc tctgcctttt tttctacata
    19141 atagtcgtag tcccccagat agagtgttga gcctgcttca gttatttcta aaaccttagt
    19201 ggccactcgg ttgataaaat acctgtcatg actaacaaac aacaaggtcc catcaaagtc
    19261 aatcaaggca ttttctagaa cctctttgct atcaatatcc aggtggttgg ttggctcatc
    19321 tagaatcaga aaattgtcct ttttcataga taattttgtt aagagcagcc gagccttttc
    19381 gcccccagat agcatggcca cagacttttt gacgtcctca ccagaaaaga gaaaggcacc
    19441 taagcggctg cggatctcaa gctcagctgt cgttgggaaa tcacgccaaa gctcctccaa
    19501 tacagaatta ctaccagtca gatgagattg cgtttggtca taatagcctg tttcaacatt
    19561 agtcccataa tggcatgtcc ctttaatcaa aggaatctct ccaataatgg atttgagtag
    19621 ggttgacttg ccaataccat ttggcccaac aatagcgatt gcatctaacc tacggacatc
    19681 tagatgaatt ggctcagcta aaatatggtc attgtagcca atagcggcgt ctgtcacctg
    19741 caaaacaaca tttcctgagg gcttatcaat ctgaaaagtc atactagctg atttgcgaga
    19801 gctacttggc ttgtctaagc gttctagctt ttctagctgc ttgcgtcttg cctgagcacg
    19861 cttggtcgtt gacgctcgaa caatgttttt ttggacaaaa tcctctagct tagcaatctc
    19921 tttttgctgc ttgtcataat gcttctcttc tgctgcaagc ttttcagcct ttaaatcaat
    19981 aaagcgtgag taattaccaa catagcggtc taagctattt ttagtcagat caagtgtgat
    20041 ggttgcgacc ttatccaaga aatagcggtc atgactgaca atgatcaagg ctccctgata
    20101 atttaccaga taatgctcca gccaggcaat ggtttcaata tctaaatggt tggtcggctc
    20161 atcaagcacc aatagctctg gcttttctag tagcattttt gccagggcca aacgggtatt
    20221 ttgcccacca gaaagctctg agattttcat ttcccacatg ctttcgtcaa acttaaagcc
    20281 atttaaaata gctcgaatat ctgactcata ggtgaagcca tttcgcaagc gaaagctttc
    20341 tgacagccgg tcatagtctg acatgagctg gtccagagct tgccctgatc gactggccat
    20401 atcagcctcc atttgcctta gtcgctgctc atcaaccctc aattcagcaa atacctttag
    20461 catttcctga taaatggtct tgtcagactc aaatcggcta ttttgtgcca aataagatag
    20521 ggttaagtcc ctttttcgac taacctcacc gctagttggc tcttcttctc caactaaaat
    20581 cttaagaagg gttgatttgc cagcaccatt tggcccaacc aaggcaatgc gatcacgttc
    20641 accaacctgc agcgataggt tttgaaaaag cacctctcct gaaaaagagc gctcaatgtt
    20701 atttccttgt aatataatca tacccttatt gtagcaaaaa aatgcccttt tggggggcac
    20761 ttttagttat ttttacaggt aagataagac tcatcaacaa gctaaagaca taagccttag
    20821 gctaacatcg cttatcaccc ttagtggtat ttatctgatg agacaaactg ctgcttgaaa
    20881 aaccagtggg ttgacctgtt agcgtatcca acaatcgcac cacctgctca gttatgcttg
    20941 aaatgctatt agccagtgag gaatcactat ggttcgaata ataaatcaaa ccaaaaataa
    21001 gcaataccaa tactattagg gtctgcaaac agcctctgac aagctgccag acaagcttca
    21061 gcagaagctt tgggaggcat aagaggatag tcagtagttt tttcatcgta ataagcctaa
    21121 attctttcgt ttaggatagc ctttcttcct tgtggtaagc aatcggcagc caatctaata
    21181 gggcctctag ctgctgattc caataatacc attcgtgcct gccatgatcc ttacgataat
    21241 caatagtcaa gccaagcctt ctcaactcag caactgcctt ttcattggct tcaaacaaaa
    21301 agtcctcata gccacaccaa gcgtatagct gggtttgacc atcactttct gctgctatac
    21361 ttgtcaaata atgctttttg atatcaggag cattcaaatc tccaaaaaca ccctgccaat
    21421 aaggcagctc acctatacct tgctgtaata gcatttccgg cgaaaaatgc aaggccccag
    21481 aaaaggaagc agcataggaa aagcgattgc tttttaaggc ccatttaaag gcaccatagc
    21541 ctcccattga cagcccagca acaaaggttt tttcacgctt agtggtcata ttaggaaaga
    21601 aagaagctaa tagccgagga agttcctctg caatagcttg gtaataattc ataccgtagg
    21661 tggtatcggt ataccagcct aaatcagtcg atggcatcac cacgattaaa ttggtatggc
    21721 gaagcagcct ttcaatatta gtccgctttt gccaggaatt ttcatttcct cccataccat
    21781 gtaacagata aagaactgga atatcttggt agccttgctc ttctgggcta agctcagact
    21841 gatcagggta gatcaccttg acatgtcttt ccatagccaa gatctctgaa tgatactcaa
    21901 tgctaatgct tgccatcagc tcacctcctt tttaatatca ccaaagcata aggaaagccc
    21961 actcttaaga cctaaaagcc agatcctatt tgaccagctt ttaggcaggg ctgtatctgt
    22021 attaacggac ctccataaca accggaagaa tagctggccg acgcttggtc tgctcaaata
    22081 aaaaccttga gagctcctct ctaacagagc ctttcaattc actccaatca aaatgatccc
    22141 cttgcagata attgccaact gttgtgttga ccaattcagc actttctcgt aaaatatctc
    22201 tgctcttttt cacatagaca aatccgcgag tgttgacctt agccttagag ataatacgtt
    22261 tttccttttt agatactgtg atcgcaacaa taaaaatacc gtcctctgat aagaccttac
    22321 ggtctctcaa aacaatattg ccaacatcac caatggcatt tccatcaatc atcacatcac
    22381 tagcaggaac cgcaccctcg tgtaagaagc catcctcatc aagcaccatg atgtcaccac
    22441 gcttcataat atgaatattt tcaggtagta taccagcctc ctcagctaaa tgagcatgag
    22501 cagctagatc gcggtattca ccttgaatcg ggaacaggta ttttggtttg acgagattaa
    22561 tcatcagctg caggtcacgc gcattggcat gtccagaaac acgtaaatgc tgcgtgatga
    22621 gcttaacaga gccacctgct ttatagataa ggttttcaac acgagcaacc attgcttcct
    22681 tggcagcgct tggcgttgtg acaatgtaaa ccagatctcc gtccttgatt tgcacgtggc
    22741 gatgacgccc tattgccatt ttctgtaggc tattaatcgg ctcacccata cgtccagcct
    22801 ccagaacaat caattcgtga tcctcaaact tagacatatc ctttggcttg attaatagct
    22861 tttcatcagc aatcactagc tttttaagac gaagtgctgt tctgacaata ttttcagcgt
    22921 cagtacctgt cagtaccact cgcctgctat aggctgctgc agaatcaaag acctgctgga
    22981 tacgaacaag atttgaagcg acagctgcaa taataatccg cccgtcggca tgagcaatca
    23041 ccttatccat ctcctcgcca acctcagctt cgctggcagt ctgctcattg cttgtggcat
    23101 tggccgagtc agctaatagg gctaacaccc cttcttttcc aatgtctgcc aagcgagcta
    23161 ggtctgtctg atagccctca cgcgaagcct ggtcaaactt gaaatcacct gtatagacaa
    23221 tattcccctt atcggttcca ataaccacgc ctaaactttc aggaatagaa tgtgttgtct
    23281 taaagaagga aaccaagcca tctttaaatt caatttctgt gtcactgtcg accacatgga
    23341 aattcttaaa tctcttggtg ctattattgg ccttgacaaa caattttgct agctcgatgg
    23401 tcaattctga accaaatact ggcactggaa cctccgccaa caggtaaggc aaagctccga
    23461 tagcatcagc atgcccatga cttaaaaaga ctccctgaac cttgtccttg ttttcaatta
    23521 cataatcaag acttggaatt accaaatcta cacctagctg ttctgtttca gggtatttca
    23581 agccagcatc caaaatgaac atggaatcgt taatctctac tagatagaag tttttcccgt
    23641 actcacgtac gcctcctaat gcaataatgt ttatatcagt catgatactc ctttttttat
    23701 attagttatt acaaacggtc cttactgggt aagtcgaatt actgtcttgc agctaagctg
    23761 cactctttta cagtatatca tattttaggg cttattacct caaattgcct tgagactttc
    23821 tcaatctttt caatagatta tcaaaaaagc caagggaagg ctttcattcc aatggctttt
    23881 agagtattta ttttagtcaa aaagctggta ataatcagca atggtcattt gagattttct
    23941 cttctgatca aggtcttgaa tgattttacc atttttcatc acaatcaggc gattaccata
    24001 gttaagagcg tcctccatgt gatgcgttat cattaaggct gtcaagcgat ccttagctac
    24061 aaaatcatca gtcaaggcca ttaaggcttg gctggtctta gggtctagcg ctgcagtatg
    24121 ctcatctaat agtaaaagct ctggtctttt tagggttgcc atgagtaagc taagggcctg
    24181 tctttgaccg cctgataaga gaccagtcgg agtctccaga tgattttcca agccatttcc
    24241 aactcgcttg accaagtcag caaagtctgc catataatgg ctaatcctgc gtgatgacaa
    24301 gcctcgcctt tcccctcttt gccttgcaat caaaaggttt tcagctactg tcattcgagg
    24361 tgctgttccc attttaggat cctgaaaaac acgtgatagg tagctagctc ttttttctgc
    24421 tggcaggtgc gtcacatcat gccctaaaag cttaatttga cccttgctta acaatagcgt
    24481 cccagcaatc acattaaaaa gggttgattt accagcgcca ttcccaccaa gaatcgttaa
    24541 aaaatcatgc tcataaatgg tcaaggaaac atcatctaaa atagccttag tctcatcaaa
    24601 gccattattg acttcgacag tagcgtgaat taattcaata atttttctca tcgtgataag
    24661 ctagcctcct taataattgc tttttttagc acaggcacca tcaggcaaag tgctaatata
    24721 atggcactaa atagcttaag ataatttgta ttaaagccaa gagcaataac tactgagatt
    24781 aaaaattgat acaggataga accaaccaca atggctatca agcgctcaag cagggttagg
    24841 cctgtagaat ataaaacctc accaacaata atactcgcaa ggccaattac aatcacacca
    24901 atcccctttg aaacatcagc atagccatct tgctgactaa ccaaggcacc agataaggct
    24961 atcaaggcat tagagatcgc taagcccata agctccatac gatcagtatg aatcccaaag
    25021 ctcttagcca tatcccgatt atctcctgtg gcaatataag cctgaccaat attggtgtaa
    25081 agaaaataca ttaacaaaaa aatcaccaat gtagctacaa ccaaaccagc taccaacaca
    25141 ttggtgtcag ctgcaaaggg aaggtagtcc tgaatgcgct tgatatcatg caagcccaaa
    25201 ttggccctgc ccataaccat aagcataatg gaatggcagg aggtcatgac tagtatgccg
    25261 gcaagaagtg ttggtatctt tccttttgtg tataacaggc ctgtggcgaa gcctgccaag
    25321 gcacccgcca gcatagcagc cagagtagcc aggataggat ttaaaccgag attgagcaga
    25381 gttactgcta cagcacctcc taaaggaaag gacccttctg ttgtcatatc tgggaaattc
    25441 aatattctaa aggtcaggta aatccccaag ccaagaattc cccataacaa gccttgtgat
    25501 acagatgaaa taatcatatg aactcctttt ctattgctta cctgtaaggt cagaacgctt
    25561 cagcaggtct tttgagatca taagacctaa atcccttgct gcctttagat ttaaaaatgg
    25621 cttaccgtca tcaactacct cgacaggaac ctctgatacc tcttttccag ccataagctg
    25681 cagcacctgc ctagctgtct caacccctaa ttggtattga ctttgtgaaa tagaagcaag
    25741 actcccttgc tcaaccattg tatcaacact tgagtagacc ggaagctgtg ctgcatttga
    25801 ggcaacaatc accgctgaaa aagcactggc aatagtatta tcctgtggga taaaaacagc
    25861 atctaccttc tcagtcatca cagacatggt cgtggtaacc tcatttgttg aggggacagc
    25921 gtaagctaga acctccaagc cttgcttttc tgcaagagct gtaaagtcct tgacctgtga
    25981 tattgaattg tcctcactgc ttgcataaag gacaccgacc cttttgacct gaggggtcat
    26041 ctccttgatc agatcaaccg tctgtcgaac aggaacctta tttgataagc cagtaacatt
    26101 tgcctcaggc ctgtctaagt gcttgactaa tttagcacca actggatcag aaatagctga
    26161 catcacaacc gggatagtct tggttgctgc tgctaatcct tgagctgcag gcgttgcgat
    26221 gccaacaaca atatcgtttg ttttgaccag ctgcttgctc atggtctgaa tcttactttg
    26281 atctccttct gcattcataa gggtaatgct gaccttttgc tctggctgat gatgcttctt
    26341 tagctcgtct ttaatgccct gtgcaatctg gtcaagcgcc tcatgagtaa ccagctgcaa
    26401 tataccaacc ttaaccacac gcttgctggc taactgtggc tgttttttgc cctcttttag
    26461 cactagcgaa gcagcaacca ttaaaaagag tgcaatgact gttacgataa gacctttatg
    26521 tttcatgttc tacctcttaa tttccattct tactccgttg ctaacattta gagtactcac
    26581 aaaaagaaaa aacgcttagt aatcagctac taggcgcttt ttttgaaatc caatgtcagc
    26641 gcatagatac ctttttagaa gtactctaaa agtcgtatct atgctaaccc ataaacacaa
    26701 ctttatctat gccagctttg ccaatttatc atatgctgtg tttgcttcat cttggatttc
    26761 ctttcttgtt tttttacatt ataacctaaa agctcaaaaa tacaagagca tttgaacata
    26821 tttttccatt attttttgtg gtataatgaa agaattagaa ctcaggaggg agaaaccatg
    26881 tcatttgacg gctttttctt acatcattta actcaagagc tcaaccatag tattgttaat
    26941 gggcgcattc aaaaagtcaa tcaacccttt gataatgagt tggttctgac tatccgtaac
    27001 catcgccaaa cttacaagct cttgctctca gctcatccgg tttttggacg cattcaactg
    27061 acccaaacag actttcaaaa tcctcaattt cccaatacct ttaccatgat catgcgcaaa
    27121 taccttcaag gagctatcat tgaaggcttt gagcagattg ataatgaccg catcatcgaa
    27181 atgaccgtct ctaacaaaaa tgagattggc gatgccataa agacgacatt gatcatcgaa
    27241 attatgggca agcacagcaa tattattctg gttgaccgtc atgaaaacaa aattatcgag
    27301 tctatcaagc acgtcggctt ttcccaaaat tcctaccgga ctattttacc aggatcagcc
    27361 tatatcgagc ctccgaaaac aactgctgtc aatcctttta cgatctcaga tatcgcttta
    27421 tttgaagtcc tgcaaacaca ggagttatct gctaaaaatc ttcaaaagca tttccaaggg
    27481 cttggccgag ataccgcaca agagctatcc agtctcctga caactgataa gctaaaacgg
    27541 tttagagact tttttcaaag acctagtcag ccaagtctaa ctcagacctc ctttgctcca
    27601 gttgccttct caaacacact gaagaccttc cagaatctat ctcagctgct agattattat
    27661 tatcatgaca aggctgagag agatcgtatc aaccagcagg ccagtgacct gatccaccgc
    27721 gttcaaaacg aattggaaaa aaatcgcagc aaactgatta agcaagaggc tgagctgcta
    27781 gccactgaaa atgcggagga ctttcgccaa aagggtgagc tcttaacaac ctatctgagc
    27841 ctggtgccaa atgaccagga ttcagttgag cttgataact actataccgg ccaaaaaata
    27901 accattgcac ttgataaggc gttgactccc aatcaaaatg cccaacgcta ttttaaaaaa
    27961 tatcaaaaat taaaagaagc tgtcaagcac ctctcaggtc tcatcgctga cacgcaacaa
    28021 accatcgctt attttgaaag cgttgattac aatctatctc aggcaacgat tgatgaaatt
    28081 gaggacattc gagaagagct tattcaggct ggctttgtga aaagccgtaa gcataacaag
    28141 caccacaaac gtaaaaagcc agagcaatac ctggcttcag atggcaaaac aattattatg
    28201 gtcggacgta acaatctgca aaatgaggaa ttaaccttta aaatggccaa aaaaggcgag
    28261 ctctggtttc atgctaagga tattcccggc agccatgtga tcattaagga caatctaagc
    28321 ccaagcgacg aggtcaaaac tgatgctgct gaattggcgg cctattattc taaagcaaga
    28381 ctttccaatc tcgttcaggt ggacatgatt gaagccaaaa agctgcacaa gccaagtggt
    28441 gcaaagcctg gctttgtcac ctatacagga caaaagacac taagagtgac acctatagaa
    28501 agcaagattc aagccatgaa gtgctcccct tcagcctctt cctcatagga ctacagcaat
    28561 aaagataaaa aaagctacag cctcacactt ggagataggt ccagtcttaa agctgcggct
    28621 tttttatcat tacttgttaa tcatctctca aatcatctaa gaagccttgc atatgaatat
    28681 catctggaac ctgctgcaaa tacctttttg cctgcttaac tgcttgatca gtatagccga
    28741 attcccttaa taaataagca taatcctgta aaaagtcagg attttctttt aggtctcctt
    28801 cgatatcttt atagatagtg agggcttttt cttgctgctc cagagcctga taggccttgg
    28861 caagattcca tttagttagc acatgatcaa tctcctcatg ctcaagagca atgacctcct
    28921 caaaacgctc catatccaag tacaggctag ataagcgcat gatgacctct tcgtcatcaa
    28981 cagctacttc cttggccctg agcaaatacc gctctgagcc agctggatca tgcaattcaa
    29041 aggcaagctg tgaagcaagc aacagcagct gggggtcaaa ggcattttta cgcagaccct
    29101 gctgaactag gcgtaaggcc tcttctgtcc gatgctcctc acgcaagctc atggcatagg
    29161 ggtactcgta gcctaaaaag tctgcattca tcgtttctaa ttgcttgaaa tagagattgg
    29221 ccttttggta agcagcctga tcatataaaa tcgtcgccag ctcaaacact gtctcatcgt
    29281 catactcaat ggcaagagcc ttttcaagaa actctacagc agcttcaaat ttccctaaat
    29341 aagcataggc acgccctatg cgctggtagg ttgagatacc tgtcagctca agaatgtgac
    29401 gattatcaag cctagcatat tgctcaatag cctcgctaaa gtgctccaga gacatctcga
    29461 tttcggctaa gccaaagatc actatcggct cctgactcaa ttcagctgct tgaagtagct
    29521 tctcacgcgc cacatcagtt agcccctcca aatcataaag atcagccatg acgagcagag
    29581 cagacaaata atcagcacta tcctctggaa tcctatcaag gtacataaag gcctcttcaa
    29641 tgacattatc ctcagctgca atctgagcaa gattaatatt gacctccgga taagcctcac
    29701 agacctgcaa ataaatcgtc ttagcatgca gtaaaaaacc aatactctct aggtattctg
    29761 ccaaagccaa caaggtctca gcatcgtcct cctgcaaggc tctttgaaaa tagctttctg
    29821 cctgctctaa atcctgttgc tctagtgagg caatcatttt ttcactattt aacatcttca
    29881 gcgaccctct cagcttctgt aggctcttcc tcatacaggc ctgtaatatc cttgtaccaa
    29941 tcaaatagct ccttcacaac aaccttaaca gaagcataaa ctggaatgac aagaaagaca
    30001 ccccagaccc caaacattga ccctgctgtc aataataaaa acataatggt aatcgggtga
    30061 atgctcagct tatttccaag cactagcggc gcgacaaaac gtccttcaat cgtttgttca
    30121 ataacaaaaa taatcaacac cttgatcagc atcaagggtc cttgcaccat tcccataatc
    30181 actacaggaa tcatggctaa aaagctcccc agataaggaa tcatattaag aaagcctgca
    30241 ataataccaa aggtaataga atagttcaaa ccaacaaggc taaacatcac tgaaaacatg
    30301 agaccaacca caatcgcaac ggtcacctgt ccctgcacat agccagataa ttgcttgttg
    30361 atttctccta agacacgtgc cataggctgg cgcagcttaa tcggaagcac attgaccaaa
    30421 ccatttttca tatggccact gtcacgcaga aaataaaaga gaataaaagg tgacatgatg
    30481 attgcaacag taatacgggc aatagctcca gcaaaatttc ctgcccaatc aatagcattt
    30541 ttagagaagc tttgcgcata atctagagcc ttttggctca tactagtcag catatcctgc
    30601 aggttggacc tgtagctaac cagccattcg ttttcaagta gcttattagc ctctagattg
    30661 accttggcaa catatttggg aaggtcttcg acaaagctcc ttagctggtc ttgaatcata
    30721 gggataaagc cagaaatagc ccagaaaaat aggagaatta ctaagccaaa gacaataaaa
    30781 atagaggctg tgcgatttgg acctagcttc tcaaccatat caactaatgg cttggtcaaa
    30841 taatacagga tagttgagat aaccagcggc agcatgataa tggccaaaaa tgacaagatc
    30901 ggtgtaaaga ggaaggatat ttttgtaaag acaaaaatag tcagaaaaac cagcagcgtg
    30961 attaacaaaa ccatcaccgc ctgattattt aaaaaccatt tgtaaaatag actatcatga
    31021 tgattaggct tagaatgcaa tgacattaat ggtatcgtcc tttcttaatt gtggcatcat
    31081 tctgatgaga gcttttaggt tagttgactt aataaaaggt gactgttttt tccactagct
    31141 tgttgtggtc atcataccta aatttagcag aaaaaaacgg ccggtcttcc agtatccact
    31201 tgaaaatgtc gtaatctccc tcccaggttg gcttttccag cacctgatca tagggaaccc
    31261 attctagggt cccttctctg gactcctcat cagcaattaa gtcaccttca aagtctgtca
    31321 ccttaaacac gtaagtatac caatcatgcc ctggtgtaaa atcaggaaag gtaatcactc
    31381 ccttaaagtc cattgctttt accagcaggt gagtttcctc taaaatttca cgtctggcac
    31441 agtcatcagg agattcgcct ggctctaatt tgccaccaac tgaaatccac ttaccttggt
    31501 gaacatcatt ttccttcttg ttgcgatgca gcagcaataa agcctcaccg ttatcaatat
    31561 aacaaatcgt tgctaactta gtcattcata cccttccttt gtttagttgt tactattata
    31621 ccaatctctg agaaatatgc catcatttta tcatttaagc acatcaaaca agaaaaccac
    31681 aatcactaca actcttagcc ctgtactagc aaaaaagcct tgataaggca acgtctgctg
    31741 actcatcaag acttatcact atttaacgaa tcacttcctg tgtcttagcg taattggctt
    31801 caactgcttc tttttcggaa cgccaccaat cctgatgatc agtataccat tggatcgttt
    31861 gctcaagtcc ttctgaaaaa tcagtaaact gtggctccca gccaagctcc tgacgaagct
    31921 ttgtcgaatc aatagcatag cgtaaatcgt ggcctgcacg atccgttaca tggtcataag
    31981 cgtccttagg ctgccccatt ttatccagga ttaattccag cacttcctta ttattttttt
    32041 cgccgtcagc tccaataagg taggtctcac caatacgtcc cttggtcaaa atggcccaaa
    32101 caccagttga gtggtcattg gtgtgaatcc agtcacgaac attctttcct tcaccataca
    32161 attttggctt gataccagac aagatattag tgatctgacg agggataaat ttctcgatat
    32221 gctggtaggg accataatta tttgaacagt ttgaaatggt tgccttcacg ccaaaggagc
    32281 gaacccaggc cttaacaatc aaatcagagg ctgccttggt tgatgaataa ggtgacgacg
    32341 gattatagtt agtatcagcg gtgaattttt cacctggccc ctcaccatga cctggcaaat
    32401 cctcacgcag tggcagatcc ccataaacct catcagtgga cacatgatgg aagcgaatat
    32461 catatttacg agccgcctct aagagtgtat aagtcccaac gaagttcgtg taaataaatg
    32521 gacttgggtc attgagtgaa ttatcattgt ggctttcagc agcatagtgg acaatagcat
    32581 ctgccttagc ggccagctta tctaccaatt cagcatcagc aatgtcacca acaaccaact
    32641 ccacgcgatc acccaaaatc tcctcaaggt tggcacgatt gccagcgtag gtgagcttat
    32701 ccaaaacagt tacgtgaacc tctgggtgat ggttgtaaac ataatgtacg aagtttgaac
    32761 cgataaagcc agcgccaccg gtaacaataa tgtttttata ttcagacatg ttttttcttt
    32821 tcctttgttt tcagctatca gcactcaaaa tgcagcttaa tccgacaggc aagctcagtt
    32881 accagtgaaa acagcgacta agctgcctca cctcattgct cctaccatcc ataaggtcct
    32941 tcctatcaga aggatacaga gacactccca tcaaaagcca tagcttattt caaatgctaa
    33001 ttatgataaa tcttcttgtc tcaaaggctt aacggcctct aggaagggat ggcttttatc
    33061 tgcttctgaa acctctgctt gttcaagact ttcccacgca atcccaaggc ttgggtcagc
    33121 ataattaaca aaggcatatt tttgcttgag ctcaagcgcc caataatcat tgaccagata
    33181 ggtataagcc accttatcag tcagtacttg aaagccatta gcaacacctc gagggacaaa
    33241 aatccccttt gaagcgtcaa tgactgtttg ataggtatgc ccaaagctat caccctcacg
    33301 aagatcaacc caagctccaa gaaccttacc ctcatcagca acagagatgt acttgtccca
    33361 aggctctgca tgcaggcctc gaagcacatg cttgcgcgaa aatgaaatat tgttttgcag
    33421 cttacctgcg gcaaaaaact gctcaggaaa gcctagagga atcatttttt ccttttgaaa
    33481 attttcctta aaccagccac gattgtcccc tcgaacaggg atatcaaact ccaaaagtcc
    33541 aggaatggct tcaatttccc gacaggctaa ggctttatca aaaaattgtt ctgtcatcaa
    33601 gcttctccaa tcaaccgcag caggtactgc ccgtattcgt ttttcttaag cgactgcgct
    33661 agctggtaga catcttcttt agtgatataa cccatgcgat aggcaatctc ctctaggttg
    33721 gccacctgag cgttttgcaa gcgttgaact gtctcgatgt attgggcagc ctccagcagg
    33781 ctttcatgag tgccagtatc tagccaggca aagccacgtc ccatcaactc aaccgatagg
    33841 tcgccacgct ctaaataggc tttattaaca tcagtaatct caagctctcc tctggcactt
    33901 ggtttaatgc ttttagcaat ctcgactaca tcattgtcgt aaaaataaag gcctgttaca
    33961 gcaaaatgtg acttaggaac tgccggcttt tcttcgatag aaatggcatt catctcatcg
    34021 tcaaactcca caaccccaaa acgctccgga tccttgacct gataaccaaa aacagtggct
    34081 cctttttcct tagctgctgc cttttggagc attttcgtaa ggccgtttcc atgatagatg
    34141 ttgtcaccta aaatcaaggc aactcgatca tcaccaataa actcctcacc aatgataaag
    34201 gcctgtgcta agccgtcagg acttggttgc tccttgtagg acaagcttat cccaaactct
    34261 gagccatcgc ctaatagctc ttcaaatctt ggaagatctt ggggagttga aataatcaaa
    34321 atgtctcgaa tccctgccag catcagtgtt gataagggat aataaatcat tggcttatca
    34381 taaattggca tcaattgctt tgaagctgca cgagtaagag ggtacaagcg tgttcctgat
    34441 cctcctgcca gaataatacc tttcatcgta gctctcctca ttttataata cgtcactatt
    34501 ttatcatttt ttaaaaacag tgtcactttt tatcattaat ccgacgaata taatgatgaa
    34561 tcgggtattg actagtatct aagctagctt tttgccccaa aagcagggca atcagctgct
    34621 gagcaatcaa aggacctagg gtcaagccag atgagcctag accgcttgcg gcgtaaacac
    34681 ctggtagctg aggtacctgc ccaaaaaatg gagaaaaatc tctggtatag gctcgaatgc
    34741 ctacgcggta agaaacatca gaggcagaac tcagcttagg gtaataggtc aaggcctcct
    34801 gctccaaggc ctctaaaaca gctacatcag gctcaaggtc atagccctta tcattttcat
    34861 gactcgctcc tacagacaac ctatcatgct caaagggaat aatatccagc tccccctctg
    34921 gcatgaccac tgcgtagtta tctgtagtca cattcgcaat gtgataatca atgagctgtc
    34981 ctttttgcgg tcgaatatcc acctgatagc caagtggctc aagcaattct ggcagccaag
    35041 caccagcggc tagaatcagc cgatcaaaga ccataccatc aacgagatag ccttgctttt
    35101 ctatgcttat gccaacacgc tttttaacca cctgatagcc actagcttca agcaaacact
    35161 gacataggtc tgccccatca acacgtgcag ccccagaagc ccataccagc tgctcaaaac
    35221 cctgtaaatc aggaaaatca accctaatgt ccgaacgaca ccttatcgcc aaatctccaa
    35281 tcaaaggcga ctcttgcttg cgtctaatgg ccagctggta gagctcctct agcttgtcct
    35341 cattcttttt taataaataa acaccagtct gcttataaaa atgtgtagaa agcccctctt
    35401 tttgcagctc cttgattaag tcctgataac aatctgctcc taaccgagcc agctggtacc
    35461 aagccttatt ccttcttttt gaaaaccaag ggcagataat gccagcggct gccttagttg
    35521 cttgaccatt accatcatca aaaatagtaa cctgctgata cccttgtttt tttaaataat
    35581 aagcggcgct tgaacctaca attccagctc caatgattgc tatcgttgtc attgccgttt
    35641 ccattctatc atactgctta ccaagcatag gccatactca gtcatgctat agatgactaa
    35701 agggatttgt tgacgccttg ctagccataa tggttacttg ccagccttcc tcttttttcc
    35761 aagcctgcat cttggcaagt agtttatcaa taaataagga ctcgatgtga tgccctggat
    35821 caattgccag caggccttct gtcagcattt cctgtgctgt gtgataataa atgtcaccag
    35881 taatataaac ttgagctccc ttagcaagcg ctgcctgata aaatttatca ccactgcccc
    35941 cacaaatagc cactcgcgaa atcaaagggt tttgaccagt atatcgaacc agccgaacca
    36001 catcaagccc aaaggcttct ttaactgtaa gtcctaactc ctccaagctt tgctctgcta
    36061 catttccgac acgtccaata ccatacccat cttgcgtctc aaccaatacc tctgtctgct
    36121 caatgcccaa cagctcacaa aaccaatcgt tgagcccgtc agagacaata tctatattgg
    36181 tatgactgac atagacagaa atatcgtgct tcaccagctc aaggacaata tctcgctgtg
    36241 gcgaggagac caagtccttc aagcccttaa aaataggagc gtgcttggtg ataatcaggt
    36301 ctaccttggc cgcaatagct tcggcaacgg tattttctct cacatcaagg gtgatcatta
    36361 cccttttgac ctccttatcc agagagccaa tttggaggcc acacacatct cctgacatgg
    36421 atagctcaag cggacaatag ctttcatatt tttcgatgat tgttctagct ttcatgactg
    36481 atgacctcct caatcgcttt tattttttga gaaatgctag cgcgttcaac aggcttcgtt
    36541 gctggcacac aagacagggc atagacaagc ttatctcgct ctttttgcca tttagccaca
    36601 aagactgatg acctttcctg agacaagaaa ggaccaaagc gctgctcctg atctgttaga
    36661 ctttgttgac caggctctgc aacaatgatt tcataatatt tgccattttc tgtcatgatg
    36721 gtttcagcac taatacaaaa agcattggca gatagccaag cacgcagctc atcctctcga
    36781 ttattgggct gtaaaatcaa gcgctcaatc ccttgcagct tttccttacc agccgctaaa
    36841 atgtcagcta ttaaacgccc tcccatgcca cagatggtta tgcagtctac agcatctctc
    36901 gcctcaaagg cagctaagcc attagccaga cgcacctcaa tatgctctgt caaaccatat
    36961 tgtgacacat tttttagggc tgatacaaaa ggtcccttga ccacctcacc tgcaatcgcc
    37021 tcttgaatat gctcggtttc aaccaaaaaa ataggaagat aagcatgatc acttcccacg
    37081 tctaaaagct tagcaccatc agggacatag gatgccacat ggcgtaagcg ctttgataaa
    37141 tgactttcca ttttcttaat ccttctaaca actaatcgta tcactattat agcaaaatac
    37201 agaccaatta aaaagaaagc cacatcagac cttcttttta ccataggtag tcttgtaata
    37261 gctgcaatag ctctgtactg ggcaggtatc acacttagga tgcttagcca agcagtgata
    37321 gcgtccaaaa aagatcaaac ggtggtgggt gatgatccaa tccttcttag gaagcttggc
    37381 catcaaatca gcttcaattt cagtaacatc ggcatctggg gcagaaatgt tcaagcgctt
    37441 ggcaatcctt gacacatgcg tgtcaactgc gattgcaggg acaccataaa tctctgccaa
    37501 gaccacatta gcagtcttac ggcctactcc tggtaaggat tcgagctcct tatgggtttt
    37561 tggtacctga ccatcaaact gtgtcagtag ctgctgagct gtcttgatga tattttttgc
    37621 cttattttta tacaagccaa ttgtccttag gtgatcctca acatctgaca catttgcctg
    37681 agccaaatct gaaagctctg ggtagctttg ccacagctta ggggtaacct tgttgactgc
    37741 cttatcagtt gtctgcgctg ataggataac cgtaataaga agctgaaagg gcttttcttg
    37801 gtcccaattc agctcgccct tagcctctgg aaacatctca ccaatgattg atagaacctt
    37861 ttttaatcgt tctcttccta tcctcattag ttactccaaa ggttcatcgc cgcaagaaaa
    37921 tcatctgaaa ccgtcacttc agacgccgtc atatcctctc tggcacgctt tttttcctca
    37981 agctgcctga ggcttgtaat tccctccttg cgccaatttc ttagaatagc ctgaatatat
    38041 ttccaattgg tttttccatt aaagacagcc tctctcagcg cctcacgcac taaatccaga
    38101 tctgtttggt catcatgaat ggttttttcc aaatcctcta gctccatcgg actcaaaaaa
    38161 cgacccagct cacgctcaaa ctcatcaaca agaagtttca attggttggt gttttgctgt
    38221 tcatgctcac ccttttcatc acgcgccaat agctggtcta aagtgactaa tacaggacta
    38281 gcatcaaaaa tgatctcaat ctctccagcc agctctatgg ttttcatatc taataacccc
    38341 tgactggtca aggaagaaat agccttattc acctctgcta cagacttacc caaggcatta
    38401 gcaatctgac taggtgccaa ttcgtcaagc ctagtcgtat tttggagata gaaaaactgc
    38461 caaaccaaaa aatcgtctga gctcttaaaa atatccttgt aatgaaacag taaggcagtt
    38521 ggaaggacca aattgccaga ctgataatgc tctaaaaaac tcataattcc cctgccaaac
    38581 gtaatagccc aacctagctt ttaatcagta ctgccattag caagcactga ttaaccagga
    38641 aaatgcatca ataccttaca atcgtaatca ccaatagcct gacgaccatt caagccgtcc
    38701 agctcaatga gaaaagcgca gccagcaaca atgccgccca gcttttcaac cagatcaata
    38761 gtagccttta ctgtaccacc tgttgctaat aagtcgtcca caataaggac acgttggccc
    38821 ggcttaatag catcagcatg catggtcaag gtgtctagac catactcctt ttcatagcta
    38881 gcagaaatca cctctcttgg caatttaccc ggcttacgaa caggagcaaa gccaattcct
    38941 agctcaactg cgaccggaca gccaataata aagccacgag cctccggtcc aacaatcatg
    39001 tcaatgtcct tatcgcaggc atattgcaca atctcacgaa tagcatagct gtaggccttg
    39061 ccactagcca ttagcggcga aatatcacga aaggtaatcc cctcctttgg gtaattctca
    39121 attgaagcaa tatattgtgt taaatccatc gtaaaatagt ctttctaatg tcttttaaat
    39181 taaaatcttt cctattatag catgaaagtc taaaaaggta aatgattcct aatcatccag
    39241 atcaatccct ttttccttta aattagtcag gcattcctgt aaataggcct cttgatgctc
    39301 aggataaatc ggtgaggtca gtgccacctc ctctaagtcc tcataggcgg caaggctttt
    39361 tcctcggtaa tttttatcct gccagctcac atctggctgg tagccccgcg cctgcatttc
    39421 ctgcataatc aacaggtgat actggtaaag cttataaaga gaatgggcaa acacatagtc
    39481 aaccgtcgca tgtggtctcc cccagcctgc tcctcgcaag gccgcacatt cacgatgctg
    39541 ccccaacaat tgctgccttg gtaggcgtgt gattaaatcc tgatgccaaa gacgcataag
    39601 ctctcctatt tctcttcact agtcattaaa tactgataaa tctcctgcgg actgcccaag
    39661 gccataagct cttgaaactt taccagctct tttagctgtt ggtaaatgac actgtcagcg
    39721 atgctacgtt ttggggcatc agtctttacc ctcatcagcc catcttcgat tactacaaag
    39781 cctaactcct caaaaatttg tatcattttg accaagagga ttttttcaat cttgaggtaa
    39841 tcacttagca aggtcagctt atggcgaaga tcaaattctg ggtattgata gatggtctta
    39901 taaagcttgg caaattgctc tctactgcca tagcctgtta ggtaataagg gcgcttaata
    39961 tgatttttaa agtaaatcgc ttcaaattcc cgatgtctaa aaaggccttt caaggcatca
    40021 atatcgtcag gaacctcatc tatgacaaca accttggcct gctggtcctc aacagctgta
    40081 ggaatatgct caggtgccct agcagtcctt gctcgaatat caaacagctg caccccagtc
    40141 actctagcgt caaccagcat taattgcagg ctagtatgac ctcgccagtg attgatcgca
    40201 agactaaccg ctaattccaa gccctgtgat tgctggtact cctgtatcag atgtccctga
    40261 ccaaaggcca agacatcagc ctcaacggct cctttgctga ccttgaactt caagtgactt
    40321 tgttgctgac caatggtcct tgcctgctta atcgtaaaat cttttaagta aaaaacaggc
    40381 tttttattat ccatgccaaa gggtgctaga agtagcagct tgttcagact atctatactc
    40441 aatgcttcta aatccaattc accattgatc aatagagtgt ttttttcctg accatcgtgt
    40501 cccttggctg ccacgtattg gcaaagtagc tctgatagct cctctaggcg atcagatggc
    40561 agagtcatgc ctgctgcccc ctcatgacca ccaaaggctg taaataagct cctattgcta
    40621 ttaagtgctt caaagatatt aatgctctct aagcttctgg ctgagccctt ggctagcccc
    40681 tcatcaatgg tcaaaacaag aacagtctgc ccaatctcct ccatgatccg accagctaca
    40741 atccctaaga cccctgggtg ccagccagac ttagctaaaa cctgcacagg cttgtctaga
    40801 tcaagcatag ccattgcttg agcaaaaatc tcctgtacca agacctttct ttcctcattt
    40861 ttactactaa tcatcaaggc aagctcatga agctcttcgt catcaaagcc tgtcagtaga
    40921 tcaatagctg gatttggatc gtcaagacgc cctagagcat tgagctgcgg agcaagctta
    40981 aagctaataa catcttcatc aaaatgcgct aagtcaacct ctgaaagctt catcagctcc
    41041 tgcaagccta gtctttctgt ctcttttaga acagccagcc cgtttttgac aaggatacgg
    41101 ttttcacctc gtaggctgac catatcagca attgtcccaa tagcaaccag atctaaaaag
    41161 tctactggaa ttgtctctaa cagagctgaa gccaacttga aggcgacgcc acagccagct
    41221 agtttttgaa agggataagc agcagctggg tgctcagggt gaataatagc aaaggcatca
    41281 ggtagctctg ctggcaggct gtggtggtct gttacaataa catctacccc ctgtgcttgc
    41341 gcaaaggcaa ccgcttcatg gcctgaaaca ccattgtcaa cggtaataat cagcgaaacc
    41401 tgctcttgct cgatgaaata cttgtaaaca ctttgattgg gaccatagcc atctgtaaag
    41461 cgattaggca aataaacaag aggctctgct cccatcattt ccagcgtttc cttgacaata
    41521 gacgccgctg tcatgccatc tgcatcataa tctccgtaga ccaaaatcct ctcaagcccc
    41581 tcaatggcct gacgaatgcg atgaacagct ttttccatat catttagcaa ataagggtca
    41641 tggagctgtg ataggtcagc tgtcaaaaag ctggtaagct cctcttcggt atgaacacct
    41701 cggtcataga tgagctttgc agctgtctga ctaagtccct ttgcctgagc tagcttaaag
    41761 aagccagcat ctggctcctt atcagctatg gtccactgat atttggacgt aatcatttat
    41821 aattaaatac ctttcttgca agataatcag atatagttgg aaacaaggta taacacttat
    41881 gagcaagggc taggctaata ggcagattaa tctctcgttt cttttttcct attgcagcaa
    41941 tgattttttt cgccacagta tccgcctgca gcgtaaagcc tgcaacactg gctaaatact
    42001 gcccgcttgg gtcagcctgc tcaaaaaagg aggttgcaat cgggcctgga ttaacagttg
    42061 tcacataaac ctgcctttct gccagctcca agcgaagggc attagaaaag ccaatgactg
    42121 caaactttgt cgcagaatag atacttgact tggcagaagc tattaagcct gccattgaga
    42181 caatattcat aatatgtcca gagccctgct ctgccatttt gtggccaagc aagcgtgcaa
    42241 aatgaatgct ggctaagcta ttcacacgaa acatggcctc aatctcttct gcagagaaat
    42301 catcaaaggc cttaaaagca ccaaagcctg cattgttaat caaaacatca atcctgccat
    42361 ggcgctggta aagctcatca acaagagcct caatagcagc agggtcttga atagcaatct
    42421 cgtagcattc cttattaccg cgagcctgat atagactgtc taacctgtct ttgctgcgcc
    42481 ctaacaaaat caggtaatct tctcttggaa gctgtctgat gatagcctgt gcgagcccgc
    42541 cagaagcacc tgttatcaga ataattctct gtgccattaa atgatcactt cctctaaatc
    42601 gcgaacaacc ttcacatttt caaaaatagt tgccgcatcc ttttccattt gacgacagtc
    42661 acgtcctaaa aagcgtgctg aaacatgatt cagtaaaaga cgcttagcac ctgcatcacg
    42721 cgcgatttga gcagcctgca tgtttgtcga atgcccatga ttacgggcca ttctttcatc
    42781 acccttcccg taggtggact catgcaccag cacatcagca tcttttgcca atctaacact
    42841 agcagatgtc ttgcgtgtat cgccaataat ggtgatgatc tttccttttc gaggctctga
    42901 aataaagtcc ttggcaaaaa ttttggtgcc atcctctagc tcaatatcct gcccattttt
    42961 aaccttgcca aaaagtggac caaagggcac tcctactgct ctaagagctt ctgcatcaag
    43021 tgttccttct aaatcctttt gaaccacacg ataccccata caaaagatgg tatgtgccaa
    43081 gcgctcagca taaacaataa atttatctgt ttctaaaatc ttgcccatag aggtgtcatc
    43141 aaactcatga taatgaatct gataaggcaa tttagagcct gatatcctga tgctgtttgt
    43201 tacataggat tttatcccaa caggtccata aatctcaagg tccgtctgct cctcactagc
    43261 ttgaaaagcc cgactagata aaaagccagg caagccaaaa atatgatcac catgcagatg
    43321 cgtgataaaa atcttcttga tttttcgtgg cttgattgtt gtttctaaaa tttgccgctg
    43381 ggttccctcg ccacaatcaa acatccacac ctcattgatt tcatctaata gctttagcac
    43441 taagcttgaa acgttgcgat gcttggctgg ctgcccagct ccagtaccta aaaattgtaa
    43501 ttccatacag tctattcttt ctaatgcaca aggtaaatca tgaattctct ttgtgcaaac
    43561 tgataatatt tctttccttt gaatgcttgg ctaagagcca acaattcatc actattaaag
    43621 ccctttagca gggtcatttc gtttgagaaa cgatagatcg tggttaacaa agcatgctca
    43681 ggtgttatgt cctctggctc tccttgctca aattggcagc tcttcatctt gattctacca
    43741 tcttccacat aaaccacgta ttgtggaaaa atctgagcca gctccagcag cagcgattcc
    43801 tcaggctgcc cctgctcttt ttcagcaaaa acaatcgcct cctgtgcttc attttcaaag
    43861 acaaagccat aggattgccc caacaaattt aagcggacaa agggcttcac ctcatcaaat
    43921 gacggctctg aggtaaacag cttcaaggcc cttgatagct caaaataata atctgtcgct
    43981 gcttttggtg attgcttctg atacatttct gcaaaataag cattaatcac acttgggggt
    44041 ggcgtgatgg tagctaattt ttgctggtct gtcaagccct ttaagcaatt ttgcaaataa
    44101 accgtatcta aactcgtaaa gcctccataa gtctttgcca attgaatata atcagtcata
    44161 aaattcttct aatctccatt tatttttggg agcaatgtag ccagaaatct cttcaatctc
    44221 cttatcaaag ctataaggct ccaataacgc caacctgttg aggtcatagc atttgtaggc
    44281 ttgatcctga cagagcttga tcgaaaatgg ctcaaacatg tcccgaatct gatcaataag
    44341 caactgtctt aagaggctac gactgttttt atcacgtgct gacagcctga catttggaaa
    44401 aacagttgca gtcaagctag ctgtcttatc catcttgtta taaatagcca gccttggaat
    44461 atccagcata tctaaatctt tcaagatgtc tagaacaacc ctctcatgct ccaaatgatt
    44521 agggtcactg gcatcaatca catgcaagag caaatcaaca tgccgacttt cctctaatgt
    44581 cgacttaaaa gcagccacga gctccgttgg taaatcttgg ataaagccta cagtatctgt
    44641 cagagttgcc tgaaactgat tttgcagata aatttgcttg gtggtggcat caagtgttgc
    44701 aaataattca tcagcctcat attgcttgtc accagtcaaa atagtcataa tagtagactt
    44761 acctgcattg gtatagccga tcaatccaat attaaagaca tcagaggtca tgcggcgatc
    44821 acgaatcgtt tgacggtttt tttcgacagc agctagctgc cgctcaatat ctgcaatctg
    44881 atgacgaatg gagcgccggt tcagctccag ctggctctca cccggcccac gactcccaat
    44941 gcccccggcc tgacgactaa gcataacacc ctgtccgacc agtcttggca gcatgtattt
    45001 gagctgcgct aaatgcacct gcaattttcc ttcatggctt ctagcccgca tcgcaaaaat
    45061 atcaagaatc agctgcatgc gatcaatgac cttaatacct aaggcgtcct ccaaattggc
    45121 attttgccga gccgttaaac gattgttaac aatcactgta tcaatctcat tggcagcaac
    45181 catttctttg atttcagcca gcttaccaga gccaacaaag gtcttgctat catagcgctc
    45241 cctcttttgc agatagcaat caacgacctc tgcacctgcg gtcttggcta gactagccag
    45301 ctctgtcatt gatagctcag catggtcagc tgcttgtagg accacgctta gtaaaataac
    45361 tctttcctgc cttgcctttg tctctatcat gaacgcgact aatcctccaa attccgtagt
    45421 gtttattata gcatagtttt agctattttc agctagtttg ccatcgatag cttcctaagg
    45481 ctccttcaaa aagcgctcca ccctatcata tattgcctgc ggataggacg actcgctaat
    45541 cgagtcaaag cgcactgcca tacggttacg aaaccaagtc agctgtcgtt tagcaaagcg
    45601 gcgtgtttgc tgctttagtg tggctgttgc ttcttctaaa ctagcctgac cctgaaagta
    45661 agggaagagc tccttataac cgatccctcg actagcctga acagctggat actgctcaaa
    45721 aagccacctt gcctcctcca ataggccaga agccatcatc agatccaccc gcttattaat
    45781 ccgctcataa ataacctctc gctcatcagt caagccaatg atcaaggggt tatagggggc
    45841 ctcttgattt tctaaatccc tagcaaattg atttagctca agtgagcgaa tggcacgcct
    45901 gcggttaacc tgatcaaggt gaatgccctt actagctaat agctgataaa gctctgtatc
    45961 tgtcagtgtc tctagctgct gccgataagc aagtagctcc ttttgatcaa gatctcctcc
    46021 tagatgatag ccctctaaca ggctttgcaa atacaggccg gtaccaccga caataatcgg
    46081 cagtttaccg cggctaacaa tatcttcaat agctcgctta gcgtcctgca caaaatcaaa
    46141 ggctgagtaa gactctgtca cctcacgaat gtcaatcaaa tgatgaaccg caagagcctg
    46201 ctccctggca ctagccttag ctgtcccaat atcaaggtga cgataaacct gctgactatc
    46261 tccagatata atttcaccat taaaggcacc agccaaggca atccctagag ctgtcttgcc
    46321 aacagcagtc gggcctacaa tcacaattat cttttctttt gtcatttatt gtctttctac
    46381 ttaaaaagca gctgaaaaag tcttttactt gaattttcta atctttttcg ctaccatata
    46441 ttataacata agattgagag acagttatgg tcctcttaat agaaatggag aatgattatg
    46501 gctaaaaaac atggattcgc aaagggtctt gctacaggtg ttcttgctac tgctgctacc
    46561 gttgcaggtg cagtatttgc tgttaaaaag actattattg accctgagga agaaaaagca
    46621 gcatttgtag aggaaaatcg taaaaaagca gcacgtcgtc gtgttgctcg ctaatcacta
    46681 atagatgaaa gattcgacag gctttatcaa tagcctgtcg aattttttat gctgtgagac
    46741 caagcttttt gcttagacac ataaaagaaa cagctcgtca gcgccgcata ctgcctactt
    46801 cattgaccaa caaacagggc aaactaaggc taattttcac tgatatgaca tgtttcgact
    46861 ataaagcggt tttgtgattg attgatcaca atatcaaatt gctggtgata agggtgcaga
    46921 taacgagcat attgagcgcg cctattgaca tgatgaactc cggattgcga cctctaatgc
    46981 tagtatctct accaagccgc ctttggagct ctgtgtcacc atctgtataa aagtaaagcg
    47041 ataagtcaaa caactctggc tctaaaaagg ttgtcgacat gccttcagca ataaggatgg
    47101 gcacattccc cttcaccaaa aaagagggag accaaggggt atcaatactc aaaaaatcca
    47161 gtccttgctt aaacatcatg atgtcacgcc tcagactggc caattcgtgc ctagcagggt
    47221 gacaggctgt tatactacca agtacctcct ctccctgatc agggtagcta atcaaaacag
    47281 cctgactaaa atcattagcg atgatatagg catctgtttc taacaattgg ctttgtccat
    47341 caggcaaaag ctgctgtaag cgcttagcaa aggttgattt accagatgca ccatgaccac
    47401 taattctaat aagcattttc tcacgattgg ctgctgcagt tacaatagct tgaagtagct
    47461 tctccattat ctctcctcat caaataacat tctaataata ggacatcatt ctacatcgaa
    47521 aaacaagccg gtctcccgaa acagcctgac tgacagtaaa aaaagattga agggcaatcc
    47581 aataaggaaa gcttctccaa tctgattaat agtctataat ggcttaatat gagtgccaaa
    47641 tgtcttggtt atattgttca atcgtacggt ccgatgaaaa gaagccagcc ttagcaatat
    47701 tatgcacaac ctttgtcagc cataggtcct gattgtcata atcagccagc atttgttctt
    47761 tgactgcaat gtattcctca aggtcaatca aggtcataaa ccagtcctta gagattaact
    47821 ccttatagag acggtcaaga cgttcctcat taccaagctc taataattct ggactgataa
    47881 taaagttaac tgcttccttg atagctgggt gggcatcata atagtcttta gacacataac
    47941 cacctgtggc ataaagatca ataatggtat ctgaatcctt accaaaggtg tagatattat
    48001 ccataccagc aagctcagcg atttccacat tagccccgtc catagtacca agcgtcaagg
    48061 caccattgag catgaatttc atattaccag tacctgaagc ttcctttgaa gctagagaaa
    48121 tttgctctga aatatcagtt gcaggaatca aatgctctgc tactgtcaca ttgtaatttt
    48181 caacaaggtg aacattaagg tatggactta cctccggatc gttattgata agctctgaca
    48241 agcaaagaat caaatgaata atatcctgtg caatgatata agccggtgca gccttaccac
    48301 caaagataac tgttatttta cgcttcggca ggttgccttt tttgatctct aagtatttat
    48361 gaatcacata aagggcattc atctgctggc gcttatattc gtggaagcgt ttaatttggg
    48421 tatcaatgat tgaatgctca tcaagctcaa ttcccttatt atccttgagg tagcgcttta
    48481 aggctacttt attatggtgc ttaatttcag ccaatcttgc atgaacagct tgatcctcag
    48541 caaaggccat taatttttca agccttgtcg catcagtcaa gtaagcatca ccgataagct
    48601 ctttaatata gtccgccaac tcttggttgg cgaattctag ccaacgacgg aaggtaatac
    48661 cattggtttt gttgttgaat ttttctggat acagctcata gaaggccttc aattcgctat
    48721 ttttcaggat ttcagtgtga agggcagcaa cgccgttgac acttgtggca aaatgaatat
    48781 ccatatgtgc catatgcacg cgacctgttt catcaatgat ttggacagct ggatctgata
    48841 cccttgcacg aacaagagca tctaattgct cgataatcgt taccagctgc ggcacaacct
    48901 cattaaggaa gtcaagaggc catttttcca aggcttctgc aaggatcgtg tgattggtgt
    48961 aaccatccat cttttgaacc actgaaacag cctcatcaaa atcaaagcca tgcttttgtg
    49021 tcaatagacg aatcaattct ggaatgacca ttgatggatg ggtatcattg atctgcacgt
    49081 atgcgtaatc agctaagtca tgcaggtttg agccacgctc aagcgcttca tcgatcaaga
    49141 gctgagcggc attagatacc atgaaatatt gctggtaaat gcgaaggagc tcaccatttt
    49201 tatcagaatc atcagggtaa aggaacaggg tcaggttttt ggcaatgtca gtcttatcaa
    49261 atgaaatgcc atctttaatc aagccataat caaccccttc aatatcaaaa aggttaagat
    49321 agttcttggt gtcacgctta tagcccaaaa catcaatacg gtctaagcga gatttcaggg
    49381 taaagttttt aaagggaaca tcatatgaaa tgtcagtcgg tactagccaa gagtcatcct
    49441 ctatccaaaa attaggctct gctgtttgtt cattgtgtct aaagacctgc ttgaacaagc
    49501 cacaatgata attcaagcca accccttcac cattaatgcc aaggcttgag atagaatcaa
    49561 taaagcaaga agccaaacga ccaagaccac cattaccaag cgatggctcc aattcaacgt
    49621 cctctacctc agcaattgat ttgcccgcag cagccagctc ctctttgatg tccttataaa
    49681 tacctagatt aatgagatta ttagaaagca acttaccaat caaaaattct gctgagatgt
    49741 aataaacctt acgtttagct gtgttttttg cttttttgct tgcttcttct ttgagatagg
    49801 aaagcaacga aagatagatt tcctcgttgc ttgcacttgc aagagatttt cctaatgtca
    49861 tttcagtata atctgtaaag cgtttcatga tatcctcttt tcaatatagt attctagtga
    49921 tgattattgg ctcgaccgta tagctcagtc aaatggatta aataggcctt gtgctctgct
    49981 ttaatatcgt cctcaagcat gcgccactgc cagttgccac cgacagtgtt tggcatattc
    50041 atgcggctat cagctgactt atccagcaaa tcctgcatac acaggatagc agtatcacac
    50101 acagtcgcaa agattgttct tagcatggcc ttggtgatgc tttcagcagc tgccttatgg
    50161 atataatgat taacaaactc aacctgctct gcgctcaagt gctcatacca gccattcacc
    50221 acctcattgt catgcgtacc agtgtagaca atgcaattgt gatcatagtt atgcggcaaa
    50281 tcaaagcttt gacttgtcac atcaaacaaa ccaaactcta aaatcttcat gcccggaaag
    50341 ccagtagatg ccagcagctg ctcagccttt tcatcaatgt agccaaggtt ttctgcgata
    50401 attggcagct cacccaaggc ctctcgaaca gctttaaata gagcaatacc aggagctgac
    50461 tcccaatgac catttttagc agtcacatca ccaccaggaa tttcccaaaa atctgagaag
    50521 cccttgaaat ggtcaattct aagcttatcg tacagcttga agctctcttt gatccgatgg
    50581 atccaccaag caaagcctgt ttgctcatgg ctctcccagt tgtaaatagg attgccccaa
    50641 agctgcccgt cctcactaaa gccatcagca ggtacacctg caatgtaaat cggcttttta
    50701 tctgcatcca ccttaaagag ctctggcatc gtccaaacct caacgctatc agcagacacg
    50761 tagattggca tatcaccaat gatagtaatg ccattttgat tagcataggt cttcagcgct
    50821 agccactgct gataaaagaa atattggcag accttatgat aggtgatgcc tttggccaac
    50881 agcttgcggt aatgaagcaa ggcagcctct tcacgcttaa caattgctct atcgtcccat
    50941 tcctggaggg ccttgtgatc aaaatgctct ttaatagcca taaattcagc aaaatcattt
    51001 agccagctcg cagttgcttc aaattcggcg agctgtctta agccttcctc agttgagaca
    51061 aaagcctgaa ctgctttttc taataaaggg cgtctggctt gaaagacttg agcgtaatca
    51121 acagactccg gatttgagcc aaaatcaaca gcagcataat cagcttcctg caaataaccg
    51181 tcctttgcca gcaattcaag gtcaataaaa tgcgtatttc ctgcaatagc tgaaaaagat
    51241 tgataaggag aatctccaaa gctagttgtt gttaagggca aaatctgcca ataggtctgc
    51301 ttggtttcct ttaaaaagtc aacaaattca aaggcctctt taccaaagct cccaataccg
    51361 aagcgtcccg gaagcgagct gatatgcatc agaataccac ttgcacgttt agtcattctt
    51421 tttttctcct tgtaaaatct taatgttgaa attataacgc aaccgtttgc gcaagtcaat
    51481 atcttttcaa aaaaaaagag actttttcgg catgctagag ctgctcaagc cttgataata
    51541 atgagggaag cagctaggac aaaaacaaaa aaaggattgg agagacagcc taagcagctg
    51601 ctcttccatc ctcatctcac tcctatttgg cattaatatc cctgacactc tctcgctttt
    51661 tgaggctaaa gggaaccaaa attttctgac tcagggtttg ttcattggca ttgataatgt
    51721 ctaagagctg cctaaaggag gttcttccca aattttcaac gttaatatca aatgttgtta
    51781 agtaagggtg aatcaatttc gaatagctag aattattaaa ggtaataatc gaaatatcat
    51841 ctggcacctt aatgtcataa aaggacaaga gctggaccat tcgcaccgac aaaacatcac
    51901 caatcacgat taaggctgtg gccttaaagc tacgtatcgt ttcaataacc ttttcgatgc
    51961 ttattggatc ctttcgatca aataacagca tcggtttgtt ttccaaggat aatttcaagc
    52021 agcccttgag atagccaata tagcgctcag aagctacctc tgcctccata tcgtctgtga
    52081 taaacaggat ctgtcggtga cccttttgat agagatgatc aactgcggtt ttagccatta
    52141 gctggttgtc attgtcaata taggtgattt tgttctcatc accttctggt gcgccaacaa
    52201 tgacaaaagg aatctggttg gtcatcaaat agcctctaac aggatcttct tgctcagaat
    52261 ataatataat aaagccatca acacgctttt gcaggtgcat taacttaacc tggctcaata
    52321 aatcctcaac agacatacct gttgcaatgg aaacagtgaa atgatgtttc ttagcttcat
    52381 tggtaatggt cgatagaatt tccataaaaa agggatcact caaacgatca ttagtgataa
    52441 tcggcggaaa aaccaggcca atattatgtg tcaggccact agcaagcatt tgcgcagcta
    52501 cattcggaac atagccaagc tcgctcatag ctcttctaac cttttccttt gtcttttggg
    52561 agatagatcg attatccttg aggacacgac tgacggtcga aggattaaca cctgctttta
    52621 aggcaacgtc ttttattgta accatataaa cctcatttaa tacctgataa tgacgctatg
    52681 tcaggctttt tcacatgtat tttgctttta ttatacaatt atctcctaaa aaatcaactc
    52741 tcgccctgca agaaggcgac ataaaaaact gctgtcctca tgatcgaaaa aatgttaaaa
    52801 aaatcaactt tttttaaaaa aagactagac tttttctgta aacggttgca taatattaag
    52861 tgtaagaaat atatcttagg aggaaatcgc tatgaaatca tggcaaaaag ttatcgtcag
    52921 tggggcaagc ttgacacttg ctagcgcctt attagtaggg tgtgcatctg gttcaaagga
    52981 caaaacagaa actgcatcag gtactgattc aaaaacaatt aagctttggg taccaacagg
    53041 agctaaaaag tcatacacag atgttgtcgc taaatttgaa aaggactctg gctacaaggt
    53101 taaggtgatc gagtcagagg atccaaaagc acaagaaaaa atcaaaaaag atgcttctac
    53161 tgctgccgat gtcttttcac ttcctcatga ccagcttggt cagctcgtag aatctggcat
    53221 tatccaagaa gtcccagagg aatacactaa agagatcgct gatacagcaa ctgatcaagc
    53281 tatccttggt gctcaataca agggtaaaac ctatgccttc ccatttggta ttgagtcaca
    53341 ggttctcttc tacaacaaaa ctaagctagc tgctgatgat gttgcttcat acgataccat
    53401 cacgtctaag gctaccttcg gtggtacctt caagcaggct aatgcttatg ctactggtcc
    53461 attgttcatg tctgttggta acacattatt tggtgaaagc ggtgaagaca ctaaaggaac
    53521 taactggggc aatgaaaaag gggttgctgt tcttaaatgg atttcagacc aagcctcaaa
    53581 caaaggattt gttaacttag atgccaacaa cgtcatgtct cagtttggag acggttcagt
    53641 tgcttcattt gaatcaggtc cttgggatta cgaggcagca caaaaggcta tcggtaaaga
    53701 aaaccttggt gttgctgttt atccaaaggt aactatcggt ggcgaaaccg ttcaacaaaa
    53761 ggccttcttg ggagtgaagc tctatgcggt taaccaagct cctgctaagg gagataccaa
    53821 gcgtatcgca gccagctaca agcttgcttc atacctaaca aatgctgaaa gccaagaaaa
    53881 ccaattcaag acacgtaaca tcgtaccagc taacaagacc gttcaagctt cagaggctgt
    53941 tcaatcaaac gagcttgcaa aaacagttat cacaatggga tcttcttcag attatactgt
    54001 tgttatgcct aagcttagtc aaatgggtac cttctggact gaaagtgctg caatccttag
    54061 cgatgccttc aatggtaaaa tcaaagaagg tgactacctt gctaagctac agcagtttga
    54121 caaggacatt gcagcaacaa aataagctat ctcatttata atactatcct aaacaagtac
    54181 agaggtgggc tattttaacg ctatcctttc tactcatctc taaaggggtg gaactaagca
    54241 tcattatttt ttcagggctt agtccactcc tacttgtttt tgatatgacg taaagcttgg
    54301 tgctacttaa atttttaatc gcttaaagat ttaggtaaca cttagctatg tggtcgttag
    54361 caccaaacgc ttatgaccac agcatctgaa caagagagtc aggtaatcct actttcttgt
    54421 atcctaacat aaaggagaac atatatgact caggcaggct tagcatctca ggttactgta
    54481 aaagaggctt taacaaaggg aagcttcgat attaaactat ccgctatcat catgggcttt
    54541 gccaattttg ctaataaaca attcgtcaaa ggaacactct ttttattgag tgaggtggtc
    54601 tttttcatcg cctttgtttc acaaatcatt cctgctattg gcggcctcat taccctagga
    54661 acacaaacac agggcatgac aaccaaaact atcgacggta tcagcattca ggttgctgtt
    54721 gatggagaca attcgatgct aatgctgatt tttggcttag cctctctgat tttttgtttg
    54781 ttatttgcct atatttattg gtgtaaccta aaaagcgccc gtcacctcta catgctaaag
    54841 caagaagggg caaaaatccc aagctttaag gaggattttg ttagtctagc aaatggtcgt
    54901 ttccatatga ccttgatgac aattccattg attggtgtgc ttctgtttac ggtacttcct
    54961 ttgatctaca tgatttgctt agcatttact aactttgatc acaatcacct cccgccaaag
    55021 tcactttttg attgggttgg tctttccaat tttggtaacg tgttaagtgg tcgtatggca
    55081 ggaaccttct ttcctgtttt ctcatggaca ctgatttggg ctgtctttgc cacagtgact
    55141 aacttcttct ttggtatcat tttagcactc ttgattaata ccaaaggctt aaaattgaaa
    55201 aaaatgtggc ggaccttctt tgtgattacc atcgcagttc ctcagtttat ttcactgctg
    55261 attatgcgaa atctgctaaa tgaccaaggt cccttaaatg ccctgcttag caaattaggg
    55321 ttaatccacc attctctacc gtttttatct gatccaattt gggctaaatt ctctattatt
    55381 tttgttaata tgtggatcgg tattccattt accatgttaa tcgcaacagg tatcattatg
    55441 aacctgccaa gcgaacaaat tgaggctgca gagattgatg gggcaagtaa attccaggtc
    55501 ttcaaatcaa tcaccttccc tcaaatcctc attatcatga caccaaacct gattcagcaa
    55561 tttattggaa acatcaataa cttcaatgtg atctatctct taactggtgg tgggccaacc
    55621 aattcagcct attaccaagc tggaaccacc gatctattgg tgacttggct ctataaattg
    55681 actgttacag cagcagatta taatctagcc tctgttattg gtatcttaat ctttaccgta
    55741 tcagcaatct ttagcttact ggcttacaca agaactgcat catacaagga aggagcagcg
    55801 aaataatgaa aaacaaacgt cgatttcagc ttggattagt ttacgccatt ttaaccgttc
    55861 tctcaatcat ttggctttta cctatcgctt gggttgttct gactagcttt cgtgctgaag
    55921 gcactgctta tgtcgattat tttcttccca agcacctcac attagaccat tatattaagc
    55981 tctttacaaa tgaaacattt ccttttggga gatggtttgt caataccttt gttgttgcta
    56041 tctttacctg tatcatctca acctttatta cagtggcgat ggcttactcg cttagtcgga
    56101 tcaaattcaa gtttcgcaat cgtttcttaa agcttgcact agtgctaaac atgtttccag
    56161 gctttatgag catgattgct atctactata tcctaaaagc acttggcctt acgcaaagtc
    56221 ttaccgccct agtccttgtt tattctgccg gtgctgcact tggattttac attgctaagg
    56281 gcttctttga taccattcct tattcgcttg acgaatctgc catgattgat ggggctactc
    56341 gtatggatat tttctttaag attaccctac cgctatcaaa gccaatcatt gtttacactg
    56401 cactccttgc ctttatggga ccttgggttg actttatctt tgcccaagtg attttaggag
    56461 atgcaaccag cagatatacg gtagctatcg gactcttttc aatgctgcag cctgacacca
    56521 tcaatgactg gttcatggcc tttaccgctg gatctgtgtt aattgctatt ccaatcacat
    56581 tgctctttat gtttatgcaa aaatactatg tagagggcgt tacaggtggt tctgtcaaat
    56641 agcagtaatg atcacgataa cccttactca aaaaatcctt ccc
//
LOCUS       DARYMD010000006        51658 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYMD010000006 DARYMD010000000
VERSION     DARYMD010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51658
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..242
                     /locus_tag="TU818_000314"
     CDS             <1..242
                     /locus_tag="TU818_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0923175.1"
                     /translation="NYKKNSISKEEYLRKKILVQDRKKLLENKIKELENVEDDSKKEL
                     DINNLDEDNLLKIYVDNIIDKIIASRTGEIEIIEK"
     gene            283..897
                     /locus_tag="TU818_000315"
                     /pseudo
     CDS             283..897
                     /locus_tag="TU818_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1427..2305
                     /gene="mvk"
                     /locus_tag="TU818_000316"
     CDS             1427..2305
                     /gene="mvk"
                     /locus_tag="TU818_000316"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL0923176.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIMSQVPQKRGMGSSAAVSIAAVRA
                     VFSYFGQPLSDELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCFTEAVEQAIKTNDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVAAALEAGALGAKMTGGGLGGCMIALAERITDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            2287..3231
                     /gene="mvaD"
                     /locus_tag="TU818_000317"
     CDS             2287..3231
                     /gene="mvaD"
                     /locus_tag="TU818_000317"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL0923177.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEAKMIPSTSSISLTLEGMYT
                     TTSLSFLPASAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQTFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGWLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQEGYSCYFTMD
                     AGPNVKVLCLEEDLERLSHLFEREYRIIASKTKELPDV"
     gene            3224..4222
                     /locus_tag="TU818_000318"
     CDS             3224..4222
                     /locus_tag="TU818_000318"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL0923178.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYIDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVVLTLRALAAFYQVQLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRRKVGQWLIEMTLKELMAAHWGYTIETIEPALPCWFLVGWTQVPSISREM
                     IQLVNKSISCQFLEQSQLVTQEVMTALQLGQRKRLKASIEKAGQLLQGLASVIYHPKL
                     TQLVQACQGLDAAAKSSGSGGGDCGIALVFEAKDIEPILARWQQAGIVLLYQEEWG"
     gene            4225..5217
                     /locus_tag="TU818_000319"
     CDS             4225..5217
                     /locus_tag="TU818_000319"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL0923179.1"
                     /translation="MTNRKDDHITHALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVV
                     LELVETYPVEQIIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(5502..6785)
                     /locus_tag="TU818_000320"
     CDS             complement(5502..6785)
                     /locus_tag="TU818_000320"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL0923180.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDVANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSAKCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARTGSYRGLSSWHVDLSKNSLCGELTLPMPIASKGGSIGLNPT
                     VSVAHSLLEQPNAKVLAQITTAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAGQLLTAIRLSQS"
     gene            complement(6772..7947)
                     /locus_tag="TU818_000321"
     CDS             complement(6772..7947)
                     /locus_tag="TU818_000321"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL0923181.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAVCFHIPFPKLALKGLHKIMTKSLADDHKERLYENFQASIAYSKQIGN
                     IYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQA
                     LLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN"
     gene            8132..8971
                     /locus_tag="TU818_000322"
     CDS             8132..8971
                     /locus_tag="TU818_000322"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL0923182.1"
                     /translation="MTKADHIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRSIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWKAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACQPKLLLHVPDGTDFFDIRPEDFELQDYYPVKPQLTFD
                     LAI"
     gene            9052..9549
                     /locus_tag="TU818_000323"
     CDS             9052..9549
                     /locus_tag="TU818_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL0923183.1"
                     /translation="MTKKIIAIWAEDEAGLIGACGRLPWYLPKELQHFKETTLNQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTRDSYYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGYFDVIIKTVVHHQFEGDTYRPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            9569..9739
                     /locus_tag="TU818_000324"
     CDS             9569..9739
                     /locus_tag="TU818_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923184.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            9775..11004
                     /gene="clpX"
                     /locus_tag="TU818_000325"
     CDS             9775..11004
                     /gene="clpX"
                     /locus_tag="TU818_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL0923185.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLEILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMVQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVR
                     ITKEAVEGQSKPILEIA"
     gene            11014..11613
                     /locus_tag="TU818_000326"
     CDS             11014..11613
                     /locus_tag="TU818_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL0923186.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHESSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            11977..14979
                     /locus_tag="TU818_000327"
     CDS             11977..14979
                     /locus_tag="TU818_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL0923187.1"
                     /translation="MTIKKCPQILALFLAFAALASQGQTVHALERQETSVKQAHESDD
                     WFDEDEGVSDIKSNTPTEIDSTVTELFGDAEPKTKAEKEESKAPSPKQEALPAESQKE
                     KETSAKSTDHATVQAEEAQPEQGSDSPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLV
                     LPRIGIDKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRDILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERVFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHAVLRTKNGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNRWLAEDFTYTGQTITGFSASGLRKVKRNKHLVLPKNYQGQPLTAIADNA
                     FRNVNFHDKTLRKYDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN
                     RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVMFMGDKLIS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFKINRLQ
                     RVTVPDTVISISFNAFDHNSDDKVVLRTTNHNKNLLADGNGFIVDPDLLSADQSTVQA
                     VLEDLRRLDLASLRADTAAHFMTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKTADITLSSHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKVSRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKLLPKTGAF
                     KEAWVTMIGMLVLLAATLLKGDSRYKKK"
     gene            complement(15169..17262)
                     /locus_tag="TU818_000328"
     CDS             complement(15169..17262)
                     /locus_tag="TU818_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL0923188.1"
                     /translation="MATYYGKDPFENMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAAAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEITK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGASDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDRADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLTEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            17633..18052
                     /gene="ndk"
                     /locus_tag="TU818_000329"
     CDS             17633..18052
                     /gene="ndk"
                     /locus_tag="TU818_000329"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL0923189.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDTLINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            18553..19359
                     /locus_tag="TU818_000330"
     CDS             18553..19359
                     /locus_tag="TU818_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0923190.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVVDTPVLNQSEKAVY
                     ANDFGSGNRASDYVPAANAWSFEAYPDYYSILGASHLNPAVFPEPSKMSYSPLDELGR
                     TQVARGTITYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     VPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTIDYATGAFRSN"
     gene            complement(19651..20616)
                     /locus_tag="TU818_000331"
     CDS             complement(19651..20616)
                     /locus_tag="TU818_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL0923191.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKATNKEASHTNSQQQKGAVSWTKQQNPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKYDIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            20788..22071
                     /locus_tag="TU818_000332"
     CDS             20788..22071
                     /locus_tag="TU818_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL0923192.1"
                     /translation="MSVKVALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DETTKKRLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGELSTLAAKHQVALYYEAAVAGGIPILRALADSFASDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYERALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGMT
                     IDFEAISYSGIDKVRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIMSPYYFAIQATNKFGQLLELTRLCDVCGIRVEQLLSDEIDSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            22073..22933
                     /locus_tag="TU818_000333"
     CDS             22073..22933
                     /locus_tag="TU818_000333"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL0923193.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTDDRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNKKKMAIYEAIEQLGLIGQLVSL
                     ELDRQGLCLV"
     gene            23098..24357
                     /locus_tag="TU818_000334"
     CDS             23098..24357
                     /locus_tag="TU818_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL0923194.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIRGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANCI
                     RPLTDRLISETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFHYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            24357..24980
                     /gene="folE"
                     /locus_tag="TU818_000335"
     CDS             24357..24980
                     /gene="folE"
                     /locus_tag="TU818_000335"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL0923195.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSKRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            24988..25788
                     /gene="folP"
                     /locus_tag="TU818_000336"
     CDS             24988..25788
                     /gene="folP"
                     /locus_tag="TU818_000336"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL0923196.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLAAEYDVPIILMHNQTKEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLNEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            25795..26154
                     /gene="folB"
                     /locus_tag="TU818_000337"
     CDS             25795..26154
                     /gene="folB"
                     /locus_tag="TU818_000337"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL0923197.1"
                     /translation="MDKIRLEACRFYGYHGAFKEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFAQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            26151..26657
                     /gene="folK"
                     /locus_tag="TU818_000338"
     CDS             26151..26657
                     /gene="folK"
                     /locus_tag="TU818_000338"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL0923198.1"
                     /translation="MTLVYLGLGTNMGDRAGYLQAAVNALSKLPETELLRQSSIYQTA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DEPYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            26753..27640
                     /gene="murB"
                     /locus_tag="TU818_000339"
     CDS             26753..27640
                     /gene="murB"
                     /locus_tag="TU818_000339"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL0923199.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIRTV
                     EQASGVRLEPEVRIIGESL"
     gene            27686..28840
                     /locus_tag="TU818_000340"
     CDS             27686..28840
                     /locus_tag="TU818_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923200.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGERINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHADGLINAIEEERNEENL"
     gene            28824..29618
                     /locus_tag="TU818_000341"
     CDS             28824..29618
                     /locus_tag="TU818_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923201.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            29615..30391
                     /locus_tag="TU818_000342"
     CDS             29615..30391
                     /locus_tag="TU818_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923202.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            30384..31457
                     /locus_tag="TU818_000343"
     CDS             30384..31457
                     /locus_tag="TU818_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0923203.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYQNSIMLVDGAREILGVGLTTFGYSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEN
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDIKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            31615..33147
                     /locus_tag="TU818_000344"
     CDS             31615..33147
                     /locus_tag="TU818_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL0923204.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMVS
                     EAVVGYYHQAHSNRMLLVPIAGFSLLAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWWSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALHQYWLLLILGLVLGCLGFLYEEVILHFHRVYDFLGKSLRLAPHFHGLI
                     VVAIILLIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLILQQIGLLDRQMIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLKLPKNVLITTQLHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            33353..33967
                     /locus_tag="TU818_000345"
     CDS             33353..33967
                     /locus_tag="TU818_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL0923205.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRAIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            34315..35442
                     /locus_tag="TU818_000346"
     CDS             34315..35442
                     /locus_tag="TU818_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL0923206.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKARRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKAIH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQSS"
     gene            35594..36271
                     /gene="radC"
                     /locus_tag="TU818_000347"
     CDS             35594..36271
                     /gene="radC"
                     /locus_tag="TU818_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL0923207.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQEQLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(36273..36968)
                     /locus_tag="TU818_000348"
     CDS             complement(36273..36968)
                     /locus_tag="TU818_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL0923208.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTSFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDIFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQEIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGTIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(36980..37624)
                     /locus_tag="TU818_000349"
     CDS             complement(36980..37624)
                     /locus_tag="TU818_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL0923209.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(37910..38257)
                     /locus_tag="TU818_000350"
     CDS             complement(37910..38257)
                     /locus_tag="TU818_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL0923210.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(38247..39374)
                     /locus_tag="TU818_000351"
     CDS             complement(38247..39374)
                     /locus_tag="TU818_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL0923211.1"
                     /translation="MIYFDNAATTSLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGAAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEAKNGIIDLNQLQAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLA
                     PLLHGGNQENKQRAGTESLINIVGMTQALDEAVSRLPQHYQHAKELSQLLLSELEGIS
                     YQLNHNECHLPYIINIGFPGYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRVSFSEQNTQKDVIALATQLKNILGGSYGI"
     gene            complement(39377..40351)
                     /locus_tag="TU818_000352"
     CDS             complement(39377..40351)
                     /locus_tag="TU818_000352"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL0923212.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILECAGATDIYAVASHGIFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(40486..41058)
                     /locus_tag="TU818_000353"
     CDS             complement(40486..41058)
                     /locus_tag="TU818_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL0923213.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDVDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVRGKV
                     DFDHFLAQHQITFKYSKSKVARFSKTLKKS"
     gene            41153..41824
                     /locus_tag="TU818_000354"
     CDS             41153..41824
                     /locus_tag="TU818_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL0923214.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            41799..42635
                     /locus_tag="TU818_000355"
     CDS             41799..42635
                     /locus_tag="TU818_000355"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL0923215.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPSFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDS
                     ES"
     gene            42632..43534
                     /locus_tag="TU818_000356"
     CDS             42632..43534
                     /locus_tag="TU818_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL0923216.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEESFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDITLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKDRG"
     gene            43538..44539
                     /gene="pta"
                     /locus_tag="TU818_000357"
     CDS             43538..44539
                     /gene="pta"
                     /locus_tag="TU818_000357"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL0923217.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFAEQHYTIINPNDYADFEKMKAAFVELRKVKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENESIN"
     gene            44639..45397
                     /locus_tag="TU818_000358"
     CDS             44639..45397
                     /locus_tag="TU818_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL0923218.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSEPTAIDKALAELPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMINTNIIGLIYLTRQVLPQMVSSNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLAGTNIRVTNIEPGLCEGTEFSHVRFKGDHERVKALYAGAHAIQPRDIANT
                     VSWIIDQPEHVNINRVEMMPVSQSYGSQPVSRHD"
     gene            complement(45502..46188)
                     /locus_tag="TU818_000359"
     CDS             complement(45502..46188)
                     /locus_tag="TU818_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL0923219.1"
                     /translation="MTKTIYTLALVDDKNNLQKTFFTTLSQEFSYLFHITIVRQLTTE
                     QLKKAQAIFTFQNLEASLPVLYFNQADKEQGFTVSDHTFTDSQQTLRLAKYLMQFYQA
                     LAPHFLTYLPLQARIADHQGQIIFDNHRFNGNFFASDKHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDTKQFVGVYDMILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
     gene            46443..47171
                     /locus_tag="TU818_000360"
                     /pseudo
     CDS             46443..47171
                     /locus_tag="TU818_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            47164..48696
                     /locus_tag="TU818_000361"
                     /pseudo
     CDS             47164..48696
                     /locus_tag="TU818_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
     gene            49054..50037
                     /gene="guaC"
                     /locus_tag="TU818_000362"
     CDS             49054..50037
                     /gene="guaC"
                     /locus_tag="TU818_000362"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL0923220.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            50223..50804
                     /locus_tag="TU818_000363"
     CDS             50223..50804
                     /locus_tag="TU818_000363"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL0923221.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIHQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGIVSFLEADA"
     gene            complement(51092..>51658)
                     /locus_tag="TU818_000364"
     CDS             complement(51092..>51658)
                     /locus_tag="TU818_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL0923222.1"
                     /translation="LDQSLGSIFLKEKGMSIDLGALAKGYIADKLMAFLIKDGITAAL
                     INLGGNVLVHGTNKQRHNGLFYVGIQQTNQKRGQHVGVIKVNNKSVVTSGIGERQLQI
                     KDKTYHHLLDPHNGYPIKTNMASLTIVSQFSLDGELWSSRLFGLEHSFVLSQLNKLPE
                     VEGIIITKDGQVTISDGLKGAFRLHYKH"
BASE COUNT        14628 a         9764 c        11834 g        15432 t
ORIGIN      
        1 agaattacaa gaaaaatagt atttcaaaag aagaatattt acgaaaaaaa attcttgttc
       61 aagacagaaa gaagttactg gaaaacaaga taaaagaatt agaaaatgta gaagatgatt
      121 ccaagaaaga actggatatt aataacttag atgaagataa tttgttgaaa atatatgtag
      181 ataatataat tgataaaata attgcatcaa gaactggaga aatagagatt atagagaaat
      241 agataattca ggaaattcta tatcaattgc ttgacattgt agggaaagtc ctctatcatg
      301 aatttgctgt atcgctttta tgatgtacaa tcaggcctca ttacagttga tgggcaaaat
      361 attcaggagt attctagaga aagcctgcgt tcacagatgg gtattgtctt gcaggatcct
      421 tatttgttta caggaacgat tgcttctaat atcacgatgg gaaatccagc ttattcggat
      481 caggatattt tagatgcttt ggaaaaggtc ggagcctctt cgatgattgc tcgtctggaa
      541 aagggcattc atgagcctgt ctatgaaaaa ggctcctctt attcaagtgg cgagcggcag
      601 ctaattgctt ttgctaggac attgattgcc gaccctaaaa ttttgatctt agatgaagcg
      661 acctcgcaca ttgatactga gacagaggac atcattcaac aggctatgga ggtcttaaag
      721 aaaggccgaa caacctttat cattgcccat cgcttgtcta ccattcaatc tgctaatcaa
      781 attttagtat tggataaggg gaggatcgtc gaaagaggaa cacatcagga attgctagat
      841 cagcaaggca tttatgctga aatgtccaag ctacaagaaa aggtggctgt acagtaatgc
      901 tttttagtga tagctatcaa aaaattcctt ttctaggccg tgttaagcag cagtagtctg
      961 tgaagtagga gctatattta ggttttgtgc ctaagccttt aaggttttta agaggctgga
     1021 ttagggctta acatcaataa aatcatatgt cactttatca cagcatgttg tggtgaagtg
     1081 ttttttgtgt cgtcctgcta aagggaagat cctcacagtc agggcttggc tggctccttt
     1141 atcagagtca gatcattcat acgtacttcc tgtcaggctt ggctaagttg aattgtatgt
     1201 tgagatcagc atgtcagcaa tttatgcttt gtgtctgact tttagcagct tgtacatgaa
     1261 ataggactaa aggacacttg aattgatgaa gaatcagctt aaaaaccatt tgtcctagat
     1321 aggataagaa ctgtctaaaa gggggataga tcatcgcaat ttttaacaat ttagtgtaaa
     1381 atagtaaggt gaatgttttg atgaaataaa cgaaaagatt taggatatga ataagacaat
     1441 tggatatggc aaggcacaca gcaaaatcat tttaatgggt gagcattctg tggtctatgg
     1501 ctaccctgcg ttggccttgc ccttaaaaga tattgaagtg acctgccgga ttttccctgc
     1561 tgcaaagccc ttagcctttg atttttatga tcccttatca acggcagttt atgcagcctt
     1621 ggagcatttg gggtgcttgg cagagcccat tcattatgat attatgtctc aggtaccaca
     1681 aaagcggggc atgggctcct cagcagctgt ttcgattgca gctgttcgag ctgttttttc
     1741 ttattttggg cagcccttgt cagatgagct gttggaaatc ttggtgaata aggcagaaat
     1801 cattgctcac accaatccca gtggcctaga tgctaagacc tgcctcagtg ataaggccat
     1861 caaatttatt agaaatgttg gttttgatac cattgatatt cagttaaatg cttatttggt
     1921 cattgctgat acagggattc aggggcatac gcgtgaggct gtcaataagg tggctcaatt
     1981 tgaggaggaa aatcttcctc atttagccaa gcttggctgt ttcacagagg ctgttgagca
     2041 agcaattaag acaaacgatt gcctagctat tggacgattc atgacgcagg cacatgaatc
     2101 actaaaggct attggtgtca gtgtggcaaa ggctgatcag ctggttgcag cagctcttga
     2161 ggctggcgct ttaggagcta aaatgactgg tggtggctta ggaggatgta tgattgcatt
     2221 agctgaaagg ataacagacg ctcagcaaat cagtaagaaa ctaaaagaag agggagctgt
     2281 aaatacgtgg attcaaatac tgtaacggta acttcctacg ctaatattgc tattgtcaaa
     2341 tactggggga aaaaagatga ggctaagatg atcccatcaa cctctagtat ttctttgacc
     2401 ttggaaggca tgtacacgac aacaagtctt tcttttttgc ctgcctcagc aaagggagat
     2461 cagttttata tcaatggtgt tctgcaggac gccaaggagc atgctaagat tactgcgatt
     2521 ttggatcagt tccgtcagaa ggaccagact tttgtcaagg ttgaagccag caacagcatg
     2581 ccaactgcgg caggcttatc ctcaagctct agtggcttat ctgctctggt aaaggcctgc
     2641 aatcagcttt ttcaagctaa gctaagtcaa gaagagcttg cccaaaaggc taagtttgcc
     2701 tctggctctg cttcgcgttc tttttttggc cctgttgctg cctgggataa ggatacaggc
     2761 tctatttata aggtcaaaac agatttaaag ctggccatga ttatgctggt cttgaacgat
     2821 gctagaaagc ccatttcgag tcgagagggg atgaagcgct gcagcacaac ctcaacaagc
     2881 tttgaccagt ggctggccca gtcagaaagt gattatcagg ccatgttgcg tgcccttagt
     2941 gacaatgatt ttgaaacggt tggttggctg acagaagcaa atgctctagc catgcacgca
     3001 acgaccaaaa cagccagtcc ttccttctct tacctaacag aggcctccta tcaggccatg
     3061 ctaagggtca aagagcttcg tcaagagggc tattcttgct attttacgat ggacgctggt
     3121 ccaaatgtca aggtgctttg tttagaagag gacttagagc ggctgtcgca cctttttgaa
     3181 agggagtatc gtatcatcgc ctcaaaaaca aaggaattac cagatgtcta aatatcatgt
     3241 tcaagcagga ggaaagctgt atctgacagg cgaatatgcg attctaaggc cggggcaaac
     3301 ggcgttgatt tgctatattc ccataatgct gacagctgtc attgaagcag cagaggctgt
     3361 tagtatcagc tcagatatgt ttgaccatgc tgctgatttg tcaccggata aggattatag
     3421 gctgattcaa gcctctattg aagcctttag tttatatata gataaggata ttaaggagct
     3481 gccagccttt tctttgtcta ttactggtaa gcttgagcgt gacggtaaaa agtttgggat
     3541 tggctctagc ggtagtgttg ttgtactaac gctaagagct ttggcagcct tttatcaggt
     3601 tcagctgcta ccagagcagc tctttaagct ggctgcttat accctgctta aatcaggaga
     3661 taatggctcc atgggggaca ttgcctgcat tgcctatgag agcttggttg cttatacatc
     3721 ctttgatagg cgtaaggttg gtcaatggtt gatcgagatg accctaaaag agctaatggc
     3781 agcacattgg gggtatacga ttgagactat tgagcctgct ctgccctgtt ggtttcttgt
     3841 tggctggacc caagtccctt ctatctcaag agagatgatt cagctggtta acaagagcat
     3901 tagctgtcag tttttagagc aaagccagct ggtcacacag gaagtgatga ctgccctgca
     3961 gcttggtcaa agaaaaaggc tcaaagctag cattgaaaaa gcgggtcagt tgctgcaagg
     4021 gttggcttca gttatttatc accctaagct tacgcagctt gtccaggctt gtcaagggct
     4081 tgatgctgct gccaaatcat caggctcagg aggtggggat tgtggtattg cactcgtttt
     4141 tgaggctaag gacattgagc ctatccttgc cagatggcag caagcaggga ttgtattact
     4201 atatcaggag gaatggggat aaacatgact aatcgtaagg atgaccatat cacacatgct
     4261 ttgagctatc attctcctta caatgcattt gacgacatgg agctcattca ctgttccttg
     4321 ccgagctatg atttagctga tattgatctc tcaacccatt ttgctggctg tgattttgag
     4381 tttccttttt atatcaatgc gatgacaggt ggtagcaaga aaggccaagc agtcaatgaa
     4441 aagctggcca aagtggctgc ggctacaggt attttaatgg tgacaggctc ttacagtgca
     4501 gccttgaaaa atcctgagga cacttccttt caattgcgag gtgtagcacc agatttacag
     4561 ttggccacca acattggtct tgataaggct gttgacctag ggattagagc tgtcgaggaa
     4621 atgaagccct tgtttttaca ggtacatgtg aatgccatgc aggagctgtt aatgccagag
     4681 ggagagcgca gctttaagca ttggaaggat catttagcgg cctatgccaa gcagcttcca
     4741 gtccctttga ttttaaaaga ggttggcttt ggtatggata ttaagaccat cactatagca
     4801 cgtgatatgg gagtaaaaac ctttgatatt tcaggaagag gaggaacctc ctttgcctac
     4861 atcgaaaatc aaagaggaag taatcgctct tacctagacg attggggaca gacaacagtg
     4921 caatgtctat taaacgccaa aggtctggtt gatgaagtgg agatcttagc ctcaggtggt
     4981 gtcagacacc ccttagatat ggttaaatgc ttggtgctgg gggcacgtgc tgtgggccta
     5041 tcgcgagtgg tattggagtt agttgagacc tatccagttg agcagatcat cgctacgatc
     5101 aatagctgga agaaggagct taagctcatc atgtgtgctt tagattgtcg aaccttgagc
     5161 gatttgcgtc aggtggatta tttattatat ggtaggcttt atcaggcaaa ccgctaaaga
     5221 ctttttagcc ctgagctaac tttccttaga aaatcatcac aggagttaag aagctgcctg
     5281 cttggtgctg caagctaatt cagctgatta tggctcgtaa gatttttaga tgtctgaatg
     5341 aaatgatagg acagatgaca tagtatagcg ctaatttcta gtgaaaatca gtccttggtc
     5401 aggttactga gactgaggtt aagtttatgt ttacactaac acttaaagga tatgaaaaca
     5461 cttggtagct gccactgaag ctgttaccaa gtgtttttag tctatgattg gcttaatcgt
     5521 atggctgtta agagctgtcc tgccttttct aggttcattg gcttatcctt tagtagagcc
     5581 ttaactagtt gaggcacctc ctgctcacta gcacctgcta atagagctag agacttggcc
     5641 tgcagcttca tgtgaccagc ctggatacca gttgaggtca aagcctttag agccgcaaaa
     5701 ttttgcgcca gcccaactgc agtggtgatt tgggcgagaa ccttagcatt tggttgctct
     5761 aaaaggctat gagcaacact gacggttggg ttgagaccga tcgaccctcc tttactagca
     5821 atgggcattg gcagtgttag ctctccgcat aagctatttt tagataaatc aacgtgccag
     5881 ctacttagcc ctctataaga gccagtcctt gcggcatagg catgtgctcc agcctcaata
     5941 gctctccagt catttccggt agctatagct accgcatcga ttccattaaa gattccctta
     6001 ttatgcgttg ctgctcggta agggtcaatc tgggctaatt tgcttgccag ctctattttt
     6061 ttggccaatt gctgagcttc ttccttatgt cgacttaggt atctgaggtc aacctgacat
     6121 ttagcactaa ctaaagcttt tgttgcatag tttgagagga tagccattaa gcattgacca
     6181 ccgcttaggg cctccaaatc aggtactaaa gcctccatca tcgtgttaac gatgttggct
     6241 cccatagcct cttgggtatc aacgctcaga tagacaatga aaaaatcctc cttacgctca
     6301 acggtaaggc tctttgcgcc accaccacgc ttaacaatag aagggtaggc attgtttgca
     6361 acgtcaatca atgtatctgc gttagctaga atagccagcc tagcctgctc gtcatcttta
     6421 acatcataaa gagctacctg cccaagcatt tgacgactga gtacctcagt ctgaaagcca
     6481 cctgatcgct tgatgatttt ggcagcaaag gaagcagcag caacaacaga aggctcttca
     6541 gtcacaaagg ggacctgata ggtatgccca ttgatcagaa aatcaggggc tagactaaaa
     6601 ggcagagcca gtcgaccgat gacattttcg gtcatttgat tggcaatagc aatgggtaag
     6661 agctggtctg tctctaacag cttttgctgc tgcgggccaa gcagctggtc atctgcgagc
     6721 tgttgaatgc gttctgcaag gcttttttta taaaagccgg cccaatttgg tttagttttt
     6781 gtcatcatct tgataaattc gttggtgttc cttaatttct ttgagggcaa acctgccagt
     6841 tagatatggt gaaaagctgg cattgccatc ttggtctagt ctaggctctt cataaaaaag
     6901 tgcttcataa tcagccactg aaatcacctg acgttggtct aatagggctt gtcgattagt
     6961 cagtagcatg tccttgtaac cgtcaacaag ctgccctgaa aacagctcac taacagctcc
     7021 tgagccatag ctaaacaatc caatcctatc accagccctt agcacctgac tattctctaa
     7081 aagtgataat aagccgaggt agagtgagcc tgtgtaaatg ttgccgattt gcttgctgta
     7141 ggcaatagaa gcttgaaagt tttcataaag cctttctttg tgatcatctg ctagtgattt
     7201 tgtcatgatc ttatgaagtc cctttagagc aagctttgga aaggggatat gaaaacaaac
     7261 agcagcaagg tctgatagct caataccttc tttttcttgg tatttgtccc aggttgtttt
     7321 tagggaatca aggtattgct tggtcgaata aataccattg acaaatggtg ttgagctgta
     7381 atttggacgc caaaaatcca tcacatcacg tgtctgtgcg acattgtcat gatttaactg
     7441 gagaatacga ggattagtag taactagcat agcaatactt ccagcacctt gtgttggctc
     7501 tccggcggat ccaatgccgt atttggcgat gtcactggca atgaccaaga ccttggaggc
     7561 tgggtgtgca gcaacatgta atttggcata atctaaagca gcagtagcgc tgtagcaggc
     7621 ttcctttatc tcaaaggagc gtgcaaaggg ctgaatatca agcagctgat gaacgtaaat
     7681 actggctgcc tttgattgat caatgcttga ttcggttgct aaaatgacca tgtcaatgct
     7741 tgctttatcg tctttggtaa ggatttggtc agcagctgat gcagcaagcg ttacaatatc
     7801 ctctgtaaca ggtgcaatgc ttagagcgtc aagcattagc ccctgatgaa attttgctgg
     7861 atcagtgctg cgagcaagtg ccaggtcttc catttttaag acgtattgac tggtcgcaaa
     7921 gccaatctta tcaattccga tgttcataaa tatccttctt ttatccattt tatagtccta
     7981 tccattttat catattttct tagaaaatta gctgatttaa tacgatagtt ttacctttca
     8041 aaccaaaaac agcagcatat agctttcttc tggtattttt gaaggaaatt agataaaata
     8101 atatggactg tgcttacaga aaggggtttc catgacaaaa gcagatcata tttttaaagc
     8161 taatatcaaa aaaattatgg aggagggagt ctttagcgag caggctcgcc caaggtataa
     8221 aaatggtcaa acagccaatt ccaaatacat tacaggtgct tttgcagagt atgatttgtc
     8281 taagggagag tttcctatta caactctaag atcaatccct atcaagtcag ctattaaaga
     8341 gttattttgg atttatcagg accaatcaaa cagccttgat gttttagaaa acaaatacaa
     8401 cgttcactat tggaatgagt gggaggtcgg tcagacaaga accatcggtc agcgctacgg
     8461 tgcaatcgtt aaaaagcatg atatcatctc aaaaatcctc aagcagctag aggacaaccc
     8521 ttggaatcgc cgaaatgtga tttctctgtg ggattacgaa gcctttgaag aatcagaagg
     8581 actgctacca tgtgcctttc aggtgatgtt tgatgttagg cgagtagatg gtgagctgta
     8641 tttagatgcc acgctgaccc agcgctcaaa tgatatgcta gtggctcatc atatcaatgc
     8701 catgcaatat gttgccctgc agctaatgat tgccaagcat tttggctgga aggctggtaa
     8761 gttcttttat tttgtcaata atttgcacat ctatgacaac caatttgcgc aagccaagga
     8821 gctattggag cgtcagccag cagcctgtca gcccaagctt ttgctgcatg ttcctgatgg
     8881 gacagacttt tttgatataa gaccagagga ttttgagcta caggattatt acccagtgaa
     8941 gcctcagctc acctttgact tggcgattta agcgaaaaag acgatttttt ctgagcattt
     9001 tgccaagaaa tttgatagaa taaaagaagt tcatattgag gaaagctagt gatgacaaag
     9061 aagattattg ctatttgggc agaggatgaa gcaggactta tcggagcgtg tggcaggctt
     9121 ccttggtacc taccaaaaga gttgcagcat ttcaaggaaa caacattgaa tcaagctatc
     9181 ctgatgggac gagtaacctt tgagggcatg aagggtcgtt tgctgccaaa tcgccaaacg
     9241 cttgttatga ccagagacag ttattatcat gtggagggcg ctttaaccat aaccagtgtg
     9301 caggaggctt tggattggta tcatgcgcag gataagacct tatatgtgat tggtggcagc
     9361 aaggttttag aggcctttga tggttatttt gatgtcatca tcaaaacagt ggtacatcac
     9421 cagtttgagg gtgataccta ccgacctagg ttagagctga gtgattttgt agaggagacc
     9481 tctgtattgt acccaaggga cgataacaat ccttacgatt tcactgttac agtattgaga
     9541 catcgctaat atagggagat gatagtctat gcagcgtagt atttttgggg tatttacggc
     9601 ctttttgtgt gcgatttgtg ttttatgtgc cataccggcc tttagaaaaa atcgctatgg
     9661 cttaggatta ctttttttat taaatgcctt tactaaccta gtgaatacca tacatgcctt
     9721 ttatggaaca ctgttttaag cctaagagaa tgaaaagaga aagatagagg aatcatggca
     9781 ggaaatcgta gtaacgatat taaggttcat tgctcgtttt gcggcaagag ccaagacgaa
     9841 gtgaaaaaaa ttattgcagg taataacgtc tttatttgta acgaatgtgt tgccttatca
     9901 caagaaatca tcaaggaaga attggcagaa gaggttctcg ctgatctgac tgaggtacca
     9961 aagccaaaag agctgcttga gattttaaat caatacgtca ttgggcagga gcgtgctaag
    10021 agagccttat cagttgcagt ttacaaccac tacaagagga tttcatttac tgagagtcgt
    10081 gatgatgatg atgtggattt gcagaagtcc aatattctga tgattggacc aacaggctca
    10141 ggaaagacct ttttggcaca gaccctggct aagagtctga atgttccgtt tgctattgct
    10201 gatgcaacct ctttgactga ggcaggctat gtcggagaag atgtggaaaa tatcctcctg
    10261 aaattaattc aagccgctga ttacaatgtt gagcgtgcag agcgcggcat tatttatgtt
    10321 gacgaaattg ataaaatcgc taaaaaaggt gagaatgtct ctatcactcg tgacgtatca
    10381 ggagaaggtg tccaacaagc cttgctaaaa atcattgaag gaacggttgc tagtgttcca
    10441 ccgcaaggtg gtcgtaagca cccaaaccaa gagatggtac agattgatac caaaaatatc
    10501 ttgtttatcg tcggaggcgc ctttgatggt atcgaagaaa ttgtcaagca gcgcttggga
    10561 gaaaagatca ttggctttgg gcaaaatagt cgaaagattg atgacaatgc ttcctatatg
    10621 caggagatca ttgctgagga tattcaaaaa tttggtctga ttcccgaatt tattggacgc
    10681 ttgcctgttg tggcagcgct tgagcagctt aatactgagg atttgattcg tattttaaca
    10741 gagcctagaa atgcccttgt gaagcaatat caagccttat tgtcatatga tggcgtagag
    10801 cttgagtttg aaaagggggc tctggaggct attgcaggta gggctattga gcgcaagact
    10861 ggtgcgcgtg gtctgaggtc tattattgaa gaaaccatgc tggatatcat gtttgaggtg
    10921 ccaagccaag aggaagtaat caaggtacgc attactaagg aagctgtcga aggtcaatca
    10981 aagcctattt tagagatagc ctaaggaggt atgatgtctg aagagcaaat ccttaacacg
    11041 cataatgctt cgatattgct tagtgcggca aataagtctc attacccaca agacgacctt
    11101 cctgagattg ctttggcagg tcggtcaaat gttggaaaat caagctttat caatactata
    11161 ctaggacgta aaagccttgc tagaacctca agcaaacctg gtaaaactca gcttcttaat
    11221 ttttttaacg ttgatgataa gctaaggctt gttgacgttc ctggctatgg ttatgctaag
    11281 gtatctaagg cagagcgggc tagatgggga aagatgatcg aagagtacct gaccacacga
    11341 caaaatctca gagcagttgt tagtctggtt gattttcgcc atgagtcatc acaggacgac
    11401 attcagatgt atgagttttt gaagtattat gagattccgg tgattattgt ggctacaaag
    11461 gcagacaagg ttcctcgtgg tcgctggaat aagcatgagt ctatggttaa aaagtcctta
    11521 aactttgatc aaacagatgc gtttattatt ttttcatctg ttgagcgtat cggtattgat
    11581 gagtcttggg ataccatttt agagtattta taagcatatg gtaaaaaatt taagtatctt
    11641 ttagacaggc acttgtgtct ggtctgagag gtgctttttt attgacaaaa aaacaatttg
    11701 ttgatgacga gcttgtgttc aaaaatgtca gtttgctaaa aaatgatgat aacaaacaag
    11761 acttttatga tataatgctt agcaggataa tatggagaca tgagaaaaag gtcagagaca
    11821 gctaatttgc tatccctgat tataactatg atgaccagca ttattataat actcatggtg
    11881 ctagctatta gtagcagcac ctaacctata gtgttgcttt ttaggttaca agcactggcg
    11941 ctaggagtat tataatatat ttagaaaggt ttttttatga caataaaaaa atgccctcaa
    12001 atacttgcct tattccttgc ttttgcagcg ctagctagtc aggggcaaac cgtccatgct
    12061 ctggagcggc aggagacatc tgtcaagcaa gctcatgaat cagatgattg gtttgatgag
    12121 gacgaaggag ttagcgatat caagtctaat acccctacag agatagactc aacagtaaca
    12181 gagttatttg gtgatgctga gcctaagact aaggctgaaa aagaagagtc aaaagctcca
    12241 agccctaagc aagaagcact gccagcagag tctcaaaaag aaaaagagac atctgctaaa
    12301 tcgactgacc atgcgacagt acaagcagaa gaggcacagc ctgagcaagg ctcagatagt
    12361 ccttggctag cagatgactt tgttactaag ggagatacct tggttgggct atctaaggca
    12421 ggtcttgcta agttatcaaa gacacctgtc ttggtactac caaggatagg gattgacaag
    12481 acagtgttga caaggattgc tagctttgcc tttactccaa ataaatcagt cgctattgct
    12541 gattatacag gtagagcagg tgaacatggc gagatcaatc atctggacgt cgaaggcaga
    12601 gatatcctta ctgagggaga ggattttggt gcctatgcga ttaaaaagct tgtgattcct
    12661 gaaggctatc tttttatcgg tcaagatgcc tttaatgaca ataaacagct agaagaaatc
    12721 agtctacctg atagcttact cagtatttca gactatgcct ttgctcacat gagtttatct
    12781 aagcttaagc tgccaaaaag cctacagtcc attggagatc aagccttttt tgataatcgg
    12841 attgcaggca ctttggtatt gccaaaagct ctaaagcagc tgggagaacg cgtctttaag
    12901 tccaatcgcc tcactggact tgtctttgag ggagaaggct tgtctgtcct aaaagaagca
    12961 gcctttcaag acaatgcttt cattagtctt gttatcccag atagcattca agccttagaa
    13021 gaggacgtct ttacaggaaa ccttggcgat gaagaatacg gtaatcatgc cgttttacga
    13081 accaaaaatg gtcagaatcc ttacagactt cacagtgcca atgttcttgt caatccaagt
    13141 gatcaggcta gaacaccaca gccaccaatt gattacaaca ggtggcttgc agaagatttt
    13201 acctatactg gacagacgat aaccggtttt tcagctagtg gactgcgcaa ggtcaaacgc
    13261 aataagcatt tggttctgcc taagaattat cagggtcagc ccttgacagc cattgcagat
    13321 aatgccttta gaaatgtcaa ttttcatgat aaaaccttgc gtaaatacga cctagaaagc
    13381 gtgacgttac catctaccat tcaaaagatt ggtgcctttg cctttcagtc aaataatcta
    13441 gaaagctttg aggccagcga ggacttggtt gagattggtc aaggagcctt tatgaataat
    13501 cgcattgaga ttctggcctt gaatgataag ctgaaggtca ttggagatgc ggcctttcat
    13561 atcaatcgga tttatgctat tgttatccct gagtcggtcg aagtaattgg catttctgcc
    13621 tttaggcaaa atggtgctaa acatgtgatg tttatgggag ataagctaat aagtattgga
    13681 gaaatggctt ttttgagcaa tactctggag gaagtggatt tgagcagctt agcagggctt
    13741 aagaccatcg ctgttcaagc ctttgcagac aatcacttga gagagcttaa gctgccagat
    13801 agtttgatgc gtattgaagc agaagctttt aaaattaata gacttcaaag agtgaccgtt
    13861 ccagacactg tcattagcat tagctttaat gcctttgatc ataatagtga tgacaaggtt
    13921 gtcctaagga ccaccaatca caataaaaac ctgctagctg atggaaatgg ctttattgtg
    13981 gatccagacc tattaagtgc ggatcaatcg actgttcaag cagttttaga ggacctgcgg
    14041 cgcttagatc tagctagtct acgtgctgat acagcagctc attttatgac actcatcaca
    14101 agaggtaagc agctactaaa agaatccgct gtacggttag gttatcagct taggttcctt
    14161 gcagagtcac gatttttctt agggcgcgtg agactggatc agctgattaa aactgctgac
    14221 ataaccctat ctagccatca agacacacct aatgctaagc tgttgatggc taagctagac
    14281 aaggccaagc tgcattacaa taatagcgca atgactgctc caaaagtaag tcgcttggaa
    14341 aaagagctca gcctgttaat tgatcttgtc caaggggtag gcgctatctc taaagcaaca
    14401 atgactcaag gtgtctataa gcttcagaca accctaccta ttccagagta ttatattggg
    14461 gttaatcttt atactgatga tcaggggaat attttatttg tgcttgacat gagtgatacg
    14521 attgggcagg gacaacttga tgactatggc aatcctattt taaatgttga tgaggataat
    14581 gaaggctacc atgctttggc cattgagtcc ttagcagatt acgaaggcct tacgattaag
    14641 gatatattga ccaaggagct aaatcaattg cctattcgcg atgtcaagca agcaagagag
    14701 catcgtgttg gtctttttat ggcaatcaga gatgctgcaa gggaagctca gcttctacta
    14761 gaaaagcaga gcaaagcctt atcagaatca gccggcaaat ctaatggctc aaaagtagct
    14821 gactcaggac ttgagccttc tgtgacacta tcaaccaata agactaagct gctaccaaaa
    14881 acaggagcct tcaaagaagc ttgggtgaca atgatcggaa tgcttgttct tttggcggct
    14941 accctactta aaggcgatag tcgctacaaa aagaagtaaa taggcttgct tagcaagcac
    15001 actctagcac cagtaaggct tgaggggctt acaaagccta tctaatctag caatagtata
    15061 ttgccagtgt gagctggtgc ttgagcttca aaaaaacaaa agagcctgaa atgactttta
    15121 ctagcatttc aggctctttt tagcttgtga ttcttttttg tgtgaagctt acttctcact
    15181 tatcgtaata gtatcttgat caaggcttgc taataggtgt ttagcagtcg ggtgatccag
    15241 gtagtaatcc gtaatgcggt cacgaatttc ttgttcgatg acacgtctaa gtggacgaac
    15301 tcccatcgca tgatcatagc ccagatcaat caaacgctct ttaacatcgt cagtcacctc
    15361 aaggctaatg ccttttttag caagggtttg gttcacttct gttagcatta aagcaacaat
    15421 ttcttgtaaa tcctttttcg ctaaatggtt gaattcgatg acaccgttga agcgattcaa
    15481 gaattctggt ctaaagtaag gtgcaatacg ctccatgata gcaggctctt gatcagcacg
    15541 atctcctgct tgatggccaa aaccagcatt agaggttgcg atgataaccg tatttttgaa
    15601 attgatcgtg ttgccttgtc catctgtcaa tcgcccatca tcaagcactt gaagaagcag
    15661 tgtaatgacc tgtgggtctg ctttttcgat ttcatcaagc aagatgatag agtaaggact
    15721 gcgacggaca cgttctgtaa gggtattttg attatcatca tagccaacat agccagctgt
    15781 tgttccgatt aatttggaaa cagctgtgcg gtcactatat tcagacatat ctaagcgaat
    15841 gatagcgtcc tttgagccga acatatcaag ggctaactgc ttagccagct cggtcttacc
    15901 aacaccagtt ggaccaacaa agaggaagga gccaattggg cgattaccgt catcaaagcc
    15961 tgcgcggttg cgtcgaatcg cacgagcaac agcctcaact gcaccatctt gtccgataac
    16021 atggccttta agacggttac tgatttcctt gagcctttct aaatcactag cccccatatt
    16081 tgatactgga acaccagtta gacgttcaac agattctgca atatcattaa cagtggcagt
    16141 gaccttttgc ccttcactgt gatgattgat ttgcttttgg agctcctcaa tgcgggtctt
    16201 agcagttaag gccttttcaa agtcttcttc tgcaacagcc ttttcctgta gctccttttg
    16261 cttagtgatt tctgcttcaa gtgattttag atcagtgaca gggtgctgag ctgctagatg
    16321 agcagcagtc atatcaacaa ggtcaatggc tttatctggt aggcttcgtt gtggaatata
    16381 ttggatagca taatcaatag ctgccttcaa gacagagtct ggtaggatca cattgtggtg
    16441 ctgctcgtag aggttgcgaa tgcccattaa aatgtggaag gtatcctctg ctgaaggagc
    16501 attaacctta acctcgttga aacgacgagc aagagcagca ttttttagaa tggtgttgcg
    16561 atactcatct tgagttgtgg caccaatcag ggtcaactca ccgcgtgaga gggctggttt
    16621 tagaatatca gctaagccct tagagcctga gtctgaacca gctgaccctg caccaaggat
    16681 ttgatggatt tcgtcaaaga agagaatgat attgccagcc tccttaacct ctttaaccat
    16741 gttttgaatg ttttcttcaa aggagccacg atactgtgtg ccagcctcaa ggccagaaat
    16801 atcaattgag ataatctctt tatttttgat ggcagctggc acatcaccgt tgacaatagc
    16861 ctgggctagg ccttcgacaa cagcagtttt accaacacca gcgtcaccga caagaacagg
    16921 gttattcttg gttcgtcttg ctagaatttc tgcggtcgct tgaatctcat cgtttcgtcc
    16981 gatcacagga tctaacctgc cttgccgagc ttcttcggtc aggtttgttc cgagcttggt
    17041 tagaatgccg tcttttttaa ggctgctagc ctgtttttct tgtccctcag ctgcagctag
    17101 cttaccggtt ttccggtatt cttgaaattc ctctggtgtc atctcacgtc cattgacaag
    17161 atagcgacga ttttcgctgc ggtagccgcc gatgtttccc attaactgat tgaaaatatc
    17221 gtccatattt tcaaaggggt cttttccata ataggttgcc atatacactt acctcacttg
    17281 tattatattt accagtcatt atgagctact ggtataggta gaaggtgatc ggtgttggct
    17341 catacagaga tcatagagag gtcttatgag agtctattgc tcaggcttat tactcacctt
    17401 ctaataatat tatatccaaa aggtcagtaa aggtcaaaca aaaagtatga ataattaacc
    17461 tttataatca ggtgcttata gcccttgaaa catcagatga ctatgccata agctgctggt
    17521 gcttttttgc tagcaaggct atctgtaaag aagagacttt tgtcaaaaat ggttttactt
    17581 tttgttctaa aggctttcat gatataataa aagaaaagca cagaggtcaa ttatggaaca
    17641 aacatttttt atggtgaagc ctgatggtgt gaaacgtggc ttggttggag agattctacg
    17701 ccggattgag cgtcgtggct ttacctttga taggcttgaa ttgcgacaag caaccccaga
    17761 attgctagct aagcattatg acaccttaat caataagccc ttttatccag agctagaggc
    17821 ctatatgaca agcggacctg ttttaatcgg cattatctcc ggtaatcgtg tggtctcttc
    17881 ctggcgaacc atgatggggg taaccaatcc taaagacgct ttaccgggga ctattcgtgg
    17941 tgattttgct caagcccctg gtgatgatgg cggcattttc aacgtggtgc atggttcgga
    18001 ttcgagagat tcagccaagc gagaaattgc gatctggttt ggacatagct gacattgggc
    18061 ttgggcctat tcttttaaga actgataaag caattgcata aggagttgat aagcccatca
    18121 tcaatagtag ctcagcatta gaagggtaac agccttgatg ttgggctatt tttttgcttg
    18181 cctagggtct gtatgcttgt cctgatgagc aggtagacaa agcagcataa gtttaacaat
    18241 cctttgcggc agtgatcaat tgtagctcta accatagcat cagctatttg aaagccttga
    18301 aaaagaaagc taaggctaac aagctagtct aggtcattta ctacaagcga cttttttcaa
    18361 ttagctgctc aaggcaagta ttgaaaaaag tccatttttc atgtcatttg taataatatg
    18421 gtatattttt aacgaaaagt cgttttagtt gagaaaatat acaaaaaagg ctatgatata
    18481 gttaataaag ttgttatacc ccctgtgtct tgtacactat gacttgtaga gagtttatca
    18541 aaggaggata agatgaacaa acaaagcatg acccattttt ctaagaagct gatgaagtta
    18601 gcccttttag gtttggcatt gccattaagc ttggtgtcgg tggtagatac tccggttctt
    18661 aaccaatccg aaaaagctgt ttatgccaat gattttggat ctggaaatcg agccagtgat
    18721 tatgtaccgg cggctaacgc ttggagcttt gaggcttatc cagattacta cagtatttta
    18781 ggagctagtc atcttaatcc tgctgtcttt ccagagccta gtaagatgtc atacagtcct
    18841 ttagacgagt tgggccgcac acaggtcgca agaggaacaa taacctatca caatatcgtg
    18901 atgaattaca atgttcggca acgctttgct aaaaatcaga acccttcagg ctggattggt
    18961 aaccctagaa atgttcgcta cactattgag tggctagatg gactatccta tcagggagat
    19021 ttttggaatc ggagtcattt gattgcagat agccttggtg gagcagcctt acgtgtcaat
    19081 gctattactg gtacaagaac acaaaatgtt ggcggcagaa atcaaagagg cggtatgcgc
    19141 tatattgagc aaaaggtgca gcagtggatt gagcagcata caagcgcagt tgtttattac
    19201 gaagcggtgc caatttacca ggcaaatgag ctagttccaa gagctgttgt tgtttcagca
    19261 ttgtcatcag acggaggtct tgacgaaaag gtcatggtct ataataccgc caacggctat
    19321 accattgatt atgccactgg cgcattccgc agtaactagg cttttgtact aagctgtagc
    19381 tgatcaaggt ctgactaaga caagctcatc agcaattggt atataaaaag acgtggcaac
    19441 aacatgtttt aaatgagttg tcatgtcttt ttagtgtcgt cagcttttca cattgtctta
    19501 gaatgatcac acctagctag ccgctaaaag cattggtcca aagaaatgtt aagaatagat
    19561 agaatgcctt ttaatcagtg gtatgggact gctagctaat ataatgcctg cagttgagcc
    19621 aatttctcat ctaggctaat aactaacaag ctattgactt atcgtgttca ttagaatgtc
    19681 agctgttgta gttggtagta ttcgaatacg attaagcgat agcaggccat tagcagcact
    19741 tgctagtcct tcatttgttg tgacccctaa tttgtaatgc agatcctcag caatctttaa
    19801 tgtggtatca gtataacgac ctgctggata ggcaattgca atggtatctt ggtgtagctc
    19861 tctatctagg tattctttag aatctttcat ttcagcggtt tgactagcag cgcttgcctg
    19921 agatagatca gggtggttaa ccgtatgatc ttggaaagac atgcctgcct gcttcatttc
    19981 cttcatctga tccaatgtaa gattggccgc attacctgcc tctgtaaagc cagtgataac
    20041 gttattggtg gccttgatgt catacttttt caggattgga aaagcaacgt tgtaaaaatc
    20101 aaccatgcta tcatcaaagg ttagccagac aaccttttca gcaggaagct cgttagctga
    20161 taagactcgg taggcttctt cgggagataa aaagtagtag ccggcctcct tcattgcctt
    20221 tagctggctt tcaaaaagat ctggagcaac gatgagattg gcacttgctg cctcttctgg
    20281 tgccataacg tgaatagcat gatacattaa gataggaagc ttaacagggt tttgctgctt
    20341 ggtccagctg acagctcctt tttgctgctg actatttgta tggctagctt ccttattagt
    20401 tgcttttttg ctaggcttgg gagctggttt tttatcagtt tttgaaaata ggcttatttt
    20461 ggggattgcc tgcgataatt gagagatgct tatctttgaa tggctcttgt aaaggtagac
    20521 aatagctgat aagcctatga tacaggcaag tagtagcatg agattaatca ttttgaagat
    20581 ttttcttttc ttacgccgtt tgtttctgtt gttcatcact tgctccttgt ttattgatta
    20641 gtctattgta acattttttt aagtaagctg tctttcgtta acttaatttt ttgctaacat
    20701 tctattagtg ttatgctttg taaaacaaga cctagatttg ctataataag acagagtatt
    20761 taagacagtc aaaaaaagga ggataggatg tcagttaagg ttgcattatt aggctttggg
    20821 actgttgcta gtggcattcc cttgctatta gaaaacaata gtagcaagat tcgtgcagtg
    20881 gtaggtgatg atttggtgat tgcaaaggtt ctggttagag atgagaccac taagaagcgt
    20941 ttgttggatc aaggctattc ctaccaattt gtgacctcca ttgatgatat tgttgatgat
    21001 gagagcattg atatggtggt cgaattaatg ggtcgtatcg agcctgcaaa gacctttatc
    21061 tcgcgtgctc tatcagccgg aaagcctgtt gtgactgcta ataaggattt gatagccttg
    21121 tacggaggag agctctcgac tttggcagct aagcatcagg tagctttgta ctacgaggct
    21181 gctgttgctg gtggtattcc aatactaaga gctttggctg attcctttgc ctcagataag
    21241 ctgacgcgtc tgctcggtgt gctcaatgga acaactaatt tcatgttaac caagatgatt
    21301 gatgagggct ggacctatga aagggccctg caaaaagcgc aggagctggg ctatgctgaa
    21361 agtgatccga ctaatgatgt gaaagggatc gatgcagctt acaaggttgc tattcttagt
    21421 cagtttgctt ttggaatgac cattgacttt gaggctatta gctattcagg gattgataag
    21481 gttcgagtag aagatgtgac agtagcgcag aagctgggct atgtgatcaa attagttggt
    21541 ctacttgaag agacggcttc tgggcttaac gcagaggtat ccccagtctt tttaccaaag
    21601 acacacccgt tggctgctgt agacggtgtg atgaatgctg tttatatcga gtcaattggg
    21661 gttgggcagg ctatgtttta tggtccaggt gccggtcaaa tgccaacagc tacagctgtt
    21721 gtggcagata tgattcagac tgcctgcacc ttacgtgacc atacagtctc agtctttaat
    21781 cgttttgcta caaaaactag actagctaag tctgaggata ttatgagtcc ctattacttt
    21841 gctattcaag caactaataa gtttggtcag ctactagagc taacaaggct atgtgatgtt
    21901 tgtggcatta gagttgagca gctgttatca gatgagatag atagtgacag gttagacttt
    21961 gtgatgatta ctcatgagat gagcaaaaag gagcttgctt gctttacagc gctactacag
    22021 gatcatcagg atttccgtat gttaagtaca tttaagattt taggagattg acatgaagat
    22081 acgcgtacct gcaacctcgg ctaatttggg acctggattt gactcaatgg ggattgctgt
    22141 ttcaaaatac ctagaagttg acattttaga agaacgtgac caatggttta ttgagcatga
    22201 tttgggtgat attccaaatg atgatagcaa cttacttatc caaacagccc ttaggctagc
    22261 accaaatatt ccagcacatc gtctaaagat gacgtctgat attccattgg cacgtggctt
    22321 gggatcgtcc tcctcggtga ttgtcgctgg tattgaatta gctaatcagc tagggcattt
    22381 aaacctaaca gacgaccgta aattggccat agcaactcgt attgaggggc accctgataa
    22441 tgtagctcca gcgatttttg gtcaattggt aattgcttca cagattggta aggacgtgga
    22501 ttacatcatt gcgccttttc ctgacctttc tttggtttgt tttattcctg attatgagct
    22561 gaaaacctct gattccagag atgtattgcc caagcagcta tcgtataagc aggcagtggc
    22621 tgcttcctca gttgctaatc ttgctatagc tgcgctattg accggtaatt tgaaaaaggc
    22681 cggtcgggcg attgaaaatg accaattcca cgaaatctac cggcaaagat tagtcagaga
    22741 gttccagccg attaagcgag ctgcagcagc taatggtgct tatgcaacct acttatccgg
    22801 tgcagggcct gctattatgg ttatgtgtcc caataagaaa aaaatggcga tttatgaggc
    22861 catcgagcag ctaggtctaa ttggtcagtt ggtgtctcta gagctggatc gtcaggggct
    22921 gtgtcttgtc tagactggca aggtactggt atgcttgcct agtaggctta ttgttgatat
    22981 cagatggact taaagcttag tcattcaaat acatcaaaaa agtgaggctt gatcgtttta
    23041 tcggctttca cttttttctt gatatgttat actagagtag actttgtgag gtgtgtgatg
    23101 aattatcaag aaacattaga ctggattcat ggtcaggaaa gatttgggat caagccaggt
    23161 gtaaaacgca tgcgttgggt gcttgagcag ctaggtaatc ctcaagatag gattagagga
    23221 atccatgtgg tcggcacaaa tggtaaggga tcgacggtca atgacctaca gcatattttt
    23281 actagagcag gctatgaggt tggaaccttt acctcgcctt atatcatgga ttttaaggaa
    23341 cgtatctgtc tcaatggtga gatgatctca gagactgacc ttgttaaggc tgctaattgt
    23401 attcgtccac taacggatcg ccttatcagt gagacaagtt tgggtcctgc aacagtcttt
    23461 gagctgatca ctctgatcat gtttctttat tttggtgaga gtcacccggt tgatattgct
    23521 attatcgagg caggattagg ggggctttat gactccacta atgtgtttca ggcgatggct
    23581 gtggtttgcc cgtctattgg tcttgatcat caagctattt taggtgatac ctatgctgac
    23641 attgcctatc aaaaagccgg tgtgctaaag ggtggtgaag accttatttt tgccattgat
    23701 aacaaagagg ccagacaggt ttttctaaaa aaagcagagc agcttggcgt gcctatttgg
    23761 gaatggcgtc gacagttcaa catgctacag ggtgaaggtg gttatcaatt taacagtcag
    23821 cttggtcagc tgtctcatct agtgcttgca atgcctggtc agcatcaggt agccaatgca
    23881 ggcctagcca ctatgacaag cttgatatta caggatcggt acccaaaggt aactgagtct
    23941 gttattagag aggctctggc aagcagcttt tggttgggac gaacagaatt gttggcaccc
    24001 aacctgatga ttgatggtgc tcataataat gaaagcattg ccgccctgat tgatgtgata
    24061 tcatcagact atcaggataa gcagattcat attctatttg gtgccattga taccaagcct
    24121 gtctcagata tgctgcagag tctggagcgt cttggagatg tgcaagtaac aagctttcac
    24181 tatcccaatg cctatccttt ggaggcttat ccagataggc taacaaaagt agcagatttt
    24241 agagcatttt tagaccggct tgagcaagca gctgctgatg attttttcct gattacaggc
    24301 tctctttact tcatctcaga ggtcaggcag tattggaaaa aggtattaag caagtaatgc
    24361 tttctcacat caactcatca aacaagatta atcaactaaa aaggggaaaa ccattgccaa
    24421 tcaatcaaaa aaaagcagaa gccgctatct atcaattatt agaagctatc ggtgaggatc
    24481 caaaccgaga agggctacga gataccccaa agcgtgttgc caagatgtat ctagaaatgc
    24541 tctcagggct ggaacaggac gctaaggatg aatttacagc tgtttttaca gagcatcacg
    24601 acgatttggt gattgttaag gatattagct tttattccat gtgtgagcac catctggtgc
    24661 cattttatgg taaggcgcat attgcttatt tgcctagtga tgggcgtgtg acaggcttga
    24721 gtaagctggc aagggcagtt gaggtgacga gcaaaagacc tcagctgcag gagcgtttga
    24781 cagctcagat tgctaatgct cttgttgatg ccttgcagcc caaaggggtt tttgttatgg
    24841 tagaagcaga gcatatgtgc atgaccatgc gaggtgtcaa aaagccaggc agtaagacca
    24901 ttacgacaac tgctagaggg atttacaagg atagtagaga cgacaggcgt gaggttatgc
    24961 aattaatcat ggagggctag ggtatttatg actattggac attattcagc cgctggtgag
    25021 gcagctatta tggggatttt aaatgtgact ccggattcgt tttcagatgg tggctcctat
    25081 actagtgtta atcaggcctt ggcacaggcc gaaaaaatgc tgtcagaagg agcgactgtc
    25141 attgatattg gaggcgagtc aacacgaccg ggctgccaat ttgtgccggc agaagaagag
    25201 attgcacgcg ttgttccaat cataaaggcc attaaaaaac ggtatgatgt ccttattagc
    25261 attgatacct acaagacaga aactgctaga gcggcccttg aagcaggagc agatatgctc
    25321 aatgatgtct gggcaggact atatgacggt caaatgctaa gtctagccgc cgaatacgac
    25381 gttcccatta tattaatgca taatcaaacc aaagaggctt atgctgatgt tacaaaagag
    25441 gtttgcagct ttttacaggc tagagcagct gcagccctca aagcaggtgt caaaaaagaa
    25501 catatctggc ttgatccagg atttggcttt gctaaaaatg ttgagcaaaa tatagcctta
    25561 ttaaaagggc taaatgaggt ttgccagttg ggctatcctg ttctttttgg gatttccaga
    25621 aagcgtgttg tagacgccct acttggtggc ggcactaaag ccaaggatcg tgacggggct
    25681 actgccgccc tatcagccta cgctattaat aaggggtgtc aaatggtgcg cgtgcataat
    25741 gtcggtgcta acagggatat tgtctctgta ttgagtcaat taaggtgaga aatgatggat
    25801 aaaatcagat tagaggcttg tcgcttttat ggttatcatg gtgcctttaa ggaggagcag
    25861 gtcttaggtc aaatttttgt agtggattta gaattatcag ttgacttgat ggctgcctct
    25921 ctttcagact gcctagagga tactgttcat tatggtttag tttttgaaac agtccgtcaa
    25981 attgttgagg aaaagacctt tacgcttatc gaacgtttgg ctggtgccat ttgtcaagag
    26041 ctatttgccc agtttttgcc tattaaagcg attaaaatcg ctattaaaaa agaaaatcca
    26101 ccgattgcag gccattatca agctgtcggt attgaattgg agagaaagag atgacacttg
    26161 tttatttagg cttgggaact aatatgggag atagggcagg ctacctacag gcagcagtta
    26221 atgccctatc taagctgcca gagactgagt tactgagaca atcctctatc tatcaaacag
    26281 cagcctgggg aaaaacagat caaaatgcct ttttgaatat ggcttgccag ctagatacta
    26341 ggctgacatc agaagctctt ttggcagcta cgcaggctat cgagcaggct ctgggacgag
    26401 ttcgtcatga aaaatggggc ccaaggacaa ttgatattga cctcttgctg tttggtgatg
    26461 agccgtatca atcagagacc ttggttattc ctcaccctta catgacacaa agagcctttg
    26521 ttttgattcc tttattagag attgcacccg atgtgacctt acctggtagc cagaaaagcc
    26581 tgaggtctta ccttgatgct ttagagcaat cagatgtagc cttgtggtca catgagtatt
    26641 caaataagtt ttcttaaact gtcgttattt ttactaaaat ttgatataat agtgctactc
    26701 tttgctgatt ttttgtctta tattaagaaa tgattgaaga aagaagaaga ttatgatagc
    26761 tgaacttgaa ggcattgata ttcgagagaa tgaagcctta aaacattaca cctataccca
    26821 agtaggcggt ccagcagatt tcttggcttt tcctagaaat cattacgaac tatcccgtat
    26881 tgttgattat gccaatcata atcatattcc ttggatggtc cttggaaatg ccagtaatct
    26941 cattgttcga gacggtggta ttcgtggctt tgttatcatg tttgataagc tcaacgccgt
    27001 ccgccttaat ggttatacct tggaggcaga ggcaggcgct aacctcattg aaacaacaaa
    27061 agttgccaaa tttcatagct taacaggctt tgaatttgct tgtggcattc ctggaagcat
    27121 agggggtgct gtttttatga atgcaggtgc ttatggtgga gagattgctc atattttttt
    27181 gtcggccaag gtcttgacac cagaagggaa aataaaaaag atctcagcca gagagatggc
    27241 ctttggctat cgtcactctg tcattcaaga aactggtgat attgtgattt cagccaagtt
    27301 tgctttaaaa ccgggtaatc atgacagtat ttgtcaggag atgaatcgcc tcaaccacct
    27361 tcgaaagctc aagcagccct tagaatttcc ctcttgtggg tccgttttta agcgtcctcc
    27421 tgggcatttt gcagggcaat tgattatgga cgctaaccta aaagggcatc gtgttggcgg
    27481 tgttgaggtc tctaaaaagc atgcaggctt tatgattaat gttgctgatg gctctgccaa
    27541 ggattatgag gacttaattg ctcatgtcat taggacagtt gagcaggcat ctggcgttag
    27601 gcttgagccg gaggttcgta ttattggtga aagcctttaa tgattgtgtt atcaaaaaag
    27661 aaaaattgtg gaggatttat gacaattgac taagccaatt atcacatttg acaatgtctc
    27721 aaagacattt gaggacagcg ggacacaggt cctaaagaac attaattttg agcttgagga
    27781 gggaaaattt tacaccctgc ttggtgcctc aggatctggg aaatcaacca ttttaaatat
    27841 tatggctggg ctgcttgatg cgaccagtgg tgatatttat ttagatggtg agcgtatcaa
    27901 tgatttgccg accaataagc gtgatattca cactgttttt cagaattatg ctttgtttcc
    27961 tcatatgacg gtttttgaga acgttgcctt tgctttaaag ctgaaaaagg ttgacaaaca
    28021 ggagatagca agacgtgtca aggaaacctt aaaaatggtt cagctggagg gctacgaaaa
    28081 gcgatccatt caaaagcttt ccggtggtca gcgtcagcgt gtagcgattg ctcgtgcgat
    28141 tatcaatcag cctcgtcttg tcctattaga tgagccactt tctgcccttg atttgaaatt
    28201 gagaacagaa atgcagtatg agctgcgtga gctgcagcag cgactgggca ttacctttgt
    28261 ttttgttacc catgatcagg aagaagcact agcgatgagt gattggattt ttgtcatgaa
    28321 tgatggtgaa attgtgcaat caggcacacc tgtagatatt tacgatgagc cgattaatca
    28381 ttttgtagct agctttattg gtgaatcaaa catcatcaat ggtacgatga ttaaagacta
    28441 tctggtttcc tttaacggga aagaatttga gtcagttgat ggtggtatgc gacccaatga
    28501 gccagttgag gtggttattc gaccggagga tttacaaatc accctgccag aggaaggaaa
    28561 gcttcaggta aaggtagata cacagctctt tcgtggtgtt cactatgaaa tcattgccta
    28621 tgatgattta ggcaacgaat ggatgattca ctcaacccgc aaggccattg aaggagaagt
    28681 gattggttta gatttcacac cagaggatat tcatattatg cgcctcaatg aaacagaaga
    28741 agaatttgat gctcgtatcg aagaatacgt tgaaatcgat gagcatgcgg atggcttaat
    28801 caatgctatt gaggaggagc gcaatgaaga aaacctctag cctctttgca gttccctatt
    28861 ttttatggat tgtcctcttt gttatggcac cggttgccct tttgctttat caatcctttt
    28921 ttgacatcga aggacgattg acactagcca attacgagac tttttttagc tcatggactt
    28981 acctgagaat gggcttaaac tctatcttat atgctggtat cgttaccttg gtgacctttt
    29041 tgatttcata tcccacagct ttattgttaa cgcgtttaaa gcacaagcag ctgtggttaa
    29101 tgcttattat tttaccaacc tgggtcaatc tgctcctcaa ggcttatgct tttatgggga
    29161 tttttgggca gcagggtggt atcaatagct ttttaacctt tatgggctta ggaccacagc
    29221 aaattctgtt tactgatttt tcgtttattt ttgtggcctc ttatattgag ctgcccttta
    29281 tgattttgcc tatttttaat gctttagatg atattgatga taatattatc aatgccagta
    29341 aggacctggg tgccaatgac taccagacct tttcaagggt tatctttcct ttgtcgctaa
    29401 acggtgttag agcaggggtt cagtctgttt ttattcccag cttgagtctc tttatgctta
    29461 cgcgtctcat cggtggaaat cgtgtgatta cgctggggac agctattgaa cagcatttcc
    29521 taacaacaga aaactggggc atgggctcaa ccataggtgt tgtcctaatt atcgcgatga
    29581 ttgtgattat gtggctaaca aaggagaaaa gtaaatgaaa aaatttgcca atctttactt
    29641 agcgtgtgtt tttattttgc tctatattcc aatcttttac ttgattgttt attcttttaa
    29701 caagggtgga gacatgaatg gcttttctgg cttgacgcta gagcattata agaccatgtt
    29761 tgatgatagt cgcttgatgg cgattttatt gcagaccttt gtgttagcct ttacaagtgc
    29821 cttgcttgca accattatcg ggacctttgg ggcgattttt attcatcaga gtaaaaagaa
    29881 gtaccaaaat gcgatactgt ctgcaaataa tgtgttgatg gtttcccctg atgtgatgat
    29941 aggtgcctct ttcttgattc tctttacgtc cttgaaattt caattaggaa tcctctcggt
    30001 tttgatgagt catattgctt tttccattcc gattgtggtc ttaatggtgc ttcctcggtt
    30061 gaaggaaatg aatcaagata tgattaatgc agcttatgat ctaggagcaa atcactttca
    30121 aatgctaaag gaggttatgc ttccttatct gacaccgggc attatcgcag gctactttat
    30181 ggcctttact tattccttag atgattttgc ggtgaccttt tttctaacag gaaatggctt
    30241 tacaaccctg tctgttgaga tctattcgcg tgctcgaagg ggtatttcat tagatatcaa
    30301 tgccttatca acgattgtct ttttgttctc aattctatta gtcattggct attattacat
    30361 ttcacaggac aaggaggaaa agcatgcgta agctatactc ttttttagcg ggaattatcg
    30421 gggttatctt gctgcttgcg accctgtcct ttattttgca gaaaaaaacg agctctgcta
    30481 gtcaatctga taagctggtg atttataact ggggtgatta cattgatccc gctttgctga
    30541 aaaaattcac taaggaaacc ggtatcgagg ttcagtatga gacctttgat tccaatgaag
    30601 ccatgtacac caagatcaaa cagggtggaa cgacctatga cattgctgtt ccgagtgatt
    30661 acacgattga caagatgatt aaggaaaagc ttcttgttaa gctagataag tccaagcttg
    30721 ttggtctaga taacattggt caggagtttt taggaaaaag ctttgatccg cacaatgatt
    30781 attccattcc ttatttttgg ggaacggtag gcattgtcta taatgaccag ctggtggata
    30841 aggctcctat gcattgggag gatttatggc ggccagaata ccaaaatagt atcatgctag
    30901 ttgatggtgc tcgtgagatt ttaggtgttg gattgaccac atttggctat agcgttaact
    30961 caaagcacct aaagcagctt gaagcagctg aaaaaaaact acaggcctta acccctaatg
    31021 taaaagcaat cgtcgctgac gagatgaagg ggtatatgat tcagggtgac gctgctattg
    31081 gtgttacctt ctcaggagag gctagcgaaa tgctggacaa taacgaccat ctacactatg
    31141 ttgtaccatc agagggctca aacctttggt ttgataatct ggtgcttccc aaaacaatga
    31201 agcatgaaaa tgaagcctat gcctttatca actttatcat gaagccggaa aatgcagcac
    31261 aaaatgctga atatatcggc tatgccactc ccaatacaaa agcgaaggct ttattgccag
    31321 atgatattaa aaatgaccca gccttttacc caactgacga gaccgtaaag aaattagagg
    31381 tttatgataa tttaggctct aaatggcttg gtatttacaa cgacctttac ctacaattta
    31441 agatgtatcg aaaataggtc atgcaagatt gaaggagcta ttcattggaa agcttcttca
    31501 gtctttttta gcttggtctg gtctcaataa tctcatgaga ttaaaaagaa ctagaatctt
    31561 gctttcgtct ttgatacaat agtagtggtt tattaaaatg aaagagatga caaaatggaa
    31621 aatcataaaa acgagtttac cttttccaaa cattcaatca tagcctacgt ttggcgtggc
    31681 attttagtcg ggataattgc tggagctatt gtcagtttgt ttcgcttatt gattgagatg
    31741 gttagtgagg ctgttgttgg ctattatcac caagctcaca gcaatcgcat gctccttgtt
    31801 ccgatagcag gctttagctt attagctgtt tttttagttg gtcttttggt caagtctgac
    31861 gccaacatta aaggctctgg tattccacac gtcgaagggg agctaaaggg cttgatgtca
    31921 cccaattggt ggagtgtgct ttggaaaaaa taccttggtg gaacaattgc catttctatg
    31981 ggcttaatgc ttggaagaga aggcccttct atacaattag gggctatgtc agctaaaggc
    32041 ttagctaagt acctgaaatc tagtcgtcta gaaaaacgtg tcttgatcgc tagtggagca
    32101 gctgctggct tatcagctgc ttttaatgcg cctattgcag gactgctttt tgttgttgag
    32161 gagatttacc accatttttc aagattagtg tggatcactg ccttggttgc aagccttgtt
    32221 gcgaacttta tttcgttgaa tatttttggc cttagacctg ttttggccat gcctaaggcc
    32281 atgccctttc ttgccttaca tcaatattgg ctgctcttaa tcttaggcct tgtgcttggc
    32341 tgtctgggct ttctttatga agaggtcatt ttacattttc atagggttta tgattttctt
    32401 ggaaagagct tgcgcctagc gccgcatttt catgggctga ttgttgttgc tattatcctg
    32461 ctgattggct attatttgcc acagctattg ggcggaggtc atggtttgat tatgtccttg
    32521 tcagagcaaa agctaccact gttgactgtt cttgcttact tctttattcg atttttaggg
    32581 agtatgttta gctatggcag tggcctgcct ggaggaattt ttttgcctat tctaacctta
    32641 ggtgccttgt ccggaactat ttttggattg attcttcagc aaataggact gttagatcgc
    32701 cagatgattc ctctcttttt agtattggga atggcaggct actttgctgc tgtatcaaag
    32761 gcacccttga caggaatgat cttagtgact gaaatggtag gggatctgaa gcccttaatg
    32821 gccattgctg ttgtgacctt cgtggcctac ttggtgatgg atttgttaaa tggtcagcct
    32881 atctatgaag caatgctaga gaaaatggct atcaaacacc caacagatct agtggagccg
    32941 accctgatcg aattacctgt aagtgagaaa attgcaggca gatatgtccg agacctgaag
    33001 ctacctaaaa acgttttaat tacaacgcag ctccaccata agaaatcaca ggtcgtctca
    33061 ggtgatacgc tattgatttc aggtgctacg atctttttgg tggtcaatga agctgataca
    33121 ggctttgttc gagaggtctt gatgtagagc aaggtcggtt aagcagtcag cagtagctgt
    33181 gctaccgatc aaagaagcag atcagtgctt tttctcatct gatgaaaggt attgatttgc
    33241 tttttttgtg ttattaaacc tttgttagca agagccatag ccttagcagt cgtatctgat
    33301 gaatacctgc tgtctttttg ttatacttaa gtatcaatca aaggagcttt atatgctaga
    33361 agttatttca aaagagctgc gccattacca aaagaataag cttgccgcct atcaaaaaaa
    33421 gaaccaaggc atagaagctg gtggaattgt ttttgctggc gattcgttaa tcgaattttt
    33481 cccgttgaaa aaatatttca aacaggtctc aaccatttat aatcgcggaa ttgcagggat
    33541 agacagtcag tggttgctag agcatattga cagtcatgtg aatgatctgg agcccagtca
    33601 tgtgtttatc ctgattggct gtaatgatat tgggcttggc tttgatcaat cgcatatcgt
    33661 atcgaccatt gttgatctta ttagtcgtat tcgcagtcag tctatttata ctaggattag
    33721 ccttctgtcc ttattgccgg tttctgaaaa tcccgcctat caggcgactg tcaagctaag
    33781 gacaaatagg gctattgatg agattaatca agcattagca atgataccag cgattgaatt
    33841 tattgatctt aacgcctgct taaaggacga gactggtggc ttagcagctg cttatacggt
    33901 agatggcatt catcttaatg cccttggcta tgaacactta gctcaagcta ttagtcccta
    33961 tctatgaaag gtaaaggctg gagctgctaa tttgtaaggg atctttaaaa aacaagcact
    34021 gatgaatcat cattgaaacc cttcagagtg ccgataggct gcacaatcaa agaagcatta
    34081 ggtttgtcta tgacgccctt gtgttaagct ggcttttagg tttatactgc gagaaaatca
    34141 gtcattgggc tgggagtctc aaagcttagc tgtggtaatt aaatgcgagc tcctgctagc
    34201 ttgtgctgat caagcagtat agcaaggagg gactgaactt ttagtctcag ataatattag
    34261 actttttatc ctatattaaa cgatttagtg tataataaac aggaaggagt taaaatgaaa
    34321 tttgaaaaaa aacaagtctt ttatgttgtg cttgcctttg tgctttgtta tgctattcaa
    34381 gctaattggg ataatggggc taatattgtc acaaccgttt ataagacaag cctgcccttt
    34441 ctttatggag cagcagtcgc ctatattgtt aatattgtca tgagtgccta tgaaagagct
    34501 tatacttata ccctaaaacc ctttcctttt gccatgaagg ctagaagagg gctctgtatg
    34561 cttttggcat attttacctt tatcagcttg atcgtatgga ttatttctat tgtaatccct
    34621 gatttgattg caagcattag ctcgttaacg caatttgata caagagctat caaggaggtc
    34681 atcagtgatt taggtcacaa taagctgatt gcacgtgcca ttaattacat tggtggagat
    34741 gctaagctga cagaaacaat taccaattat agccagcagc tgctcaagca atttataggt
    34801 gttctaaccg gtattttgac atcggttaca gcagttgcct cagccattat caatgtggtt
    34861 atcagctttg tcttttccct gtatgtgctt gctagcaagg aagagctttg tcagcaggca
    34921 actaccttaa ttgacaccta tactggtaaa tacgcaaagg ccattcatta tttagtgggt
    34981 ttgctgcata gtcgttttcg tggcttcttt gtgagtcaga cgcttgaagc aatgatttta
    35041 ggctccttga ctgccattgg catgtttatc ctgcaattac cctttgcagg aactattgga
    35101 gtcttggttg cttttactgc cttgatccct gttgttggtg cttcaatcgg tgctgcgata
    35161 ggctttgttt tgattatgac tcagtcaatg tcgcaggcag tcgtctttat tgtctttctt
    35221 gttatactac agcaaatcga ggggaatttt atttatccca gagtggttgg tgggtctatc
    35281 gggttaccag ctatgtgggt cttaatggca atcaccattg gtgctgctct caaaggcatt
    35341 gttggtatga tcgttgcagt gccattagcg gcaacgcttt atcaagtggt aaaggatcac
    35401 attcataaaa agcaggcctt acaaaatcgt cagtccagct aattaacagc atcagatcaa
    35461 ggaaaacgtc tattacaaga ccgatttctt ggtcttttat gctgtctgat tgactgcgta
    35521 tggccttatt tttatgctgt ggtaatgaaa aaagccgtct tatttatcga atatcattag
    35581 tggaggtaat aagatgtatt ccatcaaaac tgatcataaa ttaatgccta gagagcgttt
    35641 gattcgactg ggtccagaaa agctaagcaa tcaagagcaa ctagcgatcc tacttaggac
    35701 aggtaacaag gaaaagcatg tcttagagtt gtctgcttat ttattgtcaa gcttagatag
    35761 tctagctgac ttgaagaaat tttctttaca agaactacag cgcttatccg ggataggaaa
    35821 ggtcaaggct attgagatta aggccatgct ggagctggca gaccgtattc agatagcggg
    35881 acaagcagta gcagatcctg tcttatctag tgctcaggtg gctgaaaaga tgatgattga
    35941 attaggagac aagcagcagg agcatttagt cgctatttat ctcgatagtc aaaataaaat
    36001 cattgaagaa aagacgatat ttataggaac cgtcagaaaa tcaattgcag agcctagaga
    36061 aattctttat tatgcgtgta aaaatatggc gactagcctt attgttgttc acaatcatcc
    36121 ctcaggcctg accaagccaa gcgcaaatga ctatcacttc acagaaaaaa taaaacgatc
    36181 atgtgattat ttaggactta tctgcctaga tcacattatc gttagtaagt atgactacta
    36241 tagctttcgg gaaaaatcag atttattttg agttagaaac tatggataaa ccaatcaaag
    36301 agccttaggt cttcttctct aatagcctga agcagctctg ggtgccactg gacaccgaga
    36361 aagggaatat caggattgca ggagataaca gcctcgatgg tgccatcgtt aggatccctt
    36421 gcaatcactc ttaagtcctc tgcgacctgc tttaggctct ggtggtgaaa tgaattaatc
    36481 agcgctcttg gaccatagat agggtacaaa ggtgaagtct tttcgatcac tatctcctgt
    36541 gataaacagt cagaggcagt cttttgccaa tggccctcaa tgtgctggtt tagactgcca
    36601 cctagagcaa catttattaa ctgcataccg cgacaaatcc ctaaaattgg ttttttctgc
    36661 gctagggctt ctttaatgat ggctagctca aagatgtcac gctggggtga aaaatcacca
    36721 tcaagtgcag ctcttttttc atgataatat ttaggatcaa catgctgacc accaataaga
    36781 atgattttat caaccattgc gacataggat ttggcagccg cctcatcccc aatcggaaga
    36841 agtaagggta ggccaccaga tcttgtcaca gcctcgatga agcttgttgg agcataggag
    36901 caaggcaggt tatctagagc cttggtcccc ctttggttag cagttatccc aataattgtt
    36961 ttagacacga ccttctccat taatcaagat gattttggtt cataaagtat agcaaggttt
    37021 gcaactcgct ggtcaaatca acagattgga cgatcacacc ttttggaacc tgtaagtgaa
    37081 gtggagcaaa gcttaaaata ccgcgaatgc cagcttcaat cagttgatct gcaacctctt
    37141 gagcatagat gcttgggact gttagaatag ccgtttcaat gcctgaatta tccaggtgct
    37201 ccttaatggt agaaatgcca taaataggaa tatcatcagg cgttttggtg ccgaccatag
    37261 gattatcatc agtgtcaaat cccataacaa tctgcatttt gtttcgatcg tggaagcggt
    37321 agtgaagaag tgcacgacca atattgccgc agccaactaa aatcacatgc gttgttgagt
    37381 gatcatttag caaatctgca aaaaaattca ttaattttgt gacatcatag ccaaatccac
    37441 gtcggcctaa ttcaccaaag taagaaaaat cacgtcgaac agttgcagaa tcaattccca
    37501 tagcatcagc aatctgtttt gagcttgcct tttcaacctg atcagcataa aagcgtttaa
    37561 aaatacgata atagagtgat aagcgttttg cagtcgcttt tggaatagat ttatcaataa
    37621 ccacttttgt agctccttct attgttattt taatgttatc tatcaccatt gtagcagata
    37681 gattgtgaaa tatgcaacta tttgaccatt ctttttgtgt ttttcgttat aaaatgactt
    37741 gacagcacaa gcattggtat ttttcaaacc cagtcacctc gagtataaaa aagcagacaa
    37801 tgaagcactt gccctttagg tcagctgcga tggctgggct tgtcttgtta aaggcaaatg
    37861 tactgtcatt gtctgatatt tctctgagat tagaagagct cttgtgtgct tagcattctt
    37921 ttttaatgaa aatatcacgc tcaacaaggc tatccattaa aaagtaaaac ttgtcctgta
    37981 gtatgctatg ctcttcagat ttaaaaatgt tcaccagtct tagaccggat tggtctgtta
    38041 tagctagctt aaagccatct aaatctttat taatcgtaat ttttaaaggg aagccctcac
    38101 ccgaattagg gactttttcc agtagtcgtg ttaactgata gtgaccaatc ttggtctgac
    38161 taaaggttgt gtctcttagg gtgtattttt taatctttgg gctaatcctg tagctgtatt
    38221 tgcagtcttt aagggcaatt tctttttcaa atgccatatg atcctcctaa aatatttttg
    38281 agctgggttg ctagtgcgat aacgtctttt tgagtatttt gctctgaaaa gctaactcga
    38341 atagcttctg tgagacgatg ggactgcttg ccgaaataag ctgccaaaac gtgacttggc
    38401 tcaacagcac cagctgtaca agcagagcct gacgacacag caaagcctgc taaatcaagc
    38461 tgagtcagta atacatgatt ttggtaacca ggaaagccga tattaatgat atagggaaga
    38521 tgacactcat tatgattgag ctgataagaa ataccttcta attcactaag caagagctgt
    38581 gatagctctt tagcatgctg gtaatgctgt ggcagccttg agacagcctc atctaatgct
    38641 tgggtcatgc cgacgatatt aatcaggctt tcagtgccgg ctctttgttt gttttcttga
    38701 ttgccgccat gtaagagggg ggccaacttt aagcctttat tgtataaaaa accagtcccc
    38761 tttggtccat gaaacttatg ggcagaggca gagagcaaat caatccccaa atctgccggc
    38821 tgtattggga ccttgccaat agcttggaca gcatcaacat gaaagacagc ctgatgctgc
    38881 tttagcatgc taccaacagc ctgaataggc agcaaatctc ccgtttcgtt gttagcaaac
    38941 atcatgctga ctaagattgt atcctctctt aaggcagctt ggagctgatt tagatcaatg
    39001 attccatttt tagcctcaag gtaggtcacc tcaaagccaa atcgttcttc cagataggcc
    39061 attgtgctta acacggaatg atgctcaata gcagttgtaa tcaagtgttt gcctttttcc
    39121 tgatgagcta aggcatagcc cttgatagca gtattgttac tttcagtacc tcctgaggta
    39181 aagataatgt ggttttctgc agctcctagg cagttggcaa tagcttttcg gcactctctt
    39241 aattgtttgt ttgcctgccg cccataagca tgaatactag atgggttacc aaaatcatca
    39301 gccatagctt cagtcatcgc cttgatagca gcctgactaa gcgatgttgt agcagcatta
    39361 tcaaaataaa tcatgattag ttagtgcttt caggtttgta agaaaacagt ggacttagtg
    39421 gttttctttc gtgaatgcga atgatagcct ctgcaattaa atcactggca ctaagatagg
    39481 ttactgtttt agggatacga tttttagtct tgacagagtc cgtgacaatg atctctttga
    39541 ttggagcagt ctctaaaata tcagctgcac ctcctgcaaa aatcccatga ctagccactg
    39601 cataaatgtc agttgcgcct gcacattcta ggatcttagc tgcctctgca aaggtttttc
    39661 ctgtgttgag aatgtcatca atcaagatag ccttcttgcc agcaacatca ccaatcacat
    39721 agccttcttc gcgctcagca tcgtcttgtg cataatcgat aatggcaatt ggagagttaa
    39781 gatactctgc taagcttcta gcacgcttga taccagaatt tttagggctg acaataaccg
    39841 tatcaggtcc tgagaggccc agtggataat agtgctttgc aaaaagaggc actgtaaata
    39901 aattatcaac tggaatgtca aaaaagcctt ggacctgaac cgcatgcaaa tcaagggtta
    39961 caacgcgatc aatccctgct ttggtcagca tgtttgcgac cagctttgct gtaataggct
    40021 cgcgagactt tgcaacacga tcctgacgcg aataaccaaa atatggcaaa acaatattga
    40081 ctgtattagc acttgcacgc ttacaagcat caatcatgat gagcagctcc cataggttat
    40141 cgttgacagg aaagcttgtt gattgaatga tataaatatc atcaccacga actgtttctt
    40201 caatgttaat catgatctca ccatcagaaa attgacgaga tgagaccttt ccaagcggaa
    40261 taccagcagc cttagaaatt ttttcagcga ttgcgagatt tgaagtgagt gagaacagct
    40321 tgatttgctt gtcagcatat cgttcagtca tgataaaatt agctccttac attacattaa
    40381 cgatagaata acaggttaac agttattcaa gattacaaat agacagtact attttaacaa
    40441 aaaaacagaa aaatttcagt ctttctgttg attttctgtc ctctcctagg attttttaag
    40501 ggtcttgcta aagcgagcga ccttgctttt ggaatattta aaggtgatct gatgctgggc
    40561 taaaaagtgg tcaaaatcaa cctttcctct tacaggatca gtcacctcta gctcaagctc
    40621 atagtctttg ataccagcat attgattata atccagcgct agcttgccaa taggagtatc
    40681 tgcctctcga cgaatggtag tcaggtttcc gaaggttttt atagcagata ggtcaacgtc
    40741 aagagtgctg ataatatcaa ggatagctga ttttggtagc tgtcctgtct gaatgatagc
    40801 ttttgcttgg gtgtcatcaa gctctaaatt gtactcgcga ttaccaacct tttcagggac
    40861 ttttaaggtt aattcagcag gagcagcaac aaaggtgcga atgcgaagtg acattttatg
    40921 agccttgaga tcaaaatgat cagtatcaat gtaataattt gtctgggtaa ctggtgggac
    40981 atgagtcatt tgagagagga ggcgattata ttcgtccttt gtcagtaagg tcttgtattc
    41041 gatttctagg ttagtcatgc gaacgttcct tttaactata ttttatgcta taataaattg
    41101 ttatcttaat tttatattaa tatccgaggt ttgacaagaa aggagagaaa ggatggcttt
    41161 agattgggaa gaatttttgg atccttatat acaaacggtt ggcgaattga aaattaagct
    41221 gcgcggtatc cgaaagcagt ttcgcaagca aaaccgttat tctcctattg agtttgtgac
    41281 tggacgtgtc aagtcggttg agagcatcaa ggaaaaaatg gccttgcgtg gtgtcttgga
    41341 agaaaatatc gctcaagata ttcaagacat cgctgggctt aggattatgg tgcagtttgt
    41401 ggacgatatt gaggacgttt tgtccttgct tagacaaaga caggacatga caattgttta
    41461 tgagcgagac tacattagaa acatgaaatc tagtggttat cgctcgtatc atgttgtcgt
    41521 tgagtatcct gttgatacca ttgagggtca aaaaaaagta ttagcagaaa ttcaaatccg
    41581 tactttagca atgaattttt gggcaaccat tgagcattcc ttgaactaca agtacggtgg
    41641 tgattttcca gaagaaataa aaaaacgatt agaggttaca gcaaaaattg ctttggagct
    41701 tgatgaagaa atgcgaaaaa ttcgtgaaga cattcgtgaa gcacaattgt tatttgatcc
    41761 tgtaacacgt catttgagtg atggtgtagg aaatagtgat gacacagatg aattatacag
    41821 ataaagtaaa gcgcgttgct atcattgcaa acggcaaata tcagagtaag cgccttgcct
    41881 caaagctttt tggcgtcttt aaggacgatc cgagttttta cctatccaaa aaaaatccgg
    41941 atattgtgat ttcaattggc ggagatggca tgcttctatc agcctttcat atgtacgaaa
    42001 aagaattaga cagggtgcga tttgtaggca ttcacactgg acaccttggt ttttacactg
    42061 attatcgtga ttttgaggtt gatcaattga tagccaatct tagaagagac accggtgagc
    42121 aaatttctta ccctatttta aaggtagtta ttacgcttga tgacggtcgc ctgtttaagg
    42181 ctagggctct caatgaagca actattaagc gtatcgagaa aacgatggtt gcagatatta
    42241 tcattaacaa tgtcaagttt gaaagctttc gtggtgatgg catctctgta tccacaccaa
    42301 ctggaagcac agcctataac aaatccttag gtggagctgt attgcaccca acgattgagg
    42361 cccttcagct aacagaaatc tcgagcctga acaatcgtgt atttagaacc ttggggtcct
    42421 cagtgattat tcctaaaaaa gataaaattg agcttgttcc aaaaagacta ggcgtttata
    42481 ctgtctctgt tgacaataaa acctaccact taaaaaatgt ggttaaggtg gaatatttta
    42541 tcggcaatga aaagattcat tttgtgtcct cacctagcca caccagcttt tgggaaaggg
    42601 ttaaggacgc ttttattggg gatagtgaat catgaggttt gaatttgttg caactaaaaa
    42661 aacaaaggta aagacccttt taaaagagca cgatgtgtca aagggattgc tcgctaagat
    42721 taaatacaag ggtggcaata tatgggtaaa tggcgttgcg caaaatgcca tttatttatt
    42781 ggatattggt gatgtggtgg ctattgatat tccaaatgag gagtcctttg agcaattgac
    42841 agcgatttcg catgaccttg atattgtgta tgaggacgaa cattttctca ttctcaacaa
    42901 gcctgctggc tacgctagca ttccaagtgc tatccattct aatactatag ctaattttat
    42961 caaggcttat tatatcaagc aggactatcc caataaacag gttcatattg tgacgcgctt
    43021 agatcgggat accagtggct taatgctctt tgccaagcat ggctatgccc atgccagatt
    43081 agataagcag ctacagcaaa gagctatcaa taaacgctat tatgctcttg tttgtggtca
    43141 ggagaggctt ccagatcaag gtgagattat agctcctatt ggccgtacgg acgacagcat
    43201 tatcacaaga actgtcacgc caaagggaaa gtatgctaag acaagctaca aggtcattgc
    43261 ccgctatcct gaaaatgtct ctctagtgga tattacgctg cacactggtc ggacccatca
    43321 aattagggta cattttgctc atcttggttt tccacttttg ggagatgatc tgtatggtgg
    43381 tcgattggac cttggcatga ctagacaggc gctgcattgt caccatctta gctttacgca
    43441 cccatttaca gaaagtagaa gcgatcatac aatatgcttg acagatgact ttgagagcgt
    43501 tatcatagat ttacagaaaa aagatagagg ttagttaatg agtattcgta atttatttgg
    43561 tggtttaagg gaaaaaattg tcggcaaaaa catgaagatt gttttccctg agggaaatga
    43621 tgagcgtgtt gtacgtgcag cagcacgtct aaagtttgaa ggtcttgttg agccaattat
    43681 tcttggtcag gcagatgata ttcgcagcct gctaacacag ctaggctttg ctgagcagca
    43741 ctatacaatc attaacccaa atgattatgc tgattttgag aaaatgaaag cagcctttgt
    43801 agagcttcgt aaggtcaagg caacgcttga agatgctgat agactgctta gagatgtcaa
    43861 ttactttggt gttatgctgg ttaagctagg cttagcagat ggcatggttt caggggctat
    43921 tcattcaaca gctgatacgg tgcgtccggc gcttcagatt atcaagacaa agccaggcat
    43981 ttctagaaca tcaggtgtct ttttgatgaa tcgcgaaaat acagagcagc gtttagtgtt
    44041 tgctgattgt gccattaata ttgacccaac tgctcaggag ctcgcagaaa ttgcggtaaa
    44101 cacagcagat actgcgaaaa tttttgatat tgatcctaag gttgccatgc ttagcttttc
    44161 aacaatgggc tctgctaaag ccccacaggt tgaaaaggtt caagaggccg tccgtattgc
    44221 taaggaattg aggccagagc ttgctttaga cggtgagctt caatttgacg cagcctttgt
    44281 accaagtaca gcagcgatca aagcccctga ttcatcagtg gcaggccatg cgaatgtttt
    44341 tgtcttccca gatttacagt ctggaaatat tggctataag attgctcagc gcttaggcat
    44401 gtttgatgct atcggaccaa tcctgcaagg attgaacaag cctgttaatg atttatcacg
    44461 tggctctagt gcagaggata tttacaagct agctattatt acagcagcgc aagcgcttga
    44521 aaatgagtct atcaattaac tgctaatagc cattaagttc acaaggctta gctatagtag
    44581 atgttgctta aaacgagttg gataagccag ctcgtttttt cagaaagtga ggaaggaaat
    44641 gacaaagatt gcattagtaa caggcgcctc tgctggcttt ggtaaagcca ttgcagagca
    44701 gttaatagcc caaaacatca aggtgatcgg agcagcccgc cgcatagaaa agctaagaga
    44761 gctagaaggt atttttggtt ctgagaggtt ttatccgctt caaatggacg tttcagaacc
    44821 aactgccatt gataaagcac ttgcagaatt acctaaagaa tggcaggcca ttgatatttt
    44881 agttaataat gcaggactag ccttaggact tgataaggcc tatgaggctg atgtcgccaa
    44941 ctggctaacc atgattaata ctaatattat tgggcttatc tatttaacac gtcaggtatt
    45001 accgcaaatg gtaagcagca acaatggcat gatcatcaat atcggctcaa ctgctggcac
    45061 tattccctat ccgggagcta atgtttatgg ggcttcaaaa gcctttgtta agcagttttc
    45121 gcttaattta agggcagatt tagcaggaac aaatatcagg gtgaccaata ttgagcctgg
    45181 cctttgtgag ggaacagagt tttctcatgt tcgctttaag ggtgaccatg agcgtgttaa
    45241 agcactttat gcaggtgcac atgctattca gccaagggat atcgcaaata ctgtctcatg
    45301 gattattgat cagccagagc atgttaacat taaccgcgtg gaaatgatgc ctgtctcaca
    45361 aagctatggt tctcagcctg ttagccgtca tgactaagaa ttacaagagc agatgtaaaa
    45421 ggattgtcga agtgcaaccc aaaaagactt aaagcctagc tgttttatag cctggcttta
    45481 agtctttttc tctaattttt cttagaaatg atccgaaaga gaaggtccag atgtgacatc
    45541 tgaccaccca acaatggcct gccctgtttc ttccaaatag tgctgcagca taggcttgaa
    45601 gtccaaaatc atgtcataga ccccaacaaa ttgcttggta tcatcgtaca aggcttgata
    45661 ttgctgcata taaatatgat cctgtgaagc agtcggaata agatacagct tactgccagt
    45721 tgccgccttg tgcaaatcag tcaagatcca atcctcaatg acatcatgct tatcagaagc
    45781 aaaaaaattg ccattaaagc gatgattatc aaagatgatc tgcccctgat gatcagcaat
    45841 tctagcctga aggggaagat aggttaaaaa atgtggggct aaggcttggt aaaattgcat
    45901 gaggtattta gcaagtctta aagtttgctg actatcagta aaggtatgat cactaacggt
    45961 aaatccttgc tctttgtctg cctgattaaa ataaagtaca ggtagtgagg cttcaaggtt
    46021 ctgaaaggta aaaatggcct gagccttttt gagctgctca gtagtcagct gacggacaat
    46081 agtgatatga aacagatagc taaactcttg tgataaggtg gtaaaaaaag tcttttgcag
    46141 attattctta tcatcaacca gtgctaaggt ataaatcgtt ttagtcataa ggctatcata
    46201 gctttatttt gtttaaatag caatgaaaca gccttttagt ctacagactt agttgatagc
    46261 ttaataaaag aaagcaatat gaaaaaatga ttaaagcaaa ctagttgact tgttagttta
    46321 aactttttat aataaatcaa atgagaagat aatatgaggc ttagcctaag ctgctgagct
    46381 tatctgataa tcattcttct tagcactgag ataaccccct ttatcgatta attggagaat
    46441 ctatgatacg ttttaataat gtttccaaaa cctttggtca caccaaggtg ctgcaggagc
    46501 aaagttttca aatacagaat cgcgaatttt ttgtgctggt cggtccaagc ggctctggca
    46561 aaacaaagct cttaaaaatg atcaattgcc ttactgaacc aagctctggc gaaattctat
    46621 taaacggaag gccacaaaaa gagctagatt tgcgagatat gcgcttatct attggctatg
    46681 ttcttcagca aattgccctg tttccaaacc ttacagttgc tgaaaatatc gctattattc
    46741 cagagatgaa gaagtggtca gacaaagaga ttagaactaa gacagaggaa ttgttagata
    46801 aggttggatt gcctgcaagg gattatctaa atcgctatcc cagtgattta tccggtggag
    46861 agcagcagag gattggtatt gttcgtgcca tcatttctca ccccaaggtg ctgttaatgg
    46921 acgagccgtt ttcagccttg gatcctattt cacgcaagta attacaggac ttgatgttaa
    46981 gtcttcacaa ggagtttgat atgacaattg tctttgttac tcatgatatt gatgaggcta
    47041 tcaagcttgg agatcgtgtg gctgttttaa atgaagggca aattgttcaa ctggatcgac
    47101 cagatgcgat catagctgcg cctgctaatg attttgtagc aagtctattt ggaggtcgtg
    47161 attatgccta gtttactgat gaccttttgg gatcgttttg gtgattgggc aagggcatta
    47221 ggagagcact tgcagatttc tcttctttct ttgctggctg ccttgctgat aggcattccg
    47281 cttgcagctc tgttgagtaa aagtaagcgc tggtcaaata tcatcttgca gctgacaggt
    47341 gtttttcaaa ccattccttc cctagccttg ttgggactat ttatccctct aatgggaatc
    47401 ggaactgctc cagctgtaac agctttggtt atttatgcca tatttcctat tttacaaaat
    47461 acgattactg gcttaaatgc tattgatcca agtcttgtag aggccggaac agcctttgga
    47521 atgaccaagt gggagcgact gaaaatattt gaaattccta ttgctatgcc agttattatg
    47581 tcaggtgttc ggacctcagc agtgatgatt attggaacag ccaccctagc ttctttgatc
    47641 ggagctggcg gcttagggac ctttatccta ttaggaattg accgtaataa tgctcagctg
    47701 attgtgattg gtgctgtgtc gtcagccttg cttgcgatag tgtttaacag tcttttgtga
    47761 taccttgaga aggcctcact gaggcgtatt gcgataagct ttgctgcgac cttattactg
    47821 ctcttaattt cctatactcc aatgtttgtc aagcggtttg ttaatcagtc aaatactctg
    47881 gtgattgctg gcaagctagg agtagagccg gatattttga tcaatatcta taaagagctg
    47941 attgaagacc agtccaagct taaggttgaa ttgaaaccta attttggcaa gacaagcttt
    48001 ttatacgagg cgattaaatc aggagatatt gatatttatc cagaatttac aggaaccatc
    48061 acctctagcc tattaaagaa aaagcctaag ctttctaatg accctaatca ggtttactta
    48121 gctgctaagg aggggattgc tgagcaggat cagttgacgc ttttaaagcc ctttgcctat
    48181 caaaatacct atgcagtggc gatgcctgaa aaaatagctg acgaatttaa cattcaaagt
    48241 atttcagatg tgaagaaata tgaaaaacag ctaaaggctg gttttacact agaatttaag
    48301 gatagagagg acggctataa gggcatacag gataagtatg atctacattt atcagttgca
    48361 acgatggagc cagctcttag gtaccaagcc attcagtcag gaaacattca gctgacagac
    48421 gcttattcaa ctgatgctga gatcgtgaaa tatcagcttc gagtcttaaa ggacgataag
    48481 cagctctttc caccttatca aggagcgcca ttgatgaagg cttccttact aagaaagcac
    48541 cctcatctca aaacgattct caatcagtta tcaggaaaga ttactgaaga ggagatgcaa
    48601 gcaatgaact atgaggtgtc cgtaaagggc agagcagcta gccttgtggc acatgactac
    48661 cttgtaaagg ccggtcttat tgcaagaacc aaataagcag gcatgctagt cttattctgg
    48721 actggcatgc tttatttatg tgatttttag tctgtctggc tctgcaaggt gtgtgccaaa
    48781 taaccgctcg tttgatgtgt ggttattgat ttagtagcta aggattggaa tcttaaaata
    48841 aaatccgaac gtttgtctaa aaaaagcttt aaaaattgac aaaacataaa cgaaaggata
    48901 aaataaatta aggaaaggta acattttacc tagcgatgcc tcggacaagc ttgaggtcat
    48961 aggaaggtca ttttatatag aagcttatgt cagctgcaga tcagggaagt ccttgctgga
    49021 ttagtagctg aatgttgaaa aaggagagaa atgatgttta atgacatgcc tgtatttgat
    49081 tatgaggata ttcaattaat tcctaacaaa tgtatcatca atagtcgttc agaagcagat
    49141 acgagtgtaa gacttggtaa ttataccttt aagctacctg ttattcccgc caacatgcaa
    49201 accattattg acgaaacaat tgcagagcag ttggcaagag atggttattt ctatattatg
    49261 caccgctttg atgaggaggg gcgcaagccc tttatccagc gtatgcatga gcaacagctc
    49321 atcgcctcta tttcggttgg tgtaaaggat tatgaatacg atttcgtctc ttctttgaag
    49381 gaggacgcac ctgagtttat cacgattgat attgctcatg gccatgctga tagtgtgatc
    49441 aaaatgatta agcatattaa ggctgagctg cctgagacct ttgttatagc tggaaatgtc
    49501 ggaacaccag aggctgttcg agagctcgaa aatgctggtg ctgacgcaac aaaggtcggg
    49561 attgggcctg gtaaggtttg tatcacaaag gttaagacag gctttggaac aggggggtgg
    49621 caattagctg ctgtacgttg gtgtgctaag gctgctcgta agccgattat tgctgatggc
    49681 ggtattcgta ctcatggtga tattgccaag tcgattcgat ttggggcaac aatggtgatg
    49741 atcggttcac tctttgcagg tcatattgaa agcccaggca agatggtaga aatcgacgga
    49801 cagtccttca aggaatatta tggctctgcc tctgaatatc aaaaagggga gcataaaaat
    49861 gtcgaaggca agaagatttt gcttccaacc aagggtcatc tagctgatac tttaaccgaa
    49921 atgaagcagg atttacagtc atcaatctca tatgctggag gcagagattt ggagagcctg
    49981 cgtcgtgtga attatgttat cgtgaaaaat tctatttgga atggtgactc tatttaaagc
    50041 cttggctaaa gacctagtct aaataaggat aagcaagctg attgatgctg agaataagca
    50101 cagcgtgtct ataggacgcc tgaatgtcta gtagccagta aagcttttag gcttgctgat
    50161 tggataggtc attgtgccta tgtgcagcag ggctctaggg acttagataa aaaggagaca
    50221 tgatgaggtt actggaggag cgtatcctag ctgatggaac tgttttaggt gagacgattt
    50281 tgaaggtgga tcaattttta acacatcagg ttgactatcg cttgatgaag gaaatcggta
    50341 gagtatttgc tgatcaatat gctgatttgg gcattaccaa ggtggtcacc attgaagcct
    50401 ctggtatcgc accagcagtt tataccgcag aagctcttga ggttccgatg atttttgcca
    50461 aaaagcacaa aaatatcacg atgacagagg gaattttaac agcagaggtt tattccttta
    50521 ccaaacaagt gacaagtact gtttctattg caggaggact gctatcaaaa gaagataggg
    50581 ttttgattat tgatgacttt ttggctaatg gtcaagcggc aaaaggcttg attgatatca
    50641 ttcatcaagc aggggccaaa gctgttggca taggcattgt cattgaaaaa tcttttcagg
    50701 ctggacggca attgcttgag gatttgggag tagaggtcac ttcattggct cgtattaagc
    50761 attttgacaa tggaatagta agctttttgg aggctgatgc ctgatgactg cttcttatct
    50821 ctcagcatta agctttttac ttgtatagct ataccagctt tatttcagta gctattggct
    50881 ggtgataagg gatattggta tggcggtgca ttacggcgag ccgtgggcag ttgcccttgc
    50941 ggctttacga tttagtatag actatcaaga attgactgct tcctttttat cgagatgaat
    51001 cattagacag acaatcatga tttggcgtga aggctgcttt cagtaaacat tacatcatca
    51061 aaaatcagct aggtattcac ttagctgatt tttagtgctt ataatgtagc cgaaaggctc
    51121 cctttaaccc gtctgagata gtaacctgac catctttggt aatgataatg ccttccacct
    51181 caggcagctt atttagctga cttaggacaa aggaatgctc taagccaaaa agacgactac
    51241 tccatagctc accatcaagt gagaattggc tgacaatggt taggctagcc atattggtct
    51301 tgataggata gccgttgtga ggatcaagaa ggtgatgata agttttgtct ttgatttgta
    51361 attgtctctc gccgattcct gaggttacta cagatttatt gttaacctta atcacgccga
    51421 catgctgtcc tcttttttga ttggtctgct ggatcccaac gtaaaacaag ccattatgtc
    51481 gttgcttgtt ggtgccatgc acaaggacat ttccacctag attgataaga gcagcagtga
    51541 taccgtcttt aataagaaat gccatgagct tatcagcaat atagcccttt gctagggcac
    51601 ctaagtcgat agacatgccc ttttctttca aaaaaatact tccaaggctt tgatctaa
//
LOCUS       DARYMD010000007        50720 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYMD010000007 DARYMD010000000
VERSION     DARYMD010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50720
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            175..963
                     /locus_tag="TU818_000365"
     CDS             175..963
                     /locus_tag="TU818_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0923223.1"
                     /translation="MARGRGRLTPQEIEALGFFSSKFNDLLNETNTKQVELSKATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATDQLKEQKNKMTSMEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYEEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGVYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYKDKFAPFSEDPRIIGKIVGNFMPKEY"
     gene            972..2141
                     /locus_tag="TU818_000366"
     CDS             972..2141
                     /locus_tag="TU818_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEL0923224.1"
                     /translation="MGLFNFGKIKDVALEKKLQKLQQKIENEKEKLREIKEEIALAND
                     TLDLQEYGFFERQYKFSHSTKYKDALDTLRMKQKTLIKNGEATSIISPMTLDGSAAKG
                     KAMQNQLRKAAIRGFNGEADALLVKVSVVNVDKKVQTLQKAFEQLNKMYERNLIQLTF
                     KYLDLKAQELRLAAEYELQKQEEKEILREQRAREREDKKLQAEITAKRKQLEKDRKHF
                     LQMVKNVEVMLANASPKEQEKLQLQLIEYQNKLSELDKIEEDIDYREGHATAGYVYVI
                     SNIGAFGEDVYKIGVTRRLDPMDRIRELGSASVPFTFDVHALIFSEEAFALESELHNK
                     FEAYKVNKINSRKEYFRVPFAKIKEVLENHKELAIEITEEAEAFEYRQSILKNGG"
     gene            2144..2347
                     /locus_tag="TU818_000367"
     CDS             2144..2347
                     /locus_tag="TU818_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923225.1"
                     /translation="MKWLFLILFIGCGANAVNLSKKVNSDDEVDENNSHLISHSNEEI
                     PWNKKEQLYWGTASIVFLVLFII"
     gene            2479..3912
                     /locus_tag="TU818_000368"
     CDS             2479..3912
                     /locus_tag="TU818_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL0923226.1"
                     /translation="MITTRKVAIYVRVSTTNQAEEGYSIQGQIDSLIKYCEAMGWIIY
                     EEYTDAGFSGGKIDRPAMSKLITDAKHKRFDTILVYKLDRLSRSVRDTLYLVKDVFNQ
                     NNIHFVSLQENIDTSSAMGNLFLTLLSAIAEFEREQITERMTMGKIGRAKSGKTMAWT
                     YTPFGYDYNKEKGELILDPAKAPIVKMIYTDYLKGMSIQKIVDKLNKMDYNGKDCTWF
                     PHGVKHLLDNPVYYGMTRYNNKLFPGNHQPIITKELFDKTQRERQRRRLGIEENHYTI
                     PFQAKYMLSKFLRCRQCGSRMGLELGRPRKKEGKRSKKYYCLNSRPKRTASCDTPLYD
                     AETLEDYVLHEIAKIQKDPSIASRQKHIEDHELKYKRERIEANINKTVNQLSKLNNLY
                     LNDLITLEDLKTQTNTLIAKKRLLENELDKTCDNDDELDRQETIADFLALPDVWTMDY
                     EGQKYAVELLVQRVKVDRDNIDIHWTF"
     gene            complement(3942..5111)
                     /locus_tag="TU818_000369"
                     /pseudo
     CDS             complement(3942..5111)
                     /locus_tag="TU818_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            5167..5808
                     /locus_tag="TU818_000370"
     CDS             5167..5808
                     /locus_tag="TU818_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL0923227.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GVKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLEQEALIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAN"
     gene            5929..6855
                     /gene="cysK"
                     /locus_tag="TU818_000371"
     CDS             5929..6855
                     /gene="cysK"
                     /locus_tag="TU818_000371"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL0923228.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVLIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIAVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEESSP
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(7242..7604)
                     /locus_tag="TU818_000372"
     CDS             complement(7242..7604)
                     /locus_tag="TU818_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL0923229.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(7604..9004)
                     /locus_tag="TU818_000373"
     CDS             complement(7604..9004)
                     /locus_tag="TU818_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0923230.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKNTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLQADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     KWANAVGIDYGMAGRHEAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPVELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLRPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLAGHEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEELYNLRGALSMANAGPNTNGSQFFIVQNTSLP
                     YSQKELERGGWPKDIAAAYAEHGGTPYLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIEAIEVFD"
     gene            complement(9037..9678)
                     /locus_tag="TU818_000374"
     CDS             complement(9037..9678)
                     /locus_tag="TU818_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0923231.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALELRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPNLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            complement(9671..10675)
                     /locus_tag="TU818_000375"
     CDS             complement(9671..10675)
                     /locus_tag="TU818_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0923232.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIVQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLQQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMGQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            complement(10672..11364)
                     /locus_tag="TU818_000376"
     CDS             complement(10672..11364)
                     /locus_tag="TU818_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL0923233.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYVIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGEAEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            complement(11497..13392)
                     /gene="pknB"
                     /locus_tag="TU818_000377"
     CDS             complement(11497..13392)
                     /gene="pknB"
                     /locus_tag="TU818_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL0923234.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSSVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAVDARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            complement(13389..14129)
                     /locus_tag="TU818_000378"
     CDS             complement(13389..14129)
                     /locus_tag="TU818_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL0923235.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVHEGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            complement(14167..15489)
                     /gene="rsmB"
                     /locus_tag="TU818_000379"
     CDS             complement(14167..15489)
                     /gene="rsmB"
                     /locus_tag="TU818_000379"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL0923236.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARAHGRGADKLVNAVLRQLTNKPLPDIKSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAIMESLFVRSRASIRVTDLTKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            complement(15479..16414)
                     /locus_tag="TU818_000380"
     CDS             complement(15479..16414)
                     /locus_tag="TU818_000380"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL0923237.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLEKPAYDILAVVTQPDRAVGRKKD
                     ITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            complement(16481..18865)
                     /locus_tag="TU818_000381"
     CDS             complement(16481..18865)
                     /locus_tag="TU818_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL0923238.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSSQSTQQLKAIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTADLAAADLADVFSNGDSLLYSKLSPEQEGRVLRLIQSGKIR
                     ATYLAKDKKTIKTETYYQVNRLALQEHKISNRAKKRQALKAYLLANPQKDKLAKLYQD
                     YSREVVSYFVTNQLIELEERRVNRSEDYFNHIKAAPLLKLNQQQQQAVDQITKAVGRE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQMTSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALIRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTLHMDTKTMNCHYCGFQRAIPKLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILSQFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGIRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQLLTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            complement(18929..19246)
                     /locus_tag="TU818_000382"
     CDS             complement(18929..19246)
                     /locus_tag="TU818_000382"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL0923239.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGAAPTQSFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARIEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(19271..19897)
                     /gene="gmk"
                     /locus_tag="TU818_000383"
     CDS             complement(19271..19897)
                     /gene="gmk"
                     /locus_tag="TU818_000383"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL0923240.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            complement(20059..21669)
                     /locus_tag="TU818_000384"
     CDS             complement(20059..21669)
                     /locus_tag="TU818_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL0923241.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAKADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQSSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIRELRAIDYAK"
     gene            21826..22311
                     /locus_tag="TU818_000385"
     CDS             21826..22311
                     /locus_tag="TU818_000385"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL0923242.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKI
                     ITSSLEEIATSITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            complement(22456..23907)
                     /locus_tag="TU818_000386"
     CDS             complement(22456..23907)
                     /locus_tag="TU818_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923243.1"
                     /translation="MSEKSKAFESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPAGETSFIEPLAARADTSAAATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTN
                     KTKANAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFTTAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPQVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFKPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(23921..25075)
                     /locus_tag="TU818_000387"
     CDS             complement(23921..25075)
                     /locus_tag="TU818_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL0923244.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVR
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRVEKGGAPIKENMAAAILKLSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKRNA
                     EEAGLADIITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMVQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            complement(25139..25507)
                     /gene="rnpB"
                     /locus_tag="TU818_000388"
     ncRNA           complement(25139..25507)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TU818_000388"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(25520..25843)
                     /gene="gpsB"
                     /locus_tag="TU818_000389"
     CDS             complement(25520..25843)
                     /gene="gpsB"
                     /locus_tag="TU818_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL0923245.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            complement(25965..26480)
                     /locus_tag="TU818_000390"
     CDS             complement(25965..26480)
                     /locus_tag="TU818_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL0923246.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIERDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRETDF
                     VKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            26556..27164
                     /gene="recU"
                     /locus_tag="TU818_000391"
     CDS             26556..27164
                     /gene="recU"
                     /locus_tag="TU818_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL0923247.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            27151..29316
                     /locus_tag="TU818_000392"
     CDS             27151..29316
                     /locus_tag="TU818_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0923248.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKKLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSDDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     ASSQSSDEDTTEDSHSEANDSTTSSSEQQSSSTDDKKTN"
     gene            complement(29359..30693)
                     /gene="pepC"
                     /locus_tag="TU818_000393"
     CDS             complement(29359..30693)
                     /gene="pepC"
                     /locus_tag="TU818_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL0923249.1"
                     /translation="MSVLTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSE
                     IDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWD
                     KYEKSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESVSSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNL
                     GLPPRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSY
                     TVDMLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALN
                     TYDFQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVG
                     DKGYFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAK"
     gene            complement(31382..32206)
                     /gene="nadE"
                     /locus_tag="TU818_000394"
     CDS             complement(31382..32206)
                     /gene="nadE"
                     /locus_tag="TU818_000394"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL0923250.1"
                     /translation="MTLQEDIIRQLEVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQKALAFIQ
                     PDQALTVNIKEAVDGQLRALEAAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKVLKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
     gene            complement(32203..33663)
                     /locus_tag="TU818_000395"
     CDS             complement(32203..33663)
                     /locus_tag="TU818_000395"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL0923251.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGTMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNDLEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            complement(33939..35333)
                     /locus_tag="TU818_000396"
     CDS             complement(33939..35333)
                     /locus_tag="TU818_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL0923252.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGVFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVAVGVSALINILPGVADAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCKKALKG"
     gene            complement(35453..36370)
                     /gene="trxB"
                     /locus_tag="TU818_000397"
     CDS             complement(35453..36370)
                     /gene="trxB"
                     /locus_tag="TU818_000397"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL0923253.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYDTKT
                     VIVATGAKHRLLGVAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTSHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGAIAGQGVYHYIESLSS"
     gene            complement(36430..36657)
                     /locus_tag="TU818_000398"
     CDS             complement(36430..36657)
                     /locus_tag="TU818_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL0923254.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            complement(36767..37510)
                     /locus_tag="TU818_000399"
     CDS             complement(36767..37510)
                     /locus_tag="TU818_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0923255.1"
                     /translation="MIKVTHLTKSFSGQKILDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSITIDDFAVDFEHITKEDILTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGAPEQIFRHPKEARTKEFFANYAKTYI"
     gene            complement(37510..38313)
                     /locus_tag="TU818_000400"
     CDS             complement(37510..38313)
                     /locus_tag="TU818_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0923256.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLFLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASIFAITAFAFNEAAYTSETIRAAIQSVHTGEIEAAKS
                     LGMTSAQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYNMAIKAPIPTNNSKIGELR"
     gene            complement(38690..39517)
                     /locus_tag="TU818_000401"
     CDS             complement(38690..39517)
                     /locus_tag="TU818_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL0923257.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKKHSVTGYDIEVLKRVFKGSKKYRLSIEVVPFPSILAGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPFTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
     gene            40025..40480
                     /locus_tag="TU818_000402"
     CDS             40025..40480
                     /locus_tag="TU818_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923258.1"
                     /translation="MKKAIVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRK
                     QPVIKYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGG
                     YWSILEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
     gene            complement(41121..42464)
                     /locus_tag="TU818_000403"
     CDS             complement(41121..42464)
                     /locus_tag="TU818_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0923259.1"
                     /translation="MSFHDYHFKHYIQEALDELGFVEPTEVQQRLIPIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(42547..43554)
                     /locus_tag="TU818_000404"
     CDS             complement(42547..43554)
                     /locus_tag="TU818_000404"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL0923260.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTFQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            complement(43556..45811)
                     /locus_tag="TU818_000405"
     CDS             complement(43556..45811)
                     /locus_tag="TU818_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0923261.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKIKGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYQLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            complement(45815..46138)
                     /gene="ftsL"
                     /locus_tag="TU818_000406"
     CDS             complement(45815..46138)
                     /gene="ftsL"
                     /locus_tag="TU818_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL0923262.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            complement(46142..47092)
                     /gene="rsmH"
                     /locus_tag="TU818_000407"
     CDS             complement(46142..47092)
                     /gene="rsmH"
                     /locus_tag="TU818_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL0923263.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQRAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            complement(47195..47611)
                     /locus_tag="TU818_000408"
     CDS             complement(47195..47611)
                     /locus_tag="TU818_000408"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923264.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLGDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            complement(47631..48878)
                     /locus_tag="TU818_000409"
     CDS             complement(47631..48878)
                     /locus_tag="TU818_000409"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL0923265.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEILCDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALYSNMALVRLI
                     RNALEASAITPDAVLLVEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            complement(48878..49696)
                     /gene="proB"
                     /locus_tag="TU818_000410"
     CDS             complement(48878..49696)
                     /gene="proB"
                     /locus_tag="TU818_000410"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL0923266.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            50297..>50720
                     /locus_tag="TU818_000411"
     CDS             50297..>50720
                     /locus_tag="TU818_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923267.1"
                     /translation="MVKLSKRSKIAMSFLIVFCGIFFVAQKRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGNVTYHPTADYAFTSSGVSPDYYFTSTA"
BASE COUNT        14990 a        11590 c         9688 g        14452 t
ORIGIN      
        1 ctcctttggg agtctttatt ttgcttaatt ctttaagctt gattatatta taattcgaat
       61 taaaacgtat gtcaatagca tttacgaaaa aaatcgtatt tattttaaaa atactattta
      121 caaatacgat ttaaagcgat atcatatgag tataaaaatc gaaaggaaaa taatatggca
      181 agaggaagag gtagattaac acctcaagaa atagaggcgt taggattctt ttcgagcaaa
      241 ttcaatgatc tgctcaacga aacaaataca aagcaagttg aactctcaaa ggctacagga
      301 ataccaccaa gtacgctcac aggttacgta aaagggacat ctttacctat tcccggtaat
      361 gtccaaaaaa tagccgatta ttttgggtta atgaaatcag atatagatcc aagatttgca
      421 cctcgtaaga aaaatcacga acttaagatt cctacttctc cacttgtcaa aaaaataacc
      481 acaactgtcg tggaattaaa tgttcctcgt aagcaaaaag ttttagactt tgcaacagat
      541 caattaaaag aacaaaaaaa taaaatgact tctatggaga aaaaactcta tgagtataaa
      601 gtttacgaga agctttcagc tgggacaggt tatggatatt ttggtgacgg gaactatgat
      661 actgtctttt acgaagaaga attagactac gatttcgctt cttgggtttt cggcgattct
      721 atggagccca cttatttaaa tggtgaagtt gtgcttataa agcaaactgg ctttgattac
      781 gaaggcggtg tctatgctgt tgaatgggac ggacaaacct atattaagaa agtttatagg
      841 gaaaaagatg gattaagatt agtttcttta aataaaaaat acaaggataa gtttgctcct
      901 tttagcgaag atccgcgtat aatcggcaaa atcgtcggca actttatgcc caaagaatat
      961 tgaggtgtgt tatgggattg tttaatttcg gaaaaataaa agatgtggct ctagaaaaga
     1021 aattacaaaa gttacaacaa aaaattgaaa atgaaaaaga aaaattgagg gaaattaaag
     1081 aagaaattgc attagccaat gatacattag accttcaaga atatggtttt tttgaacgcc
     1141 agtataaatt ttcccatagt actaaatata aagatgcttt agatacgtta cgaatgaaac
     1201 aaaaaacact cataaaaaat ggtgaagcta caagcataat ttcccccatg actctagatg
     1261 gtagtgcagc aaaaggtaaa gcaatgcaga accaacttag gaaagctgca atccgcggct
     1321 ttaatggtga agccgatgcc ttactagtta aagtgtctgt cgtaaatgta gataaaaaag
     1381 tgcaaactct tcagaaggct ttcgaacaat taaataaaat gtatgaaagg aacttgatcc
     1441 aacttacctt taaatattta gatttaaaag cacaagaatt gagattagct gctgaatacg
     1501 aattgcaaaa acaagaagaa aaagaaattc taagagaaca gcgtgcaaga gaaagagaag
     1561 ataaaaaact tcaagctgag attactgcta aaagaaaaca acttgaaaaa gacaggaagc
     1621 actttttaca aatggtcaag aacgtcgaag tgatgcttgc taacgcttct ccgaaagaac
     1681 aagagaaatt acaattgcaa ttaattgaat accaaaacaa gctctcagaa cttgataaga
     1741 ttgaagaaga cattgattat agagaaggac atgcaacagc tggatatgtc tatgttattt
     1801 ctaatatagg tgcttttgga gaagatgttt ataaaattgg agtaacaaga cgtttagacc
     1861 caatggatcg tattcgcgaa ttggggagtg catcggtgcc ttttactttt gatgttcatg
     1921 cgcttatctt tagtgaggaa gcttttgctt tagagtctga gttacataat aaatttgaag
     1981 cgtataaagt aaataaaata aacagtcgaa aagagtactt tagagttccg tttgctaaaa
     2041 tcaaagaagt tctagaaaat cataaagaat tagctattga gattaccgaa gaagctgaag
     2101 cgtttgaata ccgtcaaagt atcttgaaaa atgggggtta aatatgaaat ggttattcct
     2161 aattttattt ataggctgcg gtgctaatgc tgtaaacctt tctaaaaaag ttaattccga
     2221 tgatgaagtt gacgaaaaca acagtcacct tatatcacat tcaaatgaag agattccttg
     2281 gaataaaaaa gaacagcttt attggggcac tgcttccatt gtatttttag tgctttttat
     2341 aatctaaaca caataataaa aagcctcacg ctcaactttg gtcgatgcga gcgtgaggcg
     2401 aacgtgtata gtaaaaacct gctttgcagt aggtctcttt actataccca ttttaacata
     2461 aaaatgaggt gaaaaacaat gattacaaca agaaaagtcg ctatttatgt tagagtcagt
     2521 acaacaaatc aggcagagga gggctattca atacaaggtc agatagacag tttgatcaaa
     2581 tactgcgaag ctatgggttg gattatatat gaggagtaca ctgatgctgg cttttcagga
     2641 ggtaagatag accgtcccgc catgtctaaa ctaattacag acgcaaagca taaacgattt
     2701 gatacaatct tagtttataa gctagacaga ctctcccgaa gtgtcagaga tactctttac
     2761 ttagttaaag atgtttttaa ccaaaacaat atccattttg tcagtctgca agaaaatatt
     2821 gacacttctt cggctatggg taatctattc ctcacattgc tatctgcaat tgccgaattc
     2881 gaacgagaac agataacaga gagaatgaca atgggaaaaa tcggaagagc aaaatccgga
     2941 aaaactatgg cctggactta tacccctttt ggctatgatt acaacaaaga aaaaggcgaa
     3001 ttgattttag atcctgcaaa agcgcctata gttaaaatga tatatacaga ttatctcaaa
     3061 ggtatgtcta ttcaaaaaat agtggataaa cttaataaga tggactacaa cggtaaggat
     3121 tgcacttggt ttccacatgg tgttaagcat ctattagata atcctgtcta ttatggtatg
     3181 acaaggtata ataataaatt attccccgga aatcatcaac caattattac aaaagagcta
     3241 tttgataaaa cccaaagaga aaggcaacgc agaagattag gaatcgaaga aaaccactac
     3301 acaatacctt ttcaggcgaa gtatatgcta agtaaatttt taagatgtcg tcaatgtggc
     3361 tcaagaatgg ggcttgagct tggcagacca agaaaaaaag aaggcaaaag atccaaaaaa
     3421 tactattgcc taaatagtag gccaaaacga acagctagtt gcgacacacc actttacgat
     3481 gcagaaacct tggaggatta tgtgttacac gagatagcca aaatacaaaa agatccgtca
     3541 atagcgagca gacaaaaaca tattgaggat cacgaattaa aatacaagcg tgaaagaatt
     3601 gaagctaata tcaataaaac agtgaatcaa ctctctaagc taaacaatct ttatcttaac
     3661 gatctgataa ctcttgaaga cctcaaaact cagacaaaca ctcttatagc taaaaaaaga
     3721 ttgctagaga acgaactaga taaaacttgt gataacgatg atgaacttga cagacaagaa
     3781 accattgctg actttctcgc cttgcctgat gtatggacca tggactatga gggtcaaaaa
     3841 tatgctgttg agctgcttgt tcaacgtgtt aaagttgata gagataatat agacattcat
     3901 tggacttttt aatgccaaaa attacaaagt tttcaaccct tgatttgaat aagactgctg
     3961 cttgtgtaaa ggcgatgatt ggctaataag acaaagacat ctacggttgg aaaggtcaca
     4021 cctctttcca aaatggttgt tgatataagt atagtgattt gtccttgtct gaattgctca
     4081 atgatagcca ttcgatttga tgactgactg gaagcatgag caatagtttc cttaggaaaa
     4141 tacttgtgga gcagctgaca gcattgctca gccagctcaa taatcggaaa aaagattaaa
     4201 agaggatagc cggttgccct ttgttttttg actagggtga tgaaccttct aggcaatttc
     4261 ccacgattga tagcctctaa aagggagaat aatctttgat actttggaac aactaagggc
     4321 ttgccatgga atcttcttgc caacgtcaat ttgacaagct ctttttgctt gaccttgcgc
     4381 tctaaatctc ttgtagaggt tgctgttagg tatactgtca ctgcatctgc ttttgcagcc
     4441 tgatgagcag catggtttaa ttgacgatta ttgacaaagg ggaaggcatc tacttcgtca
     4501 ataatgagca gatcaaaagc atggtaaaag gtcatcaatt gatgtgttgt ggcaacgata
     4561 atggggcttc tatgataaac ctctgactca gcatgcataa ggcagacttg acaggaaaag
     4621 tcccgcgata gtcgtttttc aagctctatg caaacatcaa ctcgtggact agcaatgcag
     4681 acccagccac ccttattaac aactgctgca atagcttcat acatcatctc tgttttgcca
     4741 gcaccagtaa ccgcatgaac taaggtgtct tgcttgagct taacatggtt agtaagctga
     4801 tgagagatag ctgcctgata tgtcgtgagc tgtccttgcc acctcagata atgtcccttt
     4861 ggaaaagaag ccggtggaaa atagagcaag gggcgatcag attggtttcg accaaaaaca
     4921 agacaggctc tacagtagta agcaccgcta ggcagctgat gagccttctc aattaaactg
     4981 ctacagcgtt ggcagtataa cgttcccttt ttagtgatca tgctttgtaa gctgcaagcc
     5041 caggcagaaa cagcctttgg gcattgcctt tcgggtaaaa gacgtccata gtaattttcg
     5101 atattctcca taccttatta tccgaattat tttgctaaat atcagcattt tttgtaaaat
     5161 tttcttatgg aagattataa aactattatg actgatgggc tttttgagga aagcatcaaa
     5221 aaatctcgct ttatttgcca aatcaaacgc gtctacacag aagaggaggc cagagccttt
     5281 attgctgaca tcaaaaaaaa gcactataag gccaatcatt cctgctctgc tatgattatc
     5341 ggagacaaag gacaaaccaa gcggtcaagc gatgatggtg agccatctgg tactgctggt
     5401 attcccatgc tatctgtctt agaaaggcag gaattaacca atcttgtagc tgttgtgaca
     5461 cgctattttg gaggtgttaa attaggagct ggagggctca ttcgcgctta ctccggcgta
     5521 actgcggcag ctattcaggc cttaaaggtc gttgaggtaa aaaaacaaac tggactagca
     5581 atcagcctca cctaccctca ataccaaatc tatcctaatt ttctggagca agaagcattg
     5641 attgaaatga ataccgaatt ttctgatgtc gtcagaacag ctatttactt tgatcctgag
     5701 cgcttggaga gtatttctaa ggcattgatt gagcattatc atggcaaggt ttcctttgaa
     5761 gagatcgaat cgcaaaggat tgaggtccct gttttgcctg ccaattagca tgaacagtga
     5821 tagcgtctct ttatcactac gatagtaaat ggctatttta ctttgtcgat tattagctat
     5881 atacttttat ataagcatgt attgatacaa ggataaaaag gaggacctat gtcaaagcta
     5941 tatcacaaca ttacagagtt ggttgggaaa acccctatta ttaaattgag aaacaccagt
     6001 ccagaggagg ctgccgatat ttatgtcaag ctagaagctt ttaatccagg ctcttcagtt
     6061 aaggatcgca tagcacttgc aatgattgaa gctgctgaga aagcaggcat gatcaagcca
     6121 ggtgatacaa tcgttgagcc aaccagtggc aatacaggga ttggcttatc ctgggttggg
     6181 gctgcaaaag gctaccgagt gctcattgta atgcctgaga caatgagtat tgaaagacgt
     6241 caaatcattc aagcttacgg agcagagctc gttttaaccc caggtagtga tgggatgaaa
     6301 ggtgcgattg ctaaagcaga agagattgcc agagagaccg gtgcttggat gccctcgcaa
     6361 tttgacaatc ctgcaaatcc caaggttcat gaagagacaa cagggcaaga aattatcgcg
     6421 gtttttggag aaaaaggact tgatgccttt gtttctggtg tgggaactgg tggcactatt
     6481 tctggcgttg cgcatgcctt aaaggctgtt aatcctgata tttctatcta tgctgtggaa
     6541 gcagatgaat ctgccgtctt atctggtgaa gagtcttctc cgcacaagat tcaagggatt
     6601 tcagctggct ttatcccaaa taccttagat acaaaggcct atgaccacat cattcgagta
     6661 gcgtcagagg ctgcccttgc cactgctcgg tcaatcgggg ctaaggaggg ctttcttgta
     6721 ggcatttctt ctggagccgc tgtttatgct gctatccaag ctgctaagga gcttggaaaa
     6781 ggtaaaaagg tcttagctat attaccagat aatggtgagc ggtacctgtc tactgccctt
     6841 tatcagtttg attagaataa tcatataagc accagcccta gcagctagaa taagctttca
     6901 agcataaatc atcgctctta cttagtcacc attaaaggcc agtcagctag catatggaaa
     6961 aatgcttact ttgattcctt tttaacaata aacatagcat accacgccta agcgccccag
     7021 agcttctagc ttcttggaaa taggctttcc tagccgcttt caccacagta aaaaagactc
     7081 aagctagtag gctaagatgt tcaaagagga ctagcaatca caattggctt tttttgaaga
     7141 tagctttgag ataagtaagg tgactggtcc agagctgata gcaaaaaacc gaggaacagt
     7201 tcatatagct gtttctcggt tttttatgtt tccaagtctg tttacgattt ttcctgctta
     7261 aagtggtcta agccttcctc aatccaattg ggtaagctgg cttcaagagg cttaaagcca
     7321 atcttataac ggctgtttga aaagcgatga tgacttgaca catgatgctt ttcctcctcc
     7381 aaagttctca aggacaggct gaccttatga ctgtattcgt catagtcaat gacctgaact
     7441 aaaaccgcct caccaagtct taggatctga tgaatattat caataaatcc cgtcttaatt
     7501 tctgaaatat gaatgagacc tgttgtccca ttttcaaggg caacaaaggc tccatagggt
     7561 ttgattcctg taatggtccc atgcagctta tcgccaattt tcatcaatca aatacctcga
     7621 tggcctcaat gacaacgtcc tcttttggct tgtcttgtgc ccctgtttcg acagcagcaa
     7681 tgttatccaa gacctgataa gaggcttcat cagccaactg accaaatact gtatggcgac
     7741 gatccaggta aggagtcccc ccatgttcag cgtaggctgc tgcaatgtcc tttggccagc
     7801 caccacgctc taattccttt tgagaataag gaaggcttgt attttggacg ataaagaatt
     7861 ggctgccgtt tgtatttggt cctgcattag ccatcgaaag ggctccgcga aggttgtaca
     7921 attcctctga aaactcatcc tcaaagcttt gaccatagat ggattgccca cccattccag
     7981 tgccagtcgg atctccacct tgaatcataa aatctgcaat aatacgatgg aaaataacac
     8041 cattatagta gccttcctta gctagaccta agaagttagc aactgttttt ggagcatgct
     8101 ctggaaataa agccaatgtc agctcaccat gatttgtttt catcaccact cttggtcctt
     8161 catggccagc caaatctagc tgcggaaaat gtaattcttt gtcaatcaaa cctaattcct
     8221 ccaaggcata taaaatgccg ttttcttcaa ctgttttagt aataaaatct gctttttctt
     8281 gtaattgtgg gtgagaaacc cccatagcaa tgctgatgcc agcataatca aatagctcta
     8341 aatcattgag ctcatcacca aagaccagga tattttcagg ccttaagccc aaatgctcaa
     8401 caacctttga tacacctaga gccttagagg tgccctttag gaccacatca gaggagtgat
     8461 catgccacct tactaggcga agctgctcag ccaattcaac aggtaattgc aggtcatctc
     8521 ccttgtcctc aaaggtccac atttggtaga catcatggtg ctcattgtaa tccgggcata
     8581 cctctagtgt ggagtaaacc ttatcaatag catcactaat catctcgtta cgagctgata
     8641 agacagcctc gtgacgtcct gccatgccat aatcaatgcc gactgcattg gcccattttt
     8701 tataggctac aacagtgtct gctgggatag gtgcctgaaa gataatgttt ttttgattgt
     8761 ccttcacata agcaccattt agcttaacac aataatctgc ctgtaaatcc tgaacctcct
     8821 tgggcacacc atatctggcg cgacccgaag caattcctgt taggatccct tttttcttga
     8881 gctctttgaa aaccctctgg atagactctg gcatatagcc tgtgttcttt acgcgcaggg
     8941 tatcatctat gtcaaagaaa accatcttga ttttcttggc cttatacttt agttttgcgt
     9001 ccatactttc ctccatgcaa tagtactatt atagcattaa tgatcatctt gaggcactaa
     9061 atgatgtcgg aaagcgtata caacagcctg agtacgatca tcaacctgca atttggctaa
     9121 aatatttgac acgtgagtct taactgtctt caaggaaata aaaagctcat cagcaatggt
     9181 ctggttatca tagcccttgg ccaataaatg caaaatatcg tattcacgcg ctgtaagctc
     9241 ttcatgtaaa ttaggctgct gatcatgtgc cttaatcttc ttgtcaacct ccgtttcaat
     9301 ggcaagctcg cccttagcaa cctttctaat ggcatttaag atttcagctg cacttgatgt
     9361 ttttaacata tagcccttag ctcctgcatc aatgacaggg taaatttttt cattatcaag
     9421 ataggaggtt aacaccaaca cccttgcttc cttccatttg gagagtattt ctagggtcgc
     9481 ctctacacct cctaattcag gcattaccaa atccataacc acgacatctg gtctcaattc
     9541 aagggcaagc tcaactccct cacgaccatt agaagcctca cctatgacat caacatcttg
     9601 ctgcaaattt aagaagcttt ttaagcccat tcggaccatt tcatggtcat caactaatat
     9661 tacggttata ttactcatct tcatctccca tcacaagtgg cagtctaatg tccatcgaaa
     9721 cgccctttcc tttttgacta atcaaacgaa gcgttccagc caggtcattc acacgatctt
     9781 caatattttt aaggccatag cttaattccc taacctgacc catgtcaaaa ccaaccccat
     9841 tatcaaccat ttttagctgt agttctgttg gtgtttggtt caagtacacc tcaaggcggc
     9901 tcgccttagc atgcttgagg gtattgctga taaattcctg agcgatccta aagagattat
     9961 cctctatggc ctttggcaga gtgccaatat tttctttata gacaacctca atgccgcttt
    10021 tatcagttag ttccttgaga atcatcgtaa agccctctga caggctacga tttgccaatt
    10081 ctgtcgggcg caggtgcaat aataaaatgc gtaaatcatt ttgagcattt tgcagcatgg
    10141 cttcaacagt aactaattgt tgctgtagct gctccttatc catctgatct aggctcatag
    10201 aaacccctga caaaatcatc gacgaagcaa acaattcttg actaacagtg tcgtgcaggt
    10261 ctctagcgat tcgtttacgc tcctgttgaa caattttttg actatctaaa atataagcat
    10321 tctctttttt ctggatattg gttgttatat gagacatttt cgcagaaagt ctggtcaaat
    10381 tcgtgttgat ttcagaggtc tcctccaaat gaattctttg attgttgaga atcctgcgta
    10441 aatttttatt gatgctccgc ttgctattat catctaaaat aatccacaac aaaagcaaca
    10501 gcaaggttac agagatgata agcagcacaa ctgaaaacac caagcgctct agctgccata
    10561 aatggctccg caagtagtca aaggtgatcc ccagattatc catcacaaca aaaacaattg
    10621 ataaaatggt tatagtcgaa taaagccaga ccaaagcata ataccttttt ttcatcgtct
    10681 agccacctcg acatttcctg ctatagtgga tacgataatc ttaaccttct ttaaactgct
    10741 gtcctcggcc tctcctaggg tgatggattc atttcgtaaa tcgtactctt gaagctcaaa
    10801 aaaatcaaca ctagcataga tagagctgac ctctaaggta acagccacat caataggcac
    10861 taggatcttt gtgttgccaa agatctttct gataatgatg acattgtcca ttccagtcac
    10921 aatcacattt gtcagatcaa tcgtatcatt gccagaggca cgaataatat tgatatcctc
    10981 aaaggaataa taatcacttt catagttagc tgcgccaagc cattgatttt tgacctgtcg
    11041 cacagtcatt ttttcttctg caaaccgaat gagggcaaat cgattcttct tttttacctg
    11101 tgaaaaatga ttgataatca catacacaat ccccaacaga accgccataa taacataagg
    11161 gttcagcata aaaattaaga ataaaagcaa taagctaact gttagcaaaa agctattgcg
    11221 ggtatcttga ttataaaaac gcagagccaa taaaatcaag accaaaatta aaataaagct
    11281 tgataagtcg ttggccaaaa tggtcataat ccccatagcc agcagcatgc attcaacaag
    11341 cagaaagaat tgaaattttt tcattagact ccttccatta ccctgacatt ttatcaaaaa
    11401 ttaagcaaaa attcaccctt gagtggcatt ctagtaaaaa agaataccta gcttagcaac
    11461 tatgggcaag ccagatattc tatatcctat ttacgtttac ggtgttgtaa cagcgtcatt
    11521 ttgacctaat tcggtatgac tgcttgagtc tgttgtatct ccagctgatg gattaggagc
    11581 cgaggtatca gagctcgatg agctgcttga tgcacgtgtc tcctcagggt agaggtagag
    11641 gctaatatca cccttttcag aaaggctaat ctgggtacca taatacggtg tttgcccact
    11701 gacaaccgcc tttgagcttg gggagctcac ctgcacaaag cctgtcggag agctggagct
    11761 tggtacatag gccttgattc ttgcggcatc aattcctaaa gctgttagtg tattgactgc
    11821 atctgcatag ctgtactcag ttaccattgg catgatgact gtatcaccca ctgctacact
    11881 gagggtaatc ttggatttac cagctgggtt aaatttttct cctgcgcttg gagactggct
    11941 aataacggtg ttttcagggt attcatttgt cacgatacgc tcaatcttga tttttgactt
    12001 tggtacgcca taggtctcag tcagactggt catcacatct tgataatcct gtcccttata
    12061 attttccatc tcaaagcctt tatttccgat cgaaaggtaa aggtcaacgc tggagccttt
    12121 tcgcttagct gagccagctt gaggatttgt cttaaccacc tgatcctcac taactgtgtc
    12181 actttcaatc tgatggacct taccgacctt tagtcccgcc tcctccaaga cctgcttggc
    12241 agcattgaga ctagagcctg tcacatcagg aaccttaacc gtagttggct tggtcaagac
    12301 caaataagca aaaagagcca caccaacaac aaaaaaggaa aacaagattt ttaagagtgt
    12361 tcctagaaaa cgcccatttt ttttcttttt ttgaggcttt tgcagagtat ccatctggct
    12421 agtctgctca agtctagcat caactgccgc agatgcctga ctagcatttg ataccttagg
    12481 tgctgttaca ggagtcggtg ttacctttgg caagggcttt gtgctttcga catcatcaaa
    12541 gacaacctta cgctcacgac tgcggttata gctaagggct gtcatcaaat ccctgctcat
    12601 ctcaaaggtc gagcgataac ggtcacttag ctttttggca gtagcccgaa taacgacgtt
    12661 ttccaaggct tgaggcacat taggattttc atcaatgata gagggcagcg gcttttgaaa
    12721 atgctgcaaa gcaatcgtca cagcgctatc gccatcataa ggaatatgcc ctgttagcat
    12781 ttcaaagagc ataattccca tcgcgtaaat atcactttga atcgtcgctt tagaaccacg
    12841 cgcttgctca ggtgagaggt aatgcacact tcctagcata gaatttgtct gggttagact
    12901 ggtctctgca aaggcaacgg caatcccaaa atctgtaacc ttaacaacac ttgatttggt
    12961 caaaagaatg ttttgaggct ttaaatccct gtgaacaatt cctttttggt gggccagagt
    13021 catggcagaa agaacctctt ccatgattct caccacctca ttgttagata atggcgcatg
    13081 atcctgaatg tattttttca agtcagagcc atcaacatat tccattacta aaaattgctg
    13141 tccgtcttcc tcgcctatat cccgaatggc aacaatattg gggtgattta attcagccat
    13201 ggctcgcgct tctctttgaa aacgcgcaac agcaacctga tctgtttgat aattggtccg
    13261 caagacctta atggcaacgt cctcattatc cagaatcaaa tcgtttgcta aataaacatc
    13321 cgccatacca ccgcggccta tagattttag aatgcgataa cgaccagcaa atagcttgcc
    13381 aatctgaatc attctgcttc cccgctttcc ttatgcacca aagcaacggt gatgttgtct
    13441 aggcctcctc tttggtttgc caggtcaatc aaggcttgat ttttctcatc aaggctgatg
    13501 tcttgacata atatgtcaac aatctcctca ttagcaatca tattggttaa gccatcacta
    13561 ttaatcacta ggtaatcgcc cttttctaaa accttgacac ctaagtctgg ctctaccggt
    13621 gaagcttgac ctatagattg tgtgatgata tttttttgtg ggtggctagc agcctcctct
    13681 tcggtaatct gaccagcctt cactagggca ttaaccaagg aatgatcact ggttaaaaga
    13741 ctataatttc cctcatgaac caagccgata cgagaatcgc caatatgggc ataaatcgca
    13801 ttagaatcta ctagagcaac tgcctcaacg gttgttccca ttcccttata gtcttcagat
    13861 tgtcccaagt cgtagatacg ttggttctct gcttcgatgg ttgttaacaa ccaatccttg
    13921 atctgactaa gctcagtaaa atctgtctta acccactctc tacctaggtc tgtaacggtc
    13981 atctcactgg caatatttcc tgccctatga cctcccatac catctgctag gataacaagg
    14041 gtaatgcctt ttttattatc aaatttgttg ataaaatctt gattgtttga gcgcttttgc
    14101 ccaatatcgg tttttaatga aatcttcata taatcttttc tgactaggtc agtctcctcc
    14161 taaatactac aagactcgtc tgacttgccc aataaagaag ccatcagtct ggtattgctc
    14221 tggtgtaatc ataagacaac cgtccttgac aatatctgct tgtgcatgct tgagtgttac
    14281 ttgttcaaaa ttaggatgac gttgtaaaaa tttgtcaata acttggaaat tctcttcatc
    14341 aaaaatcgta caagtgctat aggttattat accacctttt cgcagcgttt gacaaacgct
    14401 agacaatatc tccagctgaa tttcctgcaa ttgctggaag tcctgccctt ccttgttgta
    14461 tttaatatct ggcttacgcc tgatgaggcc tataccagag cagggagcat caactaaaat
    14521 cttatcaaag ctgttcttcg caaaatgctt atgaacctct ctagcatcaa gcaccttagt
    14581 ttcaatccga tctgctaccc ctagacgctt agcattttca ttcactaagg ccagcttgtg
    14641 ctcatacaaa tcaagggcca ctactttgcc gctcgtcaaa taagaggcaa tgtgagctgt
    14701 tttccctccg ggtgcactac aagcatctaa aatcatttcc tgcccttgaa tatccagcgt
    14761 cggggcaact agctgactgg tctcatcttg gatcgtaatg tccccattga tgaaataact
    14821 gctggcagca aaattgccag ctctcttggt cagaccagtc ctagcaagta atgattgctc
    14881 tgatcctgtt gcctgcttga tctcatcaag ctttgtcaga tctgtgacac gtatgctggc
    14941 tctgcttctc acaaaaagac tttccatgat tgctacagct cgctcctcgc caaattggtc
    15001 gatcaatttt ttgactagcc agaccggtac tgagtaagca acagcatagt atttgttttt
    15061 tcgcttgatg ctcttgatat ctggtaaggg cttattggtc agctggcgca aaacggcatt
    15121 gaccagctta tctgctcctc tgccatgagc tctcgccttg gcaagattaa cagcgtcatt
    15181 aacaatagca tgagcaggca ccttgtctag gtaagccagc tggtaaaggc taagcatcaa
    15241 gagataataa acccatttat ccagcctgtc tcggtcctca atatagtgag ccagatacca
    15301 ttctagggtt atcttcctag agatagtccc gtaaacaatc tctgtgacta gagccttgtc
    15361 cttatcactt aaaaactgat tcgccagctg gtgcttcaag gcaaggttag aataggctcc
    15421 atgatcaaaa atatcctcaa cgataagcag cgcctgtcct ctagctgatt ttttccaatc
    15481 attcgccaag gacatcaccc acctctaggc ttctgccaat accatttaaa aagtcaacaa
    15541 taggcatctt tggcttgcct gctggttgaa cgagcgtcaa ggatagagcc ccctcacctg
    15601 ctgctacgac caatgctttt ttagttttag cgatgatttg cccagcagat ccagagcctt
    15661 cagccaattc agcctcataa attttgaagc gctgcccatc taataaggta tgagccaccg
    15721 gccaagggtt cattcctctg atatgattaa acacctctct tgctggcttt gaccagtcca
    15781 gtctttcttc ttctgctgaa agattgggag aaaaggtggc ttggctatgg tcttgaggaa
    15841 ctggctttag gtcaccagac aagtaatcag gcaaggtttt caataataaa tctcgtccta
    15901 gaatggccag cttatcaaac atggtaccaa cattatcagt atctaaaatt ggaaggcttg
    15961 cgcttgatat catatcccca gcgtccatct ccttaaccat ctccataatg gtaactccag
    16021 cttccttgtc accattgata atagcataat ggatcggagc gccaccacga tatttaggaa
    16081 gtaaggacgc gtgcacatta acagcaaatg tcaccgaatc caataagact gttggtaaaa
    16141 attgcccaaa ggctgccgtt acaatcccgt ctgctcctaa tgccatgata tctgctagct
    16201 cctgtgaacc agatagcttc tcaggctgaa aaacaggcag ctgatgtgca agcgccagct
    16261 ttttaacagg cgtcattgtg atgtcttttt tgcgaccaac cgcacgatca ggctgggtca
    16321 cgaccgctaa aatgtcatag gctggttttt ctagtaagcc ctgcaaaaca gttgctgaaa
    16381 attggggagt gcccataaaa attaatcttg tcatctatgt cctctatttt ctttcttttt
    16441 cattatagca tagcttggcg caaagtccgg taaagaacac ttacataaag ctctgtggct
    16501 cctgatcaat gataaccttt agctcgcgat tatcctgctc ttggctccaa tcaagaattt
    16561 gattcagggt agcttcaagc tgatcctcaa agcgatactt caaaataatc tgataatggt
    16621 aaagattgtg cgttcttgca attggctttg gcgttggccc taatattctg atctgatcag
    16681 acaagccctg cttcaatatg gtcagcagtt gataggcctt tttgaccacc tcttgctcac
    16741 tcttatgcga tagggtcaga cctactgtga aataataggg aggatagcct agctttcgtc
    16801 gaatccccat ttcataagcg taaaaggctt caaaatcctg ctttttggcc agttgaatcg
    16861 cgtaatgctc aggattgtag gtctgaatca ggacttcacc tggcttgtct gcacgtcctg
    16921 cacgtcctgc aacctgagtc agcaattgaa aggttcgctc cgatgcccta aaatcaggta
    16981 aatgcaagga agtatctgca tttaaaacac ctactagggt gacgttggga aaatccaacc
    17041 cctttgcaat catttgtgtc ccaagcagca catcagcatc accatttcca aactggctta
    17101 aaatagcctc atggcttcct tttttacgtg tcgtgtctac gtccattcgt aatattctag
    17161 cttccggcaa cacttgcttg agctcatcat aggctttttg cgtccctgtt ccataatagc
    17221 gtatgctttt gccttgacag ctagggcata gcttcggaat agccctttga aagccgcaat
    17281 agtgacaatt catggttttc gtatccatgt ggagggttaa ggaaatatca caatttggac
    17341 attgatcaac atagccacaa tctcgacaca tgataaagct agagtagcca cgcctgttga
    17401 gcatcaaaac agcctgctct tttctagcaa gacgctcttt gagtttatca atcaaataag
    17461 gggtgaagct gctaacctcc tgctgaccaa tataatctcg aaaatcaaca atctcaacct
    17521 gaggcatact ggcaagagga ttggctctct cagtcagctg gataaactga tacagtccct
    17581 tgctggctct agcgcgacta tcaatactag gggtcgctga gcccatcact aaggcagcct
    17641 tatggtgcct tgcacgaatg agagctacat ctctggcatg gtatctggga ttagattcct
    17701 gcttgtaggt ggcctcatgc tcctcatcaa taataatggc tccaatattt tctaaaggtg
    17761 aaaaaatagc agagcgagca ccgaccacca ctctagcctg ccctgtctta attttctgcc
    17821 attcgtcaaa tttttctcca tctgacaaac ctgaatgcat aatagcgacc tgtcttccaa
    17881 agcgggaaat aaatcgagag gtcatttgag gcgtgaggga gatttctggc actaagacaa
    17941 tagctgtctt tccttgctca agcacatgcg caatcacatg aagatagacc tctgtcttgc
    18001 cagagcctgt aataccttcc agtaaaaagg gcttagcctc tctgccaaca gccttcgtaa
    18061 tctggtcaac agcttgctgc tgctgctgat taagctttaa gagtggggct gccttgatgt
    18121 gattgaaata atcctcactg cgattgacac gtcgctcctc aagctcgatc agctggttgg
    18181 tcacaaaata gctaacaacc tctctagaat aatcctgata aagcttggct agcttatctt
    18241 tttgtggatt ggctaacaaa taagccttta aggcttggcg ctttttagcc cgatttgaaa
    18301 tcttatgctc ctgtaaggct aatctattga cctgatagta agtctcggtt ttgattgtct
    18361 ttttgtcctt ggctagataa gttgccctaa tcttaccaga ctgtatcagc ctaaggacac
    18421 gtccctcctg ctctggactt agcttagaat aaagcaagga atccccatta gagaaaacat
    18481 cagcaaggtc agccgcagct aagtcagctg tcggggtgag cagccgatcg taatgagaat
    18541 taagtaggct aggaagcatt gcctttaaga gggtgatttt gtaggaaaag actgtttgtc
    18601 gtaattgctc tgctaatgcc acctgctcct gatttaaaac aggctcagca tctaaaactg
    18661 accaaatagc cttcaattgc tgcgttgatt gactagaaaa gccaataaca aagccctgta
    18721 gcaacctatt gccattacca aaaggcacat gaacgcgaga accaatctta accagagata
    18781 atagctcatc tggaataaga taagaaaagg gcttatcggt ttgcatcaag ggaatatcaa
    18841 caatgacctg tgctatgtgt tgcattttga cttcctttct atcaagaaat ggacctgcaa
    18901 tatgaaaaaa actaagattg actcaacctt agattttttc tccctcttct tctttttctt
    18961 ttgcaatctg ctcttttatt ttacgctctt cttcttctct tgctaaacgc tctgcctcaa
    19021 tccttgcacg aacagccgca cgcttagcag caggatccgg gtgaatcaca acattgcctg
    19081 actcaatctc ctctagtgcc tgaagtgttg atttgacaga cttaaaggac tgtgtcggtg
    19141 cagcacctgc ttctaattca tgagcacgct tggcctgtaa aataacaagt gaatattttg
    19201 atgggacttt atctaataaa gtatcaattg aaggttttaa catcatgggc tttactcttt
    19261 tctatttcta tcatctgaga gattttgttg ttttaatcat ttgatcatag cgaccaatca
    19321 cacgctcaac gcgaaaatgc tcggtctcaa taatacgctt gacacgctct gcagctaaag
    19381 gaacctcgtc gttgaccaca gcataatcat actctcgcat gagcgcaatc tcttccttag
    19441 ctctttcgat acgcttggca atcacctctt ggctgtctgt tccacgacca accaaacggt
    19501 cctgcaattc atctaagtct ggcggcgtta gaaaaatgaa gacaccatca ggcaccttag
    19561 ccttgacctg caaagcaccc tgtacctcaa tttccaaaaa gacatcaatg cccttatcaa
    19621 gggtttcgtt aacataggtt aagggagtgc catagtaatt gccgacatac tctgcatatt
    19681 ctagcatttg accatttttt attagctctt caaattcttc tcgtgtgcgg aagaaataat
    19741 caaccccatc aacttcacct ggtctctgtg gacgtgtcgt catcgaaaca gaatattcaa
    19801 atttatgatc tggcgttgaa aaaatctctt gtctcaccgt tccctttccg acacctgagg
    19861 ggccagagaa aacgattaac aaaccgcgtt cagacattgt gttctcctta ttgattgctt
    19921 tctaatagtt tatcaaaaag gctatcgttt ttcaagacaa ttatcagccc aatcctaaga
    19981 aagaaaagga agagatagac gccttctcaa agctagaggc taaactctgg cttttgaaaa
    20041 gcatacactc tttccttttt atttcgcata atctattgct cgcaactcac gaataacagt
    20101 taccttgata tttcctgggt aatccaagtt attttcaatc ttttctctta ccttgtgtga
    20161 gagaaccaca atctcgtcat cagaaatctt ttctggctga accatgatgc gaatctcacg
    20221 accggcttgg agggcaaagc tactttgaac accatcaaag cttgttgcga tttcttcaag
    20281 gtcacgaaga cgcttgatat agttttccac agattcattg cgggcacctg gacgagcaga
    20341 gctaagggca tcagcagcag ctaccagaac tgcaataacc gaatccggct cgacatcgcc
    20401 atgatggctg gctatggtgt tcacaacaac agggtgctcc ttgtacttgc gagcaaactc
    20461 cataccaatc tcaacgtggc ttccttcaac ctcacgatca atagccttgc ccatatcatg
    20521 caagaaacct gcgcgacgtg caagtgccac attttcacca agctcgccag ctaaaatacc
    20581 agctagctta ccaacctcga ctgagtggcg taaaacattt tgaccaaatg aggtacgaaa
    20641 ctgtaagcgc cccatgatct taatcaaatc cgggtggagg ttaggtgcac cgatctcata
    20701 ggcagcagcc tcaccatact cacgaatcct attgtccatc tcaagacgat ttttctcaac
    20761 caattcctcg atacgcgccg ggtgaatacg accatcagca atcaaggact ctagggtcat
    20821 acgagcaatc tctcgacgaa tagggtcaaa gcctgataaa acaaccactt ccggggtatc
    20881 gtcaatgatc acatcaatcc ctgtcagact ctctagagta cggatattgc gaccctctcg
    20941 accgataata cgccctttca tgttatcatc aggcaagtgc acacttgtaa tcgtctgctc
    21001 agtcacatac tcaccagcca tacgttgcat ggcctgtgct aacaggtcct tagcagtctt
    21061 gtctgtcctg tccttgatgt cacgctctgc atcacgaatg cgtgttgcga tctcatgcgt
    21121 cagcttgttt tcagtttcca tcaggataac ctcacgcgct tctgcaatgg tcatagcagc
    21181 aactcgttgg agctctgctc ttttgtcttc ctcaagtttt tcaacctgtg cctgtcgctc
    21241 atcaatgtgc ttagatttat cggtcagact ttgctctttg ctatctagta ctttttcttt
    21301 acttgataga ttttcatcct tacgatcaag agttagagca cgctctgcca agcgcgtctc
    21361 cagctgttta agctcttgtc tttcagattt aaattcctgt tcaatttctt cacgatactt
    21421 tcttgcctct tcctttgctt ctaaaagtaa ttctttacga cttgctttac tttcacgttg
    21481 tgctgtcttt ttgatatgag cggcatcggc ctttgccttg ccacgaatat caacagcatc
    21541 ctgttcagcg tttaaaagag tcaactctgc agcttccttc gcagacttga gtctaatcga
    21601 aataagtgca taacctaata ttacaccaat gaggccacag acaagtaacg ttatgatatt
    21661 aattaacatg tctttacctc aataatagtt tagttttcat taacagaaag ccatctctta
    21721 gtctatcata aaatgaagat ttagacaatt taaaatccac ctacattttt ctaaaatcta
    21781 gtgattttat gttatgatat tgataaaaat aaaaaggagt ttcttatgcc aaaagaagtt
    21841 attgttgaaa gctttgagct tgatcatact attgttaagg caccctatgt acggctaatc
    21901 tccgaggaat ttgggcccca gggagatgtg attacaaatt ttgatgttcg acttgttcag
    21961 cctaatcagg ctgccattga gactgccggt ttacatacca ttgagcattt attagccaag
    22021 ctcattcgtc aacgcattga tggaatgatt gattgctccc cctttggctg ccgcacaggc
    22081 tttcacctca tcatgtgggg caagcatagc tcaacagata ttgctaagat catcacgtcc
    22141 agcctagagg aaattgctac aagcatcact tgggaggacg ttcctggcac aaccattgaa
    22201 tcctgcggca attataagga tcacagcctt tttgctgcta aggaatgggc acagcttatt
    22261 ctcaagcaag ggatctctga tgatccattt aaccgccatg tcacctcata aaacgaaagc
    22321 ctctcttttc tgctaatgtg aaggaggctt ttaatgtatt caaaaaggtg ccaaaggcaa
    22381 ggctcaatgc ccttaccttt agcacctgtg ataactagag tatccagttc aggatcacac
    22441 cttgtcttct aagcattaat agtctaagtc ctctgcatgc cccttgccat ttccgacaaa
    22501 atagcctgtt ttgcaattca atgaaaagag gtaggtgcca tcaggcttaa acatgttgta
    22561 atagccattc ccattgataa tattgaccgg ctctaggata taatcattgc ctgaaatata
    22621 gccccttgct tgtgaggtag ccacaatacg ctcaagcaca cctggattaa aggcccaagc
    22681 agggtttcct gtatcagcaa tcatagcctg attgtagggc acacgagaca ggtcacgctg
    22741 caatattgaa gggtcatagc ctgtaatgcc atacattgga gccactggag ctggtacagc
    22801 aggaacctgc ggagctgcag ggcttgctgg taaggcagaa gcagctggag tgctagctgc
    22861 ttgggtagca gacctgcttg ctagctgctc acgacctgcc ttgatgcttg attgtagcaa
    22921 tgaatcaagt tttgcattac cagtggttag cgtatcacta gctaggtcat caaaattagc
    22981 atcagctttg acctcagctg caatcttttc accattgaca attgcagctg ttgtaaattt
    23041 cccattaacc gcctgaatag ctgttacttg ctttttcagc ccagtaacct tttccttagc
    23101 cttgtcataa taggctgtcc cttcaagcct ttttaaagca gtctccaaat tcggtaactg
    23161 atcaaaggcg ctatttttta gggttgtttt atcattatct gtgaaaaatg tcttgtaaag
    23221 atcttcaaaa gccttagcat tagcctttgt tttgttggtc tgattagctg ttgatgcttt
    23281 gctccttgct tttttagaaa cagtagcctt tgactgaggc ttatgcttag acagctgata
    23341 gatatggttg agggcaaagg ctgaggctac aagggttagc gtggctaaca aaatagcaaa
    23401 cagaggcttt ttctttttag acctacgact agcatagcta tctgataaaa tactctctac
    23461 ttctgcaggt cgctcgctaa ctgcgtcatc agctagctgc ccagtaaaat cactagcaga
    23521 atcagtagct gccgctgaag tgtcagctct agctgctaga ggctcaatga atgaggtctc
    23581 accggctggc ttctcctctg ttgaagcctc gtccactggc tcaacatcaa ctaagccggc
    23641 tttgctgagc tcctctcttt gttttttgat aaagttatcc agacttgctg tatctaactc
    23701 catatacttt gcatcaaact tttgtgatga cacttcgtta cgatgccgct taatatattt
    23761 gtctaaaaca ctatcatcct cggtaatccc tgcttttagc tctgagtcct tgcgtactgc
    23821 ctcaccgatt gtcatttttt tggcttcatg aagctccaaa ttttggcttt ctgcctctga
    23881 ttcaaatgct ttgctttttt ctgacacgtt ttttacctct ctatatcaga ttgcgcttta
    23941 ccctctctcc ataaaattga tacaaatcaa cccttagagt accattataa agcttacgtt
    24001 ttttatcagc tttttgacca tatttttgtt caaaatgatc atcactcgtc aaaataaact
    24061 tgctccaggt aactaatgga gcaaagacct gtaccatctc attatacaag atgtctactg
    24121 ctttgtcatc aagcaaacgc tctccataag gaggatttga aatgatgaca ccgtttatct
    24181 tgtctgtacg gaaatcctgc aagcgcattt gcttaaaggt aatgatatca gccaagccag
    24241 cctcctcagc atttctcttg gcaagctcaa ccatacgacc gtcaatatca aagcctgaaa
    24301 tatccagctc aatatcataa ttagcctctt tttcagcagc gtcacgaacc ttttgaacac
    24361 gatctttgtc cacccagctc cattcctcaa aggcaaagga gcgattaaag ccaggagcga
    24421 tattcattcc gatgagagcc gcctcgatac aaaaggtccc cgatccacag gtgggatcaa
    24481 ccaagggctt atccggaaac caattagaca gcttgaggat agctgctgcc atgttttcct
    24541 taataggagc tccccctttt tccacccggt agccacgctt aaataggctt gagccactag
    24601 tatcaatcat cagggtagcc tgatccttta agattgagac ctcaattttg aactcagccc
    24661 ccacctcttg aaggggaata tgctccggtc tatgaaaatg ctgctgcaat tttctgacaa
    24721 tggctttttt ggtaatggct tgaacacttg gctcgttgtg cagggttgac ctgacacact
    24781 tagcctttgc aataggaaac ctagcaccta agggcaaata atgctcccaa tccaaggcaa
    24841 atacgccctg aaacagctcc tcaaagcttc gtgctgggaa ctgacctaca ataatcttaa
    24901 tacggtcagc cgctcgcagc caaagatttg ctttagcaat agcttcaata tcgccttcaa
    24961 agaagacctt gccattatct actcggcagt caaatcccaa ggcccttaat tccttaccca
    25021 caacagcctc taggccagct gctgcagttg ctactaatgt aaattgttct ttcatatgac
    25081 tctttctatc ctaaccaaat aaaagctagc atatgctagc ttaacctatt atgcaatttt
    25141 ctataagcca tgttttgttc cagaaataac taggtattat ctccttcgat aatcatctgt
    25201 ctactgtttg tcaacagtca ggatagcttg ttcgtttcca actatcccat gcccctacca
    25261 aagtttgggt tgctagcttg aggggtttac cgcgttccac tttttacgtt tccataaaaa
    25321 cttcgtcact gtggcacttt cagagctact ctggcatatc aaggacttag ccttttcact
    25381 cgccgtaatg tgtcaaacac atccctaggc ttatttgttc gcctagcaca aacactacca
    25441 gcatcacagc cggtgctagc atggactttc ctcatagtat tgcaatacta cgcgattatc
    25501 caaaaattgc acatctacat tactcaataa tttgctttcc aaaaacctct ttttccagct
    25561 tgctaatgcg ctttagcatg tcaaaattgg tggctgactg tgctactctg gttggctgtg
    25621 ataccgcctg agagctgcct gctaaaggat cacgcacctg agccttagcc ttttttaagg
    25681 cttcattttc agcctttagg gcctcgatct gagcattgaa atactcataa tccttgatga
    25741 cgttatcaag gaattcgtcg acctccttct tatcaaagcc acgcatactg gtcttaaatt
    25801 cttgctcaaa aatgtccttt ggactataaa ttatacctgt cattctatac tctccaaacg
    25861 gtcaatcttt ttcaaatatc aaactttgat atcactactt atgatacaga aaaataaatt
    25921 aaaaagcaag tatttaaata ccagtgattt ttaaatatca ctagctactc atctgcaatg
    25981 tcatttaaac gctcaaagtt taggaaagaa agggggtaac agggctgctc cttcatagct
    26041 gctaccaaat agcttaggcg cgtttcgtgc tcactatcat aaaaaagata ggctccgtct
    26101 gtattgtgaa tcaaaaagtg atggtagctc tttagctgtt tagggctttc atagctggga
    26161 tagctatatt tgacaaaatc agtctcccga aattgctgca gctgctgctg attgcgatca
    26221 ttccaagtgc tgccatgcgt ttcaaaggca aaaatagtcg ctgtctttaa ggggtaggtc
    26281 tttttgaggt cattagctac ctctaaagcc cactgctcaa accctaaatt cccagtaaaa
    26341 ataaaccagt ctaccccctc ctcaagataa gcaatcagat ctctttctat cgcttttttg
    26401 ataatggcaa ctcttttatc cttttcacta aagatgccca gctcaaaact tcgatagcct
    26461 gttacgagaa ttgcagtcat tagatgttat cctttcaaaa atatgttata atgtgaatgc
    26521 ttaaattatt attaagtcat gatgttagga gaacaatggt taactaccct cataatccta
    26581 ttcgccaaaa ggtgacccct cttcaaaagc agcaaaagca caagcaagta gactttgcta
    26641 atcgtggtat gtcctttgaa gcatccatta atgcaaccaa cgcttattac ttggccaagg
    26701 gcattgctgt cattcataaa aagccaactc cgatacagat tgtcaaggta gactatccaa
    26761 gacgtagtcg agccaagatt gttgaggctt attttaagca ggcttcaacg accgactatt
    26821 ctggtatcta caaagggcat tatattgatt ttgaagctaa ggaaacaaga caaaaaacag
    26881 ctatgccaat gaaaaacttt cacgcgcatc agattgagca catggctgct gttttaaagc
    26941 aaaaaggcat ttgctttgtc ctccttcact ttgcgacact aaaggaaacc tattatctac
    27001 ctgccaaagc actcattgat ttttatcaga ttgatagggg caacaaatca atgccacttg
    27061 attatatcag aaaaaacggc tttgaggtca agctgggagc atttccacag gttccttatt
    27121 tagatattat agaacaaaaa tttttaggcg gtgattacaa ttaacaatcc aaaaatcctt
    27181 aaattcctga agtatacatt aggtgctatc cttagcctta tcattgtgac aattacctta
    27241 ggtggccttt tgtttgctta ctatatcagc agtgccccta agctttctga ggcccagctc
    27301 aaatcgacca attccagtct tgtttatgac ggtaataatc atttgattgc tgacttgggc
    27361 tctgaaaagc gtgaaaatgt tacagctgac agcattccta ttaatctggt caatgctatt
    27421 atttctatag aagacaaacg cttttttaat catcgggggg ttgatctcta tcgtatctta
    27481 ggtgcagcct ttcacaattt aacaagcaaa acaacccaag gggggtctac acttgatcag
    27541 cagctgatta agctagccta cttctcgaca aacgagtctg accagacctt gaagcgaaaa
    27601 gctcaggagg tttggctggc ccttcaaatg gagcgaaaat ataccaagca agaaatcctg
    27661 accttctaca tcaacaaggt ttatatggga aatggtaatt atggtatgct gacagcagcc
    27721 aaggcttatt atggcaagga tttgaaagat ttgtcctatg ctcagctagc cttgctggca
    27781 gggattccac aggccccaag ccagtatgac ccctacacac agcctgagac agctcaaagc
    27841 cgccgaaata ttgtccttca gcaaatgtat gctgaaaaga acattaccaa ggctgagtac
    27901 gaagcagcta tcgccacacc tatatcagaa ggcctacagc ctctccagca acgcgccagc
    27961 tatccaaaat atatggataa ttacttaaaa caggtgatcg agcaggtaaa ggctgagacc
    28021 aacaaggata tctttacctc tggtctaaag gtttacacaa acatcattcc agaggctcaa
    28081 aaaaaacttt atgacattta caattctgag gactatgtgt attaccctga tgctgacttt
    28141 caggttgcct caaccgttat tgatgtcaca aatggacacg ttatcgccca attaggagga
    28201 cgcaatcagg ataccaacgt ttcctttgga accaatcagg ctgtcttaac cgatcgtgac
    28261 tggggatcca ccatgaagcc gatcacagac tatggacctg ccattgagtc cggtgcttac
    28321 aattctacag ctcaaacaac taacgactct gtctactatt ggccggggac acacactcag
    28381 ctctataact gggaccggag atactatggt tggatgacca ttcaagctgc tctcatgcaa
    28441 tcacgaaacg tccctgcagt tagggctcta gaggcggcag gtcttagcta tgcacagtcc
    28501 ttcctcagtg atctaggcat taattatcca gagatgcatt attcaaacgc catctcaagt
    28561 aacaatagca gttctgattc aaaatacggt gcaagcagtg aaaaaatggc tgctgcctat
    28621 gcagcttttg ccaacggtgg actctattac aagccacaat acgtcaataa aattgaattc
    28681 agcgatggga ccagcaaggt catcgaaaat aagggcaagc gtgccatgaa agaaacaaca
    28741 gcctatatga tgactgatat gctaaaaacg gtactaacct acggtacagg tactgctgct
    28801 gctatcccag gagttgcaca ggctggtaaa actggtacct caaactatac cgatgaggag
    28861 ctggcacaaa ttgttgagac acatggacta tctcctgatt acgtgggaac aatggcgcca
    28921 gatgaaaact ttgtcggcta caccaaccga tacgctatgg cggtttggac tggttataaa
    28981 aaccgtatga cgccaattta tggctacagc ctagaaattg cttctcatgt ttatcgcaac
    29041 atgatcagct atctcaccgg cggctacagc gacgattgga ccatgccaag tgggctctat
    29101 cgtagcggcg gcttcctcta cctaagtggt acctatacaa acagtagcga ttatacaagc
    29161 tctgtctaca acaacctcta tggtaataac agctcagctt caagccaatc ctcagatgag
    29221 gatacaactg aagacagcca ctcagaagca aacgacagca caacgtcatc atcagagcag
    29281 caatcaagct ccaccgatga taagaaaacc aactgataac aaaaaactgg ttcaaatgtt
    29341 ctgaaccagt tttttcaatt atttggctaa ggcacccatc ggatcccaag gggcaagtac
    29401 ctgtggttct gcctcatagg ctgctaattc atcagctgtt agtaggtcct tgcgaacaac
    29461 aatctggtaa gtatactcgt ccatccaagc atcagaagca acaaagtatc ctttgtcacc
    29521 aaccttgtct ccccaagaat tttcaacctt ccatttgata ggcttaccag tatcatctaa
    29581 atcaacacct gtcaaaacca tagcatgtgt cattaagctt tcgctgtaat caaggcgacc
    29641 agccttgtct tggctcaact gaatatccat acctgcctga aaatcatagg tattaagggc
    29701 tagaatcccc ttttgacgat ctgatacctg accaacgtct gaaccaaacc aaacggactc
    29761 tccagcctgc atttgcttaa tagcaagctc cttgaagcgc tccatatcaa gattaaggta
    29821 gcgcacctca ggactgccaa caacattacc aagcatatca accgtataag atttgccata
    29881 aggcttatca gctgttgggg cgttgataac agacacataa tcagacagct ttagaccaac
    29941 atatttttca taaaatgcct gtggtgtgat gcccttatca gcatgatagt gattatcctt
    30001 atcacgataa gcaaaatcaa attgacgagg tggcaaacca agattcatgg ctaagaaatt
    30061 aaagatttcc tgaagtagct cttctttttt agcctgtact gcctgatgat cagcaccagc
    30121 actgatcaca tctcgaagaa tctgagcgtc ctgacgcaag agcttattga ggtattgatt
    30181 tagctcacga ctattgcttg atgacacaga ctctgggtag actgattttg gcacaacacc
    30241 gtatttttca aacagggcta caaccatgtc ccactgacca ccgtcttgct gcggaacgtc
    30301 caaaagaaac ttaaccctac ggctagtcaa ggcttgatca gcagttgcaa tcacctgttc
    30361 cataaaccag tttgattttt cgtatttgtc ccagaaaaag gtgtgtgctt gtgacaactc
    30421 aaaatcttct aatttaaatt ctgaaataag cttatggcga aaggtgttta aggctgcaaa
    30481 catccagcaa cgacctgaag ccttttgatt agagacctta tcctttgtca agtcaatgga
    30541 aaagacaaaa tcattgtcga tctcactttg tcttgtctcc aaggatttaa gcaagccatt
    30601 gtgagtgatg gcattttcaa gagctaaata tttagcatta gcttcataat tagcatatag
    30661 ctgttctgta aatgtctctg ttaatactga catcattttc ctccaaagat aataaataac
    30721 aacacctaaa aataaagttg acagaaaaat ccataaatac tgtcaatttc attttcaagg
    30781 attacttcta ttatagacct tatttgatat tcttcaagta aaaaaattag gctaacttaa
    30841 ttttttaaag ctaagcagca gctttccaat aaccagacaa aaagccatct caaaagacga
    30901 caaaacctgc tggactttga gcacctaaac atgtcatatg tccacctcag catgaactca
    30961 aagaagctag ctgtgtctgg ctatgacttc agtttaatca ttagcttgcc ttagccacaa
    31021 aaagaatcgt ctccactgta gcaaaagtgc ttgatataac accatcggct aagtcaaggg
    31081 gcccctgata gttaactgaa acatatggca aagctaaaac caaagacttc ttctccttaa
    31141 agcctctggt ttttagttag ctgagcattc tcctttatct tggctgcttt aagataggga
    31201 caaatcaaca actaccccaa tcccatttac aaaaaagccc taagtcagag ccttcatagg
    31261 gctaagggtg agggaagctc ttaggcaaca gctactggat ttatgcctaa tagaagctcc
    31321 tgtccctcct cacctattta aaatagcatt ggtttatcta tagcctgtgt aggtttgagg
    31381 atcacttcca aaagtcatca aaaatagtaa ttggcagatg gcgcttgtgc tgccctttat
    31441 gccaccagtc ttcaatcctt gcctgagctt cagcggaaat cgtatgcccc tctaagtaat
    31501 catctatctc ttgataagta acacctaatg ctacctcatc tgcaagtcct ggcttcttat
    31561 cctctagatc tgctgttggc accttctcat agaggctggg gtcagccttt agcaccttta
    31621 acaaggcctt accctgccgc ttagtcaagc gaaaaagggg tagaatatcc gctccgccat
    31681 caccaaactt agtgaaaaag cccgtaacat tttcggcggc atgatctgtc ccaatgacag
    31741 caccagctgt ttgaccagcg atagcatact gactaatcat acgctgacgt gccttaatgt
    31801 ttcccttatt aaagtcagaa atctcaagcc ctgccgcctc taaggctctt agctgaccat
    31861 caacagcctc tttaatatta accgtcaagg cttgatcagg ttgaataaat gctaaggctt
    31921 tttgtgcatc tgcctcatct gcctgaacac catagggcaa gcggacagcg ataaattggt
    31981 actgctcatc acctgtttca gcgcgcagct cttcaatcgc catctgagct agctttccgg
    32041 ctaagctgga atcctgacca ccagaaatcc ctaagacata agtctttaaa aaagggtgct
    32101 ttaacaaata agcctttaaa aaatcaaccg actggcgaat ctcctgctta ggatcaatta
    32161 ctgctttgac ctcaagctga cgaatgatat cctcttgtaa tgtcatatca aatcactcct
    32221 tttacaggct tccttgcgga ttttgtcaat aagatgcatc ttattttgcc aaacatcaag
    32281 cgcaagatcc acagggtaat gctgcggatt caagacacgc ttatattcgt cccaaagctt
    32341 atcaaattcc tttctagcat aagccttgat gtcttttaag cttggcagct gataaacgag
    32401 ctttccttta tcaaaaatat ctactagcaa aggaacagca tcaaaatctc tgacggtttt
    32461 attaatgtag gtataagtcg ggtggaacat gtgaatttcc tctaggtcat tgacattaac
    32521 acctgtaaag gtgatgtaat cgccttctga cttgcccttt tcgcggctgg taattcgcca
    32581 aacctgcttt ttacctggtg ttgatacctt ttctgcatta tttgatagct tgatagtatc
    32641 gcgcatggta ccatctgcct gctctatcga aacaatctta taaaccgctc ccagagctgg
    32701 ttgatcatag gctgtaatca attttgttcc aacaccccaa acgtcaattt tagctttttg
    32761 cattttcagg ttgagaattg tattttcatc taaatcattg gaagcgtaaa tcttagcctc
    32821 tgtgaagccg gcagcatcca gctgctggcg taccctttta gataggtaag caaggtcacc
    32881 agaatccaga cgaacaccca agaaattaat cttatcacct aattccttgg ccacacgaat
    32941 agctgttggg acacctaccc tcaaggtatc ataggtatca accaagaaaa tacaatcctt
    33001 gtgcacactg gcataggcct tgaaagcatc ataatcatta ccataggcct gtaccagagc
    33061 atgtgcatgc gtgccagaca caggaatgtc aaaacgcttt ccggcacgaa cgttactagt
    33121 tgcgtctgct ccgccaataa tggcagcacg tgtcccccaa acagcagcgt ccatctcctg
    33181 agcgcggcgt gtcccaaact ctaaaagtgg ctcatcttca ataacagagc gaatacgagc
    33241 tgcctttgta gcaatcaagg tttggaaatt cacgatattc aaaagagctg tttctactag
    33301 ctgacattga cctaaaggtc cctcaacctg aacaataggc tcattggcaa agaccaagtc
    33361 tccctcttgt gctgagcgaa tcgttagctc taaacgaagc tctctgagat aggtcaaaaa
    33421 agcagggctg tagcctagct ccttcaaata agccaaatcg gtctcagaaa aggtcaattg
    33481 ctcaaggtat tctacgattc gttgtagacc agcaaaaact gcatagccat tgttaaaagg
    33541 ctctctacga aaataaacct caaagacagc attacgatta tgaatgccct gctcaaaata
    33601 aacctgcatc atatttaatt gatataaatc agtatgaagg gttaagctat catctctgta
    33661 catataagta actccttaac ataattgtta ttattatacc atatttttgg catagacctg
    33721 taagattcaa ctaaaatcct ctgctcaagc tttctaaaaa agaagccttg agctgctatt
    33781 aagcctgaca tattttttgc cagtaccttc ctaaaaagtc tatagcacaa gggcttatgg
    33841 ctttttaaca aaagcagttt cagttgatag cattcataaa aaaagattga agaaattgac
    33901 caaaatagcc cctttcttca atctatttaa ctcacacctt agccttttaa cgctttttta
    33961 cacttgagct gactgtagca gccaaagact agaatccaaa tgctagcacc aattgccccg
    34021 atataggtgg acttctgtaa aaacagtgaa ataaaaacaa aggcaaaaaa ggctagggtc
    34081 aatggtgttg ttagctgata acttggcatc aaataaccat ctggcataaa gtcactggac
    34141 tgacgatatt tccaatgcgc aagcatggtc aaagcataaa tcgcaatata aacaccagat
    34201 gatgaggccg taatcagcga aaaggcatct gcaacaccgg gcaggatatt aatcaaggcc
    34261 gacaccccaa cagcaacagc agaagcaata atagccctac ttggtacccc ttgacgagat
    34321 agggtgttaa tcctcaaggc tttagtaaga gcatttgggg tctcattagc gatttgatac
    34381 aaatgccgac ctgtcgaata cagggtcgaa tttagggctg atgctgctga tgttaagacc
    34441 acaaaattaa ttaaagcagc agcccattta atcccaatca gcttaaagac catcacaaag
    34501 ggagactcgt ccgtaggcaa ctgataccaa ggcacaatcg ccataataga caccaaagca
    34561 ccaacgtaaa aaatgacaat ccgcatcgga atctcttgga tggccttggg caagaccttt
    34621 ctaggatttg cggtctctga ggttgtaata ccaacaaatt cgatggcctg ataggcaaag
    34681 aaaaccatct gaaaggccat gaaaaatttc aacttcccat tcggaaatag tgaaaaatga
    34741 tccacaatat tggcaaggct ggcatgaccg acatgcgttt caaagcccgt tagaaccata
    34801 aaaacggctg ttgcaatcaa ggctaaaatc gcaacaatct taatcatggc aaaccaaaat
    34861 tcagtctctc caaagacccg cacagcaatt aaattgatgg agctaagcaa caccaaaaaa
    34921 acgagctgaa tcagccaaga tggccaagca ggaaaccaaa actgaacata ggaggcgaca
    34981 gctgtaatct ctgccatgcc aataaagatc agggaaatcc agtaagaaag cccagaaaaa
    35041 tagccccagc ctggcccaat atattttgta atgaaattga taaaggtatg ctgatccgga
    35101 tcatagtata gcatctcacc aatagcccgc atcatcaaaa acataaagac acctgtaatc
    35161 atgtaaacaa agataataga cggacccgtt aaggcaatag aacgaccagc tcctagaaag
    35221 agacctgttc caatagtgcc tgctatcgca atgagctgaa catgtcggtt ttgcagcccc
    35281 cttaccatgc cattctcaag ttctttagtg cttttagctt cttttgtaga catttgactc
    35341 tccattcaat taaaaaaaca ccactattat atctgttttt cagaaaatgt tcaactttct
    35401 ctaaggcttg caaactaaaa aggccaacca agccttttta gcgttaacct ttttaagatg
    35461 ataggctttc aatgtaatgg tagacgcctt gaccggcaat ggcaccatct ccaactgctg
    35521 ttgtgatctg acgcagctgc ttttgacgaa catcaccgac agcaaaaata ccaggaatac
    35581 ttgtcttcat ttgatcgtct gtcacaatcc agccctcttg attggtaatg cctagctcag
    35641 ataccatttg agtaaccgga atcaagccga catagataaa gacaccacca aagtcatggc
    35701 tagtcacttg acctgttttg acattttcaa tcacaacatt agagacctta atatcgtttc
    35761 cttgaatctc cttgacaaca gaatcccaga taaaatcaag cttttcgttg gcaaaagcac
    35821 gctcctgcaa gatcttttgg gcacgcagct gatcacgacg atgcacaatc gttactttct
    35881 tagcgaactg ggtcaggtag atggcttcct caactgctga atctcctcct cctacaacta
    35941 ataactcctg attgcgaaag aaagcaccat cacagaccgc acaataagaa acacctcgac
    36001 tggtgtactc ctcttctcca gcaacaccta aaagacgatg ctttgctcct gtcgcgacaa
    36061 tcactgtttt agtatcgtag tgcgtatctt ctgtgtacac acgcttataa tcaccacaat
    36121 cctcaaccct ttgaacaatg ccataaatgt tttcaacctt aaatttttca agcggctcat
    36181 acatctttaa cgatagctct ggtcctgaaa tgtgatcata gccaggataa ttttcaatat
    36241 ctgatgtgtt attcatttga ccgccaggtg ccccctgctc aataatgcca actcgtaggt
    36301 tactacgtgc tgcatataaa gcagctgtca taccagcagg tcctgatcca ataatgagtg
    36361 tatcgtacat gggttaactc ctcttaatag tcttgtcatc attttaacaa tagctacatc
    36421 gtattgcaat tatttcgcct tcaataccac cagaatgctc ataaaggcaa aggacaaaat
    36481 cggaatcgtc aaaatagcaa ccataatcat ctcatataaa aatgcctgtc tctggagaat
    36541 ggttttatcc tttttggtca cagcacgcca taaaatccac aaaagacaaa gcatgaccat
    36601 cgtaatagct gctaacaaca gaccttccaa ataaaagcga aaaatttcta ctaacatctt
    36661 tatctacctg attaccataa ccttttttca tggcagctta gcttttaagc acatacaaga
    36721 aaagcctagc ctacctagac ctttttatta tatcaaaagc cggcttttaa atatacgttt
    36781 ttgcatagtt tgcaaaaaat tcctttgttc ttgcttcctt agggtgtcta aagatctgct
    36841 caggagctcc ctcttcaaga attttcccct tgtctaaaaa aagcacccta tctgcaacct
    36901 gataaacaaa agccatatca tgactcacta aaatcatcgt ttgacctgcc ttggcagcat
    36961 caataataga ccgttcaacc tctccaacca gctcaggatc caaggctgag gtaggctcat
    37021 ctaataatag cacatctggc ttcatggcta aagcacgcgc aatagcaacc ctttgctttt
    37081 gaccgccaga taaatgacga gggtaatggt tttcacgatc agacaagcca accttagcta
    37141 attctgctct agctatgtct gttgcttctt ggtcagacag ttttttaact atttttaatc
    37201 cttccttgac attgtcaagc gctgtgcggc gttcaaagag gttaaattgc tgaaagacca
    37261 tcgctaattt tcgtctaagc gttagaatgt cttcttttgt gatgtgttca aagtcaactg
    37321 caaagtcatc aatcgtaata cttcctgtat ctggctgttc aagataattc atgcttctaa
    37381 ggaaggttga ttttcctgca cctgatgcac caaccagagc tataacctgc cctttttcaa
    37441 tcgtcaccgt taaatcgtct aagatctttt gtccagagaa ggacttggtt aaatgagtta
    37501 ccttaatcat tagcgcaatt ctcctatctt gctattattt gttgggattg gtgctttgat
    37561 agccatgtta tattcaatta ggcgaccagc ctgttctatc aaaatactaa tgccccaata
    37621 aactaaggca actgagatgt aacgttcaaa ataacgataa tctgctcccc ctagaatctg
    37681 tgcctgtgca aacatttcaa cgatacctgc attgaaggcc agagaggttc cctttgtcag
    37741 gcctatcaac ccattaatca aggtcggtgt tgccacaaca gcggcatttg gaatgataac
    37801 tcggcgataa acctgagcag aggtcattcc taggctctta gcagcctcaa tttcgcctgt
    37861 gtgaacagat tgaatcgcag ctctaatggt ttcactcgta taagcagctt cattgaaggc
    37921 aaaggcggta atcgcaaaga tagaagccgg aatagcgttg atattccaat caaagccata
    37981 gcgttgattt aagaatttca gaaaaagagg aataccatag tagctcagca ttagctgaac
    38041 caatatgggg gttccacgca aaaagctaac aaaaaccgct tgaatcggat aaagaatgcg
    38101 aaccctgttg attttgacaa tggcaaaaac caaggccaaa aaaagaccca aggcagcacc
    38161 agctatcgtc aaaccaagtg tgattggcag acgcctgata atatctggaa tggcatcaaa
    38221 aacagcatgc cagctaaaca gcttcccttc tgggatcaac gagatgagct tgtcatacca
    38281 agcccaccca cttgttaaaa acgtagatgt catgtatcgc ccctttatac tggtttgtct
    38341 caatattttc attttaacat tcttgagatg tcatgtaaaa tagtaaatcc gcatgataat
    38401 gataagaaaa gcctatcgca gaggatagga ctcaaacaaa ggaaaaaaac tctttgaaat
    38461 accgttaaca gtagcctctt ggagctacca agcttgaact tgagccgaac tctcaaagcc
    38521 tccaagtggc taattctcaa agaatatagc cactggtaca agactaacaa tcagctacta
    38581 ggccaaaaag gtcaaaagct tggctagctg gcacagctaa ctgcctcaaa ggctaggtca
    38641 acgaaagatt gaagcctgcc cagggcttga gggcttttag ccctgtcaat taattgacct
    38701 tggagataaa gtctcctccc aaaaatgctt ggctgagctt tctgagctga cctgattttt
    38761 taagcttagc cagccttttg ttgacaaagc tctgtagagc cttacccttt tgatcattgg
    38821 caaacacata atattccaag ccatccttag cagtatcagc ctgctccttg agctttgtca
    38881 catgcacatc aaagccttgc tcctcagcta cggttgttag agaaatagcg tcatagaaaa
    38941 gaaagtccag ttgaccattc tccagcagct gcagcctttg agtaaatggg gttgactcag
    39001 aagcataggt aaggtgaata ggcttttggt caggatggga ttggttccat ttttcaagga
    39061 taagcatgta attggagcca gctattcctt gggttttctt tccagaaaga tcagctaagc
    39121 ttttatactg ctgcttaccc tttgttgcca gagcataatg cgaggccgaa atagggcttg
    39181 aaaacaaata cttttcagct ctttccttac tatagccaaa attattggcc ccaatctgat
    39241 aacgacctgc atcaatacca gccaggatcg atggaaaagg aaccacctct atgcttaacc
    39301 gatacttttt ggagccttta aaaacccttt ttagaacctc aatatcatag cctgtaacgc
    39361 tatgcttctt cctataggta aagggcttag tggcagcatc tgttgctact ctgatcacct
    39421 ctttttgacg agctgtgacc tcatggctag tcacgactgc caagagtcct agacttgcta
    39481 gcaaaaaaaa gagtgctcgc tgtaattgtt ttgtcatacc atactcctat ctcttataca
    39541 gtagccattt taacaaaaaa tgataaattt gaataatatc atttctctat caaggcaata
    39601 agaaaatagt atcaaacaag caattaaaac agcacattct tcatttacct gatcatggat
    39661 taaccacaac agacaagctt tagctattag caggctgcct aagccaaaat caacacctca
    39721 agctttcaac tgactgatgt aaaagctagt agtcacctct acaagaagaa aaagaactgt
    39781 ttgtgtcatt caaccagtag cacccttctt aactggtcat tcctatccag ctctactact
    39841 aggctgtcag ttaacgatca gaaaaaaagt tgacctatct gccttatgaa gcctagaaaa
    39901 ctagctttca ttctgtttaa cattagaaaa cgagtaaata gtttaaaata aatttttatt
    39961 attaaacttt aactgttgct atattaatct ttttacatta taattaagta taaggaggtt
    40021 ttctatgaaa aaggcaatag tatcggttac tttgttaaca gtagctgttt taagcttatc
    40081 aacaagattt atctactcca ctgattattc tgatttaaat cataaggaga tggcacgtct
    40141 tatccagtca agaaaacaac cagtaattaa gtatcatgac aatgtaacca ttaataaaat
    40201 gattacttac ctagctcagg ctaaaagaga aggcattctg acagagacct tcctcatgaa
    40261 ttatattttc gctggagagg gtgagtacct gactaaaaat tcaaggatta ttgccgatcc
    40321 tgacggaggg tattggagta tcctagaagg ttatgaggga gatggcggtg ttaagactgg
    40381 tattgacggc gtctcagagc tcaatatctt tagtccagaa tctaccagca tcggagagct
    40441 tcaagaagcg gtgctagcct ggtatgaggc taataagtaa ccgcagctta gttaaccgac
    40501 tgcttcatat aatagctaat attagctaat cataggcctt ataggcattg aaatggtcag
    40561 acccatgctc aatgcttata aggtttttta gtgcttacca tctaaccaaa accatagcct
    40621 tcagagagac attgagctga acaagcaaaa aagaggagca agctcctcct caaacattaa
    40681 tacaccttaa tctacactcc cacagaggaa gtaatttaag gctggtgtgt caaagcgtat
    40741 caacccgtta atttcaatca ctattctgac agccaaaggt gcggctttag ttgttaatag
    40801 ctggttttag ttgccacgct tcaaagatag ttgctgtaac aattgaagta ggttcgacaa
    40861 tttcaaatgt aacaatactt ttatcacacc ttttgcggga gcgtagattg aaatccttgc
    40921 acgcaacgac aggaccattt gacatgggac actgaacaga gttgaagcct ttaaaaacaa
    40981 tccctaaaca gctttgggac ctaatcacag ttccttgact cagctctgtc aaggattctg
    41041 ttcatatcag cttagaatga tcgctaaaaa ctttttgatc taatttttct tgaacggatg
    41101 atctttacca agcacctgtc ttaaaagctt tgctttctgg actgacgctc tgctcgtccc
    41161 ttggcacgtt tttctgctcg tcgctgcttg cgccgctttt catcaactgc ccattgaatt
    41221 ttctttttat agcccggttt aatttttttc ttttttttct taaccaggcc aatcatttca
    41281 gtgtctaatt tctgataagc tttttcacga ttctggcgac gatcacgatc gtaagtatcc
    41341 tgaaactcac cattttttaa aacctttggt ataaaggtaa tgcctagctt ttccagctcc
    41401 ttgatatcag aatcatcact tggctgataa aaggtaatgg ctgtccctgg caggccgttt
    41461 ctacctgtcc gccccacacg atgcacaaaa aaggataggt cttgaggaat ggcgtcgtta
    41521 atcacatgac taaccccctc aatatcaata ccacgcgccg ccaaatccgt tgccacaatg
    41581 tattcaaatg ccaggttttt gacttgattc atgatacgct tgcgctctct aggaggaata
    41641 cctccatgaa gcttggctgc cttcatacca ttagctgcta aaaaggcatg taagtcatca
    41701 gctctctcct tggtattgac aaaaagcatg gccagataag gctggatagc ctttagagtc
    41761 gccaaaattt gctcattttt atcgcgtccc ttggttgata acagccagtt gtcaatcgta
    41821 tctgcaataa cggtttctgt cttgatctgt tcaatgacag gattggtcaa atacttcctt
    41881 aaaaagggct gtagcttttg tggaatggtt gctgaaaata caagtatttg gatagtcttt
    41941 ggcagtgctg aagcaatctt atccacagtg cttaaaaagc ccatatccat tgtcatatca
    42001 gcctcatcaa caacaaaggt agaggcctta tgaatggcta aatctcctga cttgactaga
    42061 tcatagatac gacctggcgt tccaatgaca agctggggct gactaagctt taacttgtca
    42121 agctgacgct gcttgtctgt ccctccaacg taattagcaa tacgaatctc ctgcttagaa
    42181 tgcttagcaa tttgcctgct ggcctcaaaa atctgtgttg ctagttcccg gctaggtgct
    42241 gtaatcacag cttgaacctc ttctttttcc tccttgagct tttcaaaaat aggcagcaaa
    42301 aaggtatgcg tctttcctga gcctgtcttt gactcaccca ctaagtctcg tcctgtactg
    42361 acaatcggga taagacgctg ctgaacctct gttggctcta caaagccaag ctcatctagg
    42421 gcctcttgaa tataatgctt aaagtgataa tcgtgaaatg acattattta cctcgttttc
    42481 tttctgataa tactattagt gcttgagatg agcaaaaggc ggtgcctcaa gcactgcccc
    42541 agccgcttac aaataaagaa tcgctaaaac aatgagactg gctacaagac caagagccca
    42601 taggaaggca tcaaccttcc attcagacca cttggctgct ttaccggaca agccgcctaa
    42661 ttccagatga tgatgaaaag gagtcatcct aaaaatccga cggccttcac catatttttt
    42721 cttggtgtat ttaaagtaag taacctgaag catgactgag cttgtctcaa gaacatagac
    42781 aatcccaata accagcaagg tccattcctg acgaagcgca atagaaatcg ctgctagcat
    42841 tgctcctaag gctaagcttc caacatcacc cataaaaatt ttggccggct tatggttaaa
    42901 caagaaaaag gccagcaagg caccaaccat gatacctatc aagagcaaaa catcaaattg
    42961 tccctgagca taagcgataa caccataggc cagcaggcta atcacaacag ataccgaggc
    43021 cagaccatca ataccgtctg tcaggttgac cgcatttgaa aagccaacca cccaaaaaag
    43081 aacaaagcat aggtataaaa agcccaaatg ccaatgataa ccaaagacat taatcgcatc
    43141 aataccactt ggcatgacgt gtatcacata aaagaccagg cctccaacaa tctgaaacgt
    43201 gaatttttgc ttggcagtaa ggccttcatt aacctgcttg aagatcttta agaaatcatc
    43261 taaaaagcct atgatcccgt aaatcaatac aatcaacaag atccccgaaa tcaagcctag
    43321 gctttgtcca tctcgaaaat agactaaagc aaacacaaag gataagcttg tagcaacaag
    43381 aagaaaaact gttcctccca ttgtaggtgt tccagcctta gccaaatgct gcttaacgtc
    43441 ctcatgcatc tgctgccccc caattttttt caactggtaa agccttataa agtgaggcat
    43501 ggcaagggca gtcacagcaa aggctatcag acctgctaga atggttaaaa acatgttaat
    43561 ctcctaaagt tatggtaatt tttttgactt ttttgagcgc ttttccgaca tcaacgctct
    43621 gtttaacgac acgtcccgag cttgatccct tgtacttgat atcaatgcca gtccatttag
    43681 caaaggtagc cacattagcc ttagtccagc cgtacatatc aggcatctca tcaaaatgat
    43741 ttgataaaat cagaagctgt tggttagcag ctagattggt ccctgccttt ttagatacct
    43801 ttttaatctt gctgccattg ccaaggacaa tagggtgaac cagatttctg cgtagctcat
    43861 cagctgattt tcctgtatct tggccaacaa tatcaggcaa ctgataagta gcctcgtgac
    43921 tggtatctac agcaaccggc ttgtctaaag tatccttcat caaataggct tcctctaaaa
    43981 cagggttgat aatatcctgc caaaacacca ttgcccaatg ctctgggtgc ttcagtgtga
    44041 catacatcag aaaatcaggc tcatcagctg gcaccatagc aaccaccgaa taaatatagt
    44101 ttgtcaagcc accatctaaa taacctgtac cgtccttagt cgcaatctgc gcagtccctg
    44161 acttgacagc aactggtaat tgaccaacct taaccactgg acctgatgat ttcaaatgaa
    44221 gggttccaaa ttgtgggtca gtcccaacgt taatcatgta ttttcgtgtt tcactggcag
    44281 ccttttggga caccggcttt ccgacaatct ccttgtctga cacccggtaa gtatctgtat
    44341 ttgggtcata aatgcgacta acaaattgag gctctagcat cacaccgtca ttagagatgg
    44401 ctgtaaaggc tctaagcatt tgaatttgcg tcaccgaaat cccctgacca aaagcgctca
    44461 ttgcttgggt aacaatatta tcagaaggga aaatacctgg gtcttcattt tccaagccaa
    44521 agcgtgtccg gaatccaaaa cggaatttag ttaggtagtt catccatttg tcatttccca
    44581 ttttttgctc tagcttggtc atgccaacgt tacttgaaaa cgaaaagcct tgagcatagg
    44641 tcatgtactg ccctgtagaa atcccttcgt taatcgccca atcctgaatg gtagcatcag
    44701 caatggttaa gccattcgca ttgctaaagg tctcatcagg attaaagacc ttctcatcaa
    44761 tagcagctgc cagagtcata accttcatgg ttgagccggg ctcaaactgc ccctgatgga
    44821 gaatattttg ccagctatag cttttgctgt ttagcccctc caaggtgtct gcattatagg
    44881 ttggtctttg agtagtcgct aagatttcac cagtcttagc atttactaga gtagcactag
    44941 caagctctcc ttgcgccttc gactgaaaga cgtccatttg cgtttctaga aaggtttgaa
    45001 taggctctga cagggtggta taaacgtcct taccatcaac tggctttttc actgtctttc
    45061 ctgttccaag cagggtatta ccgtttctat ccttttgata agtgatgatt ccatcttccc
    45121 cagataagat gctatcaaag gccgcctcca tgcccatctt tccaactagg ctcttggtac
    45181 cgtcctcctt gttttcctca agtgaagcaa gaccaatcag ctctgaagca aaggtcccat
    45241 ttggatacat acggctagga cttgctgaaa atgcgatccc cttgatttta gctgcctcca
    45301 tagccttttg gatcgttgtc atcgtgctat aagaaatacc tgagccagac ggaccaaagg
    45361 aaacctgaaa aagacctttt tgcttaagct gcttaataac gtccttttcc tccataccca
    45421 gctgctcctt gaggatttga gcaaccttgt catactgaga cggttgaaca aaaagcttct
    45481 cgccagtcgc tgacacaaag gacttatcaa gaatggcata aatgctatag gtcgtcgagt
    45541 ccacagcgat agctgtgcca ttgcgatcat aaatcgtgcc tcgcttggcc tgaacagaaa
    45601 ccgtctcttg ataaaccttt ttggctccat ctgatagctt aacaccgaat ttctgatccg
    45661 tcccgataat gatcataaaa ttaatcataa agatgaagaa aataaagatg gttaagagca
    45721 tcatgttttg ccccaccctc aagcggttct gaacaggtgt ctttcgatca cgaaccacat
    45781 aatctaaaaa atatctttgc cattttgtca tagcttactc gaccttctta atgttatcat
    45841 ttcggttact aagccctgct ttgccagcaa tatcaacaat gcggtcacgt cgcgacagct
    45901 cattaacctc ttgcttggca ttgttaagct ctgtcctttt atctgagatc tgcctattga
    45961 gctgagtgat atgctgctgg agctgcaatt tacggctttg caggtaaata atgcttacag
    46021 ccatcgttac tgctgtcagg ataagcgtag cataaaaagc cttctcaacc ctcgagaaag
    46081 ttctaattct tttttgcaag gcttttgaaa ctgcctgagt tcttttttca ttaaccataa
    46141 tctatttccg aacttttctt gcgactcgta gcttggctga atgtgcccta ttgttagcca
    46201 ttagctcctt ttgacttggt aaaatcggct tacgcgaaac caattcaagc ttaggcttga
    46261 gctcatcagg tataaaggga agtccctttg gagcatcagc tgtgcttgct tctttaaaca
    46321 agtgctttgt cagacgatcc tccaaagaat gaaaggtaat cactgagata cggccatcaa
    46381 gggctagcag ctctatcgcc cgctggatag acgcatcagc agcaccaagc tcatcattga
    46441 cctcaatacg aatagcctga aagatttgct tggctgggtg tccttttttc ttgagctcct
    46501 tggctggctt agctgatttg atcaatgctg ccagctctgt ggtggtgctg attggcttaa
    46561 tggctctcgc ctgctcaatc ttacgagcaa tctgctttga gaacttatcc tcaccatatt
    46621 taaaaaagat ccgaactaag tcattgaaat cataggtatt gacaacctca taggctgtca
    46681 aagccgcctg gctatccatt cgcatgtcca agggagcgtc ctgcttgtaa gaaaagccac
    46741 gctctctctc atctaactgc ggactagaaa cccctaaatc atacaaaatc ccatcaatct
    46801 ctgtaacccc atgctccagc aagcgtgcct taaggtgtct aaaattgtcc ttaataaagg
    46861 tcacctgtcc cttgtcaata tagggcttga gctgctcctg cgcgtgatca atagcctttt
    46921 ggtcctgatc aaagcaatac aagtgcccct tatcaccaag cagagacagc aaataagctg
    46981 agtgcccaga gccaccaagg gtcgcatcta cataaatacc atctggctta atatccagca
    47041 tatcaacagc ttcatgaaga agtacagtta catgatgaaa ttcgtttgtc atagctctaa
    47101 ttgtaccata cttcaaaggg tttataaatc aaaaagtaag agaaaagggc tttcaaggcc
    47161 taagaaagtc cctctttatc ttactttttt tggcttagct atccttgaca tcaagatgac
    47221 taagagcttg ctgcacagcc tcatacagca gctcagccga ttcgagcacc tgcttggtct
    47281 cctttaacac ccgaaaatct gtcaccgaat tatctagcca aatatcaaag atcttatcct
    47341 gtcttgtatg agataagcta gaaggcaagc gcaactcact aaccttcagc tccttttgat
    47401 acctacagac cagatttctc acgtccccta ggctctcatt aatagcactg attttttgcc
    47461 tttttaccca gcttgttagt atcccattgt cgaacaaatc aaaaaatccc cacctcttaa
    47521 gctctttcaa tgcctcaatg acagactcaa gcttaaaagc taatgtcttt aggtctcgta
    47581 tggtttcttg cttctttaga tcccttgtca taagcctacc tccttagcag ctagctccga
    47641 atctggccat ttccattgat caggtattta ctgctggtca aggcctcaag tcccatcggg
    47701 ccacgagcat gcattttttg tgtggaaatg ccaatttctg ctcctagacc aaagacaaag
    47761 ccatctgtaa agcgtgtcga ggcattcaca taaacagctg ccgagtcaac cagatcctga
    47821 aaacgctctg cagcattgat attagctgtg atgatggctt ctgaatgatg actggtatac
    47881 tgattaatcc aagaaatagc ttcatcaaga gaggaaacca gatgaacaga catgatataa
    47941 tccaaaaatt cagccgcata atcttcctct gtggctaata cagccttgct aaacaaggct
    48001 tttgcctgct catctgctcg ccattccacc tgctgaacct tgctgatggc tgcttcaagc
    48061 atgggaataa aggtcgctcc taccttctca tgaataatca ggctttctgc agcattgcag
    48121 acgcttggtc tttgcgtctt agcattaatc acaaccttaa cagccatctc tagatcggct
    48181 gcttcatcaa cataaatgtg aacattgcca acccccgtct caatgactgg caccttagcc
    48241 ttttccttga ccgtttgaat taatctggca cccccacgag gaatcaagac atcaatataa
    48301 tccgttgcct gcatcaattc ctcagctaca gcatgagagg tatcctcaac cagcaaaaca
    48361 gcatctggcg taatagctga tgcctctaag gcatttctga taagcctgac caaggccata
    48421 ttagagtaga gagcatcttt gccacctcta agaataatgg cattattggt cttaaaggcc
    48481 aagctaaagg cgtcaacaga aacattaggg cggctttcaa aaatcatcgc aataacacct
    48541 aaaggcacac gcttttgggt tattttcagg ccgtccagat ttgtatagcc cttaatcact
    48601 tcgccaatgg gatcagccaa gtctgccacc tgtctgacgc cctgagccat cgcatggata
    48661 cgatctgctg tcaggcgtaa gcgatcgcac agaatctctg aaatcccatg ctcagccgcc
    48721 ttagccagat ccttggcatt ttctgtcaaa atcatatccg tctgggccac taattcctca
    48781 gccaaaaagg caagaaattg atttttatcc ttcgttgtca aggataccaa ggccctacta
    48841 gctgccttag ccctttgtcc tagctgttct attgtcatca cgcgtcacct ctttctatct
    48901 gtttaaacca agtgcctagc ttttctccct ccaagaccct taaaatgtct ctagggttgg
    48961 caccattcat caaaatcatt tgcccctgat gctcaaacat catctgggct gattggatct
    49021 tacttagcat accaccagtt ccaaatctgc tgcctgcacc gcctgctgag gctataatat
    49081 cctctgtaat ctctgtcaca tgactcctca agcgcgcgtc ctcatagatg gttggattct
    49141 tatcaaacaa accatcaatg tctgatagca taatcagcaa atcagccctt gtaatacgag
    49201 ctacgatagc tgataagcgg tcattgtctc caaattttgt tgaatgatcc atctcatcaa
    49261 cactaacagc atcattttcg ttgacaatgg ggacaatccc taaactaatc aggctttcaa
    49321 aggcattggt gacatttgcc agactttctg gaaaaacaac cacatcacgt gtcagcaaaa
    49381 tctgagacac tgtcgtctga tagtgggcaa aaatttgcga ataaaggctc atcatagcaa
    49441 cctgccccac acttgaaaca gcctgctgct tggcaagctg acttggtctt ttggccattt
    49501 tcaacaggtc aagcccaaag cccatggcgc cagaggaaac caaaataacc tcttttccct
    49561 tattcattaa gcttgaaatc acaaaggcta aatggtcgat cttttctaag ttaatcttcc
    49621 cattagcaag caccagcgag ctggttccaa ttttaattac aatacgcttt acatcttcaa
    49681 attgtcgttt catcatatta ggattatagc ataaaaaaca gcccagagga ctgttagatt
    49741 gaagccaaaa tcaatcagcc tatcagcttg ataaaaaaaa ggatcactgg ctacccattc
    49801 acctaagata taaaaatcca cctgatagcc actccaagca ggatttcctt tgtgacacca
    49861 cataccacgc tacgctttat cctattgtaa gtttaagtct gatcctcctg cattgtcctg
    49921 tcatttttaa tgaccatata ccaacactaa agctattgac aaaaacgcac aatacgataa
    49981 aatgaaagcg caaacagcta tatttactac ctaagggcca gaccttgctg taaagcgcaa
    50041 tacctgacag aaagaacacg tttcagaagt agcaagaaca agtcacaggc atactgtctg
    50101 gcacattggc gcaaaggcta ccagtgttca acaagactgg aacgcaaatc aataggctgg
    50161 aaatcaagta ggaaaaccgt atcatttaaa tttttggaat cccaagactc aattgttctc
    50221 aattagtttg ggggcttagg acgacagagc ctgtcagtca tctaaagcaa ttaattagtt
    50281 ataggaataa atcactatgg ttaaactatc aaaaagaagc aagatagcta tgtcattttt
    50341 aattgtcttt tgtggtatat ttttcgtcgc tcaaaaacga ttcggttcat cagaccaatc
    50401 atttaccgta aggccagacg cagatttcta tatagtcggt taccacaata ttgaaggtta
    50461 tcaattgaca aatgagcagc cgcaaaaaat ttctgacgct aagctcgaag tggtcaaagg
    50521 tcagatcaat caagtggtta aacgagcaga gctttcaaat cgttatctgg tcttttccga
    50581 ggaggggcca cctttggggg caataggaag acttatcgct cttgattttc aaaaaggcaa
    50641 cgtgacgtat cacccaacag ctgattatgc ctttacttcc tccggagtat caccagatta
    50701 ttatttcact tctacagcaa
//
LOCUS       DARYMD010000008        50125 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYMD010000008 DARYMD010000000
VERSION     DARYMD010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50125
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(335..694)
                     /gene="rplT"
                     /locus_tag="TU818_000412"
     CDS             complement(335..694)
                     /gene="rplT"
                     /locus_tag="TU818_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL0923268.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(755..952)
                     /gene="rpmI"
                     /locus_tag="TU818_000413"
     CDS             complement(755..952)
                     /gene="rpmI"
                     /locus_tag="TU818_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL0923269.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(992..1522)
                     /gene="infC"
                     /locus_tag="TU818_000414"
     CDS             complement(992..1522)
                     /gene="infC"
                     /locus_tag="TU818_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL0923270.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(1537..1659)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(1683..2363)
                     /locus_tag="TU818_000415"
     CDS             complement(1683..2363)
                     /locus_tag="TU818_000415"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL0923271.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAKRPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVNQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIAADFDTLKAEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(2378..2875)
                     /locus_tag="TU818_000416"
     CDS             complement(2378..2875)
                     /locus_tag="TU818_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL0923272.1"
                     /translation="MAKEPWEEKIVDDNKATRTRKSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKKTTKKVSSKPKTKPKASSNSSAASDTTS
                     PSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYANPGD
                     EVNIK"
     gene            2924..3121
                     /locus_tag="TU818_000417"
     CDS             2924..3121
                     /locus_tag="TU818_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL0923273.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(3108..3596)
                     /locus_tag="TU818_000418"
     CDS             complement(3108..3596)
                     /locus_tag="TU818_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL0923274.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAILVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(3641..4864)
                     /gene="pepT"
                     /locus_tag="TU818_000419"
     CDS             complement(3641..4864)
                     /gene="pepT"
                     /locus_tag="TU818_000419"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL0923275.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(5034..6053)
                     /gene="galE"
                     /locus_tag="TU818_000420"
     CDS             complement(5034..6053)
                     /gene="galE"
                     /locus_tag="TU818_000420"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL0923276.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVVDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKKIIFSSSATVYGDPHTVPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(6121..8490)
                     /locus_tag="TU818_000421"
     CDS             complement(6121..8490)
                     /locus_tag="TU818_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL0923277.1"
                     /translation="MLDMILFSLSSLYLSIFAVSKNTLNKGAYGSWLVLVLIAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALVSL
                     LILGVLLKKYLFKKDYQSNRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSN
                     LVSLNLFKYSFCSYMLTFVVYYLIVTAFIEVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFVLVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQIISIILILVLSGLLIYVLYKRYFREK
                     ILSALYLRLMSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIAEIHHIMETTTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKFSPAISNAFSPKDRIVLHLASANNYSRKIVYNKLGFD
                     TFIATEDSADKPKHLIRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDQSETDSLQSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEVKYLTDYFIWSNHQTNKLARPRVNSSDFTSLLLEHTDSKVSPYYALL
                     TDVLDTRNSDDSQLTAAQKQVASDLKLLEYDLIEGKGYINAYPDFFKMK"
     gene            complement(8570..9733)
                     /locus_tag="TU818_000422"
     CDS             complement(8570..9733)
                     /locus_tag="TU818_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL0923278.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKAIPSIVIEHGGGYVQVGENVKGHQLLDLFAKVYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYEVFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLASLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCDLQEAIHQQVLSGFTWEVTVRQLVTEVIASESESNV"
     gene            complement(9747..11231)
                     /locus_tag="TU818_000423"
     CDS             complement(9747..11231)
                     /locus_tag="TU818_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL0923279.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLAIL
                     VAIAALLIIFLPSNMEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSKLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     VIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRNPIVYGFMLLRHTLAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPTLSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILGMITRTMLQYYT"
     gene            complement(11235..12476)
                     /locus_tag="TU818_000424"
     CDS             complement(11235..12476)
                     /locus_tag="TU818_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL0923280.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQIRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICLISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDEKSFAQLERRLSLVLLLASLAILLASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARSFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(12460..12816)
                     /locus_tag="TU818_000425"
     CDS             complement(12460..12816)
                     /locus_tag="TU818_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL0923281.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(12821..13510)
                     /locus_tag="TU818_000426"
     CDS             complement(12821..13510)
                     /locus_tag="TU818_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0923282.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSINAGADCVIGSRFVSAEKNRSLRMIGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(13540..15285)
                     /locus_tag="TU818_000427"
     CDS             complement(13540..15285)
                     /locus_tag="TU818_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL0923283.1"
                     /translation="MKRLLLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMKPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTTYPASLIVDHMSQVHPPDAKYLLAHKYLPEQ
                     PISIDQSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKEILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKR
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLSQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(15282..16289)
                     /locus_tag="TU818_000428"
     CDS             complement(15282..16289)
                     /locus_tag="TU818_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL0923284.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     YSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQSNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEADLMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRMTDNSDSR
                     PAAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHQL
                     RQTLADQEALQAEKIDQLQQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(16310..17518)
                     /locus_tag="TU818_000429"
     CDS             complement(16310..17518)
                     /locus_tag="TU818_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923285.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNAEQGAAAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSHLNDIKLKLEVTVRDQNGQMLLFLTANHSPLVVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(17518..18321)
                     /locus_tag="TU818_000430"
     CDS             complement(17518..18321)
                     /locus_tag="TU818_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923286.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFVELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(18321..19256)
                     /locus_tag="TU818_000431"
     CDS             complement(18321..19256)
                     /locus_tag="TU818_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0923287.1"
                     /translation="MKINILMSTYNGARFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRICLINADVQENLGVIRSFHTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKISEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMINHALAEQWVSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLNPADRRLIEAYVGLLDRPFYQ
                     RLSDFKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(19246..20400)
                     /locus_tag="TU818_000432"
     CDS             complement(19246..20400)
                     /locus_tag="TU818_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL0923288.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKSYPWAKTTFIAYGTEIGRSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFVGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(20525..21373)
                     /gene="rfbD"
                     /locus_tag="TU818_000433"
     CDS             complement(20525..21373)
                     /gene="rfbD"
                     /locus_tag="TU818_000433"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL0923289.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGQKPAGQEWLETDTPDPQTAYGRAKRLGELAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCHLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(21515..21853)
                     /locus_tag="TU818_000434"
     CDS             complement(21515..21853)
                     /locus_tag="TU818_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL0923290.1"
                     /translation="MTETLKYTEEQVAAIKDRILEALGTVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(22151..23260)
                     /gene="rpoD"
                     /locus_tag="TU818_000435"
     CDS             complement(22151..23260)
                     /gene="rpoD"
                     /locus_tag="TU818_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL0923291.1"
                     /translation="MAKEKEITTFNVQIAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(23269..25083)
                     /gene="dnaG"
                     /locus_tag="TU818_000436"
     CDS             complement(23269..25083)
                     /gene="dnaG"
                     /locus_tag="TU818_000436"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL0923292.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTVAPSQTSLSQKQHPHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEYFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAIYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNTVASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QQGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFYFDTPAL
                     QTLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSRQMTLLK
                     QRELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            25330..25704
                     /gene="mscL"
                     /locus_tag="TU818_000437"
     CDS             25330..25704
                     /gene="mscL"
                     /locus_tag="TU818_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL0923293.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(25930..26106)
                     /locus_tag="TU818_000438"
     CDS             complement(25930..26106)
                     /locus_tag="TU818_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL0923294.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(26261..27073)
                     /locus_tag="TU818_000439"
     CDS             complement(26261..27073)
                     /locus_tag="TU818_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL0923295.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQEKGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKVD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLVGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(27141..28256)
                     /locus_tag="TU818_000440"
     CDS             complement(27141..28256)
                     /locus_tag="TU818_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL0923296.1"
                     /translation="MKLPVFGVEEWLNQHEKRAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFTSDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEARASYHRPNEVSTAFVRLDIDEDMEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKNIQ"
     gene            complement(28526..32167)
                     /gene="addA"
                     /locus_tag="TU818_000441"
     CDS             complement(28526..32167)
                     /gene="addA"
                     /locus_tag="TU818_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL0923297.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDCLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFTDIPDQAVDALLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVRFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEGQRQPYPNNRAQLLLYDTDQVQEGTEEALANDGISAGEVILVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     ANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIAATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKTFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQTLQLVSAD
                     AEVKARLDIEKVTSFFATTELGQLLQEHHQRLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDRYQQSAELKQRYQQQMDLYAEALSQSYGIARIEKYLVLMGG
                     SQLEVVRLA"
     gene            complement(32157..35378)
                     /gene="rexB"
                     /locus_tag="TU818_000442"
     CDS             complement(32157..35378)
                     /gene="rexB"
                     /locus_tag="TU818_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL0923298.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSKLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRRETDREKDEEVWKAFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQ
                     ELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFS
                     SQQPLNLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     SNAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGLQI
                     TKQEEAFELALGQQVLIRGVIDRIDQLADGRLGIVDYKSSARVFDIVAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(35587..36987)
                     /locus_tag="TU818_000443"
     CDS             complement(35587..36987)
                     /locus_tag="TU818_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0923299.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGTIHLYERRQ
                     QAPVGGDVSLPPVSILVPAYNEELTIIETVESLLMLDYDCYEIIVIDDGSTDHTAKLL
                     KEQFHLEAVTCSINQRIPTRPLKAVSQKQLKHIKLTLLEKANGGKGDSLNLGINAAQY
                     DYLLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCHNNKIPYRIGYETDAICWSQAPSRLKDLCRQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIEAFGVIIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRVYLQNNSSITLFDMAWVIYAAIYQCLVLHTVLTLIKVSSFIGYQR
                     KKNAWGQITRDKHRAA"
     gene            complement(37129..39270)
                     /locus_tag="TU818_000444"
     CDS             complement(37129..39270)
                     /locus_tag="TU818_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923300.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYT
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRRRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPVTFYHALRRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLLGYIVGDDWYSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLTDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAADEWSRALTYKKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVIAMVEY
                     PLLSWERPRVREVLKTSYQQVQAVWQEKRRR"
     gene            complement(39277..40710)
                     /locus_tag="TU818_000445"
     CDS             complement(39277..40710)
                     /locus_tag="TU818_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL0923301.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKRAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(40716..41393)
                     /locus_tag="TU818_000446"
     CDS             complement(40716..41393)
                     /locus_tag="TU818_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL0923302.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQSVKNTTSDDIEMIFELSRKDYDSTYQQANPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(41407..42102)
                     /locus_tag="TU818_000447"
     CDS             complement(41407..42102)
                     /locus_tag="TU818_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL0923303.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSNQKKRSLRLTRA
                     DAQLLIKGDKSILLTYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(42230..42865)
                     /locus_tag="TU818_000448"
     CDS             complement(42230..42865)
                     /locus_tag="TU818_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL0923304.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQTDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(42855..43394)
                     /locus_tag="TU818_000449"
     CDS             complement(42855..43394)
                     /locus_tag="TU818_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL0923305.1"
                     /translation="MVKGVLRGDKLLEFEDIYLEYKDDVYRFVNKLCCYQNSLSDDIT
                     QETFLKAYRNIAKFSGDSSIKTWLFTIAKNTFFTEIKKKKYENMSMESLEIVDAKGHD
                     EPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAKDIGITVSSAKVLV
                     FRARKHIKRQLREEYGYEV"
     gene            complement(43683..47399)
                     /locus_tag="TU818_000450"
     CDS             complement(43683..47399)
                     /locus_tag="TU818_000450"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL0923306.1"
                     /translation="MMKRLGENQALFEERQLFGIRKLKLGVASVAIATAFSLGTASGQ
                     ITAAAESLTSVEPADGAVMVKSEAADQGSNELPEATDISDIAGISDVTKVSAAVNADT
                     VKEVQPVAVPLVEDQAHEETTDQSQPSSSIVSVTTDSSLETPEATSSEEPIAEQTLRL
                     HFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSANQ
                     ANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYRPLAQGYIRINYYRSD
                     GHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADTNELGFLLLDE
                     RQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNTVRLIGAQQVSPSSIE
                     ASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVT
                     FHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQ
                     TKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSL
                     AAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTS
                     DQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSS
                     SDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHT
                     ANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDG
                     FRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTD
                     TVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQY
                     IAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGR
                     TKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAKAT
                     DTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVI
                     AYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVV
                     LTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKT
                     LPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            47879..48424
                     /locus_tag="TU818_000451"
                     /pseudo
     CDS             47879..48424
                     /locus_tag="TU818_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            48505..48960
                     /locus_tag="TU818_000452"
     CDS             48505..48960
                     /locus_tag="TU818_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923307.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            48960..49247
                     /locus_tag="TU818_000453"
     CDS             48960..49247
                     /locus_tag="TU818_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923308.1"
                     /translation="MTTWYDYMVRASEHSGSDGDLWFRYLYKVIKDKETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            49240..49788
                     /locus_tag="TU818_000454"
     CDS             49240..49788
                     /locus_tag="TU818_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL0923309.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDIDA
                     FYQEGVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYDFQPDISMILEVFE
                     IAYGMEWLANYMTEHPEEFRHY"
     gene            complement(49967..>50125)
                     /locus_tag="TU818_000455"
     CDS             complement(49967..>50125)
                     /locus_tag="TU818_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0923310.1"
                     /translation="EAQKGDKPAVPKAMEHKLPSTGEATAPFFTAAALAVLASLGVAV
                     VSRKRKKH"
BASE COUNT        14858 a        11479 c         9517 g        14271 t
ORIGIN      
        1 tacaatgaaa ttatgacatt atggctccta aataagttgt tttgcatttt attattttgg
       61 tgatggattt gattaaaact agaaatcata tatctcctta tatgatcatc acttgatgga
      121 ctgctcaact gtctgataca agattaagcc ctttcttctt agttaacagc taccaaagaa
      181 aggtaaattg gctcctttat actaaattag agatagctaa aaacatctca aatactcttg
      241 acaaaacgtc atgactgtct tatctagcta gattagctaa cataaggcat taaaaataga
      301 cttagaaggt ttctaagtct acagtcgatc tctattattt gccaagcttt gccttagcag
      361 catcagcaag ggctgtaaaa gctgctgcat cattcaccgc taaatcagca agcattttac
      421 ggttaacttc gatttcagca agctttaggc catgcatcaa ttgtgaatat gacaagccat
      481 tcatacgagc agctgcattg atacgtgtga tccatagctt acggaagtca cgttttttct
      541 gacgacggtc acgataagca tagtaataag aattcatgac ctgctctttt gcagtacgga
      601 acaagatatg ttttgctcca taataacctt tagctaattt caaaatacgt ttacgacgtt
      661 tgcgtgatac aacgccacct ttaacacgtg ccattaatat tctccttcaa ataactctta
      721 taattctagt aaatacctgt tacaaccctt aatcttaaag gccagtaacc attgctttaa
      781 tacgcttgaa atctcctgca tgcaccatac ctgctttacg aagatgacgg cgttgctttt
      841 tagtctttcc atggaaacgg tgtgatgtaa aggcacggaa gcgtttcaaa ccgcctgaac
      901 ctgtacgttt aaaacgttta gctgatgcgc ggtgtgtttt ttgttttggc attttaatat
      961 tctcctctta acatatagtg taatatgaca attacttctt gtctgaaatt ggtgcaagct
     1021 gcataaacat ttggcgacca tccatttttg ctctttgctc aataatagca atatcttgag
     1081 ttgcctcagc aaaatcagcc agtaccttag caccaatctc cttgtgagta atcatacgtc
     1141 ctttaaaacg gatagaaacc ttaaccttat ttcccttttc aaggaactta cgaccattac
     1201 gaagctttgt ttcaaagtca cccttgtcga taactgggct aagacgtact tcctttacag
     1261 ttacaacgct ttgctttttg cgttgctcct tttgcttttt ttgatactca aatttgaact
     1321 ttccatagtc cataagcttg gcaacaggag gaacagcttg cggctggatt aaaaccaaat
     1381 ctacatttgc agcatcagct aaagactgag cttcagataa tggtttaatg cctaattgtt
     1441 caccttcaag accaacgaga cgaacttcgc gaacacgaat ctcatcatta atgaatagat
     1501 cttttttagc tatgatcttc acctctttat ttttttagag aaaaacgaaa gcggacttaa
     1561 tgaaccaagc ccgcacacat aatatcccgt aggaatttga catgtagggc cagacaacct
     1621 aggtcgcaag gcgagaagct ctcacttctg cttttctcat tattgacatt ctaacaaata
     1681 aatcatgcca tgtcaattat tttttctgct ttttcctgaa taaattggac aacagctgaa
     1741 atcgtgatac cggtagtatc aaagataatc gcgtcatctg ccgcctttag cggcgaaact
     1801 tgacgatgac tgtccttata atcgcgtgcc gcaatctcag cctttaaggt gtcaaaatca
     1861 gctgcaatcc ctttttcaat attttcctga taacgacgct gcgctctttc ttcaacagaa
     1921 gcaatcaaaa agatcttcaa ctcggcatca ggcagcacaa ccgttccgat atcacgaccg
     1981 tccatgataa tagcaccagt cctagcaatt cgtcgctgct gattcaccag ctcctctcta
     2041 atctctggca aggcggacac ccaagaaaca ttattggtga catcattttg cctgatcgcc
     2101 attgtcacat cttggtctcc aagaaaaacc agttgtgagc catcagctgc ttttttaaaa
     2161 gaaattggac gctttgccaa ttcttgcagg attagattga catcttcttt gtgataacca
     2221 ttttttaatg cgatataagt cgctgagcga tacatggcac cagtatctaa ataggtgtag
     2281 ccaagatttt tggcaataat cttggctacc gtacttttcc cacttgaggc tggtccatca
     2341 atcgcaattc taattgcttt catcttttcc tctttaatta tttgatattg acctcgtcac
     2401 ctggattggc ataccagtag ccttgggtca tatgatctgg gtttagggcc tgtaattgct
     2461 caacagaaat tccagcacga gctgcaatag atgttgctcc ttctcctgct aatactgtaa
     2521 ttgtctttcc tgctgcctct gtagaaggtg ctgtttcagt cttagaagga cttgttgtgt
     2581 cactagctgc tgagctatta gagctcgctt ttggctttgt ttttggtttt gagctgacct
     2641 tctttgttgt ctttttctga gttgatgccc cgtaaaatcc tgttgtctca ttttgcttgt
     2701 tactaccgct gtttgacgta tagaagaaaa taaaaagtat ggcaacaata atgacaaaga
     2761 aaacacttaa caaggcagtc aaccaaggtg tgctaatgag tgctcctctt gattttcttg
     2821 ttcttgtcgc cttattgtca tcaacaattt tttcttccca tggttcttta gccatgattc
     2881 ttcccccttg ttaatttaac aaaatcatat tagaataata cctatgaaag tatctatcct
     2941 tccagaaaaa tgcattgcct gtggtctttg ccagacctac tctgctcttt ttgactatca
     3001 tgatgatggt atcgtcaaat tggctcagtc tgatgagtca agtcaactca tagatcctaa
     3061 tgatcatgat gccatcttag cagtaaaatc ctgccctact aaagccctta ccctcgagta
     3121 agaggctttt tttcgtattg gtaggcttca aaataatcca gtttaatgaa gttatctagt
     3181 aatataacct ctcccttaaa ataaggatta atcgctagat catctaaaaa atatttttta
     3241 ggccattttc tcatgtaaaa aaggtagctc ttatcaccaa caaatagaca aaccgttgat
     3301 ttagtaacct caattttggt aattgaggca atcatcagtc tgtgcggagc aaatagcttt
     3361 aaagatacga tcttcaagac accattattc tcaattacaa aataacgatg caggccaagt
     3421 cccactaata tagcaaataa agcaaacaag acaaaaacac gactcggtat ttctgttctt
     3481 tcatacaata aggacaggcc aataaaaata ggcgcaacag caattgacca ataaataata
     3541 gaccaagaca gctctggctg ccaatgatac cttactttac cgaataattt aatcatgctt
     3601 ttccatcacc tccaatccgt tctgagcatt ttgggtgatg ttaagccttt tggacaatgc
     3661 caagaatcac atcaactgcc ttttccatcg tttgcagact cacaaattca aacctgccat
     3721 gcatattttc accacctgca aaaatatttg gcgttggaat ccccataaag gaaatctttg
     3781 agccatcagt accaccacga atcggctcga taactggctt aatagctagg tcctccataa
     3841 cagccttagc tagattcaca ggtgtcatgt ccttttcaat cacctttttc atgttatagt
     3901 actgatccgt cactgttaca aatacacgct ctgctccaag ctgactattc atctcctcag
     3961 ctagctgtgt tacaaaggcc tttctagctt caaaggagct atcctcaaaa tcacgaataa
     4021 tataagaggc ctgtgcttct tctacagtac cagacatgct gtgtaggtgg taaaagcctt
     4081 gatagccgtc cgttttttca ggacgatcgt caactggtaa ttgactatgg aaatccattg
     4141 ctagctgcag ggcattaatc atctgatttt tagctgtacc agggtgaaca ttgcgaccta
     4201 acaccttgag ctctagggct gctgcgctaa aggtttcata ttgtagctcg ccaagcggac
     4261 ctccatcaat agtataggca aagtcaacat caaaagcatt aacatcaaac ttatctgcac
     4321 caacaccaat ttcttcatca ggtccaaagg caaccttaat gtcgcaatgc tcaatctgag
     4381 ggttggcaac aagaaactca atagccgtca tgatttctgc aattccagat ttatcgtcag
     4441 ctcctaaaag ggttgtgcca tcagttgtaa tcagggtctg tcccaaatat tggttgagat
     4501 ttggaaaatc ctctgggcat aaagaatagc ctgactgacc aagcttaatc tccccaccct
     4561 ggtagctctc aataatctga ggggctactc cttctgcatt aaaatcagca gtatccatat
     4621 gcgcaataaa accaattttc cgagtcaatt tgctgctgtt agctggtaag cttccaatga
     4681 ggtagccatt agctggattg taatgaatgt cctgtaggcc aatagcttcc atctctggct
     4741 ttagcactgt tagagcaaag tcagcttgac tcttggtgct tggagttgta gtgcttgctg
     4801 gattgctcct tgtgttgatt tttacatagt tcagaaatcg ttctaataaa gtttcgtatg
     4861 tcatagatca cctcgataag ttttcgttac tattatagca taaaaggacc taaaatactt
     4921 gcctaagctc agttttttac agtgctttat ctgttctgtt acagttgcgt tctcataaaa
     4981 agacagctgc caagaaagct cttgacagcc ttgattattc atcagcccat gccttaatcc
     5041 tcataaccat ttgggtgctt gctttgccat ctccaagtat ctgtacacat cctttctaag
     5101 ccgtactctg cagtccagtt aagctctttt ttagccttgc tagcatcagc atagcaggct
     5161 gcgatgtctc cttgacgcct tggtaatatc ttgtaaggaa tagacctgcc aaccacctga
     5221 gaaaaggctt cgataatatc tagcacagaa tagcctgtac ctgttcctaa attataaata
     5281 gataggcttg gctcttcagc aaactttgca agcgcagcga cgtgtccttt agccagatca
     5341 acaacatgga tataatctct aacgccagtg ccgtccttgg tctcataatc atcaccaaaa
     5401 acgccaacac aatccagctt accaacagct acctgagaaa cataaggtaa taggttgtta
     5461 ggtatgccct taggatcctc tcctaaatca ccagactcat gagctccgat aggattaaaa
     5521 taccttaaca atacaatatg ccactcatta tctgatgcat agaggtcctt gaaaatctcc
     5581 tctagcatca gctttgtcct accgtaagga ttggtcactg atagtggaaa ggtttctaaa
     5641 ataggaacgg tatgcggatc tccataaacc gttgctgagg agctaaaaat gatcttttta
     5701 caattaaagg ctgtcattac ctttagtagg gtcaatgtgc cagagatatt attgtcgtag
     5761 taatcaagtg gaatcctgct tgactctcca acagctttta gccctgcaaa gtgaatgaca
     5821 ctcacaatag gatgcttact gaaaatatct gttagcagct gttgatcgcg aatatctccc
     5881 tgataaaagg tcacttctct tccagctatc gaggcaacag cagctaggct tttaggattt
     5941 gaattgcaca aattatcaac cacaacaacg tcatagccag cagctagcag ttcaacacag
     6001 gtgtgtgacc cgatatagcc tgcaccacca gtaactaaaa tacttcctaa cattgattat
     6061 atacctgact ttctaataat tactaatatt ataactgatt actcccaaaa agtatatcta
     6121 tcatttcatt ttaaagaaat caggataggc attaatgtag cccttgcctt caataagatc
     6181 atattctaac agctttaagt cagaggccac ctgcttttga gcagcagtta gctggctgtc
     6241 atcgctattt ctggtatcca agacatctgt caaaagagcg tagtaaggag acaccttgga
     6301 atccgtatgc tctagcaata aagaggtaaa atcactggaa ttaacacgag gtctagccaa
     6361 tttgttggtc tgatgattgc tccagatgaa ataatctgtt aaatatttga cctcctcatc
     6421 attcttaaag acctgatctg gataaaagcc aggtaaatga tcaccataaa acacaactgt
     6481 aataggcttg tcaacctttt ccagtgctga taaaaaggcc tttgttgact tgtcggtaat
     6541 gcttaataaa ttcacataac tttgcaggct atccgtctca gactggtcca gtcctgctag
     6601 gctaacatca acatctctta gctctgtgta ccaagggcca tgattttgca tggtaatcac
     6661 tgaaaagaat tgacttcttt tggggttaag ctggtctaaa atattgtcat aggttgactc
     6721 atcactatag cttgagctca ttcgtatcaa gtgctttggc ttgtcagctg aatcctctgt
     6781 ggcaatgaag gtatcaaatc ccaatttgtt gtaaacgatt tttcgagagt aattgttggc
     6841 gctcgcaagg tgcaaaacaa tcctatcctt aggcgaaaag gcattactaa tggcaggcga
     6901 aaacttcaac ttaggaaaga catcagaata caaaatcgaa actgttggat tgaggttata
     6961 ttttggtagg ccaaataggc tttgaaactc catattagct gtaccgccgc catagccatc
     7021 agaggtcatt aggccactcg ttgtggtttc catgatatga tggatctctg caataggatc
     7081 cttggccaat tgaaccccag aaatcctagc tgggtcagca aagctctcac tcagtatata
     7141 aatcactgtt tgatcagaaa tacgctgatg cctttgctta ttgatatcag cagctctagc
     7201 ttgatatttc tgataaatct tttgcatagc gctcttgcta tagcctgaag gctgattaat
     7261 ggtgctggtg gtaacctgct tgaaccaaac aaagctcaag gattgaaacc ttgcattggt
     7321 tgtaagacca taccagtcaa tatcaaagac attgtagact gatgacagaa ctggaatacc
     7381 ttttttgatt tcaccatctt tattttggct aaatacaaaa aggatagagg caaataccaa
     7441 aaggatagag cctattgaca tcagtctaag ataaagcgct gataggatct tttctctaaa
     7501 gtatctttta tacaaaacat agatcagcag acccgacaag actagtatca aaataatact
     7561 aatgatttga gtcagactaa tgtaattcaa gaaaaactta atctctttga tccatttcaa
     7621 atctgaaaac aataaaggct cacttcgctg cttgtatttt tcaatattaa caatactgat
     7681 taaagctccg atcaccgtat tgacaaataa agcaatgata tagttgttaa tgagcaaaaa
     7741 caccagcaca aaaaagaggg tcaagacaag cacctgaaac agggttgcac ctggaataat
     7801 cactgcccca tgaaaatcac catatgctgt gatcccagcc tgaataaagt aattaaagat
     7861 gatccctaaa aataagctgg tcactagagc taatctaaga ccccatcgct tgctcaaaac
     7921 ctcgataaag gctgtgacga tgaggtaata aaccacaaac gtcagcatat aagagcaaaa
     7981 gctatactta aagagattca ggctaacaag gtttgactga ctatctaaag gccaataatc
     8041 attttgctta atcacagtct taaataaaga gctgttcagc gttaagactg aaaaagcctg
     8101 actaagtaaa atgacttgga ttcctctgtt tgattggtag tccttcttaa acaggtattt
     8161 ttttaagaga acccctaaaa taagcaggct gactaaagct gccagactga gtagcatttc
     8221 ctgaatcgta cgattactga tggtaaacct gctgttgttt ttattgatgg ctaaggtgat
     8281 atagctatta gcaacagcat agtagctact gacagctaca gaaacaataa gcagctttga
     8341 ggaagcatgc ttgatcagca aacatgccat tccagctatt aacactaaga caagccacga
     8401 accataagct cccttattta acgtgttttt gcttaccgca aaaatagata aataaagaga
     8461 tgaaaggcta aacaatatca tatcaagcat ttctagatca actaactggc gagcttttga
     8521 aattatcttc gttattataa tggtcacacc ctttcctaac tgctaaaagc tagacattac
     8581 tctctgactc agaagcgatt acctctgtta ctaattgacg aacagtgacc tcccaggtaa
     8641 agcctgaaag cacctgctga tgaatggctt cttgcaggtc acaccgtttt tctttgtgct
     8701 caatcaaatg atccaactgc cttttaatat cagagactgt atcatcaatg atgattccct
     8761 gtgacgggct cgttatcact tccttgacac cacctctatc tgttgctaat acagcacatt
     8821 tcaacatacc tgcctctaat acagctgtcg gaagcccttc agcatagatg gacggattaa
     8881 caaaaatatc agattgagac agcaaagaca tggtctcagc aaaattcagc ttgcctgtaa
     8941 agatgatgga ctgatcctct ttatagctat ctcttagtga agcaagcaag ggaccatctc
     9001 cagcaaccac caagacagcc ctgtccttat atgtcagctg ctcaaaagcc tccagcagca
     9061 aaagaatccc cttttccttg atcactcgac ctgcaaaggt aataatgacc ttatcctgca
     9121 aagctggtaa ataagccttt gacttaaaga cctcataaag atcagaatca actgaattgt
     9181 agatgacgcc tttggctttt attccaaagg tcttgagcca tgccatactg cgcttagaca
     9241 ccgcataaaa gtcgggctga taggctttga caaaaaaggt aattacatgc tcatagactt
     9301 tagcaaacaa gtctagtagc tggtgacctt taacattttc gcccacctga acatagccac
     9361 caccatgctc gatcacaata ctagggatgg cttttctttt ggctagcttc aagcccatga
     9421 ggcttgtcaa ataaaatcgt gtattgcaga tcacaaagtc aatacgttct tccatcagct
     9481 ccgccagcat gctatgatac agatcattct tatctaaaat cggatagcgc tgcttaaata
     9541 gctgctttga aggaaatcgg taataagtaa tggcttgatc tctttcaata gggctcagct
     9601 ggtggctgtt gctggttaca atgatgatac ggtagcctag gctcactaat tgttgcgcta
     9661 ttttttctgt ataccgctct actcctccta gatgagggct tgtaaagccg ctaaaaatgg
     9721 ctattgtttt caaagctttt cccttcttat gtataatatt gcagcattgt tcgagtaatc
     9781 atacctagga tcaatagcaa cgagccaata agaacctgtt tattacttaa taggccttgg
     9841 gccttttcaa ggtatttgtt attagaggcc agcaagacca acactaaagg gatcacaccc
     9901 aaaaagtacc tatcttgaac ccctagcaca ttaaggtctc caactggcgt aaaggtcaaa
     9961 taaaggctaa aggtaatacc gcctattatt cctaaagaca tcaatcccat accaaagcga
    10021 gataaggtcg gcagctgaag cttgttggca ttagtgatga caacagcaaa ataataaacc
    10081 atactaattg gcatgagctc taccataccg tatgataaag ggccaaacat gtaaatccct
    10141 gaaggattaa ggatatgagc caacgtgtgt cttagcagca taaagccata tactataggg
    10201 ttccttaaca cagtcagtag ctgctcttta gcattgacct tctggagaaa gtcagccata
    10261 tccacctgag gtgacttgat ttgaccatat acctttaacc aaaaaacagt cacaaccagc
    10321 accgtcagaa ttgacaacag ctttagcaga aacgtgcgag aggcttttgc tccaaattga
    10381 cgtgaaggga taaaaagcag caacaaaatc aataaaatat aaggcagctt agtaaaggta
    10441 atgattgagc acagcagggt ataccaaaag agcttggata agggaatctt ttcagttgta
    10501 gccatctgaa caaataaaga aatcgtcaga ataatcaatc caatagagac acaatcctga
    10561 ttataagaac cagcaagata gatattcatc ggaaggagac ttcctacagc aagcagctgc
    10621 ttgcctgctg tcagcaatcg taaggcaaca aaaaccaaga tggcataggc aagaacatta
    10681 caaagcctac ctaaaaggta agataagccc atggtcaagc ctaagctcct tccaataaat
    10741 aagcctatta cctgtggtat gtaggcaaag ttataatagc catttgttga gcgaatttcc
    10801 ttaaatgaaa tagcctcatc tgtatggtct ctgctccaca gctgaaagcg taagggcttg
    10861 ccattgttgt ggtccataag attaatgtca tcagtcacca gcagctttga gtcatcattg
    10921 gttaaattaa gatttccctc agataagtat aaggctcttg caaagtgaac cctctcatca
    10981 ggaatatcat tgatcggtga gatgaaggca gagacagaac ccataaccac aataataagc
    11041 actgtcgcat attccatatt tgaaggtaaa aagataatca aaagcgcagc aattgcaact
    11101 aatattgcta aaaatttaat gggtaaatcc gttgattgcg tatataaaag cagcaacaca
    11161 agaaaggcac caagtaaaac aagcaaagcc ttactcgcct tttgcaattt gtcaaataag
    11221 gtatctaaca tatcctattt ccttttttcc ataatgtaca agccatatga caatagcagc
    11281 caaatcatca ttgaaattat aaaaccatag gtaactccaa tcaccccaaa gcttctagcc
    11341 aaagaaccag tgatggctag tgaggagata aaggatacaa cataaggtat cacaagcaag
    11401 tgctgctttc tgataatggt aatcaaatta tcaatataag tggcaaaggt gctgataatc
    11461 cctccaaaaa taagaagcat aaaatcaagc tggtaatgcc ttaaatcaat accataaaca
    11521 agcgatagca ccggcagccc cacaaaatag ctagcaagca agatagctag gcttgctaat
    11581 agcagcacta gactgagacg acgctctaat tgtgcaaagc tcttctcgtc ctcttttgaa
    11641 tggtaaatgg ccagctgagt gatcataggc cttaaaaaca agaaaatcag gttaatcata
    11701 aaaataggca taaacaaaat attaaattct gtttgaacac cggctgggat cagctgcttt
    11761 gagtaaagct gctccaaaac aaacttgggc tggttgtaga tataaatgag taaaaaacca
    11821 tttaaaaaga ggggaaagct ctccttcaat agccctaaga tgctttgagc atcaatacga
    11881 cgctcaaggc tcgtaaagga aactgaaggg gttatgtcaa atagcacaat acaagccact
    11941 gaaataagac atatcacgat caaagacagg actagctgct tggtcagaac cagacagagc
    12001 gtaaagccaa gaatcaccag catatttcga taaaacaagg atttgccggc aatatctaag
    12061 cgctctcttt gttgaaacat tccttgaaac acatcagaaa tggcatctgt gcaacgatac
    12121 aagcaaatca accaaatcac tagcccctta aacccactat agctccccaa ataaatatag
    12181 agcactgaaa tggctatcat caagaaacag gtgactagtc ttgtataaaa atagtctttg
    12241 aagcggtact tgtgtaatat atccgttgat tggaaatttc taatctgaaa taagccaata
    12301 gtaatcagct gatttccaat agcataggca aagctaaagg tatctgaagc tgatttagat
    12361 aagacccgag acacaatcat cagtaaaatc actgatatta gtgctgtcga gctggttccc
    12421 aacacattcc aaataaaaat cgactgatcc gattgaatcc tactgctggt tttcatcttc
    12481 ttcctgcttt tccttctcat taagggctaa atactgaatc atttttttaa gcttaatctc
    12541 tgtccgagac aatttttgag tgataaaaaa ttggttgatg atgagtaaaa aaatgattga
    12601 tagaaaaaca aaatttgccg gcgattcaaa gcctagcagc cttgaaaaat aaaccgcagc
    12661 atttggaaac agtgacagca aaagcactat taaagagaaa aagagccaaa aaaagctatc
    12721 ttcaattaaa attttggatc tgcgaatgct atctagtata aacatggctg tcaataatgc
    12781 aacaatgatc aaaatcagct gtaacccaat aaacatcctc ttacctcttt ctaaagtttt
    12841 gaattaaaat aatcgaaata aacatgtgaa ccatgtattt aatagatcta gaaagagtga
    12901 ggtagctttg accagccagc ctatcattca tttgcacctg aacctcactc accctatagc
    12961 cttgtcgaat aagataagag atcgtatcag gctctggagt atagttaata ttagttgcaa
    13021 aaatcctgat cagctcctga ttaaacattc tcataccaga ggtcggatcg gtaatacgct
    13081 ttcctgtggt tagcttgata aaaaagctaa taaggctatt gcctatcatt ctcaaggatc
    13141 tattcttttc agcactgaca aaccttgatc caatgacaca atcagcacca gcattaattg
    13201 aatcgctcaa agcctcaata tactctggca agtgttgacc atctgcatcg aactggagtg
    13261 ctttagcata tcccttttta aaggcatatt taaagcccgt ctgaatagca ccagataagc
    13321 caagattttc cggcaaatca atgatattgt aatggttatg atgacagatc tctgatgtcc
    13381 gatccgaaga gccatcattg ataatcacat aatcatattg aggaaaatgt cttttgatat
    13441 tttccactac tttttcaatc gactcctctt cgttatatgc tggaatcatt accaataagt
    13501 cttttttcat atcgtcaaat attctctcta ttcattcgtc taaacgcgtc tttttagcaa
    13561 tcgctttatg atataacgga tagccttagc tggcccaatc acaatatatt ttaaggctcc
    13621 ttttatacct cccatatagt caaaatcgac ataggtatgt ggcacactgc cttcacgcag
    13681 gtttaagagc ttattatcaa taaatggtgt caatagcttt tcatttcttg aaattctaaa
    13741 atcatagtgt ctgtcccaag caatataaat taagagacgt tcaatggcat gcaggatcga
    13801 attttgagac agaggctctg ctggaatatc agcctcactt aggtctaagt caaacaaggg
    13861 ctttaaggca tcgtatttaa accaaacaaa ggtgccatag ctcatgacaa aggtatccat
    13921 cgtctgaaaa tcaatgcgtt ttgtaagccc cattgcctgc caaagctgat tcatttcagg
    13981 ggcaataagg tgctcattcc aagcgtcaac aattttatta aaacggaaaa aacttggaat
    14041 atctgctatc acaataccga tagcatcagc agccagtgct gttaggattt gatccgccgg
    14101 cttcaccatc atatcaatca attcagtgcg ccaggattgg cccgcccaaa aatctgcttc
    14161 ctttgatttt ttggtatgaa aatgcccaat ataatcatat tgagacaatc gttcctttaa
    14221 ggtcagcatt ggcaagacat ctcgaccgat atttcctgtc accaatatgt cagcacttgc
    14281 cccgctttct cgtagaattt ctttaatctc agccttttta gccttgctat cggtcgttat
    14341 gagcaagtca taatcaaaat gaaaatgact aaatgcttct aaaaactctg acaataaatc
    14401 aacataaaaa acatgaagat gaacagcaat tttcttgctt tgatcaatgc ttatcggctg
    14461 ctctggcagg tatttatgtg ccagaagata cttagcatct ggtggatgga cctgcgacat
    14521 atgatccaca atcaagctgg cagggtatgt cgttttttgg tcaataaaat ccaaaaggta
    14581 aggagcaatg tgctggttag cgtcaatagc cttaaccttg ataaagggca catggtgctt
    14641 taagatggct gtcggattgt aataagagaa atccgcatgc agcatagagg acgagtcctc
    14701 cttggtcgta tcaaataccg tcttgtatcg aaagccagcc tccacaaaga cagtggttat
    14761 tctggtttca taattgtgga tcacatcttg aacgtctgtt agctcaacga tattttccca
    14821 aaactgccta aattccttac tatgaacgag ggattttttg aagctgataa aatagctctg
    14881 aatatgctct ttaaaggcct tggtcgctcg attgttggtc atgccccaga aatcaactgc
    14941 ttcatctgct tcatatttga gataataagg cttcatatcc caaagcggac caaagcaggt
    15001 atcgttcata atcgtgattg agtcaaagtc aacaaggtgc tcacagccta aggccttcat
    15061 accatcatgc caagctgcaa aatcatagcc tttattgtgt cgttgaataa actgatccat
    15121 caaatgccgc tgttcaagct gctcaaggtc ctcttgatgg atatcactat ttgaaataaa
    15181 gacaatcttt gaaaacaagg ctctcatctg ttcgagctgg taataaacat gatcgcttac
    15241 cttatgatat ttattgaaat gcacatacaa taatagacgc ttcatttttt cctcctaaaa
    15301 agctcaagca gctttgatag gtacctccaa cgacgtgagg taaccacaca attgtattga
    15361 tgggttagcg cttcaacctc ttgcctttga tgatcaagct gctgctgtag ctgatctatc
    15421 ttctctgcct gtagagcctc ctgatctgca agcgtctgtc gtaattgatg aatggtatga
    15481 cttaattgat gaatccgaat ttcattttta gcgtcctgct ttagtaatgc ttttgcaata
    15541 gcttccatat tggctgtagg gtatttagac aaataggaca gctgggtctc caacaagcct
    15601 tgaatacggc ccagcatttt ttcctctgct gccggccttg aatctgaatt atccgtcatt
    15661 cgataaacag tggtcgaatc cttcaaatag gctagagagg ttgactgaaa cagctctaat
    15721 tgtatgtcaa aagtgtcgtc tgacgtctcc aaatcaatgc gttgattaac tgccctcatc
    15781 agatcagcct ccaccagcca ggttgatgac atggtcattc cttttaaagc aagcattttc
    15841 tcgtaggtgt ctgttaaggg agtaaagcca ctttcaaagg cattgctctg aataagcttg
    15901 ccgtcagtat ctacaaaatc aaagtcagta ttagaccatt ttgaatctgg tgagctatcc
    15961 agcaaatcaa cctgcttttg tagcttgaga gtatcagtcc aatagtcatc accatcacat
    16021 ctggcaatat actgtccctt tgcctccaaa caagccttga cccaggttct tgcaatccca
    16081 agatttacct cattaacgat gagtcgtata cgatctggaa agctggcttg atagtccatg
    16141 aggatctgtc tggaatagtc tgttgaagcg tcgtcaatga caataatttc aacatcaaag
    16201 ctggtctgtt gggctaaaaa gctgtctaag gcctctgaaa tccaaggccc cttattataa
    16261 ttggtgcaaa taatagaaac ttttttcata ggatgctttc taatgacaat tattgattaa
    16321 tgagccagct accatttctt tgatataagc cactggcaga gtccaaagca gacaggtcat
    16381 ctggagcaat atcgtttcgt tgaagcacga ctaatgggga atgattagct gttaaaaaga
    16441 gcagcatttg cccgttttga tcgcgaacag tcacctcaag ctttaatttg atatcattta
    16501 ggtgtgagag ctgacactgg taggatatgt tcttatgacc aggaccactt gtcggttgat
    16561 cctgtgaatt gtcattatat acccaaatat tgcggtcaat atcagtcaac gaaaaggcaa
    16621 cataggtagg ctcgtccttt aagacatgat aggaaatctc aaaggaaatg ggctcatctg
    16681 gactaaggct tggcttagag gtcaacctca cctctaactg gcttgccaaa tcagacacag
    16741 gctcagcagc agctccttgc tcagcatttt tcaattcagt attatcaaca ctgtattggt
    16801 tagcgacatc aaagggttcg ccgtaagcct tgacaaggcc attttcgatg aggactgcgc
    16861 gattgcagta ttttttgaca gcccccatat catgggtcac tagtatagta gtcttgccgc
    16921 tctccttgcg ctccatgaag tagtcattgc attttcgttg aaaggcctca tcaccaacag
    16981 ctaacacctc atcaagaatc agcacatctc cctgtgcctt gatagcgaca gaaaaagcaa
    17041 gacgaacctg catgcctgag gaataatttt ttaatttttg attcatgaaa tcatgcagct
    17101 cagcaaagtc aacgatatca tcatacatat catcaacctc ttctgtggta aagcccagca
    17161 ttgcgccatt catgtagaca ttttcacgcc cagtcaactc aggattaaag ccaacaccaa
    17221 gctcgatgaa ggacaccatt ttcccctcaa ctgtgacctg tcctttttct ggaacataaa
    17281 tttgagaaat aatttttaat aaggttgatt ttccagagcc atttcgtcca acgatgccaa
    17341 aaaaatcccc cttatacacg tcaaagctaa tatcccttag cacatgctgc tcggtatagc
    17401 ccttaatgcc tttaaaacgg ttaacaagag cagtacgaaa gctcttggtt gcctctgttg
    17461 gcagcttaaa ggacttactg acatgatcaa ctgttactgc aatttcttta ttagccatta
    17521 gataatctcc gcaaacttct tagcattttt attaaacact gctaccccaa gtgctaatag
    17581 gacaaatgga atgaggtaag gaatgatgat atagcaccaa tttgtcgaca tttgccaaat
    17641 ggtcacatta gctctgtcaa tcagcagata ccgcaaatct tgaataatct gtgctaaagg
    17701 attaagcatc aaaatcttgg cagcaagagg gtgtcggtca aacacaaagg taatcgggta
    17761 gatgatggga gtcacataca tacctgcctg caatagaacc tcccaaacct gagccaaatc
    17821 acgataataa acaaagacgg tagaaagcat caaggccaca ccaactgtaa gaacagccag
    17881 ctcaacaaag agtggtaagg ccagataagc gtgaggagat aaagtaactc cattgatagc
    17941 tgcaaaaacc aaaaccacta ataggttgat tgaaaagtta atcaatgctc ctaaaactgc
    18001 tgaaaaaacg atagtatgct ttgaaaaatt caattttcta agcaggtctc ctcgcgatac
    18061 aatagagacc attcccatac tggttgcttc tgagaaaaag gaccaaatca cattggcaag
    18121 taaaagagca accggaaaat gaggaacgtc accaccagtt cgcaaaaacc tgataaacac
    18181 caaatacatg atggtaaaca tcatcaaagg ctttaagata gaccacaaat aaccaatagc
    18241 actgccctga taccttagtt taaagtctgt tttaacaagc tctttcaaaa gaatacgatt
    18301 ctttttactc aataattcca ttattctttt ctcctatagc caaatttggt catgatcaat
    18361 gccataaaaa caagggtatg aaaggcacga tttttccgaa agccatacgc tttgaaatca
    18421 gacagacgct gatagaaagg cctatccaaa agccctacgt aagcctcaat caatcttctg
    18481 tcagccggat ttagctgcaa gtctagcaat tgccttgctt gatgttgact agaaacaata
    18541 agccaccaat acttctctat gagcttatgg ggcttacgcc actgcttcag tcgcttagac
    18601 caggttcttg cccctaaaac attagcatca tgctgacgat agagctctgt tgccacatct
    18661 agatacacaa gctctccctg cgctgctgca atcaaggcta aataccaatc atgcatcacc
    18721 acatgctcac agctcaccca ctgctctgcc agcgcgtgat taatcatcat agtgccgcct
    18781 gtgactgtgt tttcagtcaa ctcctggact agctgagtat tagcatgatg tgattgtgtt
    18841 tggatcatac tctcatgacg tacttctaag tcttgattga ccacctttag gtctgtgtag
    18901 actagtaagg gctcgcttat cttgtgcttt tgcgcttctg ccagagtaag ctctaattta
    18961 ttgtctaacc acacatcgtc ttggtcactg aaaaaataaa tatctgcctt ttcatatgtt
    19021 aaaagggtgt gaaagcttcg aatcacaccg aggttttcct gcacatcagc attaatcaag
    19081 caaattctcg gatccttttt agcaaaagcc tgaatgatgg caagcgtttt atcagtagag
    19141 ccatcatctc tgactaataa ggtccaatcc tgcaccgtct gcctttgaat gctttgtatt
    19201 tgctctgcta aaaaccgcgc cccgttgtag gtagacatta aaatattaat cttcatctaa
    19261 aaataaggcc tcatactctc ctacaatttt ctcccaggta tattctttgg caatgatttg
    19321 cttagctctt tctcccaaat cagcaaacga ttccttttga tcaaccctgt taatcagtcc
    19381 agtaaggctg cccttttctt ttgtccaata aagggctgct gttttagcaa ctgattgatt
    19441 aaaggtcact cccaaaacca aattaagctg ggtatgggct agggcctcca aaagacctgg
    19501 attggtacct ccaacctcat gcccatgaat ataagcaaaa gcatgctcac gaatataagc
    19561 taaaagctgc ttatcatact gtgttccaac aaattttaca cgcgcgtcct tatcacagcc
    19621 agttgcacta accagccgct caaaataagg atttttgtca tggttgcaaa taataaccaa
    19681 atcccgctga gtagatgatg ccataaactc tctaatggct gtttcatagt tgttttcagg
    19741 aacaaagcgc cccaaaatca aatagtattg gttttctgtt atctcaaatg tttgaaagta
    19801 agttctgact ttttcatctg atgtagacaa acaagaccgc cctatttctg tcccataggc
    19861 aataaaagtc gtttttgccc aaggataaga ctttttgatg taggcttcaa tgccaatatt
    19921 atctgagatg accaaatcag catgctttgt catttgcttt tcggcgtatt tcaggtattg
    19981 ctgaacaggc ttagaccatt ttgaacgctt ccattccagc ccatcaggat taatcaacaa
    20041 acgcccacca cgctggtgaa tctgctttgc aaagggggca ataaagcctc caatggtatt
    20101 gcctagaaca taaaaaatag gcttttgaat atgataccta tcaatataag ctaaagcgtg
    20161 actaatagcc atcatatcat aagcaatcac tctagctgga ccgagcttag gaggattgat
    20221 ataaaaacaa tctgctccct tgtacacaaa atgctccttg tgcttgctat cgctcaagca
    20281 ggcaatatga taggtaatgc ttttgttggt ctgattagtg actaattctt caacaaaggt
    20341 ctcaaaacca ccatactttg ctggtaaacc gcgacttccg atgatgaaaa catcctgcat
    20401 agcacactgc cccattctaa aatataatta gtagtattat accatataaa caggtcttat
    20461 gcgacataaa atccatgaaa agagagccaa tctcctagat cagctcttta gtgctatcgc
    20521 ttattcattg ctgttgcttg taaaaagcct ccagggcttc ttgccaggta ggaatcacaa
    20581 aaccagttgc cttagcctta tcaagattca tggttgagtt aaagggtctt ttggctttag
    20641 caggaaaagc cgatgaatcc acaggcacaa cctcgacagc tgtctctttt aagatttctc
    20701 tagcaaaatc ataccaagtg gtgtcttctt tagcatcatt tgacaaatga taatagccat
    20761 aaggcttgcg attgtctgct agatgacaca taaactcagc caaggtcctc gtccaggttg
    20821 gacgcccatg ctgatcattg acgactgtca agcgagagtg ggtcttagca aggttttgca
    20881 tggtaaacac aaaattcttg ccataatgac caaacaccca tgcggtacga ataatgtaaa
    20941 attgcttggt atatcgctca acagccagct cacctaagcg cttagcacga ccgtatgctg
    21001 tttgaggatc aggagtatct gtttctagcc attcctgacc agctggcttt tgaccatcaa
    21061 aaacgtaatc cgttgaaata taaaccaagg tcgccccgta gcgctcacaa gccttggcaa
    21121 tatgctcagt accagctaca ttgatagctt cattcagtgc ttttccttct tcttcagcag
    21181 catcaactgc tgtgtaggct gcacagtgat acactaagct aggcttgacc tgagcaaaaa
    21241 cctcctctac tttagtcgcg ttggtaatat ccatttcagc aacatcaaca gcaacataat
    21301 cgacgcttcg ttcgtctaaa agataacgaa gctctgttcc taattgacca ttacttcctg
    21361 taattaaaat catcttttct cctttgtaaa ggtcttattt ctttgagcta atcacgcagc
    21421 tcactcccat ctaatcctaa gagaggcttt tttgatcagc tgaccctagc aagacctttg
    21481 ttgtggtatc gtatcagcct tgctttttat ctagctaccg aatacctagg gcaattctcg
    21541 catagcggct catcttttca acgctccaaa cagggtacca gaccaacttt acctcaacct
    21601 tggtcacctc tggaacatct ctcatcgcat catgaatatg atcagtcaac aaatccgcca
    21661 aaggacagcc cattgtggtc aaggtcatgt caatctcggt atgaccattg tcatcaaaac
    21721 gaatctcata gaccaagcct agattcacaa tatcaatacc tagctccgga tcaataaccg
    21781 ttcccaaagc ttcaagaatc cgatccttga tagctgcaac ctgctcttct gtgtatttta
    21841 atgtttcagt catagctatt cctttcactt ttttcgaaga cctgatatga tgccaagtca
    21901 aaaaccagcc caaagaccag cgcattcagc atacctatga tgccctaagc tgactaacat
    21961 tgatagcctc tttttagtca cccttacatt aacactagtc tttagctact ggctagcaaa
    22021 ggtaatctca taaaccagta actaggcttg gagtcgttga ccataggcca ctcaccgtca
    22081 aggagagata acgcatttcg ggctcgtctc ctatttttag ctcgccgtta aaaaggtcca
    22141 ccggaccttt ttaatcctca atgaagtctc tgagctgctt gctgcggctt gggtggcgga
    22201 gcttacgcaa agccttagcc tcaatttgac gaatccgttc acgagtgaca ttgaagacct
    22261 tcccaacgtc ctctaatgta cgcattttcc catcatcaag cccaaagcgc aggcgaagaa
    22321 cattttcctc acgatctgtc agcgtatcaa gcacttcgtc taattgctca cgaagaacca
    22381 cacgagttgt gtaatcaaca ggattttcaa tcacttcatc ttcaataaaa tcacctaaat
    22441 gactgtcatc ctcttcaccg attggtgttt caagagacac tggctcctga gcgattttca
    22501 gaatttcacg caccttatca ggggtcatct ccatacgctc tgcgatctgc tctggagtag
    22561 gatcctgccc caattcttga aggaggttgc gctgctcacg cactagttta ttaatggttt
    22621 ccaccatatg cacaggaatc cgaatggtac gtgcctgatc tgcaatagca cgagtaatgg
    22681 cctgacgaat ccaccaggtc gcataggtcg aaaacttgaa gcccttagaa taatcaaact
    22741 tgtcaacagc cttcattaag cccatgttac cttcttgaat caaatcaaga aattgcatgc
    22801 cacgccctac ataacgcttt gcaatcgaca ccaccaaacg cagattggcc tcagcaagac
    22861 gctgcttagc ctccatatca ccagcggcta ctgcaaccgc taaaaccttt tcctcatcac
    22921 ttgtcagcag cggcaccaca ccgatctcct tgagatacat gcgcacagga tcgttgacct
    22981 tggctgaatt acttccgata agctcctcgt ctgtcagctc ctctggctta ggctcttcaa
    23041 cgacgtattt agatgaggga tttccttcct tatctgtaat ggaaatgcca ccatctgtca
    23101 aacgctcaag caaatcatca atttggtcag catctaaggt aaatggaatc acgagttttt
    23161 ctgtgacctc atcatcagta gctgttcctt cctttttatg atgacgaata aactccgcaa
    23221 tttgaacgtt aaaggttgta atttcttttt cttttgccat attttcctct attccatttt
    23281 tcttttttca gcaatgaaac gctctaaagc ctctagagcc atctggtggt cacccttact
    23341 gctagattcc ctaatctgct ttccttgcct atgcagctct ctttgcttta gcaatgtcat
    23401 ttgccttgat aaaatatcct caatctcacc gctagctatc tcatcaggaa gattttcctc
    23461 taaaacccgg taataggctt ggttaacctc ttcagacagt tgcgataggt cataggaggt
    23521 aatctgccct gtggccttta gctgctcata cagcgtctga agggctggtg tatcaaaata
    23581 aaaatccggc cgatgacgaa attcattgag caaatagtcg tgatgaagca ggcgatgcag
    23641 gaggtgactt tctgttttag ccaaggctgt catgcttttg ttaatcggta aggtcaccag
    23701 agatgccttt ggttgactag cctgtccttg ttgtaagctt tgcctatctt gtagccttaa
    23761 agcatttacc gattgctcca cctgaaaata atcaaaatcc ggcagcaaat cagccacctt
    23821 attaatatac gaattttgtg cggtgattga gggtgcttga gcaataatct gtgatatatg
    23881 ctccacataa gcaatctgcg attgcaggtt atccatattt tcaggcttca ggtgatcaat
    23941 caaaaactca acactgctaa tgcgcgagtg ctggagcaat tctgctagag cctctggtga
    24001 atgctgctga acaaattcat cgggatccat tctatttggt attttcacga tctccacttg
    24061 aaaatctgcc agcagctcaa gagacttggc aatagcattt tgcccggcgt cgtcaccatc
    24121 ataagtcaat acaacctttt gtgtcagctg cttgaggtgc ctaacatgct ctggcgtcaa
    24181 ggctgtcccc atagaggcaa cagtattacc atagcctgcc cggtaggctg caataacgtc
    24241 cataaagcct tccatcaaaa agacctcatg agtcttagcg attatcggct tggccttatc
    24301 aaggtggtaa agctcatagg acttgttaaa taggaccgta gcccttgaat ttttatactt
    24361 ggcctgctgc ttttctatat cctctcttgc ccagatacgt cctgaaaaag caatcatatt
    24421 gcccttatca tcacataagg gaaacatgat tcgatgacga aaggcatcat aaatagcatt
    24481 tgattgttca gaaacatgaa acaagcctga ggctgttaat tgcgcctcag tatacttttt
    24541 tgacaaggct tgataaaggt agtccatctc gttaggcgcc aagccaatcc gaaaatactc
    24601 tattagctga tcatcaagcc ctctttgata aagatactcc ttggctcttt ggccaatctt
    24661 tgtcgtcatc aaaaccgcat ggtaaaactt agcagcatct tcatgaagat caattaaagc
    24721 ctgatgaggg tgctgctttt gactcaaact agtctgactt ggagcaacag taactgccat
    24781 accagcctta tcagccacaa tctgaacact ttctaaaaaa ggaacctgcc gatattcctc
    24841 aataaactta aaaacatccc ccgacttacc gcagccaaag cagtgaaaga actgtctatc
    24901 ttcgatgaca ttaaaagagg gtgttttttc tttatgaaag ggacacaatc caaggtagtg
    24961 ccgaccagcc cgcgatagat ggacaacttc tccaataaca tcaacaatat tgacattatg
    25021 cttgatctga gaaatcatct ctttgtcaat agccaaaccg tcacctcccc acaaaaagcc
    25081 cattgtaaat ttacatttca ttataccatt gaaaatgagc tttgtaaatt gtaaaagcac
    25141 aatccttcat catctaaagc ccgctacatc aagcaataag ctatgctaaa gtattgacgt
    25201 ctcttatgat cactagcttg actagcagta cagcattaag tagctcatca gtccttgata
    25261 agctcttcta ttagcctttt tgacctattt gtgctatgat aagattatct gaaaaaaggg
    25321 gagtcaatca tgctcaaaga attaaaagca tttttattta gagggaatat tatcgaccta
    25381 gcagttgcgg tgattgttgg gagcgccttt agcgctattg tcacatcatt tgtcaacgac
    25441 attatcacac cgctgatcct aaacccagcc ttgaaagctg caaatgtgga aaacattgct
    25501 cagctcgcct ggaatggcat caaatatggc agctttctca gtgctattat caacttttta
    25561 attgttggta ccagcctttt ctttgtggtt aaggtcgctc aaaaagcaat gcctaaaaag
    25621 ggagaggaag agcccgctaa gcccaaaaca ccaactcagg aagaattatt acttgacata
    25681 cgtgatttgt tagccaaaaa ataactcaaa gctcttacag cagctggacc tgtccggctg
    25741 ctttttgata tacaagcaca gagcacttag cgatcaaaag ataatagaac cggctctatt
    25801 tgctgtttta gcatatcatt gctattttta tcagcagcaa gctaaggtaa aaaaagacaa
    25861 actagtatcc tcatactggt ttgccttcaa actaaggcag cctacaaagg gccgcctttt
    25921 ttatgatgat tagaattttt tacgtttgcg agctgcttct gatttgcgtt tacgctttac
    25981 agaaggtttt tcgtagaatt cacgcttgcg tgattcttga agagtaccag ctttagtaac
    26041 agaacgtttg aaacgacgaa gagcatcatc aagcgattca ttcttacgta ctactgtttt
    26101 tgacatatgt ttcacctcct caagatattg taacattttc acgttctagc ttatcttaca
    26161 tgatttttcg gaaaaagtca atgatctttt cttgattttg aggtcattct taaaaaaata
    26221 ccttaaaatt tgctgctgca ttaggcatca cttggcaagg ctattctact gcatttcctg
    26281 ttaataatgc tgcttcttga ataaaggcct tgtatttgcc atccttgttt aattgcttga
    26341 tcaccttatt aatggtttgc cttaggtcat cactcccctt tggcatagct acagccttag
    26401 catctccatc acttgcctgc aatttaaatg gtgctaaagc caggtcttta tgttgagcta
    26461 aaaagcctgc agctactggt gcttccaaat caacagcctg cacctgccca gatttcaact
    26521 cattaatagc ctcacccatc acagttagag aaacacagtt ggctttatta agctgctcct
    26581 tgactaggcc ctcctcgatg ctgccttttt gaacagccac ctttttgcca actaagctat
    26641 ccttattagc ataatgcttg gcatctgacg ctttcaccaa aatagcattt tcagtttcat
    26701 agtaagcctc agaaaaatca tacactttgg cacgctcttt ggtgtaggac aaaccagaaa
    26761 tcgctatatc caccttacca gtttgcagac tggataagac attatcaaaa ttcatagcag
    26821 agagttcaag cttaacccct agttcatcag caatggcctg tgccagctca atgtctgctc
    26881 cgacaatagt atccttgccg tcaaccaagg ccttaaattc aaaaggagca tagtcagggc
    26941 taacagcaac caccagcttt cccttttcct ggatcctgtc ttgaaggctc gtcttgttag
    27001 cttggccaca agctgccaaa gcaaaaacag ataccatagc aagtgctcca actaataatc
    27061 gcttcatgtt catattataa ttattccttt tcttgttgat gaatcttatt atattgcatt
    27121 attattcaat ggtcaagttt ttattgaata tttttcaagc actgcgatag tctgcttaat
    27181 cctgcctgta gaacctgcgg ctgacagcaa tagccgattc tcacatgatt tgcttgatta
    27241 aagcgatttc ccggaacgac caaggtaccg taatcctcca gcagcctcaa agcaaaggct
    27301 tccatgtcct catctatatc tagcctaaca aaggccgttg agacctcatt cggtctatgg
    27361 taggaggccc tggcttcacc tgttatccag tcctctaaga tagcaaggtt agtcctgata
    27421 atggcttgat tgcgctgcaa tagcttgtca gcatgcttca aggctagcga agccaccata
    27481 tcatcaaaaa cacctgcaca gatcattgtg taatctcgat ataacctaag ctgatcacag
    27541 atggtctcag aagcggctac ccagccaact cgaatgcccg gaatcgaaaa ggtttttgac
    27601 atgctattaa cagtaatccc cttatcatac aaatctgcca ccgctaaaag atgatcagag
    27661 gtaaaggaat gataaacctc atcacttagc aggtaaatat catgctctct agcaatattg
    27721 atgagctcct ctaaataagg cttggtcata taggcacctg ttgggttgtt ggcattgttg
    27781 atcatgatca tttttgtgtt gggacgaatc atggcaccta gctcattaag gtctggcagc
    27841 caagcctgct cctctctgat ctgccaataa tcaacctcca ctccaagaga agctggaata
    27901 tcatatagct gctgatagct aggatagtga gcaatcacat gatcacctgc ttcaagcagt
    27961 gcataaataa ccaaaaaatt ggcacctgtt gccccattgg tttgcaagat atttctagct
    28021 ttctgctgct gataaagccc tgccactgcc tgcttaaagt caggagagcc ttctatccag
    28081 ccatagtcta atggcttttg atgcagctgc tggtaaaagg cttgaggctg ctcctgtgtt
    28141 aagtcaaaga gctcctcaag cgttaatgaa gcaatagatg agccagcaat atcgtataca
    28201 gcacgttttt catgctgatt tagccactct tctacaccaa ataccggtag tttcataaga
    28261 tcaccttatt tcttgcgtaa tatttattac aatatcgcat aaaaatacaa ttgtcaaatc
    28321 aaaaactatc ctttttttga taagaatcat gtcctatcta acagttagtc ctgattggtc
    28381 tcgcatgaaa ggctactaaa tagagcaaaa atcacataaa aagactccca acccaccaat
    28441 cagcgggatt aggagcctga tagctcgtat caattcattg atttcagatc agagtgacta
    28501 tcatcactct actatgagcc aatgactagg ctaggcggac aacttctagc tgtgatccac
    28561 ccattaatac caagtatttt tcgatccttg caatcccgta ggattggctc agagcctcgg
    28621 catataggtc catttgctgc tgatagcgct gcttcagctc agctgactgc tgatagcgat
    28681 ctgtcttata gtcaaaaaga acaatacgat cctcaaaaag caggtagcca tcaataatac
    28741 cacgcactac gtactgctcc tgacttaggc tgtctttttt cagcatcgca aaaggagcct
    28801 cgcggtgtag gcgctggtga tgctcttgca ggagctgccc caattcagtt gtcgcaaaaa
    28861 aagaggttac cttttcaatg tcaagccttg ccttgacctc tgcgtcagct gagacaagct
    28921 gtaaggtctg ttcaatatca ccagcagtaa cctgatcaga cattggaata cgctgcatga
    28981 gctcatgcag gcttgagccg acctggctag gctcaacagc ctttttctta gaaaaatcag
    29041 gaagctcaaa ggtcttgggc ctatgataag gctgatctat gatatcaaca ccatcagtat
    29101 ccattagagg ctcataaagg gttttaagct gactgggggt tctcaccgtc ggcagctcaa
    29161 tggccgcctg atagcttgca ttgagctctg acaccttatc cagcatgtct aaggcacgcg
    29221 caatgtcctc tgtttgacgg ttatccttga gatcatctgc ttgcagcagc cctgagggcc
    29281 ttagctgacc aacagcttct ggtgttaagt cactgtcatc aacaaatcgc acatcaataa
    29341 acaagtcctc cttgctaaat gttgctgcta tcgctagtag ccagtcttga aagctcagca
    29401 atctttctcg actagctaag gctaagcgtc cttcggagct attgtcggct gttttttcct
    29461 gtaccttttc cttgctagcc ttaccaatga ggtatacctt tttttctgct cgcgtcatgg
    29521 ccacatacaa gagacgcatt tgctctgata aggtcgccaa gcgtagctgc tgcttattga
    29581 gctggtaagg aagagtttcc atcgtaacct tgagcgacgc caatttttct tctcttagaa
    29641 gctcctttac attggcgaca tatttgatac cgattccctc atctctattt agaatgattg
    29701 gcgcctgtag gtcagccatc gcaaagcgct tgtcgcaatt caaaatgaac acgtaatgaa
    29761 attcaagtcc ctttgattta tgaattgtca tgaggttaac agcatgctta ggcctttcga
    29821 cctcaacatc tgccaaatca ttttgcgtct ccagcacctt atcaatcatg ccaataaagc
    29881 gtgagagtcc cttgtagcct gattgctcaa attggtcagc ccgtatagca agggcgtaaa
    29941 ggtttgcctg agcctgctct gcctttggct ggcttgctac aaagtcaaag taaaagcgat
    30001 cgttaaaaat cttccaaatc agctcataaa gcgaatgaag ctttgcaaat tgacgccagt
    30061 ctctcaaggt cccatcaaaa tcagccagct ttgtcatcag ctcctgaccg atcagctctg
    30121 ggtgctcgcc ttgtcctctc aagctattgc taagcttgtc atagaaggct tgaggctgct
    30181 tttgtgagct gccttgcagt gagattcttg ccagctgatc ctcatcaaag gaaaacattg
    30241 gcgagcgcat taaggccact agggcataat cattcaaagg attgttgatg cttcttagcg
    30301 tatccagcat gaccatcacc tcaactgatt tgaggtaatt ttcttggcca ccatcagcaa
    30361 cgagaggaat gccatactga ttaaagacct gaaaaatagt gtcatttcgt gtgcgtgacg
    30421 aaacaagcag ggtaatatct tcaaaagcaa ccttctcctc gttatagagc ctgatgattt
    30481 ccttagccac taagatgacc tcacctgcgg agataccatc gttagctaag gcttcctcgg
    30541 tgccttcttg aacttgatcg gtgtcataga gcagcaattg ggctcgattg ttaggatatg
    30601 gctgtctttg tccctcactg cctgctacca gctggtgctt gtcatcatag gtaatctctc
    30661 ctaaagactc gtccataagg cggctaaaga cagcgttggt gacatttagg acctctgact
    30721 gactgcggaa attttccttt agtaaaatca gcttgccatg ctcgggattg ctttgataat
    30781 ccttaaactt ttgattgaag atttgaggat ctgcttgcct aaagcgatag atggattgct
    30841 tgatatcccc aaccataaaa cgattatggc cattagacag cagctctaat aggcgctcct
    30901 gcatgtgatt gttatcttgg tattcatcaa ccatgacctc atgataatga ccttggtaag
    30961 cttggcgaat atctggagcc tgttgtaaaa tctcaatggc aaaatgagct atatctgaaa
    31021 attcaaaggc attttcttgc atttttgcag ccaaataagc ctctgaaaag ctgatcacaa
    31081 aggcttgcag cacctccaaa agtggtaagc tctcctgttg ataagcaagg atagtctcca
    31141 agtgcctaaa tcttaccagc tgctcctgta gcgatttgaa aatagggtat ttgtgaccgg
    31201 ctacagttat atcagctcct gaaggaagta aagctgttag ctcctgtgct agctgaccta
    31261 gtcgcgcttt accgtaaagg ctgtcaaaat gcaaagccca ctcatataag ctgtcaatca
    31321 ttttgaggtg cttagtgtat ttggcagtta gcttgccagc cttggttgtt tgagcgtaac
    31381 cctccatgtc tgtgaggtct cgcagctgat cagcagtgtc ctgcatacag gctaagagag
    31441 catctacagc ttggtctgga atatctgtaa agctggtata ggtcttagac cctcgtaaaa
    31501 agacctctgc caaccaactg ctaggattgg cagttgattg actgaaggca taaatgctat
    31561 caacaatctc tctaaaggct gagctatcct tacgacgtcc agaaaaattc tgcaccagct
    31621 gtataaaggc tttattgtca gtctgcgaca tatagtcttc aaaaacctga cgaaagacct
    31681 cgcgctttaa aatgtcctgc tctgccttat cctgtatgat acgaaaatgc ggtgaaatcc
    31741 ctaaaacata accatgctgg tgaaccaatt tctgagcaaa ggcatccatc gtaccaatat
    31801 cagcctgtga taaagcctgc aattggtcat taaggtaggc cttgagctga taatcctgag
    31861 tctctgctat agctgtgtgc agcttttttt caattctctc tattagctca gtagctgctt
    31921 ttacggtaaa ggtcgaaata aataagcaat caaccggaat acctcttaga atcttatcca
    31981 aaatgcgctc aaccataaca aaggtcttac ctgagccagc agatgctgat actaagatat
    32041 tttgtccact gctataaata gcctcaatct gctgcgctgt ccgcttgtgc gtcttatctg
    32101 ataaggcctc ctcctgctgc aaacgagcaa tagcctctgg cgttagaaag ccttcatcaa
    32161 tcctcatgct ttatctcctc attcattcgt gtcaagaaag cctgtctcct ttcttttgtc
    32221 ggtaggacga ctaggcgtct cgcgtaccct agatctaaat ccgcctcaaa gcgcgtgatg
    32281 gccttgagct ggtcaccctg aacagacttg ccgtctgcgg tataagggtt tattaggaaa
    32341 tgccctgttt taatctgctt caccgcagac aaatatagct gctcattata agccagcagg
    32401 gtttctagct catcagtctc ataaagtgtg ttgttaaggt gatagctgcc attagccaga
    32461 tattccttgg cttgggctaa aaaaatgccc ttataggtta actccttgta agccgcagct
    32521 actagctgat catcaagtgc cttaaagtca gacagactta gccttggctc ttgcatgtgc
    32581 aggtacatgg cgccaaacag gccctgcccc ttattcttta gggcagcaag ataggtcaca
    32641 agctgaggac tcaagccatt gtaaaaggca acaatgtcaa atacccttgc actggatttg
    32701 tagtccacaa tgcccagcct accatcagct agctggtcaa tacggtcaat aacccctcga
    32761 ataagcactt gctgacccag cgctagctca aaggcctcct cttgcttggt tatctgcagg
    32821 ccttgattaa ggtctaagac agaggctgtt gagtaagcaa tcccctttag gacctctaag
    32881 ctatatcgcc cttcagcatc agcctgataa acctgctgaa aagcgctttg ctgattaact
    32941 gctgcaatag ctgcgcctag cttttggtca aaggcagcat tagacctatc cttggttacc
    33001 aactcaaaaa tacggtgcag gtattgacca tgaatgcgag catctgggtg aatagactct
    33061 ggctcttgca gccctaggac atatttcaag aaatacttgt attgattgtt ataaaataca
    33121 gtcaaggccg atgaagacag attcaagggc tgctgacttg aaaagcgggt ctcaataacc
    33181 tcaggtgcta ctggcttagt agtcaaatga tgctcaaaag ctggaagact tagctgctca
    33241 tcggctagcc tacgtttcaa ataacgaagg gcaaccgtcc aaaagtttct gtcctcactg
    33301 gtcatgtcat ctgcaattcc ctgccgatta atagccacca agcgagacaa gagagcctta
    33361 taattgccaa tatctgccgc tgagtgtgac aaacggttct ttcctttttc aatgactgga
    33421 acaccaaggg caattagctc cttcaggtaa ggagagacat catctgagct attcgttaag
    33481 cttgtaggca ggcttaacac cagctcctgc gtcgctgcat taaacaggga aagtgctgtt
    33541 tggtgatttt tcttgatatt ttcaaagctc ggcacatcaa ggcgctggta agaggcagtc
    33601 tgctcattga tgcttgccct ttcctgatca gagatcaggc tggtgttttt tgtctgctta
    33661 ggaaaatggg agcgactcag gccaatcgca aacacaaagg gcttggaatg cggctccacc
    33721 agatcatagg atttgataga cacaacatct aaggtcgcag gcactgtccg ataatgtgct
    33781 gtctgcatgc ccatcttgat cagagctaga cagtctgcaa gggtcatttt ttcctgacca
    33841 aacacctgat aaaaggtctc taaaatgcct gtgaaggctt tccaaacctc ctcgtccttt
    33901 tccctatcag tctcccttct actgcctgct agtgcctcaa aattatcagc cagctgaatg
    33961 gtcttaaaaa aggtcattag cttatcaagt agggaagccc ctagctgctt ttgactctta
    34021 aagagctgct ggagaggagt caccacagca agtcgcagct gattcaaaag aggcaaagga
    34081 tactgacgtg aggaatttag ggtaaagggt cttgaaaatt tggtgaagcc ttgaatatca
    34141 gcaaagacca agtattgctc aagctgatcc agctctccct cttgaaagcg cccaaagagt
    34201 cctgatttta gtaagttgac aatatcctca cgtcgccaat tgtatctgcg gcctctttct
    34261 aaggattcga caaattgaac caaggggtga gcagacatcg gctcttgctt gccgatataa
    34321 taagggatct caaatttctc aaaaatagga ccaatttgca gctgataaga cgccacatca
    34381 cctaaaagga caagcatatc cttatagcga taaccctgat agagcttctc acgaatagcc
    34441 tttgcaacat gctcaagctc ctctttttga ttgagcgctt gccagatcac aaccttgctc
    34501 ttgtccttgg cactgagctg ccaatcaagc tttgaatagt catgattggc ttcaagaagc
    34561 tgtgttaggc gagaaaatga cacatcaaag accttttctg acgttgtgta gatcggcttg
    34621 gtttgaaatt gctgtgccag ctgttggata aacgcaaggc tcgcctcgta gagatttccc
    34681 ttggtaaagg ctagtcgata agccttttga ctgatatagg ctccaataac gatttcttca
    34741 caggcttcgt ttaagagcgc tagcagctgc tcctcctcag ctgaaaagcg ggtaaagcca
    34801 tcaatcacta atacggtctg ccttagctcg tcatctaggc tcttgctttt gatagcctca
    34861 gcaagctgag ccagcctact tgactggtcg taatctcctt gtgcaatcag ctgctcagcc
    34921 ttggtcataa tcgtgatcag gtcctcttgc ttttctggtc tatcaagcgt cgttaagtca
    34981 aaggctgtca gattagctgc ttgcaattcc ttatatagct caactaactg ggcaataaag
    35041 gcctgatctg tccgtagccg gtgaaaaacc tttagctcat cttcttgcag ctgcatgagc
    35101 acacgataaa aaatcatggc taagccatta tcatctaacg cttgtcgatt agctgcctta
    35161 gctaaggtaa aataacgcgc catctgctca aagcgggtca ccgtaatagc aaaggaaccc
    35221 tgctctggca ataaggctag gacagaacgt tccttttcaa aggatagaga gttaggagca
    35281 atataaaaga cacgatagcc cttatcagca taagctcttg cctctttgac taaaatctct
    35341 gtcatggaat agctaatctc tgtgtatagt aatttcataa aactcctttt atttggacct
    35401 gatacaacgt ctatgcctcc attataacaa atcagccttg cttttcccat tgttaatgat
    35461 ctttcaaacg ccacaagaag cgctcacagc atgaaaaaag cctaccattt cacatctgct
    35521 gctttgcgca agaaatgata aggctttgtc ttgtataggc tcaaaaaaca gactaagagc
    35581 tcctagttaa gctgccctgt gcttgtctct tgtgatctgt ccccaggcat tctttttacg
    35641 ctgataacca ataaagctgc tcaccttgat aagggttaat accgtatgaa gaacaaggca
    35701 ttggtagatg gcagcataga ttacccaagc catatcaaaa agagtaatgc tactattgtt
    35761 ttgcaaataa accctattta aaaacgatgt caacgcaata agcacacaat agcaaatata
    35821 gagcagcatc agtgacacaa aaaaggttgt gtttaattga tggcatagca aagacagcac
    35881 aatgataata acaccaaatg cctcaataaa aggagataaa agctcaaaca aaagatacag
    35941 cacataggaa atgagtaccg tcgctttaaa ccgacagctt acaaaaaact ggagatactt
    36001 tttcaagcat tgatacagtc ctaaaaacca acgacgcctt tgccgacaca aatccttcaa
    36061 gcgactgggc gcttggctcc agcaaatagc gtctgtttca tagccaatac gataaggaat
    36121 cttgttgtta tggcagaaaa aatgtaattt catcaccagc tccatatctt ctcccagagt
    36181 cccagtgtca taaccatcaa cagcaatcgc aagctctttt ttaaacagtc caaacgctcc
    36241 tgatatgatt aaattcccag cagcctggtc taataaaaca cgagctccaa aaaaggcaca
    36301 atcatactca attgcctgcg cacacgaaat aagctgacgc ggcaaatggt agtctacgat
    36361 cctcccagct gccaatgcta ctccctgcga aaccttgacc atgcccccaa cagcaatgac
    36421 agacggatcc tttgcagcag tctttgcaat acgcttaagc gaatcctcct gtagcatcga
    36481 atcagcgtcc atgcacaata aataatcgta ttgagcagcg ttaatcccaa gattgaggct
    36541 atctcctttg ccgccatttg ccttttcaag cagggtcagc ttgatatgct tgagctgctt
    36601 ttggcttaca gcctttagag ggcgtgttgg gatccgctga ttaatcgaac aagtcaccgc
    36661 ttctaaatga aactgctcct tcaagagctt ggcggtatga tctgttgacc catcatcaat
    36721 gacaataatc tcatagcagt cataatcaag catcagcaag gactccactg tttcgataat
    36781 ggttagctct tcattatagg ccggaaccaa aatagacact ggcggtaaag aaacatcacc
    36841 accaacaggc gcttgctgtc gcctttcata aaggtgaata gtcccaacaa ttaaggatag
    36901 cagtaaaaag ctcgcatagg caatcaaaaa cgctaaaaaa agatattggg agtatttcaa
    36961 tactaaaaac agtagctgca ctatcattct cctttaacat gcaatcactt gtgcttacca
    37021 ttcgccttac aaaagcgtct caaggtctgc ttcatcaaat acccgatatt aaaggcaagg
    37081 atcgctaagc aaacgattat ataaaaaaac aacaggtaat aaatcatctt atcttctcct
    37141 cttttcctgc cagacagcct gcacctgctg ataggaggtc tttaaaactt ctcttaccct
    37201 tggacgctcc cagctcaaca gtggatactc taccattgca atgacctttg attcctttag
    37261 cggtgcaaaa ccaatagcta ttgcttcaat ggctaattcc tcaacaccat agtgctcaaa
    37321 ataatcatcg tgtattttgt ttgaagctgg atcagaaaaa ttgagcagct gccagggaat
    37381 cctaagctca atcagacgct cgccaaaaga aatatcggtc tgcgaatcaa aatgagccga
    37441 gcctcgtttg ccattgccct gttttaattg gccggtaggg tagcgcttca gtcctctttt
    37501 tgcaatcgga acctgatcaa tggctgcaaa aataccatca tttctcacca ccatatcaac
    37561 catagtaaat cttggcgtat gcttgttagg gggaaagaca taaaagtcct ttccattaat
    37621 ctgcctaagg taattggcat cagtagcatg gtagcgctcc tgcaccaaga ggcgactgcc
    37681 tttgtggtca tcaacaacaa gggcaaaatc agcaaagcga tcaaaccgag cgctaaagcc
    37741 ttcaataacc ctgctgcctg ttttgggcgt aatgtctaag ggaatgagcc actgtctttg
    37801 taagggctgc ttttttgtcg attcaatagc aatatagagg tatttttcgt cctgatcaac
    37861 gaggagctgc tgcccatttt tcttgtaggt tagagctcta gaccactcat ctgctgcctt
    37921 ttgcccatca atagcatgcg tccttggagc atgctcaaag gttaagagac cataaccttg
    37981 agccttagac tgaacatcac cccaaagaaa gctttgatgt ttattggttg caaaggaggt
    38041 attccagctc ctagcagtcc aatcgtcctg ccagctatgg atcgttgcac cacagcagcc
    38101 agacgcaata aaggctgtgt aatctgccat caagcgctcg ccttgatcct tttctgtcaa
    38161 agggctggaa gtcgatatca tttggtccac acctctggct gtcgaatagc catagcccgt
    38221 cacaaccact gggacacgat gatagctcgt cagtagcttg acgtatccct gatataaggg
    38281 catgcgctta atatccccaa caagcctatc agtaagccct agacggtcaa atagcagata
    38341 atccctataa gccgagtgac aatccaagag cttataggaa gcaaaaagac cggccttaac
    38401 cttagcgctg ggcttaatat tttcaatcgt cagttgaaca tattttgctg cctgagaggc
    38461 aaagggatcc tgatagacaa agggatctga ttgaggcgta tttgaaaagc tcaccaagtg
    38521 ctgccagcca tatttgcggc tctcgtatga cgtgatttcc tccatgattt cagccagtat
    38581 agcctcaaac cgattggcct gaggtgtcgt tgcataatac cttcccttaa agcctacagg
    38641 cttggcgtga ttctgatgat tggtataggc tatcgtccca ctgtaccaat catcaccaac
    38701 aatatagccg agtagccatt tactcatatc ctgatcataa tgctgaagcc ctaaatccga
    38761 atgccagatc cgttttctcc catgaatcac atcaacacta gccctagctt cccttaacag
    38821 agtgcctaaa taagccttat ctaaggcgct gatagaagaa ttgtcatgat aagcatctat
    38881 tctaaagccc tgtaataggt acagaggatg acttgctctg tcattgtagc gtctcaaagc
    38941 atggtaaaaa gtgacgggca taataaccct taccctgatc gtatttgcac ccatagctgc
    39001 tatttgcttg aaccacctat agtaggtttt ctcatcaacg ctaaggtctc gtcgacgata
    39061 gcctgctatg gaactctcca catcaacacc cttgatgaga taaggagatc ccttttgatc
    39121 atatatgcgc ttgtccttgg tgtaaaagac tgtccgaata gctgactggt tagagaccgg
    39181 caggtacaag cgaccatcaa tatcacaaca ataatagctc aagccaatca cagacaagag
    39241 caaaccaaca aagattaaat atttcttcat cactacctac tccaataatg tattggtatt
    39301 tttagacggt gcactgtact gatagagcgt ctcaatatgc ttatccagcc atcgcccacg
    39361 acgtctaata aagtccttta gttgcttaac agaggcctca tagctactgt agttacgact
    39421 ggctggcaca aggtaattag tggcatcgct tcttgatggc actgtaaaca catagcccca
    39481 cttatgataa ttgcgctgaa tagccggacc taaaaaagca accgtagcat caatatactt
    39541 gatcaaataa tccgttgata aaacattctg tcggagctga tgataccttg tgaccaccag
    39601 cttaacaaag ctaggatcct ttagcagcat gcaaaaccaa ggagcatctg atagggtaaa
    39661 gtccgcctca tcataaggag cctcaatctg attatcaaag gcgttgttaa aatcccagac
    39721 caccagcttg agcttatcgc gcaaatcctt ataaagatag gttgaaaact tcccagcatc
    39781 aatatttcta aagaattcat tgataataaa atagtctgca aaggactctt ggtccagata
    39841 atcagtgtat tgctttaaat cataagaata taggagcttt tcgatatgac tgatatcctt
    39901 ttcaataaac tgcttttgct taggcgtcag acggtgcagg cttgggtatt taatgtctaa
    39961 agaggacaga cctgcttgat tcgtatagga tacgtaatga tcaagagcct gcttagcctt
    40021 gtgtcttcta tcccaaacaa ggatataagg cgttttatca gattttctat cacttttttc
    40081 gatgtttacc ctatgccgcc cctgctcaat actctccaca gccaaataca gaccacaata
    40141 ctgatgatcc accactaact cgcaatacct gacgttaggt gcataggtca tgatctcacc
    40201 ggcaatattg tagctaagat aatttcggac tagggtccga tctaaaaaag gaccatgcag
    40261 cacccactca gactccttgg acatgccagc cagcgagact gcctttggct tagctctttt
    40321 attgataaac cttagcttta aggatttctt gtcaaaatga cgtgacgaat tgcccctata
    40381 agcaatcaat gctgtcaagg acaagcgcgg agactcagac aggctgtgct ctctatctag
    40441 ctgatcacga agcgagaccg tcgttttaat ggttttttgc cgctttgtct ctccctcgta
    40501 ttccctttgc tctggaatct gctgatgatg agtgtcaatg ctaataatcg gcaaatgaga
    40561 gctaaactcc ccagtgcttc tggagctctt tttgaccgtc tgcaaatggt gatgaatacg
    40621 ctttgcagag gtcttaggaa aaccgatacc acaaatagca gctagcaaga gacacaccag
    40681 cacaatcaca taaatcgtct tttctttcat ttacgtcaac cagttatgtc atcgctttga
    40741 ctaacaatat taaaataatc aactcgcccc agctgataaa cagcctcagt taacggatta
    40801 gcctgctgat aggtgctgtc ataatccttt cttgacagct caaagatcat ctcaatatca
    40861 tcagacgtgg tgtttttcac gctctggatc gccttacccg aaaagtagtt aaacactaac
    40921 cgctccagct caatttccat ttgcttatca cagcgaacaa tcaacaacag tctattgtca
    40981 tttctgacag ctcccataag caacaaaagc ataaagatca cgctgctacc agttgcagcg
    41041 acagtataat caccaacacc acagcaaatc ccaaccacaa tcgtccaaaa aatatagact
    41101 gtatctctag agtctttgat tgctgtccga aaacgcacaa ccgacagcgc accgaccata
    41161 ccaagagaca aagcaacatt atttccgata actgtcatga cggttgctgt taagaccgtc
    41221 aaggtcatca acgaaacatt aaacttcttg ctataggcag tcccagtgtg ggtataggca
    41281 tatgacatat aaatcacaat acttaacaag gctgcagcaa caatatgcag caaaacatct
    41341 tgaaagctca aggtcccacg ctgttcaaag acatgtctta ataattgttt catcttaata
    41401 tctctcctaa aaacgataat gcttgctgat agctctcccc atgcaatact tgcttgcact
    41461 tagctcgcta ccattaacag actccaaaag ctttttgata taagacaaca aaaagccatt
    41521 atacttgacc tccaagatga ccaaataggg atctagcagg taattctgag gcagatgatc
    41581 tgaaaaaata tcagcattgg tctcagaccc gataatatga tgatcaaagg taatgcgaat
    41641 attgttttcc tttgccacaa atgccttgcg ctggtattcg atcactgttt ttggctgata
    41701 gagctgcatt gacatgcgac tatagcattc agcagcaaag cgatcaggat aagtcagcaa
    41761 tatagacttg tctcccttaa tcaacaattg agcgtctgct ctggtcaacc tcagagatcg
    41821 ctttttttga ttgctccctt gcttttgctt catctccaac ttagcaaatg agctctgact
    41881 accgtaattg cgcaggcgaa tttttcgcct aagctcaata ccgtcctctt tttcctgcca
    41941 gtcaacgtcc tccaaagaat caaaatacaa ggatcgaatc acatatccct cactagagct
    42001 atgagcatct agacgcaaga gcttggaaaa ttcatgcgat aagcgataat aatcctcaat
    42061 ggtaatcaaa tacttttttt cttgacgcaa tacctcattc acgccagtgt cctccttttt
    42121 cgtctgtaag caatgcctta acaccaagct gcctgtaaca gcagccaaca aacctgtctc
    42181 ataaataagt cagggcaaat aaggtgattg ttggctctac aagagtcaat cacctgccaa
    42241 aatagtaaat cctgccatct gttgaaataa tataaaccag ctgatcgtct tgattgcaag
    42301 acaggcgctt ttgtgactga tctagctgtc tgctgctaat atcagttgca ttagcctcct
    42361 tgagcatggc ctgcttgagc tgttgctgga tttttctggc ttgcagctca gaaatctcaa
    42421 agctgccatt aaccttttga gccttgtgct tgtagaccag tgccacatgg tctttagctg
    42481 ttgtcctagc agtcgacagg agcccttctt tgttgagctg agtatgctct cctacatcaa
    42541 tggcaacata gtcatagggt gcccgtatcc ggtgcgctgt tagtattgag gacaaaatcc
    42601 ctgtcacaag gcagatgctt atcgtagcca ctatcatctg ctgccgctgc ttacgaatga
    42661 accttgaaaa agcacagacc tccgcctgat attcctgaag ctcttcttca accttactgt
    42721 aatcctgtct aagatcagcc aagtcagtct gacagtcctt gcagcttgtc agatgagcct
    42781 caacaaccgc tctactataa tcactcaacg tatcatctac atataatggc aacaaatcct
    42841 ggatcaactc acaatcatac ttcatagcca tactcctctc gtaattgtct tttaatatgt
    42901 tttcttgccc taaagacaag aaccttggca gaggatactg tgatgccaat atccttagct
    42961 attttttcat aggaatctcc cgaataaatc ctcgccagaa agacagcctg cattttctct
    43021 ggaagattaa aaataatcgt tagtgtaatc tctaacagct cccttcttgc tatcttatca
    43081 agtggttcat catgcccttt agcatcaacg atttctaagc tttccatcga catattctca
    43141 tattttttct ttttaatttc tgtaaagaag gtgttctttg caatggtaaa taaccatgtt
    43201 ttgattgaac tatccccact aaatttagca atattacgat aagcctttag aaaagtctct
    43261 tgagtaatat catctgataa actattttga taacagcaca gcttatttac aaacctataa
    43321 acatcatctt tatattctaa atatatgtcc tcaaattcca acagcttgtc tcctctcaat
    43381 acacccttaa ccattagacc gtccaatctg ccaaaagtta cagattaatt taatttttag
    43441 tataagctgt catcaagtca gataaatagt aatgatctat catcttatta ttgactcaaa
    43501 cgacaaatta tattgcattt tagtataagc tgtcatcaag tcaggtaaat aacaaggaca
    43561 tatcatctaa catttgatcc agacaaaaaa gacctgattc tgtaatatac agaaccaagt
    43621 ctttctcaat agacattgac tagatgattg atttatagcg acatagctag ataggctatg
    43681 acttaccgtc ttttggattt ggagacaagc ccgccaagac ctgccaagat accactgcca
    43741 gcaagagcca ataaagcatc tagctgacta gtgcctgttt tagggagagt cttagctgag
    43801 aactgagaaa cctctccagc agtctgagca gcaactaatt tctcctgatg atgggctgct
    43861 tgatcagtca ttgcacctaa agtcccctta tcagactggg acgccctaag acggataatg
    43921 gtagctgtta agcctgatag cttgaccccg tccttggtta gcacaacccc ctcaggactt
    43981 gccagcgcct cggtgcctgc ttgcttggca tcgacgataa cctcaccagc aagaagagcc
    44041 tgaaactcac cagttagcct aatggtacgg tcattgctat cagcattgac aaagacagca
    44101 taaacatcac cattgcttgc tgttgtctga taagcaatca ccaaatcctg tgccttgatc
    44161 ccatgctcat ttggaacagt gatcagcttg accttctggt ctatctcagc cttacttgcc
    44221 aagcgaaagg catctgtcga acggcgcagc gcaatcaatc ccttagtaaa ggcctgactt
    44281 gtcgtgcttt cagggtagcg ctctgtatcc gttgcctttg cccagtcaaa atgattaatg
    44341 gcatctgtcg aatcatagga atcatgaata aagtatgggt attcaaatgg tgttccgtcc
    44401 tcattgacca agaggtgtga tttatttggc accttgtcat cagcgacctt gcccttatag
    44461 gcttcgtcct taaattgctt tgtacgacca tattcctgac cagcatgtag gaaaggggtg
    44521 ccttgagagg ttagcaccaa gaggttccct aggcgcaagc gacgatgaat ctctgccgca
    44581 tttgctgcaa cagacggatc ctttttaata gactgggcga taatatcaaa caaggtcagg
    44641 ttatcatgtg cagcgatata ctgaatcaca tcacccggat catcagccaa aaagttagtc
    44701 ggctgagcct tgatattatg aaaaatggtc atgatatccc tagcaccgcc cgtaataaag
    44761 gctggagagc cttcatttgg aaagcctgat ttgagctgat tgcgaaaatc atctgagaag
    44821 gaggcaacgg tatctgtctg tgacatccag ctttggtccg caggctgctc aggcatgtgc
    44881 tcatcaccct gataggtgac ccagccctca ccaagcatga tgatattcgg attaagtgcc
    44941 ttagctgcta aaaaggcttt ttcaatagct gctgcatcat ggtcccccat catgtcaaaa
    45001 cgaaaaccat caaccttata ctcatccacc agataagtaa tcgaatccac caaaacacga
    45061 cgactcatgt aatgcgttgt cccaagtcgt ccaccaccaa atgaggtcct agcagtgcca
    45121 tcagcattca taaagtgata ataattcggc tccaggtcct caaaaatatc aacattagct
    45181 gtatgattgt agaccacatc aaggataacc cccataccac gcttatggat ttcattaaca
    45241 agctgcttaa attcctcaat gcgcttagct gggtcggttg gatcagtcga atacatacca
    45301 gtcaaggcaa aatagctttg tggatcatag ccccagttgt aattattatc acttgagctg
    45361 taggtcagca tacgctcctt gttggccaat tcgttgacaa aataatagct catcacaggc
    45421 agcagttgaa catgcgtaat accaagctcc ttgagataat ccaacttttc aacaaaggca
    45481 gcaaaagtcc caaattgagc ctttagatca ttagcaatcg cctgatctga ggtaaaatca
    45541 cgaacatgtg cctcatagat aatggcgtcc tcacgcttat gaaagccctt aatatcagca
    45601 aaggccagct ccttatcccc aatagcagca ggatcaacaa tggccgcctt agccacctta
    45661 taggacgggt ctgtcttagc aagctcgctg ttccatgccg ctaacgattt ggcataaggg
    45721 tccagcacaa ggacagactt gccatttcta gtaatctcat aatgatagaa atagcctcta
    45781 taatctgaaa tcccaagtcc gctatctgct gatagagtga ttgaccactc tcccttatca
    45841 ccctttgcta gagcgagatt accaatcacc ttggtctgat cagccttatc atacaaaaca
    45901 agtgacacct tatcagcact tggtgaccaa atcgtcagat caaccttagc acctgcttct
    45961 ctcacacgcg ctcctagctc accgtcataa gcatacaggc tatccttgta ttgccaattt
    46021 ggcctagcct ggaagctctc atgatgaaag gtcaccgtat aagtggccac tgcttgacta
    46081 aaatcacctg tgatgacagc cttatgagtc ttttcatcta aggtgatatc agtaatagca
    46141 actgcttcct tactgtcagt gctgattttt aattctttta aaaggctttc cttatccaca
    46201 tctgctagag tcgtaaagct cgcctcaata ctgcttgggc tgacctgctg agcaccgatt
    46261 aatctaactg tattaacaaa ataagggttc gtataaatgg ttggatcctc gtctttcaag
    46321 aaaatttggg tgtgattctt taaatcttta aaaatataat cattgggctg aattttaaca
    46381 gcgtcacctg tctgacgctc atctagcaag agaaagccta gctcattggt atcagctagc
    46441 ttgacatcta tataagcacc atatcgaccg acctgcttaa aatcaatacc atctggccaa
    46501 gcgccctgct gactagtcat tgacgcatca gcacttcccc aaagccagag cgatttgttg
    46561 tcataatggc catcactgcg ataataattg atacggatat agccctgagc cagcggccga
    46621 tagtaagaca gctcctggcc atcaatccag acctcattca tcttagggct gagaaggtct
    46681 atggttcgat cgcccgtcag attgtctccc ttagtgttat tgatcaaaaa gctaacctta
    46741 ttggcttgat tggctgaaag cttaacgtcc atgtaatagc catagtcatc tgtcttcgct
    46801 agactaaaat tggtagcccc agtcggccag cctcccagct gatcagatgg tgtctcaaca
    46861 tcgtcccaca cccaaagacc aagcgaggat aggtcttgag ctggcagggt cttgaaatgc
    46921 agccgcaagg tctgctccgc tatcggctcc tctgagcttg tagcttctgg tgtctctaga
    46981 gagctgtctg tcgtaacaga cactatcgat gatgaaggct gagactggtc tgtagtttcc
    47041 tcatgcgcct gatcctctac aagaggtaca gctactggct gaacttcctt gacagtatca
    47101 gcattgacag cagctgacac cttagtcaca tcagaaatac cagcaatatc actaatgtca
    47161 gtagcttctg gtagctcatt tgagccttgg tcagcagcct ctgacttgac catgaccgca
    47221 ccatcagcag gctcaacact cgtcagactc tcagctgctg ctgtgatctg cccactagct
    47281 gtccccaaag aaaaagcggt tgcaatagct accgaagcca ctccaagctt aagcttacga
    47341 atgccaaata attgacgctc ttcaaacagc gcttgatttt cccctaacct tttcatcatt
    47401 cctccgtcct tatcctgata gttattaaca ccttaagtat acaaaagaaa tcacaatagt
    47461 gcaatcgttt tctttattga aaacaatgat atttatgaac aaattagaca agaatcaacg
    47521 caagcgattt ccttactgat aaatacctgc tcccctcact aagaccagcc cactgcaaag
    47581 cagaaaagta gcctaaagag ccttagtaac agataaatga gcttaatgtt gcttcatcaa
    47641 ctagctggct gcaaccgttt tgctctgatg tggtaacgtc ttgtcatcat gactaagctt
    47701 gacaaaaaac gctgttagtt acataatcaa cggtgcttgg tagccttcca ttactccttt
    47761 gattgttata ccctaatgat acacaaaacc tcagttttta tagtagaata ttacactttg
    47821 ttttgacaaa gatgtttaat cttgctaaaa taaacttatc aatgagggag taccaatgat
    47881 gacattcgaa ttcacatcgt tattcgattt acaaactgct tttccaacag agcaggcttg
    47941 cataaatcat ttagaaaata tcacttgggg tgacgtggtg atcagccctt ttgacgctac
    48001 ctcaaaggtc tataaatgca agggaaataa ataccgttgc aagaatacag ggaagtattt
    48061 cactgtcaaa acaggtactc tttttgataa tactaagatt aagctacaaa aatggtttat
    48121 ggcaatctgg cttgtgactt ctcacaagag aggaatctcc tcagtgcaat tatcaaaaga
    48181 gattgcagtg acacaaaaaa cagcatggtt catgttacag cgtattcgta aatgctttgg
    48241 ctctgaaaac tgagatccac ttggtgacgt cgttgaagta gataaaactg atattgatgg
    48301 taaaaataag aaccaccatg atcctaagaa ggcaaaaacg ttcaagaacc atccttctct
    48361 gaaagataag tcggcagtta ttggaatggt gcaacaaaaa agtaaggcca acgctcatac
    48421 aatactcgtg attactctga tagtcggcgt tttatctttt atcagctaat gctgatatgc
    48481 gaacaactta taaggagctg atcaatggtt aaacatgcaa aaactaacct acactttgaa
    48541 ttagaaagat ctatctctcg caaagttgat agtaaattga tagcctatca agtcagtctt
    48601 tcagatggct tttatgacaa atacaccaaa ttatgggata aaacctattc atttgatttt
    48661 gtcatcaacc atcgtgcgtt ttatgctcag ttgaccaaaa gatgtgttta cgatgtcctt
    48721 ttgcaaactt tggaaaaaat cagtagaaaa gccattgcaa agcaactagc agagcttgaa
    48781 gccttggttg atgtttcgga aagtaaggaa gactttcaga tatttttcga gaaaaaatac
    48841 aaactatcat ttcctgattt gaagaattgt gtttatccaa agaaaaagga actttccgat
    48901 tttgatcaaa acctctggat agctctacat tataacccta gaaaggagag ggatacataa
    48961 tgacaacatg gtatgattac atggtaagag ccagcgaaca ctctggaagt gatggagacc
    49021 tctggtttcg ttacctttac aaggttatca aagacaaaga aaccaaacta actactgatg
    49081 atgtggagca gttattaaaa aatccgaatc taactccttt tcagaaggta actctgcaag
    49141 atgctttaac agaaggtacg catacaagag agcatgtttt acaggcaaac cgtaaaagtc
    49201 agccaaagga tattttgaaa ctctttagag agggaaacta tggataaaaa aatcttattc
    49261 aaagctctga atacagaact agctaaagaa aatattagcc ttgacattat ctgtgtcggt
    49321 ggttttgtcc ttgaatatta caatctgcga ggaacacaag atatcgatgc cttttatcaa
    49381 gaaggtgtta acatcaggca gatgatcaaa aaggtgggag atgagtttgg cgttaatgaa
    49441 cctgatgagc tttggcttaa taattcagtt gccaatctta atagaatacc acctaaaacg
    49501 atttgtgaga cagtatttca ctattctaac ctaattgtcc ttgtcccacc cttgtcttat
    49561 attcttggaa tgaagctaga aagcggacga gatagggata gacaagatgc cggagacatt
    49621 attaagctag ctaatatccg ttcccctaaa aaacttatca atacacttga agagtatgat
    49681 tttcaacctg atatttcaat gattttagaa gtctttgaaa tagcttatgg catggaatgg
    49741 ttagcaaact atatgaccga acacccagaa gaatttaggc attattaaaa gacgatttct
    49801 gtttggaagt cgcctttttt gatgtttttg aaaacacctt gagattagtc taaactaatc
    49861 tccataagca aaaaacagct tagccccgtc tgggagtaag ctgtttttgc tgtaatgtat
    49921 gagataatta ggctaacatc aatcattaca taaagggaat aaagggttaa tgtttcttgc
    49981 gtttgcgtga tactacagct acgcctagac ttgccaatac ggcaagggct gctgctgtaa
    50041 agaatggagc tgttgcttct cctgttgacg gaagcttgtg ttccattgct ttaggtaccg
    50101 ctggtttatc tcctttctgt gcttc
//
LOCUS       DARYMD010000009        49114 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYMD010000009 DARYMD010000000
VERSION     DARYMD010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49114
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(219..689)
                     /locus_tag="TU818_000456"
                     /pseudo
     CDS             complement(219..689)
                     /locus_tag="TU818_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            904..1125
                     /locus_tag="TU818_000457"
     CDS             904..1125
                     /locus_tag="TU818_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL0923311.1"
                     /translation="MDTKFTALTEEQLKSVEGGKNGVVKLPGGTGVYCWNTGKNSAKC
                     GMDWSVAGPYVGKIIVNGWVNHGPWASRP"
     gene            1155..1448
                     /locus_tag="TU818_000458"
     CDS             1155..1448
                     /locus_tag="TU818_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0923312.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASTPAKHRGLISIPFWLSNIFR"
     gene            2585..4417
                     /gene="lepA"
                     /locus_tag="TU818_000459"
     CDS             2585..4417
                     /gene="lepA"
                     /locus_tag="TU818_000459"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL0923313.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            4959..5396
                     /gene="msrB"
                     /locus_tag="TU818_000460"
     CDS             4959..5396
                     /gene="msrB"
                     /locus_tag="TU818_000460"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL0923314.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSKPIQHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPKEAGGLRYCINSAALKFIPYDQMEQEGYAEWLGIFDKS"
     gene            5684..6703
                     /locus_tag="TU818_000461"
     CDS             5684..6703
                     /locus_tag="TU818_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL0923315.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALVYQKRDYTKSGIALTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            7047..7472
                     /locus_tag="TU818_000462"
     CDS             7047..7472
                     /locus_tag="TU818_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL0923316.1"
                     /translation="MKRKFLIGSHGRMASGLKSSIDILAGRGQELQVIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMDSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            7487..7978
                     /locus_tag="TU818_000463"
     CDS             7487..7978
                     /locus_tag="TU818_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0923317.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNSKVSLSQ
                     LIK"
     gene            7996..8805
                     /locus_tag="TU818_000464"
     CDS             7996..8805
                     /locus_tag="TU818_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL0923318.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            8802..9629
                     /locus_tag="TU818_000465"
     CDS             8802..9629
                     /locus_tag="TU818_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL0923319.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGSMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGVVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            9819..11453
                     /locus_tag="TU818_000466"
     CDS             9819..11453
                     /locus_tag="TU818_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0923320.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLIFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKALLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSFLRISMDNEEGHYLLLI
                     KPIKIDHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQFDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMILDMQAISRQEKNAIDLQSQDEFQYLSVQINQMISRL
                     QALHQKTLALEKQNVSFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIAVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFIKVELIFCQRDERFLLTYMVKE"
     gene            11457..12242
                     /locus_tag="TU818_000467"
     CDS             11457..12242
                     /locus_tag="TU818_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0923321.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGAKLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQRSDRSSL"
     gene            12266..13276
                     /locus_tag="TU818_000468"
     CDS             12266..13276
                     /locus_tag="TU818_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0923322.1"
                     /translation="MAIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRAFGQSTSNRPIRKDAKASQDMKPLDDIITLKEDYDYITRHKKDILERYNQLRKT
                     TD"
     gene            13529..15313
                     /gene="uvrC"
                     /locus_tag="TU818_000469"
     CDS             13529..15313
                     /gene="uvrC"
                     /locus_tag="TU818_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL0923323.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEVFIPETIDETLVAAIVPARIVKPQRGEKK
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQAPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALFDHLTSKSEV"
     gene            15441..16043
                     /locus_tag="TU818_000470"
     CDS             15441..16043
                     /locus_tag="TU818_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL0923324.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDN
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            16124..17533
                     /gene="pepV"
                     /locus_tag="TU818_000471"
     CDS             16124..17533
                     /gene="pepV"
                     /locus_tag="TU818_000471"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL0923325.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFVGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFTAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHIPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(17800..19176)
                     /gene="mnmE"
                     /locus_tag="TU818_000472"
     CDS             complement(17800..19176)
                     /gene="mnmE"
                     /locus_tag="TU818_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL0923326.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKD
                     LTTVASHTLNYGHIIKPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLISDTRQEILNTLAQVEVSIDYPEYDDVEEMTTALLRDKTREFQTLLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQIFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            19448..19669
                     /locus_tag="TU818_000473"
                     /pseudo
     CDS             19448..19669
                     /locus_tag="TU818_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
     gene            19792..20106
                     /locus_tag="TU818_000474"
     CDS             19792..20106
                     /locus_tag="TU818_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL0923327.1"
                     /translation="MVVLQNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRS
                     DASSAIDLSHNVSAQVVGIIASMSQHIQSVSASFQAMDLQLGKELGRLENRRRFSLND
                     PK"
     gene            20111..20443
                     /locus_tag="TU818_000475"
     CDS             20111..20443
                     /locus_tag="TU818_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL0923328.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYEELSNLAAQLLTAAAT
                     TFRSSSDSHLFEGALAEECYLKRKTQASLEQSHEELLGEQRRLYQEEEALTRQLKLVK
                     GKERANEH"
     gene            20445..22043
                     /locus_tag="TU818_000476"
     CDS             20445..22043
                     /locus_tag="TU818_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923329.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYKSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQELPNYSYITNLKSGASNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNIGIRQTKTSWNGTSQTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLQQAAEKLSRETGIKYEDAYRFVMDGVLSDENKNKIKSVKKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKGKHFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKELSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGKVGKAASKVLKFAGKGLKVAGWVGAAINVKDSVETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRVTGAVIGQAVIPIPGVGAAIGSVAGSILGAMAGSW
                     IGSTINDNLDKNVKPKQSGRSLAW"
     gene            22037..22723
                     /locus_tag="TU818_000477"
     CDS             22037..22723
                     /locus_tag="TU818_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923330.1"
                     /translation="MVMLMRTLLFPVDNGLDSGLTGDGYAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPSLKRQHGYFKTMYDNTIRENDGVFNNLSVPFIGLYVA
                     FLIAFSVIPIFYSQYLQQNSFWSYLGNLVGSSILISLVPNFLWNVLVKQLIYIKLIRK
                     TKEKILKNET"
     gene            22745..23431
                     /locus_tag="TU818_000478"
     CDS             22745..23431
                     /locus_tag="TU818_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923331.1"
                     /translation="MVMLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIIVRRLGVFSGDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEKEPDLDRQLYYYRTMYDNTIHDNSGVFNNLSVPYVGLYIT
                     LFLIFLIIPLCYHFYLHPSSFGDYLAALSVTSLLISLFPNFLWNGVLKHVIYVKLIRQ
                     TKERILKNET"
     gene            23453..24130
                     /locus_tag="TU818_000479"
     CDS             23453..24130
                     /locus_tag="TU818_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923332.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQATKQ
                     TIEKQQALTSNLLIIASCLSPVTVAGMILLSRSFPIFEEDLSEKIDTYAPIILGVVLF
                     LAFETLMLAIRGRDPLAEKEPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            24137..24451
                     /locus_tag="TU818_000480"
     CDS             24137..24451
                     /locus_tag="TU818_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL0923333.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
     gene            24899..25582
                     /gene="rpiA"
                     /locus_tag="TU818_000481"
     CDS             24899..25582
                     /gene="rpiA"
                     /locus_tag="TU818_000481"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL0923334.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMK
                     GDKRLITDMQNFIIDLNLGCIENPCEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
     gene            25660..26871
                     /locus_tag="TU818_000482"
     CDS             25660..26871
                     /locus_tag="TU818_000482"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL0923335.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            27084..27893
                     /locus_tag="TU818_000483"
     CDS             27084..27893
                     /locus_tag="TU818_000483"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL0923336.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRETARSVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            27984..28769
                     /locus_tag="TU818_000484"
     CDS             27984..28769
                     /locus_tag="TU818_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL0923337.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQTANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNDLFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKRLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLIRLAVFSGVNYIKEPFYFDVVNAVIEKELLDSAKP"
     gene            complement(28902..29810)
                     /locus_tag="TU818_000485"
     CDS             complement(28902..29810)
                     /locus_tag="TU818_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL0923338.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNPKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            30150..30599
                     /locus_tag="TU818_000486"
     CDS             30150..30599
                     /locus_tag="TU818_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923339.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEESAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
     gene            31220..31912
                     /gene="pyrF"
                     /locus_tag="TU818_000487"
     CDS             31220..31912
                     /gene="pyrF"
                     /locus_tag="TU818_000487"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL0923340.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPV
                     KAYHQIKAEWNR"
     gene            31972..32607
                     /locus_tag="TU818_000488"
     CDS             31972..32607
                     /locus_tag="TU818_000488"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL0923341.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKEPFTWASGITSPIYTDNRITLS
                     YPKTRSLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMDLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            32659..33402
                     /locus_tag="TU818_000489"
     CDS             32659..33402
                     /locus_tag="TU818_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0923342.1"
                     /translation="MTYKDLLEIGETSYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            33637..35091
                     /locus_tag="TU818_000490"
     CDS             33637..35091
                     /locus_tag="TU818_000490"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL0923343.1"
                     /translation="MIFKDATEMAQAVREGRVSPSALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYVVQ
                     RLEELGFIILGRSNTPEFGFKNISDSRLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQFQP
                     SKELIDKLAKAECYPSSQRLALVEAMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGIARQFERAGLLKLPG"
     gene            35211..36077
                     /locus_tag="TU818_000491"
     CDS             35211..36077
                     /locus_tag="TU818_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL0923344.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            36105..36758
                     /locus_tag="TU818_000492"
     CDS             36105..36758
                     /locus_tag="TU818_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0923345.1"
                     /translation="MLNLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRSYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            36889..37296
                     /locus_tag="TU818_000493"
     CDS             36889..37296
                     /locus_tag="TU818_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0923346.1"
                     /translation="MADSIVFRKNHMISTQAFARVLEASGIKRPTKDEARLSQMLKHS
                     NYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQGQGIGKQLLSFISEDLGDAV
                     ALVLLSAPSAMSYYPKLGFEQSDKAFIIPRKPF"
     gene            37308..37961
                     /locus_tag="TU818_000494"
     CDS             37308..37961
                     /locus_tag="TU818_000494"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL0923347.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLR"
     gene            38193..39467
                     /locus_tag="TU818_000495"
     CDS             38193..39467
                     /locus_tag="TU818_000495"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL0923348.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEVEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPSHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(39521..40168)
                     /gene="plsY"
                     /locus_tag="TU818_000496"
     CDS             complement(39521..40168)
                     /gene="plsY"
                     /locus_tag="TU818_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL0923349.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            40301..42250
                     /gene="parE"
                     /locus_tag="TU818_000497"
     CDS             40301..42250
                     /gene="parE"
                     /locus_tag="TU818_000497"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL0923350.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIATAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PVVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            42352..43167
                     /locus_tag="TU818_000498"
     CDS             42352..43167
                     /locus_tag="TU818_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEL0923351.1"
                     /translation="MKLDICQQSYSLQWGGTYYFALTDYPNIKAWELEKLAAFCAYEK
                     WNHRQTDISCQDSKLLEEVHQFLEAHACAYLFRPSCKLVASTFNINGEAVCCPYLSHT
                     CTVAAALSIFKTGRLLSAVRAFGVTAQELARSDRNAAGDPADYFHYVMLGWSNTTSGY
                     RLAMERLLNRMPNEKDLREHFVPGVSFHYSYSDICQMKGYVFDGYHPAKIKDELSLEE
                     LQACIIPKSWQQRFEAIIPKALRSRVHYLDYKGEGLVEWSDRVYQLLRVISDS"
     gene            43642..46101
                     /gene="parC"
                     /locus_tag="TU818_000499"
     CDS             43642..46101
                     /gene="parC"
                     /locus_tag="TU818_000499"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL0923352.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVIYMIDHPNAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKSRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPDIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGDEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAIANFAADELVIYAELIQSFEEGLYISVTQHGLIKRFERKELTPW
                     RTYKSKSIKYAKLKDIDDRIVAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLPVLRELKTK
                     PHRVFLAGMVKGDTTTGTIDLFTHDSEDTASDQQLEVISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            46199..47224
                     /locus_tag="TU818_000500"
     CDS             46199..47224
                     /locus_tag="TU818_000500"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL0923353.1"
                     /translation="MMTTAIDWENLGFEYRKLPFRYVSYYKDGKWDAGRLTEDATLHI
                     SESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFID
                     AVKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFIVFAMPVGNYFKG
                     GLAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTK
                     IEEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLD
                     RFVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPE
                     GWIVAID"
     gene            47292..47522
                     /locus_tag="TU818_000501"
     CDS             47292..47522
                     /locus_tag="TU818_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL0923354.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            47583..47663
                     /locus_tag="TU818_000502"
     tRNA            47583..47663
                     /locus_tag="TU818_000502"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47617..47619,aa:Tyr,seq:gta)
     gene            47702..47773
                     /locus_tag="TU818_000503"
     tRNA            47702..47773
                     /locus_tag="TU818_000503"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47734..47736,aa:Gln,seq:ttg)
     gene            47901..49103
                     /gene="rpsA"
                     /locus_tag="TU818_000504"
     CDS             47901..49103
                     /gene="rpsA"
                     /locus_tag="TU818_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL0923355.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRHQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT        14134 a         9102 c        11467 g        14411 t
ORIGIN      
        1 ggtgtggact aaaacaagtg ataaagtcgg gaatgacttt tgtaggcata atttcacctc
       61 gtgacgatac cgttacttct ttttgaccaa gaaaagaaaa tgaaagtaaa aatatgacga
      121 ataatgttaa tggtataata agaattatcg caaaattatg atagcgtcgc tgataaaatt
      181 cagcacttct aaacagattt ggattcatga atatctcctt acttactaaa taaatgatga
      241 tagaagcctt gatgcgtcat taattcgtta tgcgaaccta tctcgattat ttttccttta
      301 tcaagtacaa caatttggct agtacgttca gcagtactaa gacgatgggc aacgaaaata
      361 atcgttttct cggtcattga cattaggtta tcaatcactt ttttctccgt taagacatct
      421 agtccgcttg tcgcctcatc gagaattaga ataggagact tggttaataa tgctctagct
      481 aatgcaattc tctgtttttg tccaccagaa aatcctgccc catcagatag ttctgtctga
      541 tagcccatag gcatttgttc aatatcttct ctaatttctg ccatatcaca ggcattgata
      601 atatcctctt gagtaatcgc ttggtttgca ccgagagtaa gattttctaa aattgatcca
      661 ctaaaaatat aagcttgttg aggcagatat tggttatcga aacgtcctaa atggtaatct
      721 gacaaatcta tcaaattatc tcaaacggtt gaatttaagt cttaagcggt aaatttttcc
      781 catttaggac gtttcgatga ctgtttagga aatggagaac aaattttaac cgaaagtgtt
      841 atactaagtc tgtcaagctt gcaaccggac aaaataaaaa cacatataaa ggaggtattc
      901 gtcatggata caaaatttac agcgttgact gaagagcaat tgaaatcagt tgagggtgga
      961 aaaaatggag ttgtaaaatt acctggaggg accggtgtat attgttggaa tacaggaaaa
     1021 aatagtgcaa aatgtggtat ggactggagt gtggcaggac catatgttgg taagataatt
     1081 gtcaatggtt gggttaacca tggaccttgg gcaagtcgtc cataatttta atttatatag
     1141 agaggtgtga aatcatgaat gaaagagatt tagtacagct gatagaacag actctaaaag
     1201 atgaagaggt gcaaaataat gtcacttata ggaatctttt ggaagaaagt ctccagcaat
     1261 tatcactcaa aaagcctgtg tatttagtta gtaccaggtt agcaggacat atttcaacct
     1321 atctaatgac aaatcattat gaggcaccaa aagcgattat agttcttgct caatctatcg
     1381 catcaacccc agctaaacat agaggtttaa tttctatacc attctggtta agtaatatat
     1441 ttcgttaaaa aatattttca gatcaggatt tagaaggagt tgtagattgg caatgcactc
     1501 ataaaataag acacattttt tggagttttt tgcttgaact cctaactttt acattagtct
     1561 ataaacagtc aaaggaagtt ctttcaatct ctcaaattgc aaaacaattt tggctatatt
     1621 ttaaaagtac aattttgatt ccaattttag ttacaatcat tcttataaag gagattttgt
     1681 caagtacatt acaaataatg atttattttt accttaatgt tgttgtcatg tgctacgcta
     1741 ttggaatgat cttatcgtta ggttatgtga tttcacccaa gcactctata ttcaataaaa
     1801 ttaaaaatat aaaattaaat aatagagtat cccaagagat tgccgaatcc caatttacca
     1861 gtcttttaga gcgaagagcg acttgaagaa actgataaat ttatttggtt ttctgctaaa
     1921 aatcctgcca aaaaatcttt ggcaggattt ttattttact aagagatatt taggagtggc
     1981 tttgtcattt aatgcagatt atgatatagc aggagacata ttgttgaagc tgtctatgtc
     2041 acttttggtg gcaggtaggt cttattggaa ttggtgactt atgacattta tcggtggctg
     2101 taagcgtttg actttttcac gtttcatagt ggtccgctct ggaatgagtg ggtatttttt
     2161 cagaatatga tcaaagatag atgacatgtt ttacagcagg ctatagctgg tatgatttgt
     2221 ttaaaaaatc aaggccaatg ataagtgctg ggtgacataa gtcttatggc tttacttctt
     2281 gttagcttgt gtcagcaggt gctgagtcaa tcgttgtagg aattatcgta aacctaacag
     2341 tagctgctgt tctatttgtt tattttctgg tttctattca aatttctaaa atgctagggt
     2401 aacaaatatg aaacaagcaa gtggcgtact gcgaacagct tgataactta ttgcctgctt
     2461 aaagagggtg ctgttatgct tggttttatt aggcttatgg catgggatta aaaggttgct
     2521 gtagcgccat tgtcattatt ttggtacaat aataggtaaa agactaaatg tataggaaaa
     2581 tagaatgaac agtcaagaat taaaaaaacg tcaggagaac attcgtaatt tctctattat
     2641 tgcccacatt gatcatggta agtcgactct tgctgaccgg attttggaaa agacagaaac
     2701 ggtttcaagt cgtgaaatgc aggcacagct ccttgattca atggacttgg agcgggagcg
     2761 tgggattacc atcaagctaa atgcgattga gctgaattat aaggctaaga atggtcaaga
     2821 ttatattttt cacttgattg atacaccagg gcatgtggac tttacctatg aggtgtcccg
     2881 gtcactagct gcctgtgagg gtgctgtttt agtggtggat gctgctcagg ggattgaggc
     2941 acagacccta gcaaatgtct atctggcgct tgataatgat ttggaaattc ttccagtgat
     3001 caacaagatc gatttgccag cagctgatcc tgagcgggtt cgtcaggaaa ttgaggacgt
     3061 gattggtcta gatgcttcgg aggctgtact tgcctctgca aagtctggga ttggtattga
     3121 agatatttta gagcaaattg ttgaaaaggt tcccgcaccg tctggtgatg ttgatcaacc
     3181 gctgcaggcc ttgatttttg attcggttta tgatgcttat cgtggggtta tcctgcaggt
     3241 gcgtgttgtc aatggtatgg tcaagccagg tgatacgatc caaatgatgt caaatggaaa
     3301 aacctttgat gtgactgagg tggggatttt tacccctaag gctattggta gggattttct
     3361 tgctactggt gatgttggct atattgcggc ctcaatcaag acagttgctg atacgcgtgt
     3421 cggtgatacg gtcactctgg ctacaaatcc tgcagcagag cccttgcatg gctacaagca
     3481 gatgaatcca atggtgtttg cagggattta cccgattgag tctaacaaat acaatgatct
     3541 tcgtgaggcc ttagaaaagc ttcagcttaa tgacgctagc ttacagtttg agcctgaaac
     3601 ctcgcaagca ttgggctttg gttttcgttg tggctttctt gggctgttgc acatggatgt
     3661 cattcaagag cgtttggagc gtgaattcaa cattgatttg atcatgacag ctccgtctgt
     3721 tgtctatcat gttaatataa ctgatggtga catgcttgag gtctctaacc cgtcagaatt
     3781 tcctgatcca actaaggtag atagtattga ggagccttat gtcaaagccc agatcatggt
     3841 gccgcaggag tttgttggtg ctgttatgga gttggcccag cgtaagcgtg gagattttgt
     3901 gacgatggat tatattgatg acaatcgtgt caatgtgatt taccatattc ccttagctga
     3961 aattgtgttt gacttctttg ataagctgaa atcatcaacg cgaggctatg ctagctttga
     4021 ctatgaaatt gctgaatacc gtcgctcgca gctggtgaaa atggatattt tgttgaatgg
     4081 tgataaggtt gacgctctta gctttattgt tcatagagca tttgcctatg agcgcggtaa
     4141 gctgattgtt gagaaattaa agaaaattat tcctcgtcag caatttgagg tgccgattca
     4201 agcggctatt ggtcaaaaga ttgtggctcg ctctgatatc aaggccttac gcaaaaacgt
     4261 tcttgctaaa tgctatggtg gcgatgtttc ccgtaagcgt aagttgcttg aaaagcaaaa
     4321 ggctggtaag aagcgtatga aggctattgg ctctgttgag gtgccgcagg aggccttctt
     4381 gagcgtccta tcaatggacg atgagagtaa gaaatagtga catgttaagt aaggagctgg
     4441 atcatgcgat ctggctctta tgcttgatgt ctcgataggc tagaaaatag ggcttgtgtc
     4501 atgataggct tgtatgtttg agatggtttg gaacataatg actctatcat atctgtagtg
     4561 gattgacaaa gagccgtaaa ccattgatat ttggatagtt aatttcgagt tattctgtag
     4621 tactctctta aggtctttca tatgagcttt tctaatgttg gtttggttgc ttttcatgat
     4681 aagtcatatg ggattttttt ggtatactga aaaaagccta tagcctctac agtggcgtct
     4741 ccctctacag agatgataga gccagagtga ttgttacgat ctggagatgt ggcgctaggc
     4801 attaatgcag gaggacttaa ccagattgct gttaggcttg aaatcttaag ctatattgat
     4861 tgtcagcttg atttagagaa gtctaagttt atggctcaca aatgctcggt ctttttgtta
     4921 caatagagtt aatcagttat ttttataagg agacagctat ggaatctaag gaagagcttc
     4981 gccagcgtat tggagatttg gcttttgagg tgactcagca tgcagcgacc gaaagagcct
     5041 ttacaggtca gtatgatgat ttttttgaga aggggattta tgttgatgtg gtgagcggag
     5101 aggtgctctt ttcctctttg gataaattca attctggctg cggctggcct gcattttcta
     5161 agccgattca gcatcgtatg gtaaccaatc accatgattc atcacatggc atgcggcgtg
     5221 ttgaggttaa aagccgcgag gctggctccc atttggggca tgtttttaat gatggcccta
     5281 aggaggcagg aggcttacgc tattgcatta actccgccgc gctgaaattt atcccctatg
     5341 atcaaatgga gcaagagggc tacgccgaat ggttagggat ttttgataag agctaggaat
     5401 tgctagcggc caatgaaaag gtagagctct tagccaatgc tagtggctaa atcaaagaaa
     5461 taaaaaggtg gctaaagtac atagaaaaaa gaggtaagca gattggcagg tggtcaatct
     5521 gctttttgtg aggagacttt cagcctgctt tgcgctaaaa agtatgaaac caataaacca
     5581 cctactatgc gggtgtgtgt cggtggttag cttaagtttt ttcagttcgg ttttacaagc
     5641 ttctctaaaa ggactataat agctaatgga aaaggagatt catatgctaa catctttaga
     5701 aaaattaccg ggcgttttac tgtgcttgct gttagcactg cctgcctggt atttgggaag
     5761 cttatttcct attattggag cgccagtttt tgctatttta ttgggaatgc tattggcgct
     5821 tgtctatcag aagcgtgact acactaaatc tggaatcgca ttgacgtcca aatatatttt
     5881 gcagctggct gtggttttct tgggctttgg cttaaacgtg acacaggttt tagtggttgg
     5941 cttgcaatcc ctgccgatta ttgtagtaac gattgtgact gccttgggca taagctattt
     6001 gttcaaaaga tggttaaggc taccagccaa gacagctatc ttagttggtg tgggctcgtc
     6061 tatttgtggt ggctctgcta ttgcagccac agctcctgtc attgatgcgc aggacgatga
     6121 cattgccaag gccatttcgg ttattttttt gtttaatatc ttggcggcct tgctatttcc
     6181 agctttgggt cagatgcttg gcttatcaaa tcatggcttt gctatttttg ctggaacagc
     6241 agtcaatgat acctcatctg taacagctac agcgacagcc tgggacgcta ttcaccagtc
     6301 taatacgcta gatggggcaa ccattgtcaa attaaccaga acgctggcta ttattcccat
     6361 aacacttggc ttatctattt accaaaccaa gagcaggcag gcacatacga cagagggttc
     6421 ctttagcctc agaaaggctt ttccgacctt tattgtcttt ttcttgctag cttccttgat
     6481 aaccaccttt gctgctagct taggtctgcc aatggcaatc tttcatcagc ttaagctact
     6541 ctcaaaattc tttatcgtta tggccatggc agcgatcgga cttaatacca atctagtgac
     6601 cttagtcaaa actggtggta aggccatttt gctgggtggg atttgctggc tagcgatcac
     6661 atcagttagc ttagcaatgc aggcagcttt ggggagctgg taactgatga gaatagctgg
     6721 tgatacgctg ctttatagga aaagcaaagc ccttgctgct cctaaaaaag cttgttagag
     6781 cagctcactt agctgttaag tgtggcttgg tggggtgtaa gtaggctcta tcagttagaa
     6841 aagccatcag aacaaacgct atcattaagc tgaagccggg gaaactcggc ttttacgtta
     6901 tgcagaattg tctacatatt gaataggatt atccatttta aaaacgtttt catttgatag
     6961 aatacaatta tagcttggtt attagggtaa acgagattga acttcttatc tggtttagct
     7021 taagtaaaaa agcagttgga ggaagcatga aacgtaaatt tttaattggt agtcatggga
     7081 gaatggccag tggattgaaa agctctattg acattttggc tggtagaggt caggaattac
     7141 aagtcattga cgcttatatt gatgatagtg attatactga gcaggtattg acctttatcg
     7201 aagatgtagc agctgacgag caggcactga tttttacaga tttattaggt ggcagtgtta
     7261 atcaaaaaat agtaactgcc ctaatggaca gtggcaagga aaatatcttt ttgatttcaa
     7321 atagtaatct tgcagccttg ctatcgttga tgtttttaaa gccagaagaa gagctgacaa
     7381 aagacgagat tgtagcaacg attaacgatt ctcaggtgca gctggtggat ctagctccag
     7441 cgacagccgc agaagatgac ttttttaatt gaggaggaaa aatgaaatga ttacacaaat
     7501 tcgtgttgac gacagattga ttcatggaca ggttgctgtt gtttggacca aggagcttaa
     7561 tgcccctttg cttgtggtgg ctaacgatga ggctgctaaa aatgagatta cacaaatgac
     7621 tctaaaaatg gcagttccta atggcatgaa attattgatt cgctctgttg aggactctat
     7681 caaggttttc aatgatccac gcgcagtgga taagcgtatt tttgtcattg tcagctcgat
     7741 taaggatgct tgccagattg caaagcaggt gaaggactta gaggctgtta acgttgcaaa
     7801 tgtagggcgc tttgacaagt cagacccagc aactaaggtc aaattggctt caagcctatt
     7861 gttaaatccg gctgaattag aagcagcaaa agagctggtt agcctgccta acctagatgt
     7921 tttcaatcag gtactgccat ctaatagcaa ggttagcctg agccagctca tcaaataaag
     7981 aaaggtgtaa tgactatgtt agtaccagca acaatggcag ccttagctgt attgatttgt
     8041 ttcgggggaa attatttaac tggccaaagc atgatggaaa gaccgcttgt ggttggtttg
     8101 gtgacaggat tgctcttagg agatatgaag gtcggtatct tgatgggagc gtcactagag
     8161 gcacttttcc taggaaatgt taacattggt ggtgtcattg cagcagagcc tgtaacagca
     8221 acagctatgg caacgacctt taccatcatt tcacatattg atcaaaaagc agctatgacg
     8281 ctagctgttc cgattggcat gctagcagcc tttgtggtca tgtttttgaa aaatgttttt
     8341 atgaatatct ttgcgccaat ggttgataag gcagcagcgg caaaccatca gggcaagctt
     8401 gtcatgctgc actatggcac atggattgtc tattatttga ttattgcctc tatttccttt
     8461 atcggtatcc tagttggaag cggacctgtt aacgcctttg ttgagcatat tccacaaaat
     8521 ctgatgaatg ggctaagtgc agctggtggt cttcttccag cagtcggatt tgccatgctg
     8581 atgaagctct tatggacaaa taagctagca gttttcttcc tattaggctt tgtgttgaca
     8641 gcttatttga agctaccagc agtagctgtg gctgcacttg gtgcagttat ctgtgtgatc
     8701 agctcgcagc gtgatttaga gttagatgct attactaagg gagctatcag taaccaaagc
     8761 agctttgact ctaaagaatc agaagaggag gacttctttg catgagatct caagacaatt
     8821 taactaaaga agaaagaaaa atgctacgct ctgttttctg gcgttcatgg accatgaatg
     8881 ctagtcgtac aggagctacg caataccacg ctgttggggt tatctatacc ttgttgcctg
     8941 ttatcaatct cttttataag acagataagg ataaggcaga cgctcttgtt cgtcacacca
     9001 cttggtttaa tgcgaccatg catattaata actttatcat gggcttggtt gcctcaatgg
     9061 aaaagaaaaa cagtgaggat ccaacctttg acgctagtgc tattacagcg gtcaaggctt
     9121 ccttgatggg acctatttct ggtgttggag attccttttt ctggggtatt ttgagggtca
     9181 ttgcagctgg tattgggatt tcacttgcta gcacaggctc agcgatggga gcagtagtct
     9241 ttttacttct ctataatatt cctgctttta tcattcatta ttatagcctt tatggtggct
     9301 attctgttgg tgctggcttt attaaaaagc tttatgagtc tggtggtatt aagattgtga
     9361 ccaagacctc aagcatgctt gggtcaatga tggttggctc catgacagct tcaaatgtga
     9421 agtttaagac cattttaaca gttgctgcaa agggagccaa ggaagcagcc tctatccaaa
     9481 attatttgga tcagctcttt attggagttg tccctctttt agtaaccatg accgcctttt
     9541 ggcttttgcg taagaaggtg aacattaact ggattatgtt tggcattatg ctattgggta
     9601 ttgttcttgg tcttttaggt atttgctaat aatctcctag catcaaggat aggtaaggca
     9661 gggacttctt gctttgctta tccttttttg tagtgagggc tgctgaaata gccacctgct
     9721 tgcttaaatg gcttatggat ttgttagata gattaagatt ttcttagctt tgagaaatga
     9781 tttggtataa tagaaggaaa taagggaaaa ggctgcctat ggaagaaaga tttaaaaagc
     9841 gattgcagga tgatatttca catcattttt cacaccaatc attgattttg tccattttac
     9901 tgattggact ctttctcatt ttttcattgg cacctcagca aattgggctg tatcaagatt
     9961 tgaaggctgt tgaacatagc tatcaccagc tgattcggca aaataaggcg cttttaacgg
    10021 agctcaatca gcatattctg accaaatttg tgaatcatca gctgagctct tctgacctta
    10081 gcaaacaata ttatcaccta agaaaccgct cacaaagcca atcagagctg ctggtttttg
    10141 atgctaacag tcacatgctg tttgctagta atcagcatct gggaaatttt tttcgcaatg
    10201 ctgtctatat gacagaagtc ttaaaaaaag caaggcaaag gagtagcttc ttgaggatca
    10261 gtatggataa tgaggagggg cattatttac tgctgataaa gcctattaag atagatcatc
    10321 aggttaaggg ctattcgctt cttgtgatga atggtaagga ttttcttcag ctatcacatc
    10381 agattgcttc agattttgtg attgcagatc agtttgacaa tagctttgcc tttaccaatc
    10441 ggacctttat gacctcaagt ctgaataagc ttgacagtca ttttcttaag ggctatttta
    10501 tctttcacga gcatcgtgcc tttatcctaa gaaaggtcgc tcttagtcct tctatcactc
    10561 tttacagcta ccgccctttg attccagttt ctattgcact cttgttttca ttgatgtcct
    10621 ctgtcatgat ttatgctatt ttgtattgga agtctaaggc tctggcgacg cagattgctt
    10681 ctagcaattc agcagcgatc aatcagatga ttcttgatat gcaggccatc tcaaggcagg
    10741 aaaaaaatgc cattgacctg caaagtcaag atgaatttca atacctgtcg gttcagatca
    10801 atcagatgat tagccgattg caggcacttc atcagaagac cctagcctta gaaaagcaaa
    10861 atgtgagttt tgaaaaacgc atgctggaag cccaatttaa ccctcatttt ctctataata
    10921 cacttgaaac aattttgatt acaagtcatt atgacagtga cctcacagaa aaaattgtcc
    10981 ttcagctaac caggctgctt cgctatagct tagacgaatc acaggaggct gtgtgtctgg
    11041 gagaggattt ggctgtctta gaatcctatc tgttgattag ccagattagg tttgaagagc
    11101 tgcgctacac gatagctgtt gaaccagccc tagagaccct aagggttccc aaattatttt
    11161 tattgccatt gattgaaaat gcgatcaaat atggtctgcg ctatcgccat gaccttgtga
    11221 ttgagatcag cgtgagacag cttgctgatg gaatttactt tactgtagca gataacggtc
    11281 ctggaattag tcaaaaaagg caggccgata ttaaagagct cttgcattca gaggattcac
    11341 atcatggctt ggtcaattct tatcgtcgac tcaagcatca atttataaaa gttgaattga
    11401 tcttttgtca aagagatgag cgctttttac taacctatat ggttaaggag taacagatgt
    11461 ataagctact aattgttgaa gatgagcata ttattcgcaa atggcttcgt tatgcgattg
    11521 attatcatgc gctcaatatc cttgttatcg gagaagctaa ggacggtcag cagggggcta
    11581 agctgattgc agaggctaag ccagatattg ttttgacaga cattaacatg ccgattatga
    11641 ctgcctttga gatgtttgag gccacaaaag agcagtccta tgctaaaatc attttgtctg
    11701 gctatgctga tttcgctaat gcaaagtctg ctatccatta tggtgtgctt gagtttttga
    11761 ccaagccctt ggaaaggcag gccttacatg attgcttgct aactattatc caaaagctgc
    11821 aacagcagtc tcaagagcag gagctaagcc agcagcagga ttacctcaaa ctgccacagc
    11881 ctaatgacca attgcctgat gttgtccaag aaatgctcag ctggatccat gagcattacc
    11941 aggataaaat catgattggt cagttggctc acgatctggg ctatagcgaa agtcacctct
    12001 atcatttagc taaaaaatac ctgaaaatga cttttagtga ctatatcaac caataccgcc
    12061 tgaatcgagc aattcaattg ctgattgctg agccggatgt gatggtttat cagcttgcag
    12121 aggctgttgg catttatgac taccgctatt ttgatcgtgt gttcaaaaaa tatttaggac
    12181 aaacggtcaa ggatttcaga gaaacggtat tacaccagag atcagatagg agttcattgt
    12241 gacaagaaaa aagctgctat tagcaatggc aatagtgata ctaggtgtga ttggctctgg
    12301 cttgtatgct atctggaggc atcaagcagg accagctccc agcaaaccaa gagaattggt
    12361 tgttttgaca cccaacagtc aaaatatcct aacaggtacg atcccagcct ttgaagaaaa
    12421 atacggcatt aaaatccgtc tgattcaagg aggcacaggc cagctcattg atcgcttgca
    12481 aaaggacaag gaccagctcc atgcagacat cttttttggg gggaattaca cacaatttga
    12541 gagtcataag gagctatttg agccttacct ttcaaagcat attggctttg tattgcctga
    12601 ttacctgctg caaagcgagg tcgcaacccc ctatacgctt aatggaagtg ttctcattgt
    12661 gaataatgaa ttggcaaagg acatggttat taccagctat gaggatttgc taaagccaga
    12721 gctaaaggga aagattgctt ttgcagaccc caacacctcc tctagtgcct tttctcagct
    12781 gaccaatatt ctcttagcca aggggggcta cactaacccc aaggcttgga gctatatcaa
    12841 gcagttgatt catagcatga attcaatcaa atctgctagc tcatcagatg tttatcagtc
    12901 agtagcagaa ggaaagatga ccgtcggtct tacctatgag gacccctgtg ttaacctttt
    12961 aaagagtggt gccaacgttt ctattgtgta tccaaaggag ggaacggttt ttttaccctc
    13021 agcagttgcc attgttaagc aatctaaggc caaggctgat gccaaattgt ttattaatta
    13081 tatgttgtct ttagatgtgc agcgggcctt tggtcaatca accagtaata ggccaattcg
    13141 aaaggacgct aaggccagtc aagacatgaa gcctttagat gacattatca cgctaaagga
    13201 agactatgat tatatcacaa gacataaaaa ggatatttta gaacgataca atcaattgag
    13261 aaagaccact gactaaatgg ctttgttata tgaaacagtt catgctgtgc tgcacctgaa
    13321 tcgttagctg ctttgtctag ctttttgagg tcaatctctg cttgggctgt tttttatgtt
    13381 accataaccc actgcatttg tttagaaagt caagcgagat cttaatagcc agttataata
    13441 ggtctttgag agggagtctg agcttgcttg aggtggcaag aagatctgtt ttgacgtcaa
    13501 atggctgaat ttttggtaaa atgatagcat gaatgaactg ataaaacaca agctagagct
    13561 tttgccagat agtcctggct gttatttgca taaggataag gctggcacta ttatttatgt
    13621 tggcaaggcc aaaaatctga gaaatcgcgt acgctcttat tttcgaggaa gccatgatac
    13681 caagacagag ctgttagttt ctgaaatagc tgattttgag tttattgtca caggatcaaa
    13741 tacagaagca ctcttattgg aaatcaattt gattcaagag aacatgccca agtacaatat
    13801 caagctaaag gacgacaagt cttatccctt tatcaagatc actaacgagc catttccaag
    13861 actattaatc acacgtcaga ttaaaaaaaa tgacggcctg tattttggtc cctacccaga
    13921 tgcttacact gccactgagg ttaaaaagct gctagaccgt atttttccct ttaaaaaatg
    13981 caaaaaccct gttaacaagg tctgctttta ctatcattta gggcaatgtc aggctcacac
    14041 gatttgccat acagacaagg cttattggga cagcttggtt gctgatgtca agcagttttt
    14101 aaacggtaag gacgacaaga tcattgatga tttgcgctcc aagatgcttg aagcttcgca
    14161 caatcaagaa tttgaacggg cagctgaata tcgtgatttg atttcaggta ttgccaccat
    14221 gcgaaccaag caaagggtga tgagtaagga cttgcaggat agggatattt ttggctattt
    14281 tgttgataag ggctggatgt gtgtgcaggt cttttttgtc cgtcagggta agctcattca
    14341 gcgagatgtg aatatgtttc cttattacaa cgaagctgaa gaggattttt tgacctatgt
    14401 cgggcaattt tatagcgacc aacggcattt gatccctaag gaggtcttta ttccagagac
    14461 gattgatgag accttggttg cagccattgt tccagcaagg attgtcaagc cgcagcgagg
    14521 ggaaaaaaag cagctggtcg ccttagcaac taagaatgct cgggttagcc ttcagcaaaa
    14581 atttgatttg ctggaaaagg atttaagaaa aacaagtggt gctattgagc atcttggtca
    14641 gctgttaggc attgaaaagc ctgttcgtat tgaggccttt gacaattcaa acattcaggg
    14701 cacaagtccg gtagctgcga tggtggtttt tgtcgatggg aagcccagca agaaggacta
    14761 tcgcaaattt aaaatcaaaa cagtgattgg tccagatgat tatgcgagca tgagagaggt
    14821 gatttatcgt cgttatagcc gcgtgaagca tgaagggcta caggcacctg atttgattat
    14881 tgttgatggt gggcagggtc aggtcaaggc tgctcgtgat gtgattgagc accagctagg
    14941 ccttagcatt ccagtagctg gtctgcaaaa aaatgacaag caccagaccc atgaattgct
    15001 ttttggtaac cccttggcag tggttgagct gccgagaaat tcagaagagt tttttctgct
    15061 gcatcgtata caagatgagg ttcatcgctt tgccattacc tttcacaggc aggtcaggag
    15121 taaaaatgcc ttttcatcaa agctagatca cattgcaggc ttagggccaa aacgcaaaca
    15181 gctactactc aagcgattta aaagcatgac tgctcttgaa caggctagtc ttgaagaaat
    15241 tcagcagcta gggattccaa aaacagtcgc tgaggcactg tttgatcacc ttacctcaaa
    15301 aagtgaggtc tgaattggcc ttgtcaggag ctcaagcagt ctgaattttc ttgacaaaag
    15361 tgaaaaaata gctgaaacca gtttcaaaaa atgatagaat gatactacaa cataaaagaa
    15421 ttagatagga agcatttgca gtgaaatttc tcgaattaaa caaaaaacgc catgctatta
    15481 aacggtttaa cgataagccc gttgattata atgacttgcg aacagctatt gaggttgcca
    15541 ctctggcacc aagtgctaac aatattcagc cttggaaatt tgtcattgtt gaggaaaaaa
    15601 aggcagagct ggcaaaggat ctgccgttgg ctaataagac tcaggtagag caggctcagt
    15661 atgttattgc cctgttttct gataccgacc tcattcagcg ctctcgtaag attgcccgca
    15721 ttggggtcaa gtccttgcct gataacttga ttggttatta catggagacc ctgccgccac
    15781 gttttgctac ctttactgag acccaaaaag gcgaatatct ggccattaat gctggcttgg
    15841 tggcgatgaa tttggtcctt gccttaacgg atcagaaaat ggcctcaaat attattttag
    15901 gctttaataa aaagctaact aatgagattt tagatattga tccacgcttt cgtcctgaat
    15961 tattgataac tgtggggtat agcgatgaca agccagagcc tagctatcgc ctaccagtag
    16021 acgaaatcat tgaaagacgc taagatacac aactactcgt ccagctagcc tataagtttt
    16081 tggatttagg aggatagcga ggcaacacat aaaggagaaa aagatgacaa caattgattt
    16141 taaagcagag gttgataagc gcaaggaagc tatgctagag gatctatcaa acctattaag
    16201 cattaattcc gagcgagacg atgctaaggc agatgccaag cacccatttg gtcctggtcc
    16261 ggttaaggcc ttggagttct ttcttgccat ggcagagcgt gatggttacc aaacgcgtaa
    16321 tattgataac tatgctggtg attttgaatt tggtcaggga gatgaggttt tagggatttt
    16381 tgcccattta gacgtggtac ctgctggtag tggctgggag acagaccctt ataagccggt
    16441 gattaaggat aatcgtatct atgcgcgtgg ttcatctgat gataaggggc caaccatggc
    16501 ttgctattat gccctgaaaa tcatcaagga attaggcttg ccagtttcta aaagggttcg
    16561 cttcattgtt gggactgatg aggagtcagg ctggggtgat atggactatt attttgctca
    16621 caatggcttg aagaaccctg attttggttt ttcaccagat gctgaatttc ccattatcaa
    16681 tggtgagaaa ggaaacatta cagaatacct tcattttgtt ggtcaaaatg ctggagcttt
    16741 tgtccttcat cgcttccaag gcggtttacg tgaaaatatg gttcctgaat cagcgacagc
    16801 tctgatcagc tcaccgcatg agcttaatgt tatcgaagct tctttggagc aattcttatc
    16861 tgagcacgca gtgacaggat ctgtcaaaga ggctgatggg ctattggaag tgaccattat
    16921 tgggaaatct gctcatggct ctacaccaga ggctggtgtt aacggtgcaa ccctgctggc
    16981 taaattctta aatcaattta gctttgatgg cgcagccaag gcttatttgc atattgcagg
    17041 tgaggtgctt catgaggatt tcacagcaga aaagcttggc ttggcttata cagatgacaa
    17101 aatgggtgcc cttagcatga atgcaggtgt ctttagcttt gctaaggatt cagatgacaa
    17161 taccattgcc ttgaatttcc gttatccaaa gggaaccaat gcagcagtgc taaaggcagg
    17221 gcttgagcaa ttaccaggct tgactaaggt taccttatct gagcatgaac acatccctca
    17281 ctatgtgcca atggacgatg agctggtctc aaccctccta tccgtctatg aaaagcaaac
    17341 aggactcaag ggctacgagc aggttatcgg tggtggcacc tttggacgct tgcttgagcg
    17401 tggtgttgcc tttggtgcga tgttcccagg tgatgaaaac acaatgcatc aggccaatga
    17461 atacatgcca ttagacaata tttaccgatc agctgccatt tacgccgaag ctatttatga
    17521 attgatcaaa taagagattg aacaagctct ctgtctaaga tgagccttgc taatattaac
    17581 gaataaaagc cttatgaagt tagtcgttta atgagacttc ataaggcttt ttgtttggcg
    17641 tcaagccatt atttacaaag agaaatgcca cagtggatca tcttttgaaa agtccttgta
    17701 aaaacagacg taaaactagt tttagaggag acattgatag gcagtcatgc ttatcaagag
    17761 atcttgtcta gcagttatgg caaaaagatc agtgaactat tattttccaa ggcagaactg
    17821 actgaacaat tgagtaatta attcatcagg tgcggcatcg cctgtgattt ctcctaggat
    17881 ttcccaagct ctggtcaaat caatctgtaa gagatcaacc ggcattccta aagcaagtcc
    17941 ttcattgaca gcctctaagc tttgtactgc ctgctcaatc aaggaaatat gacgagcatt
    18001 ggataggtaa gtcgcatctt gctctattag cccagtatga tcaaagaaaa tctgattgat
    18061 ccggtcttcg atcaggtcaa tgttttggtt ttgcaaaact gatattggga tcgcctcttc
    18121 tggaagctgg tctttttcaa tgacctgctc cagatcggtt ttattgagga gaataatgcg
    18181 attgctatcc tgactaaggg ctagcagagc cttgtcctgt tcggtcagct tttccgaagc
    18241 attgagaact aaaaggacca gatcagcctc ctgtagggct tttttagacc gctcaacacc
    18301 aatttgctct actaaatcat ctgtttctct aattccagca gtatcaacta gctttagagg
    18361 aattcccttg atattgacat attcttcaat gacatcacga gttgttcctg caatatcagt
    18421 gacaatggcc ttatcctcac gtaacaaggt attgagcaga ctagactttc ctacattcgg
    18481 tcggccgata atagctgttg acaagccctc acgtaggatc ttcccgcgct tggcagtacg
    18541 taggagctgc tctaaaagtg tttgaaattc tcgcgttttg tcacgcaaaa gagcagtggt
    18601 catttcttcg acatcatcat attcggggta gtcgatacta acctcaacct gggctaaggt
    18661 atttaggatt tcttgacgtg tgtcgctgat gagctgtgat agggagccgt ctagctgctt
    18721 gatagcaata gacatggcct tatcagtctt tgcacgaatc agatccatga ctgcctcagc
    18781 ctgtgttaaa tcaatacggc catttaaaaa agcacgcttt gtaaattcgc cgggctctgc
    18841 cattcgagct ccctgtttaa tgaggagctg taaaatgtca tttgtcaccg caataccgcc
    18901 atgggtattg atttcaatca cgtcctctct ggtaaaggtt tttggcgcca gcatgactga
    18961 taccatgacc tcatcaatca cttcacctgt gcttggcttg ataatatgac catagttaag
    19021 ggtatgtgag gcgactgttg ttagatcttt tcctttaaag atcgatttag caatgtccag
    19081 agccttggta ccagacaagc gaacaatgcc aatagctcct tcacctaacg gagttgaaat
    19141 ggctgcaatt gtatcaaatt ctttagttat actcatgcct tctattgtag aacaagtcag
    19201 catagaaagc aaggtattgc attagctgct cgttgtcgtc attcttgtct agtggcaaag
    19261 cctcaaaagc agttgtaaac agctaaagct atgattaaaa agccttgtat ggtaagtaca
    19321 ggataaagcc aaaaagctga tgagttttag ataaacatac aggctcgaaa agccctatta
    19381 aaccgacagc aacaatcctc acacagtata gttgacttaa ctacctgatg tcatttctgg
    19441 ctgtttttat aatgacaatg gcaatatcgg ttattttgac tatgctgggt gcttgtatcc
    19501 tagtggactg actgacaatc agggcttctt tttcaaccac gaaaacatta aaaaagtctg
    19561 gtttggaggc tatattgacg atagtgaaag agaagctcaa gactttttta aaaaagaggc
    19621 aggctatatt aaatatccta aacttagtat agataatagc actagatagc attaatttaa
    19681 gtatataacg ttatgattat ggttggatta gttcattata cactagcaat aaggtagatt
    19741 attttgttat aataaaatat atacaattat tagagagtta gaaagagtta tatggtagta
    19801 ttacaaaata atagtagcac agctagtgag cgagcgacag ctttggcaag aggagtccag
    19861 gccctctcta gtgctggtgc ggtgagcaaa gatatgaaga cgaccgttac tggaaatcgt
    19921 agtgatgcca gctctgccat tgatttatcg cacaacgttt cagcgcaggt agttgggatc
    19981 atcgcttcta tgtcgcaaca cattcagagt gtctctgcct cttttcaagc gatggatctt
    20041 cagcttggaa aagagttagg gcgtttagaa aacaggcgga ggtttagtct caatgaccca
    20101 aaatgagctc atgtaccaga aggagagatt ggataaacgc ttggaaacca tagcccaaga
    20161 gcttaagcgt aatgaacagc gctttgaaga ctatgaggaa ctatctaacc tagcggcaca
    20221 actgttaaca gcagctgcaa ccacctttcg ttcatcatca gatagtcatc tctttgaagg
    20281 ggctttggca gaagaatgtt atttgaaaag gaaaacacaa gcgtccttgg aacaaagtca
    20341 tgaggagctc ttaggagagc agcgtcgttt gtaccaagaa gaggaagccc ttacccgaca
    20401 attaaagcta gtcaaaggaa aggagagagc taatgagcat tgacatgtat ctggggtcat
    20461 cggaccagca agctagtagc gttggtaagg tcttgcagca gcggataaca gcttataagt
    20521 ctttgcaaag agctttggag caattggtgt cttctagtcc tgacttatca gggcatacct
    20581 atgcttctgc taaaaggtac agcgagcagg tattgatccc tttgatgagg ggctgtatcc
    20641 tgctagatga agccatcaag gaagcctgtg cagcatttcc taatgactac cgtcgtcagg
    20701 ttgatagtgt ggatttgaag gagagtgagc tggtggatca gatcagccgc tcagaccgca
    20761 tcataggtcg ttacgttgag ttgattgatc tggagtatcg gcaggagctg ccgaattact
    20821 cttatattac taatctcaag agcggagcga gtaaccagcg tcaagtcaag agaaaattag
    20881 aagagaagct ccttaagctg cgagagtttg atagcaattc ccgtcacctc ttttcgtcta
    20941 tcgcagcctt agccgaggca gtcaatatag gtatcagaca aaccaagacc tcttggaatg
    21001 ggacaagtca gacgttcact cttcccaggg ctcttgactt agagtggacc aaggtagtag
    21061 aaaagaggtg gacgcaaagg gaggaaaaag cctcgaagct gaagctacag caggcagcag
    21121 aaaaactttc gagagaaacc gggattaagt acgaagatgc ctatcgtttt gtgatggacg
    21181 gtgttctgtc agatgaaaat aagaacaaaa tcaagagtgt aaagaaacta gttaagtata
    21241 caaagggtgg gctgtatatc gtttcctcag gaaggtatta ttggaaacat tcaggtaaac
    21301 attattggaa aaatacacca aacaaaacat ggaatatttg gaaagcatct aaaaacgatc
    21361 ccaattttga caaaggaggg atcaaaggta aacatttttc taaaaaagga gcccgttaca
    21421 cagacttacc tggtatcaag caattgaaga agagtgaaac agtacaatcc ctcatttcaa
    21481 aaatttcaaa agataatcaa gggaagctca ccaaagttgg taaagggtta aagaaagttg
    21541 ataaagagct aagcaacata tcgtcaaaac tcaagtcata tgagcatgga cgcctaaata
    21601 gagacttgaa aatgatgaag gagaataacc tgggtaaaag tctcggtaag tttgggaaag
    21661 ttggaaaagc tgcaagcaag gtgctcaagt ttgcaggaaa aggtctcaaa gttgcgggtt
    21721 gggtaggtgc tgctataaat gttaaggact cggttgaaac ttacaagaaa aaaggctata
    21781 gcaatgagca aactgctgct ttaacagccc gtaaggtagc tgttgatact gcaacaactg
    21841 ttgtcggaag caatattggg cgtgtaacag gtgcagttat tggtcaagca gttataccta
    21901 ttccaggtgt aggtgctgct atcggttctg ttgcaggaag tattttagga gctatggcag
    21961 gtagttggat tggtagtaca attaatgaca atttagataa gaacgtaaaa cctaaacaat
    22021 caggaaggag tttagcatgg taatgttaat gagaacactg ttatttccag ttgataacgg
    22081 acttgattca ggattgactg gtgatggtta tgcagctgag tatgatttgt ggactggaaa
    22141 ggtcacgtgg cgacaacttg gtgatggaaa aataaaaagg caacaaaagg tagcagctat
    22201 aattaatctc attgcagctg caatatctcc acttgtcatc atgtctatca tttttacggc
    22261 aaaaagtctg aagctttttg atgtagatac tagtacaaca atttatcgat atgctcctct
    22321 gatggtaggc ttggtctttt tcttctcgtt tgaattattg atgctggcta ttagacgtct
    22381 gtatccatta gccaaagagg agccaagttt aaagcgtcaa catgggtatt ttaagaccat
    22441 gtatgacaat actatacgtg agaatgatgg tgtttttaat aatttatcag taccttttat
    22501 agggctttat gtagctttct tgattgcctt ttcggttatt ccaatttttt actctcaata
    22561 tctgcagcaa aattcttttt ggtcctattt aggaaattta gtaggaagta gcattcttat
    22621 ttccttagtc cccaattttt tatggaatgt cttagtgaaa caattgattt acatcaagct
    22681 tattcgcaaa acgaaagaaa aaatcttaaa gaatgaaacc taaacaatca ggaaggagtt
    22741 tagcatggta atgttaatga gaaccttgtt atttcccata gataatggta tggataataa
    22801 cttaattgga gacggcttat cagctgagta tgacctatgg actggaaaag ttacgtggcg
    22861 tcagcccagt gatgataaga ttagaaccca acaaaaggta gcatttgtac ttaatcttat
    22921 agctggtagt ttatctccat tagctatatt tttatttgtt attattgtta gacgcttagg
    22981 cgtttttagt ggcgatacta attcaatgat tttcaagtgg gcaccgctaa tagttggatt
    23041 tatccttttt atatcgtttg aattattgat gttggcgctt agaagtagat atacgatatt
    23101 agagaaagag cccgatttag atcgtcaact atactattat cgtacaatgt atgataatac
    23161 tatacatgac aattcaggtg tttttaacaa tttatcagta ccttatgtag gtctatacat
    23221 tactttattt ctaatttttt taatcattcc actttgttat catttttact tgcacccatc
    23281 ttcatttggg gattatctcg ctgcattatc tgtaacaagt ttgttgattt ccttatttcc
    23341 caatttttta tggaatggtg tcttgaagca cgttatatat gtcaaactta ttcgccaaac
    23401 aaaagaaaga attttaaaga atgaaaccta aacaatcagg aaggagctta gcatggtaat
    23461 gttaatgaga acgctgttat tcccagttga taatggcatg ggaacgggct tgaccggtga
    23521 tggttatgcg gctgagtatg atctatggac tggaaaggtc acgtggcgac aagccaccaa
    23581 acaaacaatt gaaaagcaac aagcactaac gtctaacctt ttgattattg cctcatgctt
    23641 atcaccagtt actgttgcag gaatgatact gttgagtaga agtttcccta ttttcgagga
    23701 agacttatca gagaaaattg atacttatgc tccaattatt cttggtgttg tgttatttct
    23761 tgcttttgag acgttaatgc ttgctatcag aggtcgtgat ccattagcgg agaaggaacc
    23821 agatttaaag cggcagcatg actattttga aaagatgttt gattttgcta ttcgtagaaa
    23881 tttgtcgtca gataatctaa aaactcctta tatagctact tattttgctt ttggtatttc
    23941 tttactctgt attccattta gctattatgt ttatctgaat ccggagcaat tccctaattt
    24001 ggattatggt catttatcaa tcctgcttgt aacaagtatt cttatttccc tagttcccaa
    24061 ctttttatgg aatgttctat taaagcacat tatctatatc aagcttattc gcaaaacgaa
    24121 aggacaataa aacattatga acaaaccaga acacatttta ccgattggta ctatagtgct
    24181 gacggagaca ggagaaattc ctttgatgat tgtgagtcgt gcctctcttt ttgatgataa
    24241 tggagaaatc ggctattttg attatgctgc agttccttat ccagaaggca taggaaatga
    24301 taatgagtac cttttcttca accatgagga tattgctgat gtcatctatt ttgggtatgt
    24361 caattccaat gaacagcttt ttgcagaagc ctacgatgat ttggtgaaaa catcaggtta
    24421 tcgtaaatta agcttagatc accatcaata gaaaaaggac atgaagatta tctagaaaaa
    24481 gaaaagaact aatgagcatt gacatgtatc tggggtcatc gaaccagcag gctaatgatg
    24541 tatggccaat attttgagag gatcggcctg ctcctctttt ttgtatgttc aaagctataa
    24601 aaagcttact ttttgaggta taaagcttcg acaatcaaga gtatttgctc tggtggcttt
    24661 aatgatcttg cttatagctt ctggtcagat tgttttagcc tgcttgtgct gtctgatcca
    24721 gatttgactg aggctttgat gacagtcgtg aaggcgggtt taagaatggc atgtctaatg
    24781 tcaatttaca atagagaagg aaaattgatc aaacagtgtg agatattatt aacaagtttg
    24841 cgctttcatg gtataataaa gtgctaggaa gcattttatt ataagataag ggggaatcat
    24901 ggaagcactg aaaaagattg ccggtgtgac tgctgcgcaa tatgtaacag atggaatgac
    24961 cattggatta ggaacaggat caacagctta ttactttgtt gaagaaattg gtcgtcgcat
    25021 caaggaagag ggactacagg ttgttggtgt gacaacctca agtgtaacaa ccaagcaagc
    25081 agagggccta ggtattccct taacatcaat tgatgatatt gactgcattg acctgactgt
    25141 tgatggtgct gatgaggtgg ataaggcctt taacggtatt aagggtggtg gagcagctct
    25201 attgatggag aaaattgttg caacaccaac caaggaatac atctgggttg ttgatgaatc
    25261 aaagctggtg gatcatttag gtgctttcaa gctccctgtt gaggtcgttc aatacggtgc
    25321 tgataggcta tttcgagtct ttgaaagggc tggctataag ccctcttttc gcatgaaggg
    25381 ggataagcgt ctcataacgg atatgcagaa ctttatcatt gatcttaacc ttggctgtat
    25441 cgaaaatcct tgtgagtttg ggcgtctgct ggatcaaact gttggtgttg tcgagcatgg
    25501 ccttttcaat ggtatggttg ataaggtcat tgttgctggt caggctggtg taacggtcct
    25561 tgaagctaat cagtcaacct aattcctagc tcaatcatgt tttacattat tttataggtt
    25621 ttggggagcc aaccgtaacc tcccctagat tggagactta tgtcaaaatt taatcgtatt
    25681 cacttagtcg ttctagattc tgttggtatt ggtgcagcac cagatgccga caaattcttt
    25741 aatgctggtg tagctgatac agattctgac accctcggtc atatttcaga gacagctggt
    25801 ctggctgttc caaatatggc aaaaattgga cttggtcata ttcctcgtcc tgtcccccta
    25861 aagacagttc cagctgaggc tgatcctact ggctatgtca ccaaattaga agaggtatct
    25921 cttggtaagg ataccatgac aggtcactgg gaaattatgg gcttaaacat tactgagcca
    25981 tttgatacct tctgggatgg ctttccagag gagattatcc aaaaaatcga agctttttca
    26041 ggccgtaagg tcattcgtga agccaataag ccttactcag ggacaaaggt gattgatgat
    26101 tttggtcccc gtcaaatgga aactggtgag ctgattgttt atacctctgc cgaccctgta
    26161 ttgcaaattg cagcacatga ggaggtgatt cctgttgagg agctttaccg gatttgtgag
    26221 tatgcgcgtt ccattaccct tgagcgtcct gctcttttag gtcgtattat tgcccgtccg
    26281 tatataggag agccaggcag cttcactcgc acagctaatc gtcgtgatta tgcagtctca
    26341 ccgttccaag acactgtctt aaataagctg gctgacgctg ggatttctac ttatgctgtt
    26401 gggaaaatca atgacatctt taatggctca gggattacca acgatatggg gcacaataag
    26461 tctaacagtc atgggattga taccctgatc aaaaccttgc agttgccagc atttacaaaa
    26521 ggtctttctt ttactaactt ggttgatttt gatgctagct ttggtcaccg tcgtgatcca
    26581 gagggctatc gtgactgttt gcatgaattt gatcgtcgcc tgccagagat cattgccaac
    26641 atgaaggacg atgatctgct cttgattaca gctgatcatg gcaatgaccc aacctatgct
    26701 ggaactgacc acacacgtga gtatattcca ttgcttgctt actcagcctc ctgcactgga
    26761 gcaggtgtga ttccacaggg acattttgct gatatttcag cgactattgc cgaaaacttc
    26821 ggtgtggaca ctgctatgat tggaacatca ttcttagctg acttggtata ggagtaagca
    26881 aatatcattt gataggccaa ggagcttggc gtatcaaatt gaaaaccagc gctgtggtta
    26941 ggtctattaa taggcttgtg gcaggttgtc tagttctgat gatcggtgtg atattagttg
    27001 atttattgga ctttgctaca gcaaaaagct caagagaagt atgctttata gtaaaaaata
    27061 aataagataa agggagaaat aagatgacat tacttgaaaa aattcgtgaa acacaggctt
    27121 tcctagaaag caagggcatt gataagcctg aatttggtct cattttaggc tctggtctag
    27181 gtgagcttgc caatgaggtt gagcaggcga ttgtgattga ttatgctgat attccaaact
    27241 ggggcaaatc aacagttgtt ggtcatgctg gaaaattagt ttatggtgag ctggctggtc
    27301 gtaaagtatt ggcacttcaa gggcgctttc atttctatga aggtaatcca atggaggttg
    27361 tgaccttccc ggtacgtgtg atgaaggctc tgggctgcca tagcttgctg gtgacaaatg
    27421 cagcaggcgg tatcggctat ggtcctggga cgcttatgct aatcaatgac catattaata
    27481 tgacaggaac aaacccgctc attggtgaaa acctagatga atttggccca cgcttcccag
    27541 atatgtctga tgcctataca gcagcttatc gtgagacagc tcgctcagta gcagaaaaac
    27601 taggcttaga cctgcaagag ggtgtttacc ttggctgttc aggaccaacc tatgaaacac
    27661 cagctgagat tcgtgccttt aaggttatgg gagcagatgc tgttggtatg tcaactgttc
    27721 cagaggttat tatcgctgcc cactcaggct tgaaggtgct tggaatttca gcgattacaa
    27781 actttgcagc gggcttccaa tcagagctta accatgaaga ggttgtagag gtaactgagc
    27841 gtatcaagga aaactttaaa ggcttggtta aggctatttt ggcagagctt taaggcttgc
    27901 tcttagacta gcagtaacca tgagcgactg ctagtacttt gatcgataag acgaggaaaa
    27961 ataaggattg ggacattaga gtgatgactg atatggaaca tacgataagt attcttttag
    28021 aagtttatgc ttatagtcat gcctacaaaa ttgcaagaac tctgcctgat ttttccccca
    28081 aggtacttta tttgcttgag cttttaaagg aaagaagaga gcttaacgtt gcttatgcct
    28141 ttcaacatag ggcggaaaat aggcttattg aggatagaca tcaggttaag cttttgttaa
    28201 atgaagctca agaggaggag cagactgcaa attacctgct tgatttggca gctaaggtca
    28261 aaaacggtga gattattgat tttgtaaggt cagtatcgcc tgtcttgtat cgtctctttt
    28321 tgcggctgct tgagcaggct gtcccagatg ttcaaagcta tattattgat accaagaatg
    28381 atcaatatga cacttggaat tttaaggcga tggaaaaagc cgataatgac ctctttagga
    28441 gctatctggc acaaagacag ccacgtcatg tgacgacacg cagcttggct gatttacttg
    28501 ttttatcaga gcttccagct gatattaaaa gactagtggt agtcttaagg cagtttgaaa
    28561 aatcagtccg caatccccta gcacatttga tcaaaccctt tgatgaggag gagctatatc
    28621 ggacaactca tttttcctct caagcctttc tagatggttt gattcgctta gcagtttttt
    28681 ctggtgttaa ctatatcaaa gagcccttct attttgatgt cgttaatgct gtcattgaaa
    28741 aggagctgtt agacagcgcc aagccttagc tatttgaaag attagcaata ataaaaaacc
    28801 tgaacgatct gaacgaggct tctctaagct agctatgact agtcagctta gagccttaga
    28861 acaggtcttt caggtttttt atgtttagct agtgtggtta attaatgatt gaagctaatt
    28921 tcttctagca ggtagtcaat aaatcgctct cccatttttg agaggttagc cttttcgtgc
    28981 ttgataaaga caatctcaat cacatcaggg acatctaagg gaatagcgac aatctggtct
    29041 ccatttagat ttgtgtttaa aataccgctg gcaacggtgt agccatttaa gccaatcatg
    29101 agattaaata gagtagctcg gtcactcacc acaatagact tactgtgagg gatatgtgcc
    29161 atcatctcct ctgagaaata aaaggaattg tgaatcccct gatcatagct tagataagga
    29221 aaatcaagga gatcatcaat ggttaagctg gttttatttg ccagaggatt ggacttgctg
    29281 ataaagatat gcggtgtggt tttaaatagg gtggaaacgg tcaaatgatt ttcctcaaac
    29341 agcttggtaa ggacgtctcg gttgtagtca ttgataaaca aaacgccgat ttctgagcga
    29401 aaatttttca catcgtcaat gatttcccag gttcttgttt ctcgcaagaa aagctcgtac
    29461 tgggtcatat cagcccgctt taataaagag acaaaagcat tgacaacaaa ggcgtaatgc
    29521 tgagaggaaa cactaaagag ctcacgacta gtattgtgat ttttatagcg atcctctagc
    29581 agtgctgttt gttcaataat ttgtctggca taagatagaa actcaacccc gtccttggtt
    29641 aaggtaatgc ccttgggatt acgaatgaaa atagtaatgc ccatctcctg ctctaattcc
    29701 ttgacagcat tagacagact gggctgcgtg ataaataatt gcttagcggc ttcgttcatg
    29761 gaaccgcatt caacaatctt tataatgtat tgtagttgtt ggattctcat actgacagtc
    29821 tatcttaaat agtacaaaga atcaagtgcc tttattagag cttaagacaa ggtttcacaa
    29881 gcggtagcct agcttgtgcg gtgaagctag cttgatgcta gtgttgtacc caggtaaaaa
    29941 agagctggca aataggcagt tttatcgctt tttaccgctt atttttggca tgcctgtgtt
    30001 ttgataaacg gctggtcttg atcggtaaaa agtaatcgtg ataatatcag ataataccta
    30061 tttttccatt gctcttttaa ttttcttgtg ttatattaat aatattgata tatttaatgt
    30121 tttgagataa agggtggtga tggtgtaata tgactggaca aagtagtcat caggtattaa
    30181 ttcaaaagct gttggtcagc actcactatt tgacattatt tagagatgag ctgaagctag
    30241 ttgagaggac accatctatt ttgggaagtg agtttcctgt ctctcttgtt caaacggaat
    30301 taggtgatat tatcaccttg gtggatacct taaataagca gcagcgcttg attgagtcga
    30361 ccttttggta tgaggagtca gcctttaagc tcatgaacaa ggccttagat attgttgata
    30421 attggataaa ggggatagat ggcttaatta agctctgcca gtccaaggag gtctttcagg
    30481 ccattgttgg tgataaaaga acacgtgttt ttggtgtttt gattgatgtt ttttcttccc
    30541 taaaaattag caccatgtca ttgaaggaat ttgcagctcc ggctgctctt tgccattaga
    30601 ttaagctggg ctaagcttgg atagtggctg gttaagcctg caagttgccc ctctcatgac
    30661 aagtctaggc tttatttagg gtgagcagtg tgccaagggt gtattaagtg ctggttgctt
    30721 tgaagcttcg ccttgctagg ttagctgtga gtgatgtcac gataactgcg cgaaacagtt
    30781 atttctgaat tataatacag gttaaagtag gtacttttaa tgtttttcct attgtaaaat
    30841 ctatacaaaa taggatatat ttttgaaata gctgaacatt aacgtacagc aagctttatt
    30901 ttcttgctaa aaatcttttt tatacctttg tcgtgtgagt aatgtcaaaa ccctttgaca
    30961 agggctgtca aaaaagctat aatgattgag ataagttacc tttaagtgag tccagagagg
    31021 cgagcaaggt acacaggata agatgagagg gtttgctctc ttgattttcg tgtagcctcg
    31081 cttctttgga agtgaggctt ttatggtgtg actttcagtt ggtctcgtgg taatgattca
    31141 taagaccaat aaaccgctcg ttagacgggt gggcatgatt tgtttgggag taccccaagc
    31201 tgcatagaaa ggataggtta tgcgagaaga acgccctatt attgccttag attttccttc
    31261 ctttgaggag gtcaagtcat ttctgtcgct gtttccagct gatgagaggc tatacgttaa
    31321 gattggtatg gaactgtatt atgctgaagg accagatatt gtccgttatg tcaagtcctt
    31381 aggtcacagt gtttttctgg atttgaagct gcatgatatt ccaaatacag tcaaatcaac
    31441 gatggcagtc ctatcaaggc ttggtataga catgacgact gtgcaggctg ctggaggtgt
    31501 agagatgctt agagcagcgc gtgagggctt ggggcagggt ccgattctca ttgcggtgac
    31561 acagctaaca tcaactagcg aagagcaaat gcgtgaggat caaaacattc aatccacgct
    31621 gttagcatct gtgcttcact atgccaagcg taccgctcag gctaagctag atggcgtggt
    31681 ttgctcagcc catgaggtca aggccattaa gtcagaagta ccagcaggct ttgtgtgttt
    31741 gacacctggg attcgcccga caggtgctga catcggagat caaaagcggg tgatgacacc
    31801 tcatcaagct agagctatcg gaagtgacta tattgttctt ggtcgtccga tcactcaggc
    31861 tacagaccct gtcaaggctt atcaccagat taaggcagag tggaaccgtt agcagcagga
    31921 tcatcatgac acatatagct ggactatgac accaaggaaa agaggagaaa aatgacacta
    31981 gcagcacaaa ttgcaacaga tttacttgag attaaggccg tttacctaag accaaaggag
    32041 ccctttactt gggcgtcagg cattacatca ccgatttata cggacaatcg gatcaccctt
    32101 tcttatccaa aaaccagaag cttgattgaa aatggctttg tggagacgat taaggcagta
    32161 tttccagagg ttgaggtgat tgctggcaca gcaactgctg gtattccaca tggtgctatc
    32221 gttgcagata agatggacct gccttttgcc tatatccgca gcaagccaaa ggatcatgga
    32281 gcaggcaacc aaatagaagg gcatgtgcgc tgcgggcaaa aaatggtgat tatcgaggat
    32341 ttgatttcaa caggtggatc agttctggag gcggcagcgg cagctagtcg cgaaggtgct
    32401 gatgtactag gagtggtggc aatttttacc tatgaattgc cagtagcaag catcaatttt
    32461 gaaaaggcag ggctttcctt ggtgaccttg tctaattatt cagacctcat taaggtcgct
    32521 aaggccaagg gctatattga tgctgatggc ttggccctgt taaaaagatt taaggaggat
    32581 caaaagcatt ggcagcatga gagttaaaca gtgctgaaaa gctgctgaca tgctgactat
    32641 gtcttaagga gagaaaaaat gacttacaaa gatttacttg agataggtga gaccagttat
    32701 tatcagacgg atcgcttgac ttactacaaa aatcctgtgg tatctgagcg ctattttgat
    32761 aattacctta gctatcgtag catgccttct ttggctgatt tgaaaaagga cttggcctat
    32821 gtggcaaaag agcagcagga ttatcctagt cactacgcct ttctcttttt tgctgaaaat
    32881 gaagagctaa gtacagacat gcgagcttat ttgacagatc atcactttag ccttgaaaag
    32941 cacctgatct ttaccaatga gctggcaaag cttcacctaa aggagcgtga tatatcacca
    33001 gtcactattg aacagctctc agaaacaagc ttttctgcct atctggctta caaatatcag
    33061 gctaatttgg cttatggtga aacctatgcc aatcaatgca aggctgataa tgaagccaat
    33121 ctattgacaa acggctcaac catttattta gccatcaagg aagggaagat tatcggagat
    33181 attacggctt gggaatgtgg cgactatatt gaaatggacg atttcagtgt agatgaggcc
    33241 tatcgtggtc gtggtatcgg tacagcctta cagcgtaagg ccagtcaagg ctataagaag
    33301 gtcattctca tctcagaaga agctaatcgc gccatgtatg agcaccaagg ctatcaggag
    33361 gttgcttact actggacagc gctaaaaaca tcgactagat aagtgataaa gaaacagatt
    33421 ataggattga aggtgtaggc tcttatgagt atgactcttc aatccttttt ttctgagcgc
    33481 atttgctaat catacctaat gaataagtcg tagcctgtct agtggctcat tttaatggcg
    33541 tcttgctctg ttttatgatt aaatatagag aaaaagctat tgttagggca tgcttgttgg
    33601 tctagcaagg ctgatggatg ataggatagg gaattgatga tttttaaaga tgcaacagaa
    33661 atggcgcagg ctgttcgaga aggtagggtg agcccctcag ccttagtgag agacacaatt
    33721 aaaaaggctc aagcactcaa tcctgagttg aatgctatta cctcagagcg tttttcagaa
    33781 gctcttgctg aggcagcagc aagggatttt tctggaaagc catttgctgg tgtgcctatt
    33841 tttctaaagg atttagggca ggagcaggag ggccaattgg ccactgcagg atcagtgtta
    33901 tttaaggatt atcgtgcctc aaaaacggat tatgttgtgc agcgactaga ggagctgggc
    33961 tttattattt taggaagaag caatacacct gaatttggct ttaaaaatat tagtgatagt
    34021 cgcttacatg gtccggtaaa tctgccacag gacaagagcc gtaatgctgg tggttcatca
    34081 ggtggggcag cagctcttgt gtcctcagga atcaccttgc tggctcctgc tagtgacgga
    34141 ggaggatcca ttcggattcc tgcctccttt aatggcttga tcggtttaaa gccaagcaga
    34201 ggaagagtgc ctgtggggcc aggctcttat cgtggctggc agggggcgtc tgttcatttt
    34261 gctctaacga ggtctattcg agacacaagt cgtcttcttt atcacttgca ggtttatcag
    34321 gtagaaagcc cttttccatt agtgccatta accaaagaag agctttttca ccctttagac
    34381 agacccttaa ggattgctct ttatgatcac atgatagatg gaactaccgc ctctatagat
    34441 gctcagacag ctttaaccga ggcctgtcat tttctaaaag agatggggca tgaggttgtg
    34501 cgattagata agcttcctct agatatacca aaggttatga gggattacta cctgatgact
    34561 agtgttgaga cagctgctat gtttgctgat agccaagaag cccttggtcg tcaggtgacc
    34621 aaagcagata tggaggtcat gacctgggct atctaccaag cgggtaagga tattcttgct
    34681 tcggtctatt ctcaggcgct gcagcgctgg gaccattata gtgctgaaat ggcaagcttt
    34741 catgagcagt atgatctttt gctgaccttt accgccaata cgcctgctcc aaagcatgga
    34801 cagttccagc caagcaagga gctaatagat aagctggcta aggcggaatg ctacccctcc
    34861 agtcagcgcc tagcgctagt agaagccatg tttgagcaga gcttgttcat aaccccttac
    34921 acagctttgg caaatctgac aggccaacca gctcttagtt taccaaccta tgaaacgtct
    34981 gctggattgc cgatgggcat tcaattgata gctgctaaag ggcgagaaga cttattgctg
    35041 ggaatagcta gacagtttga acgggctgga ttgttaaagc tacctggtta aatattataa
    35101 aacagagcta atctattata ggttagcttt tttgttaaat cgagcatatc tagtctctta
    35161 taagattagt caatgctata ctgtcattaa taatgaaaaa ggagttcttg atgaaaaaag
    35221 gagttgcttt actttctgtt agcttggcga gcttgctgtt agccgcctgt gggtcacagc
    35281 catcagctca aaaaacaagc tgggaaaaga ttaaagataa aggtgtttta aaggttgcta
    35341 cgcctgcgac ctaccagcca acatcgtact ataatgatgc caatgaattg gtcggctatg
    35401 aggttgacct gatgaaggaa attgggaaac gccttgatct taaggtgaag ttcattgaaa
    35461 caggctatga tcaggctttt acttcggttg atagcggtcg tgttgatgtt tctctcaata
    35521 attttgacat tacagccaag cggcaaaaaa aatacaacat ctcaacgcct tataagtatg
    35581 gtgttggggg aatgattgtt cgtgctgatg gcagctcagg cataagcaag gctgacctaa
    35641 gcgattggaa agggaaaaaa gcagctggcg cctctggtac agaatacatg aaggttgcca
    35701 agaagcaagg tgctgaatta gtcacttatg ataatgtgac gggtgatgtt tacctgaacg
    35761 atgttgctaa tggcagaaca gactttattc ccaatgatta tcctgcacaa aagctttttg
    35821 tggattacat gaagtctcaa aatcctaacc tcaatgtcaa aatgagtgat gtgctgtata
    35881 atccgacagc acagggcatt atcatgagta aaaaagatga cacccttaag aaaaagattg
    35941 atgcggtcat caaagacatg aaacaagatg gcagcttgaa aaccatttca aagacatact
    36001 atgctggtca ggatttgaca gttccttttg gtaaggacaa gaaaattcca gtcattgatg
    36061 ccagtgatgt ggactagtgc cttagacaaa ggagctctaa agcgatgctt aatcttagat
    36121 tgatactaga gagcttgggc tttgttttgt caggtttgcc ctatacctta ggcatttctt
    36181 ttttaagctt tctaacaggc cttttgctgg gcttgctttt agccttttta aggcgttcta
    36241 ctagtcactt tagtcattat ctggtcagga gctatgtgtc cataatgcgt ggcgttccta
    36301 tgattgtggt gctctttgtc ctttattttg ggcttcccta ttatggctta gaactgtctg
    36361 ccttgttatg tgcctatttg ggcttttcac tggttagtgc agcctatatc tctgaggtct
    36421 ttcgtgcctc gattgatgct attgatcagg gacaatggga ggcagcaagg gctttggggc
    36481 tgccttatgt cagcattgtc aagcatgtga ttctgcctca ggcctttcgt attgctattc
    36541 cgcctttagg aaatgttgtg attgatatgg tcaaaagttc gtctttggca gctatgatta
    36601 ccgttcctga tatttttcaa aaggctaaaa ttattggtgg cagggagtgg gattacatgt
    36661 ctatgtatat cttggttgcc tttatttatt gggtgattgc ctttttgctg gagcgctgtc
    36721 agggcttttt agaaaagagg ctgcgcttac tctcttaaaa accgaatatt taccctagaa
    36781 atattgtatt tctagggttt ttatgataaa aatatgatag actaaagtag cctaatcagt
    36841 tagttagctt tgtcaagaac tgactggcta gagtgttgga ggtaggatat ggcagactct
    36901 attgtatttc ggaaaaatca tatgatttca actcaggcct ttgctcgagt gctggaagcc
    36961 tcagggatta aaagaccgac taaggacgag gctagattat cgcaaatgct aaagcattcc
    37021 aattatctat ggacagcatg ggaaggtgac aagttagttg gtgttgctag agcccttact
    37081 gactatgctt atgtctgcta tatttctgac ctagcagttg atcaggcata tcagggtcaa
    37141 gggataggca agcaattgct gtcttttatc tcagaggatc ttggagatgc tgttgctctt
    37201 gtattgctgt cagcaccttc ggcgatgtcc tattacccta agcttggctt tgaacaatca
    37261 gacaaagcct tcattattcc acgaaaaccg ttttagagag gtatctaatg acacattcag
    37321 cttggcatga tgagattaag caagtgttac ctaaggatta ttatcggcgt atcaatcgct
    37381 ttttagatga ggtctatgcg actggagtgg tttacccgcc cagagacaat gtgtttaagg
    37441 ccttacaggt aacgccatta gaagagacaa gagtgcttat tttagggcag gacccttatc
    37501 atggccctct tcaagctcag ggactttcct tttcagtgcc tgactccatt cctgctccgc
    37561 catctttgca aaatattttg gaggaattag cagcagatat tggagtaagg aatcatcacg
    37621 atcttagcag ctgggctgag cagggagtgt tgctcttgaa tgcctgcttg accgttccag
    37681 aaggacgcgc caatgggcat gcaggtctca tctgggagcc ctttaccgat gcggttataa
    37741 aggtcttgaa tgctaaggat aggcctgttg tgtttatcct ctggggagcc tatgcgagaa
    37801 gaaagaaggc cttgattact aatccgattc accatgttat cgaaagccct caccctagcc
    37861 ctctgtcagc ctatcgtggc ttttttggca gcaagccctt ttcaagagct aacgccattt
    37921 tagaaaaaga aggcctagga cagattgact ggctgcgcta ggcattgagg caggctatta
    37981 tggctaagca ggacgattta ccaataaagt atccggcttt ggagacttgg gtatacctag
    38041 ctaaatagag attgatgata tcagggatca agacagttac gtccgatatg tcaagcaaaa
    38101 caaataatca ctgcctagat aaatcagaaa ttgctagggt tatgcttgat tatcctgata
    38161 agcagataag tagatttgac ataggagggg tcatgttatt aattaaaaat gggcgtgtga
    38221 tggatccaaa atcacagcta gatcaggtgg cagatgtctt aattgataat ggaaggattt
    38281 tacggattgc tccagacatt gagcatgatg aggtagagca gatcgatgcc agtggacttg
    38341 ttgttgctcc tggtttagtg gatattcatg ttcattttag agagccgggt caaacgcaca
    38401 aggaggacat tcatacaggt gctctggcag cagctgctgg tggggtgaca acagtagtca
    38461 tgatggcaaa caccaatcct gttatatcag atacggaaac cttacaggct gttctagcaa
    38521 gtgctgctaa agaaaaaatt aacatttata ccaatgctag tgtgaccaag cggttcaatg
    38581 gccaagagct aacagacttt aaagcgctct tagcagctgg tgcggtcagt ttttctgatg
    38641 atggcattcc tttagagagc tccaaggtct taaaggaagc attggatttg gctaaggcca
    38701 acaagacctt cattgccctg catgaggagg atccccaatt aaacggtgtc cttggcttca
    38761 atgagcatat cgctaaggat cattttcatt tttgtggcgc tactggtgtg gcagaatata
    38821 gtatgattgc cagagatgtg atgattgcct atgatcgaca agctcatgtt catattcaac
    38881 atttatctaa ggctgagtct gttaaggtag ttgcctttgc tcagcagtta ggtgccaagg
    38941 tcacagccga ggcaacaccg cagcattttt ctaaaacaga agacctttta cggcttgcag
    39001 gggcaaatgc caagatgaat ccgcctctaa gaacagaaca agatagatta gcagttattg
    39061 aggggctcaa atcaggtgtc atagctatta ttgcaacgga tcatgcacca catcatcgtg
    39121 atgaaaaggc cgttgctgat ctgaccaagg caccatctgg aatgaccggc ttagaaacct
    39181 cattgtcatt aggcctgaca aatcttgtgg agccgagcca tctttcattg atggcgttat
    39241 tagagaaaat gaccattaat ccagcctcac tatatagctt tgatgctggt tatttggctg
    39301 agtctggccc tgctgatctt gttatttttg ctgacaagga ggagcgtttg gtaacagaag
    39361 cctttgcttc aaaggctagt aattcacctt ttattggcga aaccctaaag ggagttgtga
    39421 aatacaccat tgctaaggga caaattgttt atcaggcaga caactaatca acacttaaaa
    39481 agctgagcat ctgatagtaa ctgatgctca gctttttgat ttagtgatgg cttgcgggct
    39541 gctgcttgct taagttcaag ccccaaggaa tgagattttc agattgctgc ttgattcgct
    39601 tcatattatc ctgatgcctt aggataatga ttgctgctag cacaacgatg gtaatggtta
    39661 atagccaatc gtagctaggc aataaaaagt gggcggcagg aaaagtcaga acgctaatca
    39721 cagctactac agacgctgtt agactagcta gtgaaatcat gctaaataaa taaagcgtta
    39781 gcacaaacac agccgctaaa aaaaggagat agagtggggc aaagcctagc aagacaccag
    39841 cactggttgc gactgccttt cctcccttga agccagcgaa aataggaaag gtatgcccta
    39901 ggacagcaaa aaagccaata gtaattggtg agatattgct agcgccaacc aaaaccggaa
    39961 gaagcgtggc aagcgtgccc ttaaaaatat caatcaataa ggttgcagca ccagctttta
    40021 gcccaagaat ccgaaacgta ttggtcgtac cggtattacc tgagccatgc tcacgcaggt
    40081 tgatgttata gaaatactgt ccaatccata agcctgttgg aatggagcca agtaaatatg
    40141 ctgtaagaat taataggatc aatttcataa catacattat atcataatga ttgatttaag
    40201 cggaagcagt tacaaagaat tacgaaaaaa tcttaaatta ttttgcaaaa ttctcaaaaa
    40261 acctgtaaga taaaaaagat gaaaacgtct ggaggtcaac ttggctaaga aagaaataag
    40321 cataacaaat tataatgatg atgccattca ggtcctagag ggcttagagg cagttcgtaa
    40381 aagaccaggg atgtatatcg gatcaaccga tgcaaccgga cttcaccatt tgatttggga
    40441 gattgtcgac aatgctgttg acgaggcctt atctggcttt ggaaatgaga tcgatgtgac
    40501 gctaaacaag gatggttctg ccaccatttc tgacagcgga cgaggcatgc cgaccggaca
    40561 gcacgccctt ggtataccaa ctgttcaggt catctttacc atcttgcatg caggtggtaa
    40621 atttggtcaa ggaggctata aaacctcagg aggcctgcat ggtgtgggct cttcagttgt
    40681 aaatgcccta tcgtcatggc tagaggtgga aatcacgaga gacggagcgg tttacaagca
    40741 gcgctttgaa aatggcggta ggccagtgac aggcttagaa aaaatagcta cagctccaaa
    40801 aagcaaatca gggacaaggg ttactttcat gcctgatgac aagatttttt cgacaactga
    40861 gttcaagtgg aatactatcg cagagcgtct aaaggaatct gcttttctgc taaagacggt
    40921 taaaatgacc ctgactgatc tacgaggtga cgatccggtc gttgaggaat ttcattatga
    40981 aaatggtgtt caggattttg ttgcctatct caatgaggac aaggaaacct tgactcctgt
    41041 gatttacatg gaagggcagg agcaggattt tcaggttgag gtcgctttgc aatacaatga
    41101 tgggttttca gataacattt tgtcctttgt taacaatgtt aggacaaagg acggtggcag
    41161 ccatgaaact ggcttaaaat cagctattac aaaggccatg aatgactatg cccgcaaaac
    41221 cagcctacta aaggaaaagg ataaaaactt ggagggctca gattatcgtg agggcttgtc
    41281 tgcagtgtta tcgatccttg taccagagca gcatttgcaa tttgaagggc aaacaaagga
    41341 caagctagga agcccactgg caaggccgat cgttgagagc attgtatcag aaaagctgac
    41401 cttcttttta cttgaaaatg gtgagctggc aggtcatttg attcgtaagg ctatcaaggc
    41461 aagagacgcg cgtgaggcag ccagaagagc gcgtgatgag tctcgaaatg gtaagaaaaa
    41521 caaaaaggac aaggggcttc tttctgggaa attaactcca gcccagtcca aaaatcctaa
    41581 gaaaaacgag ctgtacctag tcgaggggga ctcagctgga ggctcagcta agcagggcag
    41641 ggatcgtaaa tttcaggcaa ttctcccctt acgtggtaag gttttgaaca cagaaaaggc
    41701 caagatggct gatattctca aaaatgagga aatcaataca atggtttata ccattggcgc
    41761 aggtgttggt gctgatttca atcttgatga tattaattac gacaagatta ttatcatgac
    41821 cgatgctgat acggatgggg ctcatattca gaccctgctg ctgacctttt tctaccgtta
    41881 tatgcggccg ctggttgaag caggacatgt ctatattgcc ttgcctcctc tttataaaat
    41941 gtcaaagggt aaaggcaaat cggagaaggt ttcctatgct tggacagatg gtgagctgga
    42001 ggatcttcgc aaggaatttg gtaaaggtgc aagtctccaa cgctataagg gacttgggga
    42061 gatgaatgcc gatcagctat gggaaaccac gatggaccct gacacacgaa cccttatccg
    42121 agtgacgatt gatgacctgg ctagggcaga gcgacgcgtt tcagtcctca tgggagacaa
    42181 ggctgcccca cgccgtcaat ggattgagga caatgtcacc tttaccttgg aggaaaatac
    42241 ggttttttaa ggcatttttc ctaaggaggg ttctaaaata tctcatatca aattgctatt
    42301 catgtgctca gcattcattt atcaaggatt gtaatcattg aggtaacagt gatgaagcta
    42361 gatatttgtc aacaaagcta cagtcttcag tggggaggca cctattattt tgcattgaca
    42421 gattatccca atatcaaggc ttgggaactg gaaaagctag cagccttttg tgcctacgaa
    42481 aaatggaatc atcgtcaaac agacattagc tgtcaggaca gcaagcttct tgaagaggtt
    42541 catcaatttc ttgaagcaca tgcttgtgcc tatctcttta ggcctagctg taaattggtg
    42601 gcttcaacat ttaacatcaa tggagaggca gtctgttgtc cttatttaag tcatacctgc
    42661 actgtagcgg ctgctctaag catttttaag acaggaaggc tattgtctgc tgtaagagct
    42721 tttggggtaa cggcacagga gttggctagg agtgatcgaa atgctgctgg tgatcctgct
    42781 gattattttc attatgtgat gcttggctgg tccaatacga cctcaggcta tcgcttggct
    42841 atggagagat tgcttaatcg tatgccaaat gaaaaggact taagagagca ttttgtaccc
    42901 ggagttagct ttcactatag ctattctgat atttgtcaga tgaaaggcta tgtttttgat
    42961 ggctatcacc ctgccaagat caaagacgag cttagtttgg aggaattgca ggcttgcatt
    43021 attcctaaaa gctggcagca gcgctttgaa gcaattattc caaaggcctt acgctcaagg
    43081 gttcattacc tagactataa aggcgaaggc ttggtcgagt ggtctgatag ggtttatcag
    43141 ctgttaagag tgatcagtga cagctagctg taaataggct agctttatac tattttttga
    43201 atataataga caatctaaca gaaaggaaag ctcagtgaga ggtctcttgc tgggtgtggg
    43261 atggatttcc tagaaactgc taatcctagc gataggggag cgtagcgagc ccattctgaa
    43321 agctcctgcc gtagtgaaaa gaagataatc gcttacgatt atcttcgagg gaaatttcga
    43381 gccgaagtct cgaaatttag gaatggaacc gtaggttcgc ttctgtcccc actacctaaa
    43441 ggaactttca aaaaaaacta attaaagaaa gagatatctt tctgaaagaa acaaagaaag
    43501 gaatgttcag ctagtttact aactgaacac gggactattt ttcctagaaa aatcggtaac
    43561 ctcctagtgt ccaaggacac gtcgtcagtt ccagcatttt ttacggaaaa atttcgcaag
    43621 cgaaacgtcc ctttgtatct tatgagtaat attcaaaaca tgtcccttga ggacatcatg
    43681 ggagagcgtt ttggacgcta ctccaaatac atcattcagg agcgagcgct tcctgatatt
    43741 cgagatggtc taaagcctgt tcagcgccgc attctttatt ctatgaataa ggacggtaat
    43801 acctttgaaa agggctaccg caagtcagcc aagtctgttg gtaatatcat gggcaatttc
    43861 cacccgcatg gagattcttc gatctatgac gctatggtac gcatgagtca ggattggaag
    43921 aatcgtgaaa ttcttgtgga aatgcatggc aataacggct cgatggacgg tgatccaccg
    43981 gcagctatgc ggtacactga ggcaagatta tctgaaattg ctggttacct gctacaggac
    44041 atcgataaaa aaacagtgcc atttgcttgg aattttgacg ataccgaaaa agagccaaca
    44101 gtattgccag ctgcctttcc aaatctattg gtcaatggct catcagggat ctcagcaggc
    44161 tatgctacag atattccacc acataatttg tcagaggtga tcgatgctgt tatttatatg
    44221 attgaccacc caaatgccaa gctggataag ttaatggagc tattgccggg tcctgatttt
    44281 ccaacaggtg gtattatcca aggagcagcc gaaattaaaa aagcctacga aacaggtaag
    44341 agccgcgttg ttgttcgctc cagaactgaa attgaggatc taaagggagg caagcagcag
    44401 atcattgtga ccgaacttcc ttatgaggtc aataaagctg tcctagttaa aaaaattgat
    44461 gatgttcggg ttaataacaa ggttccagac atagcagagg tgcgtgatga gtcagaccgt
    44521 acagggctac gcattgctat tgagctcaaa aaagacgctg acagccaaac catcttgaat
    44581 tatttgttga agtataccga gcttcaagtc aattataatt ttaatatggt tgcgattgat
    44641 cattttacgc ctcgtcaggt tggattgcaa aaaatcttat caagctatat cgctcaccgc
    44701 aaaagtatta ttatcaagcg ctctcagttt gacaaggaaa aggctgaaaa gagattgcat
    44761 attgttgagg gcttgatacg tgtcttatct attttagatg agattatcgc gctgatccga
    44821 gcttctgaca ataaggctga cgccaaggaa aacctaaagg tcagctatga tttttcagag
    44881 gaacaagcag aggctatcgt aaccttacag ctttatcgac tgaccaatac agatattgtt
    44941 accctccagc aggaagaaca tgacctaaga gagctcatca caactctctc tgccattatt
    45001 ggtgatgaag caaccatgta taacgtgatg aagcgtgagc taagagaggt caagaaaaag
    45061 tttgcagggc cgcgtttatc agagctgcag gctgaaagcc aagcgattga aattgattct
    45121 gctagtctta ttttggagga agaaaccttt gtcagtgtga ctcagggagg ctatatcaag
    45181 cgaacaagcc ctaggtcatt tcacgcctca agccttgagg aaattggtaa gcgtgatgat
    45241 gatcatctga tctttgttaa gcaggctaag acaacagacc acctgttact ctttactaat
    45301 ttaggtaatg ttatttaccg tccggtctat gagctgactg acttgcgctg gaaggacatc
    45361 ggggagcatt tatcacaggc tattgctaat tttgctgctg atgagctggt gatatatgct
    45421 gagttgatcc agtcctttga agagggacta tatatctcag tgacacagca tggactgatt
    45481 aaacggtttg agcgcaagga gctgacgcct tggcgaacct acaaatcaaa atcaattaaa
    45541 tacgccaagc taaaagacat agatgatcgc attgtggcaa tagcaccaat tatcatggaa
    45601 gatcttcttt tggtgacgca gcagggctac gccttgcggt tttctagcca agaaataccg
    45661 attcagggcc taaaggctgc cggagttaaa ggaattaacc taaaggctca ggattacttg
    45721 gtttctgcct gcccagtcaa tgctgattcc ttctttgtgc tgacgcaaag aggagcacta
    45781 aagcgagtgg cgattgctga tattccacag accagccgag ctaacagagg tctgccggtg
    45841 ttacgagaat taaagaccaa gccacacaga gttttcttgg caggaatggt aaaaggagat
    45901 actacaacag gtaccattga cttatttaca catgattcag aggacacagc tagtgaccag
    45961 caattagagg ttattagtaa gactggtcaa caataccagc ttgctctcaa tagcctgtct
    46021 ctatcagata ggacaagtaa tggctccttt atttcagaga gcatttcaga tcaggaggtc
    46081 gctgctgcaa ggctcatcta gccaaagctt tttcgctgta ccagtgaggg ctctgagtct
    46141 ttcatcgaaa aaagatgcaa aacaatgaag aaaagaatac aaaaagaaaa gaggtaggat
    46201 aatgacaaca gctattgatt gggaaaactt aggctttgaa taccgtaagc tgccatttcg
    46261 ctatgtatca tattacaagg acggcaaatg ggacgcaggt cgcttaacag aagatgctac
    46321 cctgcacatc tcagaaagtg caccagctct gcattatggg caacaagcct ttgaaggctt
    46381 aaaggcctat cgcactaaga acggctctat tcagctattt cgcccagacc gcaatgcagc
    46441 tcgcttacag gcaacagctg accgtttgct gatgccacag gtatctaccg agcaattcat
    46501 tgacgccgtt aagcaagtgg taaaggcaaa tgaggatttt gtaccgccat atggaactgg
    46561 tgctaccctt taccttagac ccttgttaat tggtgttggc gatattatcg gtgttaagcc
    46621 tgctaacgaa tatatattta tagtttttgc catgcctgtt ggcaattact ttaaaggcgg
    46681 gcttgcgccg accaacttta tcgtctctga ggattatgat agagcagctc cttatggcac
    46741 tggagctgcc aaggttggtg ggaactatgc aggtagctta ttgccaggaa aagcagctaa
    46801 gacagcaggg tattcagatg tgatttacct agatccagca actcacacta agattgaaga
    46861 ggtcggagcc gctaatttct ttggcatcac tgccaataat gaatttatta cgccgcttag
    46921 cccatcaatc ttgccttcaa ttaccaaata ctccttactc caattagccg aagaaaggct
    46981 tggtatgacc gctattgagg gtgatgtgcc gattaatgat ttggaccgat ttgttgaggc
    47041 aggagcttgt gggacagctg ctgtgatctc accaattgga ggcattcagt atcaggataa
    47101 gctacatgtc ttttacagcg agactgaggt tggtccagtg acacgtcgat tatacgatga
    47161 gctggtcggt atccaattcg gtgatatcga agcaccagaa ggctggattg tagctattga
    47221 ttaaaataag tgaagcttgc tattgcaagc tcttttgatt ttgtgtaaaa tagacaaggc
    47281 gaggtgaagt gatgagtaaa aaagagaaaa aaattgaact gcaattatgc gatcaacaag
    47341 taacagtcaa caataccaag atagacggtt atcagttaca aattggcaag cgtgtcgttg
    47401 gcgagattgc agagcttgat ggcaagtttg ctgtcttaaa agacagcaca gtagatgctt
    47461 tttttaaaac attagagcaa gcagttgaaa atattattga aaactataat ttgaaccact
    47521 aaaaatgctt aaaaagactt gtcagcttac aaaaactatg gtagaatagt ttttgttgtt
    47581 acggaaagat agcgaagagg ctaaacgcgg cggactgtaa atccgctcct ttgggttcgg
    47641 gggttcgaat ccctctcttt ccatgcctaa gctattaggt tcattgtttt aatgatgata
    47701 ttggggtata gccaagcggt aaggcaaggg actttgactc cctcatgcgt tggttcgaat
    47761 ccagctaccc cagtcagagg tatcagatta gcgtctgaga tcgtcaagga taaaagttgt
    47821 tgtcattgcg ggttaccttg agaaaatata ttgttatcaa aagctagcat aagctagctt
    47881 ttgttggagg attttttaga atgaatgaat ttgaagattt gctaaacagt gttagcgaag
    47941 tcaatcctgg tgatgttgtc actgcggagg ttttgacagt tgataacggt caagcaaacg
    48001 ttgttattga aggcacaggt gttgaaggcg ttttgacact tcgtgaattg actaacgatc
    48061 gtgaagctga tattaatgac tatgttaaag ctggcgacac cgttgaagtg cttgttcttc
    48121 gtcaagttgt aggtaaagat actgatacag ttactttcct agtatctaaa aaacgtttgg
    48181 aagctcgtaa ggcatgggac aagcttattg gtcgtgaagg tgaagtcgtt actgttaagg
    48241 ggactcgtgc tgttaaaggt ggactttcag ttgaatttga agggcttcgc ggatttatcc
    48301 ctgcttcaat gattgacact cgttttgttc gcaatacaga aaagtttgtc ggtcaagaat
    48361 ttgacgctaa aatcaaagaa gttgatgcag cagaaaaccg ctttatctta tcacgtcgtg
    48421 aggttgttga agaagcagct aagcaagcac gtgacaaagt cttttcaaca ctttcagaag
    48481 gttcagtggt aactggtact gttgcgcgtt tgacaagctt tggtgctttt attgatcttg
    48541 gtggtgttga cggtcttgtt cacgtaactg agctctcaca tgagcgtaat gtgtcgccta
    48601 aatcagttgt ttctgttggt gaagaggttg aggtgaaggt acttgctctt gatgaggaag
    48661 caggtcgcgt atcactatca cttaaagcaa caacacctgg accttgggat ggcgttgagc
    48721 aaaagcttgc acaaggtgat gttatcgaag gtaaggttaa gcgcttgact gactttggtg
    48781 cttttgttga ggtattacct ggaattgatg gacttgtaca catttcacaa atctcacaca
    48841 agcgtgttga aaatccaaag gacgtgctta ctgtaggtca agaggtaact gttaaggttc
    48901 ttgacgttaa cgctgctgat gagcgtgtat cattgtcaat caaggcactt gaagagcgtc
    48961 cagcacaagc agagggtgaa aaggaagaaa aacgtcaatc acgtccacgt catcaaaaac
    49021 gtgaagctaa gcgtgattat gagcttccag aaacacaaac tggattttca atggctgacc
    49081 tttttggtga tattgaatta taatactata aaaa
//
LOCUS       DARYMD010000010        48181 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYMD010000010 DARYMD010000000
VERSION     DARYMD010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48181
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            121..255
                     /gene="rpmH"
                     /locus_tag="TU818_000505"
     CDS             121..255
                     /gene="rpmH"
                     /locus_tag="TU818_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL0923356.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            542..1267
                     /locus_tag="TU818_000506"
                     /pseudo
     CDS             542..1267
                     /locus_tag="TU818_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678571.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            1286..2599
                     /locus_tag="TU818_000507"
     CDS             1286..2599
                     /locus_tag="TU818_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0923357.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGCNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            2700..3587
                     /locus_tag="TU818_000508"
     CDS             2700..3587
                     /locus_tag="TU818_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0923358.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LISLISFAQFKFLGNDVEY"
     gene            3600..4430
                     /locus_tag="TU818_000509"
     CDS             3600..4430
                     /locus_tag="TU818_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL0923359.1"
                     /translation="MRKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDHLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            4446..4901
                     /locus_tag="TU818_000510"
     CDS             4446..4901
                     /locus_tag="TU818_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL0923360.1"
                     /translation="MLYDVLENIRRYKGIHRHLDVAIDFLLTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDDGDAVTKCLIKVLMED"
     gene            4926..5576
                     /locus_tag="TU818_000511"
     CDS             4926..5576
                     /locus_tag="TU818_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL0923361.1"
                     /translation="MSSKKRKLMQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLY"
     gene            5605..6525
                     /locus_tag="TU818_000512"
     CDS             5605..6525
                     /locus_tag="TU818_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL0923362.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINERLDIGSVR
                     SPLPELTENDLVICQQAAALIKQTKEQFCS"
     gene            6540..7424
                     /locus_tag="TU818_000513"
                     /pseudo
     CDS             6540..7424
                     /locus_tag="TU818_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            7424..7696
                     /locus_tag="TU818_000514"
                     /pseudo
     CDS             7424..7696
                     /locus_tag="TU818_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
     gene            complement(7738..8562)
                     /locus_tag="TU818_000515"
     CDS             complement(7738..8562)
                     /locus_tag="TU818_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL0923363.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFIFECQKSREAMDQKAPNLQNYNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
     gene            8791..9564
                     /locus_tag="TU818_000516"
     CDS             8791..9564
                     /locus_tag="TU818_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL0923364.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDSLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            9536..10132
                     /gene="rnmV"
                     /locus_tag="TU818_000517"
     CDS             9536..10132
                     /gene="rnmV"
                     /locus_tag="TU818_000517"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL0923365.1"
                     /translation="MQRGCLELTEKLKIQEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYHGERIRKLIMRAVPTARHAFLRRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMTSYQTEQ"
     gene            10476..11348
                     /gene="rsmA"
                     /locus_tag="TU818_000518"
     CDS             10476..11348
                     /gene="rsmA"
                     /locus_tag="TU818_000518"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL0923366.1"
                     /translation="MRIADYSVTKSILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGF"
     gene            11509..12381
                     /gene="rsgA"
                     /locus_tag="TU818_000519"
     CDS             11509..12381
                     /gene="rsgA"
                     /locus_tag="TU818_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL0923367.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNTNLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALGNGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            12390..13052
                     /locus_tag="TU818_000520"
     CDS             12390..13052
                     /locus_tag="TU818_000520"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL0923368.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            13045..13677
                     /locus_tag="TU818_000521"
     CDS             13045..13677
                     /locus_tag="TU818_000521"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL0923369.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            13679..14950
                     /locus_tag="TU818_000522"
     CDS             13679..14950
                     /locus_tag="TU818_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL0923370.1"
                     /translation="MDLILFVLVLVLIGLAAYSFVSIKHLQSRLEKALDDNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMVIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIH
                     SKYLNPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEGYQDQSTQSLLHIPLLEEADDED"
     gene            14940..15878
                     /locus_tag="TU818_000523"
     CDS             14940..15878
                     /locus_tag="TU818_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL0923371.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNIRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRIGEGEMTNRIFAMDNRSFYKPKY"
     gene            15978..16793
                     /gene="purR"
                     /locus_tag="TU818_000524"
     CDS             15978..16793
                     /gene="purR"
                     /locus_tag="TU818_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL0923372.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSYRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            16830..19334
                     /locus_tag="TU818_000525"
     CDS             16830..19334
                     /locus_tag="TU818_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL0923373.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSHQVKADDAKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKATEETLSERKKELAETNTNIAETEGEIANLEATK
                     KEQIAELAKAEELLETYSSMSEEDLAKSIEKHETELETINTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLTAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKETVHSQLTSDLAANKAALAAKEAELQRLQNGVATAQLNVAGSNKLIL
                     PKDYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQVDASGHRGVGPHDQTIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVESLNEHFVIFP
                     ESDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            19517..19930
                     /gene="rpsL"
                     /locus_tag="TU818_000526"
     CDS             19517..19930
                     /gene="rpsL"
                     /locus_tag="TU818_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL0923374.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            19951..20421
                     /gene="rpsG"
                     /locus_tag="TU818_000527"
     CDS             19951..20421
                     /gene="rpsG"
                     /locus_tag="TU818_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL0923375.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            20964..23042
                     /gene="fusA"
                     /locus_tag="TU818_000528"
     CDS             20964..23042
                     /gene="fusA"
                     /locus_tag="TU818_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL0923376.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            23423..24433
                     /gene="gap"
                     /locus_tag="TU818_000529"
     CDS             23423..24433
                     /gene="gap"
                     /locus_tag="TU818_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL0923377.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAHL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDKFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKDVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            24977..25831
                     /locus_tag="TU818_000530"
     CDS             24977..25831
                     /locus_tag="TU818_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL0923378.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            26041..27237
                     /locus_tag="TU818_000531"
     CDS             26041..27237
                     /locus_tag="TU818_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL0923379.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLVLPVDSKEANAF
                     ADYTEVKVTEGEAVDTGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            27660..28181
                     /locus_tag="TU818_000532"
     CDS             27660..28181
                     /locus_tag="TU818_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL0923380.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            28257..28628
                     /locus_tag="TU818_000533"
     CDS             28257..28628
                     /locus_tag="TU818_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL0923381.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLDEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            28665..30011
                     /gene="glnA"
                     /locus_tag="TU818_000534"
     CDS             28665..30011
                     /gene="glnA"
                     /locus_tag="TU818_000534"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEL0923382.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGTVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKGGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
     gene            30244..31902
                     /locus_tag="TU818_000535"
     CDS             30244..31902
                     /locus_tag="TU818_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0923383.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKD"
     gene            32071..32985
                     /locus_tag="TU818_000536"
     CDS             32071..32985
                     /locus_tag="TU818_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923384.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLAVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILATDMIISIADPRVRLG"
     gene            32995..34026
                     /locus_tag="TU818_000537"
     CDS             32995..34026
                     /locus_tag="TU818_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923385.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASIGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            34038..35084
                     /locus_tag="TU818_000538"
     CDS             34038..35084
                     /locus_tag="TU818_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923386.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMVDRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            35084..36019
                     /locus_tag="TU818_000539"
     CDS             35084..36019
                     /locus_tag="TU818_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0923387.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQNHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERKRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEAEQYRAECGL"
     gene            complement(36648..38330)
                     /locus_tag="TU818_000540"
     CDS             complement(36648..38330)
                     /locus_tag="TU818_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL0923388.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(38332..38562)
                     /locus_tag="TU818_000541"
     CDS             complement(38332..38562)
                     /locus_tag="TU818_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL0923389.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            38848..39546
                     /gene="tsaB"
                     /locus_tag="TU818_000542"
     CDS             38848..39546
                     /gene="tsaB"
                     /locus_tag="TU818_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL0923390.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLAELVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            39549..39974
                     /gene="rimI"
                     /locus_tag="TU818_000543"
     CDS             39549..39974
                     /gene="rimI"
                     /locus_tag="TU818_000543"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL0923391.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNH
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            39964..40980
                     /gene="tsaD"
                     /locus_tag="TU818_000544"
     CDS             39964..40980
                     /gene="tsaD"
                     /locus_tag="TU818_000544"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL0923392.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAEEITDIAVVIPPLRLCGDNAGMIALAAVVEYEKGHVAGLDLNAKPSLAFDS
                     FHQQ"
     gene            41002..42030
                     /locus_tag="TU818_000545"
     CDS             41002..42030
                     /locus_tag="TU818_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL0923393.1"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSVYTISSMLNT
                     FYFRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQIYQKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILLSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRCYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TU818_000546"
     CDS             complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TU818_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL0923394.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(42888..44060)
                     /locus_tag="TU818_000547"
     CDS             complement(42888..44060)
                     /locus_tag="TU818_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL0923395.1"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAG
                     TGGGRCNVTNSGSHDELIAGIPGNGRFLYSVFSQFDNHDIIAFFKENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLISTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKTLMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKQLPIPITGKISLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDVNAHTGGFNITAALCSGWVAGSSQS"
     gene            44186..44716
                     /locus_tag="TU818_000548"
     CDS             44186..44716
                     /locus_tag="TU818_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL0923396.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            44761..45348
                     /locus_tag="TU818_000549"
     CDS             44761..45348
                     /locus_tag="TU818_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL0923397.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAIADNPFAALGGLFD"
     gene            45452..46174
                     /locus_tag="TU818_000550"
     CDS             45452..46174
                     /locus_tag="TU818_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL0923398.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRRIYT
                     ESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKKHQL
                     DTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVMLVLL
                     TSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGHTPR
                     TRRLTCPHCHQKSYCLELAKEK"
     gene            complement(46216..46515)
                     /locus_tag="TU818_000551"
     CDS             complement(46216..46515)
                     /locus_tag="TU818_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL0923399.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            46913..47500
                     /locus_tag="TU818_000552"
     CDS             46913..47500
                     /locus_tag="TU818_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923400.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            47639..>48181
                     /locus_tag="TU818_000553"
     CDS             47639..>48181
                     /locus_tag="TU818_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0923401.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYER"
BASE COUNT        13642 a         9419 c        11268 g        13852 t
ORIGIN      
        1 aaaggaaaat agagcttgac aggggagttt gattattata gaataatagg gtatgtttag
       61 taactgatat cacaaatagc cggctaaacg aatacgaaaa tctatgagga ggtattcact
      121 gtgaaacgta cttatcaacc aagtaagatc cgtcgtcagc gcaagcatgg cttccgtcac
      181 cgtatgtcaa ctaaaaacgg ccgtcgtgtg cttgctagcc gtcgtcgcaa aggacgcaaa
      241 gtattgtcag cataattgca gaatacatca attaaacaaa tcaggagtgc tcgaggctct
      301 tggtttttta attgttcaaa agtgctaaga gcagcttgat gagtgcttat aaagcaggag
      361 ataggagcca aaaagaggct gcttttttaa ttgctcttcc tgaatacgtt ttcaaaaata
      421 acggaaatag ggctaaaaat gaaagtagtt tctaaaacca gaggaagtat tgaaaacgct
      481 ttaatatctg ctacaataaa gatgtgaacg ttctctaaaa ttaataaaag gagtagaaag
      541 catgcttgaa aaaccaagca aggcagagct actggcagct ctgaaggacg ggctgatcgt
      601 ttcctgtcaa gctctgccgg gcgagcctct ctattcagag gcaggaggta tcatgcctct
      661 gatggtaaag gcagcagagg aagcaggagc agtagggata cgagccaatg gtgttcgaga
      721 tattaaggaa atccaagcgg tgacggatct gccaatcata gggatcatca aaaaggagta
      781 tcctccgcaa gcgcccttta tcacgccaac catggcagag gtagatgcct tagcggcctt
      841 aggtgtagcg gtgatagcct tggattgtac gcaaagggag cgtcatgatg gcttagcgat
      901 agtggatttt attcgagcga taagggagaa gtacccagag cagctgttta tggcagacat
      961 cagtacgctt gaatagggtc tagcagccta tgaggctggt atagattttg tagggacgac
     1021 cttatcaggg tatacgccct atagtcgtca ggggacaggt ccggatatgg agctgataag
     1081 tgccttgtgt gatgcagggg tatcagtgat agctgagggc aagattcata gtccagagga
     1141 ggccagggct gttcaggcct tgggagtagc tggtattgtg gttggtggtg ctattaccag
     1201 accaaaggaa attgcagagc gctttgtggc ggctttgaca tcgtcattgt ctataaaaaa
     1261 taattaatat aaaggagaat ttacaatgaa aatgaagaaa ttagcttcat ttgtgatgct
     1321 tggagcatct gttttagggt tagcagcctg tggcagtagc agcaaggagg ctgacaaatc
     1381 agattcagct gctaagacag agatcacctg gtgggccttt ccaaccttca ctcaagaaaa
     1441 ggctgatgat agcgtaggaa cctacgaaaa gaaaattatt gcagcctttg aaaaggccaa
     1501 tccagatatt aaggtcaagc tagaaaccat tgatttcacc tctggtccag aaaaaatcac
     1561 tactgcgatt gaggcaggta cagcaccaga tgtgctcttt gatgctccag gtcgtatcat
     1621 tgagtatggt aaaaacggta aattagctga cttaaatgac ctgtttactg atgagtttat
     1681 caaggacgtc aacaacgata acattatcca agcctctaaa gcaggagata cagcttatat
     1741 gtatcctatc agctcagcgc cgttttatat ggccttaaat aaaaaaatgc tcaaggacgc
     1801 tggtgttctt gaccttgtca aagagggctg gacaaccgat gattttgaaa aggtcttaaa
     1861 agccttaaag gataagggct gcaatcctgg gtcattcttt gccaatggtc agggtggtga
     1921 ccaaggtcct cgtgccttct ttgccaacct ctatagcagc cgcatcacaa atgacgatgt
     1981 gactaagtac accactgatg atgctaattc tgtcaagagc atggagaaaa tcgcaagctg
     2041 gattaaggat ggccttctaa tgaatggctc tcaatatgat ggctcagctg atattcaaaa
     2101 ctttgctaat ggtcaaacct catttacaat cctatggtca ccagcgcaag caggaacaca
     2161 ggctaagctg ttggaagcaa gtaaggttga ttatgttgag gttccattcc catcagagga
     2221 cggcaagcct gaattagaat acctagtgaa cggctttgca gtgttcaaca acaaggacga
     2281 caaaaagatt gaagcttcta agaaatttat ccagtttatc gcagatgaca aagaatgggg
     2341 tccaaaaaat gtggttcgta caggtgcatt ccctgtaaga agctcttatg gtaatctcta
     2401 tgatgatgaa cgcatggcaa tggtttctaa gtggacacaa tactattcac catactacaa
     2461 cactattgat ggctttgctg agatgagaac actatggttc ccaatggttc aggcagtatc
     2521 aaatggagat gaaaagcctg cagcagccct caaagcattc actgaaaaag caaataaaac
     2581 catcgaaaaa gcacaatagt gtgagataaa agtggctcct tttcaatgca catgtccaat
     2641 ggtcactggt aaggagcctt tccttttagg aagattaata gaaaaagagg tatctttgag
     2701 tgaacgtcaa taagttaaaa atgagagaga cactcgtttc atatgctttt ttggccccgg
     2761 tcttggtttt ctttgtggta tttgttttag taccaatgat tatgggcttt gttactagct
     2821 tttttaatta tacgatgaca gactttacct ttgtcgggct tgataactat gtgagaatgt
     2881 ttcaggatcc tgtgtttata aagtctttga ttaataccct tattattgta gttggttcag
     2941 taccaattgt tgttttcttt tcattatttg tagcgacaaa aacctacaat aagcatgtga
     3001 tttcacgttc gttttaccgg gcggttttct tcctgccagt tgtgacaggt agtgttgcgg
     3061 taacagttgt ttggaaatgg atctatgatc ctatgtcagg tattttgaac tatgtgctaa
     3121 agtatgggca tgttattgag caaaatatta gctggcttgg ggacaagcat tgggccttgc
     3181 tggctattat tgtgatttta ttaacaacct ctgttgggca gcctattatt ctttatattg
     3241 ctgcgatggg aaatattgac aattccttag tggaggcagc tcgtgttgac ggtgcgactg
     3301 aattgcaggt cttttggaaa ataaaatggc caagtctatt gccaaccact ctctatatca
     3361 cggtcatcac aacgatcaat tctttccaat gctttgcctt gattcagctg ttgacctctg
     3421 gtggtccaaa ctattcaacc agcaccctga tgtactatct ttacgaaaaa gccttcaagc
     3481 tatcggaata cggctatgct aacacgatgg gggttttctt ggctatcttg atttcactga
     3541 tcagctttgc ccaattcaaa ttcttgggta atgatgtgga atattaaaag gagcttgaca
     3601 tgaggaaaaa gaaattaaca gcatcagata tcctaacaac agccattcta tgtttattaa
     3661 caatattatt tattttcccc ttttattgga tcatgacagg agcctttaaa tcccagccgg
     3721 atactattgt tgtcccacca caatggtggc caaaggcacc tactgttgaa aattttaagg
     3781 ccttgattat tcaaaatccg gctcttaaat ggctctggaa cagtatctat atttctgttg
     3841 ccaccatgct tttggtttgt ggcacctctt ccttggcagg ctatgcttta gcaaaaaaac
     3901 ggttttatgg gcaacgtttg ttgttttcaa tctttattgc tgctatggct ctgcctaagc
     3961 aggtcgtctt ggtgccattg gttcgtattg tgaattttat gggcatccac gatacgctag
     4021 cagcagttat tttgcctttg gtgggctggc cttttggggt attcctgatg aagcaatttt
     4081 cagaaaacat accaacagag ctgctggagt ctgccaaaat tgatggctgt ggtgagatta
     4141 gaaccttctt taacgttgct tttccaatca ttaagccagg ttttgctgcc ttagcgatct
     4201 ttacctttat taatacctgg aatgactact ttatgcagct agtaatgcta acatcaagag
     4261 atcatttgac aatatccttg ggggtagcca ctatgcaggc tgagatggca acaaactatg
     4321 gtttgatcat ggctggtgca gctcttgccg cagttccgat tgttacagtc tttcttgtgt
     4381 tccaaaaatc ctttacccaa ggtatcacca tgggagctgt caaaggttag aaaggtcagg
     4441 agattatgct ctatgatgtc ttggaaaaca ttcgtcgcta caagggtatc catcggcatt
     4501 tagatgtggc cattgacttt ttattgacaa gagatttaag gtcactcaca gatggcaagc
     4561 atgtgatttt agaggataag gtggttctct ttattcagca taattgtctc aataaagagg
     4621 ataatgcctt gtttgaatac cataagcgct atgccgattt gcatctacta gtcgagggga
     4681 atgagcgagt acgctatggc ttaggctaca agcaggaggc tgttagcttt gatgaggcat
     4741 cagacatcgg ctttgtgacc tgcgagagga cttatgactt ggacttggga aatgattgtt
     4801 tttgctattt ctttcccaat gaagctcatc agcctaatgg ctttaacgac gatggtgatg
     4861 cggtcacaaa atgcttgatt aaggtgttga tggaagatta actagaaagg atagggagta
     4921 atgatatgag cagcaaaaaa agaaagctaa tgcagtccat ttttagcttg gatagcaaat
     4981 ggctgagggc tagtgctact atctttgacc ttatcgtgct caatttgctt tttgtgctgt
     5041 cttgcttgcc tgtggtaacg attggcattg ccaaaatggc cttgtatgct agtctgcgag
     5101 attaccggca aggggatatc ggctctgttg taggcgtcta cggctcttat ctacggcggt
     5161 ttgccaagag aggccttcaa ttagggatcc tagaagtgct cttgacgagc tttatcttgg
     5221 ttgaccttta tctcattcag gctcaggtgt cgcttttctt tcaactattt aagattagct
     5281 gtatagcgat attatttgtg gctattatgg tctttttgta tgcttatcct ttagctatgc
     5341 gatatgattt gcctcttatg tcattatttc agcgaagctt tatcttgctt agtcttttct
     5401 tcccctttag ctttgctttt ttagctgtta tgctgctagt ggtctttttg ctgcagctat
     5461 ctccgctaag tctattagga gggctgtcgc ttttagccat tattggcatt agcagcctaa
     5521 cctatcctta tgtcgtcatt atggaaaacc ttcttcaaaa ggtacaactt tattaaaaat
     5581 aagatttaga aaaagagtgt cattatgaaa actttaacca aatatcaagg gattatccct
     5641 gccttttatg cctgctacga tgctgagggc aacatcagtc cagagcgtgt tcgtgctttg
     5701 acacaatatt atattgataa gggtgtccaa gggctttatg tcaatggctc atcaggcgag
     5761 tgcatttacc aaagcgttgc agaccgtaag ttggtcttag agcatgtgat ggcagtagcc
     5821 aagggcaagc taaccattat caatcacgtt gcctgcaaca ataccaagga cagcattgag
     5881 ctggctcagc atgctgaggc cttgggggtt gacgctattg cagcgattcc accgatttat
     5941 ttccgtttgc cagagcatgc tgtggctgct tactggaatg caatttcagc tgctgctcca
     6001 aatactgatt ttgtgattta caatattcct caattggctg gtattgcctt gaccccaagc
     6061 ctctatcagg aaatgctcaa aaatgagcgt gtcataggtg tcaaaaactc ctccatgcct
     6121 gttcaggata ttcaaacatt ttgtgctatc ggaggtgatg atcaccttgt ctttaatgga
     6181 ccggacgagc aatttttagg gggtcgtctc atgggggcct ccgctggaat tggcggtacc
     6241 tatggagcga tgccagagct tttcttacgc ttaaatcaat tgatcaagga caaggaccta
     6301 gagactgcta aggccttgca gtacgctatc aatgatatta ttgggttatt ggtttctgcc
     6361 catggcaata tgtatggtgt tatcaaggaa gtgctgcgca ttaatgagag gctggatatt
     6421 ggctctgttc gttctccttt gccagagtta accgaaaatg atttggtgat ctgtcagcag
     6481 gctgcagcct tgattaagca gaccaaggaa caattttgct cttaaaatga ggtgatcaaa
     6541 tgaagcgtta tcttgctatt gatattggcg gtacagccat caaatatggc cttatgacag
     6601 agacagcaga catactggaa aagcatgaaa tcgccactga ggctcataag ggcggtcctg
     6661 ctattttaga caaggtcaag gacctggttg cgacctatca ggaggctgga ctagctggtg
     6721 ttgcgatttc ttcagctggc atggtggatc ctgataaggg cgaaatcttt tacgcagggc
     6781 cacaaattcc gaactacgca ggcacgcagt ttaaaagggt gattgaagaa acctttggta
     6841 ttccctgtga tgttgaaaat gatgtcaatt gtgccggtct agcagaggct atttctggca
     6901 gtgctaagga ttgccctgta gccctttgct taaccatcgg tacaggaatt ggcggctgcc
     6961 tgctgattga ttcgcaggtt tttcatggca gcagctactc tgcctgtgag gtaggctata
     7021 tccatttgcc ggacggtgcg tttcaggatt tggcctccac aacagctctt gttagagatg
     7081 ttgctagacg tcatggagat gctgttagcg attggaatgg tcgtcgtatt tttgaagagg
     7141 ctaaggcagg taaccaccat tgtatagcag ccattgacca gttagttgac tatctagctt
     7201 aagggcttgc caatatctgc tatgttgcta atccaaatgc tattgtctta ggcggtggca
     7261 ttatggctca aaaggactat ttgcaggata aaatcctagc tgccctcaat aattatctgg
     7321 tacctagcat cgcagaaaaa acccagcttc gatttgccag ccatgaaaac aatgctggta
     7381 tgattggggc ttactaccat ttcaagcata aggagcaagt ctaatgatag aaaccatgtc
     7441 acttgaagag atgatgtcct acagggggcg tcacgaggtg cccaaggatt ttgatcattt
     7501 ttgggagacc tgtatcaagg aaaatcaagc tgcctcttat cagcttgatc aaaaggattt
     7561 tggccttgat tttgctgatt gctatgagtt gcgcttcaaa gggagtaatg gctcaacgat
     7621 ctatgccaaa tgtgtctttc caaaagccaa gcagctagtc ccagttgtct tttattttca
     7681 tggctaccag ggtcagtaca cagctagcta gggtcattga ggtgcttttt tgtgatgcta
     7741 tttatctgaa ggattgataa tcgtctcttg gaaaattttt gttttgcctt ccttgttgat
     7801 ttctaaaaaa taagcgtaga taatatccgt tacaaagagc attggaaatt gtggggagat
     7861 acgattgcca tagttaaggt gacgagcagt agcgatatgc acaatttcgt caagctggta
     7921 agggatttca tcggtctggg ttgtgagcag cactgtcttg gcaccgcgtg tcccagcggt
     7981 ctgcaaagcc tctaagacgg acgctgtttg agcagagagc gaaaaaccaa taaccaagca
     8041 tttgtctgta atgctgctgt taacccaggt gaagctatca gtgtcatcta aggcctcgca
     8101 aataacacca agtcgcatca gacggagctt gaattctttg gcggcaagag ctgagctgcc
     8161 cttaccgtaa aaataaatcc gctcagcatt ttcaatccat tgcgcaatgt cttgtagctg
     8221 cttttcattg atcagctcgg tagccttttc gatcaattca cggtagttca taaggacctt
     8281 tttagtgttg taattttgca ggttgggtgc cttttgatcc attgcctcgc gacttttttg
     8341 gcattcaaag ataaattcgc gataaccggt aaagccacat tttttggcaa agcgtgtcaa
     8401 ggctgcctgt gagacatgaa gccttttaat catgtctgaa gctgttagct cttcgacctt
     8461 taggtctgtt tccataaaaa attgagcgat gcttttttct aagctcgtca tgctgtctag
     8521 tgcagcttcc attttgctga ttaaacggtg attgtgtatc atatgaactc cctgatgtaa
     8581 ggctgtctat tataatagta tatcataaaa aggaaaaaga taaagaatac agataatata
     8641 ataatataga gctgatatta cagttatgtc aaggctgact gtttgagtaa accaagagct
     8701 atgctaagaa tgaagtagct gatgagatat ggtataataa tcaagcaggt atccctttta
     8761 gggcaataca agaaagagga atgactaaga atgatagaaa tttttgatac ccatacgcat
     8821 ttgaatgtgg atcattttag tggtaaagag gaagaggaat tagcacttgc taaggagttt
     8881 ggggttagct accataatgt cgttggcttt gatcaggaga ctattgatca agcccttacc
     8941 ttagctgatg cttataggga ggtctatgca acgattggct ggcacccgac tgaggctggc
     9001 tcttacacac aggcggttga agatagtctg attgcttgct tgaagcaccc aaaggttgtt
     9061 gccttaggag agattggctt ggattactat tggatggagg accccaagga ggtacagata
     9121 gaggtcttta agcggcagct acagcttgct aaggaccatg acctcccctt tgtggtgcat
     9181 acgcgtgatg cccttgagga tacctatcag gtcttaaagg aggctggagt gggtcctaga
     9241 ggtggtatca tgcattctta ctcaggatca cttgagatgg ctcaacgatt tgtagatctg
     9301 ggtatgctga tttccttttc aggggttgtc acctttaaaa aggcggttga tgttcaggaa
     9361 gcagcaagac acctgccgct ggataagctc ttggtggaaa cagatgcccc ctacctcgcc
     9421 ccagtaccaa agagaggacg tgaaaaccat accgcctata cgcgttatgt tgttgagaaa
     9481 atcgcggagc tacgtggttt atcagtagaa gagatagctg cagcaacgac tgccaatgca
     9541 aagagggtgt ttagaattga ctgagaagct taaaattcaa gaggttattg tggtagaggg
     9601 gaaggacgat accgctaatt tacagcgctt ctatgatgtc gatacctatg aaacaaaggg
     9661 ctctgccatc actgatgagg acttagaacg cattgatcgg cttaacaagc tgcgtggtgt
     9721 gattgtcttt acggatccag attatcatgg cgagaggatt cgcaaactga ttatgagagc
     9781 tgtcccaaca gctcgtcatg cctttttacg tcgacatgag gctaagccaa ggtccaaaag
     9841 taagggacgt tccttaggtg tggagcacgc tagctttgag gacctgcaaa aggctctgtc
     9901 tcaggttacc cagtcttttg atgacgagag ttattttgat attagtcaga cagatttgat
     9961 tcgtctaggg cttttattgg cagctgatag ccgcaagcgc agagagtatc taggagaagt
    10021 ccttcgtatc ggctattcca acggaaagca gctcctaaag cgcctaaagc tatttggcat
    10081 taccctatca gaggttgagg acgtgatgac ctcctatcag actgagcaat agatggcgct
    10141 agaaaggctg attggatcaa acaaaagagc cctgagactt cttgttctgg ctccaaaaaa
    10201 ttagataaga aatggtaaca aggattgaat tctgtattgg gcaggagtca gtccttttaa
    10261 ctttcttaga taagcattct ctgttctaag acgttcattc tccttgaagt tgctctagtt
    10321 ctccagatgt tctttgattg atgtcctctc ttgcttggtt tccctcttgt tttatcaaga
    10381 atagtataac cattttcatc tctttttttg ctgtggctct gataaataat agaaatatgc
    10441 tacaatagat ataaaacaat gaataggaca tcaacatgag aattgcagat tacagtgtaa
    10501 ccaagtctat ccttgatcgc tatggtttta cctttaaaaa atcatttggt caaaatttct
    10561 tgacggatac taatatttta cagaagattg ttgatacggc tgagattgac aagtcagtca
    10621 acgtcattga gattggtcct ggtatcgggg ctttgaccga atttttggca gaaagggctg
    10681 cagaggtcat ggcctttgag attgatgagc gcttggtgcc aatactggct gatacgcttc
    10741 gtgattttga caatgttcag gtggttaatc aggatatttt aaaggcagat ttacagaccc
    10801 agctaaagca atttagcaat ccggaccttc ctatcaaggt ggtagccaat ttgccctatt
    10861 acatcactac acccattttg atgcacctga ttgaaagtaa gattcccttc caagaatttg
    10921 tcgtcatgat gcagcgcgag gtggcagatc ggatttcagc tgagcccaat accaaggcct
    10981 atggctcttt gtctatagca gtccagtatt atatgaccgc taagatagcc tttgttgttc
    11041 ctaggactgt ttttgtgcca gcaccaaatg tggattcggc aattctgaag atgactcgtc
    11101 gtgaccagcc cttgattgag gttcaagatg aggatttctt ttttagggtg tcacgagtag
    11161 gctttgtgca tcgcagaaag acgctttgga ataacttggt tagccatttt ggcaaggctg
    11221 aggacacaaa ggcaaggctt gagcagggac tagctctagc tggaatcaag ccttctatcc
    11281 gaggagaagc gctgtctatt caagattttg gacggttagc tgatgcccta aagcaagtag
    11341 gcttctagtg ccttagttat gattgtagct tgtcacagca atcctgctgt ggctttttta
    11401 gatagtggtg ggttcatctt atctttggtg aaacttgggc taaactgctg aattcgaatg
    11461 atttttctga tataatggca ttattctagg ataaaaaaag gagttcattt gcaaggcaaa
    11521 atcattaagg ctctggctgg cttttactat gttgagtcag aggggcaggt ttatcaaacg
    11581 cgggcgcgtg gcaattttag aaagcgtggt caaacaccct atgtaggaga tttagtagaa
    11641 ttttctgctg aggacaattc agagggctat attttagcta ttgctgagcg gaaaaatagt
    11701 ctggtgcgtc ctcccattgt caatattgat caagcagctg tcattatgtc agccaaggag
    11761 cctgatttta ataccaacct tttagatcgc tttctcattt tacttgagca caaggccatc
    11821 caccctatta tttacatttc aaaaatagac ctgcttgagc agccagagag tatcgaagcc
    11881 attggtcagc attatcgtgc gattggctat gattttgtga cgagcttatc acatctgctg
    11941 ccattattag ctggtaagac aacagtattt atggggcaga caggagttgg aaagtccact
    12001 ttgctaaacc gtatcgcacc agagctagct cttgaaacgg gtgatatttc agacagtctg
    12061 ggacgaggac gccacaccac tagagctgtt agcttttatg acgcttataa tggcaaaatc
    12121 gcagacaccc ccggcttttc gtccttggac tatggcattg ataatgctga ggatctcaac
    12181 gaagcctttc cagagcttag acgccttagc catagctgta aatttcgctc ctgtacccat
    12241 actcatgagc ccaagtgtgc ggttaaggaa gccttgggaa atggtgagct ctggtctgtt
    12301 cgctatcaga attaccttca atttctgagt gaaatcgaaa accgtcgaga aacatatcaa
    12361 aaagttagta aaagaaagta ggtttaacta tgtcatctct gaaaattgcg ccatctattt
    12421 tagcagccga ttatgcttgc tttgctgctg agctggctcg tattgaaaaa acagatgctg
    12481 aatacgttca tattgatatc atggacggtc agtttgtgcc aaatatcagc tttggagcag
    12541 atgttgttgc tagcatgcgc aagcacagca agctagtctt tgattgccac ttgatggttg
    12601 tgaatcctga gagatatgtt gaggcctttg ctcaggcagg agctgatatc atgaccattc
    12661 atgtggagag cactcttcat agtcatggcg ccttgcaaaa gatcagggct gccggcatga
    12721 aggctggtgt ggtcattaat cctgggacac ctgtctctgc ggttgagcct ttattaagct
    12781 tggtggatca ggtgctgatc atgactgtta acccaggctt tggaggacag gcctttattc
    12841 cggaatgtct ggaaaaggtt gcagctattg ctaaaatgag agatgaaaga ggcttgagct
    12901 ttgatattga ggttgacggt ggtgttgatg ataaaaccat tcgtgcttgc tatcaagcag
    12961 gagctaatgt ttttgtggct ggctcctatc tgtttaaggc agcggatttg gcagctcaag
    13021 tgcaaacatt gagggcggcc cttaatggtt aaggtagccc tctttgcagg tggggatttg
    13081 tcctatttta cctgtgattt tgattatttt gttggaattg atagaggaag tctatttttg
    13141 ttagaaaatg ggcttccttt gaatatggct gtaggcgatt ttgattcaat tccccaagta
    13201 gcctttgagg ttgtcaagga gcaagcagag cttcttgttc aggctagtcc tgaaaaaaat
    13261 gatacggaca ctgaattagc tctcaaagag gtatttaccc gttttccaga ggcagaggtt
    13321 acgatctttg gtgcttttgg cggtagacta gaccacttgt tatccaatgt ctttttacca
    13381 gcggatccag agcttgcacc gtttatggca caaatttgcc tgcgggatca gcaaaatgcc
    13441 attagctatc gatcctctgg ctggcagacg attaggcagg ataaggacat gacttatgtg
    13501 gcctttatgg ctgatggtga tgctgacttg accattacag gtgccaaatt tgatttgacg
    13561 acgtccaatt tctttaagaa aaaggtatac gctagcaacg agttcattga tcagcctatt
    13621 aaggttcatg tgccaaaggg ctatttaatt attattcaga gcaaagatag gagttagtat
    13681 ggaccttatt cttttcgtgt tagtgcttgt gttgatagga cttgctgcct attcatttgt
    13741 tagcataaag catttgcaga gcagattaga aaaagcctta gacgataatg ctgataatct
    13801 atcagatcag ctaacctacc agctggatat ggcaaataag agtcagctgc tagagctatc
    13861 aacagtgatg aatcgtcagc aaaatgagct ttttcagcag ctgatggtta ttcgtgatac
    13921 gctgcatcag ggcttggctg aaaatcgcga ccgctcagac cagcgtttgg aaacgatgac
    13981 tcaaagcctt agccaagctg tcaagaacct acaggattct aatgaaaagc gactggagga
    14041 aatgcgccat acagtcgaag aaaagctaga aaagacattg aagaatcgat tgcaaacctc
    14101 ctttgaggcc gtttcaaagc agctagaaag cgtcaatcag ggtctaggag aaatgcggac
    14161 cgtagccaaa gatgttggta ccctaaacaa ggtcctatcc aataccaaaa ccagaggaat
    14221 cctaggtgag ctccagcttg gtcagattgt tgaggacatc atgacagcta accagtatga
    14281 aagagagttt gccacagttt ctggctcaag cgatcgtgtc gaatacgcta tcaagctacc
    14341 tggaaatggg caaggagact atatttacct acctattgac tccaagtttc ccttggagga
    14401 ttattacagg ctggaggacg cctacgaggc tggtgataga gctgctattg agactagccg
    14461 aaaggctctt cttgcggcga ttaaacgttt tgctaagagt attcatagta aatacctgaa
    14521 tccacctgaa acaaccaatt ttgggattat gtttttacca accgaggggc tctactcgga
    14581 ggtggtgcgc aatccggctt tctttgatag ccttcgtcgc gaggaaaata ttgttgtagc
    14641 aggcccatca accttatcag ccctgcttaa ttccttatct gttggcttta aaacccttaa
    14701 cctgcaaaaa aacgcagacg atattagcaa gattttaggc aatgtcaaat tagaatttga
    14761 aaaatttggc ggcctgcttg ctaaggcgca aaagcagctc aacactgcta accataccct
    14821 agaccagctg atgtcaacca gaaccaaagc gattgttcgt gctctggcta ctgtcgaagg
    14881 ctaccaagac cagtcaaccc aatccttatt acatataccc ttattagaag aggcagacga
    14941 tgaagattaa ccaaatgaaa aaagaccagc cttttgaagg cttttacctg ataaaatcag
    15001 cagaagtcag aaaaacaagg gctggcaagg attttattgc ttttaccttt caagatgata
    15061 ctggtgagat ttcaggtaat ttgtgggacg cccagcccta taatgttgag gaatttgtcg
    15121 caggtaagat tgtctttatg aaaggccgtc gtgaggtcta taatggcact cctcaggtta
    15181 accagattac cttaagaaat atccggcctg gggagcctaa tgacccaaag gaatttaaag
    15241 aaaaggcacc tgtcagtgtt actgaggttc gtgactacct agatcagatg ctctttaaga
    15301 tcgaaaatgc gacctggcag aggattgtca gagcgcttta ccgcaaatat gataaggagt
    15361 ttttcactta tccagcagcc aaaaccaatc accatgcctt tgaatcaggc ttggcctatc
    15421 atacagcaac gatggttaga ctagcagata gcattggaga tatttatcca gagctaaata
    15481 aaagcctgtt atttgcaggc attatgctgc atgacctagc caaggtactt gagctgacag
    15541 gcccagacaa taccgaatat actatccgag gcaatctgat aggacatatc gccctcatca
    15601 acgaagagat tacaaagacc atcacagagc tgaacattga tgacaacaaa gaagaggtca
    15661 ccgttttacg ccatgtaatc ttaagtcatc atggccaatt agaatacggc agccctgttc
    15721 gtccgcgcat tatggaggca gagattattc acatgattga caacattgac gccaatatga
    15781 tgatgatgtc aacagctctc agtcgtattg gcgagggaga aatgaccaat cgtattttcg
    15841 ctatggataa ccgatccttt tataaaccta aatattagca aggatcataa taaaaaacga
    15901 acattttgca gttgaatgtt cgttttttcg ttatgttatg atataatagt agagaatata
    15961 taaataatgg ggaacatatg aaattaagac gaagtgaacg catggttgtg atatctaatt
    16021 acctgattaa caacccttat aagctaacaa gtttaaatac ctttgccaca aaatatgagg
    16081 cagccaaatc atctatttca gaagatattg ccattatcaa aaaagccttt gaagaatcta
    16141 atattggaga gattgacact ctaacagggg caagtggagg tgtcattttt acgccaagca
    16201 tttcagaggc agaggctcgc tcaatcgtag aagagctgtg tcagcggctt tcagaaagta
    16261 accgcatttt acctggtggc tatatctatc tgtctgattt attaagcaca ccaaagctct
    16321 tgcagaatat cggtcgcatt atcgctaatg cttttaaggg gcaaaaaatt gacgcggtga
    16381 tgacagttgc aactaagggg gttcccttgg ctaatgcggt tgcaaatatt ctgaatgtac
    16441 cctttgtgat tgtcaggcgc gacttaaaaa tcacagaagg ttcaaccgtc tcagtcaact
    16501 acgctagtgc ctcaagttat cgtattgaaa aaatgttttt atcaaagcga agcttaaagc
    16561 caaacagtcg agtcttgatt gttgatgatt ttttaaaggg tggtggtaca atcacaggca
    16621 tgatgagcct gttaacggag tttgatagta cattggtggg tgtagctgtt tttgcagaaa
    16681 atgcacaatc agagcgcgaa caaatgtcct tcaagtcact attaaaggtc tccgaaattg
    16741 atgtcaaaaa taatagggtc gttgttgaag taggaaatat tttcgataaa taaatcgaac
    16801 gtaggtggaa aaataaaagg ggattaatca tggagcaaga aaactcaaga acaaagcatg
    16861 ttaaaagtac cattgctttg acatcaacca ttgccctatt agggacaagc gttggtgtat
    16921 cacatcaggt aaaggcagac gatgctaagt caggcgatgc caatacaagc aataccagcg
    16981 aagctacgct agctaagcca gaaacgcttg aggaggcagt ccttgcggta aaggctacag
    17041 aagaaacact cagtgagcgt aaaaaagaat tagctgagac taatacaaat atcgcggaaa
    17101 cagagggcga aatcgcaaac ctagaagcaa ctaaaaaaga acagatagct gagcttgcca
    17161 aggctgagga gctacttgag acttactcgt ccatgagtga ggaagaccta gccaagtcaa
    17221 ttgaaaagca tgagacagag ctagagacaa ttaacacaga actagagaag gcgactactg
    17281 agagtcaagc tcaggcagag gcagtggcta agcagcaaga aacgatcgca gcagaggcta
    17341 caaaggccga ccagctagct acccagctaa cagcagcaga gcaaaaggtc tcagacctta
    17401 acacgatgat tagccagccg gaagctattg tctcagaagc tcaagctgca aaagaagagg
    17461 tcaagcgcat ttctgatgac ctagcaaagg ctacagcaaa tctagctact gttaaggaga
    17521 cagtccacag ccagctaacc tcagacctag cagccaacaa ggcagccctg gcagctaaag
    17581 aggcagagct gcaaaggctt caaaatggag ttgccactgc ccaattgaac gttgctggca
    17641 gcaataaatt aattcttcca aaagactacc caattgagga gattaaaaag ctagcagcca
    17701 gtggttatat cggaacagca gcatataatc aatattatca ggcagttaag gatacaatga
    17761 ttgcaaaggc agagccgggt gctgccatga atcagtatgt tgatattcct gaggacctca
    17821 atcgtgttgt tgaccctgac aacctatcac aagaggttca aaatgagcta gctcagtttg
    17881 cagctcaaat gattaatgat gtccgcaagc agctaggact tgtccctgta acagtaacag
    17941 tcggctcaca ggagtttgct cgcctgctaa ccaagagcta caaggaaaca catcaaaata
    18001 ctcgaccttc ctttgtctat ggacaagtag atgcttcagg tcatcgcggt gtaggtccgc
    18061 atgatcaaac gattattgaa gaatctgctg taaaggtagg acttcgtcaa aaagatgaca
    18121 acatgtacga aaaccttggt gcctttaacg aggttcacac tgtcaacggt atcaagcgcg
    18181 gcatctatga cagcattaag tatatgctgt ttacagatca cctgcatggg aacacctatg
    18241 gtcatgctgt taacttcctg cgtgttgata agactgaccc taatgcacct gtttacctag
    18301 gattttcaac aagtaatgtt gagtccttaa atgagcattt tgtgattttc ccagagtcag
    18361 atattgtgga cgctactcgt tttagcacga ctgaaattcc aaaatcaggt caggtgattg
    18421 atcgctcagc aagcatacag gcattgacaa atgatattgc ttcgatcaag ggcaagattg
    18481 cgtctcttga aagcagatta gctgatcctt cctcagaagc tgaggtcaca gctgcgcagg
    18541 caaaaatcag tcagctgcaa catcagctag aagcagccca agccaaatct cataaattgg
    18601 atcaacaggt tgagcaattg gccaatacaa aagattctct acgcacacag ttgcttgctg
    18661 ccaaagaaga gcaggcacaa ttgaaggcta atctagataa ggccttggcc ttgctagcgt
    18721 cttcaaaggc tacgcttcat aagcttgaag cagctatgga agaggctaag gcaagagtag
    18781 ccggcttagc tagtcagaag gctcagcttg aggatctgct agcctttgag aaaaatccta
    18841 atcggatcga gcttgcacag gaaaaggtag ccgcagccaa aaaggcttta gctgatacag
    18901 aggataagct cttagctgct caggccagcc tgtctgattt gcaggctcaa agagcaagac
    18961 tccagctttc tattgcgaca attgaacaac aattagtact attgaagaat ttagtccaag
    19021 aaaagcaaag gctcagactt gaggctgaaa ggctaaatag catgtcagaa acaagacagc
    19081 ttctcaatca gctagcgccg caggctgcaa aagcaggtgt cggctcagaa ttggttgcta
    19141 caggtcttct tgtctccaag gttgcctcag ctatcgctaa gcaatcaccg acaagccatt
    19201 cctatggagc aggagcagca tcacatgcag ctgttgatga caacacacag cgtgctgttc
    19261 aggctggtat ggtcatgctg gcagctgccg gcttagcaac ggttaagctc aaaaaaggca
    19321 gcaaaaaacg ctaagcctag cttaaaaagc atttgacaca aggtatcgtc tatgttatta
    19381 tattagacgg tactttttac ttttggtctc tcaagagtgt acagagacgt gctgacaatt
    19441 gttgcaaaaa gtgcaccaga tataggctgt caccaagtgc tatatcaacc aaaattaaaa
    19501 aaacaggaga atgtagatgc ctacaattaa ccagttggta cgtaaaccac gtaaatctaa
    19561 aattgagaaa tcagattcgc cagctttgaa cattggctac aacagtcata aaaaagttca
    19621 tacgaagctt gctgctccac aaaagcgtgg tgttgcgact cgtgttggaa caatgacacc
    19681 taaaaaacct aactcagccc ttcgtaaatt tgcgcgtgta cgcttaagca accttatcga
    19741 agtaacagct tatatcccag gtattggcca caacctacaa gagcacagtg ttgtgcttat
    19801 ccgcggtgga cgtgtaaagg accttccagg ggtacgctat catatcgttc gtggagcact
    19861 tgatactgca ggtgttgcag accgtaagca aggccgttct aagtacggtg ctaaacgtcc
    19921 aaaaggataa tagaggaggg ataagaaaca atgagtcgta aaaatagagc gccaaaacgc
    19981 gaagtattac cagatccatt atataactca aagcttgtga cgcgtcttat caatcgtatt
    20041 atgcttgatg gaaaacgcgg aactgcatca tcaatcgttt atgatgcttt tagcgaaatc
    20101 aaagaagcaa caggcaacga tgctcttgaa gtatttgaaa cagctatgga caacatcatg
    20161 cctgtgcttg aagtgcgtgc acgtcgtgtc ggtggttcaa actatcaggt tccagttgag
    20221 gttcgtccag agcgtcgtac aacacttggt cttcgttggt tggtaactgc atcacgtgct
    20281 cgtggtgaac acactatgaa agatcgtctt gctaaagaga ttatggatgc tgcaaacaac
    20341 accggtgcgt cagtcaagaa acgtgaggat actcataaga tggctgaggc taaccgcgcc
    20401 tttgcacact tccgttggta agaataagat acgaaggtgt acagaacgca tagtgaagat
    20461 aggaagcttg acgaagagat ttttatctct aggaaagctt atctttttca cacagcgttt
    20521 agcctgagtt cagttttagg ctgttttagt gtgagacaaa tgctagccca aatcgggaaa
    20581 ttgacgcaga agcgatcatt tccagaagat tttatctttt tggcagacat ttgtcgctaa
    20641 aattcaacta atctaagatg tgagagtgtt aagcaagttc tagacaaact gatctattat
    20701 cttttttgtc agtgacttgc agctcaaact cagttacaat caagatgtat agacaaagag
    20761 agcaagattt taatagaaaa ttctcacctt caagatgagt tattgttttg atcggattgc
    20821 tcttaagtcg ggttttggtt tgcaaacata ctaaatgcta tctatcaaac atatcttagg
    20881 aaacgggtag gcctctgcct atccgttttt aatgaatagt gttataataa gatgtaaata
    20941 aaaaatatag gagaaaaaac ctaatggctc gcgaattttc actagcaaaa actcgtaata
    21001 tcggtatcat ggctcacgtt gatgctggta agacaactac aacagagcgt atcctttact
    21061 acaccggtaa aatccataaa atcggtgaaa cacacgaggg tgcatcacaa atggactgga
    21121 tggagcaaga gcaagagcgt gggatcacaa tcacatctgc tgctacaaca gcgcaatggg
    21181 atggacatcg tgttaatatc attgacacac cagggcacgt ggacttcacc attgaagtac
    21241 aacgttcgct ccgcgttctt gacggtgcag taaccgttct tgactcacaa tcaggtgttg
    21301 agcctcaaac agaaactgtt tggcgtcaag caactgaata cggtgttcca cgtattgttt
    21361 ttgccaacaa gatggataag atcggtgctg acttccttta ctcagtacaa acccttcacg
    21421 atcgtcttca agcaaatgct cacccaattc aattaccaat cggttcagaa gatgattttc
    21481 gtggtatcat tgacttgatc aaaatgaagg ctgaaatcta caccaatgac cttggtacag
    21541 atattcttga agaagatatt cctgaggaat acctagagca agctcaagaa tatcgtgaaa
    21601 agcttatcga agcagttgct gaaactgacg aagatttgat gatgaaatac cttgaaggtg
    21661 aagaaatcac taacgaagaa cttgttgctg gtatccgtaa agcaacgatc aacgttgagt
    21721 tcttcccagt gctttgtggc tctgccttca aaaacaaagg agttcaattg atgcttgatg
    21781 cggttattgc ataccttcca agcccacttg acattccagc aattaaaggg gttaatcctg
    21841 atactgacgc tgaagaagag cgtccagcat ctgatgaaga gccatttgca gcccttgcct
    21901 tcaagatcat gactgatcca tttgtaggtc gtttgacctt cttccgcgtt tactctggtg
    21961 ttcttaacag tggttcatac gtgatgaata cctcaaaagg taagcgtgag cgtatcggac
    22021 gtatccttca aatgcacgct aacagccgtc aagaaattga aacagtttac gctggtgaca
    22081 ttgctgctgc tgttggtttg aaagacacta caactggtga ctcattgact gatgaaaaag
    22141 caaaaatcat tcttgagtct attgaggttc cagagccagt tatccaattg atggtagagc
    22201 ctaagtctaa ggctgaccaa gataagatgg gtattgctct tcaaaagctt gctgaagaag
    22261 atccaacctt ccgcgttgag acaaacgttg agactggtga aacagttatc gctggtatgg
    22321 gtgagcttca ccttgatgtc cttgtagacc gtatgcgtcg tgaattcaag gttgaagcta
    22381 atgtaggtgc tcctcaggta tcttatcgtg aaaccttccg cgcttctaca caggctcgtg
    22441 gcttcttcaa gcgtcagtct ggtggtaagg gtcaattcgg tgacgtttgg attgaattta
    22501 cgccaaatga agaaggtaaa ggatttgagt ttgaaaatgc cattgtcggt ggtgtggttc
    22561 ctcgtgaatt tatcccagcc gttgaaaaag gcttgattga gtctatggct aatggtgtcc
    22621 ttgcaggata cccaatggtt gacgttaaag ctaagcttta cgatggttca taccatgatg
    22681 tcgactcatc tgagactgcc ttcaagattg cggcttcact tgcccttaaa gaagcagcta
    22741 aaacagcaca gccagctatc cttgagccaa tgatgcttgt tacaatcaca gctccagagg
    22801 ataatcttgg agatgttatg ggacatgtga cagctcgtcg tggacgtgtt gatggtatgg
    22861 aagcacatgg tactagccaa attgttcgtg cttatgtgcc acttgcagaa atgtttggtt
    22921 atgcgactgt tcttcgttct gcaacgcaag gacgtggtac attcatgatg gtatttgacc
    22981 actatgagga tgttcctaag tcggttcaag aagaaattat caagaaaaat aaaggtgaat
    23041 aatcacccct aagaggctgt ggatagtatc ccagcctttt tgatgtgtta caacagatgg
    23101 gcggtgcagc aattgatcaa agcaatgaca gaaaaatcaa gccctatcag gcataaacgt
    23161 ttaggaaaag gccttaagaa agcgctttta acaacattaa gcgacacttt tggctgccct
    23221 aaaaagctct ttgctgtctc aatattgatg gagaagcagt cttttgaaaa tgggtaatat
    23281 gtttgcattt tttctgaaat agttatataa tagttacgtt gaagggttgt tgcaggaatc
    23341 tgcaagttaa tcttttcaca ataggtaggg attagtccct ttaataataa ttcttttgat
    23401 tttcataagg aggaaatcac taatggtagt taaagttggt attaacggtt tcggtcgtat
    23461 cggtcgtctt gcgttccgtc ttatccaaaa tgtagaaggt gttgaagtaa ctcgcatcaa
    23521 cgacttgaca gatccagcca tgttagcaca tcttttaaaa tatgattcaa ctcaaggacg
    23581 ctttgatggc gacgttgaag tagtagaagg tggatttaac gttaacggta aatttgttaa
    23641 ggtttctgct gaagctaacc ctgaaaacat tgactgggct tcacaagaag tagatatcgt
    23701 tttggaagca actggtttct tcgcttcaaa agctggtgct gaaaagcact tacacgctaa
    23761 tggtgctaag aaggttgtta tcactgctcc tggtggaaac gatgttaaaa ctgttgtttt
    23821 caacactaac cacgaaattc ttgatggtac tgaaacagtt atctcaggtg cttcatgtac
    23881 aactaactgt cttgccccaa tggctaaagt tcttcaagac aaatttggtg ttgttgaagg
    23941 cttgatgaca actatccatg gttacactgg tgaccaaatg actcttgatg caccacaccg
    24001 taagggtgat ttccgtcgtg cacgtgctgc agctgtgaac attgttccta actcaactgg
    24061 tgctgcaaaa gctatcggtc ttgttattcc agagcttaac ggtaagcttg acggtgctgc
    24121 acaacgtgtt ccagttccaa caggatctgt tactgagtta gtatctgtac ttgaaaaaga
    24181 cgttacagct gacgaagtga atgctgcaat gaaggctgct gcaaacgaca gttttggtta
    24241 cactgaagat caaatcgtat caagcgacgt tgtaggtatc cactatggtt cattgtttga
    24301 tgcaactcaa actaaggtat tgacagttga tggtaaacaa ttggttaaaa ctgtttcatg
    24361 gtatgacaac gaaatgtcat acactgctca gcttgttcgt acacttgagt actttgcaaa
    24421 aattgctaaa taatgactag agggcctagt ttacctaggc tcttttttgt gtcatgataa
    24481 aggttgctta tccctcattg gctagcttat tgctgaactt gcacttaggc ttaagctgca
    24541 cataggataa gtttttttgc taacgcttta gtgattagct gttctcagag agggtcattt
    24601 tagaaacctt cttaaggtga tatggctatc aagctgcctt ctttgaactg ctatgcttag
    24661 gctttgagtt taggtcttaa aagctttagg tgagtttttc gttataatta actgcataaa
    24721 gcatggcttt aagctcattt ccagcgcaaa tacctttttt ctttgcaaga tgtcaaagag
    24781 aagtactgta atggctcggg cttatctaca ttttttgctc agctattttt agctgttttt
    24841 tagctatggc tccatgaaat tgtgaagcgt tttcattttt attggttata gtcttgacaa
    24901 tctgaaatga tggtaataaa atgagaggtg gataaataac cgtacttaat aatgtatgga
    24961 atattaggag gattttatga catctaaaaa aattcttaac cttgtgtctt tagggttatc
    25021 gttggtttta atctctggct gtacgacaaa tggagagaaa aaagcagctc ctagtcaaga
    25081 caaggataag caagaaaagg ttgtccgtct aaccaatgat cagctaaggg ctagggaaaa
    25141 taccatggcc acactctggt atcagcagtc tgaagaggct aaggctctct acttacaggg
    25201 gtaccaagtg gctaagcagc gcttagatac attattgagt caagcaactg ataaaccata
    25261 ctctattgtt ttggacattg atgagacagt gctcgataat agtccttacc aggctaaaaa
    25321 tattaaagag ggcacaggct ttacgccgga ttcttgggat aaatgggtcc aaaagaaatc
    25381 agccaaggca gtagcaggtg ctaaggactt cttgcagtat gcaaatgaca agggcgttca
    25441 gatttactat gtttctgaca gaacgactaa gcaagtagag ccgactatgg aaaatcttga
    25501 aaaagaaggt attccagtgc aaggcaagga tcatttcttg ttcttagagg agggtgtaaa
    25561 atcaaaagag ggccgtcgtc aaaaggtgca agaaacaaca aatctagtgt tgttatttgg
    25621 tgacaatttg cttgattttg cagagttttc taagacctct catgaagata gaagaaagct
    25681 tttggatcag ctgcatgcag agtttggcag caagtttatc atcttcccta atccaatgta
    25741 tggatcatgg gaaagcagtg tctataatgg tcaaaaatta gacagtgaag gccaaatcaa
    25801 agcacgtgac aaggctttag aggcttatta aaagccctga tttgcgtgat tgctatgact
    25861 atgttgtggc ttcctgcctg cttaggtgat tgtgatctgc taaaaagagg tttacccaag
    25921 ggatttttca agcgctttga aaaattgtga aatagttaat ttattgtttt cagattttat
    25981 ccttatcaaa agaattgtgt tataatagag tgtactaaaa aatattaagg agtctatgaa
    26041 atggctaaat tgactgttaa agaccttgac ctaaagggta aaaaagtgct cgttcgcgtt
    26101 gactttaatg tccctttgaa aaatggtgtt attacaaacg ataaccgtat ttctgcagca
    26161 cttccaacaa tcaaatacat tattgagcat ggtggtcgcg ctatcctttt ctcacaccta
    26221 ggacgtgtga aggaagaggc agacaaggaa ggcaaatcat tggcgccagt agcgaaaaac
    26281 ttggctgaaa agcttggtca agaggttatt ttccctggta gcactcgtgg ggcagagctt
    26341 gaagctgcta ttgatgctct tgaggatgga caggttcttt tggttgaaaa cactcgcttt
    26401 gaggatattg acggtaaaaa ggaatctaaa aacgatccag agcttggtaa atactgggca
    26461 tcactaggag aaggaatctt tgttaatgat gcctttggta cagctcaccg cgctcatgcg
    26521 tcaaacgttg gtatctctgc aaatgttgaa aaagcagtgg ctggtttcct tcttgaaaat
    26581 gaaattgcct atatcaagga agctgttgag actccagagc gtccatttgt cgctattctt
    26641 ggtggttcaa aggtttctga taagatcggt gtgattgaaa accttcttga aaaagctgat
    26701 aaggtgctta tcggtggtgg tatgacctat accttctaca aagctcaagg tattgaaatt
    26761 ggaaactcac tttgtgaaga ggacaagctt gatgtggcaa aatcacttct tgaaaaatca
    26821 aatggcaagc ttgttttacc agttgattcc aaagaagcaa acgcttttgc agattacact
    26881 gaagtgaagg taactgaggg tgaagcagtt gatacaggct tccttggtct tgacatcggt
    26941 ccaaaatcta tcgctaaatt tgatgaagcc ctgacaggtg ctaaaacagt tgtttggaat
    27001 ggtcctatgg gtgtctttga aaaccctgat ttccaagaag gtacaattgg tgtgatggac
    27061 gctattgtga agcagccagg tgttaagtca atcatcggtg gaggtgattc agcagcggca
    27121 gccatcaacc ttggacgtgc agataaattc tcatggatta gtacaggtgg aggtgcttca
    27181 atggagcttc ttgaaggtaa ggagcttcca ggcttagcag ctcttacaga aaaataagct
    27241 gataccattt cggtgctgtc agtcgcaggc tgctatatgg tctgttaagg gctaagacag
    27301 ctgaaggctc acaaaggtgg cttatgttgc tggcggtgct tatgctaatt gttatgatta
    27361 acaagctgtc aaaggatagg ctagagcctg ctgtaccagt ctatcaggcc ttgctgtcag
    27421 ctactaaatg aatgagtcag aaaaaggtgc tatgtaggtg cctttttctg cgttttgctt
    27481 taggctgata gtgagtttgc ttgaagtcaa gactggcttc atgcaggctt cagagtcttt
    27541 gctaggaatg ctataaggtg ggttctgagc ttatctattt aggatatgtg acaaatgctg
    27601 ttaaaatatg ttacactagc attagcttta atttcaatag aaagtatctg atataggtta
    27661 tgaattatca ttttgatgcc tctaagttaa agttgggcat gcgtacgttt aaaactggct
    27721 tagctgtgtt ttttgttttg cttttgtttc atttttttga ttttcagggc ctgcagatag
    27781 gggccttgac agctgttttt agcttgagag agagctttga taagacgatc tcctttggca
    27841 cctctcgtat tttaggaaat tcgattggtg gtttttttgc gattatattt tacctgcttg
    27901 atactctttt tcagggcgca ttttgggtta ccttggtttt tgttccgata ttgacgatgc
    27961 taaccattat gtttaatgtg gcttttaata atcaatctgg catcatcggt gcagttgctg
    28021 ctcttttaat tatcaccttg tctattccta ctggcgaagc ttttatgtat gttattgctc
    28081 gggtttttga aaccttttgt ggggttttta ttgccattct tgtcaataca gacgtggagc
    28141 tgattagaaa taagtggttg agcaggaagc tcaaaaaatg atgtcagaaa acataacatg
    28201 tgaccttgac agtttattaa aatcaaccta taataggggt gtgaaaggaa gttttcatga
    28261 aagaaaaaga actcagacgc tcaatggcag tctttccgat cggtgcagtt atgaccttga
    28321 cagatctatc tgctcggcaa attcgctatt atgaggacca ggagctgata aagcctgaga
    28381 gaacagaggg caaccgtcgc ttgttttcct taaacgatat ggatagactt cttgaaatca
    28441 aggacttttt ggacgaagga ttaaatattg cggcaattaa gcgagaatat gctgaacgcc
    28501 aggataaatt aatgcaaaag caaaaggtat tgactgatgc agatgtgaga cggatcttac
    28561 atgatgagct tcttaatcaa ggtggctttt ccaccccttc acagcatatt gggaattttc
    28621 gtatctagca tacgactggc atgaaagaaa aaggagattg attaatggca atcacagcag
    28681 ctgatgttcg tcgcgaggtc aaagaaaagc atgtgacctt tcttcggttg atgtttacgg
    28741 acattatggg tgttatgaaa aacgttgaga tacctgcaac tgaggagcaa ttagataaag
    28801 tcctatctaa taaggtcatg tttgatggct cctcgattga aggctttgtg cgtatcaatg
    28861 aatcagatat gtatctctat cctgatttag acacttggat cgtctttcct tggggagatg
    28921 aaaatggaac tgttggtggc ttgatttgtg atatttacac tgctgaaggc aagccctttg
    28981 ctggtgaccc acgtggcaac ctaaaaagag ccttgaagca tatggatgag gttggctatc
    29041 agtcctttaa ccttggtcca gagccagaat ttttcttgtt taagatagat gaagctggag
    29101 aaccaacgct tgaggtcaat gacaagggag gctattttga cctcgctccg attgatctgg
    29161 cagacaatac ccgtcgtgaa attgttaatg tcttgaccaa aatgggcttt gaggtcgaag
    29221 ccagccacca tgaggtagct gtcggtcagc atgaaattga ctttaaatat gcagatgcct
    29281 tgaaggcctg tgataatatt cagatcttta agcttgtggt caaaaccatt gcgcgtgagc
    29341 acgggctcta cgctaccttt atggcaaagc cgaaatttgg tattgccggc tcaggtatgc
    29401 attgtaacat gtccttattt gataaagggg gcaacaatgc cttttatgat gaaaatgata
    29461 agcgtggcat gaagctatca gatgatgcct attatttctt aggtgggttg atgaagcatg
    29521 cttacaatta caccgctatc acaaatccaa cggttaattc ctacaagcgc ttggttcctg
    29581 gttatgaggc tcctgtttat gttgcttggg caggaagcaa tcgttcacct cttattcgtg
    29641 ttcctgcttc tcgtggtatg gggactcgtt tagaattgcg ttcggttgat ccaacagcca
    29701 atccttattt agcacttgcc gttttactag aggcaggctt agatggtatc attaataaaa
    29761 ttgaagcgcc ggcaccgatt gaggctaata tttacatgat gacagcagag gagcgcaatg
    29821 ctgctggcat tgttgattta ccgtcaacac tccataatgc tctaaaggcg cttcaaaagg
    29881 atgaggtcat tcaaaaggct ttaggtgatc atatttacac caacttttta gaggcaaaac
    29941 ggattgaatg gtcttcctat gcgacctttg tttcgcaatg ggagattgat aattacttac
    30001 acaactatta gaaaatcaaa actcactcag ctttttgagt gagtttttta tgcttttatt
    30061 cagcagatat ggttatttat acttatcgtt ccttttatac gctatgagga cagaagtgtc
    30121 tggtttatct atttataaaa ataaaatcaa aaattttcag ataaatctat ttcctttttt
    30181 cagaattatg gtataatcta atttaattat tttaaataac tattttgtta ggaggaaggt
    30241 tatatgacag tactaggaac aaaagcatgt aagcgtctgg gcttagcggc agttacgcta
    30301 gcctctgttg ctgccttgat ggcttgtgga aataagcaat cagcgtcaac agacaaaaag
    30361 agtgagatta attggtatac gccaactgag atcatcacac ttgatatctc aaaaaataca
    30421 gatacctatt ctgctttggc tattggtaat tctggcagta accttttgcg tgctgatgct
    30481 aaggggaaat tacagcctga tttggctgaa aaggttgatg tgtcagagga cggcttgacc
    30541 tatacagcaa ccctgcgaga tggcttgaaa tggtctgatg gtagtgatct aacagcagag
    30601 gactttgtgt acagctggca gcgaatggtc gatcctaaga cagcctcaga gtacgcttac
    30661 ttggcaactg agtcacatct gaaaaacgca gaggacatta atagcgggaa aaatcctgat
    30721 ctagactctc taggggtaaa ggctgatggg aataaggtta tttttacctt aacggagcca
    30781 gcaccacaat ttaagagctt gctgtccttc tctaactttg ttcctcaaaa agaatccttt
    30841 gtcaaggacg ctggcaagga ctatgggaca acatcagaaa aacaaattta ttctggtcct
    30901 tatattgtca aggactggaa tggcactagc ggaaccttta agctagtaaa gaataaaaac
    30961 tattgggacg ccaaaaacgt caaaactgag acagttaatg ttcaaacggt taaaaagcca
    31021 gatacagctg ttcaaatgta caagcaaggt aagctagact ttgcaaatat ttctggtacc
    31081 tcagctattt acaatgctaa taaaaagcat aaggacgttg ttccggttct tgaggcaaca
    31141 acagcctata tcgtatataa ccagacagga gctattgaag gcttgaacag tcttaaaatt
    31201 cgtcaagcct tgaatttggc aacagaccgt aagggaattg tatctgcggc tgttgataca
    31261 ggctcaaagc cggctacagc gctggttcct acaggtcttg ctaaattatc tgacggaaca
    31321 gatctaacag agcatgtggc acctggctat aaatacgatg acaaggaagc tgcaaagctc
    31381 ttcaaggaag gcttggcaga gctgggcaag gatgccttga caatcaccat cacagctgat
    31441 gctgatgcgc cggctgccaa gtctgcagtg gattacatca aggaaacctg ggaaacagct
    31501 cttcctggct tgaccgttga agagaaattt gttcctttca agcaacgtct tgaggatact
    31561 aaaaaccaaa actttgaggt tgcagttgtt ctttggggtg gtgattatcc aaaagggtct
    31621 accttctatg gcttgtttaa atcagggtct gcttataact atggtaaatt tacgaatgca
    31681 gactatgatg cggcctacaa caaggctcta acaacagatg ccttgaatac agatgcggct
    31741 gctgatgatt ataaggcggc agaaaaagcc ctttatgaca atgcccttta caatcccctt
    31801 tacttccgta gcggtgaagg cctgcaaaat ccaagcatca aaggtcttat ccgtaattca
    31861 actggtctaa atgttgactt tacttacgct tataaggact agcaataata ttattgtaag
    31921 cctatactga cctagcaagg ccacagctcc ttgatgggaa gtgtttaaga gaagcttagg
    31981 gctagctagg agtgtctatc ctgtaggcct tggcaagcat attgcaagaa ttggtcttaa
    32041 ccagttcttg cttttggtta gaggaaaaat atgattaaat atcttttgaa gcgagtggct
    32101 attttagtag tgacactctg ggtggtgatt accctgtcct tctttttgat gcaggtgatg
    32161 cctggaacac cctataacag tcctaaatta actgatgaca tgattgctat gctgaatcag
    32221 cagtacggct tagataagcc tctttggcag caatatttga agtatttgtt tgatattctt
    32281 catggtgact ttggcaccag ctatcagtcg attaatcaat cagtgacaac cctgatctcg
    32341 cagcgtctgg gggtatctgt gcacttagga gtacaggcgc ttattgttgg tattagctct
    32401 ggcttagctg ttggtgctgt ctcagcgcgg aataaaaata atagcattga tgccatttta
    32461 agtgttatct caacgcttgg tatttccatg ccgtccttta tcattggctt gctgctgctg
    32521 gattatttgg gctttaaatg gaatttactt cccttgtctg gctggggaag ctttgggcaa
    32581 acgattttgc cgacgcttgc tttagctatt ccggtctttg ctcaggtgac ccgttttttc
    32641 cgcagcgaga tgatcgagac cttatcgaca gattatattc agctagctag ggcgaagggc
    32701 ttgactaagc gtcaggtgac tcgtcggcat gcttaccgca attcgatgat tcctgtgtta
    32761 accttggttg gtccgatggc tgctggtatt ttgacgggat cagccctgat tgagcagatt
    32821 ttttccattc cggggattgg gcagcagttt gtgacctcta ttcccaccaa ggattaccca
    32881 gtgattatgg gaacaacgat tgtctatgcg ctaatgctga tggttgctat tttggcaact
    32941 gatatgatca ttagtatcgc agatccacgt gttcgtttgg gataggagag tgctatgcta
    33001 gaagaaacaa aatcatttaa gcttgttgga gcaggtagct tagcgacaca agaaaaaatt
    33061 gaaaagccgg cgctttcctt tcttcaggac gcttggcgta ggctaaagca caataaacta
    33121 gctgttattg cgatggggtt tttagctgtg ctgcttttgt tttctattgg ttctttattt
    33181 gttgtatcta cagatgatgc caatagcttt aacagtaagg aggtaagcat ataccgtaac
    33241 ctgccgccaa agctaagcag cagcttgcca ttttggaatg ggaccattac ctacgctggt
    33301 aatacagagc ccaatgacgc ttatgcggat caaggggtcc cagaggacaa ggccttctta
    33361 ctcgggacgg ataatctggg gcgcagtatt ggaaaacgta ttacggtagg gattcgtatt
    33421 tctcttttga ttgctattgt cgcaaccctg atcgatctag tgattggggt aacctatggc
    33481 ttggtctcag gctttgttgg tggcaagact gacatggtga tgcagcggat cattgagatt
    33541 atctcctcta ttccaaacct tgttattgtg accatgcttg gtcttttgct tggcaatggt
    33601 gtgacttcaa ttattatttc aattgcgatt gtaggctgga cctcaatggc taggcaggtc
    33661 cgcaacctaa ccctgtctta tcgagagcgt gatttcgtcc ttgcttctcg tgccttggga
    33721 gaaagtaata tcaggattgc ctttaagcat gtattgccaa atatttcagg gattattatt
    33781 gttcaaatca tgatgactgt tccgagtgct atcatgtatg agtcagtttt atctgcgatt
    33841 aatttaggcg ttaagccacc gacagcttcg attggttcat tgattactga tgcacaagaa
    33901 agcctgcaat attatcctta tcaggtgctg ctgccggctt ttgccttggt gttaatttcg
    33961 ctagccttta ttttgttggg tgatggcttg cgtgacgctt ttgatccaaa atcaagtgat
    34021 gaataggggg aaataaaatg acgaatgaaa ccattttaag tgtcaaaaac ctccatgttg
    34081 attttaaaac ctacgctgga gatgttaagg cgattcgtga tatcagcttt gagctaaaaa
    34141 agggagagac tcttgcgatt gtgggagaat caggctcagg gaaatctgta accactcgca
    34201 cgctgatggg gttaaatgct aagaatgcaa gtatttcagg gaatatttgc tttaagggca
    34261 agcagctcaa tgagctgaag gaggaggaat gggtcaaggt gcgtggcaat gaaattgcaa
    34321 tgatcttcca ggatccgatg accagccttg atcctaccat gacaattggc atgcagattg
    34381 cagaggcaat aatgattcat caaagcattc ataagacaga agccttgaag cgtgctttag
    34441 acctgatgcg tcaggttggt atcccaaatg ctgaggagca ccttaaggat tacccacatc
    34501 agtggtctgg gggcatgcgg caacgggctg ttattgccat tgctctagct gccaatcctg
    34561 atattttgat tgcagatgag ccgacaacag ctcttgatgt taccattcag gcccagattt
    34621 tgaagctgat gaaggatatt cagtctcaga ccgcatcatc gattatcttt attacgcatg
    34681 accttggtgt tgttgctgga atggtagatc gcgttgctgt catgtatgct ggaaagattg
    34741 tcgaatatgg aacggttgac gaggtatttt atcatccgca gcacccttat acctggggct
    34801 tgctcaattc gatgccaaca acagctactg cagcaggtag cttgaggtct attcccggaa
    34861 cgccgccaga tttattaaac cctccaaagg gagatgcttt tgctgcccgt aatgagtttg
    34921 ccctagacat tgaccatatc aaagagcctc caatgttcaa ggtaagtgac agccactacg
    34981 cagcaacctg gttgctagat gagcgtgctc ctaaaataac ccctccattc ccaatccgca
    35041 agcgttgggc aaaatggcag gaaatggaag agaggaaggc ttaatgacag aagctcgtaa
    35101 aaaattaatc gaagtaaaga atgtttcctt aacctttaac aaggggaaga aaaacgaggt
    35161 taaggctatt gatcgcctta gctttgacat ttatgagggg gaagtatttg gccttgttgg
    35221 ggaatcaggc tcaggcaaga cgacagttgg tcgagctatt ttgaaactgt atgacattag
    35281 tgatggtgag attatcttta acggagaaaa tgtctcccaa ttaaaaggga aaaagctgca
    35341 tagctttcgt aagcatgcac aaatgatctt ccaagatcct caggctagtt tgaacggccg
    35401 tatgaaaatt agagacattg ttgcagaggg cttagacatt catggcttga cagcctcaaa
    35461 ggcagagcgt gaagcaagag tccaggagct gttaaagctt gttgggctca atcagaacca
    35521 tttgacgcgc tacccacatg aattttccgg tggtcaacgc cagcgaattg gcattgcgcg
    35581 tgccttggct gtgaagccga cctttattat cgcagatgag ccgatttcag cgcttgatgt
    35641 gtcgattcaa gcacaggtag tgagtctcat gcagcaattg caaaaaaagc gtggcttgac
    35701 ctatctcttt atcgctcacg atttgtctat ggtcaaatac atttcagacc gtattggtgt
    35761 gatgcattgg ggcaaaatgc ttgagattgg gacatctgat gaggtttaca atcacccgat
    35821 tcacccttat acgaaaagct tgatctcggc cattcctgag ccggatcctg aaaaggagcg
    35881 taagcgtatt gcagaggttt atgatcctag ccaggagcta gatggccaag agcgacaaat
    35941 gcatgaaatc actcctgggc attttgtctt agcgactcag gccgaagccg agcagtaccg
    36001 agcagagtgt ggcctttaag agactagcat aacagcaatt tcctaaaaag gctgatgtga
    36061 tagtttttta ggtatgacag accaaaagtc gtatgacctt tgccgatcaa aagcaggtgc
    36121 catgcgattt tggtggtatg gtggagcttt gtcagccaac ctagactgca caaaaagctc
    36181 cttatgatag aatttgtagc atgaggttgc gacacaagtc taccctaaaa taaaacaaaa
    36241 taaaacaacc gaacaggtct agctttctga gatttcaaaa gccagacctg ttcggttttt
    36301 aatgaatgag actaggtcat aaagtatctt agttaagatt gtctaaagtg cagctctttt
    36361 tgctgtgctt gctgctgttt ttataaaatg actcgtggga atcaatcagc ctgtagtcaa
    36421 atgttatcgc tctctttttg agatgtggct tgacaggttt gctaagctca gcaggctatt
    36481 tttagtagta tagctagaca aaggccctta agctagctca gcacgtcact ctgttaagct
    36541 tagctaacag cacgtgttgg gcaagtagta tgcctcatag ccttgtacgt cagtcattga
    36601 cgttgacgca acaaaaaaac acgagtctct aagctcgtgt caaagatcta ttggctatca
    36661 ggcgttagaa ccatcggaat gataataggc tcgcgctctg tcttttcgta aaggaaggga
    36721 cgaagcgcat taacgatagc accattgaca gactggatac tagcgtcctt atttttcaga
    36781 gcgatacgaa tcgcattgaa aagcacgcgc tgactctctc tgatgagctc gcctgactcg
    36841 cgcatgtaga taaagccgcg gctgagaata tctggtccgg ctaagatcat ctgtgtctca
    36901 aaatcaacag tcgccactgc aaggacaacc ccgtcctctg aaagatcacg acgatcgcga
    36961 aggactgctg tcccaatatc tccaatgcca ttgccatcta cataaatgtc ctgagcattg
    37021 aaatgaccgg ctatacgagc gctatcactg gtcaaggcca atacgtcacc attttccatg
    37081 ataaagatat tttcctctgg aatcccaata tcaacagcaa gcccagcatg aaccttctgc
    37141 atacggtatt caccatggac aggcataaag tattttggct taataaggct aagcattagc
    37201 ttttgctcct gctggccacc atgaccggag gtgtggatat tgttgacctt tccatgaata
    37261 acgtcaactc cagcctcctg aatcgtattg attagcttat tgacgctgac ggtattacca
    37321 ggaattggac ttgatgaaaa gatgacagtg tctccaggct gtaagctgac ctgtctgtgg
    37381 gtaccattgg caatcctagc aagggcggcc atagactccc cttgactgcc ggtacacatg
    37441 atcaaaatct cactagcgtg gtaatgttta atctcattag gctcaataaa ggttcccttt
    37501 gggaccttga tgtagccaag ctcaataccg ttaacaatag ccttttccat tgaacgacca
    37561 aatacagcaa tcttacgccc tgtcttaaca gcggcttctg cagcctgctg caagcggtag
    37621 atatttgaag caaaggaagc aaaaatgata cgtccatgaa tgccttcaat aatgttcatg
    37681 attgactggc caacgacctt ttcagaattc gtaaaggttg gtatctcggc atttgtcgaa
    37741 tcggacaata gacaaagaac cccgtcctta ccaagagcag ccatgcgatg tagatcagcc
    37801 ggatcaccaa caggtgtaaa gtcaaacttg aagtcgccag tacagatgac tttcccttgt
    37861 ggggtgtgga taacaatccc aagtggctct ggaatagagt gagttgtttt aaagaaggta
    37921 acgctcatat gcttaaaggt gagctcggta ttgtgattaa tctcatagag cacagcatcg
    37981 cgtaagagac cgtgctcctc cagctttcct cggataagag ctagagctaa ggggcctgca
    38041 tatataggca cattagcttg ctttagtaaa aaaggaatac cgccaatatg atcctcatga
    38101 ccatgagtaa tcacaagagc cttgacgcgc tccaaattgt caacaatata agagtaatcg
    38161 gggataacat agtcaatccc tagcagatcg tcctctggga atttgatacc ggcatcgaca
    38221 atgatgattt catcttgata ctcaataccg taggtgtttt tgccgatctc tcccagacca
    38281 ccaatcgcat aaaccccaac ctcattaggc cttaaactga tatttgtcat gttaaaactc
    38341 cgttaatgtg aaaacaccag tttctttttc gtagtctagg tgcttgtctg agagcagctc
    38401 gatgaattcg acattgtaat cggtgtgctc ttcaaccatc ttgcgggctt tgatacgccc
    38461 ctcaagctca cttgcagcgt ctatatctag gtatagggcc tgtgtgtttt cacgacgcgg
    38521 actgcgttcc tttgtttctt ggtagaaaac tttataaatc attgatgata tcttcctttc
    38581 atgatgaatc gattatccaa acaataacaa ataggtcaaa acgagaaggc ctctgttttg
    38641 acgattacct atcatgtgat tattgtgtaa tagatttaaa cctgattctg tgcaattact
    38701 aagattatac catactatcg gcttttagta aaaagtttcg ataaaattat tctcttgacc
    38761 ggtgatgagg ctgtggctgt ctccttttcc atgaccttta ttttatgtta taattgtgga
    38821 atagaaatga cttgagaagg gcttagtatg aagacacttg catttgacac atcaaataag
    38881 gcattatctg ttgctctatt agacgatggc acattattgg ctgatcttac gattaatgtt
    38941 aagaagaatc acagtattag tctgatgccg gctattgatt ttttaatgtc ctcagctgac
    39001 ctgaagccaa aggatcttga tcggatcgta gtagcagaag ggccgggctc ctatactggc
    39061 ttgcgtgttg ctactgctac agcaaaaatg cttgcttata gcctaagtat tgacctcgtt
    39121 ggcgtatcaa gcctatatgc cctagcggct tctacttgcc gagaaaaccc tgatagcttg
    39181 gttgtccctt tgattgatgc tagacgacgc catgtttatg tgggctatta tcaccatcaa
    39241 aaagctgtga aacaggataa gtacgcgtcc tttgatgctg ttttagcaga actggtctct
    39301 tgtgaccatg tgatttttgt tggagaagtg gagggctttg cagaggacat tcgatcagcc
    39361 ttgccagagg ccaagataaa gccaagtctg ccatcggctt ttgaggttgg tttgctaggc
    39421 agcagccttt cagctgacaa tgtagcagcc tttgtcccac aatatttgaa gcgggtcgag
    39481 gcagaggaaa actggctcaa aactcatgct gccggtgatg acagccagta tgtcaagcga
    39541 gtttagcgat gatgtctatc caagaaaaag cagcagctgt ctatcaggtg ctaaaagagg
    39601 tctatggtca atccccttgg accttaaagc agatagtgtc tgatatgcag caggagcatg
    39661 ttgattattt taccttttat catcaggaga ccctgctagg ttttttagcg attcaacagc
    39721 tgccaggaga aatggaaatc actaatctag ctgttttgcc aagctatcag gggcaaggga
    39781 ttgcctcttg gctcatggga cagctagatg gctttgaggg agtgatattt cttgaggtta
    39841 gagcgtcaaa ccatagggcg cagcagcttt accttaagca tggctttgag gtggtaggcc
    39901 agcgtagcaa ttattatcat gatccaatag aagcagcctt gatcatgagg cgggaaggaa
    39961 agaatgacag atagatatat tttagcagtg gagagctctt gtgatgagac aagtgttgct
    40021 atcttaaaaa acgacaacgt cttattgacc aatattattg ctagtcaggt tgaaagtcac
    40081 aagcgttttg gtggagtggt tcctgaagtg gctagtcgtc atcatgtgga ggtgattacg
    40141 acttgctttg atgacgcact caaggaggcc cagcttgagg cttctgactt gactgcggtt
    40201 gcggttacct atggaccagg tctggtgggg gccttgctag ttggcctagc agcagccaag
    40261 gcctttgctt gggctaatga tttgcccttg attccagtca atcatatggc agggcacctg
    40321 atggcggcac gcgagcaagg agagctggaa taccctctta tggctctctt ggtttctggt
    40381 gggcatacag agcttgtcta tgtgaccgag ccaggagaat atcatattgt tggagaaaca
    40441 cgtgatgacg cagttggtga ggcctatgat aaggtaggac gtgtgatggg cttgccctat
    40501 cctgctggtc gtgagattga tcagctagct caccaaggga cagataccta tcattttcct
    40561 cgtgccatga tgaaagagga tcatttagaa ttttcttttt caggcctaaa atcagccttt
    40621 atcaacctgc accataatgc gcagcaaaag ggtgaggagc ttgtgcttga ggatctctgt
    40681 gcttcctttc aggctgcggt gttagatata ttgttagcaa aaacgaagaa ggcactcaag
    40741 cagtatccat caaaaatgct agtcgttgca ggtggagtgg cagctaatca gggacttcgt
    40801 gagcgtttag ctgaggaaat aactgatata gctgttgtga taccacctct aagattgtgt
    40861 ggagataatg ctggtatgat tgcgttggcg gcggtggttg agtacgagaa agggcatgtg
    40921 gcaggcttgg atctaaatgc taagccgagt ctagcctttg atagctttca tcagcagtag
    40981 tattagtatg aggagattgt catgttttat ttattgcttc ccccattgat ttgcagtgtg
    41041 gtatttttgg ctgtctatat taaggagcca agaacgctgt ggctaggagc tagctttgtg
    41101 acgaccctag gtgttagtct cttgtgtgct atgatttaca ttttttcaat cgaagaaaag
    41161 cttcagggag ttggtatcct agtgctaggt gttattgggt ttcttgcgat tgtatggttg
    41221 atgtctagtc cctttatcct cttgctcttt ctaagcttta atggcattag gctcatcaaa
    41281 agagaggggc tttcctttcg gaatttattg ctgattggct cagcggtgct attgtttgta
    41341 catcctttta tcagcagact attgttagag agtatcggtg attcaaagct tttaaggatc
    41401 atgtatgaaa cgagtgacct cttaatcctt tacctcttgt taatcgtatc agtctacacc
    41461 atctcaagca tgctgaatac cttttacttc agaaaaacca aggaggatta tattattgtg
    41521 ctgggcagcg gcttaaatgg agaccaggtc acccccttgc tagctagccg cattaataag
    41581 ggcattcaga tttaccagaa aaatcctggc agcaagctga tcatgtctgg tggcaaaggg
    41641 gctgatgagc taatagctga gggtgaggcg atgtgtcgct atgcaatcca gcaaggaatc
    41701 aaaagtgaag atatattagt tgaaaaccaa tccagaaaca ccagagaaaa tattctgttg
    41761 tctaagcaat taataccatc tggagcttcc ttttgcttgg tgaccaatcg ttaccacctg
    41821 tttagagcct tattactggc taaggagcta gccttgcctt gcaggtgcta tggggcaaaa
    41881 acaaagctct actttagtat gaatgccttt atcagagaga ttgttggcta tctccaatta
    41941 aagaaaaagc agcacctgct ggcaatgctc atcttaacag taggctatat agccataaga
    42001 gtggtgatga tctatatgct gcacatttga tgtcattggc aaaaaagcta aggctagtca
    42061 cctcgtcttg ggctgaaaaa gtctctctta ggtccttttc tcagatgata tgagcaagca
    42121 gcctttttaa aaaggctaca tctaggattt tatggagcct tagagcttgt tgtgtggtga
    42181 tgttcaatgg aaccaatcac aattgttaca gcaaaaagca ggcctttagg aacgtttgct
    42241 ttgctggtaa gtccttttac ttgcagaggc tggctacacc agccaaaggc taaggcaagt
    42301 gatttagctt gtgatgatca aggagtttta agacgtaaaa aaatagctcg gtatcttggc
    42361 ataccgagct atcatgataa attggcttct atgattacta aatcttaaac aaggtgagtc
    42421 aagcttacca gctagcctta gtgattcctg gtagttggcc tttgtgagct agctcacgaa
    42481 aattgatacg gctgacacca aacttacgca tgtaagcatg gggacggcca tcaattctat
    42541 cacgattttt caagcgattt ggatttgaat cacgtggcaa tttgcgcagt gcttcataat
    42601 caccctttgc tttaagctcg cgacgaaggt cagcatactg ttcaatcagt tggagctgct
    42661 tatggtattt agcaattttt gacttctttg ccattgcttt ctccttctta atatttaata
    42721 atctcagagc gttatcagca ccctgaattt cctcaaccag tcattaatca gttaagaaaa
    42781 catagctcta ttatacacta atttcaatca aatgcaagaa aaatagataa ctgattaacc
    42841 agttgaggca aaaacagcct gccagtgagt ctactgacaa gcctagctta gctttgcgag
    42901 cttcctgcca cccagccaga gcagagggca gctgtaatgt taaagccacc tgtatgagca
    42961 ttaacatcta agacctcacc agcaaagtaa agtcccgcga cctttttgct ttctagggtc
    43021 ttagggttga tttcttttaa gtcaatgcca cccttggtta caaaggattt ggccagagat
    43081 atttttcctg tgattggaat cggtaattgc ttaatcctgt tgacgagctc ctgagtctgt
    43141 gtgggagtta actgctttcc tttttctgga tagccctttg ctaaaaaatc agcgactcgc
    43201 tcaggcatca aagtcttgag cgcattttta agggcctttt cccggtgctg cgctagatag
    43261 ctgagcagct cagctgcgga ggtttgtggc agcaggtcaa gctctgcgat gtcacctccc
    43321 ttaacaaagg aggaaagcct gagagcagcg gggcctgaca acccaaaatg ggtaaaaagc
    43381 aaatcgtgag tgatctgatg tttcccacag ctaagggtca catcagcaag tgaaatcccc
    43441 tgcagagcct tatgtggaaa gtctgttaat aaggggcttt ccgcagcctc tagctcggtg
    43501 acagctatgt taaagtggcg agcaatatca tagccaaagc ctgtcgatcc agtagatggg
    43561 taggacttgc ctcctgttgc cacgataagc ctctcgcagc tgaaggtttg atcaactgat
    43621 ttgaggtaaa aaaggttatt ccgctttttg accgagacaa tctcggtact gatcagcacc
    43681 tgagctccta gtgacttgat tttttgctcc agcgcattga taatcgtctt tgattgatcg
    43741 gtcgtaggaa acatgcgtcc atgatcctct tccttgaggg tcaccccatt ttccttgaaa
    43801 aaggcaatga tgtcatgatt atcaaattgg gaaaagacgc tatagagaaa gcgcccgtta
    43861 ccgggaatgc ccgcgattag ctcatcatgg cttccgctat tggtgacatt gcagcgtcct
    43921 cctccagtcc ctgctagctt tttgcctagg cgcttgtttt tgtcaagtag gagtgtcttg
    43981 tagccatagt agctactaga gatggctgcc atcataccag caggaccacc tccaataata
    44041 atcgtgtcgt atagtatcat gtgcttattt tagcataaca tcaagcgatt taacagtaat
    44101 gtaaactagg ctaaattgac agaattctgg tattgtgtta ctatttttaa taagaatatt
    44161 cagttacagt aataaagagg aaattatggc aatagaaaag acagttagtg aactagctga
    44221 cattttggga gtgagccgcc aggctgtcaa taatcgtgtc aagtccttac cagaggagga
    44281 ccttgataaa aatgataaag gggtcactgt cgttaagcgt agtggcttgg ttaagctgga
    44341 ggaaatctac aagaaaacca tttttgatga tgagccaatt agtgaagaga ccaagcagcg
    44401 tgagctctta gagattctgg ttgacgaaaa aaacactgaa atcactcgct tatatgagca
    44461 gctaaaggca aaggatagcc agctggctgc taaggacgag cagatgcgta ttaaggacgt
    44521 tcagattgcc gagaaggaca agcagctgga tcagcagcag cagctgacag ctaaggctat
    44581 ggcagacaaa gagaccttga agctggagct tgaggaagca aaggctgagg ctgatcaggt
    44641 acgactgcaa gcagaggaga tacagtctga aatgggacct aaaaaaggtt ttttaaatcg
    44701 tttatttggt aaataacagt ataccaagac cctctaaggg tcttttttga ggagagaaga
    44761 atgaaacaat tagaagcata tattgccttt gatatggaat ttaatactgt caatgaggtt
    44821 agtcatatca ttcagctttc agcggtcaaa tggcacaagc atcaggaggt tgacagcttt
    44881 gacagctatg tttacactgc tgttcccctg caaagcttta tcaatggcct gacaggcatt
    44941 acctcagata agatcgtatc agcacccaag gttgatgagg tgcttgatgc ctttaagcaa
    45001 tttgtcggtg acacgccttt gataggctat aatgcacaaa agtctgattt gcctatttta
    45061 gcagcaaatg gcttggatct gtcagcgcaa tatgcagtcg atgtctttga tgaagcctat
    45121 gagagacgaa gcagcgacct aaacgggatt gctaatcttc gcctgcaaac agttgctgat
    45181 tttttaggga taaaaggaag aggacataat agcttagagg acgctcgtat gacagcgcgt
    45241 gtctatgaag cgtttgtgga atttgacgac aataagtctt acctaaacaa acaaaaagaa
    45301 gcgattgcag ataacccctt tgcagctctg ggagggcttt ttgactagca gcgctagtca
    45361 tttctctgaa aaagaaaaat gacctaaggt cagggcttgc ttgtgacctt gggtcatatt
    45421 ctataatgag gacagaaagg aggtgaagga catgtctgat atttactcaa ctggtgagct
    45481 agcaaaagca gcaggtgtca ctgtcaggac agtgcaatat tacgataagc gtgggatttt
    45541 gttgccttcc cagcttactg aaggtggacg gcggatttac accgagtcag atttggagcg
    45601 attgaaaatc atttgcttct tacgggacct agatttttcc attgagcaga ttaagcgcgt
    45661 gctagcagaa gacaatgtta tggcggtgct tgacctcttg ctggtggatc atatccaaca
    45721 gctggaacaa gacttaagga cgaaaaagca tcagcttgac acagctgtca agcttttgtc
    45781 aggtattcgc tgctcatcta gtcactctat caaaaaccta tcagacatgt cacttaccat
    45841 gaacaatcaa aaagcttggc gtcgtttgca gttgaaaatg tttagtaata ttgccctagc
    45901 aatattggtt catgtgatgt tagtgttact aactagctat tttcatctat cttggttggt
    45961 atggatagag gctccactat ggataatctt ttttacttta ttgatcgttt attttcgtaa
    46021 acaatttgag tacctatgtc caaattgtca tactattttt gaaccagact ttaaagagtt
    46081 tgccttggca ggtcacacac caaggacccg caggctgacc tgtcctcatt gccatcaaaa
    46141 atcttactgc cttgaattgg ccaaggaaaa ataatggaaa atctccgctg gatacccagt
    46201 ggagatttct tgctattaga atggtagctt gccagcaaag gctcctagag ttttcttagt
    46261 cgcctcatca atttgagcga gggctgcatt gatggcctga gcagtcatat cctgaagtgt
    46321 ctctatatcc tctgggtcaa cgactgcttc cttgaaatca atgctaacca attgcttatc
    46381 acctgtaaag gttgcagtga ccagctcctg agctgacttt cctgtaaatt gcatagctgc
    46441 taggtcagcc tgcttttgtt ccatttgctt ttgaagcttt tgcgcttgct tcatcatgtt
    46501 ttgcatgttc atcataagtt ccaattctcc taagttttga tacttaacta ttataacata
    46561 tcagacaaga cttcaaacat gtgatctttt aaagttaatg aaaaggccct gctagcctgc
    46621 aatgctttga tgtgctagcg actaacgaac aggtcgtttc ctttaaatag agttttcttg
    46681 ttgagcttta tagctggtgc ttgtttttgt gatgagcttg tgtgaggctg tcgttagtgt
    46741 tgttttaggt ggtttgacat caggagcgat taaaaaagtt atcagtttac atttttataa
    46801 taataactta agaattaatt taactttaga ttaatcttac tttatatttg attgctatac
    46861 ttagtccata acataaataa ccaaaaagaa agaggtaatc gttatgacaa caatgactac
    46921 aacaaaacaa tcaaagacaa ctctagcagc tcgttatttg aagcttggtc ttacttcagc
    46981 aatgtttgct ggaggagcct ttctagctct aggctcagca ccggctgtct ctgcttctac
    47041 ccatgctggt aatgatcagc cagcgactca acgcttaact gatcaggaga tctacgaacg
    47101 tgctcaaaag ctagacttgc cagactatgt gagaggctca atctacggta ttctcaacca
    47161 aaactcaagt gttacttatc caaaggatat agcaggtcta gagcagtcag aagctccaca
    47221 accccctgca gctccacagc tcactgacca agatgctcaa aagctggact tgccagacta
    47281 tgtgagaggc tcaatctacg gtattctcaa ccaaaattca agtgttactt atccaaagga
    47341 tatagccggt ttagagcagt cagaggctcc acaaccccct gcagctccac agctcactga
    47401 ccaagatgct caacagctag acttgccaga ctatgtgaga ggctcaatct acggtattct
    47461 caatcaaaac tcaagcatta cttatccgcg cgattattaa gcatctaaga tgattaaggt
    47521 gcacaatcga cgattaaaat gattgatgag ttaatgagat tagaattatt tggctaagtt
    47581 aagaattagt gttatacttg agagagtgta gcactaattt tttaatcaag gaggaagcat
    47641 gacctacaag atattattgg tggatgatga attggaaatt attgatatta acgaacgtta
    47701 tttgcaacag gcagggtatc gtgttaccac tgcaagcgat ggtagtcaag ccttggagct
    47761 ttttcataag gatcagtacg atttgattat cagtgatgtt atgatgccca atatggatgg
    47821 ctatgatttt attggggagg ttttactgga aaagccagat cagccctttc tctttatcac
    47881 tgcaaaaaca tctgagcctg acaagattta ttccttgagc ttgggagcag atgattttat
    47941 ttccaagccc tttagtccac gtgaattagt cttacgggtc aaaaatattt tgaatcggat
    48001 ttatggtaag gctaaccaag ctgactcctt agttattggg gatttggtca tggatcacag
    48061 cactcgaagg gttacagtgg caaatcaaga tctgaatctg accaacaagg cttttgattt
    48121 gttgtggatt ttggccaatc atttgaatca tgtcttttca aaaacagagc tttatgagcg
    48181 t
//
LOCUS       DARYMD010000011        47082 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYMD010000011 DARYMD010000000
VERSION     DARYMD010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47082
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            489..704
                     /locus_tag="TU818_000554"
     CDS             489..704
                     /locus_tag="TU818_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0923402.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKIAKVFNEPIEQVFSLVEGER"
     gene            701..1477
                     /locus_tag="TU818_000555"
     CDS             701..1477
                     /locus_tag="TU818_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL0923403.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGIGLVLGGLVGFGLARFNILE
                     NGFPISEEDTITGIKWGMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVPIANNASYLGLTFPIYEALMLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVMGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(1546..2802)
                     /locus_tag="TU818_000556"
     CDS             complement(1546..2802)
                     /locus_tag="TU818_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL0923404.1"
                     /translation="MITRLITFLTWTGQLVVAGVIAGVVAYVLTQAIHFIQAISFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWT
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINASAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIMEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLILPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLQNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(2888..3847)
                     /gene="nrdF"
                     /locus_tag="TU818_000557"
     CDS             complement(2888..3847)
                     /gene="nrdF"
                     /locus_tag="TU818_000557"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL0923405.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            complement(3992..6151)
                     /gene="nrdE"
                     /locus_tag="TU818_000558"
     CDS             complement(3992..6151)
                     /gene="nrdE"
                     /locus_tag="TU818_000558"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL0923406.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFTENVI
                     PNTMSFSSINEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIQAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNADMYLFSPYSVEREYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIRAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGAYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQAIM
                     TDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(6172..6390)
                     /gene="nrdH"
                     /locus_tag="TU818_000559"
     CDS             complement(6172..6390)
                     /gene="nrdH"
                     /locus_tag="TU818_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL0923407.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETEQIVFSGFQPAKLKDII"
     gene            6812..7075
                     /locus_tag="TU818_000560"
     CDS             6812..7075
                     /locus_tag="TU818_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL0923408.1"
                     /translation="MASKDFHIVAETGIHARPATLLIQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            7080..8813
                     /gene="ptsP"
                     /locus_tag="TU818_000561"
     CDS             7080..8813
                     /gene="ptsP"
                     /locus_tag="TU818_000561"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL0923409.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKYFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKVVFEEEKASLLSEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            9015..10442
                     /locus_tag="TU818_000562"
     CDS             9015..10442
                     /locus_tag="TU818_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL0923410.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERTAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVVLKPPTQGSISGLLLAEVFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDRVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTTNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            11095..12309
                     /locus_tag="TU818_000563"
     CDS             11095..12309
                     /locus_tag="TU818_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL0923411.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSTTLFQPSEFMKISYILAMSWLTVWFKRKQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            12405..12974
                     /locus_tag="TU818_000564"
     CDS             12405..12974
                     /locus_tag="TU818_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL0923412.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKKSTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKEKYLISKGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            12975..14927
                     /gene="gyrB"
                     /locus_tag="TU818_000565"
     CDS             12975..14927
                     /gene="gyrB"
                     /locus_tag="TU818_000565"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL0923413.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            15076..16800
                     /gene="ezrA"
                     /locus_tag="TU818_000566"
     CDS             15076..16800
                     /gene="ezrA"
                     /locus_tag="TU818_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL0923414.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     KTRERIRF"
     gene            17171..17452
                     /locus_tag="TU818_000567"
     CDS             17171..17452
                     /locus_tag="TU818_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923415.1"
                     /translation="MKITKALCVAGAVAVLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(17637..18092)
                     /locus_tag="TU818_000568"
     CDS             complement(17637..18092)
                     /locus_tag="TU818_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL0923416.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            18323..19630
                     /gene="eno"
                     /locus_tag="TU818_000569"
     CDS             18323..19630
                     /gene="eno"
                     /locus_tag="TU818_000569"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL0923417.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(19766..20002)
                     /locus_tag="TU818_000570"
                     /pseudo
     CDS             complement(19766..20002)
                     /locus_tag="TU818_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20211..20432
                     /locus_tag="TU818_000571"
     CDS             20211..20432
                     /locus_tag="TU818_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL0923418.1"
                     /translation="MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYAEYKADPETISHADFKKELGL"
     gene            20434..20694
                     /locus_tag="TU818_000572"
     CDS             20434..20694
                     /locus_tag="TU818_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL0923419.1"
                     /translation="MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKMVVLALEFGHRKDIY"
     gene            21347..21952
                     /locus_tag="TU818_000573"
     CDS             21347..21952
                     /locus_tag="TU818_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL0923420.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLAPKGCQRPKWSHQLERLFADTKPCLQVLSETYQLGIIANQAKGLK
                     ERLERFGISHYFALMISSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKALGMRAVRIHQGLAASSPDDRLYPSDVHISKLSDLLECF"
     gene            22420..25200
                     /locus_tag="TU818_000574"
     CDS             22420..25200
                     /locus_tag="TU818_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL0923421.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPVAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGHGFYIQDSQGSGLYIYPGSALGYVTGDVVQLTGTLTT
                     YKGELQLKTITKHHKINGELPTPIAEVTIPELEKASPSTLVKLSNVTVGDISSDKHET
                     SSFKVSDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFSL
                     EQFEVVKKVVREEEVTPLGRVVKIGQIQGASHTSPLLNQAVTVKEVVVTYPDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRVLTNSGGILLPETGYNTDLIPVLFKKGKQTIKAGD
                     SYQGRLAGPVSYSYGNYKVFVDDSSRMPVLVDGQLKPEKTHIKKDLSKLSIASYNIEN
                     FSANPSSTKDEKVRRIAESFIYDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLID
                     AIKALGGPAYQYVDIAPENNADGGQPGSNIRTGFLYQPGRVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWNSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHELSDRYSYFYRGNNQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSDQPKKTPAPAATTQASKAGRAQLLPKTGDKTALMVSILGLTAVFS
                     SFSLFRKCQERK"
     gene            complement(25622..25759)
                     /locus_tag="TU818_000575"
     CDS             complement(25622..25759)
                     /locus_tag="TU818_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0923422.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     regulatory      26003..26121
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            26119..26625
                     /locus_tag="TU818_000576"
     CDS             26119..26625
                     /locus_tag="TU818_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL0923423.1"
                     /translation="MTSFTVRDYVYIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            26722..28680
                     /gene="ligA"
                     /locus_tag="TU818_000577"
     CDS             26722..28680
                     /gene="ligA"
                     /locus_tag="TU818_000577"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL0923424.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGA
                     KASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAG
                     VNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIEDEDWLLNL"
     gene            28693..29715
                     /locus_tag="TU818_000578"
     CDS             28693..29715
                     /locus_tag="TU818_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL0923425.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINISAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGIFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPITLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            29724..32024
                     /gene="pulA"
                     /locus_tag="TU818_000579"
     CDS             29724..32024
                     /gene="pulA"
                     /locus_tag="TU818_000579"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL0923426.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWQHQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHDGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     LYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLRPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPVFDHHQ
                     FFDENGDYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMLDSILYW
                     TNEFNIDGFRFDLMGLHDIDTMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKG
                     NASQMPGIGFINDDQRNAVKGAEVYGSLEKGFVSGAPTEGLVAKSILGSDELVSYCTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGIYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETVAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHAGENTGFISFTVEDERKYRLIFSSFRNRLQSSANHVII
                     ETNDKRFQDSESMLDELTAMILDITQ"
     gene            32171..34050
                     /gene="glgB"
                     /locus_tag="TU818_000580"
                     /pseudo
     CDS             32171..34050
                     /gene="glgB"
                     /locus_tag="TU818_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
     gene            34117..35256
                     /locus_tag="TU818_000581"
     CDS             34117..35256
                     /locus_tag="TU818_000581"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL0923427.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVIIDGSKDVQVVGYNEVVGVPNED"
     gene            35246..36379
                     /gene="glgD"
                     /locus_tag="TU818_000582"
     CDS             35246..36379
                     /gene="glgD"
                     /locus_tag="TU818_000582"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL0923428.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYQQILTYLKRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVDRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRITSQARVTNSILLPKAVIGE
                     GAVIDYAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            36376..37806
                     /gene="glgA"
                     /locus_tag="TU818_000583"
     CDS             36376..37806
                     /gene="glgA"
                     /locus_tag="TU818_000583"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL0923429.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDPGMLGDLFDVGIERYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAA
                     TKQALQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            37825..40221
                     /locus_tag="TU818_000584"
     CDS             37825..40221
                     /locus_tag="TU818_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL0923430.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTEQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGIQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQIIENTRIVKDNQIYMANLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIMKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDTSLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFVNGTIPNSQHEGMEIYDALITHNDEY
                     FLLEDFSSYVKAQAKIDRLYRQKDRWSKMSLINIAHSDKFTSDDTITQYAKDIWQLKR
                     "
     gene            40563..40760
                     /locus_tag="TU818_000585"
     CDS             40563..40760
                     /locus_tag="TU818_000585"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL0923431.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            40794..41510
                     /gene="atpB"
                     /locus_tag="TU818_000586"
     CDS             40794..41510
                     /gene="atpB"
                     /locus_tag="TU818_000586"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL0923432.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            41528..42022
                     /gene="atpF"
                     /locus_tag="TU818_000587"
     CDS             41528..42022
                     /gene="atpF"
                     /locus_tag="TU818_000587"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL0923433.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAVLQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            42022..42558
                     /locus_tag="TU818_000588"
     CDS             42022..42558
                     /locus_tag="TU818_000588"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL0923434.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            42574..44079
                     /locus_tag="TU818_000589"
     CDS             42574..44079
                     /locus_tag="TU818_000589"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL0923435.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFESLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFETIRTTKDLPQEAELDVAIQAFKAQSNFK"
     gene            44097..44972
                     /locus_tag="TU818_000590"
     CDS             44097..44972
                     /locus_tag="TU818_000590"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL0923436.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVG
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            45140..46546
                     /gene="atpD"
                     /locus_tag="TU818_000591"
     CDS             45140..46546
                     /gene="atpD"
                     /locus_tag="TU818_000591"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL0923437.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            46559..46975
                     /locus_tag="TU818_000592"
     CDS             46559..46975
                     /locus_tag="TU818_000592"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL0923438.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVSEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK"
BASE COUNT        13379 a         8968 c        11052 g        13683 t
ORIGIN      
        1 cacataaaca aattgagacg aacagtagat tgtagctata tcacaggtga gatagtaatg
       61 atcgtgcgaa acaataaact gatttttcca tgcgggatat ttgttatcag tgagttgaat
      121 ggaactagca gctattgttt tattgttagt catctagtgt ttttaaggtg cttattttct
      181 gttacaacag tgatgacaac aggttaagct aagttcgatg gagcttggtt ttttattgtt
      241 acaagaaagc tcatagatgg tgattgcatt cttttatcat atgacaatgt ttctattttt
      301 gacaaatatt attgtcaaaa agtaaatgat ctgttacact ggagttggac tcatgaaaga
      361 aaaaagtaat cagtaggata acaataacaa agctatttta agcttatacc attgtgtcaa
      421 tggattgttg ccggaaatga ctggtgcttt ctgttcaatc aggagacagc atttattagg
      481 agtgaagcat ggcttatagg ttgagaaatc ggctcaagga gctacgagct agagatggca
      541 ttaatcagac gcagatggca gcattagcag gtgtttccag gcagaccatt agcctcattg
      601 agcgaaatga atacacacca tctattatta ttgcaatgaa aattgctaaa gtatttaatg
      661 aaccaattga acaagtattt agcttagtgg agggcgagag atgaaagctt ttatgacgga
      721 aaaggacagt acgttggtga gaatacttaa gtcattactg cttggatcag ggattggctt
      781 agtgttaggt ggccttgttg gttttggttt agctaggttt aacatattag aaaatggctt
      841 tccgatatca gaagaagaca ccataactgg aataaagtgg ggaatgagac cccttgttat
      901 cgtgcttatg ctgctgagca tttatgatat ttatcaagtt gtcaaagaat atgctagata
      961 tgtcaagcta agcgatgatg aaacagagga gctgtaccgt tacattaatc ttaagcatgc
     1021 ctatgcttta ggatttagcg ctatggctat ggtcttgaat atagtcgttt tttctttggg
     1081 atatagggtg cctattgcta ataatgctag ctatcttggt ttgacttttc ctatttacga
     1141 ggctctgatg cttgtggtta ttagtgttct ccatgcttat attttgaagg tttatactcg
     1201 gattcgcggg gtcaagatga cgcttgctcc taccttaaag gaattaaagc agaatatctt
     1261 acaacaggac gaggcagaat tgcaggctaa ttatcaaatg tcttttgagg ttgtcatggg
     1321 ccttagtggc tttatattac caggcattta cgtaatatta ttgcttttat ctatgatttt
     1381 tcaaagggtt gagctgaccg gactaatcat tactgctagt attcacctct atattctggt
     1441 gaaatccttt aaatcagcac atgattttta taggtaaggc gtaaggtttt acctactcaa
     1501 gaattgttat acagcaaaaa agctttgata agccattact ggcgatcaaa gctttttgtg
     1561 tttgttgaaa aagaggcttt tttgaaagag ctgttggctg agatagcttg tcaaacctac
     1621 aattgcaagc ggcacaaggc taatgagagg ttgtccggta atttcaatga gaaaaagagg
     1681 agcagtaaga ggtatctgat taatgattcc caaaaagagg gtcgctccaa tgacaatggc
     1741 caagggaagt ggtacagaga gataacctag ctgattgcta aggcttgcca gtagcaagcc
     1801 actagctcct ccaagcatca tagaaggagc aattttgcct cctttagctc cagaggcaaa
     1861 tactgcatag acagcagctg ctttacttag taagagcgag gcggtataag ataggctgac
     1921 atcatggtgt agcagcagga ggagaccggc cttgccattg cctaaaatct ctgggaaata
     1981 aaggcttaaa caagcactaa agccaaaagc ccctaagaca cgagggataa accatcggct
     2041 cttaggcttt gcctttggtg cgttttggag cagctgctgg tagcaaaagg ccagaaatgc
     2101 taagatggga ctggcaatga tagcccaaag gactgttgtc agttgccagg cttgtgggag
     2161 aatgagatac tgtatgtcct gatgtccgct tagaacaagc acactttgaa cagcagtaaa
     2221 ggcagttata gctgccgcgt aaatgtgttt aactgagcat tttttgacaa tagcctccat
     2281 gataaagaca atcgtagcta atggtgcctg gtaaacagct ccaagggcag ctcctgaagc
     2341 acaggctaaa agcaatcctt gctctgctgc tgatgcgttt atagctttat tgcaagcggc
     2401 agtcagtgcc acagcaacct cacgtgaagc accttcacga ccgacaggtg ctcccatgga
     2461 gacggttatt aattgcagcc agccatgaca aaattgtgtc caagggctga aatccttttg
     2521 ctgactgagt gtttgttgga taggctgaat aggcttggct tttttagcaa gtagctgcca
     2581 gccgagacca gcaatagctc cagccaacaa tagagataaa aaacgccttt ctggagctac
     2641 cgttgcaatc atggtgctaa aagacccaga ttggtatcca aagctaatag cctgtatgaa
     2701 atgaatggct tgagtgagca cgtaagccac cacaccagca atcacaccag ctaccaccag
     2761 ttggcccgtc catgttaaga aagtaatcaa tcgagtaatc atatctttta ttatagcaga
     2821 taaaaagagc ctgagactac tcaggctcca aaatatagat aaatccaatc ttcatgagaa
     2881 gctggactta tagcccataa ttgtaatcgt catcagtcat agcttcaaca gtaccaagaa
     2941 ggtagccatt accaacttga gagaagaaat cgtggtttga cgtgccggtt gaaataccat
     3001 tcataacgat tgggttgaca tcattggcag tgtctggaaa aagagggtcc tgaccaaggt
     3061 tcatcaaagc cttgttagcg ttgtagcgta ggaaggtcat cacttcctcg gtccagccaa
     3121 cctcatcata gagggtcttg gtgtattgct cttcattttc atatagctga tacagcaggt
     3181 catacatcca gtcacgaagg ctttcttgct cactctctga tagctcatta aagcccagct
     3241 gaaacttgta gccgatataa gtgccatgaa cggactcatc acgaatgatg agcttaataa
     3301 tttcagcgac attagccagc ttattgttgc ccagataata gagtggtgta aaaaagccag
     3361 aataaaatag aaaggtttcg agataagtcg aggctacctt tttttgaagg gcactgccat
     3421 tttcataaat gtcgttgatt atcttagcct tattttgaag aaatacgttg ttgttggtcc
     3481 actcaaaaat gtcttcaatt tcttttttgg tgtttagggt cgaaaagatt gatgagtagg
     3541 atttagcatg gacagactcc ataaattgga tattgttaag aactgcctct tcatgcgggg
     3601 tgcgcacgtc cttgcgaatg gcttcgactc ctgactcaga ctgcatcgta tcaagaaggg
     3661 ttagcccgcc aaagacctta cctactaaat ccttttcaac agcagataat ctgcgccagt
     3721 catcaaggtc atttgatagt ggaatacgtg tatcaagcca gaattgctcc gtcagctttt
     3781 cccaggttga cttgtcaatg acatcttcga tttcattcca gttgattgct tcatagtatg
     3841 tggtcatgag tttctccggt agattgtaat atagggttag gtatgctagg aggagagcct
     3901 tgagtgctgg tctatcatta ggacaggtgc actgacacat cagctaggct ctgacattaa
     3961 ggactggtcc acctcactgc cattcacttg gttagatgac acagctttca cactgattgg
     4021 ctccgacctc ctcgccatca tcggtaaagg tgcggatata atagattgat tttatccctt
     4081 tattaaaggc gtaatgtctc aaaatagata ggtcacgagt ggtttgcttg ctttctgttt
     4141 tccattcgta gagctccttt ggcaattcgc tgcgcaaaaa gagtgttaac gacagtccct
     4201 gatcaacatg ctttgtagca gctgcataga catcaatcac ctttctcatg tccatatcat
     4261 aggcagatgt gtagtaagga atggtgtctg tagataggcc gttggctggg taataaatct
     4321 tgccgatttt cttttcctga cgttcttcga tccgctgagt aatcgggtga atagaagcag
     4381 agcagtcgtt gatataggaa attgatccat taggagcaac tgccagacgg ttttggtgat
     4441 aaaggccatc tgtcataatc gcttgacgca gcgccttcca gtctgctgct tgcggaataa
     4501 agtgatcctt gaaaaggctt ttaaccagct ctgattttgg cacacattct cctgtgatgt
     4561 actggtcaaa ataagcaccg ctagcatatg ttgatttttc aaagccaaca aaggttgtct
     4621 gacgctcgcg agcgatctga ttggattcga caagcgtcca gtaattcatc agcataaagt
     4681 aaatatcagt aaattcgata gattctgggc tgccatattc gatatggtgc tgagccaaat
     4741 aggaatgaag ccccatagcc ccaaggccaa aggtatgtgc ttgactgtta ccatttttaa
     4801 cagttgggac tgcttcgata ttagaggagt cagtgacaaa ggtcagggca cgtgtcatgg
     4861 ctctgatgga acgaccaaag tcaggtgacg tcatcatgtt taagatatta gttgatccca
     4921 gattgcagga aatatcagtt cccattttga caaactcctg cgcatcatta atgagactag
     4981 gcgtttgaac ctgtagaatt tctgagcata ggttgctcat gatgatttta ccgtcaatag
     5041 ggtttgacct gttggcagtg tcgatgttga taacataggg atagccagat tcctgctgga
     5101 gcttggaaat ctctgtctcc aaatcacgtg ctttgatttt tgttttggtg atattaggat
     5161 tggcaaccaa ttcgtcatac atgctagtaa tatcaatgta gttaaatggc aggccgtatt
     5221 ctctttcaac actataaggg ctaaagagat acatgtcagc attgtgacga gcaagctcat
     5281 aaaacttatc tggtacagta ataccaagtg acaatgtctt gacccgcacc ttttcatctg
     5341 cattttcttt tttggtagac aaaaaagcga taatatcagg gtgaaagacg cttaaataca
     5401 ccacaccagc cccttgacgc tgccctagct ggttggaata agaaaagctg tcctcaaata
     5461 gcttcattac aggcacaaca ccagaagcag ctccggcata gcccttgatt ggagcgccag
     5521 cctcacgaag gttggatagg ctaatgccaa caccaccccc aatacgggat aattgcaagg
     5581 cagaattaat agagcggcca atggcattca tatcatctgt cacctgaagg agaaagcaag
     5641 aaaccagctc accacgacgg ctccgtccag catttaaaaa agaaggagta gcaggttggt
     5701 aacgctgatt aatcatctca atggctaagt ccttagctaa tgtttcatca ccatcagcaa
     5761 aataaagggc attgaacatg acccgatcct ctatgctctc taagtagaaa ttgccatcat
     5821 tggtttttag ggcatactgc tgataaaatt tataggccgc cataaatgat ttaaagcgaa
     5881 agccctctgc ttgaatgctc ttggctagat ggctgataaa ttcaggagaa tagttttgga
     5941 taaaggctga ttcaatatag tcattgtcta caagataggc aatcttttcg ttgatagaag
     6001 aaaatgacat ggtgttagga ataacatttt cggtaaaaaa agcctccaaa gcttccttgt
     6061 ctttatgaag tggaatgctg ccatcaacag gacggttaat ttcattgttg aggcgaaagt
     6121 aagaaatatc gccaagatct ttgagactca tatcaattgt tccttgtcta gttaaataat
     6181 atcttttaat tttgctggct gaaaccctga gaatactatc tgctctgtct caataacagg
     6241 agcagcagta aagccaaggc tcttaacata gtccactttt tctggatgct catcaatatt
     6301 aatctcttgg aaagcagctc catgctgttc taaaaatttc ttagtcattt tgcactgcat
     6361 gcaattgtgc tttgagtata ctgtaatcat tgctcgtcct tccaactatt agtctttcac
     6421 tcaattttag gaaaaatcaa atgactctaa taggatataa aaaatgttcc taaaaagcaa
     6481 acgatttatt tcagaatagc acaagatatt gtggttgtgt gtgagaatat ttctaaatat
     6541 tgtgttatcc tctcttatca ctgataattg ctacaagagg cttgtagttc ttaaatgcat
     6601 actaatcagg ttggaaggct tatttgacat tatgaaaatc atcatgtaag aaatattgac
     6661 aacaaatgaa aatacaagaa aactgtttca tgattttttc ttgttagaac atttaacctt
     6721 gaaaataaaa aagcattgtg ctataatcac ttattgtaag ggttatcatg tgatagctcg
     6781 aaaatacaca attcaaaagg agaaccatat tatggcttca aaagactttc acattgttgc
     6841 agaaacaggt attcatgcac gcccagctac cttacttatt caaacagcaa gcaaatttgc
     6901 ttcagatatt acacttgact acaaaggtaa agcagtaaat cttaaatcaa tcatgggtgt
     6961 tatgagcctt ggtgttggtc aaggtgctga cgtaacaatc acagcagaag gcgctgatgc
     7021 agatgacgct attgcggcaa tcgaagaaac tatgactaaa gaaggattgg cataagacta
     7081 tgacagaaat gcttaaagga atcgcagcct ctgacggtgt tgctgttgcc aaagcatatc
     7141 tgctagttca gccggatttg tcatttgaga ctatcacagt cgaggataca aatgcagaag
     7201 aagctcgcct tgatgttgca ctacaagctt cacaagacga gctttctgtt atccgagaaa
     7261 aagcagtaga aagcctaggc gaagaagcgg cagcagtttt tgatgcccat ttaatggttc
     7321 ttgctgatcc agagatgatc agccaaatta aagagactat tcgtgcgaag caaacgaatg
     7381 ctgaaacagg tctaaaagaa gtgactgaca tgttcatcac aatctttgaa ggcatggaag
     7441 acaatcctta tatgcaagag cgtgcggctg atattcgaga tgtcgctaag cgcgtcttgg
     7501 ctcatttatt aggtgttaag cttccaaatc cagctacaat tgatgaagaa gcaattgtta
     7561 ttgcacatga tttgactcct tcagatactg cacagcttaa caaacaattt gtaaaagcat
     7621 ttgtaacgaa cattggcgga cgtacgagtc attcggctat catggcccgt acacttgaga
     7681 ttgcggctgt gcttggtaca aatgatatta ctaagcgtgt caaagatggt gaccttattg
     7741 ctgttaatgg tatcactggt gaggttatta ttgacccaag tgaggagcag attcttgctt
     7801 tcaaggaagc tggagaggct tatgcgaagc aaaaggctga gtgggctctg cttaaggacg
     7861 cacaaactgt cacagcagat ggcaagtact ttgaattagc agcaaacatc ggtacaccta
     7921 aggacgttga aggtgtcaac gataatggtg ctgaggcggt aggtctttac cgtactgagt
     7981 ttctttatat ggattctcag gatttcccaa ccgaagatga gcaatatgaa gcctacaagg
     8041 ctgttcttga aggaatgaac ggcaagcctg ttgttgttcg tacaatggat atcggtgggg
     8101 acaaggagct tccttacttt gatttaccaa aggaaatgaa cccattcctt ggttttcgtg
     8161 ccttacgcat ttcaatctct gaaacaggta atgctatgtt ccgcacacaa attcgtgctt
     8221 tgctgcgtgc ttctgtgcat ggtcaattgc gtatcatgtt cccgatggtt gcccttctaa
     8281 aggaatttcg tgctgctaaa gtcgtatttg aagaagaaaa ggctagcttg ctgtctgagg
     8341 gtgttgcggt tgcagacgat attcaggttg gtatcatgat tgagatccca gcagcagcaa
     8401 tgcttgctga ccaatttgcc aaggaggttg acttcttctc aattggtaca aatgacctta
     8461 tccagtacac aatggcagca gaccgcatga acgagcaagt gtcatacctt taccagccat
     8521 ataacccatc aatccttcgt ttgattaaca atgttatcaa agcagctcat gctgaaggta
     8581 agtgggctgg tatgtgtggt gaaatggcag gtgaccaaca ggctgtgccg cttcttgttg
     8641 gtatggggct tgatgaattt tcaatgtcag caacatctgt gcttcgcaca cgtagcctga
     8701 tgaaaaagct tgattcagcg aaaatggcag agtatgctca tcgtgcactc acagaatgct
     8761 caactgctga agaggttctt gagcttgcca aagagtatat tacagaagct taaatagaaa
     8821 taacgaggag ctggttttgt ccggctcttt tttactagaa aaatgactaa tcagatccat
     8881 atgaaagctt gctttataaa gtagtttgat gtttcaagtt ttatcagaat tttcagactc
     8941 ttcctgtagc gaattgttga aatatgctaa aaaagtgata gaataatagt accattataa
     9001 aaggagaaaa aagtttggct aaacaatata aaaatttagt gaatggtgag tggaagctct
     9061 ctgaaaatga gatcaagatc tatgcaccag caaccggcga ggagttaggt agtgtaccag
     9121 ctatgtctcg tgaagaggtt gatcaggttt atgcgtcagc tcgcgctgct cttgcagatt
     9181 ggagagcgct ttcttatgtt gagcgtactg cttatttgca caaggctgct gatattttgg
     9241 tgcgtgatgc tgagaagatt ggtgctgttc tctcaaaaga ggttgcaaag ggttataagg
     9301 ctgctgttag tgaggttatt cgtacagcag aaattattaa ctatgcagca gaagaaggcc
     9361 ttcgtatgga aggcgaggtc cttgagggtg gcagctttga ggctgctagt aagaaaaaga
     9421 ttgcgatcgt acgtcgtgag ccagtgggac ttgtgcttgc gatttcaccc ttcaattatc
     9481 cgattaacct agcaggctca aagattgctc cagcccttat tgcaggaaat gtcgtggttc
     9541 ttaagccgcc gacacaaggc tctatttctg gcttgctctt agcagaggta tttgcagaag
     9601 caggtcttcc tgctggagtc tttaatacca tcactggacg cggctcagtt attggtgatt
     9661 acatcgttga gcatgaggct gtaaacttta tcaactttac tggctcaacg ccaattggag
     9721 agcgaattgg taaattagcc ggcatgcgtc cgattatgct tgagcttggt ggtaaggatt
     9781 cagcgattgt cttagaagat gctgatattg ccttagctgc taaaaacatt gttgcaggtg
     9841 cctttggcta ctcaggtcaa cgctgtacag cagttaagcg tgtgcttgtt atggaaagcg
     9901 ttgcagacca gctggtagca gagattaagg gcttagttga gaaattactt atcggtatgc
     9961 cagaggacaa tgctgacatc acaccattga ttgataccaa agcggcagat tttgttgaag
    10021 gtctggttaa tgatgcagca gacaagggag cacaggcgct tactgaaatc aagcgtgacg
    10081 gtaatttaat ttgtcctatc ttgtttgata gagtaacaac tgatatgcgc ttggcttggg
    10141 aggagccatt tggtccggtg ctgccagtga ttcgtgtaag ctctgtagaa gaggcaatca
    10201 gcatttcaaa tcaatctgaa tacggtttgc aagcgtctat ctttacgact aattttccac
    10261 aggcctttgc tattgctgag aagcttgagg ttggtacagt acacattaac aacaaaaccc
    10321 aacgtggtac agataatttc ccattcctag gggctaagaa atcaggagct ggtgttcaag
    10381 gggtcaaata ttcaattgag gcaatgacaa gtctcaaatc agtcgtattt gatattcaat
    10441 aacaaaaaag ctagggtatc ttagtttgaa agcagttgca catttgtgcg gctgttttat
    10501 ttgtgtctct agttttaaca gctagctatg caagaaggtg agttgtccca acctcaaaga
    10561 tgagatctaa atatttaatg attttggggt cgtaaaaaag tttagagtgt tttgatctcc
    10621 ttaagatgtg agtgtacaaa gtctcgccaa cagccagcag gactagccat tgaggtcaag
    10681 gaagctgcta aaatagctga tggttcaaaa gcttggtgaa aggcttaata tctatcattg
    10741 ctattttgag ggctttccat tataatatga atactagagc tacttgtcgg tctgcctctt
    10801 gagctgtgag atagctgttg gatttagttg tctccttgtc cacaaaaggc ttagaggcaa
    10861 aggctgtggc tatgcttctt gcttctttta gtgaagtgta tgagatctta tgaaaactca
    10921 tataggcttt ggtatctttg caagaggact aatggcttgc tttacttgcc ttgatagagg
    10981 gctgggattg aggggtgatg acctgcggtg gtcatctcta gagctccttg cttctttttt
    11041 tatgtagact aatggtttag actgctagct tccttgttta gaaagtagga catcatgtta
    11101 cccaagagaa aattaattga tcaacgtctt gattatgcca ttatttttcc tgttttttgt
    11161 ttgctaatat ttggtctggt atctgtatat gtggcagcaa gtcatgattt tccgcaaagc
    11221 ctcgccactg ttatgcttca acaggttctc tggatccttc ttggagctgt gattgccttt
    11281 accctaatgt tttttagcac agagattctg tggaaattaa cacctgtctt ttatcttttg
    11341 ggtgtgctat taatggttct gccactcatc ttttttagcc ctcggctggt agctgctaca
    11401 ggggcgaaaa attggattac gattggctca acgaccttgt ttcaaccatc agaatttatg
    11461 aaaatatcct acattctggc aatgtcttgg ttaacggtct ggtttaagag aaagcaggag
    11521 agaagtcggt ttttagatga ttggaagctc ttgggcttat accttgtctt gacgttgccg
    11581 gtcatggtcc tgctagcact gcaaaaggac ttaggaacag ctatggtttt tttagccatc
    11641 ttagctggga ttatcttaat ttcaggaatt tcttggtggc ttattttacc agctttggta
    11701 ctagtctttt tactggtttc agcttttttc tttgtttttt tgttgccaga gggaaaagaa
    11761 ttccttttaa aaatgggaat ggatacctac caattgaatc gtatttcagc ttggctgaca
    11821 ccgtttgatt tctcagatac cattgcctat cagcagacgc aaagtatgat ttcgattggg
    11881 agtggtggct tttttggtaa gggctttaat cagcttgagc tgtcagtacc agtcagagaa
    11941 agtgatatga tttttacagt gatcgctgaa aattttggct ttcttggtgc agctagctta
    12001 ctgatcttgt atttaatact gatttaccgc atgcttaggg tgacctttgc atcgaataac
    12061 cttttttata cctacatttc aaccggcttt atcatgatga tactatttca tatttttgaa
    12121 aacattggcg cagcagttgg tctgctacct ttgaccggta ttccccttcc ctttatttct
    12181 cagggcggct cttccttgat ttcaaatctg attggggtcg gcctgatcct atcaatgaac
    12241 tatcagcacg tccttgctca tgaaaagcaa agcgagcatg agcttagcag aagctcacgt
    12301 tatgtttaag aggcatgttt ggtccttgtt cggttagaat gagctgccaa tcagcccttt
    12361 tttatttgct taatcgctat aaaaataaag aaaaatatgt tataattaag gttatgaatt
    12421 atcatgatta tatttgggat ttgggcggca ctctcttgga taactatgaa atttctaccc
    12481 aggcttttat tgagacgctg cattttttta agctgtctgc aagccacgat gccgtttatc
    12541 aaaggcttaa gaaatcaaca gcaaccgcca ttcaagtatt tgctcccaac gaaccgcaat
    12601 ttttacaata ttacaaagcg aatgaggcta agaaattagc caatcctatt tggtgcctag
    12661 gtgcaaagga cattctaaag aggattgtgg catcaggctc gcgtaatttt ttaatatccc
    12721 atcgtgatca tcaggtcaat gatttgctgg agcaggctgg gcttttgggc tattttaccg
    12781 aggttgttac cgcctcaaat ggctttgcca gaaagcctaa ccctgagagc ttactttatt
    12841 tgaaggaaaa gtacctgatc agcaagggct tagtgattgg tgatcgcaga cttgatatag
    12901 aagcaggaca agcagcaggc tttgacaccc tgcttgttga tggtagaaaa aacctattgg
    12961 agatagtaga ttagatggtt gaagaaaata aacaattaga agacaaggct caagagtatg
    13021 acgctagcca gattcaggtc ttagaggggt tagaagccgt tcgcatgcgt cctggaatgt
    13081 atattggctc aactgccaag gaaggcttac atcacctagt ttgggagatt gttgataatt
    13141 ctatcgatga agccttggca ggctttgcca gtcatattca ggtttttatt gaggcagata
    13201 attcgattac cgttattgat gatggacgtg gtatcccagt tgatattcaa gctaagacag
    13261 gccggcctgc tgtagagaca gtttttacag ttttgcatgc cggtggaaaa tttggcggtg
    13321 gtggctacaa ggtttctgga ggacttcatg gtgttggctc ctcggttgtt aatgccttat
    13381 ccacacagct tgatgttcgt gtctataaaa atgggcatat ccactatcag gagtttaggc
    13441 gtggtgctgt agttgatgat ttggctatca ttggaacgac tgatgttacg ggaacaacag
    13501 tgcatttcac acctgatcca gagatcttta cagaaacaac agaatttgac taccaggtcc
    13561 tggcaaagcg tattcaagag ctggcctttc ttaatcgtgg cttaaaaatc tcaattacag
    13621 ataaacgagc tggtcttgaa agagaagagc atttccatta cgagggtggt attggctctt
    13681 atgttgcctt tttaaatgac aaaaaggacg tcatcttcga tactccgatt tattctgatg
    13741 gtgagctgga ggggataaca gttgaggtgg cgatgcagta cactacaggt taccatgaga
    13801 ctgttatgag ctttgccaac aatattcaca cacatgaggg tggtacccat gagcagggct
    13861 ttagaacagc tctgacgcgc gtgattaatg actatgctaa gaaggctaag attctcaagg
    13921 aaaacgagga taatctgaca ggtgaggacg tccgcgaggg cttgactgct gttatttctg
    13981 tcaagcaccc aaatccacaa tttgaagggc aaacaaagac aaagttagga aattctgagg
    14041 ttgttaagat taccaatcgc ttgtttagcg aagctcttca gcgctttcta ctagagaatc
    14101 cgcaggttgc ccgtaagatt gttgaaaagg ggattctagc ctctaaggct cgcattgctg
    14161 ccaagagagc gcgtgaagta acccgcaaaa aatcaggcct agagatttcc aatttgccag
    14221 ggaagctggc tgactgctcc tcaaatgatg ctagtcaaaa tgagcttttt atcgtggagg
    14281 gggattcggc tggtggatca gcgaagtcag gtcgcaatcg tgagtttcag gctattctgc
    14341 ctattcgtgg taaaatttta aacgttgaaa aagcaacgat ggataaaatc cttgctaacg
    14401 aagaaatcag aagcctcttt actgctatgg ggacaggctt tggagcggag tttgatgttt
    14461 ctagagctcg ctatcaaaag ctggtcatca tgactgatgc agatgtcgat ggagctcata
    14521 tcagaacgct tttgttaacg ttgatttatc gcttcatgcg accagtatta gaggctggct
    14581 atgtttacat tgctcagcca ccgatttatg gtgttaaggt tggcagcgag attaaggaat
    14641 acattcaacc gggagtcaac caagaagagg agctaaaggc tgctcttgaa agacatagca
    14701 caggacgctc aaggccgact attcaacgct ataagggcct aggagagatg gacgatcacc
    14761 agctttggga aacaacaatg gaccctgata atcgtctaat ggcacgtgtg accgtagatg
    14821 atgcggcaga ggctgatcgg atttttgaca tgctgatggg cgatcgtgtt gagccaaggc
    14881 gtgaatttat tgaggaaaat gcggtctata gtacgcttga catttagtca aatatatttt
    14941 gaaaagcacc taaaagtatg ttataatcgt aacgttatag tgtatttttg ataatataat
    15001 aaaaggcgat tcttgctagt tgttcctact gaaccggcag ttgatcaatc gcatctaaat
    15061 aataaggaga ttaagatgtc aagcggaatt atcttgctga ttgtggccat agtcttacta
    15121 gtgattattg cttatttagt gggtgttatt atacgcaagc gtaatgacac attaattacc
    15181 agtctagaag aacgaaaaca agctttattt ggccttcctg ttaatgacga aatcgaggaa
    15241 gtcaagtctc ttcacttgat tggtcaaagc cagacctcat ttcgtgaatg gaatcaaaag
    15301 tgggttgatt tgaccctaaa tacctttacc gatattgaaa agcatatctt tgaggctgag
    15361 cacttaaatg acacctttaa tttcattcgt gccaagcatg agattaatag cgttgagagt
    15421 caattgaatc tcgttgaaga ggatattacc gctattcgtg aagcacttgg catattaaag
    15481 gagcaggaag aaaaaaacag cgcgcgtgtt actcatgcac tagatttgta cgaaaagttg
    15541 caggcttccg ttgctgaaaa tgaagataat ttcggatcaa caatggccga aattgaaaag
    15601 caaatgaaga atattgaagc agagttttca caatttgttg cccttaattc atcaggtgac
    15661 cctgttgaag cagcggaggt tttggataag gctgaggagc atacgattgc cttggggcaa
    15721 attacagagc agatccctgc tattgtagca aagcttgaag atgattttcc ggatcaattg
    15781 gacgatctgg agacaggcta tcgtcgtttg ctggaggaaa attatcactt cccagaaaaa
    15841 aatattgaag cccgctttca agagattcgt gagtctattc gtgccaattc atcagagctg
    15901 gttacccttg atttggaccg agctagagat gaaaatactc acattcaaga gcgtatcgac
    15961 tcactgtatg agctctttga gcgtgagatt gcagcctaca aggtggttgc taaaaatagc
    16021 aaaatattac caagatacct ggctcacgcc aagcacaaca acgagcagtt gaagcatgag
    16081 attgctcgtc tatcacgtaa gtatatcttg agtgaaaatg aaggcttaaa tatcaaggcc
    16141 tttgacaaag acctcaaaga tatcgaagac aatgtccttg agattgctga agcctttgat
    16201 cagcaggaaa agccattttc agagctacag ctgattcttg atcgtagtat caagacgttg
    16261 gcttctgtag agtctggtca gatggacgtc tttgctgctg ttaaagacat tgaaaagatt
    16321 gagtcacagg ctcgccagca cttagaaatc tacgtcacac agcttcacat gattaagcgt
    16381 tatatggaaa agcgcaattt accgggaatt ccacaggatt ttctgagtac cttctttacc
    16441 actagttcgc agctagaagc attgatggac gaactaagta gaggacgtat caacattgaa
    16501 gcggtgtccc gtctgtctga ggtggcaaca gctgctattg ctaatctaga agagctaacc
    16561 taccaagtgg ttcagcatgc taccttgaca gagcagctgc tccagtactc taaccgttat
    16621 cgttcctttg aagctggcgt gcaaaatagc tttgagcatg ccttgaaatt gttcgaggtg
    16681 gacaatgact atcaggcatc atttgatgag atttcctatg ccttggagac agtcgagcca
    16741 ggagtgacag agcgttttgt caattcctat gagaagacac gtgaacgtat ccgcttctaa
    16801 tgtgacaagg gttgatactt tatattacga aaaagcttga aaaagcagtc catgctgggc
    16861 tatgcttttt caagcttttt gaatggtcag gctatggcct ccttgagcta tacccaaaaa
    16921 gctggttcaa gccagtcagt agagatagac aaggccttag tgctattggg ctgttgctac
    16981 atgagatatt ttgtaataaa atcagacgat tatccattta attaaaaaaa aaaaaaaacg
    17041 aaactgcgga ggaaacctga cgagtaacta tttatggcta tcaatcagca tgttacactc
    17101 tttttggaag gcctagcaat cactgactgt gaggttaacc aaagaaaata agatgttaag
    17161 gagaatatca atgaaaataa ctaaagcatt gtgtgtagca ggtgctgttg cagtcctagc
    17221 cttggcacca atcagctcaa gtcctgcacc aacacagact gtatttgctg ctacacgtgg
    17281 tactgaagag tactgtcata atgggtggtg cagttttctt gatgaacatg gtgagtggaa
    17341 cacgaaacgt gagggcgaat ctaatagtcc cctacagcga ggttcatggt gggattggat
    17401 ttcttattgg tctggttata tatggtattc tgtatataac tggtttaggt aacctctcaa
    17461 cgccactgct accatactga taaatccctt agactattct aagggatttt tactgcaaaa
    17521 agcacatagg gacaaggcaa tacaagctcc agcctgttct tagctcccta taccggtaag
    17581 gatcataaca ctcagaactc cggcagatga ttgcaggagc tattggagag tgaggactag
    17641 tgaaagagcc tctgccagag ggatttgccc ttagtctttg tttgttcagc aggcttattg
    17701 tcagagggct tgtctagtat agccttgaga ttggtttcct ctttggtgat ggcatgatca
    17761 ctatgaatga tcagagcaaa aggagagaca gctcctttct catctacaat agtggcagat
    17821 agagcgtttt gttgggccaa tttcatatag tacatttgat aagcagagcc gaattcagag
    17881 gataatttga atgacaaggg gaaataagcc tctttgaggt gaggcagctg ggctgtgatg
    17941 tagcctttag ccttttcatg atcaacctct gtcaagggaa gcgctaagac aatcctttca
    18001 gcataggtcc ctaaataata gcgttgttgg tcggggtcaa atcggttttc tcctgaagct
    18061 ccctttaaga gtcttgtatc taatgaatcc atacaatcct ttcaagcatg tgatactgtc
    18121 attatactat taactgcgcc aaataccaat gataaagcat ttactaggta tttgatcggc
    18181 ttttggaaga agatgaaatc aaagaaaaac agcatgaaaa caactctctt atttcatgaa
    18241 attagttttt aagttgctta agaccctagt ttgtggtatt attaacatgt aaaatattaa
    18301 aactcataag gagagtatta taatgtcaat tattactgat gtttacgctc gcgaagtcct
    18361 tgactcacgc ggtaacccaa cacttgaagt ggaagtttat actgaatcag gtgctttcgg
    18421 acgtggtatg gttccttcag gagcttctac tggtgagcat gaagcagtag aacttcgtga
    18481 tggcgacaaa tctcgttacc ttggtcttgg tactcaaaag gcagttgaca acgttaacaa
    18541 cattatcgct gaagcgatca ttggttatga tgttcgcgat caacaagcta ttgacagagc
    18601 catgatcgct cttgacggta ctccaaacaa aggtaagctt ggtgctaatg ctattcttgg
    18661 tgtgtctatc gctgtagcgc gtgctgctgc tgactacctt gaggtgccac tttacactta
    18721 ccttggagga ttcaatacta aggttcttcc aactcctatg atgaatatta tcaacggtgg
    18781 ttctcactca gacgctccaa ttgctttcca agagttcatg attatgccag ttggtgcacc
    18841 taccttcaaa gaaggtcttc gttggggtgc tgaggtattc catgctctta agaaaatcct
    18901 taaagcgcgt ggacttgtta ctgctgttgg tgacgaaggt ggatttgctc ctaaatttga
    18961 aggaactgaa gatggtgtag aaacaatcct taaggctatc gaagctgctg gctatgaagc
    19021 tggtgaaaat ggtatcatga ttggttttga ctgtgcgtca tcagaattct acgataaaga
    19081 gcgcaaagtc tacgactaca ctaagtttga aggtgaaggc gctgctgttc gtacatctgc
    19141 agagcaaatt gactaccttg aagaattggt taacaaatac ccaattatca caatcgaaga
    19201 cggtatggac gaaaatgact gggaaggctg gaaagcactt actgagcgcc taggcaaacg
    19261 tgttcaattg gttggtgatg acttcttcgt tacaaacact gaataccttg ctcgtggtat
    19321 caaagaaggt gcagctaact caatccttat caaggttaac caaatcggta ctttgactga
    19381 aacctttgaa gctatcgaaa tggctaagga agctggctac actgctgttg tatcacaccg
    19441 ctcaggtgaa actgaagatt caacaatcgc tgacatcgca gtggcaacaa acgctggcca
    19501 aatcaaaaca ggttcattgt cacgtactga ccgtatcgct aaatacaacc aattgcttcg
    19561 catcgaagat caacttggtg aagttgcaca atacaaaggg atcaaatcat tctacaacct
    19621 taaaaaataa tttgatttta gattaaaagg ttgacaagcc ttgattttaa agcattctag
    19681 gactgtccta gagtgctttt agttttagct tcatgtcaac tgtagtgggt gactgatagc
    19741 taagcacgag aggagacgaa ggtcgccttc tctttttcaa tcggataagg ctagggaatc
    19801 cccaaatgtc gatgaaggga attttagaag gtttctggaa gtcgtatatg atttgtttcc
    19861 ctttgcagtg tctacaccta ggagactgat agtccagtgt agcgctgact tcgatatgag
    19921 tatcgtgctg gatagtctta ttcaaggtga tattttgatc tttgattccg atgagtagtg
    19981 tggtatgatg aatctgttcc ataagacact ttctaatgat ggtctggtcg cttttcatga
    20041 taagccttat ggaacttttt gggtactcaa aaagccctat aatcttcata atgaatttac
    20101 ccattacaga aattatagag ccaatattta gaggatttta gcctattggt agattgacag
    20161 tttcttaaga ttgtgttaca atgtaacaca aagaaacgag gtaaacgact atgagtacag
    20221 ttactatcag attaaatcaa gaagaagaaa tatttttcaa aagttacgcc caactcacag
    20281 ggcaaagttt atcaagtcta tttaaaaaag cccttgagcg ggatattgaa gatgagtatg
    20341 atttaaaaat ctatcatcaa gcctatgctg aatataaagc agaccctgag acaattagcc
    20401 atgctgattt taagaaagag ctaggcttat aacatgtacc gtatagagta ttctaaaaag
    20461 gctcaaaagc agattaagaa agtagataag caaattcaga ggttgctatt tgcttggatt
    20521 gataagtatt tagagggaac agataaccca cgcgcaaatg gcaaaggttt gaccggaaat
    20581 catgctaatg agtggcgtta tcgtattggt gattataggc ttatttgtga tattcaagat
    20641 gataagatgg ttgttttagc gcttgagttt gggcatcgta aagatattta ctaacgttga
    20701 ggaagtaaga tggtcaaaaa taatgcaatt ggtagcaact ggaaagatgt aagagctgag
    20761 ttattcagca aggaagaatt ttagaaagtg atgctcgtat tgctattatg gacaagtata
    20821 gttaaaaagt gtgcgttttt aatctgtatg atgaagtaat tgataaagta acaggtcaaa
    20881 aggctatcat tgtctgtatt gctaataaat tggtagatga ttgttattta atcgaaccgc
    20941 taaaccattc ttacttacca gattggcgtg agataaatca gttaattcga tataaaaatt
    21001 agcaccttat cgggtgctaa ttccttgcct gctgaactca taatttaata ccttttttac
    21061 taccccatat gtttccccta attatgtgta cttgctagat ataaggttaa ttgggataga
    21121 attttgaata aagttgttgt attttgtaat agtgattgat attgggataa ccttaaaaaa
    21181 ataatttgat tttagattaa aaggtttaca agctttgatt ttaaagcatt ctaggactgt
    21241 cctagaatgc ttttagtttt gataagcaca atccgctgtt gactgtataa accgtatatg
    21301 atacaaaata agagcttgta gcagtgaagc cactaactct agtgctgtgg gctcaacctt
    21361 gattgatgaa tcccttgctt ttaatgcgtt tatgaagcag tggcgtatca gtctagctcg
    21421 ttgtggaaag caattaacta gagaagaatt actatcctca atcaatatgc tgacagccgc
    21481 agggatttgt gagtttgatt tgctgtggca gcgtcttgct cctaaggggt gtcagcgtcc
    21541 caaatggagc catcagctgg agaggctctt tgcggataca aagccttgtc tacaggtctt
    21601 gtctgagact tatcagcttg ggattattgc taatcaggca aagggtctaa aagagcgctt
    21661 agagaggttt gggattagtc attattttgc ccttatgata tcttcttctg atgtggggct
    21721 acaaaagcct gatcttgctc tgtttcgcta tgcacttgat caagcaggcg tattagcgcg
    21781 tgatgctgtt tatattgggg atcgtgttga caatgatatt attcctgcta aggcattggg
    21841 aatgagagct gtcaggattc atcaagggct tgctgcgtcc agtccagatg ataggcttta
    21901 tcctagtgat gtccatatta gcaaacttag tgacctgtta gaatgctttt aaccagtctt
    21961 tagcttgaac tagcttttct ttgtggtctt tctgggtgaa tggcagcaag ctttggagtc
    22021 atgttatggc tagaccttgg atctaagggc gctgagcgtc tcatatgatg aggccgatca
    22081 agtagtctcc ttgacaagta gattattgtt tggtgcttat aggtggcttt aggtgatgac
    22141 tggttttgcc tcaactaagg ctcgctattg ctatctgggg tatcttctga cttttttaat
    22201 gtgctcttat ctggttggat tagacctgct ccttgcttga ggaaagctgt ttttaacgct
    22261 gatgagtctg ggaaatggtg agattggtgt tggcttttac tagttttttt gcgtttactt
    22321 gggctaactt tatatgagaa aaaaagaaaa atatttattt tatctgttat ttttgttaca
    22381 ataagcgtgt aaactaagat gcattaaaaa ggagttttta tgtcgaataa gaaatttttt
    22441 acttatgctt cattattggc attaatcgct gttcctactg tggttgaaga ggtgactgca
    22501 cagccttcag ctcagcttgt ttatgcagat gagctaaggc tatcaccaag taccgactca
    22561 tctccagtaa caaagaccga tgaggctgat cagccagttg ctcaatctgt ttctgcgaca
    22621 gaaccagtag aggctcttgt tattgcggat aaagaaagcg ctttaaatcc tgctgttcta
    22681 gctgatgccg atggaagtca gccgattgca gtggttagag ctggtcaaga gggtcagcct
    22741 tataccgtta ctggcaaaat catcagtgct gttaatggct ggggtggtca tggcttttat
    22801 atccaggaca gtcagggatc aggtctttac atttatccag gaagtgcttt ggggtacgtg
    22861 actggtgatg tggtgcagct gacaggaaca ctgactactt acaagggtga gcttcagctt
    22921 aaaacgatta caaagcatca taagattaat ggcgaattac caacacctat tgctgaggta
    22981 accattccgg agctagaaaa agcaagcccg tctaccctgg tgaagctttc aaatgtgact
    23041 gttggagaca tttcatcaga taagcacgaa acctcctctt ttaaggtcag cgatacagct
    23101 ggcaatagtg ttgcggtgcg tcttgataat cgtacaggtg ttaagacctc tgacttactc
    23161 tctaaaattg gcaagggtga tgtgattaat ctgacagcta ttcactcaac ctttgatggg
    23221 aagctccagc tcaagccctt tagccttgag caatttgagg tagtaaagaa ggttgttcga
    23281 gaagaagagg tgactcctct tggtcgagtg gttaaaatcg gccaaattca aggtgccagc
    23341 cacacctcac cgctcttgaa tcaagctgta acagtaaaag aggtggtggt gacctatcct
    23401 gatgatgcaa ctcatttcta tgtgcaagat attaatggtg acaacgataa ggcgacctca
    23461 gacggtattc gtgtctttgc tcaaaatgct caggtgcagg ctggtgatgt gctgaccatt
    23521 tccggaacag tggaggagtt ctttggcaaa ggctacgatg accgtaagca gacggatctg
    23581 accattacgc aaatcaaggc atctaaggtc actaaaacag ggactgctca ggtaccagct
    23641 ccgcttgtgc taggtaagga tcgtgttgct ccagctaata tcattgataa tgatggcttt
    23701 agtgtttttg atccagaaga ggacgctatt gatttttggg aatccttgga gggaatgctt
    23761 gttgccgttg ataatgccaa gattttaggg ccgatgtctc ataaggaaat ttatgtgtta
    23821 ccagggtcat caactcgagt gctgactaac tcaggtggta ttttacttcc tgagacaggc
    23881 tataatacag acctgattcc tgttctcttt aaaaaaggaa agcaaaccat caaagctggt
    23941 gattcctatc agggacgact tgcaggtccg gtatcatata gctatggtaa ttataaggtg
    24001 tttgtcgatg acagcagtcg tatgccagtc ttggttgatg gtcagctgaa gcctgaaaag
    24061 acacacatca agaaggacct tagcaagcta agcattgcct catacaacat tgaaaacttc
    24121 tcagcaaacc catcatcaac aaaagacgag aaggtaaggc gcattgcaga atccttcatc
    24181 tatgacctaa atgctcctga tattattggt ctcatcgagg ttcaggacaa taatggacct
    24241 actgatgatg gcacaacaga tgcaacacaa agcgctcagc gcttgattga tgccatcaag
    24301 gccttaggtg gaccagctta tcaatatgtg gatattgctc cggaaaataa cgctgatggt
    24361 gggcagccgg gcagtaatat tcggacaggc ttcctgtatc agccaggacg tgtcagcctt
    24421 tctgataagc ctagaggtgg tgttaatgat gcggtgaaat gggtaaatgg tgagctaagc
    24481 ttgagtgttg gacgtattga cccaacaaat cctgcttgga atagtgttag aaaatcattg
    24541 gctgctgagt ttattttcca aggccacaag gttgtggtgg ttgccaatca tttgaattcc
    24601 aaacgaggcg acaattcatt atatggacgt gttcagccgg taacctttaa atcagaggaa
    24661 agacgtcatg tcttagcaag gcttttgagc caatttacta aggaaggtgc tagtcagcag
    24721 gctaatatcg ttatgttggg tgactttaac gattatgagt ttacgaagac cattaagctg
    24781 attgaagaag gagatatggc aaatttggtg agcaggcatg agctttctga ccgttattct
    24841 tacttctata gaggaaataa ccaaacgctt gataacatgc ttgtttcacg caatttgctt
    24901 ggtcgctacg agtttgacat ggttcatgtg aattcaccat ttatggaagc gcatggacgt
    24961 gcttctgatc atgatccgtt gcttcttcag ctctcctttg gaaaagacaa gccagcagca
    25021 ccatcagatc agccaaagaa aacaccagca ccagctgcga caactcaagc ctctaaggca
    25081 ggacgtgcac agctattgcc aaaaacaggt gataagacag cgcttatggt aagtatttta
    25141 ggcttaacag ctgtctttag ctcctttagc ctgtttagga aatgtcagga aaggaagtaa
    25201 aggatttctt tggggtaggc cagcagctga gcggctactg cgttttgtct gctggtgcta
    25261 tataggtggt tgaagcgagc gaagagaggt atgcttccta ggatcatagc acaatatctt
    25321 atgcttataa acgaacacaa tgctccttat gagcattcaa aacctatact caaaaggaat
    25381 ataacagctg agttaagagg gattgctttt gacagattgt ggtaaaaaaa gggatcttga
    25441 ggaattggct agtgatctag ctgccaaaat gcgatgtctt gtttgactat ttttccctat
    25501 tgggatataa tgacaataga aaaagggtag ttgtttgcgc aactaccctg tgcagaaccg
    25561 tttaagacgg tggcagaatg aaagttaaaa aataatcgtc gacctaccaa agttcagacg
    25621 gttatttttt attgtttaat atgacgattg caacgactaa gctgattaag gtaagtaaga
    25681 aactaccaaa agccagcatg agttgaaggg cctcgtaagt agacaataaa acgctccttt
    25741 cagttggatt ttgatgcatt gcccataggc atcaccacct ttcagaaatc agagccaccg
    25801 tcttagcttt tctgtaaaga acattatatc ataatcacat gagaaagccg ttagatttta
    25861 aactgatcag gcggcttttt ggtgttttgc tgtcttttag tggaatcgcc taagctttgc
    25921 tgtatagtat gggattttat gctttttgta agggcttagg ctgctatggc agggtccatg
    25981 tcctttgtca atagcttagt tttatggtac aatgtaggcg ttgcctagca acccttggtg
    26041 cttagttccc tttcaccaag catattacaa acgtggcgga gctgtttatg ctctagtctg
    26101 acgtcaaagg agaaacacat gacaagtttt actgttcgtg actatgttta cattgctcta
    26161 gtggctgccc tttatgtggt tttgacaatc actccacctt tgaatgctat ttcctatggc
    26221 atgtatcaat ttcgggttgc cgagatgatg aattttttgg ctttttacca taaaaagtat
    26281 atcattgcgg tgaccttggg ctgtatgatt gctaattttt atagctttgg cttgattgat
    26341 gttttggtgg gtggaggctc aacgctcatt tttgttagct taggtgtcgc tttatttaag
    26401 caataccaag aggaatatct cttaaatggc ttgctgaata aggcctttgt ttatttctca
    26461 ctattttttg cgacttctat gatcaccgtt gcgattgagc tttacttctt tggagcacca
    26521 tttttcctaa cttggtttac cactgctgta ggggaatttg cttcacttat cattggctct
    26581 atgatcattg atcgcttatc aaaacgcatt aatttacgac aataatagta acatgtagcc
    26641 ttccgttttt gggaggcttt ttatgatttt cttctagcta ggcaatagct tatttgctat
    26701 gttttgtgat aaaataagac tatgaaaaaa cgcataagag aattgactga tctgttaaat
    26761 caataccgtc aggagtatta caccaatgac gctccttctg tatctgatag tgagtatgat
    26821 aagctttatc gtgagcttgt agagctggag cagacctatc cagcctatat cctaaaggac
    26881 agccccacac agctggtggg cagtacgatt ttgacaggat ttcagaaata tcagcaccag
    26941 tatccgctct ttagtttgca ggatgctttt tcacgtgaag agcttaacgc ctttgatcag
    27001 cggatcaaat cagcctttcc tgaggctgaa taccttgctg agctaaaaat tgatggcttg
    27061 tccatttcgc tggtttatga ggctggtgtt ctaaaggttg gagcgacacg tggcgatggg
    27121 actattggcg agaatatcac tgaaaacatt aagaatatta aggatattcc caaacggcta
    27181 agtcaagcac ttgatgtgac gatacggggg gaggcctata tgtcgcgtca ggcctttaag
    27241 acgatcaatg aagagcgtca ggaaaatggt gagccagaat ttgccaatcc aagaaatgca
    27301 gcggcaggaa ccttgaggca gctggatact aggattgttg ccaagcgaca gctagcaacc
    27361 tttttgtatc aggaggtagg cctagaaact gctgatagcc agcaaaagac cttggagcgc
    27421 ttggccgatt taggcttttc ggtcaatagc cactatctgc tgtcctcatc gatgaatgac
    27481 atttgggact ttatccagag cattgaagct agtagagaag agctacctta tgagattgat
    27541 ggtgtggtgg tcaaggttaa tcagttggcg atccaagagg aacttggctt taccgtcaag
    27601 gcaccacgct gggctattgc ttataagttt ccagcagaag aaaaggaagc tgagattgta
    27661 tctgtggatt ggacggttgg ccgaacaggt gtggtcacac caacagctaa tttgacccct
    27721 gtgcagctgg caggcaccac tgtcagtcga gcgaccttgc ataatgttga ttatatcgca
    27781 gaaaaggata ttcgcattgg ggatacggtg gtggtgtata aggctggaga tattattcca
    27841 gctgttttgc gggtggttga ggctaagcgt agggatcagg ctccaatgcc cattcctaca
    27901 gcctgtcctt cctgccagag tcagctggtg cattttgagg acgaggtagc tttgcgttgc
    27961 attaacccct tgtgtccgag cttggttcaa cggagcttgg agcattttgc cagtcgtcag
    28021 gcgatgaata tcgctggtct tggtccagcg gttgttgaaa agctttattc tgctggcctg
    28081 gtgcatgatg tggcagatat ttaccgacta agcttggagg atttgctgac gctagatggt
    28141 atcaaggaaa agtcggctga aaagctcttg gcagctattg aacaatcaaa ggcaaactca
    28201 gctgaaaagc tcttgtttgg acttggtatt cgtcatattg gcgcaaaggc tagtcgtctg
    28261 atattagagg cttacggtga tttagaggcg ctgttagctg taaccgctga agagctcgct
    28321 cagattgacg ggcttggtct agtgatcgga caatccctgg tgcagtattt tcagcaagag
    28381 caagccgctc agctgctagc tgaattaaaa tcagctgggg ttaatctggc ttatttaggc
    28441 caaaggcctg atcaacaggc tgcgctgttt ggtttaacgg tggtattgac aggaaaatta
    28501 gaaaagctaa accgtaccca agccatggaa aagctagagc agcttggtgc taaggtaaca
    28561 ggaagcgttt ctaaaaaaac agatttagtg gttgctggca gcgaggcagg ctctaagctg
    28621 gctaaggccc agcagctggg tatcagaatt gaagatgagg attggttgct caatctttag
    28681 tgaggtaata acatgaaaaa acaaatgagg gctcgtctga tttacaatcc aacctctggt
    28741 caagaaatca tgaaaaaaaa cgttgcagag gtgctggata ttttggaagg ctttggctat
    28801 gaaacctctg cctttcaaac gacagcagct aagcactcag ccttaaagga agcaagaagg
    28861 gcagctaaag caggctttga cctcttgatt gctgctggtg gagatggtac gatcaacgaa
    28921 gtagtcaatg gcattgctcc cctagagaaa agacctaaga tggcgattat tccagcagga
    28981 accaccaatg attttgctag ggccttaaag gtaccaagag gcaatcccgt tgaggccgct
    29041 aagctgattg gtaaaaatca aaccatccgc atggatatag gacgtgctaa aaaggatact
    29101 tattttatca acatttcagc cgcaggaagc ctgacagagc tgacctatag tgtccctagt
    29161 cagctcaaaa ccatgtttgg ctacctggct tatctggcta agggagtgga gctcttgcct
    29221 cgagtgagta atgttccggt gaaaatcacg catgatcatg gcatttttga gggagaggta
    29281 tcaatgattt ttgcagccat cactaattct gttggtggct ttgaaaagat tgccccagat
    29341 gctaagctag atgatggcat gtttaccctt attttgatta aaacagccaa cctgtttgaa
    29401 attgtgcacc tgctgcggtt gatcattgac ggtggtaagc atgttacgga tcgccgcgtc
    29461 gaatacatta aaaccagtaa aatcaccatt gagccccaat cagataagcg catgatgatt
    29521 aatttagatg gtgaatatgg tggtgatgcg ccaattaccc tagaaaactt aaaaaatcac
    29581 atcacctttt ttgcaaatac tgatttgatt tcagatgatg cccttgtcct agaccaagag
    29641 gagctggaaa tcgaagaaat ggtcaagaaa tttgcgcatg aggtagagga tttagagcag
    29701 ggattggagg aatagggcta gttatggata atgcagttat tgttcattat catagttgca
    29761 agggacatta ttttcaatta agtctatggc aatggcgaga tggtaagctg ggcaaggacg
    29821 cttatttttc gaggtttgac agctttggag cagttgctta tctcacttat ccagcacctt
    29881 attttttgag tcatgcttat gtgattgtaa aggatcagtt ttggcagcat caaaccgttg
    29941 attttcggat tgagcgtgat tatggggttc caaagactga ggtgtggctt gttgatggtg
    30001 atcctacggt ttattattcg agacaggctg ctgtggctag tcgacatgat ggtagatgtg
    30061 atgtgcatgc ctttgatatg gctgtcaata gtcaggcctt tgacaagcgc tggggcttta
    30121 gtggctggct aggctttcgc tatcagcctg aggagacgtc ttttcgtttg tgggctccaa
    30181 cagcagaaaa ggttgagctc attctctatg cttcgactga tgagagagct agtgttgcca
    30241 aggttttgcc catgcagcgt gggcagcagt actcgccaga tcatcatgca gaaaacacat
    30301 gtggtgtgtg ggacatcagc ctaagaggtg attataatta ccatgcttat tgctaccggg
    30361 tttattatcg caggcgtacc tttagagaca ctagggatcc ttatgcgatc gcaacgacag
    30421 caaatggcaa aaggtcaatt gtcattgcac cggagcattt aagaccgcag ggcttttcag
    30481 tgaagcaggg taaggaggct acctggcgct tagacaatcc taatcaggcg gtgatctatg
    30541 aaatgcatgt tcgcgacttt tcaaaatcag aaacctcggg cgttagcttg gctaatcgtg
    30601 gcaaatttaa ggggctgatt gagacaggca cgcgcaatgc ttttggagat tcaacctgct
    30661 ttgattatgt caagtccctt ggcattacgc atattcagct ccagccggtc tttgaccatc
    30721 atcaattctt tgatgaaaat ggagattatg cctataattg gggctatgac cctgaaaatt
    30781 acaatgttcc agcagccagc tttaccagta atccgcatga gccagctacc cgtatcctgg
    30841 aattaaagga ggtcattcag gcttatcatg atgcaggcat caatgtgatc atggacgtgg
    30901 tgtacaatca tacctactca tcaagagagt cagcctttca gctgacggtt ccggattatt
    30961 attaccgtat gaatcctaat ggctcctttc aaaatggctc tggctgtggc aatgaaacgg
    31021 ctagtgaaaa ggaaatgtat cgcaaataca tgcttgattc gatcctatat tggaccaatg
    31081 agtttaacat tgatggcttc aggtttgatc tgatgggctt acacgatatt gacaccatga
    31141 atcttatccg acaagagcta gataagattg acccaaggat acttgttttt ggtgagggct
    31201 gggatatggg agttggtctg gcagctgagc agaaggctaa aaaaggaaat gccagccaaa
    31261 tgcctggaat cggctttatt aatgatgatc agcgtaatgc agttaagggg gcagaggtct
    31321 atgggagctt agagaagggc tttgtatcag gtgcaccgac agaaggactt gtagccaagt
    31381 ctattttggg cagtgatgag ctggtctctt attgtacgcc tagtcaggtg atcaattatg
    31441 ttgaagctca tgacaactat aacctcaatg atttgctgtg ggttttgaat ccagaggaca
    31501 gcaagcagga tcatgtcaaa cgggttcagc tagcttcagc tatgacgatt ctcatgcaag
    31561 ggatttactt tatgcagctg ggtcaggaat ttttacgaac aaagctttac ccaacaggtc
    31621 aggataagga gctgacacag gcagaccgag aaagggcgat gaattcctac aatgcacctg
    31681 acaatgtgaa tcaggttgac tggagacagg ttagcttgga gcgcgaaacg gttgctatta
    31741 tgaaaaaact aatctatctg aaaactaaaa cagctttgtt ttcataccca tcatttgagc
    31801 aaatcagaca gcatgtttac attgagcatg ctggtgaaaa tacgggcttc attagcttta
    31861 cagtagaaga tgaaagaaag tatcgattga ttttctctag ttttagaaac cgcttgcaat
    31921 catctgctaa tcatgttata attgaaacaa atgataagcg ctttcaagat agtgagtcca
    31981 tgctagatga gctgacagcg atgatccttg acatcacaca atagcctgag tgttctcagg
    32041 ttatttttgt ttgttgtcaa ggataaaagg gctgtagtta cagttagcag agacctatta
    32101 ggaccttgct tatcatatcg cttagcgcct tgaaaaaggg tttaggagta gggaaagaag
    32161 aggtgatggg atggataatg acttagcgct ttataccttt ggcacaggtg agaattttca
    32221 catacaggat tatctaggtg ttcatcggat taacaatgac acaggcacca gctatgtctt
    32281 tagggtatgg gcgcccaatg cagaggctgt cagcttgatt ggagatttta ctgattggca
    32341 gtccaatcca cttgagatga gccgaaatga ggctggcgtg tgggaggtta ccactagctt
    32401 gccgcaggaa ggagatattt ataagtattg ggttaggcgc caaggtggtc agcttgttga
    32461 aaaaattgat ccagtggcct ttctatttga agctagacca ggaacgggtg ctattgtcaa
    32521 aacccttcca gccaaaaaat ggcgtgatag cttatggatg ggacggcgaa agcgttttgg
    32581 ctttaggcag cgtccggtta atatctatga ggttcatgcc cattcatgga aaaaagacga
    32641 aaacgcaagg ccctatgact ttagcaagct aaaagaagag ctcattccct atctcaagag
    32701 catgcactac actcatgttg agtttatgcc ggtcatggct caccccttag atatgagctg
    32761 gggctatcag ctgatgggct actttgcctt tgagtcaacc tttggaagcc cagaagcctt
    32821 tcaggatttt gttgaggcct gtcatcttaa taatattggt gttttgattg attgggtgcc
    32881 gggacatttt acacaaaatg atgacgcctt agcttatttt gacggtacag ctacctatga
    32941 atatcaggat caccatcgtg ctcataatta tggctggggg ccctaaattt tgatttgggt
    33001 aaaactcagg tacagtcctt tttgatttca agtgcccttt tttggctgga ggcttatcat
    33061 gttgacggca ttcgagtaga tgctgttagc aatatgcttt acttggatta tgatcaaggc
    33121 ccttggactc cgaatcaata cggtggcaac caaaaccttg aggggatagc ctttcttcaa
    33181 aaattaacca cagttatcaa ggaaaaacac cctgatgtga tgatgattgc agaggaggcg
    33241 acctcagcta ccccaataac cagccctgtt gcagaagggg gactaggctt tgattataag
    33301 tggaatatgg gctggatgaa tgatattctt aggttttacg aagaggatcc ttattaccga
    33361 aaatacgatt tcaatctctt gacctttagc tttatgtatt gctttaagga gcattacatt
    33421 ttaccctttt ctcacgatga ggttgttcat ggcaaaaaaa gcctcatgca taaaatgtgg
    33481 ggggaccgct acaatcaatt tgcaggccta agaaatcttt acacctatca aatctgccac
    33541 ccaggcaaga agctgctttt tatgggatct gagtttggac agtttttgga atggaaatac
    33601 gatcatcaat tagagtggca aaatttagag gacgagctca atgccaaaat gcagcatttc
    33661 acagccagcc taaatcagct atataaggac catagcatgc tgtggcaaaa tgatgaaacc
    33721 tatgacggca ttgatattat tgatgcagac aataaggacg aatcagtctt gtcgttttgt
    33781 cgtcaaaaca ataaaggaga gctcctgctt tgtgtcttta acatgacacc tgttgaaaga
    33841 ccaggcttta ccataggtgt gccgatagca ggtctttatc aagaaatttt caatacagag
    33901 cttgaggcct ttggaggtgt ctggaaggag cacaatccct taaccaacac agtagccaag
    33961 aaatggaaga cttatccgca gaccttgagc tttaccctgc ctgcactagg agcaagcatc
    34021 tggaaaatca agcgtcgtca gaagcaataa gctattcatt gcttacttag ctgtttcaac
    34081 caaaagaagt cactacagtc atgaaaggat aacgaaatga agaatggaat gttagccctc
    34141 atattagcag ggggacaagg aactcgctta ggaaaattga cacagagcat tgcaaagcct
    34201 gctgtgcaat ttggaggtcg gtatcgtatc attgattttg ccctatccaa ttgtgctaac
    34261 tcagggattc ataatgtggg ggttatcacc cagtaccagc ctcttgcctt aaataatcat
    34321 attggcaatg gttcgtcatg gggcttagat ggtattaatt ctggcgctac gattttacag
    34381 ccctactctg caacagaggg aaatcgctgg tttcaaggaa ctagccatgc tatctatcaa
    34441 aatattgatt atattgatag cattaaccct gaatatgtgc tgatcctgtc tggtgatcat
    34501 atttacaaaa tggactatga tgacatgctt cagacgcata aggctaatat ggctagcttg
    34561 actgttgctg tgattgatgt tcctctaaag gaagccagtc gatttggcat tatgaacaca
    34621 gataccaatg accgcattgt cgaatttgaa gaaaagcctg ccaatccaaa atcaaccaag
    34681 gcttcaatgg gtatttatat ctttaattgg cagcgccttc ggaccatgct ggttgacgca
    34741 gaaaaaaaca acattgatat gtctgacttt ggtcagcatg tgattccgtc ttaccttgag
    34801 tctggcgagc gtgtctacac ctataacttt aaaggctact ggaaggacgt cggaacgatt
    34861 gagtctctct gggaagccaa tatggaatac atcggtgagg aaaatgccct agacagtcgt
    34921 gatcgttctt ggaagattta ttctaaaaac catatcgctc caccaaactt tatcacagag
    34981 gacgccgagg tcaaggattc tctggtagta gatggcagct ttatctctgg taaggtcaac
    35041 cattctatct tgtctaccaa tgtgcaggta agaaagggag ccgaggttaa ggattccttt
    35101 atcatgagcg atgttatcat tggtgagggt gcaaggatta cacgagctat tattggtgag
    35161 ggtgcagtca ttggtgatca tgtgatcatt gatggcagca aggacgttca agtcgtaggc
    35221 tataatgaag tagtgggggt accaaatgaa gattgataaa tattctgcca ttctaggcag
    35281 ctcaattggc tttgctgaaa tgaaggggct aacagacaca agaccattag ccaacctacc
    35341 ctttgatggg aaataccggc tcattgattt tcaattgtcc aaccttgcca atgcaggtgt
    35401 ccgtagcatc tatggtattt ttcgtgggca aaatatccgc tcagtgtttg atcatatcag
    35461 gtcaggtcgt gaatgggggc ttaattcctt actaagtcat tatttccttg gcttttataa
    35521 caccaaggag gattctaaag aggctgacaa ggactattat cagcagattt tgacctattt
    35581 aaagcgctca gggtcagatc agaccattta catgagctgt gatattctct gcaatattga
    35641 gcttgggcag gttattcatc tgcacaatgc caaccatcgc aacattacgg ttgtctacaa
    35701 gaaaatgccg accaaggcca tctctaaggc taacgatatt ttagatattg acgagacaga
    35761 tactgttgtt gacaggcgaa gtctgtctga ggggcaggag gttgaaaaaa tgtcagcagg
    35821 catttacatc gtcaataccc catggttaat tgaacagatg gaaaaagaag ccgaaaaaga
    35881 aaaccctcaa aagctacgct tcctcttacg tgatttgatt gtgtcagagg gcgctcttgg
    35941 ctttgaatat actggctatc ttgccaatat tcactctgtt aaatcttatt ttgatgccaa
    36001 tatggacatg ctggatccgc ataagtttta ttcactatta tatgctaatc agaaggtcta
    36061 cacgcgtgtc aaaaatgaag agtcaaccta ttttgatgcg gcttctgagg tgaacaatgc
    36121 ccaatttgct tcaggaagca ttgtcaaggg ctatgtcgag cactcaattg tctctcgcaa
    36181 ttgtcgcatt acctcacagg cacgtgttac aaatagtatt ttattgccaa aggcagtgat
    36241 tggtgagggt gctgtcattg attatgctat cattgataaa tccgtaaggg ttgcaccagg
    36301 tgttactatt agaggaagcg ctgaggagcc aatagttgtt gccaagggga ctgaggttgt
    36361 tgaggatatg ataaaatgaa gataatgttt gttgcagcag agggagctcc ctttgctaag
    36421 acaggtggcc taggcgatgt cattggggca ttgcctaaat cacttgttaa aaatggtcat
    36481 gaggtgtctg tgatactgcc ttattatgac gtggttgatc aagcctttgg tcagcaggtt
    36541 gaggacgtct tgtattttta tacgcaggtt ggctggagac gccaatacgt gggcattaaa
    36601 aagcttgtca aggataaggt gaccttttac tttattgaca atcaaggtta tttctttaga
    36661 ggcaggatct atggtgattg ggacgacggt gagcgctttg cctatttcca gctggctgcc
    36721 atagaagcaa tggagaaaat cggggttatt ccagatattt tgcatgtgca tgattaccat
    36781 accgctatga ttcctttcct attgaaagaa aaataccatt ggattcaggc ctatcaagcg
    36841 attcggacag tttttaccat tcataatatc gcatttcaag ggcagtttga tcctggcatg
    36901 ctaggcgatt tgtttgatgt tggtatagag cgctacgagg atggcaccct gcgttggcat
    36961 gattgcttga attggatgaa agcagcagtc ctatatgcag atcgggtaac cactgtctca
    37021 ccctcttatg cgcatgaaat tcagacacca gcctttggac aaggcttgga tcaagtcatg
    37081 cgaatggagg caggcaagct atcaggcatt gtgaatggta ttgacactga cttatttaac
    37141 ccagcaaggg atcctcattt gcctgcttca ttttcagcag aagacctatc aggcaaggcg
    37201 gctactaaac aggccttgca ggagcggtta ggattaccag tcagggcaga tgttccattg
    37261 attggtatgg tttcgcgctt gacggatcaa aagggctttc agcttgttct tgaggaatta
    37321 ccgcatatct tgcagcagga cgttcagctt gtcttgttag gaacaggtga ccctgattat
    37381 gaggctgcct tttcatggtt tgccaaggcc tatccagaaa aactgtctgc taatattacc
    37441 tttgatctgc cattagctca gcagatttat ggggcctgtg atctcttttt aatgccaagt
    37501 gcttttgagc cctgcggact ttcgcaaatg atggctatga gatatggcgc gataccgatt
    37561 gtccatgaga tcggcggctt gaaggatact gttgcctcct acaatgctta tgaaaagact
    37621 ggaactggtt ttggctttga tcagttttca ggattttggt taacgcagac gctcttgttt
    37681 gcccttgata tttaccataa ccacaaggag gattggcaga ctattcaaca acatgccatg
    37741 accaaggatt tttcatggga tacagccagt ctggcctacc ttgatttata taaaagctta
    37801 ctataacaca gaaaaggaat gggaatgcac gtcacaaaag aacaatttat tcgagatttt
    37861 aaagatacct tacatgagga acaattgatc aaggttcctg ccgcaacagc tgctgagctt
    37921 ttcacctcat tagcaaagct tatccgtaaa tactatacag atacttggat tgaaaggaat
    37981 cgttccttaa ccgaacagca gcaaaaaatt gcctattatt tttcgatcga atttttacca
    38041 ggaagaatgc tagaaacaaa tcttcttaat ttaggcattc ttgatacagt taaagaagcc
    38101 tttgctgact tgggaattga ttttcaagca gtgaagcatg cagagcacga catggctcta
    38161 ggcaatggag gtctaggacg tttggcagct gcctttatgg attcgctagc gacaacaggc
    38221 tatccaggct ttggaaatgg gctgcgttat cgttatgggc tgtttaagca acggattgtg
    38281 aatggttatc aggtagaatt accagattct tggtttggct ctattggtaa tgtctgggag
    38341 atcagaaagg atcatgacat tgtagacgtc aagctctttg ggaatgttta cctaaaagcc
    38401 aatcaggacg gtaagctagc gccaatctat gagggagctc aggttttgag agctgttccc
    38461 tacgatgttc ctcagattgg ctttgaaaat gatgtgatta acaatcttcg cctctgggac
    38521 gtagaaatcc cagaagaaca tgagcttgat tacccaacca tcgagtcaag acgggcagtc
    38581 aaggacatta ctgccatttt gtacccagac gacagcagct atgaaggcaa aaagcttaga
    38641 ttgatccaag aatatttcat gaccagcgca ggcatccaaa ccattatcaa atcctattta
    38701 aagcagggct tgccacttac tgagcttcat caaaaggtat ctgttcatat caatgatacc
    38761 cacccagcag tagctccagc agagcttatg cggctcttga ttgacgacta tggcttagaa
    38821 tgggtagacg cctgggcgac aaccgtaaaa accatgagct ataccaatca tacgattttg
    38881 tcagaagcct tagaaaaatg ggacgcagag ctctttaaga ctgtgctgcc ccgcgtttat
    38941 caaatcattt tagagattga tcatcgcttt gttgctgaaa tggcgcaaaa gggtattgat
    39001 cctcagatca ttgaaaacac tagaatcgtt aaggacaacc agatttatat ggctaatctt
    39061 gccattattg gtggctattc ggtcaatggc gttgccaagc tacatacaga gttgttaaag
    39121 acagataccc ttaaggactt ttatgccttg tatcctgaaa aattcaacaa caaaaccaat
    39181 ggtatcgtgc aaagacgttg gacacagatt gctgcgccag agctatcagc agctattgac
    39241 cgcacgattg gcaaaggctg gcgcaaggat attcaccagc ttcgacaatt gagtcaattt
    39301 acagaagatc cagctgtgct aaatgatttt tatcaggtaa aacaagcagc taagcagcgc
    39361 ctagccaggt atatcctgga aaaaacaggt cttgaggttt caacagaggc tatttttgat
    39421 gtgcaggtca aacgcctaca tgcctacaag cggcagctcc tgaacgtcct gcatattatg
    39481 aagctttacc ttgatttgaa ggctaatcca gatttagata tggtgcctag agtctttatt
    39541 ttcggcgcaa aggctgcacc aggctatcat tttgccaagt cggtgatcaa aatcatcaat
    39601 gagctggcta atctcattaa ccatgatacc agtctcaaag gaaagctaaa ggttgttttt
    39661 cttgaaaatt ataacgtgag tctagcagag ctcattatcc ctgcggcaga tatttcagag
    39721 cagatttcac tggcctccaa ggaagcctca ggaacatcaa acatgaaatt tatgatgact
    39781 ggtgctatca ccctagcgac ccttgatggg gcaaacattg aaatcaaaga cgaggtcgga
    39841 gaggaaaaca ttgtgatctt tggtatggat aaggatcagg tctatgacca ctatgccaag
    39901 catgattatt attcaagagg cctatatgag agcgaccctc agattaaagc agtagtcgac
    39961 gcttttgtca atggcaccat tccaaatagt caacacgaag gtatggaaat ctatgatgcc
    40021 ctaatcacgc ataatgatga atacttcttg ctagaagact tttcttccta tgtaaaagca
    40081 caggctaaga ttgatcggct ctaccgccaa aaggatagat ggtcaaaaat gtcgctcatc
    40141 aacattgccc attctgacaa gtttacatca gatgatacca tcacccagta tgccaaggac
    40201 atttggcagc taaaacgcta atccatcaag gaagaaaaag cattagttac cttagattga
    40261 agagagtgtc ttttgagacc attttcttca atcttttttg attgcaaaag accttgggaa
    40321 tcagatcagc tgcctgccta atactttggc ctatcaaggt attttggaat ttgttaatct
    40381 ttttgttata atagtggtgt gaagctattt tttaaatgaa aaagccaaca cttcaagatg
    40441 gtgttaaagt aaggttagta ttagtctaag aaagcgtaac cacattaaag aaagctgttg
    40501 acattctcaa ttttaaggaa tagaataaca aagtaaaaaa tttttaaaag gagtattcta
    40561 ttatgaatcc tattttcgca ttggctcttg cctgctttgg tgtatcactt gccgaaggct
    40621 ttttgatggc taatctcttt aaatcagcgt cacgccaacc agaaattatc ggtcaattac
    40681 gttccttgat gatcctaggt gttgccttta ttgaaggtac cttcttcgtt acccttgtta
    40741 tggccttcat tctaaaataa cagcctattt gatatagaaa aggagggtat taaatggaag
    40801 aagctaaagt accgatggta gagcttggtc caataacctt taatttgacc ctacttgctg
    40861 tttgtattgt tactatccta ctgatatttg gctttgtttt ttgggcaagt cgtcagatga
    40921 cattaaaacc aaaaggcaag caaactgcgt tagaatattt aatcagcttt gttaatggta
    40981 ttggggaaga gcatttggat agtcatcttc agaagtctta ttcgctttta ctttttacca
    41041 tttttctttt tgtggcagtt gccaacaact tgggcttatt tacaaagcta gaaacaacca
    41101 gtggctacaa cctatggaca tcgccaacag ctaatttggc ctttgaccta gccctatctc
    41161 tgtttgtgac gcttcttgtt catatcgaag gcattagacg tcgtggtttt ggcgcttatt
    41221 taaaacgctt tgcgacacct tggccaatga ctccgatgaa cctattagaa gaatttacca
    41281 acttcctatc acttgctatc aggctgtttg gtaatatctt tgcaggagag gttgtgacag
    41341 gcttgattgt tcagctggcc aattatcgcc tgtattggtg gccaattgct ttccttgtta
    41401 atatagcatg gacagccttt tccatattta tttcctgcat acaagccttt gtatttacaa
    41461 aattaacagc aacgtattta ggaaaaaaag ttaatgaatc agaagaataa gaagggagga
    41521 caaacgaatg tcagttacaa ttggtgagct cattgggaat tttattctgg taacaggctc
    41581 tgtcatcgtc ttgttgctct tgattaaagc ctttgcttgg ggtgctatcg aagctgtttt
    41641 acaggcacgc tcacagcaaa tttcacagga tattgaccaa gcagagcagg cgcgtctcaa
    41701 cgcccagcag cttgaaaagg aaggtcaagc caatctagaa gccagcagat cagaggctag
    41761 tcagattgtt gaggcagcca aagaaactgg taaagcacag gagacacgca ttgtagcaga
    41821 ggctacagaa gaggcagatc gcctaaaagc agcagcgttg acagatatcg aacacagcaa
    41881 gtcagaggct atttcagccg ttaagacaga aatgtcagat ttgacagttt tactagcaga
    41941 aaaaattatg ggagccaatc ttgataaggc ggctcaaagc cagcttattg atcgctatct
    42001 tgatgattta ggagaggctt aatgaccaaa aaagaacaag ctcttatcga gcaatatgca
    42061 aaaagtcttg tgcaggtctg tcaggagcga gacactcttg aagcactgca ggctgatgtg
    42121 cttgccattt tagaggtttt taaagctact aatcttgcta agacattgtc aagcttagcg
    42181 gttccacgtg ctaaaaggct tgagctagta aggcagcttc aaggagataa tatcgtttat
    42241 ctgaataact tgctagaagt tatgctgcaa aatgagcgtg aagcttattt atatcaagtg
    42301 cttctaaggg ttttatccga gctggctagt gtctcaaatc aatatgacgt gacagttaca
    42361 tcagcagttc ctttaagtga ggagcaaaag cagcgtgtgc gtacagtggt ttcaaagaga
    42421 cttgcagtaa agacaggtcg cttaatcgaa aaggtagatc cttctttaat tggaggattt
    42481 atgattagcg tcaataataa ggtaattgat acaagcattc gtcgtcaatt acaagcattt
    42541 aaaatgaatt taaaatagaa agtggtgtga cttttggcaa ttaatgcaca agaaattagc
    42601 gctttaatta aaaagcaaat tgagaacttc cagccaaatt tcgatgtcac agaaactgga
    42661 gttgttacct atattggtga tgggattgca cgtgctcgtg gcttagacaa tgcgatgagt
    42721 ggcgagcttc ttgaattttc aaatggtacc ttcggtatgg ctcaaaacct agagtcaaac
    42781 gatgttggta tcattattct tggtgatttt tcaacgattc gtgagggtga tgaagtcaaa
    42841 cgtaccggta aaattatgga agtgccagtc ggtgaagctc tcattggacg tgtggtcaat
    42901 ccacttggtc agcctgttga tggcttaggt gacattgaga caactggctt taggcctgtt
    42961 gaaactccag ctcctggtgt tatgcagcgt aagtctgttt ttgagtcctt acaaaccggt
    43021 ctaaaggcta ttgatgcttt ggttccgatc ggtcgtggcc agcgcgagct gattatcggt
    43081 gaccgtcaga caggtaagac gtctgtagcc attgatgcca tcttgaatca aaaggggcag
    43141 gacatgattt gtatctatgt cgctattggt caaaaggaat caacagttcg gacacaggtt
    43201 gaaaccctac gtcgttatgg tgctttggat tataccattg ttgtaacggc ttctgcttca
    43261 cagccatcac ccttgctgtt tattgcacct tatgctggtg ttgcgatggc agaagagttt
    43321 atgtacaatg gcaagcacgt tttgattgtt tatgatgacc tgtctaagca ggcggtagct
    43381 tatcgtgaat tgtcgctctt gcttcgtcgc ccaccaggtc gtgaggccta tccaggagat
    43441 gttttctacc tgcatagccg cttgcttgag cgctcagcta aggtgtctga tgacttaggt
    43501 ggtggctcaa ttacagcctt accatttatt gagacgcagg ctggggatat ctctgcctac
    43561 attgcgacaa acgtgatttc gattacagat ggtcagattt tcttgcaaga ggatctcttt
    43621 aactcaggaa tccgcccagc tattgatgct ggctcgtcag tatctcgtgt cggtggctct
    43681 gcacagatca aggctatgaa aagggttgca gggactttgc gtcttgacct agcctcttat
    43741 cgtgagttag aagcctttac acaatttggc tcagatctag atgcagcaac gcaagcaaaa
    43801 ttaaatcgtg gtcgtcgtac tgttgaaatc ctaaagcagc cactgcacaa gcccttgcct
    43861 gttgaaaagc aggtggtcat tttgtacgct ttgacgcatg gatttttaga tgatgttcct
    43921 gtagatgata ttttagcctt tgaagaagca ctttatgact actttgatgc gcattatgat
    43981 cacttatttg aaacaatccg tacaaccaaa gaccttccgc aggaggctga gctggacgtt
    44041 gctattcagg ccttcaaagc acagtcaaac tttaaataaa agaggggggt actagtatgg
    44101 caggctctct aagtgaaatt aaggctaaaa tcatttcaac cgaaaaaaca agcaaaatca
    44161 ctagcgccat gcgtatggtt tcttctgcaa agcttgttaa atctgagcaa gcagctcgtg
    44221 attttcaaat ctatgcttca aagattcgtc agattacaac agacttactg aaatcagacc
    44281 tgacaacagg ctcagataat cccatgctgg tgtctcgtcc tgtgaaaaag acaggctata
    44341 ttgttattac ctctgataaa ggactggtcg gtggttacaa ttcaaaaatc ttaaagtcca
    44401 ttatggacat gattcaggaa taccatgccg ctggcgatta tgagattatc tcaattggca
    44461 gcatcggctc agattttttt aaggccagag gtatgaatgt tgcctttgag ctgcgcggcc
    44521 tagcagatca gccaagcttt gatcaggtcg gaaggattat ctctcagtct gtaggtatgt
    44581 ttgtcaatga gatttttgat gagctgtacg tctgctacaa tcaccatgtc aatagcttga
    44641 cgagccaggt tcgggttcag cgcatgctgc cgatttctga tttggttgcc gaggaggccg
    44701 cagaagaagg tgtcactgga tttgaattag agccaaaccg tcatgtgatt ttggagcagc
    44761 tgctgccgca atttactgaa agcttaattt atggtgcgat tattgatgca aaaacagcag
    44821 agcatgctgc tggcatgact gcaatgcaga ctgccactga caatgccaag catgtgatca
    44881 atgatttgac catccagtac aatcgtgcgc gtcaggcggc cattacacaa gaaattacag
    44941 aaattgtagc tggtgctaat gcacttgaat aagcttattg tatgctgata gcgctctagc
    45001 agagacctat tagcacttaa tgtcatcttc aaagctagat gacatttggg attaatgagc
    45061 taggggcctt ttacccttag ctactcgaat ttagaaaaat tcagcttaat cccctactat
    45121 cgaatataag gagaaaaaca tgagctcagg caaaattgct caggttgttg gtccagttgt
    45181 agacgttgtg tttgcgagtg gggacaaact accagagatt aataatgcgt tgatagttta
    45241 taaagatggc gataaaaagc aaaaaatcgt tctcgaggtt gccctagagc ttggagacgg
    45301 tatggtacgt acaattgcta tggaatcaac cgatgggctt acacgtggat tagaggttct
    45361 tgatactggt cgtgccatta gtgtaccagt tggtaaagag actctaggtc gtgttttcaa
    45421 cgttcttggt gaaaccatcg acctagaagc accatttgca gatgatgtta atcgtgaacc
    45481 gatccataaa aaagcaccag cctttgatga attgtcaaca tcatcagaaa ttcttgaaac
    45541 aggtatcaag gttattgacc tgcttgcccc ttacttaaag ggtggtaagg tcggtctttt
    45601 cggtggtgcc ggagttggta aaaccgttct tatccaagaa ttaatccaca atatcgctca
    45661 agagcatggt gggatctcgg tatttaccgg tgttggtgag cgtacgcgtg aaggaaatga
    45721 cctttactgg gaaatgaagg aatcaggcgt tattgaaaaa acagccatgg tttttggtca
    45781 gatgaatgaa ccaccaggag cccgtatgcg tgttgccttg accggcttga caattgctga
    45841 atatttccgc gatgttgaag gccaagacgt cctgctcttc attgacaata ttttccgctt
    45901 tactcaagca ggctcagagg tatcagccct tctaggtcgt atgccttcag ccgttggtta
    45961 ccagccaaca cttgccactg aaatgggaca attgcaagag cgtatcacct caacgaaaaa
    46021 aggctctgtt acctctatcc aagccatcta cgtgccagct gatgactaca ctgatccggc
    46081 gccggcaaca gcatttgctc acttggattc tacaactaac cttgagcgta agctgacgca
    46141 gatggggatt tacccagcgg ttgatccact ggcttcaagt tcacgcgcgc tgtcaccaga
    46201 aattgttggt gaggagcact atgcagtagc cacagaggtt cagcgtgtct tgcagcgcta
    46261 tcgtgaattg caggatatca ttgctatctt aggtatggac gagctgtcag aagaggaaaa
    46321 gacattggta ggacgtgcgc gtcggattca gttcttctta tcgcaaaact ttaacgtcgc
    46381 agaacagttt acaggccttc ctggctctta tgttccagtt gccgaaaccg ttcgtggctt
    46441 caaggaaatc ctagaaggaa agcatgacca ccttccagaa gacgcctttc gtgctgttgg
    46501 accaattgag gacgtgatcg aaaaagctaa gaaaatgggc ttttagtgag gtgatgccat
    46561 gacacaaatg actgttcagg tggttacgcc agatgggatc aaatatgatc atcatgctaa
    46621 gttcatctca gtaacgacac cagatggtga gatggggatc ttacctaacc acatcaatgt
    46681 gattgctcct ttacaggtgc atgaaatgaa gattcgtcgt gtcagtgaag acgatcgcgt
    46741 tgattgggtt gctatcaatg gtgggatcat tgagatcaaa gacaacgtgg ttaccattgt
    46801 tgcagattca gccgaacgtg atcgtgatat tgatgttagc cgagcagagc gggcaaaatt
    46861 gcgagcagag cgtgacattg cagaggctga aaccactcat gatattgatg aggtgcggcg
    46921 tgctaaggtt gctttgcgac gtgccttgaa ccgcatcaat gttagtaaaa aatagtaaaa
    46981 tgagtctaac ctaccaattt aaccaagaca gagcgagtag cgctgcttag gaaagggtgt
    47041 agatagactc ttttatcttt ttatagaaaa aataccctct tt
//
LOCUS       DARYMD010000012        44977 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYMD010000012 DARYMD010000000
VERSION     DARYMD010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44977
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(80..1285)
                     /locus_tag="TU818_000593"
     CDS             complement(80..1285)
                     /locus_tag="TU818_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL0923439.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLADVIDKV
                     YTRDVFGRD"
     gene            complement(1538..2791)
                     /locus_tag="TU818_000594"
     CDS             complement(1538..2791)
                     /locus_tag="TU818_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL0923440.1"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(3188..3808)
                     /locus_tag="TU818_000595"
     CDS             complement(3188..3808)
                     /locus_tag="TU818_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923441.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(3849..3944)
                     /gene="ffs"
                     /locus_tag="TU818_000596"
     ncRNA           complement(3849..3944)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TU818_000596"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            4121..5347
                     /locus_tag="TU818_000597"
     CDS             4121..5347
                     /locus_tag="TU818_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL0923442.1"
                     /translation="MKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLSQAEKENYLLLYDSLSAFHEVTSLAPASKHSLMTTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDVFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISISIINQQ"
     gene            complement(5457..5951)
                     /locus_tag="TU818_000598"
     CDS             complement(5457..5951)
                     /locus_tag="TU818_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL0923443.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEVGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKI"
     gene            complement(5948..6730)
                     /locus_tag="TU818_000599"
     CDS             complement(5948..6730)
                     /locus_tag="TU818_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL0923444.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDRVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHMPPLP
                     PEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLGSLSQ"
     gene            complement(6829..7368)
                     /locus_tag="TU818_000600"
     CDS             complement(6829..7368)
                     /locus_tag="TU818_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL0923445.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(7372..7683)
                     /locus_tag="TU818_000601"
     CDS             complement(7372..7683)
                     /locus_tag="TU818_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923446.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPAYHKHQDIYFSKE
                     L"
     gene            complement(8070..8207)
                     /locus_tag="TU818_000602"
     CDS             complement(8070..8207)
                     /locus_tag="TU818_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0923447.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     gene            complement(8591..9835)
                     /locus_tag="TU818_000603"
     CDS             complement(8591..9835)
                     /locus_tag="TU818_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0923448.1"
                     /translation="MRNKKTSIRLVQKYGICSAVVALATIASLGIGNDVRAEDFTYPS
                     MYNQGYFFQQFIKKEILNPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPAGPQGLRGERGPVGERGPIGPQGPEGKPGQQGP
                     KGDTGPQGEPGQQGPKGDIGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEQGLQ
                     GPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKGDTGPQGAPG
                     QQGPKGDTGPQGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPK
                     EPETPKAPEQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPF
                     FTLAALSVIASAGVLGLKKKQD"
     gene            complement(10264..11406)
                     /gene="tgt"
                     /locus_tag="TU818_000604"
     CDS             complement(10264..11406)
                     /gene="tgt"
                     /locus_tag="TU818_000604"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL0923449.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVSMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            11811..12656
                     /locus_tag="TU818_000605"
     CDS             11811..12656
                     /locus_tag="TU818_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL0923450.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLIYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(12852..16814)
                     /locus_tag="TU818_000606"
     CDS             complement(12852..16814)
                     /locus_tag="TU818_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL0923451.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VTASAAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSKSQ
                     VAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVNPSKVGHGSFL
                     QDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYSRR
                     GKDDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKNNG
                     NDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVLER
                     EFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNALGD
                     LYATNKADLEDKGNGYVYKKMMLATAVAYCKEIKSFVVNYGGTYLASDPVLKYQAFKE
                     LYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGYSY
                     TKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAVCW
                     GLSNLGVAVNEVFGIPAVNIYQNDHEAYLVYRQDDQGNGIWDIRDNVYGNRWAISYSR
                     WGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVYEA
                     GSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYPQV
                     MVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTGNP
                     IETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNIED
                     GILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEHLEVSLDNGQSWQAYD
                     GTERFNDTVTVLARYRAHGTSLASDSVTYTFTADSTDPTMHYISIDDIQAVTYANEQS
                     GRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHSAK
                     VDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKFVS
                     GSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFAITNSGLTAATT
                     EKNQAIQGKILETIKDLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPLYV
                     LAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAVNT
                     ALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTAYALDRGAFQQL
                     "
     gene            complement(16949..18775)
                     /locus_tag="TU818_000607"
     CDS             complement(16949..18775)
                     /locus_tag="TU818_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL0923452.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHLNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASPTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSNKTELRKSLEEAKLKLSQPEGTYSDESLQALQSAVTIGKTYLNS
                     DPDQNTVDQSVTTIDSAITSLVNLNALNEAINQATPFITDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SESLKELYNKAIEAAGTFYRTVNKDKERKDISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVDPVDPVDPVDPIDPADPVKPSDPEVKPEPKPESKPEAKKEDKKA
                     ADKQQVLPATADTANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            complement(19135..19608)
                     /gene="perR"
                     /locus_tag="TU818_000608"
     CDS             complement(19135..19608)
                     /gene="perR"
                     /locus_tag="TU818_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL0923453.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQTKQGKDTDY"
     gene            complement(19645..20097)
                     /locus_tag="TU818_000609"
     CDS             complement(19645..20097)
                     /locus_tag="TU818_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL0923454.1"
                     /translation="MIDTFQNPSDETITSYLESSKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFKVDIANVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            complement(20337..22979)
                     /gene="polA"
                     /locus_tag="TU818_000610"
     CDS             complement(20337..22979)
                     /gene="polA"
                     /locus_tag="TU818_000610"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL0923455.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYEHIDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPA
                     ASYDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETM
                     ESAVSLAVPLRVDESAGKSWYEAK"
     gene            complement(23403..25133)
                     /locus_tag="TU818_000611"
     CDS             complement(23403..25133)
                     /locus_tag="TU818_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL0923456.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKNKIVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLALRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTMMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMLSSSADKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQKA
                     YSNLADWELVAASTGAMTTSLDQAVKKKEPIVVTAWSPHWMFAKYDLKYLADPKKTFG
                     SKENINTIARRGLKADLPAVHRIVDHFHWEKEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(25151..26347)
                     /locus_tag="TU818_000612"
     CDS             complement(25151..26347)
                     /locus_tag="TU818_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL0923457.1"
                     /translation="MGTILEVRHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKLSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            complement(26547..26789)
                     /locus_tag="TU818_000613"
     CDS             complement(26547..26789)
                     /locus_tag="TU818_000613"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923458.1"
                     /translation="MTSSYGQSKLTLCLADLIAIGSLLGSLSIGLVAGQESDRSIKSA
                     RGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            complement(26854..27945)
                     /gene="ulaG"
                     /locus_tag="TU818_000614"
     CDS             complement(26854..27945)
                     /gene="ulaG"
                     /locus_tag="TU818_000614"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL0923459.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(28140..29786)
                     /locus_tag="TU818_000615"
     CDS             complement(28140..29786)
                     /locus_tag="TU818_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL0923460.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVADYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKRDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMIAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADWDKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPVLIVNPILSDDDIIRLIRFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            complement(30090..30806)
                     /locus_tag="TU818_000616"
     CDS             complement(30090..30806)
                     /locus_tag="TU818_000616"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL0923461.1"
                     /translation="MAKRLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            complement(30806..31669)
                     /locus_tag="TU818_000617"
     CDS             complement(30806..31669)
                     /locus_tag="TU818_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL0923462.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKVLGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEAMFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLS"
     gene            complement(31674..32339)
                     /locus_tag="TU818_000618"
     CDS             complement(31674..32339)
                     /locus_tag="TU818_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL0923463.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGERGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVNVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            complement(32434..32919)
                     /locus_tag="TU818_000619"
     CDS             complement(32434..32919)
                     /locus_tag="TU818_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL0923464.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLTKPVTFSDGKEASVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLVACHTPAEVLALVDESKNSPYLEGLDLD
                     S"
     gene            complement(33135..33413)
                     /locus_tag="TU818_000620"
     CDS             complement(33135..33413)
                     /locus_tag="TU818_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0923465.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            complement(33528..34961)
                     /locus_tag="TU818_000621"
     CDS             complement(33528..34961)
                     /locus_tag="TU818_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0923466.1"
                     /translation="MKMLIAPLNWFSQDILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGS
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLASFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFARAKDKEAYYRGEAQ"
     gene            complement(35444..36064)
                     /locus_tag="TU818_000622"
                     /pseudo
     CDS             complement(35444..36064)
                     /locus_tag="TU818_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(36066..36683)
                     /locus_tag="TU818_000623"
     CDS             complement(36066..36683)
                     /locus_tag="TU818_000623"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923467.1"
                     /translation="MKLSNLLVVGMKACLTGLLIHLLLIKANMTGERDFHNLVCYRLL
                     MPFPVIEGETADFVKVITLLGLSFNSFYFTISFLADLAEGTKEIFRFHARSQLVFFNK
                     LWRTSTIFYIKEWLLFIVLILGVLMTYYGAPYHIERLCYLMVSWLTIDICLIYVMIRY
                     ASSAVVAMILFASLTLIRYFLFDVWWCLLLIVLVHMLYDNYYKES"
     gene            complement(36670..37458)
                     /locus_tag="TU818_000624"
     CDS             complement(36670..37458)
                     /locus_tag="TU818_000624"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923468.1"
                     /translation="MLQYRLFPFRYFYPLVPLLFLGFIYFDSLKHILFFDTSAVDLSG
                     GIEVKKSLLLSMIRLDSVVFDFSFYQSFIYPLVMILVAYAYYYLKSRHLKYLIGRKSD
                     YGKRCIFLKLQLSLYVLLSFYIVIFALTLVSWLNGVAHMNGNLMPYFDQNSILRFFGQ
                     GATTFIAYYCLVKSLALFVHTYFVCFLVDYLQSFIKSSMLYLILMWALSPLLYSYLPP
                     KYVLMTSLMSTSYSDADIPYLLSPYLGLVGVCIVLKLRKHHEII"
     gene            complement(37529..37930)
                     /locus_tag="TU818_000625"
     CDS             complement(37529..37930)
                     /locus_tag="TU818_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923469.1"
                     /translation="MKLGKIKIGLLAIVASTLLISSLVIAERQIGYLQNFRITSSFGR
                     TKDYLVKSAAPYYVVNLDSRGRNREIVVRHYLANSNGQRRSDIDKTWTGDRGIYTQDT
                     KSGYLYALHLVRENWWDGATTISGSWSPDNW"
     gene            complement(38291..38782)
                     /locus_tag="TU818_000626"
     CDS             complement(38291..38782)
                     /locus_tag="TU818_000626"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923470.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSSRYNYTGWNQGGYSWK
                     YLRLRNKNPYSRRTLTEDYSDQRKNEAKDSIKELSKLSDKEKKNFADRIDALTDTYAI
                     SSILSEAKNKNNDYLEFDKEYEALFNSNKYKLEIEKIKDRVYFDEGYSARQGINDLKS
                     LEN"
     gene            complement(38969..41470)
                     /locus_tag="TU818_000627"
     CDS             complement(38969..41470)
                     /locus_tag="TU818_000627"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL0923471.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            complement(42059..42922)
                     /locus_tag="TU818_000628"
                     /pseudo
     CDS             complement(42059..42922)
                     /locus_tag="TU818_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(43204..44721)
                     /locus_tag="TU818_000629"
     CDS             complement(43204..44721)
                     /locus_tag="TU818_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0923472.1"
                     /translation="MSIENLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLIEVKIDFAIFRQLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLEK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDISE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
BASE COUNT        12966 a        10457 c         8664 g        12890 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccactt gttttctgac tagtctcttc caaagacatc tctcgtgtaa accttgtcaa
      121 tgacatctgc taggtcgtcc tcaaagcgat ttgacacaat gattgtagac tcgtttttga
      181 actgctctaa atcctttaca actctatagc caatgtcctc accaagcatg ggttcgtaaa
      241 tgacaatatt aaccccatag tcgttgatga tatcaataat atctttaatg gcgctttctc
      301 ggaaattatc agagttgctt ttcataatca agcggtaaaa gccaatcgtt aatggtacac
      361 cagcctgctt ttgactagag gctctgtcta atatttgttc agccaaataa gattttcgta
      421 tcttgttgga ttcaacaatc gctgacatca aggactgggg aatgcctcta taatttgcca
      481 acagctgctt gctgtccttt ggcaggcaat agccgccata tccaaaggaa gggttattgt
      541 aatggttacc aatgcgctga tcatgacaga ctccttcaat cacgcgctga gcatctagac
      601 ccttgctttc ggaataggtg tctaattcat taaagtaaga cacccgcata gccaaaaagg
      661 tattcgcaaa tagcttgacc gcctcagcct cctgtgagcc cataaataag accggagtat
      721 ccttgctttt ggctccttcc tttaaaagac cagcaaaggc tttagcagcc tgaataaccc
      781 ttggtgagtc gtccttttca taagaaacaa tgattcgact tgggtaaagg ttatcgtata
      841 aggcttttga ttctcttaaa aattctgggc taaaaataat acgatctgtc tggtattttt
      901 ccctaacatg cttgataaag cctagtggta tggttgattt gataataatg gttgctgacg
      961 catttaggtc taggacctgc tcgatgacct cttcaacatg ccttgtgtca aagtagttgc
     1021 gttcgctgtc ataatttgtc ggagtagcaa tgataataag gtctgcattg ctataagcgc
     1081 ttgcgccatc aagcgtcgct gtgagattta gcggcgcatt ttttaaatac tcctcaatat
     1141 cagcatcctt gattggcgat atgccttgat tgatcaatct caccttttca tcaataatgt
     1201 caacaacagt gacgtcatta tgttgtgcca gtaaaatact caaggatagg ccgacatatc
     1261 ctgagcctgc tacagaaatt ttcacttcat tttttccttt gataccttag tacagttagc
     1321 tactgccgga gctcaggtgc cacacctgaa ggaccatgat gacctagccc tcataccaaa
     1381 gctgacgctc agcctctggt tcgtcttcac agggctacaa gctaaaagct cttaactcaa
     1441 gtacaagtgg actagcttta tttgatgagc tgcttaactc aagatgcttt gttcactcct
     1501 agcttagctc ccttgtcaga acctaggtct agttggttta taataatttt ttacgtgttc
     1561 cccagtcagc atttctaata gtaaaaagag aatacaattt caagggctgt aggacaaaca
     1621 aatgcagcac cccataaaac ggagataaca agaaggacag cgggtgctta agcatgtaat
     1681 gaatgttccg acaaagagca acaatgaaga taatcaccag aaaggctaaa accctgagcc
     1741 aatcaaattc tctgacattg cctacaaaga aatccaccac agaataaaca agcatcataa
     1801 acatagacac ctcaagtatg gtccataggg ctacaaaagg attgttcatg attttcttaa
     1861 cagaaataat ggactctcta aagaaggact tgttccagcg gttttgctgc ttcaagtaag
     1921 tagacatctt gtcaggaaca tctgtaatac atttagcagt ggattgataa acagtctttc
     1981 ctaaatcagt tgcatagttg gtcaagcacc tgtcatcacc gatacttaca ggaataccca
     2041 ggaaggtctg gttgatgtat ctgtctatat taggaacaac cacctcgcgt ctgtaaacgc
     2101 taagtgggcc tgagcaaaca aggatattac ccgtaactga ttgggcagct cgttcaacgc
     2161 caaaagcatt atcatagcga atatctgtca agcgtgttaa gagattggtt tgtctatttc
     2221 tgacattaag gtgacccgtc gcagcaaaaa cagttgggtc attaaaggtc tttaacagct
     2281 cctctaaagc atcagggtag atataagtat ctgagtcaac ggtcaaaaag acatcagcgt
     2341 ctgatctttc aaaggcccag gcctgtgcat gacgctttcc ttgatttttc tctgaccgat
     2401 gaacaatgac attgcttgat aggtcaccag tgtcacgcac atagtcttca atgcgcttaa
     2461 tacctgtctc atcagcactt ccatcgtcaa caacataaat ttctgctagg ggataggttt
     2521 gctgctgaac actttttaag gtctctagca atgactcagc gtcttcgtta taagagggaa
     2581 taatggctgc aaccttatat tgcccagccc ttcccttaaa tggcttgtaa aaaaaagata
     2641 aggacatttt gactaataga taagctatca gcaaaaagcc ataaattgac aagcttcctt
     2701 tagcaccaaa gagataaaca ttgacgtaaa tcaacagtac ccaaaaaata ctaaaggcca
     2761 caacagttat gaggtttttt aatgttctca ttgtgattgg tttgctcctc tcttgcgctt
     2821 tgtattttgc ctttaaacac taaccataat ataccatctg tcacagcaag caaacaaggt
     2881 cattaattta ccattctatt aaagatagat taatcttagt gtcaatacag ctttttctaa
     2941 gatttgccta tgctcaccaa gtcatcaatc ccctacaaaa aacaaatgat agcctgagtc
     3001 tacctgtggc tatcgctagc atgtgcctga taacaagcag ctaaatggcc cgtccaaaac
     3061 taaggcgctt tggacagccg cttttcgctc tcttttttga catcaaaaaa gcagccctta
     3121 tcaggccact tcatattggt aacaaagcaa ttctataagg agctccttaa aggataaggg
     3181 caagagatta ctttagagac ttgatgatct caatgcgagt gataaccccc tcatgcatat
     3241 gatctactct taaggcaaca tcagaaaaag caatagatgc cccaatcgtt gcagtctttc
     3301 cttcctcttc caaatggcgc agcattaaat cacgcattag ctcgtttttg ttaataaccg
     3361 gcagctcgac acgcgctagc acattagcta ttttgacctt ttgactgccc cgaacgataa
     3421 tgcttgaagt atcatcaaag cttgtaaaaa ggtattttcg cgtcgcaaat aaaatagcaa
     3481 gagctatgac actcaacaaa gaatccttag cagagccatg agcgacaaca atttgccggg
     3541 caatcgcaaa caaaagcacc tcaataatgg ttcctgaggt atgcttactc agcattttaa
     3601 tcagctcgac accaatagca atactcatgg cctggtttaa aaagctctgt aaataggtat
     3661 caatgccact ttttatggta aaaatacctg tcaagctcaa ggccaagcgc cctgtcagca
     3721 ctagtaacga aatcaccaag atgatggaaa taataatctc aacataatga gatagctcat
     3781 acaatctaat ctgcaaatat tttctcatag caactcctta tcattattat ataaaaaatg
     3841 ccactatttg aaaataaaaa aagagcacac acccgatatc gcttagggct gctggattcc
     3901 tcccctgacc cacttcacgc acaagtgttg ctccaccttt attgtagcat atattgtacc
     3961 ctaaaacaag tcttatttca aaaacgtctc acatctggct cataaagctt aattagctca
     4021 acagcaaacc aagcaaacgc tatcaataag gccagtcctt aaagctaagc ccgactagac
     4081 ttgtgctata atggtactaa caaacctgag tggagatgat atgaaaaaca agcttagcct
     4141 attcttgctg gcagcactta ctatagtcgg tctctcagcc tgtgcatgga gatccaatcc
     4201 tcttgctgac aaggagcagc agttcggcct gactggagca agacgtcagc aggtgcttga
     4261 tcagatcgat caacgttatt attaccagca gcttagtcag gcagaaaagg aaaattacct
     4321 tctcttgtat gatagcctct cagcctttca cgaggtgact agcctagcac cagcttctaa
     4381 gcatagcttg atgacaacca ttgatgcctt tatgatggat aatcctgcct ttttctggat
     4441 tacctcagcc aactaccgct tggaacgctc ggatcaggtg gccttcgtta cctttccatt
     4501 gccagagaag gtcgaacaaa catatcacag gcttcaagcc attggagatg atatcatcgc
     4561 tgacatgcca gcaaccaatg actatgagcg cgtgaggtat ttttatgagt ggatcatcaa
     4621 gcaaactgac tacaatagag atgcctttga ggcatatcaa tcgggtcatg aggccttgat
     4681 agcctctaat caagacattc gcagtgtctt tcttgatcat ctttctgtct gcaacggcta
     4741 tgcacaggcc tttcagtttc tttgccaaaa ggccggtatt cctgtcgcct atattcgagg
     4801 gtcagtcacc tttgatcgat cacaggacgt ttttactcat gcttggaata ctgttcagat
     4861 tgcaggcaag aactatgctg ttgacacaac ctttggagat cccgtctttg atcaaaacga
     4921 atccattaaa caactagagg ttaattataa ctttttatgc ttgccagacc agctcatgaa
     4981 gcagtcgcat caagccagca gggatattgt gatcaatcag acagaaacct tgaccgatgt
     5041 ctggacaatt cctgagtgct cagacgattc tctgctctat actaagctca atcacagcta
     5101 ctttactgcc tttgatagac cagacattct ggccagtctt gagcagcaat taaggactaa
     5161 tcagccacag accagcttac aatttgctaa tcaggacctc tacaaccaaa tggtaagtga
     5221 tcttgagcag cattctgaca gctaccatag cctgtttcaa gcttattggc ctaatgctgc
     5281 tggctatttc tacagtctac accccagcac ctttagcatt agcattagca ttatcaatca
     5341 gcaatagcct aataccctga cagacaagta caagcgctta tggcatggct ctaccagcca
     5401 ttaaagagct gtgctaggct ctcaagggtc ttttttcttg ctaatcgctc aatgggctaa
     5461 atcttacttt ccttatcctg ctttttctgg tcacgccttt gccggaaaaa ggtctgcatg
     5521 agcttggcac agtcatcagc taaaagacct acctcaagct gtacacgatg gttcaggcgc
     5581 tcatcggtta agatctgata aagactacca gcaccgccaa acttttgatt gctggcccca
     5641 tagaccacat gaggaattcg agctagccca atggctccgc tgcacatgac acaaggctca
     5701 atcgtcacaa aaagagtcgt atccaagaga cgccaattgc cttcgtgcgc attggcttca
     5761 ttaatggcca tgatctcagc atgcataatc gcctgattgc gctcctcgcg agcattgtga
     5821 ccacgcccga taatgtgacc agccttcaca ataacgcagc caatcggtat ctcgtccttt
     5881 agcagcgatt tctcagcctc cttgagggct tctcgcataa aatactcttg ctcttgtttg
     5941 gaatagctca ttgagataga ctccccaaat cccaagcccg atgtggcaga gcaagatcaa
     6001 caggaatctg accagcatag ccttgagctt gctgtcgcag cacctccaaa tgcctcttag
     6061 gatcaatccc ctctggcggc agaggtggca tatgggtcaa gaccaagcgt ttcaccttag
     6121 cacggctggc aagctgccca gcctcttttg aggtcaaatg cgccatatga tgttcattgc
     6181 cttcataaag gtacacatct gctaaaaaca catcagcctc cgcagcaaaa tcagccagct
     6241 cttcaaagta gcctgtgtct cctgtaaaga caagcacctg cccagttgct ctttccacaa
     6301 tacgaaaagc atagcacacg accgggtgaa ccgtcttaat aaaggtaatg tcaaaaggtc
     6361 caagagcttc aaccctatca acctgatagg caatgccctt tgagacacct ggcaaggtta
     6421 gtttggcaaa ctcggcctca tcttcgtcat gaccgtaaat aggtagtagc cttggcttgc
     6481 caagatgcct tggatagagc tgataataat gacgcaaaac acccaagtct gccacatgat
     6541 ctggatgata atggctaatg ataacagcgt ctaaatccag cggattgatt tctttttcta
     6601 attcgttaag agaacgacta ccagcatcca tcaataattg aaaaccatca tgccctgtca
     6661 caagataggc tgtcgtccca gcatcttgat agggataggc tccccaagag ccaagcgttg
     6721 ttaatttcat cacaaaacct tccttcatgc tttgttctta ttataacaaa aaatagcagc
     6781 aaaaaataag tcctagtgcg caagagctag gacttacagg cttagtattt agctgttggt
     6841 gtttaaaaag ctgtctttat agctaacagc aagcgccgtt gcgatgactg ccttaatagt
     6901 atctcccggg ataaagacaa ggctagcaac gagcgatcta gtgagcggca tgtctgtata
     6961 aaccgctagc caaatagtcc ccaacagatc caccagcagg acaccagaaa taaagattgc
     7021 taaaaaagca agagaccgat accttgctag ccagctgcgg tacaagaatg caaaaaccaa
     7081 tggaacaaag agccaggcca aaacatagcc agccgatggt cccattagga ctggaacagt
     7141 tgttctagag cctgaaaata ctggcaagaa cagaccaatc actagaaaaa gcaggataga
     7201 cagggttcct tttttcccac ctaaaatcaa gccagcaagc atgaccccta agttttgcaa
     7261 aacaatcggc actggaacaa agcctagagg aatcgctgga ataagaccta aaataatgat
     7321 taaggtggtc atcattgcta ccttcactaa gtccttggtt gacaacatat ctcataactc
     7381 ctttgaaaaa taaatatcct gatgcttatg ataggctggg ttaaaagggc taaaacaaaa
     7441 aggacagctg ccgcactcat attcggacct tctcagcagt tgtcggcaat gaccacaaat
     7501 caccggatag gtctccttgt ggtctgtcgg ctcaaaagca tgatcttgaa gcgtgtcatg
     7561 acaatgataa caggcataat aagcctgaca tcgagcacac ttcaagccga caatatccag
     7621 cactgtgtga taatgtacac agcgatactc ctgatcaagc gcgataccaa aacagttcct
     7681 catgtcttat cctcttatta aaaggataaa gcattcgttt tattttgtca acctatattt
     7741 actaataggg ttactaatca cataagaaga acaccaaaaa agcataaagt agtcccatag
     7801 gcagctgctt tttaccagta ccacacaaat agctatatga ctataaaggt tggcttaaga
     7861 aggttcagat ttaaccgagt gtgggaaaaa gattaccaat ctagctgcca aaatacgggg
     7921 tctcgtttga ctatttttcc ctattgggat ataatgagaa cagaaaaagg gcagttgctc
     7981 taaacaacta ccctatgcag aaccgtttaa gacggtggca tatctttaat tattaaaaaa
     8041 taatcgtcga cctaccaaag ttcagacggt tattttttat tgtttaatat gacgattgca
     8101 acgactaagc tgattaaggt aagtaagaaa ctaccaaaag ccagcatgag ttgaagggcc
     8161 tcgtaagtag acaataaaac gctcctttct gttggatttt gatgcattgc ccataggtat
     8221 caccaccttt cagaaatcag agccaccgcc ttagcttttc tgtaaagaac attattatat
     8281 cataatcaca caagaatccg tcaaatctta aactaatcag gcggcttttt tatgctctga
     8341 ctataggtct gaagagaaga tgctagatgt cttaggtggc tttccattta aactacgagg
     8401 tcttctttct cacagagtat agccccctct tttttcagct actgtttcgg aggcaagctg
     8461 gcatttcgtc taaattgctt ttgtttttcc ctgagcattc gaaaaaatcc tttatttcta
     8521 cctgacatat cactaaaaga gggtcctgtg accctctttt atagctatct gttagagaga
     8581 tatgcaattg ttagtcttgt tttttcttca agcctaggac acctgcgcta gcaatgacgc
     8641 tgagagctgc aagggtgaaa aatgggtgat ttgcctcccc cgtagctggt agcgtgccct
     8701 tttgagctgc tggagccgct gatttgtttg gtgctgactg aggagctggt gcctttggac
     8761 tagctggctg ctctgaagat tttggtgcct gtggagcagg ggattgctcc ggtgcctttg
     8821 gagtctctgg ttcttttggt gcttgtggtt gctctttttt ctccggtgtt tctggagcct
     8881 ttggcacttc tggcaccttt tgtgattccc cttgttgacc tggcactcct tgtggcccag
     8941 tatcaccttt tggaccttgt tgacctggtg cgccttgtgg gccggtgtcg ccttttggtc
     9001 cttgttgacc tggtgcgcct tgtgggccgg tatcaccctt tggtccttga agtccctgtt
     9061 cgccttgtgg cccagtgtcg ccttttggtc ctggttgacc tggctctcct tgcgggccag
     9121 tatcaccttt tggcccttgt tgacctggtg caccttgtgg gccggtatca ccctttggtc
     9181 cttgaagtcc ctgttcgcct tgtggcccag tatcaccttt tggcccttgt tggcctggcg
     9241 ctccttgagg accggtgtcg ccttttggtc ctgggagacc tggttcacct tgtgggccga
     9301 tgtcaccctt tggaccttgt tgacctggct ctccttgtgg cccagtatca ccttttggcc
     9361 cttgttggcc tggttttcct tctggtccct gtgggcctat tggtccacgc tcaccaactg
     9421 gtccgcgttc ccctcgaagg ccttgaggtc ctgcgggacc cattggacct tgaggtcctg
     9481 gtatccctaa tgaatctttc tcatacaatt tgtataattg ctctgattgg cctgtcgatt
     9541 tttttaaaaa ttgctccact cgccatagat atcttaaaac attttctagc attcgaccat
     9601 tgttataatg tgtcgaagtt tcccagtcac ttgagctacc agaaccagga ttaagtattt
     9661 ctttttttat gaactgttga aagaaatatc cttgattata catagaagga tatgtaaagt
     9721 cttctgccct tacatcattt ccaatcccta agctagctat ggttgctagg gcgacaactg
     9781 ctgagcagat accgtacttc tgaacaagcc tgatacttgt tttcttgttt ctcatgttta
     9841 tctcctttta gtttagaaat gttaacgatt tctaatcttt tttcttccaa agaaaatctt
     9901 aacatgacgc ttgcgggctg tgaatatgtt ttggggaatt cgcttccgta gtttcgtttt
     9961 tttctaatca aagggtcaat tgtctgacgc tagtgtcttt tggcattggc ctttagctta
    10021 ggaagactgc ctatgttagc aagcttttca ttagcttatc cgttttgata aagggtaagc
    10081 gacgaggata atctgacttt gtcttttgct tttgttagat tttttaatgt tttttgatgt
    10141 ctgatgactt ttaaaaaaag ccttcttttg ataggcaagc ttaaaaggcc taggcaaaag
    10201 cccagaccct tgctgctatt atctgttatt gtggaaagct accgctcttt ggcactgtca
    10261 tgcttaaaaa ttgcgacttg agctattgta accatagcgc tcaaggaaat cctgacgaaa
    10321 ctctaaaagg ttatcgtcca agatagcttg acgcacctgc ttcatgaggt ttactaagaa
    10381 gtataggtta tggtaactgg tcaagcgcat gccaaaggtc tcatcagcct ttaagagatg
    10441 acgcaggtaa gcacgtgtgt aatgctgaca ggtgtagcag tcacaatgat ggtcaagtgg
    10501 ggtaaagtcc tctgcaaact tagcattttt cacaacgaga cggccctcgc tggtcatgca
    10561 ggtgccattg cgagcgatac gggttggcag gacgcagtca aacatgtcaa ccccacgaat
    10621 caccccatca atcaggctat caggtgcacc tacccccatc aggtagcgtg gcttattttc
    10681 aggtaaaagt ggcgttgtaa aatcaaggac agcattcatc tcagcatggc tctcaccaac
    10741 tgccaagcca ccgatagaat agcccggaaa atccatgctc acaaggtccg cagcagattg
    10801 acgacgcagg tcctcaaagc cagctccctg cacgatacca aagaggcctt gatcatgagg
    10861 acggcggtga gccttcaagc cacgctctgc ccaacgactg gtgcgctcaa tggatttttt
    10921 cacataatca tagggctggt aaaattgcgg gcactcatca aagctcatca taatgtcaga
    10981 ccctaggtta ttttgaatgg agatcgcttt ctctggtgat aaaaacatct ttgagccatt
    11041 caggtgattt ttaaaggtca ccccctcctc agtgatgttt ctggagtctg ccaaggaata
    11101 aacctgaaag ccgcctgagt ctgtcagaat tgcctgatcc cagttcataa atttgtgaag
    11161 gccgcctgca cgcgcaatca gctcatctcc tggtcgtagc cataggtgat aggtatttga
    11221 caaaataatg cctgacccaa tctccttgag ctcctcagga gactgtgtct taaccgtcgc
    11281 ctgtgtccct accggcataa acatgggcgt cggaaaggtc ccatgcgggg taataatctc
    11341 accgagacga gcacctgtat gcttttcctt tttgatcaaa cgataagtaa tagggtaatt
    11401 agtcattgtt tcttttttcc ttgctatcaa gataaacagt cttgagcgtt ttgcatacca
    11461 cttacaaagc acttagtcaa gcggtatggg cttgtttaga gccctatcat tttatcaaaa
    11521 aatctctgac ttgtcatgcc ttcaaagaga caagatcccg aagcaatggc acgacagacg
    11581 catgaaggag ttttagcaag aaaagaaagc tttctgtcgt tcaatgttca gctatttcaa
    11641 gtatatgtct tatcttttat aaactttact acagaaaaat cgttgaaaat gtttgcttta
    11701 ctctatacta tcattcagaa atagctgttt cgcgcgtttg tcgtgagcaa ggacggtatg
    11761 ggtatcactg gctcctagaa tatggtataa tgtaccaaag gagttgtacg atgtcaatta
    11821 gagaaataaa acgtgaagct agacagactt taaagggact aaaggggaaa tacctcttat
    11881 ttttagtacc gataatctta tctatttttt actcaggaat tgaggttcat cagacctatg
    11941 tgaccactca ggggattgag gtatcagtcg gggcaagcta ctttcctttg attgttctga
    12001 taatgctgac ggtctttacc ttatcagcag cctataccat gctagatgtt atccgctact
    12061 atcgtcgtga ggtctctttt tcagaggcaa cgatagcttt ttctggaaac ttgtttggca
    12121 aggtccttgt tttgttgatc atcaaagggc tcctatttat cctatggtct ttgatttgga
    12181 ttgttggctt ggttattcta acgattagct ctgcggcatt actgacaagc tacaatactg
    12241 gtgctgctgt gatgactcca atcatcttta tggttattgg ttttgtgatt tttattatcg
    12301 ggcttattgt ttatatgaat cgttattgtg cttacagcat ggctgagtac attctctatg
    12361 acaaggtcaa ggaaggcacc tatatgggtg ctattacggc aatcgaagag agcaaggaca
    12421 tgatctcagg ctataaagga aagtattttt tactacacct tagctttatt ggctggttta
    12481 tcctagtaat cttgtctttt ggcttgatct atatctacgt actgccttat tacaccactg
    12541 ctgatgtgac cttttaccac catttaaagc acattcacga tgaaacagag ctgccgatag
    12601 atgctgaaag gcttactatc acaggttcaa aagaagcccc atctgctatt agctagcctt
    12661 aacgatatgc ctctatgtct ctcatgacct tgttcagagt agacatagag gttttttgca
    12721 tgacctttga taactttttt atagtaaaaa agaggagccc atcagttgcc tatccaaagc
    12781 tagatgacac atctaacggt tggaaggctt gcttacaggc cctcttttag caatgttagc
    12841 ccaagactat cctaaagctg ctgaaaagct cctcggtcta aggcataggc agtcgtccaa
    12901 tggctctcac gatagtaaat aaagagctgg ctatctaata gctcatcaat tgaggctgct
    12961 gttggcagac ctgctaggtc aatgaaataa tcccctggaa gaagctgttg tagcttttcc
    13021 attaaggcgg tattaacagc ggtctttgct gctggtaatt gactagagat tgataagcct
    13081 tcaaaggtct ttaaatctat gttttctgac tctaaagctg attttaaggc tgatttgatc
    13141 aagtctaggc tgtattcagc atctaaggct tcatcgcctg atgagaggct attcatcgcc
    13201 aatacataca aagggcctgc tgccttatcc tgataggtaa tgacaagttg atggttcagc
    13261 aaatcagcta agtcatcata agtaccagtg ttctcaagag taatgtaata agtccctgtg
    13321 agccctaagt ccttgattgt ctctaaaatc ttgccttgga ttgcttgatt tttttcagtt
    13381 gttgccgctg ttagaccact atttgtaata gcaaagctct caatctcttt ggtagctgta
    13441 ttggtctctt ttagaatggt tagaatacta tctttaagcg ctagaatatc atttctaacc
    13501 ggtgcttcaa tagggctaga gatgtcttca aagaaacgat aagcagaacc gctgacaaat
    13561 ttattggcct gtccgctgct ttttccatag gtgtctaagg cagttattct aacaaatcga
    13621 cctgttgttg gtgtaaagct gactgttttt agctcagtat tttgcttcca atcagtgcta
    13681 tcgacaaccg ttgtccagac cttaccgtct gagctgatgt cgacctttgc agaatggatc
    13741 ataccattaa cacctcctgg gagataggca atagcagaga agtttttatc gtccttaaac
    13801 tcaacagtat atgacttgtc ctcagtaacc tgattaaata aggtatgcca ttgggtggcc
    13861 atatctctac catctaccat atgcttgcca gacctgcctg attgctcatt agcataggtc
    13921 accgcctgaa tatcatcaat tgagatgtag tgcattgtag gatcagtgct gtctgcggta
    13981 aaggtatagg taacgctgtc acttgctaga ctggtgccat gagcccgata gcgagcaaga
    14041 actgtgacag tgtcattgaa gcgctctgtg ccatcataag cctgccaaga ctggccatta
    14101 tccagactga cctccaaatg ttcaatagca ccaatcaagc gattttccaa gtcattgcca
    14161 taaaggctgc tgttggtcgg tgctgctgcc tttgtcaggt taatcctgta ggtagcagat
    14221 accgcgtcaa agccaactaa aataccgtcc tctatattaa gcttggccaa aaggtcatca
    14281 ctaaaaacga taaccttgtc cttggtttca agccatgttt tcccattatc aatagaatag
    14341 cggactgtca aatctgtatc ctgataattc tcatgcaaac gaagggtctt gtcatcaaag
    14401 ctaaagcttg ctgtttcgat tggattgccc gttaggatat agttggcgat aattctaacc
    14461 tcattagatt ggagcacttc cttatcagtt gctgttttgg ctgcgattag agcgttatag
    14521 ctcagtaaat ctagctcagc cttagctgct tgatcgctga tattaggcgt gatacgcttg
    14581 atagcctcta ccatgacctg tggatagtag gtgtaagctg caatgacacg ctttcctaag
    14641 tccagccaat cctgatctgt tttttggcca ttttttgcat aggcctctat caagccatcg
    14701 taagtatcta gattaagctc tagtacatct aaagccttgc tgtaggcctc aatctgttga
    14761 tcactgccag cctcgtagac attagcgatg agattataat aaagcgattc cttgaactta
    14821 tcgtattggt ttaaggctgc ttgcgccagc agcatatagc tagcgttttt atgaatgtca
    14881 ttgtaggatt ttaggcccca gccaagcaag agcctagcct ctgttgctgt tgtggttccc
    14941 caacgagaat aagagattgc ccagcgatta ccataaacat tgtctctaat atcccaaatc
    15001 ccgttgccct gatcatcttg acggtaaacc aaataagcct cgtggtcatt ttggtaaata
    15061 ttgaccgctg gaataccaaa gacctcattg actgctacac ctaaatttga taatccccag
    15121 caaacagccc ctttttccat cagcatccag atccggtgac ggttgtcata agtaacatta
    15181 aaggcatcgt cattgagggt gccaacgagc tgatattttt ctgtccattg agcttgattg
    15241 tcagcgctgc gcatgtctgc gccaccgtag ccgatgtttt tgtatttcgt ataagagtag
    15301 ccactggtat agctagcaac cttatctcca tatttttgtt cggcgtaatg atgcagccag
    15361 agaatttcct catcatctat tttggcgtcc ataacagcac gcaccaactc catattgtag
    15421 ttggcgaatt cttctttcct caagaattcg ttgtctcgat acaattcttt aaaggcttga
    15481 tatttcagca ccgggtcaga agcaaggtag gtgccaccat agttaaccac aaaggatttg
    15541 atctccttgc agtaggcaac agcagttgcc agcatcattt ttttgtagac atagccattt
    15601 cccttgtcct ccaaatctgc cttattagta gcataaaggt ctcctaaggc gttcaaggtt
    15661 tttagggtag agccgttaaa catcgagcct gcctctaaaa acagtgacag agcgtcctca
    15721 tctgacaata gccaatcaag agcgaccttg accttttcat ttttcttgac agcagattga
    15781 atggtgtggt agccgacacg attgacaaat tcgcgctcaa gcactaatgc caaattgtct
    15841 ggattatcat aattatctgt gacactattc ttgctgagaa gggcatcata ctcttcagtt
    15901 gtctttagcc tgtcataaga cacctcgctt gataaatcat aatctgtctt gagcaacctg
    15961 agatccgcat aaacagagtg atcattaccg ttatttttta gtgaatttgc aattagcttt
    16021 acatatttag cacctgtaat atctagatca acataaacag cctcactggt tccggttact
    16081 gtaccagttg tcaccaggct ttcccaactt tttccgtcct tagacttata gatgttaaag
    16141 ctaacaccat cgtccttacc acgtctacta tagtcaactc ctaggtaggc tgatagacgc
    16201 gtgtattcat tggagtattg ttcaacatca taataaagct gtgaaggagc atgcactgca
    16261 attcccttat caaatgcaag cacctcgcca tcaactacta gagtaatggt gccaccggca
    16321 gggtttttgt cctgtaaaaa gctgccatgc ccaaccttgg acgggttgac acgtgtctca
    16381 tctgataagt agatatagtc cttagcttca gtcttattgg tggtctctac tgcttgtgat
    16441 acttctgtct gctcctgctt tgtggtctct tcggcagaag cttcggtagc ttgctctgct
    16501 gcggctactt gactcttaga gtcagttgtt tctgtagtgg cagtacctat tactactggc
    16561 agcgtttctg aggagccctc agctgctgtg tcttgcgcag cggttgctga ttggtcagct
    16621 gcttgttgat caaccgcttc ttgtgcttct aacgtggttg ctatggctgc actagctgtt
    16681 acttgctgct catcagcaga aacagttgtc agccctagtg ttaaaaataa ggttgcaacc
    16741 aacacagagg ctgcacctgt tttaaaggtt ttaatggcaa agcgctgctt accatcagta
    16801 taaggtttga acatggtgtc ttctccttta aaaataagat atttaagcaa aataaagact
    16861 gaccaccaac cactacagtt gataatcagt ccaacaaaga tatcgtacta taggaaatta
    16921 attaaagggg gaaaatcatc gcctacagtt aatttgattc tttgcgtctt gacacaatag
    16981 caagctggcc tgcacaagca ataactgcaa gagctgctgc tgtaaagaat ggattagctg
    17041 tatcagcagt tgccggaagc acttgctgct tatcagctgc tttcttgtcc tccttcttag
    17101 cttcaggctt agattctggt ttaggctctg gcttaacctc aggatctgat ggttttactg
    17161 gatccgctgg gtcgattgga tcgaccgggt ctaccggatc cactgggtct accggatcca
    17221 ctgggtctac tgggtctact gggtctactg gatccactgg gtctaccgga tccactgggt
    17281 ctaccggatc tactgggtct accggatcca ctgggtctac tggatctact ggatcgaccg
    17341 gtttagcaac caaggctgcc ttggcatctg agagggattt cttagcattt aacaccttaa
    17401 ccaagctgtt agtaatagct gtcggttctg tctcctgagc ataagctgtc tcacccgctg
    17461 ctgcgacctc cttagcctta gctagctggt ctgtataggc ttgagcagaa gctgctgtat
    17521 atggagatag gtctagattt tctccgataa gagcatttaa ttggtctaaa gcagaacgca
    17581 attttgcctt tccttcttcg gcaatcgcag cctttacctt taaaatagta tcaacaactg
    17641 aatttgtttc tgtagtgtag cgctctagct cataaaggga aatgtctttt ctctctttat
    17701 ccttgttaac agttctatag aaggtacctg ctgcttcaat ggccttattg tacaattcct
    17761 tcaaagactc tgatgtcaaa gcaagatttg gattttctcg gtaaagctct aacagcttag
    17821 ccaaggcttg atctaaggct tcatgcgcta cagcagtctt aagcgtcgta agagcttgcg
    17881 ttaaatcagt cgcagcctta tcaacatctc cttgtgaagg accaaatgaa ttttgaagct
    17941 tagctgccgc tgcaagcttt tgcacaagac cgtcatacgc ttctttagga tactctttgc
    18001 catctgttat aaaaggtgta gcttgattaa tagcttcatt taaagcatta agattaacaa
    18061 gactagtaat agcggaatca atagtagtaa cagattgatc tactgtattt tgatcagggt
    18121 cactgtttaa ataggtctta ccaatagtaa ccgctgattg caaggcttgc agtgattcat
    18181 cagaatacgt tccttcaggc tggctgagtt ttagcttagc ctcctctaac gacttcctta
    18241 actcagtttt attgctgttg gaatttttta gtttaaatgt gaagagcttt ttggtatcat
    18301 ttttcccata gaatacccaa gctttaatag tataagatcc ccccggtaca gcatatgtag
    18361 gcgaagctaa catttcatca gttaaaaagg aagtacccgc agcattgtaa aagtcaaacc
    18421 atatttttac tccaggggta tcaattcctc ttgaaccatc tccattcgaa ataaagtcaa
    18481 aagtatctcc atcattaaca gtcccattac tacctttacg agtaaccgta atttgactca
    18541 taagatctga gatagtaatt ggttctccta attcaactgt atattcttgt ggaatatcta
    18601 tgtgccagtt cagatgttga cctgtcccat tattttcaaa tgcactagca gtagtcgttt
    18661 ccgcccctac tgttaaagcg ctatcaatat tatccgacaa ggcaaccaat cctgtgctga
    18721 aaactaatcc aacaagacca cagcccttaa gacaccgttt cgtgaatttc ttcattcttc
    18781 tttttccttt tctagagccc tagcaggctc gaacaatagc aatatgtgtc atagggcagc
    18841 tgctatcact agtagctgcc actttgatat tagcctgatt gtgacactca aatatcactt
    18901 ataatttaca aaaaatttta agaaaagtca atatacaaac ggtttttgtt aaatttttta
    18961 aaaatataac aaaaaacaag cacgccaatc tggtctataa cagtttttat tgtcaatagt
    19021 gatcgctaaa gggtttttca gccaacaaaa aaagagtgag tccctaactc tctcttctag
    19081 actttgtgcc atatcatcag ctacacgaac agccaagatc aaaaaggcca gctctcaata
    19141 gtctgtgtcc ttaccctgct tcgtctgaca gctagggcaa acaccatagg ctataactgg
    19201 aatacgggtg accttatagc ctgtttgctg gtgtgcttcc ttagcgatat ccatcacatc
    19261 tacgtccata aaatcagcga ttgtcccgca aacctcacaa accacattga catgctgatg
    19321 tcccataaag tcataatagg tcgtcaaatc attactaatt ttcagctcgg atacaaagcc
    19381 ctcatcaacg agaaccttca aattattata caccgtagca aggctcatat tagggtattg
    19441 aggctgtaaa tcacgataga ttttatctgc gctggggtgc tcagtggact gaatcatgta
    19501 agaaatgatc gccttacgcg tctcggtaat acgaatatgc ttgtcacgta gatgctctag
    19561 gacattttca taggcattta gagcttgctg atgtgaatga atgtccaagc ttacaacctc
    19621 ctccttttgt aactatggca ctaactagca ggaatcttga tcctgcttgc tgattagccg
    19681 taaatagtca atcttgatac agcgattcat aacaatgtca gctttgcctg ctgatcgcaa
    19741 aagctcctca gcttcttggc tatacaagcc aagctgtgcc caaaagacct gaccctgaca
    19801 agctaaaaag tcctgagcaa cctgaggcaa atactcactt cgtcgaaaga cattggcaat
    19861 atctacctta aaaggaatag ccgcaaggct agcataaacg acctctccta aaacagactg
    19921 acctgccagc ctaggattga cagggacaat ccgatagccc ttagcctgca taaacctagc
    19981 cacatcataa gcagcagtgg tttgacgatc agataagcca accactgcaa tggtcttgga
    20041 agattcaaga taagaggtga tagtctcatc agagggattt tgaaatgtat caatcatcat
    20101 ttacttcctt tttatcaagc acacccaata gcaaatcaac aacaggaaaa gacaatcgct
    20161 gccggtatga catagccaac catctggcta ccaagctcaa ggaaaaccct ccttagcatg
    20221 acatgccctg ctgttttttt ctcttcatta tagcataagt ttttaaaatg cggaacacaa
    20281 ggaataacag cagccacacc aagcaggctg ccacttaaca ccactgctaa tctagtctac
    20341 ttggcctcat accagctctt gccggcactt tcgtctacac gcagcggaac tgccaggctg
    20401 acagctgatt ccatcgtttc tttgaccagc gctttaacag ccgctagctc atgattaggc
    20461 acctcaagca caatctcatc atgcacctga agcagcattt tggtctcaaa gccaccagct
    20521 actagggctt ggtcaagatt tatcatcgca attttgagaa tatcggctgc actgccttga
    20581 atgggcgaat taatggctgt acgctctgca aaggagcgaa cgttgaactg acgagaattg
    20641 atatctggca attgacgacg gcgcttaaag agcgtctcaa catagccctt atccttggct
    20701 tcacgcacaa ccctttccat gtaagccttg ataccagggt agcgctcaaa gtaggtgtca
    20761 atataagcct tggcctgttt tcttggaatt ccaaggttat tagacaagcc aaagtcagaa
    20821 atcccataca caatgccaaa gttaacagcc ttagcattcc gacgatcatt ggcagtgacg
    20881 tcctctggct tttcaatgcc aaagacacgc attgccgttg aggtatggat atccgctccc
    20941 tccttaaaag cagcaatcaa atgctcatct cctgaaatat gtgctaaaac acgcaattca
    21001 atttgcgaat aatccgagct aagcaaaaca gcatcatcat gagatggagt aaaggcctta
    21061 cgaatcaagc gcccctgctc cagacgaatc gggatatttt gcaggttagg atcaacactg
    21121 gaaagtcggc ctgtctgggt taaatcctgt aaatagcggg tgtggatcct gccatcagcc
    21181 atgatgtaat cctgcagtcc aatcacatag gttgattgca gcttagtaat ttgacgatag
    21241 tccaagatct tagccacgat tggcgcaatt ggcgctaagc gctccaagac atcaacagcc
    21301 gttgaatagc ctgtcttggt tttctttgtc aaatgaagag ggagctgcat tttctcaaag
    21361 agtatcactc ctagctgctt gggagaatta atattaaaga cctcaccagc catttcatag
    21421 atttcctgtg tcagttcctc aatgaccacc ttattttgct ctgccatttc ctgcaggcta
    21481 tcttgattga cagcaatgcc ttcgatttcc attttcgcaa ggacattggc aagcggcagt
    21541 tcaatgtcag tgtagagatc agcctgctca tgctctgcca gcttatcaag catgactggt
    21601 ctactatcca gcaagacctg aaccttacgc gccagatgtc ctaacaaaac agccttgtca
    21661 ggcacagcac gcttgacccc cttaccatag acaacctcat ctgtatccag tgatatagtg
    21721 gtataaagac gtgccagagt agccatctca ttgtcctcta cagttgacaa gaggtaatta
    21781 gctaagcggg catcatagct ggcagccggc aaatcaagcc ccagatgact aagcagaacc
    21841 ttactgcgct taaaatcata ggtagcaatc ggctgctcaa gaaccttttt aaagagcttt
    21901 gtagtgagga gactaatatc tgctgaagca taaatctggc cttggttgcc ccaagcaaag
    21961 ccaatcagct cctcgcggtg ataattatcc ctcaaagctt caaaataaaa caccgtatcg
    22021 tctgaaaaca tgtccgctct tatgtcagta acttcctgat aagcaatctc agctaccggc
    22081 tcctgtggca actgactagc taaggcattt tttagttgaa caaaatccat ctcatcataa
    22141 aattgtgaca agcgatctag atctggaccc tgatagacaa tatcctccaa tccaatcgta
    22201 atcggagcgc tagtgttgat agtagcaagt gtctttgaga ggaaggcctg ctccttatca
    22261 tgaagcaggt tttccttcat ttttgaaggc ttgaagctat caatatgctc gtaaatcccc
    22321 tccaagcttc catattcgtg caggagcttt agacctgttt tttccccaat tttggtcact
    22381 cctggaatat tatcagactt gtctcccatg agcgctttca agtcaatgaa ttgctctggc
    22441 gtaagcccca ttttgtccat aaggtaggct ggggtaaact cttcaaattc agcaactcct
    22501 tttttagaaa tctcaacaac ggtatttgca tctgtcagct gaatcaaatc cttgtcacca
    22561 ctgacaatag tcacatcaaa aggaatctct gtacgctctg ccattttatc aagcgttccg
    22621 ataatatcgt ctgcctcgta atgctctagc tcataaaagg caataccaag cgctcccagc
    22681 atatcacgaa tataaggaaa ctgctcccga aattcatcag gggtcttggc acgtcctgcc
    22741 ttgtaatcag caaaaagctc tgtccgaaag gttgttttac ccgcgtcaaa ggccaccaag
    22801 acatgcgtcg gctgaacacg cttcatcatg tggtctagca tcaaatgaaa gccataaatc
    22861 gcattagtgt gaagaccgct gtgattttta aagcggtcaa tctggttata gagggcaaaa
    22921 aaggcacgaa aggccactga ggagccatca atcaaaagta atttattctt gttttccatg
    22981 cctttattat accacacagt gacctgcttt gctctgacca gctacgcttt ttgcaagcac
    23041 tagcaggtaa agcagcatac ccgtagcttg atcaaaagat ccaagctgct tgaaggaaga
    23101 taaatgactg cttttgcttt atcatcaaga catttctacc aaaaaagaga ctgagataaa
    23161 aagagtgaca ctttagagag tcttaactaa tatcctttgt tatctaattc attaacaaac
    23221 gaacaggcct agttttcaaa acctcagaaa actaaacctg ttcatttgtt ctatttgaag
    23281 tcagactttg tctcaatctc caaattgatg acatcatctg ctatgacttt cctaagctga
    23341 tatggacgga aagccttctg caaaatccat gattagtcta ggctacattt gagcgagcgg
    23401 ccttatgact gagtccattt ggccacctta tcagcatggc tagccaccca tttcttggct
    23461 gcggcttctg gtgtcatgcc ctgattgatg tcaagcataa cagcctccat atcctctttt
    23521 tcccaatgga agtgatcaac aatcctatga acagctggca ggtcggcctt taagccccga
    23581 cgtgcaatgg tattgatatt ttcctttgag ccaaaggttt tctttggatc tgccaggtat
    23641 ttcaaatcgt acttagcaaa catccaatga ggagaccaag ccgtcacaac gatcggctcc
    23701 tttttcttga ccgcctgatc aagtgaggtg gtcatagcac ctgtcgaagc agcaacgagc
    23761 tcccaatctg ccaagttgga ataggccttt tgcgtcttat cagcagcagt cataatacca
    23821 gctcccggtt caatcccaat aatctgttga ttggcttgat ccgaaagctc ctctatgctg
    23881 ttcacatcgc tcatataggc tggcacagcg agtcctagct ttgttccctt cagattagga
    23941 ccaagattat ccagcttatc ctgatacttt tggtactgct gctgatgggt cactggtaac
    24001 caggcacttg ttgaaaagtc tgcatcgcca tttgcgatgg tttgccacat cacagcatta
    24061 tccagtggtg tcaaggttac ctgataaccc tcatctctta agacctgagc gataacatgg
    24121 gtagaagcca cctcagaatc ccactgcaca taagcaatgg tcaccttctg ccccttgtct
    24181 gctgagcttg ataacatcgc agcaaagcca cgccccaaag ctgacaacaa aaagacagct
    24241 aaagcagcta gaccaagcca tttcttggtt tttccagtct gcgttctttc ttgcggctta
    24301 ccgttaaaat gctgagtcat acgatccaaa ataatcgcca agataacaag ggccaaacca
    24361 ctaacaaagc cacgcccaat atcagcatgc tgcaaggccg ataggacctc acgtccaaga
    24421 cctggagcac caatcattga gcctgtcaca accattgata gggccaacat catggtctga
    24481 ttaacacctg ccatcatcgt atgctttgcc aagggtaatt cgaccttcag taatttttgt
    24541 ttaggggttg acccaaaggc atctgaagct tcaaccaatt ctgtcggaat atgacgaagc
    24601 gctaaattgg taaaacgaac agtcggcggc aaggcaaaga taaccgacgc aaagacgcca
    24661 gggaccatac caatgccaaa aaaggcgaca gccggaatca aataaacaaa ggctggcatg
    24721 gtctgcataa ggtccagcat tggattaatc acctggtgaa caatcttatt tttagccatc
    24781 caaatgccca agggaatacc aagcaagaca gagatgaggc ttgctaccaa aaccagcgta
    24841 aaggtattga tcagctctgc ccacaggcct tggttataga caaataacag gcccaggagg
    24901 gtaaagatcg gcaaaggcca tttttttctt gccaagaaaa acatcgcaca ggtaaccaat
    24961 agcataaaca gtaacggatt gataaacaaa agggtctgcg tgatccaatc catcaaagca
    25021 ttgcccacaa gctgcagcag atcaaagaag cctgaaaagg tttttgtcag ccactcagtt
    25081 agttgctcaa ccagctgtgc cactggtaga gttgtttgta ataggttttc caaaatacag
    25141 tctctccatt ctaattaagg tcgtcatctg gaatattagc caaggcttca aggacacgcc
    25201 cacgaataat aacccctaac aagcggtgct gctcatctgt cactgcaatt ggcgcagaag
    25261 agtcataaat caagggcaaa atatccgtaa taacagtatc ctttgagacc gttctgacat
    25321 tacgatcaat aacctctgac aaggggagct ttttctgacg tgcttcaatc gctccgtctg
    25381 ctgttaggct tcctattagc tgacgacgac gattggttgc catgagcata gacacctcct
    25441 cattgtgcat acgattcaaa gccacctgcg gaccgtccag atcaaccgtt gttgtgatag
    25501 gcttaatcat aatatgctga gcagtcagca cctttgagcg gtcaacgtcc tctacaaatt
    25561 cacgaacaaa atcattagcc ggattggtta gaatatcctc acccgtccca atctgcatga
    25621 tctgaccgtc cttcatcaag gcaatacgat caccaatacg cagagcctca ttcaagtcgt
    25681 gactgataaa aataatggtc tgcttcatcg tctcctgtaa ttctagcagc tcatcttgca
    25741 tgtcacgacg aatcaaggga tctaaggcag aaaaagcctc gtccatcagc aaaatcttag
    25801 ggctgtttgc caaggcacgc gccaagccaa cacgctgctg catgccacca gacaattgat
    25861 cagggtattg gtccctgacc tcaagaagcc ctgactgatc aagcgcacgc tttgcaatct
    25921 ctcgacgctc ctgctttggt accccacgca gctccaagcc aaactctgtg ttttccaaaa
    25981 tcgtcttgtg tggaaaaaga gcaaagcttt gaaaaaccat attcatatca tgcctgcgaa
    26041 cttctctgag ctgatccaca gacagtttag aaatatccct tccctctaat aaaatagagc
    26101 ctgctgaggg ctcaattaat cgattaagca tacgaacaag cgttgatttg ccgctgcctg
    26161 aaaggcccat gatcacaaaa atctcgcctt cctgaacctc aaagctggca tcatagaccc
    26221 cgacagtaac tcctgtcttt ttaaaaatag cgctcttact tttaccagcc ttgatcattt
    26281 caagagctgc tttttgtttt ttgccaaaca atttactcaa atgcctgacc tctaaaatag
    26341 ttcccattct tttcctctct tgttctcttc ctcgattaaa gctaaattag cttaatagat
    26401 ttctaaaagt gccaccacaa ttttaaaata atgaggtcac tttttgctta aaaaaaagag
    26461 tctgcctaaa cagaacacat taattatata atatatggtc actttttgtc aagctggacg
    26521 cttgctaccc aagtatcagg atcgtcctaa gcagtgatat cactagtcaa ccaagcactt
    26581 aacagccctg aacagaccac agcaagcagg cctttctgac acttagcgcc ttgagagctt
    26641 acccagcagc ctcctctagc tgacttgatt gacctatctg actcttgtcc tgcaaccaaa
    26701 ccaatgctta gactgccaag caagctccca atagcaataa gatctgctaa gcaaagcgtt
    26761 agcttgcttt gaccatagct gctagtcatg tctaatagca ctctagataa atcaaaagcc
    26821 ccacctagca aggctagatg aggcaaaata ggtttagaga agggctttaa actgaatatt
    26881 tgagtcttcc aagaagcagt cgtcaaagcc acgtgggtga tgatactcga tgcgatcctg
    26941 atcctgtgga taggtgtatt tgccaccaac ctcccaaatg aatggatgga attggtattg
    27001 caagcgctcc ttacgcatct tccaaagctc taggatttca tcagttgagg ccatgaagtt
    27061 tgaccagata tcatagtgaa ccggaatgac aaccttggcg cggagatttt ctgccatacg
    27121 aagtaggtca acagaggtca tcttatcctg aataccgatt ggattttcac cataattgtt
    27181 caagacaaca tcaatatcgt agtcacgtcc atgcttagca aaatagtttg agaagtggga
    27241 gtctgcacca tgatagatgg ttcctcctgg tgtttcaaaa atgtagttaa cggttttgcg
    27301 agctaactct tcgtcagtca ctggaagtcc tgctagctcg ccaccatttt cctcagcgcc
    27361 agcaactggt aaggtaacga tacaggtacg gtcaaaggat tcaacagcag taaccttgat
    27421 atccttgaat gcaaagctat cgcctggttt taccacgatg atacgatcct ttggaacacc
    27481 ccagctctcc caaatcttgc cgcactcata agggccaaca aatttgacat ggtcaagctt
    27541 tggattgttg ataatggctg ctgcagtatt gatatcaatg tggtcactat gataatgaga
    27601 caccaagtaa tagtctaact cattaatcat aaagggatca ataaccattg gctgagctct
    27661 tagatttggt tgtagcttgc gaacccctgc catattggcc atttggtgac cacgaaccat
    27721 gtcttttact tttttagttg cctttccacg attggaccat aggtccatga caacattggc
    27781 accacccggt gttttgatcc agataccgca gttacctagc caccacatag agaaatttcc
    27841 ttcaggcact acctcttctt caatttcttc gtttagccag gttccccatt ctgggaaggt
    27901 gctaagaatc catgattcac gagttatatc ttgtacttta gccattatgt ttcctccaaa
    27961 atgaattttt atctatactc taagtataga ccttctttat tctcataaaa agaccaagtg
    28021 tcacacactc ttgtgttcaa aactggactg aattttggct caaaataaac taaaagcccc
    28081 agccttctcc taaaccaata gacagctgag gggtccttat caataggcaa gctagtagct
    28141 tacaataatt cgtgatgaat gagcttttca atttttgttt tcaaggcata gcggtcagca
    28201 tcgtccttaa caatggtctc gatcgccttt tctagctcaa gggaaaaacg agagctatca
    28261 ctcaagcgcc cctgctttga aaaacggatc aatctaataa tgtcatcatc gctcaaaata
    28321 ggattgacaa tcagtacggg aacaagagcc tccagtgcgt ctgttgttga taccacaatg
    28381 tcaacagaca tcaaatcaaa gacactctgg tattgctctg ttgtaaagac agcctcgatt
    28441 tgacaattgg gcaaataacg ctggcactgc ttcaacagca gcttttgaat cccaatgcca
    28501 tcatctgaaa cgataacaag cttggtcttg tcccagtcag catgactatg gcgcagctct
    28561 cctcccagat gaatcgttag ataagccacg tcatcatctg ttagacggat ctgccaagcc
    28621 tgctctagga ttacagcaca ggattgagcc atagcaaaga gctcctcgta tttttcctta
    28681 atatggtctg ttaaaggatt gatcgaaaaa atcccatagg cctttcgata aacaagggcc
    28741 ttgcaatgcc tggtcagctg tctaagcaag tcctttttgt gggtaaaatg cagctgatag
    28801 cgcagctcca gctgatcgat aaaatcacca atagtggctc gcatctgctc ataatcctga
    28861 ctttcaacat ggtgatcctg atcttttcta aaggatagca tcagcatggc tatcatgcct
    28921 acctcaatgt catctaaatg cagcttgaaa ttgtggtaaa gctcactagc caatgcctta
    28981 gcaatctggt attccttgcg cttccaaatc aggttaaaat cccttttaag cgctgtttta
    29041 gtttccgaat gcaattgcat gttgcgatag ctaagcagga taaaaggaag aatttgcagc
    29101 ataaactgac tatcctgaat attaattgtt ttgcctaggc tagcctgaga caaaaagagg
    29161 tattcgtgaa aataatccaa aacctccttt gaaaaataag ctgacaagcc ttgtgtctca
    29221 gaaagcttat gatcaaaaag ctcaataaag ctgctattgc ctccctgata aacacctgcc
    29281 aataccttgt aaaggtactg aatcaaagcc atagggtgac agtcaaagta atagcccttg
    29341 gccttggtgg catgcagctg aatcttattg ttatagctag acaattcctc tctcagttca
    29401 gcaaggtcat ttaagatggt atttctggaa acatcattaa tcatcatgag cttatccagt
    29461 gtcacccgct ctgttgccac tgcaatataa atcgctgata agctcctgcg ctcatcaccc
    29521 ttcatgacat agtgataatc tgccacttca ttgaggagct gttggcaggc agccttttgc
    29581 tcactattta gcaagatgcc aacccgagga taggagacaa tttgagcaac atggctgggc
    29641 agcgcttcgt taattttatc caaatgataa tagattttgc gccgcgactg acccaaggca
    29701 gctgaaatcg ccatgactgt ctcagcctcc ttcaatcgaa tcagatatga cagcagatca
    29761 tagctttttt tatccaaaat aatcacgttc atacctccct tctataaaac atcactacca
    29821 cacagcctta tcagtttacc attttaccta tctgtaggaa agaatactag gccaaagtca
    29881 atttctaaat aggaaaaaac gaacgatcat tagttttctg aagataaaat tcctaattag
    29941 ttcgcttttt tcttttataa ttgtaatagt tgaattaatt attaaacttt gtctaaaata
    30001 agaggctttt tatcccagat tgcaacaagg gttaacacct tgaccttaag cctagctaag
    30061 cagctctcac taagttacta gctgctgcct taatgccggc tacctttttg gccataatag
    30121 gcatttggac catgctttct aaggtaatgc ttgtccataa tataggttgg agctggctcc
    30181 acacgaggat tgatttgttc tgtcaggcgg ttcatcttgg ccacctcttc gagcaccact
    30241 gagtgataaa ccgctaattc aggcgtcttg ccccaagtaa agggaccatg attgcgaaca
    30301 acaataccag gcactgccat cggatcaaga ccacgactag caaattcctc taaaataacc
    30361 gtacccgttt ctttttcata ggctccatta acctcatcgg cagttagaga gcgagcacat
    30421 ggaatggggc cataaaagta atcagcatga gttgtcccat aaaatggaat atctcgccca
    30481 gcctgtgccc agccaaccgc ttctgttgag tgtgtgtgca caatcccgcc aacctctggc
    30541 catgccttgt ataattgcac atgggttggc aaatcagaag aagggttcag ctctccctca
    30601 acaatagtgc catctaagtc tgtaacgacc atattttccg gtgttaattg gtcatagtca
    30661 acgccgcttg gcttgatgac gatacgtccc agctcacgac agacctctga gacattgccc
    30721 caggtaaatt tcaccagccc atgcagcggt agggccttgt tggctgcaca gacacgttca
    30781 cgcatttctt gtagcctttt tgccattagc ttaaccccgc tttctcaatc agtggataaa
    30841 ggaaatcctg tgcctccttg atggcagctc ttgtctcctc tacagtttca cagttttctg
    30901 accacatttc aatcaaaaat ggaccatgat aatgcgtttt cttgagcaca tcaaacattg
    30961 cttcccaatc aacacagcct tgaccgaatg gcacatcacg aaattgccct ttagatgttt
    31021 ctgtcacagc ataggtgtcc tttagatgca aggcagcaat agaccgatgc ccattgtaaa
    31081 attcactcca gaggtcatta tgccaagcag agacattgcc cgtatctgga tagacaaaga
    31141 gataagggga gtcaatttct ttttccacag ctaggtattt ctcaattgag ttgataaaag
    31201 gatcgtccat tatttcaatg gctaaaataa cctgagcttc ctctgcccaa gtgcaggcct
    31261 gtctgagatt tttgataaag cgcgcacgcg tttcaggtga tttttcttca taataaacgt
    31321 catagccagc caattgaatg gtacgcacac caagatcctg tgctagcaca atgcattttt
    31381 tcattagctc taatgatgtc gcttctgttt ctggattgct agagccaagt ggataacgac
    31441 gatgaccaga gaagcaaatg cttgggatac gaacccctgt ttcataaata gccttgacaa
    31501 tgtctagtcg ctcctgttta ctccaatcca agcgcgctag gcgagcatct gattcatcga
    31561 cagacatttc tacaaaatca aagcctaata cctttgcaaa ttgcaagcgt tccagccaag
    31621 taaaatgctt tggcgttgct ttttcatata taccaatagg acgcgccata ttgttacccc
    31681 caaatgcgtc gaatctcgtc tttaaaggca cgtgccgctg ctgcaggatc ctctgcttca
    31741 gtgataccac gacctgcaat aaaggtaaag acattaaccc cttcaaagag cttgagggta
    31801 ttgatatcta agccacccgt caccgataca cgaaagccca tgtcaatgag ggctttgacc
    31861 ttgttcagat ctttttcacc ccatacttca ccagcgagta gggcgtcacg tgattgatgg
    31921 taaatcgcct gtgaaatgcc tgcatctagc cacaattgtg cctgttcata ggtccaatca
    31981 ccatacagct caacctgaat ctcgccacgt tccccacgct cttctttgat ggctttcagt
    32041 gcggctgcca tggttggaat agtggcacag caaatacaag tcatccagtc cgcaccacgc
    32101 ttagcattat tcttagcaac agtaccgcca gcgtctgcac acttggtgtc tgctacgatg
    32161 atcttctctg gaaataagct acgcagcacc tcaaccaatt cgctgcctac ttgaagcagg
    32221 caaactgtcc ctgcttcgat tacatcaacc tcgtgaccaa ctgcaacagc agccctgacc
    32281 gccccctgca aatcagaatg atctaaggca acctgtaatt ttggaatatg tgtcatgatt
    32341 ttctaccaag agcccgtagc accgccttca atgcttaata gcgagctcct atcctttctg
    32401 ttgtgtttga ttcgtttagt gatgatggct tgtctaagaa tccaaatcca agccctctaa
    32461 ataaggacta tttttggact cgtccaccaa agccaaaacc tctgctggag tgtgacaggc
    32521 aactaagcgc gaaatagcgt cttccagttc aaaaagggcg acaatctgtg gaatagcaac
    32581 tgttgtatga atagaaggat cagttgccgc caaggttagc aataccgaag cctctttgcc
    32641 atctgaaaag gtcaccggct tggtcagtgt gataagagca aaggcatttc gcttgacccc
    32701 tacaccagcc tctgcgtgtg gcatggccat tcccggcata aggacataat agggcccgta
    32761 cttttctgtt gatgcgataa tagcgtcata atattcagag gtcaccgccc cgctgtcaat
    32821 caaaggctga acagctagct taaccgcttc ctgccagcta gctgctgaca agcccaagcg
    32881 aatagagttg ttttcgataa atgctttttt taaattcata taactatcct ttctaaatca
    32941 aattctttgg ccagacactt tttgcctcac tcctatctag ctgataaaga gaaagagctg
    33001 gaatctctct tcacaactct cactccatct atccttactg aaagttgatt gctacagctt
    33061 agcttacagc caagtggctg ctcttaggct cactatcatt tgccatgagc agcactgatg
    33121 tcatcagggc cgctctaaag caccgcctgt agcttggttt tgatttcatt gtcgtccata
    33181 agattatcta gtccaaccaa atgacccttt gtacgcccat ctaattcatg aatcaggtga
    33241 ttagaagcaa ccacaatatc atagcctgag gcaagtccct ttgcctcacc cactgagcaa
    33301 gaagcagact gaatatcagt caccccaagc tgacgaagtg cgttttcaac cttcatttta
    33361 ataaccattg atgaccccat gccattaccg catgctgtaa gaaccttaac catttatttt
    33421 cctccgaata tatgataatt tgatatgaat gaagacctgc agaagtatat cgacaaactc
    33481 ctaccagcct gtgctaaaag acgaataagc agctattatc accttgctta ttgtgcttca
    33541 ccgcggtagt aagcctcttt atccttagcc ctagcaaatt gtagctgtgg aatagcaagt
    33601 aagaagacac acaccaccac atagcctgca ataccaagga acttgaagag ataaccaaat
    33661 ggaagccaag gaagcaccag gtcaatattg ccatgataac cacctgtcaa gcccaacaga
    33721 ccaactgcca ctgcacctaa ggcaacctga agaatacctg atataaagga tagagcaaca
    33781 gctgccttcc agccaccacg cttatctgca taaacagcaa tcgcagcatt atcaaagaag
    33841 accggaacaa atcctgtgat gatcaagatt ggatttttaa agatcacaag aagtgcaata
    33901 gtgattagct gaccgataag cccaaaggta aatcctgaca aaacagcgtt tgaagagcca
    33961 aagccatatg acgctgcaac gtccaccgca ggaaatgaac ccggaaggag cttacttgaa
    34021 atcccttgga aggcattggt caactctgac acaaacatac gcacaccctg catcaggata
    34081 aagagataaa ctgagaaagt taaggaggtt tgcaaaatat acataaagaa ggcctgctta
    34141 gctggattaa aggcaccagc acctataagt tctgcattag acatcatatc tgggccaagc
    34201 acagccaaga tagcaccaaa gaaaaccagc attagagtgg cagaagcaac caccgtatca
    34261 tgaaaaatcg ttaaaaagct tgctagctta agattgtcaa ggttctcttc ttttttacca
    34321 aagaaaggcg ccaccttgtc aacaaaccag atcgcaaact gctgctggtg cccaatggca
    34381 aagcctccac cacctgtcaa gcgctgagtc gcctcaactg tcatattgga gctgacagcc
    34441 cagtaaaggc cacagataat accgaccgcc caagcaccaa aagcattttg aagctgaggg
    34501 attaaaagaa gaacaaacac agagatggtt gccgcctgct gcaccatgat atgacccgta
    34561 ataaagagcg tacgaacctt tgtcacctta cgaagcgcca ctagcaaaat attgacccca
    34621 aaaccgatca aaagggctgt ggtggcaacg ctgatggatc ccatctcctc tagcttggta
    34681 ttggctgctg caagtccaaa gtaagggtca ataactgcgg cctttaattc aaatttctta
    34741 cccaatgcca ctaggattgg gcgaaaggtg ttaaccaagc ccccagcacc aacattcaaa
    34801 atcagataac caaccgttgc cttaacaaag ccagcaaata cttcatgcag gggcttttta
    34861 agcagcaaat acccaatcaa aaccaaaaga cctacaaaga aagccggatt ttgcaaaata
    34921 tcttgcgaaa accagtttag gggagctata agcattttca taagaactac ctcttttcac
    34981 agttaataaa tatgatattt tctatacaat aattgtaaac gatgtaagcg tttaaaaaaa
    35041 agaccaacaa tcacacaaag aagtgttcaa aaatgtactg aagccaattt ccagctagct
    35101 ctgatcactg ttaaagcact atcattaatc tctaattaat aaccaaacac atcacaacaa
    35161 tatcgggcta acacaaaaat aggccagccc atactgccca gccaaaacga aacaagcaat
    35221 caattcaagg cacttaaccc tgttttatat cgtacaaagc ccttttaaga tgattttgtt
    35281 tgtttcctaa tcgtaaatta gttatctgat ccgttctctc ctcagatata ctcaccctta
    35341 tctaattcta ctgtcaaata gctacttact cataagcaaa tgaatattaa gcaaccacca
    35401 agctacaata aaagacctta ccctgttggc aagatcttat tcattataca atttttcctt
    35461 ctgcgacatg gactacctca tcacacaagt cttcaatatc tgtcttcaga tgtgagctta
    35521 aaatcacaag cccatttttg ctaacatcta aaagcaattt tttcgtttgc tccacgctcc
    35581 tgtcatctaa tgcattcatt ggctcatcta atataaggat cttagggtga tgcatcaagg
    35641 cctgaattaa ccctaatttt ttcttagtgc ctagcgatta atgcttaaat gctgtttgac
    35701 taaactgatg taaatgataa acatctaacc aaaaagctaa atcaatatct ctagccttag
    35761 gagagattga cctaagcaac tctagatttt gtaacaatgt taaatgtgca ataaactctg
    35821 gattctcaat caaaatccca gcatcctcga tataattatg gtactgtcta atttttttat
    35881 tgtcctgata aacagctcct tcatctaatt tgatataacc agctaaggcc ttaagtatca
    35941 aggtttttcc cgaaccatta atacctacca aaccatagat attaccttct ttaaaagtaa
    36001 gattaatatc atctagaaca aggttaccct tatacagttt tctaccatgt tcaatccgta
    36061 acatctcagc tctccttata ataattgtca taaagcatat gtaccaatac tattagcagc
    36121 aggcaccacc aaacatcaaa caaaaagtaa cgtatcaagg tgagactagc aaacaagatc
    36181 atagctacta cagcagatga ggcatagcgt atcataacat aaatcaagca aatatctata
    36241 gtaagccaag ataccataag ataacatagt cgttcaatat gatatggtgc accataatag
    36301 gtcatcaata cacctaatat taaaacgata aaaagtaacc actctttaat atagaaaatc
    36361 gtactcgtcc gccatagctt gttaaaaaat accaactgac ttcgagcatg aaaacgaaag
    36421 atttccttag ttccttcagc caaatccgcc aaaaatgaaa tcgtaaaata aaagctgttg
    36481 aaggacaagc ctagcaaggt gataaccttg acaaaatcag ctgtctcccc ttcaatcact
    36541 ggaaacggca ttagcaaccg atagcacact aaattatgaa aatctcgctc cccagtcata
    36601 ttagccttaa tcaataaaag atgtattagt aagccagtaa gacatgcttt cattccaaca
    36661 accagcaggt tagataattt catggtgctt cctcaatttt aaaacgatgc acacacccac
    36721 taagcctaaa taaggtgata aaaggtaagg aatatcagca tcactataag atgttgacat
    36781 caaagaagtc ataagaacat atttgggagg taaatagcta tataacaacg gtgacaaagc
    36841 ccacatcaaa atcaaataga gcatgcttga cttaataaag gattgaagat agtcaacaag
    36901 aaaacaaacg aaatacgtat gaacgaacaa agctaacgat tttactaagc aatagtaagc
    36961 tataaaggtt gttgctcctt gaccaaaaaa acgcaatatt gagttttgat caaaataagg
    37021 cattaaatta ccgttcatat gggcaacacc atttagccaa gacactaaag tcaaagcaaa
    37081 tattacaatg taaaaactca gtaaaacata taagctcaac tgaagcttta aaaaaataca
    37141 ccttttacca tagtcagact ttctgccaat gaggtattta agatgtcttg acttaaggta
    37201 atagtaggca taggccacta aaatcatcac tagtggatag ataaaagatt gataaaaact
    37261 aaaatcaaac accacactat ccaaacgtat catactcaac aatagacttt tctttacctc
    37321 aattccacca gataaatcta ctgcacttgt atcaaaaaat aagatatgct tcaaactgtc
    37381 aaaataaata aaacctaaaa atagtaacgg gactaatgga taaaaatagc gaaatggaaa
    37441 taatctatac tgtagcattt atgaataact cccctacaaa aaatcaagga aacgcctcgt
    37501 tactaactca attcacaatt gtagatattt accaattgtc tggagaccaa ctaccactaa
    37561 tggttgttgc tccgtcccac caattttcac gtaccagatg caaggcataa aggtacccac
    37621 ttttagtatc ctgtgtataa attcctctgt cgcctgtcca agttttatct atatcacttc
    37681 ttctttgacc gttactatta gctagatagt gccttaccac aatttctcta ttacgtcctc
    37741 ttgaatctaa attaacgaca taataaggcg ccgcactctt cacaagataa tctttcgtcc
    37801 ttccaaaaga tgacgtgatt ctaaaatttt gcaagtaacc aatttgtcgt tctgctataa
    37861 ctaaagaact aatcaataat gtagaagcta caattgccaa taatccaatc ttaattttgc
    37921 ctaattttat tttttaataa tttataattt ttatatattt agcacatcat cagcgcttcc
    37981 ttgacaattg ataatacaat tcatgctagg cttaatcgat aaaactaaat actagatagt
    38041 aatcaacacc agtaaaccaa gattgtaaac cctttctttt tcgtttatat tttaacatta
    38101 atattatttt tggtcaataa ctatttttgt tttatcataa aaactatata atttatcatt
    38161 aaattaacag aaaaatggtc caaaaatact attctgaacc atttttctta taaattatac
    38221 cttaataagc ttccttaaaa catagacttt cagttggatt attttgataa ataataaatc
    38281 tgtctactgt ttaattctcc agacttttca agtcattaat cccttgtcta gctgagtaac
    38341 cttcatcaaa gtacacacga tcctttattt tctctatttc taacttatac ttatttgaat
    38401 tgaataaagc ctcatattct ttatcaaatt ctaaatagtc attattctta tttttagctt
    38461 ctgatagaat agagctgatt gcataggtgt cagtcaaagc atcaattcta tcagcaaaat
    38521 tctttttctc tttatcacta agcttactca attctttaat actatctttt gcttcattct
    38581 ttctttgatc agaatagtct tctgtaaggg tacgacgtga ataaggattt ttatttctta
    38641 ggcgcaaata tttccatgag tacccacctt gattccaacc ggtataatta tatcttgaac
    38701 tattcgcact tactgttcct gtacttacag ttgctcctgc taatacaagt gctgctgcac
    38761 tggctaaaac taattttttc acgttgaaaa atcctccatt tattaaataa gtttagggtt
    38821 ttattttact attatcttca agcttcttca atatcagttt taatagcgtg ttacaaaaca
    38881 agaataacca ctcatgtaaa cgagtggtta tcagcttttt atagtattgg gctcaaaatt
    38941 ataaggaagg cattttttgc tagggtcttt atttcaccac aatattaacg agcttattag
    39001 gaacaacgat gacctttgcc acttccttgc ctgcaatttc agcctgtatt ttatcatgtg
    39061 ctagggctac tttttctagc tcttctcttg agaggtcttt tgccacgaca agcttagcct
    39121 tgacctttcc tttaatttga acaacgattt caacatcatt ttcaacgagc ttactatcgt
    39181 catgggttgg ccatgcaaca tacgagatgg attgacctga agctgtcagg atctgccata
    39241 attcttcacc taggtgtggg gcaaatgggg ctagcaattg aacgaagcct ttggcgtatg
    39301 ccacataaag ctcgtcctct ttattggctg cattgacaaa aatcatgagc tgggcaatag
    39361 cagtattgaa tttcatgcct tcgatttgtt ctgtgactgc cttaacagtc tcatggtaag
    39421 ccttatctaa agctccgcta ttttctgcaa caatttcctt tgtcgtgatc aaacggtaaa
    39481 cacgatctag gaacttgcgt gctccctcaa ggccttcttc agaccaagca atggacgcat
    39541 caagtggccc cataaacatt tcatacacac gcagggtatc tgctccgtac tgctccacca
    39601 catcgtctgg gttgacaacg tttttcagtg atttagacat cttagcaggg gcctgctcaa
    39661 gctcctcgcc tgtttccatg tggaagaagc taccatcacg cttgtcaacc ttatccgttg
    39721 cgaccaaggc cccacgatgg tcgcgatagc tggttcccaa aatcatgcct tgattaaaga
    39781 gcttttggaa gggctccttg gttggcacta cacccagatc atagagtacc ttgtgccaga
    39841 agcgtgcata aagcagatga agcactgcgt gctcagcacc accaatgtaa atatctactg
    39901 gcagccattg ctttaacagg tccttatcag ctaattgctc atcattgtgt gggtcaatat
    39961 agcgaaggta ataccagctt gagccagccc actgtggcat ggtgttggtc tcacgacgcc
    40021 ctttgacccc atcctcgcgg gtcacctcaa gccagtcagt caagttagct agtggtgatt
    40081 ctcctgtacc agatgggcga atatccttgg tcactggcaa aacaagtggt aggtcctgct
    40141 caggaaccgc tgtcgaggta ccgtcctccc aatgaatgat tgggattggc tcaccccagt
    40201 agcgctgacg actgaacagc cagtcacgta ggcgataaga gaccttttca tgaccgacac
    40261 cagtctcctc cagccacgcc accattttag caatggcaca agccttatca agaccatcta
    40321 ggaagtcaga attaatgtga ataccgtcct ctgtgtaggc agcctcatca acattgcccc
    40381 cttcaagcac tggaataatc tcaagattga attgctttgc aaatgcccag tcacgctcat
    40441 catgcgctgg cactgccatg atagcacctg taccgtagct tgcaagcaca taatccgcaa
    40501 tccagatagg catttctttg ccattgaccg ggttgatcgc ataggctcct gtccagacac
    40561 ctgttttttc cttggcaaga tcggtacgag caaggtcaga tttgaggctc gcttggcgtt
    40621 tgtactcagc aacagcctgc gcttgctctg ctgtagtaat gctatctact aaggcgtgtt
    40681 ctggtgccaa aacagcatag gttgcaccaa acagggtatc aggtcgtgtg gtaaagacgg
    40741 tgaagtcttt atcggtatct ttgaccttga aggttacatt agcccctgtt gatttaccaa
    40801 tccagttgcg ctgcatatcc ttgatcgact ctggccaatc cacttcctcc agatctgcta
    40861 gcaagcgctc tgcgtaggct gtgattttga gcatccattg gcgcatgggc ttacggacaa
    40921 ctggatagcc tccacgctct gatgtgccat cagggagaac ctcctcattc gcaatagctg
    40981 ttcccagctc ttcaacccag ttaacaggca cctcagcttc ataggctagg cctttttcat
    41041 acaattttgt gaaaatccac tgtgtccatt tgtagtaact aggatcagtt gtattgatct
    41101 cacgatccca gtcatacgag aagccaagag cattgatctg acgtttaaag ttggcaatgt
    41161 tttctgctgt aaactcagca gggtcattac cagtatccat cgcgtattgc tcagcaggca
    41221 gaccaaaggc atcccagccc attgggtgga ggacattata accctgtgca cgcttgaagc
    41281 ggcttaaaat atcagttgca gtgtaaccct caggatgccc aacatgaaga cctgcaccgg
    41341 aaggataagg aaacatatct aaagcataaa atttaggctt tgaggcatct gtccccgttt
    41401 taaaggtatg attatcagcc caaaaggcct gccacttagg ctcaatggct ttgtgattgt
    41461 aaaatgtcat gtgaattctc ccatgtaaaa agtctagtct tcttattata gcacgatatc
    41521 agacttttag gaatgggcaa gcaatattgc tgccacgacg tcggcatcac aaaaatgcat
    41581 gtaaccattt tctagctgca tgcatttttt taatctatgt tcagcggttt tgcattgcaa
    41641 tatcaccagt ttctcgattg ctatttgact atttcataac atattgccaa aaaaactata
    41701 ctgatgataa aaactcgcta tgagaaagtg taactgtctt catgcgtttg tcacgacatt
    41761 gctaaagccc tttagactag atagcgcgtc tctgcgacgc ataagctcaa gccttacgag
    41821 ccaactcata aaacagccaa atatccgcta tcatctcact tggttttaga tctggtctag
    41881 ctctagtttt aagctctcaa agaggtattg agcttgacca aggagtgctt gctaagctac
    41941 taaaaagccc cttatccttg ctatcagata agaagctcaa tagagtttat aggaatgcca
    42001 atgtccatta gtaaaatgct ataaaacaat agttaaaggg gagagaattg agaatagctt
    42061 aatttttttg gcgttttggc atgactgtta ctaggcctgc acttgtcata atcgcaactg
    42121 cagcagcagt gaaaaatgga tttgcagtag cttcacctgt tgatggtagc tggcctgctg
    42181 gttttgcggc tggcttactt gctttttgct ttgcaaccga gttcgatgcc tgaggagtct
    42241 tagaacgagg ctgtgcctga tccttaaact tgtcagcaag ctcctgcttc aagcgctcaa
    42301 tgttagcttg aagatcagca ttgctacgat ccttttgctc aagcaggctt tgaagctcct
    42361 taaccttagc ctcaagctct gccttgtctg ccttaaccac atcaagctcg gctgtttttt
    42421 cagctaattg cgcttcaagg tcagccactc tattattagc tgctgctacc tcttgcccaa
    42481 gatttgatac tcttgcatta gcttcagcaa gtgcctgatc tgccgcagct ttttcctttg
    42541 caagcttatc aacattagcc ttagcacctg ccagctcctc ttgaagtgtt gtgatgttag
    42601 cattagcagt ttcaaggtca gtctctgctt taaccttgtc ctgtgttaat tgatcaatct
    42661 cagcaagctt ctctgtgagc tcacgcttag cagagttagt caatcgaccc agactatcaa
    42721 cagcctgact taaacgatct gcttctgctt gagctactga gagtttgttg gcaagatcgg
    42781 cagattcact gagagcatta tcacgatctg atgttacctc ttccagttta gtgcttaatt
    42841 ctttagaagt aagtttttct ctttctatat cggctttcaa ttgagttgtt tctgctttca
    42901 aagtagcttc agagtcgatg cgagtcttta aattcgctaa aagttttgag gaaataaaat
    42961 tacttccttt gataccaata gaagaattaa tctttttatc taaactaggg ttgatttaca
    43021 actcttcatg ttgtttgttt ctccttttta tttttctctt tcccagacca aagcacctac
    43081 tccctaaggg aattacacgt tggcctatag ctatattcta cctaatttta ttggattaac
    43141 aaagctcact aattttacac catgacaagt tgtggctatt ttaatgaaat ataccgatat
    43201 ctatcaatag ccgatgttcc caagcttgtt agttgttttc gtttcaaaga tactacccat
    43261 tcgttttctt agataatggt taagcttggc gactataacg gttggcacaa atcgactaaa
    43321 gaaaaagata tcagcatgct cacagcccct aatgaccgta tcagtaataa tgacgtcata
    43381 gtcatgctgt agacacaagg cttctatggt taatttatca aaaatggtaa tctcaaaaaa
    43441 ttcaccaatg tattttttca aaaagcttcc cgtactgcca tgacttcttt ctataatcaa
    43501 gagctttggt tttttcatca attcacacat ggttaaaaag aaattctccc aggctatcag
    43561 caaggaataa accaaattgt tgagcaaatt agtagcaagc tccatatccc cgtccttaaa
    43621 tagcctcttc acataatcgg taaacctaaa ataaacatag gtataatgct ccttaaagaa
    43681 ggccaagtaa tcctttttat aatcgtaaat cagaaagctt tcactaatat cctccactcc
    43741 taaaataaca gtggcatgaa gatatctggc aacctcatat ttatttggca atacaatacc
    43801 tgtagctccc tccatttcac taagcaaatc tatccagctc agcaaggact gaggacccgg
    43861 aacctcctcc ttaaccttat ctacctgcaa ggatttttct aataccaaat catcatctaa
    43921 ataattggaa aacatttctg acaagacaag ctcatcaagc ggtactgaaa atttaagcac
    43981 aaacaaatgc gacagctttt tcatctcctg agaatcctgt aacaactcca atgaaagact
    44041 actcagtgct ttatgcttcc caattttaaa gcctttgagg tagcgaatga gattaaccgc
    44101 acttaatagc ttgagttgac gaaaaatcgc aaaatcaatc ttaacctcta tcaaagatgc
    44161 cattaattga acaaattgct catggtggtt ttcattaagt agagaagcaa aaggccattc
    44221 agaaaaggta tatgcttctg aaaaatactt gatgtaaaac agtctaatat tgtattcatc
    44281 tccaactaca cgaatgggct tagccgaaat gataatatca aaatgctctt ttaaatagag
    44341 attggtttta cgaatcaagc gctttaaggt tgacaagcta ataaaaagtg cctctgcaag
    44401 atcatctaat gacgcaaaat catcaaaaaa caaggccgac atcaactgaa gagaaggaga
    44461 ctctagcaag gctctccgat aaacctcctt taagccactt tgatgattgt aatgaatatg
    44521 aaattgagaa tccttgtaga acagcttgcc taaatcttcc ataaaaacag aattcgtgat
    44581 acacgattgc agcgttaaaa ccgaacaatc cagcatctga caagcatctt tataatataa
    44641 tggatttttc gtttcactta ataaagtaat caactcaagc tctcgccact gctgcttggt
    44701 aaagagattc tctatagaca tggtatctag ctcctaaata tactcttcct gattaaaaac
    44761 ttaccacaac acaacactat ttcattaact cttaatgtcg gttgtagaac agtattacat
    44821 tatagcatac tattagccag aaatacctta gaattgtttg caaattaacc gattacaaat
    44881 agacaaaagc ctttaaaaca caacagtcaa ctcatttttt tattacatta taaattgtag
    44941 acttttttta ttttctctta ttttttagct ctgccat
//
LOCUS       DARYMD010000013        43743 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYMD010000013 DARYMD010000000
VERSION     DARYMD010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43743
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(19..1290)
                     /locus_tag="TU818_000630"
     CDS             complement(19..1290)
                     /locus_tag="TU818_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL0923473.1"
                     /translation="MPDNLAIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLASMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTGNPFFSVTPAIRSRVQIFELEPLSPEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDTEGIRHISL
                     NTVENSLQRSYITMDKDGDGHYDILSALQKSIRGSDVNASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYAGSKELGNAQHYLYPHAYPEKWVKQQYLPDHL
                     VKKNYFNPNETGKYERALAANKARIDKLSSS"
     gene            complement(1283..1891)
                     /locus_tag="TU818_000631"
     CDS             complement(1283..1891)
                     /locus_tag="TU818_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL0923474.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDFEDNEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TU818_000632"
     CDS             complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TU818_000632"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL0923475.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     DLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDSCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMRQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGMLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESCWQDEFEEIKQKSSFLNRQSIDFTIKTTAKVEQQSLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTDQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELKLSDLDKAEAIFGGNAVRGL
                     YSLTIEDTTLPQ"
     gene            3817..4287
                     /locus_tag="TU818_000633"
     CDS             3817..4287
                     /locus_tag="TU818_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL0923476.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKLDFSLEWNEEAFEEGQVGLEETELYSYPRY"
     gene            4289..4633
                     /locus_tag="TU818_000634"
     CDS             4289..4633
                     /locus_tag="TU818_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL0923477.1"
                     /translation="MLHEMMLTPRPFAMIEAGVKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSHILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            4650..5078
                     /locus_tag="TU818_000635"
     CDS             4650..5078
                     /locus_tag="TU818_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0923478.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(5276..7813)
                     /locus_tag="TU818_000636"
     CDS             complement(5276..7813)
                     /locus_tag="TU818_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0923479.1"
                     /translation="MKQHQRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKATK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPASNQAARSGSVVSTGHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATINHIASTTPHFPSTPPSIHQQGGIPGIDFKTSDGFLFDG
                     TNISGVTDTGILVKHGNHLHPISFEDLKRSKWAYLVEQYKKKDHTKPQEGDYRAYIAY
                     LAKELKVDQARIKQVNVDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRDGVYKKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNDVTGNSNHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            8376..9329
                     /locus_tag="TU818_000637"
     CDS             8376..9329
                     /locus_tag="TU818_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL0923480.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELTLTNQEL
                     AEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKSEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            9329..10075
                     /locus_tag="TU818_000638"
     CDS             9329..10075
                     /locus_tag="TU818_000638"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL0923481.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDKEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELAGLSPGQKVLFIFGPEGGISSKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALELMSS"
     gene            10324..11328
                     /locus_tag="TU818_000639"
     CDS             10324..11328
                     /locus_tag="TU818_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0923482.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            11625..13811
                     /locus_tag="TU818_000640"
     CDS             11625..13811
                     /locus_tag="TU818_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL0923483.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPML
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADILENDDTKPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGIQAVYGPKADILKSDIQDLLDSGAVIPEPKPAQPA
                     ASSSQQTDFKNLTEAVLAVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLTAITAAGRKTTVVVAFTNTTSIKAVNLVATGQQKAKTLVAQVEL"
     gene            13889..14710
                     /locus_tag="TU818_000641"
     CDS             13889..14710
                     /locus_tag="TU818_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL0923484.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAAVSLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDGREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVVSDHYGLEVDLSWKL"
     gene            complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TU818_000642"
     CDS             complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TU818_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL0923485.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFSVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(15860..17044)
                     /gene="sezV"
                     /locus_tag="TU818_000643"
     CDS             complement(15860..17044)
                     /gene="sezV"
                     /locus_tag="TU818_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
                     /protein_id="HEL0923486.1"
                     /translation="MDTMSLVKSLQGCLKLSITVFDKDHQVTESFWNDDTFEFYYRFQ
                     AVLRQMDKEQATNLFFQGSYNELFLIYRYQDHYILIGPWRCNVLDKTFFKVAVADKDL
                     TKEEEEILYQALKHLPVYPLNAIRDLLIVVHYFFSGKIEDLLSPPLRHYIRDFSDNIE
                     VQKANMFVKKQESKVCLYNYEKNLSSIVQEGDVHKLKEIIFSLRNTFIPVVSGDTLRS
                     EKNYSIIAFDRLAQIAIQSGMDIADAYHSREEFMRDSELATSMPDVLKIRDASLVFYT
                     QKVSELRDNRWKHVSPTVNAIIQYISVNLHKSVTTAELAQHFNMSESKLRQIFKRDTG
                     LTIYQYTSNMKIEEAKTLLRSAYAINHISDVLGFTDPSHFSKFFKKHTGESPKTYQNR
                     KH"
     gene            17294..18898
                     /locus_tag="TU818_000644"
     CDS             17294..18898
                     /locus_tag="TU818_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL0923487.1"
                     /translation="MFLRNNKQKFSIRKLSAGAASVLVATSVLGGTTVKANSEVSRTA
                     TPRLSRDLKNRLSDIAISGDASSAQKVRNLLKGASVGDLQALLRGLDSARAAYGRDDY
                     YNLLMHLSSMLNDKPDGDRRQLSLASLLVDEIEKRIADGDRYAKLLEAKLAAIKSQQE
                     MLRERDSQLRNLEKEKEQELQKAKDERQALTESFNKTLSRSTKEYNKLKTELAKEKEK
                     AAKMTKELADKLSNAEASRDKAFAVSKDLADKLSSAEASRDKAFAVSKDLADKLAAKT
                     AEAEKLMENVGSLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTE
                     LEKAKTELAVSERLIESGKREIAELQKQKDASDKALVESQANVAELEKQKAASDAKVA
                     ELEKEVEAAKAEVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEM
                     LEKKDHANADLQAEINRLKQELADRIKSLSQGGRASQTNPGTTTAKAGQLPSTGESAN
                     PFFTIAALTVIAGAGMAVVSPKRKEN"
     gene            19121..21340
                     /locus_tag="TU818_000645"
     CDS             19121..21340
                     /locus_tag="TU818_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL0923488.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVVCGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAVHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTERERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDVIEGYITKG
                     RGIAIHRADCNNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            21355..21798
                     /locus_tag="TU818_000646"
     CDS             21355..21798
                     /locus_tag="TU818_000646"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL0923489.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNAQLEQLVPVQRGVFGADMQVSLINDGPVTIILDTKYR"
     gene            complement(21925..23217)
                     /locus_tag="TU818_000647"
     CDS             complement(21925..23217)
                     /locus_tag="TU818_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL0923490.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKVSKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIIDSNRIAQVYNSKYDVNNPISYAT
                     HSDSVVETYFISKDINDDYSTTYRSVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KGLPNTFQAKNGTSYQFTGSLTPISETEFIAVYKDLQK"
     gene            23972..24820
                     /locus_tag="TU818_000648"
     CDS             23972..24820
                     /locus_tag="TU818_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL0923491.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVGEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLANLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAY
                     LFILKH"
     gene            24970..26103
                     /gene="ugpC"
                     /locus_tag="TU818_000649"
     CDS             24970..26103
                     /gene="ugpC"
                     /locus_tag="TU818_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL0923492.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            26287..27906
                     /locus_tag="TU818_000650"
     CDS             26287..27906
                     /locus_tag="TU818_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL0923493.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIAAIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLMSIFSGSAWEYDDASGQYYLHIFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNASKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDC
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLETSDKVFAYKRQLGRETYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDETL"
     gene            28015..28377
                     /gene="traF"
                     /locus_tag="TU818_000651"
                     /pseudo
     CDS             28015..28377
                     /gene="traF"
                     /locus_tag="TU818_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
     gene            28491..28850
                     /gene="yajC"
                     /locus_tag="TU818_000652"
     CDS             28491..28850
                     /gene="yajC"
                     /locus_tag="TU818_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL0923494.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTETAVD
                     DTAVEASDEAESAIETN"
     gene            29024..29773
                     /locus_tag="TU818_000653"
     CDS             29024..29773
                     /locus_tag="TU818_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL0923495.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            29783..30577
                     /locus_tag="TU818_000654"
     CDS             29783..30577
                     /locus_tag="TU818_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL0923496.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGIVISSDSY
                     GFEDASFPIAASLYVGIGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            30609..31874
                     /gene="rseP"
                     /locus_tag="TU818_000655"
     CDS             30609..31874
                     /gene="rseP"
                     /locus_tag="TU818_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL0923497.1"
                     /translation="MLGIITFIIIFGILVLVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQS
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDEIKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            32144..34000
                     /locus_tag="TU818_000656"
     CDS             32144..34000
                     /locus_tag="TU818_000656"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL0923498.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            34052..34609
                     /locus_tag="TU818_000657"
     CDS             34052..34609
                     /locus_tag="TU818_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL0923499.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLPLKDCWLAAGAIRNAIWN
                     HLAYGIGFDPLTDVDVVFFDPEISYEAEQLLEEQLKCAYPMYQWEVRNQAYMAAHNPK
                     TPPYRSSQDAITKYPERCTAIAVRLVGGQLEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHDC"
     gene            34944..39341
                     /locus_tag="TU818_000658"
     CDS             34944..39341
                     /locus_tag="TU818_000658"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL0923500.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFETNRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEDAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEKVEVVKDDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQQSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            39463..39891
                     /locus_tag="TU818_000659"
     CDS             39463..39891
                     /locus_tag="TU818_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL0923501.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            40021..40566
                     /locus_tag="TU818_000660"
     CDS             40021..40566
                     /locus_tag="TU818_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL0923502.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGKAAVSYLDWEQVPM
                     FSQDLEASTPESVAGVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIH"
     gene            complement(40745..41359)
                     /locus_tag="TU818_000661"
     CDS             complement(40745..41359)
                     /locus_tag="TU818_000661"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL0923503.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILN"
     gene            41724..43151
                     /locus_tag="TU818_000662"
     CDS             41724..43151
                     /locus_tag="TU818_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL0923504.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKEITQPSHLIVYDKYDGKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGMSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEKPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKG
                     VLALVGVGILAMLGLGFWFRPYQKD"
     gene            43417..43686
                     /gene="rpsO"
                     /locus_tag="TU818_000663"
     CDS             43417..43686
                     /gene="rpsO"
                     /locus_tag="TU818_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL0923505.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
BASE COUNT        12326 a         8697 c        10417 g        12303 t
ORIGIN      
        1 cttgtttttt tctttaggct agctgctaga aagcttatca attcgcgctt tattggcggc
       61 taaggctctt tcatattttc ctgtttcatt tgggttgaag taatttttct taaccaagtg
      121 atcagggaga tattgctgct tgacccattt ttctggatat gcatgagggt aaaggtagtg
      181 ctgagcattg cctagctcct tgctgccggc ataatgccca tcacgcaggt gtctaggaat
      241 gggaagatgg ccatgttgac gtaaatcagc gagagcagcg tccatagcca tataggcgga
      301 attggacttt ggtgacagtg ctagatcaat cacaacattg gcaatgagga tacgcgcctc
      361 tgggaagcca attttctggg cggcctcaag tgcagtgacg gtatggattt gagcttctgg
      421 attggcaaga cctatgtcct cataggcgat aatggtcaag cgtctagcaa gactcggaag
      481 atcgcctgcc tcaataagcc ttgcagcata gtgcaagcta gcattaacat cagatcctcg
      541 gattgatttt tgcaaggcag atagtatgtc ataatgtccg tcgccatctt tgtccattgt
      601 gatgtagctg cgctgcaaag aattttcaac agtattcaag ctgatatgac ggataccctc
      661 ggtatctggc tgggttgaca tgacagctag atcaagggat tggtaggcgg ctcggagatc
      721 tccatttgtc gctgtcgcaa taaagtcaaa agcagcctca tctagggtca catcaaaggc
      781 aaagcctctc tccttatcag tgatggcaag cttaagcgcc tgcttgatct cctcaggtga
      841 taggggctcc agctcaaaaa tctggactcg acttctgatg gctggagtaa ccgagaaaaa
      901 aggattccct gtggtagcac caatcataat aatgtgccca tgctctaaaa gtggtagtaa
      961 aaagtcctgc ttactcttat ccaatcggtg aatttcatca agcaaaagca caagtccacc
     1021 tgaaaactta gcttcctcag cgatttcttg gaggcgtttt ttattgtcta tggtagcatt
     1081 gaaggttcta aaggcgtact tggttgttcc agcaatagca ctagcaattg atgtctttcc
     1141 aataccggga ggtccgtaaa gaatcattga ggctaatcta ttggccttga ccatgcggtc
     1201 aatgattttt ccctccccga ccagatgctg ctggccgatg acctctgtaa tggttctagg
     1261 gcgcattctg atggctagat tatcaggcat tgtattcctc ccttccttgc ttttgttggc
     1321 tgtggtgctt tttaacaaca gccataaagt ttgcgatcat tgtcctaccg tcagctgttc
     1381 cgatgctttc tgggtgaaat tgaaggccaa acagtggcag ctgtctgtgt tcaaaggcca
     1441 taatctcatt gtcctcaaag tctcttgcgg taattacaaa gtcagctggc aggtcatcaa
     1501 caacaataga atggtaacgc atgacggtta attgctttgg cagctgttga aagagcttag
     1561 ctggtgcttg tctttcaagt atactttgct tgccatgcat gacgcgctta gcaaggcgta
     1621 gcctgccacc tagagcctca gcgatagctt ggtggccaag gcaaacgcca agcataggct
     1681 tttggtcata aaaggcccta atcaagctag gcatctgatt ggcggctttg ggccagccgg
     1741 gtccaggtga gaggactatg gcgtcagcct gcttcgcaag gtcaaatagt tttggatcct
     1801 gattggtcaa tacaatcgtt tgatcaaagg cactgaggta ttgggccaga ttataggtaa
     1861 atgaatcgta gttatcaatt aaaagtatca taaggtcctt catctagtag tgctgaggga
     1921 tcagcctggt actattgagg cagagtggtg tcctcaattg ttagtgagta gagtcctcgg
     1981 acagcattgc caccaaaaat ggcttcggcc ttgtctaaat ctgaaagctt tagctctttt
     2041 tcctgagcca gtccctgcct tagtaattct tgacggaaaa tgcctggtag aataccggct
     2101 gatacaggcg gtgtataaag ggtctgctcg atttgcacaa aaagattacc aatagaggtt
     2161 tcaagcaagg tcccatcagc agcaacaaag acttgctcat aaggcttgac gctcagatgt
     2221 ggtcgatgac tggttttaaa ataagtaaag ggaagctttt tgacatcgct tgattggcga
     2281 actaatcgtg cctttaaaaa gtctttttga agcggctcta agctttggtc tgtaaggcta
     2341 atctgcccgt ccttagcaat agcaatagtg agacgatagg ggctgctgtc ctttcccttg
     2401 agataggctt gcaaacgatc tgtcagaagc tcttcgtcat aggggtaggc aaaataacgc
     2461 gccgcctccc ttagtctgtt gaggtgctgg tctagatata ttaggctttg ttgttcgacc
     2521 ttggcagtgg ttttgatggt gaaatcaatg ctttgacggt tcagaaagga agatttttgc
     2581 ttgatttctt caaattcgtc ctgccagcag ctttcccagg taatcccacc gcctaccccg
     2641 tagatggcct gatcgtagct gagctgaatc gttcgaatag cgacattgaa gacacgtctg
     2701 ccatcaggca ggcaaatacc aatgctgcca cagtaaacgc cccttggctt aggctctaat
     2761 cggttaataa tagccattgt agacacctta ggagctcctg tgatggagcc acagggaaag
     2821 agtgcctgta aaatatcata aagacgacac tgatcctgca gcatgccgac aatggtagag
     2881 gtcatctgcc aaacggtgga atattgctcc aattggcaga gctgtgtgac tgtgacactc
     2941 ccagtttgac agatcttatt catatcattg cgtaataaat caacgatcat catgttttct
     3001 gaacggttct taggatcggc ctgtagccag tcatgctctt gttgatctag ttctaaattg
     3061 taaccacgct tggttgtgcc tttcatgggg cgtgtggtga tctggttttt ctcttgcttg
     3121 aaaaataact caggactggc tgaaatgaca gcaaagtcat cgtgagcaat gtaggcattg
     3181 tatccagctg cctgttcaat gaccaattga tgataaatgg ccaagctgtc cttagcgttt
     3241 agcctttggc tgagctgaat ggtatagttg acctgatagg tattgccctg cctcatctcc
     3301 tgatgaatct gtgcaatagc ctcttgatag gcttcctctt gtgtagcact tgtccagctg
     3361 tttggaatcg tcatgctgtc gtggtagagc ggaaagtcct cgagctgaca gctgtcatgc
     3421 actgtaaaat aagcaaaata ttcctgacca agtcttttat tgtgtgttgt tagctttttg
     3481 tcaaaacagg ctgctgcttc atagctgagg tagcccacaa catagtagcc cagatcttga
     3541 aattggttga cctgctcaag gacctgtccc acctgatcaa tctgcttagc tactaattcc
     3601 acgataggag cttgaaatat atagcgttgt cccagctcct taaaatcaat aatcgtcttt
     3661 atatgcatag cttgattata tcataaatgc gcttttcaga ctgattagga gggttgaaaa
     3721 gaagcctgtt agcaaccatc aacaatacaa gagagcaggg cttcttgatt tatgctacaa
     3781 tagtagcgga tattatttag aaaaaggaac aagagcatgg ctaaatatgg ctttttatca
     3841 gtattagaag aagagatgga caagcatttt cattatgact atgctatgga ttgggacaag
     3901 aaaaatcatg cggttgaaat cacccttgtt ttagaggctc aaaatcagtc agcagttgaa
     3961 accattgatg accaaggaca gctcagcaag gaagacattg tctttgagga ttatgtctta
     4021 ttttacaatc cggagaaatc acagtttcaa gcagcagact atctggtggc tattccattt
     4081 gagccaaaaa agggcttttc tcgtgaattt ttagcctatt ttgcccagtt tctcaatgat
     4141 gttgccattg aagggcatag cgatttgatg gatttcttag cagatgatag caagcttgat
     4201 tttagtctag agtggaacga ggaggccttt gaggaagggc aggtaggact agaggaaaca
     4261 gagctttata gctatccgag gtattaagat gctacatgag atgatgctga caccaagacc
     4321 atttgctatg attgaggcgg gtgtgaagac tattgaacta cggttaaatg atgagaaaag
     4381 gcaggctatt aaggtagggg attggatttg cttttattgt acagaggatc atagccatat
     4441 tctgcaagca gaggtcgtag ggttgcatta ttttgatgac tttgctaagc tttaccaagc
     4501 attgccttta gaaaaatgtg gttatcgtaa tgaagaattg gcactggctc ggccggagga
     4561 tatggaacag tactacagca aagagcagca agcccaatat ggcgttgttg gtattgagct
     4621 aaggctatgt tgattggtga gatctagtca tgaagctttt agataaaaca gtccattttt
     4681 ctggtgcaaa gttagccttg atcagtaacg gtaagatttt gaccatcttg cgtgacgcga
     4741 taccaacgat tccttaccct aatatgtggg atttaccagg aggtggtcgt gaaaatgctg
     4801 aagctccctt tgattgtgcg tcacgtgagt gctatgagga gttaggtctg gcactgacta
     4861 aggacgctgt cgtttgggaa agggtttatc cagggcttgt taatcctgac agccaatctg
     4921 tctttctggt ggctcttatg aatcaggaca tgatagatca tattgctttt ggtgatgagg
     4981 ggcagggtta tcagctgatg gctattgatg actttttagc agacgatcgg gtcattcctc
     5041 agctaaaggc tcgcttagct gattatttaa ggaaataggc agacttagct ggtacactaa
     5101 acagatcagc aaacaccact actatgtgat agctacgacc agaatcaaaa agacgattga
     5161 cctctgccca catgtggcta ggatcaatcg tctttgtttt tggggtggct aagtctttaa
     5221 tctggtaggc cagatcagct gagtagttga tattatcaat cagtcctgct atggcttagc
     5281 tgttgctagc tactgatgtg ctgctagctg tctctgactc acctaaaaaa tagctggctg
     5341 gcttatcact tactggcgtc ttaccaacaa gctcagggtc aggtgctaat aggtcgtcct
     5401 cgtcggagtc agaaacgggc gctacaaatt cttctagcca gcttccagtg ctgccagtgt
     5461 gattaggagt ttgaggctcc ttaggtagtg gatcacctgg tagccaggta ttccctgagt
     5521 gattactatt acctgtaaca tcgttgttgg ttattttatc aaagttgacg ttataaacaa
     5581 tatcctcagt gacttcctta tcatattcct cagttgaaat aataggctta ttgtaatcac
     5641 gcttgtagcc ggcatctggc tgtactgatg gtggtaggat accagctgta tgtaatgagt
     5701 gtcccttacg aacaaggtaa acggcagtct tacccttacc agctcggcta atcagctgtc
     5761 cgccctctcc tgccttaaag gcaacggcta catagtgtct cggatcgtgg aagtaataat
     5821 tagggtgtct gctaggatcc tctagatcag ttggcttgtc aggattaaca gcgatgtaag
     5881 gtccaatata aggagcagta gttccaaagg ctgctgagaa taggccagta aaggctacct
     5941 tatcgttttc attttgtgtg atagaaaatc tcttagcaaa atcagttaga ttaaagttat
     6001 tggcaaggtt cactccactg cggtattcaa taaattcata gcctggatct gggacgggct
     6061 cagggataac aagtccttgc tccttagctt ccttccaggt aagaccacta cgaacattgt
     6121 agaagaagcc tccttgagtc acgccgttaa gcttcaatcg cccattaaag attgtggtga
     6181 accagacagg aacataattt tctaagtcaa ggtctgaaac atcatcacct ggcccgtaga
     6241 cagccttggt aggctgcttt ctaaccttat caaaatctac atagaagcgt tgatgttctc
     6301 tgtccatctt gccagctgtt ggcaactcag cactccagcc cttaaagata cgcccctcat
     6361 gcttgattgc ctctggacgc tgaatgttca aatccttcca gtccaaatcc ttacgaacca
     6421 aatagtgcac acgtttagtt ttaatgccat taacctcaat gtcgccgtat tcactatttg
     6481 tactaaacaa cacatggata aagtttttga tgtttttgat gccctctggg tgatattttt
     6541 tatagacccc atcacgtgtt agattttcag atgaattttc cgtatagaaa ggaccataaa
     6601 cgagctgagt ttcgacctct agattggttg attctgtctt gacattgcgc tcaggatcat
     6661 ctggcaattc tgggtcaatc ttatagatgt gagcatggtc cccatgacta atggtcatgt
     6721 agttgccctc aattgagatg tcctcacgac gaaccttgaa gcgatccata aattctttga
     6781 tgagtctttc tttgcgctgt tcaaaggttt ctccgtctat ctttttgagg atctgttctt
     6841 ctggagtttt aaatggctta gaaagatcaa tatcctttag ccagatgacg tgcgtgtggt
     6901 cctcatgagg gtattcaaag ccgacctgac cgtctacatt cacctgctta atgcgtgctt
     6961 gatctacctt tagctccttg gcgagataag ctatataggc gcgatagtct ccttcctgag
     7021 gcttggtgtg gtcctttttc ttatattgct ccactaaata agcccatttg ctacgcttta
     7081 agtcctcaaa gctaataggg tgcaaatggt tcccatgctt caccaggatt ccagtgtcag
     7141 tgacaccgct aatgttggtg ccatcaaata agaagccatc actagttttg aagtcaattc
     7201 ctgggatacc cccctgctga tgaatgctag gtggtgttga tgggaagtga ggtgtggttg
     7261 atgcgatgtg gttgatggtt gctgatggca ggcttgattt gaggatatag tggtaatgat
     7321 ctccatgacg aacagtgtag ccataggcgt cctcagcaac aatgtcagct ggattaaaga
     7381 catagccgtc tccagcatga ccagttgaga ctactgatcc agaccttgcc gcttggttag
     7441 aagcaggctg tgcttccttg taatccttag gaatcaggta agcccatttt gtccccttca
     7501 aatctgagta aaagaagaaa tgcttgtgat cgccatgctt cacaatgata cctgtatctg
     7561 ttttgcgttc aatttgcgat tcgctggtca ataaaaagcc atcatcagtt gggacatcaa
     7621 tcccagggac ttggtgacgt tctctttttt tcgcagtctt actgcttttt tgttttttct
     7681 ttttcgtagc cttttggtgc tttttaggct cctgagaatg tcccttttgc gaatgcgttt
     7741 ggcaggctgt taaggcaagg ttgcaggcta acagcagtcc aacgagggat aaaaatcgtt
     7801 gatgttgttt catggttagt tatcaactcc ttccaacaat taacttaacc agttaatatt
     7861 attactggtt aagtatatca tttgacatct aagaatacaa tagattttat aaatttttta
     7921 atgaaattaa tctaatgacc taagagctgt ctggaagatg aaaggctttt tagctatttc
     7981 aaaggcttgg agcttcaaca ggcgaatcag ctattggttt ttctggattt acgagaaaga
     8041 gctgctcttt tttgatgtag ctggtataaa atatggtaaa atagggtcta tcaagagcct
     8101 atctaccttt agattggctg agatttgtta ggcaatgcgt ccctgataaa ggttgggctt
     8161 atgggacaat aggccttggt gctgtgtttg tccttagtat gaaacctctg agacggcaga
     8221 gcaggatccg gttggtttag gaccgcatta gcttatctta cgataaaaaa gaagcttgaa
     8281 aggaaaggct gctttgatct gatagagggt cactggtttt agggtttagg ctaggggcaa
     8341 gtgaccactg atgatatggc agcaagggta tcgttatgaa ggcatggcaa gagctgacaa
     8401 ttacagtcca tcgtgaggca gaagaagctg tttccaatct gctgattgag gctggcagcc
     8461 aaggagtcgc tatcaatgac actgcagact atatcggtca agaggaccgt tttggggagc
     8521 tttatccagc tgttgagcag tcagaaatgg ttactattac agcctattat ccaagctcag
     8581 ctgatattga tgacatcaga cagaccatta atcagggctt gaacaggcta aagcagtgtg
     8641 atgtggagct tggtgagtta accctgacca atcaagaatt ggctgaagag gattgggcgg
     8701 acaactggaa agcctattat gagcctgctc gtatcacgca tgatttgacg atagtcccca
     8761 gttggacaga ttatgaagcc acagcaggtg agaagatcat taggcttgat ccgggtatgg
     8821 catttggaac aggcacacac ccaacaacta agctaagcct gtttgccttg gagcaggtgc
     8881 ttcgtggtgg tgagacagtt attgatgtgg ggacaggctc aggtgtgcta tcgattgcta
     8941 gctctctgct tggcgccaaa gaggtctttg cttatgattt agatgatgtg gcggtgcgtg
     9001 ttgccaaaga caacattgcc ctcaatcaag ccactgacaa tatccatgta gcagctggag
     9061 acctgctaaa aggccttact caagaggcag acgttattgt cgccaatatc ttggcggata
     9121 ttttggtgca tgtgacagca gatgcttacc gtcttatcaa gtctgagggg tatctgatca
     9181 tgtcagggat tatttcagaa aagctggata tggtgaagca ggctgctctt aatgcaggct
     9241 tcttgctaga gactcacatg cttcagggcg agtggaatgc tcttattttc aaaaaaacag
     9301 atgatttatc aggagtgatt ggtggctgat gcagcagtat tttattaaag gcagggcaga
     9361 aaaaatcgtt cagctgaccg ataaggatac cattaagcat atgtttcaag tgatgcgctt
     9421 gacggataag gaagagctgg tgctagtctt tgatgacggc attaaacgct tggcaagggt
     9481 gtcagacagc tcagcctatg aggtggagct tatcaaagag ctggaagaaa accttgaaat
     9541 gcctgttgag gtgactattg cctcaggctt tcccaagggt gataagctag atgttatcac
     9601 tcaaaaggcg actgagttag gggcagcagc tatttggggc tttccagcag actggtcggt
     9661 ggtcaagtgg gatagcaaga agctagctaa aaagcaagaa aaattagcta aaattgctct
     9721 tggagcagca gagcaatcca agcgtaatcg cgtaccggag attcaactat ttgaccaaaa
     9781 gggtgagcta ttaaagcagc ttaagcagtt tgataagtgc tttatcgctt atgaggaagc
     9841 agctaaggca ggtgaaaggt cgacattggc gcgtgagcta gcaggtctta gcccaggtca
     9901 aaaagtcctc tttatctttg gaccagaggg tggtatttct tcaaaagagc tggctagctt
     9961 taagcaagca ggtgctatta ctgtgggact ggggcctcgt atcatgcgga cagaaacagc
    10021 accgctctat gccttgagtg ctgttagcta tgctctggag ctaatgtcta gctgatagtg
    10081 ctaataggag acagcacctt gtggctcagt gcttgacaga aaaaagagga gcatctgcga
    10141 ttatgctaat aaagcaccgc ttaacaaaaa gatcgctaag aaggagactg ccgcaaatca
    10201 aagggctagt ctagcccgcg taggtgcaga gctgtcgggc ctttgcagct tcatttgtaa
    10261 aaaatataac aaatcatctc aaaataaaga tactcgtcaa acggattggt agaggaggga
    10321 catgtggtta cgataaaaga tgtggcaagg ctagcaggag tttcgccttc aacagcttcg
    10381 cgtgccatca atgacagtga catgattagt caggcgacaa aggagcgtgt caaaaaagcc
    10441 atggaggcct tggattattc gcctaattat tcggcgcaaa accttgttaa gcgaaagtcc
    10501 aatactgtcg ggatcatttt gccggtgcgt gagggtcagg attcactggg aaataaccct
    10561 tttttcatgc agattattca aggaattgct gctgtttgta ccgatcaggg ctacatggta
    10621 gcccttgcga ctggacgtag tgaggccgaa ttgctaaaaa acgtgcaaaa catgatccgt
    10681 agtggcaata ttggcaagct gatttttctt tattccaaaa cagatgatca ggtttttgac
    10741 tttgtcaaaa ggcaaagagt ggattgtgtt gtcgttgggc aatcaacgac aaaggatcct
    10801 ggcaatgcta aatttgtcaa caacaataac catcaagccg gctatgatgc agcagcattt
    10861 ctccttcaaa aaggctatga ggctattgtc tatgcttata ctgacatggc cgaattggtg
    10921 caggcagagc gttataaggg ctatgcagag ctgatgactt caaaggctct ggcagctcaa
    10981 gccctttgtg tcacgctaaa ggacgatagg aaaagtcaaa agcagctgtt agaccaatta
    11041 gccaagcgct ctaaagttgc ctttgtagtc tgtgatgatg tgctagctat tcatttgcag
    11101 cgtctcatca agcaagtagc agctgacacc cagctagcaa tcgttagctt caataattct
    11161 gtcctagcgg agcttgcgag tcctgccttg acctccattg ctatttttcc ctatcagctg
    11221 ggagagcaag ctgctgagct ggtcttatca agcgcagcgc catcaccaca gccagtctta
    11281 gttcctcatc agatcattga aagagagtct acgcctttta ttgtttgatt taccgttaag
    11341 cctattccta agcaaagtac tgatagcttg cttaggaata aggcttttta tttaggaatt
    11401 tattttgttt gctaatagta ttaaagagaa gcaacgttta ctttagcatt ttcattgaaa
    11461 tcttcttaag aaaacgcttt acaaaacaaa aaaaggttgg taaaataagc ttatcaaaag
    11521 cgcaaacgtt tgcgttgaat gtgcttgttt ttaaaaagga attgagagtt catcagcttt
    11581 tagctggtta ttcttgattc ctagtccaaa aaaggagagg tcgaatgaaa acatcattca
    11641 aacaattttt tagcttcgag ttttggcaaa aattcgggaa atgcttgatg gttgtcattg
    11701 ctgttatgcc tgctgcaggt ttaatggtga gtattggaaa ttctctgccc atgcttaatc
    11761 aggagtcgca gcttttagcg acgcttggta atgtcattgc tcaggttggt tgggcagtta
    11821 ttggtaacct tcatttgctt tttgcccttg ctattggtgg cagctgggct aaggagcgtg
    11881 ctggcggtgc ctttgcttca gggcttgctt ttgttttgat taaccgtatt acaggggcta
    11941 tctatggcgt ttcttcagcc atgctgactg atccagaggc caagattaaa agtcttttgg
    12001 gcactgagat gattgtcaag gactacttta caagcgtctt agagtcacct gctctaaata
    12061 ccggtgtctt tgttgggatt atcgctggct ttgtgggtgc aacagcctat aacaaatact
    12121 acaattaccg taagctgcct gatgtgctgg ctttctttaa tgggaaacgc tttgttcctt
    12181 ttgtagttat ccttcgttca gctcttgtgg ccctagtatt agccttgatt tggccagtta
    12241 ttcagtctgg tattaatggc tttggcatgt ggattgcctc atctcaggac acagctccaa
    12301 tccttgcgcc attcttatat ggaacattgg agcgtctctt gctgccattt ggccttcacc
    12361 acatgctaac gattccgatg aactatacag ctcttggggg cacctatgag gtcatgacag
    12421 gagcagctgc tggaactaag gtatttggtc aagaccctct ttggctagcc tgggttactg
    12481 accttgttaa tctcaagggc tctaatgcgt caacctatca gcatttgatg gagactgttg
    12541 ttccggctcg ttttaaggtt gggcaaatga ttggtgcaac aggaacgctt atgggggttg
    12601 ccctagcaat gtaccgtaat gttgatgcgg acaaaaagca taaatacaaa atgatgttta
    12661 tctcagcagc ggcagcggta tttttgacag gggtcactga gccactggaa tacatgttta
    12721 tgtttgctgc gatgccatta tatcttgtct atgcccttgt tcaaggagct tcctttgcaa
    12781 tggctgattt ggtcaacctt cgtgtgcatt cctttggtaa tatcgagcta ttgacccgaa
    12841 cgcctatggc gattaaggct gggcttggta tggatttgat taattttgtc tgggtgtcta
    12901 ttctgtttgc tgtgatcatg tatgtcattg ctgactttat gattaaaaaa atgaagctag
    12961 caacagcagg tcgcctaggg aattacgatg ctgatatact agaaaacgat gatacaaagc
    13021 ctttgtcaca gcagtctatt gatggtcagt cacaggtcgt ccaaatcatt aatctcctgg
    13081 gtggacgtga gaatattgct gatgtagatg cttgtatgac tcgcttgcgt gtaacagtca
    13141 atgacccaag caaggttggc agtgaggagc attggaagca ggcgggtgct atggggctaa
    13201 tcatcaaggg cagtggtatt caggctgtct atgggccaaa ggctgatatt ttaaaatcag
    13261 atatccaaga cctgctagac tctggtgcag tcattccaga gccgaagcct gctcagcctg
    13321 ctgcctcatc atcacagcag acggacttta aaaacctaac agaggctgtt ttggcagtag
    13381 cagatggaga agtcttgcca atcacagcag tttctgatca ggtctttgca gctaaaatga
    13441 tgggagatgg ctttgctgtt gagccggcaa atggcgctat ctatgcgccg gtaacaggtc
    13501 tggtaaccca tgtctttcca accaaacatg cctttggctt gctgacagat agcggcctag
    13561 aggtgctggt tcacgttggt cttgataccg ttgacttgaa tggtgagccc ttcactgtca
    13621 aggttagtga gggtcagcgc gtatcggcag gagatctctt ggctgaggct gacctaactg
    13681 cgattacagc agcaggacgc aagacaacgg ttgttgtcgc ctttaccaat actacaagca
    13741 tcaaagctgt taaccttgtt gcgactggtc aacaaaaagc gaagaccctc gttgcacagg
    13801 tagagcttta agaataacca aagagagtgg tagatagcag tatgtcagac ctgcaggctg
    13861 ccacttctct tgtcgtatag gagaagatat gaccaagctc ttaaccctta acacacattc
    13921 ttggatggaa gccaatgcct taaaaaagct gttcgacttg gcagagcata ttttggctca
    13981 gaactatgac gtgatttgcc tacaagaaat caatcagctg attgacagcg aagcagcagt
    14041 gtcattatca ggctaccagc caattgcagg gacacctgcc attcatcagg ataactttgc
    14101 cctcttgctt gtcaattact taaaaaaacg tggccaaagc tactactggt cgtgggccta
    14161 caatcatatt ggctatgata tttaccatga gggtgttgcg atcttatcca agcagccgat
    14221 ccaagcctca gacattttag tctcagcggt ggctgacgag tatgattacc acaccagacg
    14281 ggctttactg gccaaaacaa ccattgatgg cagggaggca gcagttgtga gcctgcattt
    14341 gtcttggttt gatcagggct ttgtcggaga atggcagcga ttagaggcag ccctgcagca
    14401 gctagcctgt cctgtgctat tgctgggaga ttttaacaat ccaagtggcc aagagggcta
    14461 tgagatgatt ctaaaaagcc ccttagacct tcaggatagt catcaggctg cagactacgt
    14521 ctttggagac catagtattg ttgctgctat tgatggctgg gaggataaca aagaggcctt
    14581 taaggtcgac catgtcttta ccagtaaggt ctttaccatt aacagctcaa aggtgacctt
    14641 tgatggtggt gaagcaccgg ttgtcagcga ccattatggc ctagaggttg acctcagctg
    14701 gaagctgtaa caaaaaaagc cagcaggact tgatagactg ctgacactgt aagaaacaga
    14761 tggttatctt agctcttaga agtaagctta tcgcaaggct tctaagagct tttttgcatt
    14821 tatatttcat gagcatatga gaaagttgca gacaaatgct ggacacataa tcagactgtg
    14881 ggctagttac atcgtctgct ctgatttgtg tcagatagtg atgatctgtg ctgccttgtg
    14941 attggccaga tatttacctc atatcaatag cagaaagtca agtctccctc agcctatctc
    15001 ctagcttacg attgctgatc atcagtcagt ctagctacaa ttacctgtgc caagcgctca
    15061 atatcagcac tggtcccgcg tagttcgaaa tctcccagca ttggaaagcc aaagcgctta
    15121 gcatactgct tggctgttag acaatactgg tgattgaagt ttttgttgcc agagccgata
    15181 atccctaaac aacgcttggc attatcatgc gccgcgataa agtctcccag cggattggtc
    15241 aagatttcaa cctcccctga gtcaatcccg tttcctcctt caagataggt cggcaaaata
    15301 gcaacaaagc tctccttgac tgaaaaggtt tcgtgatgaa gctccttgat attgattgct
    15361 ttagtctgta tgtggtgctt ttctgccagg tattgcgaca agcgcctaac aaagctcagg
    15421 gtattgccgc taagactgat aaaaacaagg gtcaagtctg tcataaaaga ctcctttagc
    15481 aagattagtt tcctaaccag cttagcacaa tacccctgaa tacacaactc atatgacaat
    15541 gctctgcacg acaaacgcgc gaaacagtca tttccgaatg atagtataga cttaagcaga
    15601 tacattcacc gttttttcta tagtaaaagc tatagaaaat aagatatctt cttgaaatag
    15661 ctaaacattg acatacagaa agctttgttt tcttgctaaa accctatcat gcgtctgccg
    15721 tgcaatgctc tgacagctag cccactagtc acatcacata aaaaaggctt ggtgacaagg
    15781 acggtaagtc caaatcatca agtcttttta tggagagagc ttagtgttag ctgttacccg
    15841 aatcaagagg cccttgctgc taatgcttgc gattttgata ggtctttggg ctttctccgg
    15901 tatgcttttt gaaaaattta gaaaaatgtg agggatcagt gaagcccaac acgtctgaaa
    15961 tgtgattaat ggcataagca gagcgcagca atgtcttagc ctcttcaatt ttcatgtttg
    16021 aggtgtattg gtagatggtc aagcctgtat cacgcttaaa gatctgtctc agcttggact
    16081 cgctcatgtt aaaatgctgt gccagctcag cggttgtgac actcttatgc aggttgacac
    16141 tgatatattg gataatggca ttaaccgtag gagagacatg tttccagcgg ttgtcccgca
    16201 gctcactcac cttttgggtg taaaagacca gtgaggcatc acgaattttg agcacatctg
    16261 gcattgaggt tgccagctcg ctgtctctca tgaactcctc tcgtgaatgg taggcatcag
    16321 caatatccat accagattga atggcaatct gggctagtcg atcaaaggca atgatagaat
    16381 aatttttttc agagcgcagc gtatcaccac tcaccacagg gataaaggta tttcgtagac
    16441 tgaagatgat ttccttgagc ttgtgcacat caccctcttg aacaatgcta gataaatttt
    16501 tctcataatt gtagagacaa accttagatt cctgcttctt gacaaacata ttggcctttt
    16561 gcacctcgat attgtcggaa aaatccctaa tatagtgacg taaaggaggt gataacaaat
    16621 cctctatctt gccggaaaag aagtaatgga ccacaatcaa gaggtcacga atagcattca
    16681 aaggataaac aggtaaatgc tttagcgctt ggtaaagaat ctcttcttct tccttagtca
    16741 aatccttatc agcaacggcc accttaaaaa aggtcttatc caaaacatta cagcgccaag
    16801 ggccaattaa aatataatga tcctgataac ggtatattaa aaaaagctca ttatagcttc
    16861 cctgaaagaa aagattggtt gcctgttcct tgtccatttg cctaagcact gcttgaaaac
    16921 gataataaaa ttcaaaggta tcatcattcc aaaagctttc tgtcacctga tggtccttat
    16981 caaatactgt aattgataac ttcaaacagc cctgtagaga ttttactaac gacatagtat
    17041 ccatgctaag cgtcaccccc ttcataatcc tcacggtatc ttattctatc ttaaaattta
    17101 agaaaagcaa ggatatgcac ttataatgaa aaaatagaca taaaaaacaa taatatacat
    17161 tcttgcttat taaataaaaa tgacaatgta ctgcataaag aagttcctgt cattaaaata
    17221 aaagtgccat gaggttataa tagtatggta aaacaaaaaa gtgtgcccat aacgggtaga
    17281 gaggaattga catatgtttt tgagaaataa caagcaaaaa tttagcatca gaaaactaag
    17341 tgccggtgca gcatcagtat tagttgcaac aagtgtgttg ggagggacaa ctgtaaaagc
    17401 gaactctgag gttagtcgta cggcgactcc aagattatcg cgtgatttaa aaaatagatt
    17461 aagcgatata gccataagtg gagatgcctc atcagcccaa aaagttcgaa atcttctaaa
    17521 aggcgcctct gttggggatt tacaggcatt attgagaggt cttgattcag caagggctgc
    17581 gtatggtaga gatgattatt acaatttatt gatgcacctt tcatcgatgt taaatgataa
    17641 acctgatggg gatagaagac aattaagttt ggcttcatta cttgtagatg aaattgaaaa
    17701 gcggattgct gatggagata ggtatgcaaa acttcttgag gctaaacttg cagctattaa
    17761 atctcaacaa gaaatgctta gagaaagaga ttcccaactt cgaaatctag agaaggaaaa
    17821 agaacaagaa ctacaaaaag ctaaagatga gcgtcaagct cttaccgaat cattcaacaa
    17881 aactttatca agatcaacaa aagagtataa taaactaaaa acagaacttg caaaagaaaa
    17941 agaaaaagca gctaagatga ctaaggaatt agcagataag ctaagcaatg ctgaagcaag
    18001 tcgtgataaa gcctttgcag tatcaaaaga tttagcagat aaactaagta gtgctgaagc
    18061 aagtcgtgat aaagcttttg cagtatcaaa agatttagca gataaattgg cagctaaaac
    18121 agcagaagct gaaaagttaa tggaaaacgt tggtagtcta gaccgcttgg tagagtctgc
    18181 aaaacgtgaa atggctcaaa aattagcaga aattgatcaa ttaactgctg ataaggctaa
    18241 ggctgatgca gagcttgcag ctgcaaatga caccattgca tcacttcaaa cagagctaga
    18301 aaaagctaag acagagcttg ctgtttcaga gcgtttgatt gaatcaggca aacgtgaaat
    18361 tgctgagcta caaaaacaaa aagatgcttc tgataaggct ttagtagaat cacaagctaa
    18421 tgtagcagag cttgaaaaac aaaaagcagc atcagatgct aaggtagcag agcttgaaaa
    18481 agaagttgaa gctgctaaag ctgaggttgc agatcttaaa gcacaattag ctaagaaaga
    18541 agaagagctt gaagccgtta agaaggaaaa agaagcgctt gaagctaaga ttgaagagct
    18601 caaaaaagct catgctgagg aactttcaaa acttaaagaa atgcttgaga agaaagacca
    18661 tgcaaatgca gatcttcaag cagaaatcaa tcgcttgaag caagagctag ctgacaggat
    18721 taagtcattg tcacaaggtg gtcgtgcttc acaaacaaac ccaggcacta caactgctaa
    18781 agcaggtcaa ttgccatcta ctggtgagtc tgctaaccca ttcttcacta ttgcagctct
    18841 tactgtcatc gctggtgctg gtatggctgt ggtgtctcct aaacgcaaag aaaactaagc
    18901 tatttcctct ttccccaatg gacaatagcc gaaataatag agcgactatc gttctaacac
    18961 aaaagcaaca gtctcctgtc tgttgctttt tgtgatatta gggctcatca gtctaggcta
    19021 atggttttct gcgctttatc tgcagctttg aggattcctt cttttgcttt tacagtgaaa
    19081 gtgttaaaat aggaaaaaca actagtaatt gaggaagtaa atggttaaag aaatcaattt
    19141 atcaggagag gaagtagttg cccttgctgc caagtacatg acagacggtg acgtcgagct
    19201 tgtgcaaaag gcgcttgatt atgcgacagc tgctcatttt taccaggtta gaaagtcggg
    19261 ggagccttat attgtgcacc ctattcaggt agcagcaatc ctagcagacc tgcatttgga
    19321 cgctgtgaca gttgtctgtg gctttttgca tgatgtggta gaggatactg atattactct
    19381 agaggacatt gagtttgact ttggtaagga cgttcgtgac attgttgatg gggtcacaaa
    19441 gcttggtaag gtagaataca agtctcacga ggagcagctg gctgaaaacc accgcaaaat
    19501 gctcatggcc atgtcaaagg acattcgtgt gattttggtc aagctagccg accgactgca
    19561 caatatgcgc accctcaagc acctccgtaa ggacaagcag gagcggattt ctcgtgaaac
    19621 catggaaatc tatgccccgc tagcccatcg cttggggatc agtcggatca agtgggagct
    19681 ggaggatcta gcttttcgct acctcaatga gatcgaattc tacaaaatct ctcatatgat
    19741 gagagaaaag cggcgggagc gcgaagcttt ggttgatgat attgtcacta agattaaagc
    19801 ctacaccacc gatcaagggc tttatggtga tgtctatggc cgtcctaagc acatctactc
    19861 ggtttaccgg aaaatgcgtg acaagaaaaa gcgctttgat cagatatttg acttgattgc
    19921 gatccgttgt gtcatggaga cacaaagtga tgtttacgcg atggtcggct atattcatga
    19981 gctctggcgt cccatgcctg gccgcttcaa ggactacatt gcagcgccta agaccaatgg
    20041 ctatcagtcg attcacacga ctgtttacgg gccaaaagga ccgattgaaa ttcagattcg
    20101 gaccaaggaa atgcatcagg tcgctgagta tggggtagca gcccactggg cctacaaaaa
    20161 aggtattcgt ggcaaggtca atcaagtcga gcaaaaggtt ggtatgaatt ggattaagga
    20221 gcttgtcgag cttcaggctg cctcaaatgg cgatgctaag ggctttgttg actcggtgaa
    20281 ggaggacatc ttttcagagc gtatctatgt gttcacaccg acaggagcag tgcaggaatt
    20341 gcccaaggat tcaggcccta tagactttgc ctatgccgtt cacactcagg ttggtgaaaa
    20401 ggcgacagga gccaaggtca atggccgcat ggtgcccttg acagccaagt taaaaaccgg
    20461 tgatgtggtg gaaattgtca ccaatccgaa ttcctttggt cctagtcgtg actggattaa
    20521 gctcgtcaag accaataagg ctcgtaacaa gattcgccaa ttctttaaaa atcaggacaa
    20581 ggagctgtct atcaataaag gacgtgagct tctggttagt tattttcaag agcagggcta
    20641 tgttgccaac aagtaccttg agcgtaagcg tattgaggag attttaccaa aggtcagtgt
    20701 taaaagcgag gagtctctct atgccgctgt tggctttggc gatattagcc cagtcagtgt
    20761 ctttaataaa ttaaccgaaa gagaaaggcg tgaggaggag cgtgccaagg ctaaggctga
    20821 agctgaggag ctggttaagg gcggtgaggt caagcatgaa aacaaagaga ttctcaaggt
    20881 ccgcagtgaa aatggcgtga ttatccaagg ggcgtctggg cttctcatgc gtatcgccaa
    20941 atgctgcaat cccgtaccag gagatgtgat tgaaggctat attaccaagg gacgaggcat
    21001 tgctattcac cgcgcagact gtaataacat caagagtcag gacggctatc aggagcgtct
    21061 cattgaggtt gagtgggatt tggagcattc tagcaaggat taccaagctg agattgatat
    21121 ttatggttta aatcgtatcg gcctgctcaa tgatgtcctg caaatcctat ctaacgccac
    21181 caagagcatt tcaactgtca atgcccagcc gaccaaggac atgaagtttg ccaatattca
    21241 tgtgagcttt ggcattccta atctggctca gctgacagct gttgttgaaa aggtcaaggc
    21301 ggttccagat gtttacagcg tcaaacgaac caacggataa aaaggagacc aaccatgaaa
    21361 attgtgattc agcgcgtcaa ggaagcctca gtgtcgattg atgggaaaat agctggcgct
    21421 attgatcaag ggctgctgct gcttgttggc ataggtccag atgatcaggc agaggatata
    21481 gactatgcag tgcgtaaaat cagtcatatg cggatttttt cagaccccga gggcaagatg
    21541 aaccgatcca ttcaggacat tgagggcagt gtcttgtcta tctcgcagtt tacgctatat
    21601 gctgacacca aaaagggcaa ccgacctgcc ttcaccgggg ctgctaagcc tgacagggcc
    21661 agccagcttt ataacagctt caacgctcag ctagagcagc ttgtaccggt tcagcgaggg
    21721 gtctttggtg cggacatgca ggttagtctg atcaatgatg gcccagttac gattatccta
    21781 gatacgaagt atcgataact gcctagcgat cgatcgtttg cttaggagag tcatataaag
    21841 gaaaaacaaa aagacgagtg gtatgagaag cactcgtctt tgtcgtttat gctgctgtgt
    21901 tgaagctagc tagggctact agtcttattt ttgcaggtct ttgtagactg cgatgaattc
    21961 tgtctcagaa attggggtta agctgccagt gaattggtaa gaagtaccat ttttagcttg
    22021 gaaagtatta ggtaaacctt taaggtattt gtcgatagtc tcagtggtaa ttgcttcgtg
    22081 tgttttaaag gtgtattcgt taatcagctg ctgctgtttg tcctgttggt aaatagtaac
    22141 tgaacgatag gttgtgctat agtcatcgtt aatatcctta gaaataaaat aggtttctac
    22201 aacagaatct gaatgtgtcg catagctaat gggattgttg acgtcatact ttgaattata
    22261 tacttgagct atcctgttag aatctatgat atagttaaag tcctcatcgc gatcagcatg
    22321 gtagaccatg cgttcactag ctccactgta aatctcaccg ttatggcttt gatgagttat
    22381 atcaggatcc tgcgtgactg ttgtactgat tcgcttgacg agctgatacc cgtctttgaa
    22441 agcctgagtg gtttcaaaag cctttttagc agcttcaaag agctcctcag aagagaccct
    22501 gctgccatag tatcttaacc cggtaagtcc ttctttacca aggctgtcag ttacatcaac
    22561 attaacaagc tgcccattgt cttttttgag gaatttaacg tgctgtgtca cagctacggc
    22621 atctgaatct tggattgggt ttcctgcctt atctgttacc ttaatgtcct tgagagctac
    22681 cttgctaact ttttccacaa ggacctgacc cgtcaagatg tatgtttggt ctttttgatg
    22741 atactgtcct ttgattggtg tcgtaaaatg gtctgtgcta agtatttcag ctgtagaagc
    22801 ttttgttaat ttggcatttt tcaaactaat gaccttaaag ctttctgctg aaggatctat
    22861 gacgtcttga actagcttta tcatctcatt tgtggtgtag gttttgccat attctagtct
    22921 aatatcctga taatgtggag atacgatggt gtgattagtg ttatctactc cagtgatatt
    22981 gaccatgagg tacagtcctg tggtttcttg atagtctttt gaatggattg gcttagtggt
    23041 gtcctcgtat ttatagtgat ttgctaccct actagagctt gaccatgccc acccaacttt
    23101 gtaatggttt gctttaacgg caggtgctcc caaggtcatg gtgaatagtc caatgactac
    23161 agttcctatt tctaaaggtg ttttcccaag gtgatacagt ctttttgaag tcaacatatt
    23221 tcaaacctcc ctaaatcctg tcagtctcta tagttataaa aatacagaga atcgttagaa
    23281 gaattaatgt ttcatgccgg caagatgagt gtaacaaaag attggtgccg atacaagaag
    23341 atggagatta gagcatctgg tttcaatgag agttacataa tagcagaagg ttttttcact
    23401 atgagagcta atcgtcttaa aatggtataa tagcaagtga ataggctatc taactggttt
    23461 aacagccatt tttagagaag cttaatagta ttgctgataa gtgactcgta tctccatatt
    23521 gcttttcaaa ggctatgtta gctatgataa gcgtgaccag gctatcggaa aatccagtgt
    23581 tcttaaaggc tttgaagctc tggctttgaa ccttagctct ggtgtttcta tgaaaatgac
    23641 ttgggccttg taccagataa gaatgaagtc aaattgaggt tttttgacaa aatgtttgag
    23701 taaatacaag ttcatagaag tctaatgtat aaaaatacaa ttgtatcgcc ataatctgaa
    23761 tgaccaaacc attaaaaaaa taaaattttt aaacattttg gaaaacgctt tcaaaactaa
    23821 aaagaactgt cctatagtca ttgcttagca ttaaagcaag gtgtgaaatg ttatcatatg
    23881 gagaaatagg ctgtcttgtg ctgtatctgt gccaaaaaag aatgcttgtt tttgtgatat
    23941 aatgtgacta agaaacctga aaggaatgct tatggcatta aaagactatt ttcctgatat
    24001 gcaagagggt gcatttcctc tggctgacca agattggatt agcgttgagg ttggggagca
    24061 gtacctccat ttccccaaat ccagcttgtc agagcgagag cagcttttgc ttggtttggg
    24121 gcggcagcgc aaagagccgt ccaaggatca gaaatctcct tggtatcatt atttgattct
    24181 gggccaaggg gagcagccgg aggagtttca gggttgccag ttcatctata tcaaccatca
    24241 atgtccttta gcaggtgatt tgattgagct tctaaagggg atcatagagg gagttgaggc
    24301 tgttttgccc attagccaga ccaggacagc ttttttggtc tgtcaccata gccgttcaga
    24361 cctttttcag ctcttagcaa atttattgcc cacgattgag agcgattttg gtttggcctt
    24421 gatgattttt atcggtaatg gctggtatca ggtgtcagga aatgccttga gagactattt
    24481 taaggaagaa aatgctgtgt ttacagctta tcttgctgag cactctgcca gtcgcttgct
    24541 gaccttttca gaggtcatgc tctggtcact cttagcaaac agtggtttgc cagccttgtc
    24601 aaagcatttt agtcagctgc ttttagccaa taaagaggtc atggatctgg tgctcgccat
    24661 gtggcaggag catggcaacc tggtacagac agcccagcgc ttgtatattc atcgcaattc
    24721 gctgcaatat aagctggata agtttgctca gcagtcaggt ctctatttaa agcagctaga
    24781 tgacttggcc tttgcttatc tatttatact gaagcattag atttgtgcag ggtgcccaaa
    24841 gacatttggg cgttttgtct atatgatgaa aacgctatct ttgctataat aaaagcatca
    24901 aataaaaagt gtcagggttg ctagcattgc agtcagctag cagcctatct gacccattag
    24961 gagtaacgca tggttgaatt aaacttaaag cacatctata agaaataccc aaataccaca
    25021 cactatgctg ttgaggattt cgatttagac attaaggata aggaatttat cgtttttgta
    25081 gggccttcag gctgtggtaa gtcaacaacg cttcgtatga ttgctgggct tgaggatatt
    25141 tcagagggtg aattgaaaat tgacggtgag gttgtgaatg acaaatcacc aaaggaccgc
    25201 gatatcgcga tggttttcca aaactatgcc ctttacccgc atatgaccgt ttatgacaac
    25261 atggcctttg gtctcaagct acgtaaatac aaaaaagatg atattgatcg tcgtgtcaag
    25321 gaagcagcag aaatccttgg cttgacagaa tttttagaac gtaagccagc agacctttct
    25381 ggtggtcagc gtcagcgtgt ggctatggga cgtgctatcg tgcgtgatgc caaggtattc
    25441 ttgatggacg agcctttgtc aaacctagac gctaagctgc gggtgtcaat gcgtgctgaa
    25501 attgcgaaaa ttcaccgccg tatcggctca acaacaatct acgtaacgca cgaccagacc
    25561 gaagcgatga ccttggcaga tcgtatcgtt atcatgagtg ccactaaaaa ccctcaaggc
    25621 aacggtacaa tcggaaagat tgagcaggtt ggctcaccac aggagctcta taacctaccg
    25681 gccaataaat ttgttgcagg ctttattgga agccctgcga tgaacttctt tgaggtggtt
    25741 gtcaaggacg gtcagatcat cagtgaggac gggcttgata ttgctattcc agaaggtcag
    25801 gctaaaatgc ttgaagcagc tggctataag ggcaagaagg ttatttttgg tatccgtcca
    25861 gaagatattt caagcaacca aatcgtgcat gacacctatc caaatgccaa tgtcacagca
    25921 gaggtcttgg tttctgagct gcttggatct gaaaccatgc tttatgttaa gcttggtcaa
    25981 acagagtttg cttcacgagt tgatgcgcgt gacttccaca atccaggtga aaaggttagc
    26041 ttgaccttca atgttgctaa ggggcatttc tttgatctag aaacagagca agctattcgc
    26101 taataacacc tcctagaata aaatcctcat cttgcttgag gattttttaa caaaagaaaa
    26161 tgcaagcgat tgcgctatca aaaagaaaaa gggatttatc ataaagacaa cagatgttct
    26221 gtagtgctag gcgatcataa tgatggcacg aaatagcagg agactgttta gtaataagga
    26281 gatatgatgg aaaaacactg gtggcataaa gcgacaattt atcaaattta cccaaggtcc
    26341 ttcatggata caagtgggaa tggtattggt gatttaaaag gaatcacagg taagctggat
    26401 tatctacagg agctagggat cacagctatt tggctgtctc cagtttatca atcaccaatg
    26461 gacgataacg gctatgatat ttcagactat caggccattg cagctatttt tggtgatatg
    26521 gctgatatgg acgagctgct tgatgaggcc aagcagcggg ggatcaaaat catcatggat
    26581 ttggttgtca atcacacctc tgatgagcac gcttggtttg tggaggcaag agaaaatcct
    26641 gacagtccta aacgagatta ttacatttgg cgtgatcagc ctaataatct catgtcgatc
    26701 ttttctggct ctgcttggga atatgatgat gcctctgggc agtattatct gcacatattc
    26761 agtaaaaaac agcccgactt gaattgggaa aatgctgaat tgcgtcaaag catttatgac
    26821 atgatgaatt tctggattga taaggggata ggtggctttc gcatggacgt cattgacctg
    26881 attggtaaga ttccggattc tgaaattaca ggcaatggcc caaggctgca tgaatacctc
    26941 aaggagatga accaggcaag ctttgggaat catgacctga tgactgttgg tgaaacatgg
    27001 ggcgctacac cggaaattgc tcgtcagtat tcacgtcctg aaaataagga gctgtcaatg
    27061 gtctttcaat ttgaacatat cggcttgcag cataagccaa atgcttctaa atgggattac
    27121 gcagctgagt tgaatgttcc ggctctcaag gagattttta gcaagtggca gacagagcta
    27181 aagctaggtg aaggctggaa ctcccttttt tggaacaatc atgacttgcc tcgtgtcgtc
    27241 tccatttggg gaaatgatac agtatataga gagaagtctg ccaaggcaat ggctattttg
    27301 ctgcatttaa tgcgtgggac accttatatt tatcagggtg aagagattgg catgaccaat
    27361 tacccctttg agcgcttgag tgatgtgaat gatattgaat cactgaatta tgccaaggag
    27421 gctatggcta atggcatgtc agaggaggct gttcttgatt gtatttgtag ggtgggtcga
    27481 gacaatgcaa gaacaccaat gcaatggagc agtcaaaaga acgccggctt ttcaactgct
    27541 gatcagacct ggctgcctgt caacccaaat catcaagaga ttaatgtggc tagtgctcta
    27601 gctgatcctg attctgtttt ttacacctat caaaagctta ttcagctgcg tcagacacag
    27661 gattggctgg tggaggcaga ttatcagctg ctggaaacat cagataaggt ttttgcctat
    27721 aagcgtcagc ttggtagaga gacttacctt gttgttgtca atctgtctaa tcaagagcag
    27781 ttttttgaag aaagtcttca taaggcccaa gtgattatca gcaataccga tgtgcaggca
    27841 gtcgtagaaa gtcaacagct ggagccttgg gacgcctttt gtgttaagct tgatgagacc
    27901 ttgtagccta gctgcttgct gtgcctcagc tcaataatcg tagcgattct ttgagaattt
    27961 tgacaaattg ctgtatgatt agtagaagaa ttagatacaa aagaggaggc tgagatgacc
    28021 gttgaagaaa ccatgacctt tgcaaaaagc attgcagcat ttagataggt agagattagt
    28081 gaggtagtca ctaggctagc agcaggtgag gacatcaccg tctttttagg cagagcgacc
    28141 tgtccttatt gtcgtcgctt tgcacccaag ctagcaagcg tagcaaggca ggagcataag
    28201 gatattttct ttgtagatag tgaagactca acagagcttg cagacctgca ggcctttcgt
    28261 gagcgctatg ggcttgctac tgtgcctgcc ctgctcatta gtcgtcatca ggaggtcaag
    28321 gcagtctgtg attctagctt gactgaggaa gccattttgg ctttcctaga gcagtgacag
    28381 acagctaatt atctggtgca agtaatagaa atgtaatcag tcatgtcttg ctatgtgagt
    28441 ccaaatctgc tatagtagga catgactttt agacgaaata aggagatatt atgggcttac
    28501 caacaatttt aatgtttgtt gtcatgattg gtttaatttg gtttatgcag cgtcagcaaa
    28561 aaaagcaggc gcaggagcgc caaaatcagc ttaatgcgat tgaaaaaggc gatgagattg
    28621 tgacgattgg tggcatgttt gcagtggtcg atgaggttga tttagcagca aagcgaattg
    28681 tcttagatgt tgatggtgtc tatctgccat ttgagctatc agcgatcaag cgcgtggtcg
    28741 aaaaaggaag tgcagtgaca tcagctgatg tggatacgac agagactgca gttgatgaca
    28801 cagcggttga ggcttcagac gaagctgaat cagctattga gacaaattaa gaaaatgagg
    28861 tctgaagcat tagtgtttca gactttttta ggtgatgata gcaggtagcc agacagagct
    28921 gtcatgtgct atggaaatat cgtctacaac gagaaaaagc gagccaaacc gcatgaaata
    28981 tggtaaaata tgaggtaagt atgcttgtga ataaggaaaa aacatgtttg gattaaaagc
    29041 gaagtcaaaa aaaatcgttt tggataggat tccaaagcac attgggatca tcatggatgg
    29101 taatggacgc tgggcgaaaa aacgcttaaa gccgcgtgtc tttggacata aggcgggtat
    29161 ggacgctttg caggaggtaa cgattgcagc ttcagattta ggggttaagg tgttaacagt
    29221 ctatgccttt tcgacagaaa attggtcaag accacaagat gaggtgagct tcattatgaa
    29281 cctgcctgtt gagttttttg ataagtatgt gcctgagctg cacaaaaata atgtcaaggt
    29341 gcagatgatc ggtgagacca accgcctacc taaggataca ctaaaggcct tggaagcagc
    29401 tattgctaag acaaggcaaa atactggctt gattctaaac tttgctctta attatggggg
    29461 tcgcgcggaa atcaccaatg ctgtcggtct cattgctcaa gatgtcctag acgccaagct
    29521 gaaccctggt gacattaccg aggatttgat tgccaactat ttgatgacgg atcatttgcc
    29581 ctatctctat cgcgatcctg accttattat cagaacgagc ggtgaattgc gcttgagtaa
    29641 ttttatgcct tggcaatcag cctatagtga gctttacttt acgccggtgc tgtggcctga
    29701 ttttaaaaga gctgaactac taaaggccat agaggattat aaccatcgtc atcgccgttt
    29761 cggtgctatt taaggagaga gtatgagaga acgtttcatt tggggtggtg ttgcagctgc
    29821 tgttttccta ccctttttac tcattggcag cttacccttt caattgtttg taggtgtgct
    29881 tgccatgatt ggtgtatcag agctgttaag aatgaagagg cttgaggtct tttcctttga
    29941 gggtgttttt gccatgctag cagctttcgt tttgacagtg ccgttggatc attacctgac
    30001 ctttttgccg atggacgcta gttttgcttg ttacgggctg ttggtgtttt tccttttagc
    30061 aggaatagtg attagcagcg attcttatgg ctttgaggat gctagctttc cgattgcagc
    30121 tagcttatat gttggtattg gctttcataa tctggttaat gcgcgaatga cagggataga
    30181 caaggttttt ctggctcttt ttattgtctg ggcgactgat attggagctt acttgattgg
    30241 gcgccgattt ggtaagcgaa agctcctgcc aaaaatatca cccaacaaaa caattgaggg
    30301 cagccttggt ggtatagtca gtgcggtgct tgtttccttt gtgtttatgc tctttgataa
    30361 ggctgtttat gctcctcatc attttggaac aatgttgatt ttggtggctc ttttttctat
    30421 ttttgctcag tttggagatt tggttgaaag tgctgtcaaa agacatttcg gagttaagga
    30481 ctcaggcaaa ttgattccag gccatggtgg tattttagat cgttttgatt cgatgatctt
    30541 tgtttttccc attatgcatc tatttgggtt attttaaagc tcattatcaa tagactgaaa
    30601 ggaaatctat gttaggaata attaccttta ttattatttt tggtattctt gtgcttgtcc
    30661 atgagtttgg ccatttctat tttgctaaac gatctggtat tttagtcaga gagtttgcta
    30721 ttggcatggg accaaaactc ttttcgcatg ttgatcagca aggaacgctt tacacgatcc
    30781 ggctattacc gcttggtggc tatgtgcgaa tggcaggctg gggtgatgac acaactgaga
    30841 taaaaacagg aacgcctgct agcttaacgc ttaatgatca gggcttggtc aagcggatta
    30901 acctgtctca gagcaagctt gatccgacta gcctgcctat gaatgtgact gcttatgact
    30961 tagaagataa gttgacgatt acagggctgg ttcttgatga gatcaagacc tattcggtag
    31021 accatgacgc gaccattgtc gaggaggacg gtacagagat ccggattgcg ccgcttgatg
    31081 ttcagtatca aaacgcaagc attggcggtc gtttgatcac caattttgca ggacctatga
    31141 ataattttat tctaggtatt gttgtcttta ttttgtttgc ctttgttcaa ggtggtgtgg
    31201 ctgattatca tagcaaccat attcgtgtgg tggaaaatgg cgcagcagcc aaggctggta
    31261 ttagagacaa tgatcagatt ttagagatta atcatcaaaa gattaatgac tggtatgagt
    31321 tgacgcaggc cgttactgat tcagcagcag atgttaaggc taagggcaag ctagagatta
    31381 cctatcagac aggtgatcag gttaagacta tagcactgaa gcctgaaaaa aaaggcgatc
    31441 agtaccttat tggtgtccag tacccactaa aaacaagtct gacagacaag ctaataggtg
    31501 gctttgagat ggctggtaat ggtgctctag tgattgtcac tgctctaaag agtttgatta
    31561 cctcctttag cctagataaa ttaggtgggc cagttgccat gtatcagatg tccaatcagg
    31621 cagcaaagaa tggtttagag tctgtcttgt ccttgatggc aatgctctct atcaatttag
    31681 ggatttttaa tttgattccg attcccgcac tagatggtgg taagatcctg atgaatgtga
    31741 ttgaagcact tcgtcgtaag ccattaaagc aagagacaga gacttatatt acccttgcag
    31801 gtgttgcgat tatggtggta ctcatgattg cagtgacctg gaacgatatt atgcgagcct
    31861 ttttccaagg ctgatggtct ctctcattta aaggagagcc taaaaggctt aatgtaacag
    31921 aaataacaag agatatagtg tcattattgt ggttctaaga ccttgcaaat gcagcaaaag
    31981 cttagccaat atagctcatt ttgtctcttt tttagaaatg aattctcaac gaaaggaaag
    32041 agagctgttg accaagctgg gctaaggcct acagctgaaa tcaaaatgct agacctgcta
    32101 ttagtctaag ggcgttttga gctgctctct atagcttatt ttaatgaaac aaagtaaaat
    32161 gcttatccca accctgcgcg aaatgccaag tgacgctcag gtaatcagtc atgccctcat
    32221 ggtgcgtgcg ggctatgtcc gtcaggtatc tgccggtatt tatgcctatt tgccattagc
    32281 tcatcgtaca attgaaaaat tcaagacgat tatgcggcag gaatttgaca aaattggtgc
    32341 tgttgaaatg ctagcacctg cccttttaac agctgacctc tggcgtgaat caggccgcta
    32401 tgagacttac ggtgaggacc tttacaagct aaaaaaccgc gacaaatcag actttatctt
    32461 aggtcctacc catgaagaaa cctttactac actggtgcgt gatgcggtta aatcctataa
    32521 gcagctgccg ctcaatctgt atcagattca atccaaatat cgtgatgaaa agcgtcctcg
    32581 taatggcctg cttcgcacac gtgaatttat catgaaggac ggctatagct ttcatcaaag
    32641 ctatgatgat ttagatgtca cctatgacgc ctatcgtcag gcctatgagg ctatttttac
    32701 cagagcaggc ttggatttca aaggaattat cggtgatggt ggtgctatgg gtggtaagga
    32761 ttcgcaggaa tttatggcta tcacaccgga ccgtactaat ttagaccgct ggctggtctt
    32821 agacaagtct attccgtcat tggctgacat tccagaggag gtcttggaag agattaaggc
    32881 cgagctggct tcatggctgg tttcaggaga ggacaccatt gcttattcaa gtgaatcaag
    32941 ctatgctgct aaccttgaga tggcaaccag tgagtacaag tcctcatcaa aggtaacagc
    33001 cttagatgat ctcgtcgaga ttgagacacc aaattgtaaa accattgatg aagtggcggc
    33061 ctttcttgac gttgctgagc atcaggtcat taaaaccctg ctctttatgg tggaccatga
    33121 gcctgtgctt gctttattgg ttggaaatga ccagatcaat gctgtcaaat tgaaaaacca
    33181 cctcggtgca gacttcttag agccagctag cgaggaggag gcgcgtgcta tcctaggtgc
    33241 aggctttggt tcacttggtc cagttcattt gacagatggt atccgtattg tggctgatcg
    33301 taaggtccaa gaccttgcta atgctgtagc tggagccaat aaagatggtt atcacctgac
    33361 tggtgtcaat ccaaatcgtg atttccaagc agagtatgct gatattcgtg aggtaaaaga
    33421 gggagagacc tctccagata gacatggcgt gctgcagttt gccagaggta ttgaaatcgg
    33481 tcatatcttt aagctgggga cccgctattc tgatagcatg gcagctaata tccttgatga
    33541 gaatggcaga gcagttccga ttgtcatggg ctgctatggt attggggtta gtcgtatcct
    33601 atcagcagtc attgagcagc atgctcgtct ctttgtcagc aagacaccaa agggtgatta
    33661 tcgctatgct tgggggatta atttccctaa agagctagct ccgtttgatg tgcatttgat
    33721 taccgttaat gtcaaggatc aggaggcgca ggacctgaca gaaagagtag aggctagtct
    33781 gatggccaag ggctatgatg tcctcactga tgaccgcaat gagcgtgtcg gctctaagtt
    33841 ctctgatagt gatttgattg ggcttccgat tcgtgtgacg attggtaaaa aagcagctga
    33901 gggcattgtt gagatcaaaa tcaaagcaac aggtgacagc attgaggtgc acgctgatag
    33961 cttgattgaa actcttgaca ttctcacaaa ggacaactaa tgatatgagg tcaacgatgg
    34021 ttgatctctt tttgtatgct ataatgaaag catgacaatt gaggaattac agcagctggt
    34081 gctagcagat catgagctaa tgactattct aagcattata gagaccttgc ctttaaagga
    34141 ttgttggctg gcagcaggtg caattcggaa cgctatttgg aatcatttag cttatgggat
    34201 aggctttgat ccgctgacag atgtagatgt ggtctttttt gaccctgaga tctcttacga
    34261 agctgagcag ctgctagaag agcagcttaa gtgtgcttat cccatgtacc aatgggaggt
    34321 tcgcaatcaa gcctatatgg cagcacataa ccccaagacg cctccttatc gatctagtca
    34381 agacgctatc acaaagtatc cggagcgctg tacagcgatt gctgttagac ttgtaggagg
    34441 acagctagag gtttttgctc cctatggttt agcagacatt agtcactttg tctgtcggcc
    34501 aacaccgcat tttttagagg attcagagcg tatggactgc tataggcagc gcctagcaaa
    34561 gaaggactgg cacaagaaat ggccacagct gacctaccac gactgctaag tcagaggaaa
    34621 caaagcaggc taggagctcc gtacagccaa gcaattagtc cgctcccaga cccgttagct
    34681 acagctctca cctagtcaaa acaagcacat gaacagatca ttggcagata gccttgcctt
    34741 tgcagatatt gtcacaccct atttagctgt accatgtgtc ttatgatagg cgtgatagtg
    34801 ctgtcagaag cgccagctga gccagaaaaa gcgttaagcc tacagcaagg ggcttttaac
    34861 ctttggtatg ttgtcttgta ggagaggtcg aaaatgatca ctatttatga taaaatagac
    34921 cctaagaaaa tcaggagaaa gctatgtcag atttattcgg taaattgatg gaacaaattg
    34981 aaatgccact tgagataaga caatcaagtg ccttttcgtc tgctgatatt atcgaggtca
    35041 aggtgcattc agtgtctcgt ctgtgggaat ttcatttttc ctttgcagag gttctcccga
    35101 tagagagcta tcgagagctg tcagataggc ttgtgagaac ctttgaggca gcagatatta
    35161 aggtaacatt tgacatcaag gcagagacaa ttaattattc ggatcagctg ctgcaagcct
    35221 actatcaaga agcatttgag catgagccct gtaatggggc tagcttcaag tcatcttttt
    35281 ctagacttca ggtcaggtat gaccatcatc agctgatcat tatggcacct gactttgtga
    35341 ataatgatca ctttaggaaa aatcatttac ccaatctggc agctcagttt gagcgctttg
    35401 gctttgggag gctagcgatt gatatggtgt ctgatcagga gatgacagac catttgacaa
    35461 aggactttga gaccaaccgt caggctctgg tggaaaaggc tgtacaggat aatatcgcag
    35521 cacagcaatc attggaggcc atgcagccac cagctgagga ggcagcacca agcccaagcc
    35581 ttgactatag agagcgtatg gctcagcgcc aagcaagctt tgataaggcg gtcattacac
    35641 caatgattga ggtggataca gaagaaaatc gcattgtttt tgaaggaatg gtctttgatg
    35701 tggagcgcaa gacgacaaga acaggccgcc atatcatcaa cttcaagatg acagattaca
    35761 cctcctcctt tgccatgcaa aaatgggcca aagatgacga tgagctcaga aaatttgatc
    35821 tgattgcgaa gggagcttgg ctgcgcgttc agggaaatat cgaaaacaac cccttcacca
    35881 agagcctaac catgaatgtg cagcaggtta aggcgattgt tcaccatgag cgtaaggatc
    35941 tcatgccaga agggcaaaag cgtgttgaat ttcatgcaca cactaatatg tccacaatgg
    36001 acgctctacc gacggtagaa gacctgattg atacagcagc caggtgggga catcaggcag
    36061 tagcgattac tgaccacgct aatgttcaga gctttccgca tggctatcat agagcacgca
    36121 aggcaggaat caaggcaatc tttggcttag aggccaatat tgttgaggat aaggtaccta
    36181 tttccttcaa tcctgtcgct atggacctgc atgaagccac ctatgttgtc tttgacgtgg
    36241 agaccaccgg cctttctgcc atgaacaatg atttgattca gatcgcagct tccaaaatgt
    36301 tcaagggaaa tatcattgag cagtttgatg agtttatcaa tccaggccac cccttatctg
    36361 cttttacaac agaattgaca gggattacag ataatcattt ggtaggagct aagcctatac
    36421 agcaggtgtt agaggcattt caggcctttt gtcagggcac tatcctagtt gcccacaatg
    36481 ctagctttga cgtgggattt atgaatgcca actacgatcg gtatggttta gcaaaaatca
    36541 gccagccagt tattgacacc ctggagcttg ccagaaacct gtaccctgag tataagcggc
    36601 atggcttggg ccctttgact aagcgctttc aggttagcct tgagcaccat cacatggcca
    36661 attacgatgc tgaagcaaca gggcgtttgc tctttatctt cctaaaggaa gctagagaaa
    36721 agcatgggat tacaaacctg cttcagctca atacagactt agtggcagag gattcctata
    36781 agaaagcacg gatcaagcac gccacgatct atgttcaaaa tcagctaggt ctcaaaaaca
    36841 tgtttaagct ggttagcctt tcaaatgtga aatattttga aggtgtgcct agaattccaa
    36901 gaaccgtcct tgatcagcat cgtgaaggct tgctgcttgg gacagcctgc tcagacggcg
    36961 aggtctttga cgccgttttg acccaaggaa ttgacgctgc tgttgatctg gccaaatact
    37021 acgattttat cgaaatcatg ccgcctgcaa tttaccagcc cttggtagtc cgagagctaa
    37081 tcaaggatca agcaggagtt gagcagatta ttcgcgattt gattgaggtc ggccgcagag
    37141 ctgaaaagcc tgtcctagct actggaaacg tgcactacat tgagccagag gacgccatct
    37201 atcgtgacat tatcgttcgt agtctagggc aaggtgccct gattaaccgt actattggcc
    37261 gcggagaggc tgccaagcct gtcccgctac cagaggctca ttttagaaca accaatgaaa
    37321 tgcttgatga ttttgccttt ttaggtcagg acttggccta tgaggttgtg gtgcaaaata
    37381 cccaagccct tgctgatcga attgaaaagg tggaggttgt taaggatgat ctgtacaccc
    37441 catatattga taaggcagaa gaaaccgttg ctgagctgac ttatcaaaag gcctttgcta
    37501 tctatggcaa cccacttcca gatatcattg atctgcgcat tgaaaaggag ctaacgtcca
    37561 ttttgggaaa cggctttgcg gtgatttatc tagcctcaca aatgctggtt aatcgctcta
    37621 atgagcgtgg ttatctggta ggctcacgtg gctctgttgg ttcaagcttt gttgcgacca
    37681 tgattggcat cacagaggtc aatccaatgc cgcctcatta tgtctgccca agctgccagc
    37741 agtcagagtt tatcacagat ggctcggtcg gctctggcta tgatttgcca aacaaggcct
    37801 gtcctagatg tgggacgctg tacaaaaagg acggacagga tattcctttt gaaaccttcc
    37861 ttggctttga tggtgataag gttccagata ttgatttgaa cttctcagga gatgatcagc
    37921 ccaatgccca cttggacgtt cgtgatatct tcggggaaga atacgccttt cgtgcaggta
    37981 ctgttggtac tgtcgctgaa aaaacagcct atggctttgt caagggctat gagagagatt
    38041 atggcaagtt ttacccagat gcagaggttg atcgtctagc tgctggtgct gctggtgtta
    38101 agcggacgac tggtcagcac cctggtggga tcgttgttat ccctaactat atggacgttt
    38161 atgattttac acctgtgcag tttccggcag atgatgtgac agcctcatgg cagacgaccc
    38221 actttaattt ccatgatatt gatgaaaatg tcctaaagct cgatgtactc ggtcatgatg
    38281 atcccaccat gattcgtaag ctgcaggatt tatcaggtat tgatccgatt actattccag
    38341 cagatgatcc tgacgtgatg gcactttttt ctggaacaga ggtgctcgga gtgactcctg
    38401 aacaaattgg aacaccaaca ggtatgcttg ggatcccaga gtttggaacg aactttgttc
    38461 gtggcatggt gaatgagacc cacccaacga cctttgcaga attgctgcag ctatcaggtc
    38521 tatcgcatgg aacggacgtc tggctgggta atgctcagga tctgatcaaa gaaggcattg
    38581 ccaccctaaa aacagttatc ggttgtcgag atgacatcat ggtttacctt atgcatgctg
    38641 gtctagagcc taagatggcc tttaccatca tggagcgtgt gcgtaagggg ctctggctaa
    38701 agatttccga ggaggagcgc agctcctata tcaaggccat gcggcaaaac aacgtcccag
    38761 actggtacat cgaatcctgt ggtaaaatca agtacatgtt ccccaaggct cacgctgccg
    38821 cctatgtttt gatggcattg cgagtggctt atttcaaggt tcatcacccc atcatgtatt
    38881 actgtgctta tttctctatt cgtgccaagg cctttgagct caaaaccatg agtggtgggc
    38941 tagctgctgt caaggctcgc atggaggaca tcagcaacaa gcgcaagcgc aatgaagcct
    39001 caaacgttga aaatgacctg tttaccactt tagaaattgt caatgaaatg cttgagagag
    39061 ggtttaagtt tggcaagcta gacctttaca agagcgaggc aactgagttt caaattgaag
    39121 gggataccct aattccacct tttattgcct tagaaggctt gggagaaaac gttgctagac
    39181 aaatcgtcaa ggctcgccaa gatggtgaat ttctatcaaa aatggaatta cgcaagcgtg
    39241 gtggtgcttc tgccactcta gttgataaga tggacgagct gggcatttta ggaaatatgc
    39301 cagatgacaa tcagctgagt ctatttgatg actttttcta agattgcaca gccctaatat
    39361 tgtctatgtt agcttgtcat acagtgaaga gcagggcagg aaggcttcct gtcctctttt
    39421 tgtcaatacg caaagaaagc ccaaaaaaga acgaggaaaa gcatgaatga attagacaaa
    39481 aatcctgcct taaaggcaat ggttgttttt agaaaagcac agcgtacctt agatgctcaa
    39541 agctccgcct tttttcaaaa ggccaatctg actcctaccc aatttagcgt cttagaggtg
    39601 ctttattcca aaggaagcat gagaattaac aagctcatcg gttctctctt ggcaacctct
    39661 ggcaatatga ccgtagtgct gaaaaatatg gagagaaatg gctggatcag ccgctgccaa
    39721 gatgctaaag ataagcgtgc ctgcttggta cagctaacgc cagagggcaa agccttgatt
    39781 gagactatcc tacctgagca tatcaaacgt gttgaagccc ttttttcagt gctgacagag
    39841 actgagcaaa aacaattgat tacgctttta aagaaattta aagaactcta agcaaatggc
    39901 tttacaggat ctcccaagta ggatataatc actacatagt acaaaaagat actaactagt
    39961 cataataagt catcaagaca gcagatggct agttaccaga taatcaatgg gagacaaagc
    40021 atgaaacaaa ttttaatcat taatggttca ttacggacag gttcatttaa tcatcagctt
    40081 gctcaagcgg ctgagcagct acttgaaggc aaggcagctg tatcttactt ggactgggaa
    40141 caggtaccta tgtttagtca ggatttagaa gcaagcaccc ctgagtcagt ggcaggcgta
    40201 cgagaagcca ttcaagcagc agatgctatc tggatttttt cacctgtcta taattttgca
    40261 atcccgggct ctatcaaaaa cctattagac tgggtatcac gcgcccttga tttgtcagac
    40321 ccatcaggac catcagcaat caatggtaag gtagttaccg tatcatctgt tgctaatggt
    40381 gggcacgagc agctatttgc gcaataccag gacctgctgc cctttatccg tacgacagta
    40441 gttggtaact ttaccaaagc cgctgtcaat ccagaagcat gggcgacagg tgttcttgat
    40501 atttctgagg aaacaaggca aagccttgca gcacaggcag aagcccttct tgaagccatt
    40561 cactaagact ctctgagcat taaacagata aagctgcagc taggatcaaa aagcagctag
    40621 acacataaaa agagcttaaa ccagaaatgt acggcactcc aaaagctaga caaaaactct
    40681 agcgattggg gtacaggtca aaacggtttt aagctctttt ttagacttat tttatagtag
    40741 taacttaatt aagaattagc ataccctctt tagcctcaaa ggggtttttc gcattaatac
    40801 ggtcatagaa taagacacca ttaatatgat caatctcatg ctgaaccacg atagcattgt
    40861 agccctttag cttaatgcgg tgcttttcat tgtgcttatc gtaatattcc actgtcacac
    40921 gcgcatgacg gacgacatag ccttccacca cacgatcaac agacaaacac ccctcaccgt
    40981 cagcaagagc agcgtcttga acagaatgag acacaatttt aggattatag agcacttcct
    41041 ccatgctgta agcctcctta ggtggattgc cctcgctgtc ttcaggattt ggaaccagaa
    41101 cagcgatgat acgctttgac acatcaatct gaggtgctgc tagaccaact cctgctcgaa
    41161 gccctaattt ttctcccatg acagggtctt gagaatgctt taaaaattgc atcatttttt
    41221 cacctaaaat gatgtcatca tcactaagag gaaactcgac ctccttagcc acagcacgaa
    41281 gcgtaggatt gccttcgcgg ataatatcat tcatatcaat gagatgctgt gctttaatta
    41341 atttatcttg tgcagacatt ttgcctccct ttttttatat ttgataatgg ctttactata
    41401 tcacaaaatc cttattttta aaagataagg caggccagtg atgacgatat tagctaactc
    41461 tatcagatat attaaattat ttaaaaaata gttcgttaat tagcacgaca tatatataag
    41521 aaatacacag gaattctaat aattaataga taaaaaatga taatcgttcg taaataaatc
    41581 aaacatctaa tctaaaaaaa ttatattgtt ctgattgttc ggtaattaaa gcaatagcgc
    41641 ttgtcgaaaa actaatgttc tcttaatatc aggtagccat gccaagggtt ttgtgttaaa
    41701 gtataggacg ttcaaaaaat gaaatggaga gactaatgag aacacaattg aaaaaattgc
    41761 tggcaggaac agcagcaggt accctgctgc tgtttaacct gacctgcgga atgattaatg
    41821 cttttgcaga gcagtattac gggtggagtg acgggagtag cagctatccg agtgctttgt
    41881 atgttacacc ggtaggagat actacgaaaa agatagctat tcctgtttat tgctttgact
    41941 ataagtttca ggagccactt gcttggaaag aaataactca accgtcacac ttgattgtct
    42001 atgataagta tgatggcaaa aatttgatgg cagcactggt tgaaaaacct aatatggtaa
    42061 gctatgagac taaaactaaa cttcaaacac ttttaaagac aaagtcaaat ctaataactg
    42121 caattttaag tagaggttat ccaaacaaaa gtttttttga taagtataaa aaattaactg
    42181 atgaagataa aagacgagtg acacaatgtg ctctttggta tcatactgac aatatttcag
    42241 aacaagatct tatcacaaaa catttggatg gggattcagg tgaaaaaagt caagcgctaa
    42301 aggagttaat aggggttgta aaaaatactt ctaatgagtt aggagaggga ttaaccttct
    42361 atactcgtta taatgataga tatggtccta aatatcaaaa cctaataggc tcaattattg
    42421 ttcccgaaga gcctcagaat gatcttgaaa ttggtggtgg aaatgttatt gatttaaact
    42481 accaatctgg accaatggta gaagaaggtg gtcattcagg tggcaaggaa gaggtcgagg
    42541 acactaaaaa gcctgatgtg attattggtg gtcagggaag cgttactgag actactgagg
    42601 atactcaaaa gggtatgagt ggcagtactg agactcagcc agaggttgag gatactaagc
    42661 agccacaatc agatattatc ctaggcggac aaggcaatgt gattgacaca actgaaaata
    42721 cccaagaggg catgggtggc caatcaggtg atactacaga gactgaggat accaagcagc
    42781 cacaatcaga cattatccta ggtggacagg gcaatgtaat tgacaccact gaaaatactc
    42841 aagagggtat gagtggttcc aacaatggtc aaacatttga ggaggacaca cgtcctaagc
    42901 tggaattcca ttttgataat gaagtgccta acgatgatga cgctcctaaa ccagagcaac
    42961 cagaacagcc agagaagccg gagcaaccaa ggaagccaca gcaggagcag caaagcctac
    43021 cacgtccaat agagggcaac cagtcattgc caaaaacaca tgaggcaaaa ggtgtactgg
    43081 ctctagtagg agtaggaatc cttgctatgc taggactagg cttttggttt agaccttatc
    43141 aaaaagacta aatcaaggct cagcagctat ttaagctaaa cagctgtgct cagctaaatg
    43201 ataaaacaat taagattgga gaatgtggct attagtagct tctccaatct tttttgatag
    43261 cagcatgtgc tttttctgcc gtattttatt gagaataata gttgaccagt ctaggcgatt
    43321 ttgctagaat agagaggtcg caagacagac taactttttc ttggttttag gagtgccaac
    43381 cctaaaactc ggattaagca aaaaaggaga attattatgg caatctcaaa agagaaaaaa
    43441 aatgaaatta ttgcacaata tgcacgtcac gaaggtgaca caggctcagt tgaggttcag
    43501 gtagctgtcc ttacttggga aatcaaccac ttgaacaacc acatcaagga gcacaaaaaa
    43561 gaccacgcaa cttatcgtgg attgatgaaa aaaatcggac accgtcgtaa cctattagca
    43621 tacctacgtc gtacagatgt taaccgttac cgcgagttaa tccaatcact tggacttcgt
    43681 cgttaattgg cttgacagag gtcattttag agataaccaa gttctattga aaaaagatct
    43741 gct
//
LOCUS       DARYMD010000014        41239 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYMD010000014 DARYMD010000000
VERSION     DARYMD010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41239
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            398..811
                     /locus_tag="TU818_000664"
     CDS             398..811
                     /locus_tag="TU818_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0923506.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAISLMAVLLSKDIHRLSLGSLI
                     SFAIFAVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
     gene            1071..1652
                     /locus_tag="TU818_000665"
     CDS             1071..1652
                     /locus_tag="TU818_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL0923507.1"
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVTFEYTVPSLTEFERRL
                     SDIMVFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            2062..2388
                     /locus_tag="TU818_000666"
                     /pseudo
     CDS             2062..2388
                     /locus_tag="TU818_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin, lactococcin 972 family protein"
     gene            2457..4460
                     /locus_tag="TU818_000667"
     CDS             2457..4460
                     /locus_tag="TU818_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923508.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTVYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTERGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRKELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKQATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDKAKDFAEITWLDTLSTHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDNDVIYSALSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAVGVIYISKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPDGQKSFLFNHKQDQQDIFAQQEEVNTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            4457..5065
                     /locus_tag="TU818_000668"
     CDS             4457..5065
                     /locus_tag="TU818_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0923509.1"
                     /translation="MIEIKQLSKHYGKKTIYDKLSLTFEANRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGQDIWSMKEQDYFKDYLGYVFQNYALIEEETVYDNLKMLAP
                     KSNIVEALHSVGLDSSFLSQNIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(5254..7980)
                     /locus_tag="TU818_000669"
     CDS             complement(5254..7980)
                     /locus_tag="TU818_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL0923510.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPGREAEIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCEQWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKKARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYDFVHSCFEDYLADLSQELPEEL
                     SIVSGEMTSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLATMAFEVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKIFPFGQRLPKAVYQEAKEYLETRQP
                     QFQVIDAAGRIIEEAEILGTDIAFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQATDTDKMLFHQDRSCLENDFLKVIIAANGLLTIEDKLNGNRFDSCLQY
                     EDCGDIGNEYIFRQPDHDSPYLAHQGSCKLRVLTNTAYLAEIELTQTFDIPLATDDRL
                     KAEMEAVIDIRERQAKRSQEKAPFTVTTVIRMEKDSPRLQFQTSFNNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPTNPQHQEAFVSLFDGRTGVTVGNYGL
                     NEYEILPDTNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQVPVTMAQTKRHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDKACALTLAIPDHTARVTSLLEEDQHEPLPAELGKGEILTLAWKKSESAHL"
     gene            complement(7995..9281)
                     /locus_tag="TU818_000670"
     CDS             complement(7995..9281)
                     /locus_tag="TU818_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL0923511.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     IDEDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDAGMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETDCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSQGEIIYAYEVDGLGHYTIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSPENP
                     YYYQGSAASGIGSSHTPPNYIWHIALALQGLTALDQKDKADILDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
     gene            9414..10472
                     /locus_tag="TU818_000671"
     CDS             9414..10472
                     /locus_tag="TU818_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0923512.1"
                     /translation="MTELLYKKIYHFIKEQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TVVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATAEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIERLTRPDQQTASCQ
                     LPVKVFIRESSQKSLEML"
     gene            10487..12181
                     /locus_tag="TU818_000672"
     CDS             10487..12181
                     /locus_tag="TU818_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL0923513.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLTASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFRDLIQLAKERQVDFWYMISPGLDFDYTKE
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYQIVAAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDKAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALMRKDIASLSGWVAELVELVDKLKELDIPAFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYAELQEQRHRIGSNIPSRFYQLHYLQENSMLGNQAQVAEARAEDYT"
     gene            12208..13599
                     /locus_tag="TU818_000673"
                     /pseudo
     CDS             12208..13599
                     /locus_tag="TU818_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            13586..13723
                     /locus_tag="TU818_000674"
     CDS             13586..13723
                     /locus_tag="TU818_000674"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923514.1"
                     /translation="MELAKKRRKTQKPAQSPLKLGLEKLREILQEQLVALAVLPARVM
                     G"
     gene            complement(13919..16093)
                     /locus_tag="TU818_000675"
     CDS             complement(13919..16093)
                     /locus_tag="TU818_000675"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL0923515.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     ILGCVQNITDCQDKDLAMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEYSRKEWLSYLSRIDIKDKDFDKV
                     KAYYQHFYRALLFPQRWYEITATGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAALLGKTALSDQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGNAAIAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCRGNVPQYQFVKEVKLNQA
                     SYNKLYINHDDLIQGCQLDFQLGLVPPLKHYSAEDLPYSLTR"
     gene            complement(16081..16974)
                     /locus_tag="TU818_000676"
     CDS             complement(16081..16974)
                     /locus_tag="TU818_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL0923516.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQIINDGKSYTGKEVLELADQGDPVALKERQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            17186..18136
                     /locus_tag="TU818_000677"
     CDS             17186..18136
                     /locus_tag="TU818_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0923517.1"
                     /translation="MTTKISSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            18146..19072
                     /locus_tag="TU818_000678"
     CDS             18146..19072
                     /locus_tag="TU818_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL0923518.1"
                     /translation="MEKKKTVKRVNVRTFDPKTNAVFNVLIALFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            19156..20601
                     /locus_tag="TU818_000679"
     CDS             19156..20601
                     /locus_tag="TU818_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0923519.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATLDLQYIGWGDWDDKMRIIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEKVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSKISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            20949..21554
                     /locus_tag="TU818_000680"
     CDS             20949..21554
                     /locus_tag="TU818_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL0923520.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNARQFLLTLVVLAGV
                     AWFTWQYKGLYLFLSFGALVLLLDMVTKPNRRMVDGVIDDK"
     gene            21544..23268
                     /locus_tag="TU818_000681"
     CDS             21544..23268
                     /locus_tag="TU818_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0923521.1"
                     /translation="MTSKSLKRFLMEHIKQGFLINRLMKIYSLFIVALFSLSAVGLST
                     YSIRNTYQMVDNQMQMRLDETLARLQSQNYITLRVLEQLIGRPEDYRNLYQYMILTPN
                     QYLTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTSYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGRLYLHFASPSTMLQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIRQVSEITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYILEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFAALLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEIPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEEDSILIQVLDN
                     GKGISPERLVAIEKGLEEPQSTGNSSIGLQNVYMRLFHKYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            23268..24752
                     /locus_tag="TU818_000682"
     CDS             23268..24752
                     /locus_tag="TU818_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0923522.1"
                     /translation="MYKVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPEAELLGFTVLYVDCKTFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSFFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKTLMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRTTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQRFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            24766..28209
                     /locus_tag="TU818_000683"
     CDS             24766..28209
                     /locus_tag="TU818_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL0923523.1"
                     /translation="MSVETITGSTDQSHGDIYQLHWIDKVGRCHAFSKGWRFLMADLQ
                     LAQEPFFDDSDWQQIALPHDFSINQPYTVNGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHLVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEADSQALEIELGLSQQVPLSG
                     YQLSLSLFEQLADIQQRQTVYESKPVALDLLEESGRLVMTIPLRHIKLWSPAQPQLYQ
                     LDMLLYHKGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAY
                     EEAIARQLVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSH
                     DFSSHFHKTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPSVLMWSIGNELLEG
                     FSADVSHYPYVAKELCQWITELDQSRPITLGDNKLKDKHFHWAQETKALAEQVNQLQS
                     VQGVIGLNYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYD
                     QSTVDWGSLASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQS
                     YFGILDTAGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAAS
                     VRILFDDGHGGQIDYGIKTLTRHETPAGHCYQLYEGDDAAELPHQNLYLTWKLPYRSG
                     SLRAIAYDDKGQVLTQTSGRSCVSSYQQPAQLSWSCFEPPKLLAEPALLYLELSLLDA
                     NETLVLSANPVIKLEVEGPGACLALDNGDPRDHRPYTALSRRAYGGKLLAIIALDGRA
                     GQLRITARAAGFVEASYQLTVSEAAVNEKLLAYQLDKYSFITNETNKPSKPYARSRGS
                     AVDSLMPNPDSCLKRQGHYLPDNSVMVFSYTTALSRPLTFQPLIKRLLKGNDIILPDW
                     LQPRAAAGQLFTKAFPIDWQLTEAVFSEESRVSGQTLCFGEALELEAILKSDTKGLRI
                     NQELSLVAKKKRLFQSDTQLSYRYQYDTIQAIGAISLTGLKKPLSSLRLVLDYRSSTN
                     APSKQLILSLDQIEQPCHYIMLEEVVDVLSLDLTLEQPIRQAFDLARLQLGLWSMVEE
                     A"
     gene            28360..29244
                     /locus_tag="TU818_000684"
     CDS             28360..29244
                     /locus_tag="TU818_000684"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL0923524.1"
                     /translation="MLERLSGQTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVGNAELAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNKDGR
                     GHLVGHITDGTGAIRALAEEGVSIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQLVARINTQTSALASLQDLADDRAFRRSISESSIYIDATGVGMKPFEEH
                     RLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCQNKE"
     gene            29370..30143
                     /locus_tag="TU818_000685"
     CDS             29370..30143
                     /locus_tag="TU818_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL0923525.1"
                     /translation="MILTQFDPDYQAIINPKDLVAEIDDFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(30475..31557)
                     /locus_tag="TU818_000686"
     CDS             complement(30475..31557)
                     /locus_tag="TU818_000686"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL0923526.1"
                     /translation="MTQTLQVKSRINDYPIIFTDDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEVSRIYDRLIRANFSKKDVIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYVSFPIAKHDSRLLDWLRSLLDIA"
     gene            complement(31616..32371)
                     /locus_tag="TU818_000687"
     CDS             complement(31616..32371)
                     /locus_tag="TU818_000687"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL0923527.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGY
                     RYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            32809..32979
                     /locus_tag="TU818_000688"
     CDS             32809..32979
                     /locus_tag="TU818_000688"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923528.1"
                     /translation="MLRYLKAILYLLAPRLAFSVTGVLFPDVFDNLFLVYNILMTLAF
                     WLAIYSVDLPEK"
     gene            33886..33956
                     /locus_tag="TU818_000689"
     tRNA            33886..33956
                     /locus_tag="TU818_000689"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33918..33920,aa:Thr,seq:ggt)
     gene            34484..34738
                     /locus_tag="TU818_000690"
     CDS             34484..34738
                     /locus_tag="TU818_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL0923529.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSRQIAKEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            34760..35260
                     /locus_tag="TU818_000691"
     CDS             34760..35260
                     /locus_tag="TU818_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0923530.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAEKAAQPKADVASSSLADSSEVSSEKEASKASSEVL
                     SRDAFAELAEVSELRADIVTVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            35520..36104
                     /locus_tag="TU818_000692"
     CDS             35520..36104
                     /locus_tag="TU818_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0923531.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLADVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLDF
                     TLEATIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            36304..36867
                     /locus_tag="TU818_000693"
     CDS             36304..36867
                     /locus_tag="TU818_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL0923532.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELEIDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKVPENLKYY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            36880..39531
                     /locus_tag="TU818_000694"
     CDS             36880..39531
                     /locus_tag="TU818_000694"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL0923533.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSGDKKAKPYAIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDSAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGDMYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFQRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQASANVEQVASGAAGNVTDCWILHNLNETIGKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTADYPTVDPAFENEAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPERLKIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVSKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            39744..40232
                     /locus_tag="TU818_000695"
     CDS             39744..40232
                     /locus_tag="TU818_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL0923534.1"
                     /translation="MTTAATKASVPHKEKMESKEPETSHQPEAYPDLASYQELAVHVS
                     IADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFVIEPERGDFFFNQASEEGAYYWVS
                     FKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHGCVRMSRADAKWFYDNIPEGISVT
                     IE"
     gene            complement(40435..41217)
                     /locus_tag="TU818_000696"
     CDS             complement(40435..41217)
                     /locus_tag="TU818_000696"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923535.1"
                     /translation="MSLIVNLPLLSLICFNEVSANSDYENSPVLGQGYYGYDDYTEAP
                     QIGDQKVIGFRRDWENARDFGVKPIKNNDKEIVVKTSPGSLIRIFKVEEDDKETELVQ
                     VQKKSNGDLTNNRYYPIAKWDGKIVFSLESARTQKTNSKEETYVPYNKIASNGDKFRV
                     HITSDGFVLGSEIWIVGESKPQDIIEQEQKKAQKELEEQKKQENLRQQIKKEREHSQK
                     RVVENIYLKEIRENAHKSWHKRLNEKIQEQWSKFTVFLNKYY"
BASE COUNT        11344 a         8276 c         9597 g        12022 t
ORIGIN      
        1 gaaaggagtg ctttcaaatg ttatcagggg agcatgatgg ctaaagagag acctcagagg
       61 aaactcagtc tttgaagcat taagacagct ttctcatatt ggttacgggt attagaaatg
      121 cgcttaatcg gtgtcaacag ttttcgtatt accatttaag acgtttcgac gacattttaa
      181 gacttaaata ctgaaagcag ctggtaatat gctatactgg tgccagttgc taaacatagg
      241 aaatattcat gtggacgaca gcattgatga aatatttaat gcttaggtac tggtagactt
      301 gcttatgttg aggctgaaaa aattaataga gtttgtgacg cagctattgg aggaataggt
      361 ggcgcactga cttgctaaga aagggcaagg tgttgtaatg cttaataaaa tgaagcgact
      421 acattatttg atgattttta ggctattaac tggtcagcta ccagctatta gcttgatggc
      481 tgttcttctt tcaaaagaca ttcataggct ttctttggga tcactgatta gttttgctat
      541 ctttgcggta agcactgctg cttctaatta ctatttttca cgagaaattg cgattgagca
      601 gttgaaggaa caaacacgtc ccaatctgtt attaactcag atcctgttta tagtggtgtt
      661 tatgattata ggcattgtgt caatctattg tggtctaagc tcgtctgagt tttataagca
      721 ggttattgct gtgatatgct cttttatatc atttgtcact atgggattga tgatttgggg
      781 gatcagatac gcaaaagctt atcgtcgtta atagcttgag gtggtactgg tacttgaaat
      841 cacctcctta accagttaat cataagctat agcactaggt atcagcctta aagcgacgat
      901 acctagtgtt tgtgtgctca aacgcttaaa atagcttttg agggggtaga gctgtctatc
      961 tgcaagcgat atgacaacct atttcattta gggatcaggc ttttttacta tcagtgtttt
     1021 tgacaaggcc cttgttttgg agtatactgg gaaaactagg agggctatta atgcgtagga
     1081 ttcgtttagc aaccttagca gatgctaagg ctttacttga tatttaccgt ccttatgttg
     1141 aggaaaccgc tgttaccttc gagtacactg tacctagctt gaccgagttt gagcgacgtc
     1201 tgtctgacat tatggtcttt tatccctgtc tagtagtgga agaggaggga ggcattttag
     1261 gttatgccta tgctagtcgc tttcatgcac gcgcagccta tgcttggtct gctgaggtga
     1321 ccatttatct ggcccaggag gctagaggga gaggcttggg atcagccttg tatcaccgtt
     1381 tggagggtta tctgaaaggt atgggaatct taaattgtaa tgcctgtatc gctagtacag
     1441 cgcatgctac gccttatctg accaatagca gtcaagtctt ccatgaaaaa ctcggttatc
     1501 ggttggttgg cagatttcat cagtcgggct ataagtttaa ccagtggttt gatatgattt
     1561 ggatggagaa actgctggga gagcatgacg tacgccctcg cccagtgatg tcatttaggg
     1621 attttctttg ccagaagcac cagtctgaat gacaccttat aaaagcttag attaatacaa
     1681 aaggattagg tcctgtcaga ggaagctaat ttttttgtat tgtttgacga gaagttttga
     1741 ctgataaccg caatcataaa aaaactcttc aggccctgtt ataaaatggt ggtagcagga
     1801 gatggttatg tctgagcttg tcactaggtc agctacagca gtcctagtgt catagcttta
     1861 aaaatgagaa aaaagaaatt attttttaag cttggtcttt ttaatatctt tttttgccct
     1921 tgacaattct gccaatgagc tgcaaaaaaa cttaagctct ttcccaaaaa gcttttatga
     1981 tatgatacac ttgtgttgta aaaggatcct gatactagtt aagatttttt tactttattt
     2041 taacaaagga gagtacacga catgaaaaga agtgtaaaat ggtttatgag ccttggcttg
     2101 gttggagctt tcgtagttgc tgggatatct aatgttaacg cagagactag gcaccctcat
     2161 ccaaagtata aggacacttg ggaatttgga attaccagtg ctagctgatc ttactcaaac
     2221 gcttttcttg gagttcctat tgggctagga agtagtgctt ctgtgacaga cttttgggga
     2281 aatgtaaata gtaaagatag tcaaaacaat ggttgggctc gtgccggtgt aaaaaagcag
     2341 tggaattggg ttcaagcaaa gtcatgttat ggctggtatc aggtttaatg ttttattgta
     2401 cgttttagtg gatgaagata ttatcctctt agtcaacttt tctcaaggag gtttttatga
     2461 ggtggagagc tacagttatc tgtattttcg ttctgctttt gacatgttta tcatttggtg
     2521 cggtcaagga gtatggcaat gatatcaaat accctgttca ggctgcattt tcattagtgg
     2581 cttcaaacaa agatgttgat aagggacacg ttttagacag gatcgaagcc ttagccgagc
     2641 aggaacatat ccaaatttat cgtccctact tagatcatac tggtaaagaa gccacctacc
     2701 tgtttgggac aaatgggaaa aagactgtct atagcagtaa tcgcaaggag ctcttgacaa
     2761 acgatcttag tggcatgtac tacacgacga ggtctcttcc ttcatcattt gaaaccgcga
     2821 tgactgaacg gggcttgacc tacaaaggtg ctgatttacc ttggtatctc ttgccttatt
     2881 attttttgtt cacaaactta cgatccttag ctatttggac cctctttttt gtgtttgccc
     2941 tcctcttgtt tgctgttaaa ttgatgtatg ctaaaaagtc tatgatacta agaagcctgg
     3001 gcttatttga acactatagc cgcaaggagt tgctacagga tttgttgctg atgggagcta
     3061 gctttgcggt tagtattctc ctcttcattc tctatcaagg cagtatctcc aatgtttttg
     3121 tcaagtcatt tacacttctg atcttgacta atgctgtcat tttattattg ctgatgcttg
     3181 ctgttcatgc tttatttttc atcaatatcc gttcgttgaa ggcgctagcc attctaaaaa
     3241 ataaacaagc aacccctttg gtcctctttg tctggttggt ggggatttgt ttgtctagcg
     3301 tcatttttgg gctttcccta cacaaaagct tggagactat aggaaaatct gccaatgaca
     3361 ttcaagttct aggaaaatgg gataaagcta aggattttgc ggaaataaca tggctagata
     3421 ccttgagtac gcatactgat gacaatcacc aaattgatag tgattatttc aaggaagaaa
     3481 atcagcgcta tcaacatttt ctcctgtctt tttctgataa tgacgttatt tattcagcac
     3541 tttcaagcct taacgaaacc aatttacaat cagctcctga tgacttcaaa aaagagttaa
     3601 agaccaatgg ggttgatcca aggattgcgt caaaagtccg ttatgtcaat cagggattta
     3661 tgctaaaaaa taaagacatt ttccctaaca atgattacgg aaggccagca gctgatgctg
     3721 taggagtcat ttatatttct aaacatatga tgggagatgc tgacagcatt ttaaacattg
     3781 tcaattatga atggtttcaa tatagcagcc taaaggctaa tcaattggtt gttcaagagg
     3841 ttcctgacgg acaaaagagc tttctgttta atcataagca agaccaacaa gacatttttg
     3901 ctcagcaaga agaagtgaat actatattag tgcagttaaa cttttcgttc atgacggagc
     3961 catcattatt gacgaagttt ggagaaatgg ctcaaaaatc tatctatcgt caggcgctta
     4021 ttcgtgatcg attaacacaa gcaggcttga cgaatttctc tagtttgacc aatgtttcca
     4081 atcatttgat tttagagcgc cataaaatcc taagccagct catcggaagt gttattgcct
     4141 taacggtcct tgccattgcc cagtgcttta tcatttatga atacattgtt tctctgatga
     4201 aacaaaaggc caaaaagatt tccgtctggt tcttgatggg gcaaaaaagc cttgttttga
     4261 ttggtagatt gttattgccc ttagctttgt gtttgtttct tgccatagga atgatgggaa
     4321 tccttactgg aaataggctc atggtactag gcattggcct gctttattta ggagaaatcg
     4381 tttgtatgtc cttttttgct tatcaggcta ttttgaagca tcggattcaa atcatcaaag
     4441 gagattttga catattatga ttgagataaa acagctttcc aaacattatg gaaaaaagac
     4501 aatttatgac aagcttagct tgacttttga ggccaatcgt tcttatgcac ttgtaggtcc
     4561 ttcaggatca ggcaagacca ccctattaaa tgctattgct cgccttgaaa agccagatag
     4621 tggtcagatt ttagtaaatg gtcaagacat ttggagcatg aaagagcaag attattttaa
     4681 ggattatttg ggctatgttt ttcaaaatta tgcactgata gaggaagaaa cagtctatga
     4741 caatcttaaa atgctggctc ctaaatctaa cattgtggaa gccttgcata gcgttggctt
     4801 agacagtagt tttctctcac agaacattta tgaattatca ggtggtcagg ctcagcgtgt
     4861 tgctattgca cgcctattgt taaaaaaggc ttgcattatt ttggcagatg agccaacggg
     4921 tgccttggac aaggaaacag gtgatgagat tattgagctg ttgcttagtt tggtgagccc
     4981 tgatactgtt ctgatttttg ccactcatga cccaaatgtg tttagccgcg ttgatgacat
     5041 catcgacatc tgtcatctac aatagaggca agctctgaga catttagtct ggactgtcga
     5101 gctacagcaa ttagcttgac aatgctgtta ttcctttgtg tcaggaagag attgctattc
     5161 ttctatagat ttttcgaata gacaatgctg aaagtcctta gcgttaatgc taaggacttt
     5221 tttgtgattt aggtcaaggt agtggtaatc tggttataga tgagctgatt cactcttttt
     5281 ccaagctagg gttaggattt cgcccttgcc aagctcagct ggtaggggtt catgctgatc
     5341 ctcttctagt aggctggtaa cccttgctgt gtggtctggg attgctaggg taagagcgca
     5401 ggccttgtca tttgatacat tatagctgcg cgtgattagg gcattatcgg ataggcgacg
     5461 cttgaaggct gtgagagcaa cgtgatcagt tgctcctttg atgtaagcat attgagctgg
     5521 cagctggcca gaatgcctct tggtttgcgc catggtgact ggtacctgag cctcctgagc
     5581 tcgccaatag ctggcaaagc gtgtggtagc gttaatgctt tcaaagctaa agctgacagt
     5641 ctgttgaccg aggcattgag catcaggggt tgggaagtag ccccaatctc caagctcacc
     5701 gacgcttcgt aggagcgtga tagcgatggt attggtatct ggtaggattt cgtattcatt
     5761 gaggccgtaa ttgcctacag tgacaccagt cctaccatca aaaaggctga caaaggcctc
     5821 ctgatgctga ggattggttg ggtttttcca gaattgggca ttggtatgat taggccgctt
     5881 tacggtttca aaaatactat ctgcaaaatg gtggtctgtc tttaaatggg ttgggaatag
     5941 cacgcgcaag cggtggtttg tcatttgatt gttaaagctg gtctgaaatt gtaggcgtgg
     6001 gctgtctttt tccatacgaa taactgttgt tactgtaaag ggcgcttttt cctgtgagcg
     6061 tttggcctga cgctctctaa tgtcaatgac agcctccatt tcagccttta gacgatcatc
     6121 tgtagctaag ggaatatcaa aggtctgtgt caattcgatt tcagcaagat aggctgtgtt
     6181 ggtcaagacc cgcaacttac agctcccttg atgagcaagg taggggctat catgatctgg
     6241 ctggcgaaag atatattcgt taccaatatc accacaatcc tcgtattgga gacagctgtc
     6301 aaacctattg ccatttagct tgtcttcaat cgttagaagg ccatttgctg cgatgatgac
     6361 ttttaggaaa tcattttcaa gacagctcct gtcctgatga aagagcattt tgtcagtgtc
     6421 agttgcttgg caaggctgat cagtctcttt tagtgcaaga cattgccatg acatagcaga
     6481 aagagtcagt gggagcctta gctgtacctt gatggcaaag taggcttctc tgaaggtgcg
     6541 ctctggcagg gcataatcaa aggcgatgtc tgtgcctaag atttcagcct cctctatgat
     6601 cctgccagct gcgtcaataa cctgaaattg tggctgtctt gtctctaggt attcctttgc
     6661 ttcttgataa acagctttag gcagtcgttg cccaaatgga aaaatcttcc atgtcagggt
     6721 gaggtcggag accgtttttt tctcatgacc gcaggtattg aagaggacaa aaggacagct
     6781 atcctctgga aacatggagg tatcaatagc ctcagctatt tggttggcag aacgctctgc
     6841 taagtaagtc cccacctcat aggctttatc aaagcgaggc atcatctcct ggtggacact
     6901 atcaacacta cagccacaaa tggagtcatg agggtggttt tgcatcaatg ttttccaagc
     6961 atagcgcagc tggtcgtgag gataggtacc tgtgacctca aaggccatcg tggcaagagg
     7021 ctctgtgata ttttcaagct gacgagacac tctggtatta gcctgcttga ggtaaattct
     7081 agcagaggca gtgttggcta aggtatacca gccgtccgtt tcttggctgg tcatctcacc
     7141 agacacaatt gagagctcct caggcagctc ctgacttaaa tcagccaaat agtcctcaaa
     7201 gcaagagtgg acaaagtcgt aatcagggta gagcttattt gcaagggcaa ttgccttggt
     7261 aacgtctagt tgaacaggct ggtgatcaac cccattcatc atcagcaggt gcctggtaga
     7321 agcaaagcgc tcagcgtctg ctagcttttg atcccagaat tgtcgagcct ttttctcctc
     7381 ggttgggatt tcgttgccat tgctgtacca attggcaaat aataagccga gaatgcggct
     7441 atcatcaggt ccctgccaga tcatttcaga aaattgggag ctgtattttt cgcttgtatc
     7501 cacttgattg ttaaagcctg taggcctgat accacgtcca aaggcagcgg catttagccc
     7561 tgcttttcgc attagctgtg gtgtttgtcc catatttccg aaggtgtctg gaaaataacc
     7621 cagtggaacg cttgcccccc attgctcaca gtcctctttg ccaaccagca tgtttcggac
     7681 attggactca ctgctggtca aaaaggcgtc ctgtaggata taaaaggggc caatacgtag
     7741 cttaccagcc tgaatggcct gtctaatctc ggcctcacgc ccaggcttga cctgcaaata
     7801 gtcatctagg ataatggttt gcccatctag atggaagcta tgaaaatcag ggtctgtttt
     7861 aaaaaggtct agtaaatcgt caattaactg gatcaagcgc atgtggtgct gctcataagc
     7921 catgtaccat tcgcgatccc aatggctgtg tgaaatgata tgtacttttt taggtgtcat
     7981 cactgactca ctttctaagg gctaatggta aagcccagat aatcaagaag aagctcacaa
     8041 aacatcatgt ttgcccatga gaaccattca cgtgtatagt gactcggatc attgacgtca
     8101 aagccctcat gcatcaggtg ggtgcctgcg tcagtagcca ccagtaaatc aagtatatct
     8161 gctttatctt tttgatcaag tgcagttaag ccctgaaggg caagtgcaat atgccaaata
     8221 tagtttggtg gcgtgtggga ggagccaata ccagaagcag cactgccttg gtaataataa
     8281 ggattttccg ggcttaaaat ggtttgacga gtggctaggt aaatagggtc gtccttggca
     8341 caaaagccaa gatagggtgc cgcaaggagg cttggaatgt tagcgtcgtc catgatagta
     8401 tagtgcccca ggccatctac ctcataggca tagatgatct ctccttggct gttggttaca
     8461 agagcatgct cctcaatccc tttttgaatg gcaagcctaa gtgcatgagc tctcctagca
     8521 atcgtttgat ccttaaagag atcagtatag agcccttcaa gataggataa gacgacagca
     8581 gcaaacatgt tggacggcac gaggtagccg tattggcagg catcatcgct tggtctaaag
     8641 ccagaccaag tcatgcctgt ataggcaaca ggagctccct taccgttgtg ggtcaaggta
     8701 tcctccttac gccaggtgtc gcgctcaaag ctgtaaggag aggcagtgtg gtcttgctct
     8761 gtgctccaga catcaaggat cagcttgatt cctctgtgga aatcctcatt gaaatgctct
     8821 gtacagtctg tctctcggta gagcagatag gctaactgga tcggatagca gagggaatca
     8881 atctcatatt ttcgttccca aatccaaggt cccatctggg tgtggtctgc ttggtggccc
     8941 ttgctatttt cctcctcgtt aaaggcgttg gcataggggt caatgcaaat gtaacggaac
     9001 tgacgtttaa cgagacctgc tatgatttgt ctcatgccag catctgtctt ggctaaaaag
     9061 agataaggct ttagttgcgc agttgaatca cgcagccaca tggcaggaat atcacccgtt
     9121 agaagaaagc tggtcccatc ttcgtcgatt tttagggtcg tttccaaggt gttggcaaag
     9181 ctggctttaa aattaatggc ccagctacgg tgctcttcac cgcagagctc ttcaatcgtg
     9241 tccataaacc tgagcacact gctaggaata ggtcttgtca tatcatatcc tcctaaaaga
     9301 tatatcattt gatatctttt ttaattataa gatataactt tatttttgtc taccacttta
     9361 gaaaaggttt acaagtcttt tttttcgtga tatactgcta gagggagtaa aaaatgactg
     9421 aattactata taaaaagata tatcatttta tcaaggaaca aattgattca gggcaattac
     9481 aggcaggtga ccgcctacca acagaaaagg ccctatcaga gcaattttcg gtgagccgca
     9541 ttacctctaa gcgagcctta gtagagctgg agcaagaggg cttgattaca cgcagcagag
     9601 gtaagggcag ctttgtgacc gatggcccac caccgtctac tcagcctaat aaggacattt
     9661 tgttgatcct gccctttgct tctgattacg aattgggaga ttatgctaaa ggaatcatga
     9721 cggtcgttgc tgacaaaggc tatcgcctga tggtccagct tacaagtacg gtaagcttgg
     9781 aggagctagc tgattatgct ggtgtgattt attatccaga agacgttaat catagtattg
     9841 agctgctctt ttattgtgcc cagcgtgggc ttgctctggt gcttttggat aaggccttag
     9901 acctgtttga ctttccagca gttgttgcag acaataaggg cggagcctat gagttgacca
     9961 agcatttgat tgatcaggat tgccgtcgga tcatgtttgt ggcaactgct tcctttggtg
    10021 aggtttcctc tgttagagat cgttatttgg gttatttggc tgcgatggcg gaaacagagc
    10081 ttgaggccaa ttattttgtg aagctgaagt cagaaagcaa tgctgcttat cttgagcgat
    10141 tggttgatga gctgacggct gctacagctg aaaagactgg tttagtggtt gaaaatgatt
    10201 ggctagccat tcaattgatc caaaaaattc tacaggtcgg gctatctatt cctgatcagg
    10261 tagctgttgt tggctttgac aacagccaag cctctcagtt aatcagccct caattgacaa
    10321 cagctgcaca ggatttttac cagatggggc agcaagcagc gcaactattg atagagcggc
    10381 tgactcggcc tgatcagcag acggcgtctt gtcagcttcc tgttaaggtc tttatcagag
    10441 aaagcagtca aaagtcccta gaaatgctat aaaaaggaga agtgtcatgt ctatttatca
    10501 agccctcaag gactatcagg aggtgataac cagaggtgat tacctcgttt ttgacgcccc
    10561 tgtttcctgt cgctttgttg gtcgtttttt ccgatttgag aaccaaacag ctatgaagcc
    10621 tagtcttaca gcgtcagtct atgtcaactg ggttgaggag ggagcagctg acttgaccct
    10681 taagcacgtt tttaaccgca ccttagctag ggatgccttt accttgacca tttcagagga
    10741 taaggagctt gtgattgaaa gccaaaattt aagaggcttt cgctatgctc aggaggcttt
    10801 agaaaaggta atgactgtta aagagggcag gctttatttg ccgattgttt cggttaggca
    10861 tagtccgtcc tttgccatgc gtggtgtgat tgaaggcttt tatggcaccc cttggacgcg
    10921 tgaggagcgt ttagattgct tgagctttat tgctgataag ggcatgaata cctacatgta
    10981 tgcccctaaa aatgatgact atcagcgcag ccactggcgt gagccctatc cagaggattg
    11041 ggtggctcat tttagggatc tgatccagct tgccaaggaa agacaggttg acttttggta
    11101 catgattagt ccggggcttg attttgacta caccaaggaa gaggactatc agctgctcta
    11161 tcaaaaattg cagcaattgt tggatttggg tgtttgtcat tttggcctgc tgcttgatga
    11221 tattgattac caaatagtgg cagcagttga gagacgtttc aaaaaaacag cctatgccca
    11281 agcacatttg gcaacagctg tttaccagtt tttacagcgg cagcatgcag cccctgactt
    11341 ggttgtctgt ccgacagagt atgataatca tcatgactct ctttatttag cagagttatc
    11401 agaggctatt cctgctgagg tggctttttt ctggactggc ccaagcactc tggccagtca
    11461 gatttctcag gcagatattg agacaatagc agccatctac cggcggccca taatcatctg
    11521 ggataatatc cctgtcaatg attatcagga cgattctaag aggctctttt tgaccccgtt
    11581 tgccaatcgc tctcctttct tgtgtcagcc agactatcag gtcaggggga ttgtgtctaa
    11641 tccaatgatt agctgggaac tatcaaagcc gactttaatt gatatgagtc gctacctgtg
    11701 ggacgccaag cgttatcagc caagctattc ttggctagag gccttgagag actatactgg
    11761 agataaggct atggctttag cgcttttgcg ctttgcttgg cataatggca atcgtcattt
    11821 gcacagggat ctcccctttg aggtggagga ggcccttatg cgtaaggaca tagctagctt
    11881 atctggttgg gtagctgagc tggtagagct ggtggataag ctgaaagagc ttgatattcc
    11941 tgcgtttcaa caggctattg ctccttggtt tgatcgggct aaggctgatc agagcttttg
    12001 gagggttatt ttagagcaag cgcctgatct tgagcagcaa tatgctgagc ttcaggagca
    12061 aaggcatcga attggaagca atattccaag ccgcttttat cagttgcact atcttcagga
    12121 gaatagcatg ctaggcaatc aggcacaggt cgctgaagct agagctgagg attatactta
    12181 attagtttat aagggagaac aagggacatg ctagagtttc cagaaggatt ttggtgggga
    12241 agtgctacat caggccctca aagtgaaggc tgctttcaaa agccgcatcg caatttattt
    12301 gattattggt atgagcaaaa tcctgagctg ttttatgatt atgttggacc tgatacggct
    12361 tctgattttt ttcatcagta tgatcaagac ctagctttat tagcgtcttt gggtcacaat
    12421 tcctatcgga cctctatcca gtggacacgc ttaattgatg attttgagac agccacgatc
    12481 aatcccgatg gactggctta ctataacagg gtgattgatg cctgcctagc acatggtatg
    12541 cgtccggtga tcaatttgca ccattttgat ttgccaattg ctctttatta gaaatatggc
    12601 ggttgggaat caaagcatgt tgtggatttg tttgttgcct ttgctagagt atgctttgag
    12661 cagtttggcg atcgcgttaa ggattggttt gtacacaatg agcccatggt tgtggtggag
    12721 ggctcatacc tgctgcaatt ccactaccct gccattgttg atgggaaaaa agcggtacag
    12781 gtggcttata atctagcact tgcaacggct aaggttatct gtacctacca agaacaagca
    12841 gcagagctga gcaatggcag tgttggtacc attctcaatc tgacaccgat ctatccggca
    12901 actgattcag aggctgatct tgctgctgct catgttgcag agctgtggca caatgacctc
    12961 tttatgtctg ctgctgttta cggtagcttt ccaaaggagc tggtagcaat actacaaaga
    13021 gatggagtgc tctggcagtc cacaccagag gagctggatc ttatggctgc ttatacggtt
    13081 gattacgtgg gcattaattt ttaccgccct aagcgcgtga aggcgccaga ggttattcct
    13141 gtgattagcc cttcctggag tcctgagtgg tattatgatg cctatctgat gccgcagcgt
    13201 cgtatgaatg tggacaaggg ctgggagatt tatccagagg cggtctatga tattgctcta
    13261 aaaatgcgtg atcagtatag gaatatccct tggtttttat ctgaaaatgg ggttgggatt
    13321 tcaggagagg atcgttaccg agatgagagc ggacagattc aagacgacta tcgcattcag
    13381 tttttaaaag agcacctgac ctatcttcat aaggggattc aagcgggctc taattgcttt
    13441 ggctatcatg tttggacacc tattaattgc tggtcttggc taaatgccta taaaaaccgt
    13501 tatggtctgg tagaaaataa tcaccgcact cagcgtcggc gtgtgaaaaa atcagggtat
    13561 tggtttaagg aggtggcaga ggcaaatgga attagctaag aaaagaagaa aaacacaaaa
    13621 gccagcccaa tctcctttaa agctaggttt agagaagcta agagagattt tacaggagca
    13681 gctagtagct ttagcggttt tacctgctag ggtgatgggt tagcataagg gcttgctgat
    13741 gagctatgcc agtgatagcg attaaggaat gtaaaagagg atttcctaac atcataacta
    13801 tccgtctaac gggtgattta ttgtttcgta cctacggagc gaaacggact aaagtcacat
    13861 aactaaaagc atgtcatggc ttgctgtagt acgagtgatg acatgctttt tttagctttt
    13921 aacgggttag ggagtagggc aggtcctcag ccgaatagtg cttgagtggg ggaactagtc
    13981 ccagctgaaa gtcgagctga cagccctgaa tcagatcatc atgattgatg tagagcttgt
    14041 tgtagctagc ctgattgagc ttgacctctt tgacaaattg gtattgaggg acattgcccc
    14101 tacagctgat ttggatagta ttgccatttg gcagataaag ggttgcctga tctacagttg
    14161 gaataccaat caggtattgc ccagttcctg gtgtaacagg gtaaaggcca aggctgttta
    14221 acaggtacca cgcgctcata ctgccattgt cctcatctcc tgggtagcct gtatcggtaa
    14281 aggcatgact gagcagattt ttaaggatta gctgactgta ttgtggctga ccgatatagt
    14341 gatagagata ggggaggtga aagcttggct gatttgagat agcaatctga ccaaaatcct
    14401 gtgcggctag ctcactcatt tcgtggattt caaagccata gctgtgaacg tcaaacacag
    14461 gctcatgatt gcacagctcc tcaagtcttt tggcaatggc ggcgtttcct ccgatcagtc
    14521 gaatgtaacc tagaatatca tgataaaagg caaatccatt ttgataatag gagccctcgg
    14581 tgtagtcctg cccccagtgg atagggttaa agccacattg ccattgccct tgtcgatcct
    14641 tgcttttgag gtagccggta tcagtatcga ccaaatggcg gtaattgagt gatcgcgtgt
    14701 ggtattggtc actaagtgct gtcttgccca gaagggcagc tacctggccg atacaaaaat
    14761 cactataagc ataatcttga gtctgattga cgctttcctg gtagctattt ggcagatagc
    14821 ctagctcttg atagtcttga ttgcccttgc ggccatagcc tgttccttga ctgtctgtat
    14881 tggcagttgc cagcatagcc tctaaaagct caggcatcag gtcttttctg atgcctttga
    14941 cagctccatc agcaataaca gcatcaacca aggttccagg catcaggcct cgctcatctg
    15001 gagacagcca ttttggcaga tagttggtgt cctgataagc tgacaagagt ccctctaaaa
    15061 tatcagcata aatctcaggt gcaattagag acagcaaagg atagacagat ttataagtat
    15121 cccaaaagcc attgttggta tagtattttc cagcaacagg tctttgactt gttgtattat
    15181 agtgaatcgc ctgcccggtt gcagtgattt cataccatct ttggggaaat agcagggctc
    15241 ggtaaaaatg ctggtagtag gccttgacct tatcaaagtc tttatcctta atgtcaatac
    15301 gactgaggta gctgagccac tccttgcggc tgtattcaag gcttttttca aatgatctgg
    15361 ggaaatccct ctgccaattg agctgagctt gatcaaagct aataaaagaa gcagccgccc
    15421 taagctcaag atgtttgagg tcatcagcaa attggagata ggtaaaggac gtcttgctgc
    15481 aatcatcaag agatttggag tttaagtctt ctccgataag cttttttagc acagggctgc
    15541 taaactgaag ataaacaaac atggctaggt ctttatcctg acagtctgtg atgttttgca
    15601 cacagccaag gattgtttta ccatcagctg tcacctgcca ggagcttttt ccggggttat
    15661 ggataatcaa gcctgctttg ccattatcaa aggaaaaatc acaatgaaag ctgtaggcag
    15721 ctgctgttgc tcgcgtcaaa atccgatgtc tctggctaaa aatctcaaga agatgaggcc
    15781 gaaaagctgc ctccttggga cgataggagg tctgattatg aaacacatct cccttggtca
    15841 gcggtccgct gactggaaga aaagtaaccg tcgcaaaatc accgacccaa gggctgggtt
    15901 gatgtgtcaa gcgaatacct gaaaagctgt gatcatcggg gtgaaaccac caagcccctc
    15961 gatcttgact ggtttcgacg cttagataat gcatgccaaa gggaacccct gtcaatggca
    16021 ggcaatttcc ctgtgaaaaa tggtagtgat tggttgttcc aaagcgggtg tcaatgaagt
    16081 ctaatcgatc cacatctcgt cctttctatg ctcttgcata aaatcaatag aggcacctag
    16141 taggttggcc tcgtttttaa agtggcagat agcaagctgc ggtctcaaat cagaaatgct
    16201 gactatctga tagagcttat ccagttcagc ctcaagggca ggaagaagaa agtcagcctg
    16261 agagacaccg ccaccaatta ggatcatttc aggatcaaag gcatgctgga tattaaacac
    16321 ccccattgcc agactttgaa gaaagacctg tctttccttt agggccacag gatctccttg
    16381 atcagctagc tctaagacct ctttaccggt gtaactttta ccatcattta tgatctgact
    16441 atagcgcttg gccatattga ccacagtgcc taattcgctg aaggtttgat aacgctcatt
    16501 catgaccata aagccaaact cacctccaaa taaatgggca ccgtaatgaa tcctgccatt
    16561 aatcactagg ctacctccaa caccggtgcc aagtaccagc atggcaaggc tgctagtgcc
    16621 ttgtcctgca cctagagcag attcggcaag agcagcacag ttggcatcat tttcaatcga
    16681 aaccggcaga cctagtcgct cctcaaggca ttgctgaatg ggaaagccat gaatataagg
    16741 cagtgcactt gctccctcga tgatacctgt tgctttattg acagctccag gggagctaat
    16801 ggcaattcct gagagctttt ctgtgcggta gtaagccagt cgctcgtcaa gcatatggta
    16861 aaagtcctct aggctttggg gagttgggcg actgctttgc ttttttagcc tgcccttgtg
    16921 acaaatagca aatttgatgc tggtgccgcc tatgtcgata cataataagg tcattgtaat
    16981 tcctcctata acaggtatat taccaattag ctacccttag tatgacagat tttgaagtgc
    17041 ttgaaaagac tttctcggca ttcctatatt ttgtgctatg atacctataa tttgtgttat
    17101 caaacctata atttgttgct tgttctatgt gtaagcgctt gatatacttg aagcatcaat
    17161 tgaaaagcaa agggaggttg ggaagatgac gacaaagatc agcagcaaga aatccttttg
    17221 gaaaaatgtg atcaaatacc gcgctttgtt gctgatggta ttaccgggat ttgtctggtt
    17281 catctttttc ttttacattc cagtattagc taatgtagtg gcttttaagg attttcatta
    17341 ctcagcagga ggttttatgg aaagcctgaa agaaagtccc tgggttggct tagataactt
    17401 taaatacctt tttgcctcta aggatgcttg gttgattacg cgaaatacca ttgcttataa
    17461 tcttattttt ttactattta acgtcttttt tgccatcgct ttcgctatta tcatgagtga
    17521 gcttcgaaac aagaaggctg ttaaggtcta tcataccatg tccttactgc cttatttctt
    17581 atcatgggtt gtgattgagt attttgtttc tgccttttta aatacggata agggctttat
    17641 taatcagctg ctcattgata gcggcaatag cccaatcaaa tggtattcca atcccacctg
    17701 gtggcccttg attttacttt tcatgagtgt ttggaaagga cttggctaca acagtatcat
    17761 ttattacgca tcggttaagg gaatatcaga cacctactat gaggcggcta tggttgatgg
    17821 tgccagtaag tggcagcaaa ttagacatat caccattcca cagcttttgc cgatgatgtc
    17881 tatcctattg attattaata ttgggagtat cttcaaatct gactttggct tgttttatgt
    17941 gattcctaaa aattcaggtc ctctttacga tgttaccagt gttttagata cctatgtcta
    18001 caatgccctg acagctactg gtgatattag tatggcttct gcggccagtc tttatcaatc
    18061 tgtggtcgga acctgtatcc tgctcatcac caatgctttt gttcgtcgta tggatcccga
    18121 tgcagcctta ttttaggagg aggacatgga gaaaaagaaa actgttaaaa gggtcaacgt
    18181 cagaaccttt gacccaaaaa ccaatgctgt ctttaatgtg ttaatcgctc tttttgccat
    18241 ctcttgtatc attcctttta tctttgtgat gattatttcc ttcacagatg aaagctatct
    18301 gatcaatcat ggctatagct ttttcccagc tgcttggtcg acaaaggctt atcattatat
    18361 tttccaaggg gctatgtctc atcggatcat aagatcgttt gcggtgtctg tatttatcac
    18421 cgttttagga acctttatca ataccacaat gacctcaacc tatgcttatg ccatctcaag
    18481 accttatttt ccctacaggc gtttttttac catctatgcc ttgatcacca tgctttttgc
    18541 accgggtatg gtagccaatt atttggtggt gagtaacctg ctgcaattaa aggatacggt
    18601 ttgggccttg attttaccga tggctctggg accctttggc attttggtga tgaggacctt
    18661 ctttaaaaag accgttcctg atagtattat tgaatccgct cgtatggacg gcgcaggtga
    18721 attgatgatt tttatgaaaa tcgttttacc tttggcagtt cctgggattg caaccattag
    18781 cctgttctca gccttaacct attggaatga ttggttcaat gcgctgctct atgtgcaaag
    18841 cgagagcctt tacccgatgc aatacctctt gatgaagatt caaagcaata tacaggcact
    18901 agcccaaaat gctggcatga gcgcccagct atctgatagc ttagcctctt taccaaagga
    18961 atctgtccgc atggctattg ttgtcattgc aactttgccg atcgccctaa cctatccttt
    19021 ctttcaaaaa tactttgttg gaggactaac catcggcggg gttaaggaat aatcacccat
    19081 ttggaatagg tcatacagct gaccgttcca atgattctgt tatcaaaaaa agaaattatt
    19141 ttaggaggct tactgatgaa aaagtggcaa acaatcttat gtgtgacggg agctgtgctt
    19201 gcagctgcta gcttgacagc ctgtggaagc aaatcagctt ctaaggacgg tgaggtgaag
    19261 ctattgatgt atcaggtggg agataagcct gataactttg atgagctgat gacaattgca
    19321 aataaacgta ttaaggaaaa aacaggggca acccttgatt tgcaatacat tggctggggt
    19381 gattgggacg acaagatgag gatcattatt gcgtcaggtg aaaattacga cattgccttt
    19441 gccaacaatt atgtggtcaa tgctcaaaag ggtgcctttg ctgatttgac taagctaatg
    19501 ccaaaatacg ccaagaaaac ctataagaac ctagatccgg cctacattaa aggaaatacc
    19561 attgacggta agctttatgc ctttccagta gatgctaacg tctatgctca gcaaatgctg
    19621 tctttcaaca aagaattggt agacaaatat ggccttgaca tttcaaacat caattcctat
    19681 gcagatgctg aaaaggtctt gaaacaattc cacgaaaaag aacctaatac tgctgccttt
    19741 gcgattggtc aagtctttag catgtcaggt gactacgatt acccattgac caaaaatcaa
    19801 ccatttgctg ttaaaatcga tgaaggcaaa ccaaccatca ttaatcagta cgaagatgag
    19861 ccctttaaag caaacctacg cttgatgcat aaatggtata aggaaggctt gattccaaca
    19921 gatgcagcaa ccaacacaga aggctacccg cttgaaggca atacctggtt catgcgtgaa
    19981 gaaacccaag gtcctatgga ctatggcgat accatcttga ccaatgctgc tggtaaagac
    20041 attgtgtcac gaccattgac aaagcctctt aaaacgacct cacaagccca aatggctaac
    20101 tttgtcgtgt caaatgtgtc taaaaataaa gaaaaggccg ttgaagttct ttcccttctt
    20161 aacagcgacc cagaattgct aaatggtctt gtttatggtg ttgaaggcaa ggcctgggaa
    20221 aaggttggcg acaagaaaat caagctgctt gatggctacc aacccaaaat gcacatgggt
    20281 gcttggaaca ctggtaacaa caagatcctc tacacccaag aatcgatcac agatgatatg
    20341 attgcaaagc gtgaccaatc aatcaaagac gctaaagagt ctccgatcct aggctttacg
    20401 gtagatacca aggcaatcaa aacggagcta tcaaaaatct caaacgtgat gaaccgttat
    20461 aaagctagta tcaatactgg tacagtagac cctgatgaag ctcttccaaa acttctttca
    20521 gaccttaagg acgctggttg ggacaaggtt caaaaggaag tgcaaaagca attggacgac
    20581 tttgttacaa aaaataaata aggcaatgga ctttccttgc aaggtggtaa gaactgggga
    20641 cagcctcagt tctttttagc tcaagcaggc atacaagagc tgacagataa ggcctctctt
    20701 agaaaaaagc cagagcctgc ttgcaaggca gttggtccac caaagccctt gctgacaagg
    20761 ttttaccagc cttagtcggc tgtcctcttt ttattaagct tttgtcacaa ttagagtaaa
    20821 atatgctata ttagaagtat ctcatcttat catcatgaca gctaagacct tagtcatctg
    20881 gctgagggat cgttgcttct cttagggcgc tattggtcct acaaaggata ctagaaaagg
    20941 ataatcttat gacaggaatt gaaaaagcct gctttctcat ctggaaaatg atgcagctaa
    21001 cccttatatt tcatttgctt tccttatgtg gtgctgtgat ttttggagtg gggccagctt
    21061 ggcagaccat tgttaccttg tttttggaga ccagtcagca ggagaaacat tattcgctca
    21121 agcgggcctt tcagatatgg cgtcgggtct tcaaagaggc caatctcagc tttttcttct
    21181 ttggattatt gctattattg ctgaatacga gcctgtactt ggccattcaa tttcaatcgc
    21241 tgctgtggtt tagcctatcc tttattatca tgtttgtcat ggtttggctg gtgatgattg
    21301 tgatttacat gaccttttat gcagtgacct atgaaattgc tttttgggag aatctcaagc
    21361 tgtcttttat cagtattttc ttgaatgcca ggcagttttt gttgaccctt gtggttttag
    21421 ctggagttgc ttggtttact tggcagtata agggcttgta tctttttctg agctttggtg
    21481 cgctggtttt gttgctggat atggtcacca agcctaatcg tcgcatggta gatggagtca
    21541 ttgatgacaa gtaaatcttt aaagcggttc ttgatggagc atattaagca gggcttttta
    21601 attaaccgct tgatgaaaat atatagcctg tttatcgtgg ctctctttag cttaagtgcg
    21661 gttggtctaa gcacctattc gattcgaaat acctaccaaa tggttgacaa tcaaatgcaa
    21721 atgcggctag atgagaccct agcaaggcta caatctcaaa actatattac cctgcgcgtg
    21781 ctggagcagc tgatcgggcg tccagaggat tatcgaaatc tgtatcagta catgatattg
    21841 acccctaatc aatatcttac taaggttttt gaggattggg gtgagggcaa aaacacacct
    21901 ctgttttcag agcaggtcag aaggcttttt gatttgtatc cagatttaga tgggctgacc
    21961 ctgatgctgg acgatagcac gtcctatttg tatgcagata ggtcgattaa gaccggccgg
    22021 ctcttatttg gtaagcctca gacgctaaag ggcaattact tagtaaggtc cattcgccac
    22081 cctgagtcag gtgatgttac aggccgcctc tatctgcact ttgcaagccc cagcacgatg
    22141 ctacagcctg agcagcataa gtatctagcg acctttgcct ttgattacta tggcagagag
    22201 ctctttcatc agggaggcgc tgcctttccg gagcttgaag caggtcttaa aaaggcgcta
    22261 aaggcggatc aggctattga tttgacagct ctcagcaaga gctatcatat tcagtacaat
    22321 cgctcgggag acttgctggc ctatgtggcg gtcaaaaggt cttattttat ggaagaggct
    22381 gtgcgtacaa tgctcctgta tggccttggc tcgttattgc tagcttggtt attgctacag
    22441 ctccttttca gggtatttcg caattatatc cgacaggtct ctgagattac agatactatt
    22501 gaaatggttg cagctggtga tttgtcgtta aggattgaca acagtcatat ggaattagag
    22561 ctgtatcaca tttctgaggc gatcaatcaa atgcttggca acatcaatgc ctacatttta
    22621 gaaatctatg tccttgaggt tgagcaaaga gatgcccaga tgcgtgcctt gtcatcacaa
    22681 atcaatcctc attttttgta taacacccta gaatatattc gcatgtatgc gcttagctgt
    22741 cagcaggagg aattggcaga tgtgatttat gcctttgccg ctttacttcg aaataacatc
    22801 agccaggata aggtaaccac tctaaaagaa gagctggctt tttgtgaaaa gtacatctat
    22861 ctgtatcaaa tgcgctatcc agatagcttt gcctaccatg tcaagcttga tcctgtcgtg
    22921 gctgatgtgg aaattcctaa gtttatcatt cagcccttgg tggaaaatta ttttgtgcat
    22981 gggattgatt acagccgcta tgataacgcc cttagcatca aggcgctaga tgaggaggac
    23041 agtattttga ttcaggtgct tgataatggc aagggtatta gccctgagcg cttagtggct
    23101 attgaaaagg gcttagagga gccgcaatcg acggggaata gctctattgg gctgcaaaat
    23161 gtctatatgc gcctatttca caaatatcga gacagagtga cttggtccat gtctcaggca
    23221 ccgactggtg gctttaggat tcagatcaga attagaaagg aagcttaatg tacaaggtct
    23281 tattagttga tgacgaatac atgattttac agggcctaaa ggtgattatt gactggcagg
    23341 cgcttggctt tgaggttgtg gcaacggcaa ggtcagccaa agaagcctta gcttacctag
    23401 atgactgcgc tgtagatgtc atgatttcag atgtcaatat gcctggtatg acaggcctgg
    23461 aattgattga ggcagcaaga gatgtattgc cgcatttgca gaccttgatt ttatcaggct
    23521 atcaggaatt ttcctatgtg caaagggcta tggagctaga gactaagggc tacctcctaa
    23581 agccagttga taaaaaagag ctggtagcta aaatgctcta ttttaaggaa tggcttgatg
    23641 agcagagggc agcttctttg cgtcaggctg cttatcgtga gggcttgata aatctctggc
    23701 ttgctgatga attgagtgag aaagagtttt ttcaactaac gcaggagcaa cccgaggctg
    23761 agcttttagg ctttacggtg ttgtatgtgg attgcaagac ttttagccct gccttagaag
    23821 ccttttttga ggcctccaag cagccctttt acttaaaaaa ggcagagcaa aagaaggtct
    23881 atctagtcat tctattagga cagagccatc aggctaagcg ctttactaat acgcttcagg
    23941 agcgatttta caataccatc aatcagatca ttctaggaga aacggttgtt gattgggaaa
    24001 atgtgtatga aagctataat caggtcagaa ggagcttttt ttacaacagc gaggtgtctc
    24061 aggtagctgc taagaccaac gctaaaattg agctgccgga atcgcgattg cagttttttt
    24121 cctttaacaa gaccttgatg attggggacg agccaactat tgtctccaaa ttacaggcaa
    24181 tctttgagga gatgacagag ctaagcttct ctcctgagga cgtcaagcac gtctcttttc
    24241 tcttattttc agacatttat cgccaatttc cgattttaga tcgaacgacc tacctatcga
    24301 tggtcaagac tattcacgat agtcagtcca ttgatcagat cttatcagcc ttaaaaaagg
    24361 tgcttgagct gacaagcaaa agcaatcagc cccaaaagcg ctattctgat ctggtcagtg
    24421 aagccattac ctgtattcag gaggaatact ctcaggaatt aaccctcaag gctgtgtcag
    24481 atcgcttgca tatcaatggg gtttatttgg gacaacgctt taaaaatgaa acagagtgta
    24541 gtttttccca atacctcaat caggtgagga tccaaaaggc acagcaattg ctgctttaca
    24601 ccaataaatc gattaacgaa attgcctatg agacaggcta taatactaac cattatttca
    24661 taaaaatgtt caaaaaatta aatggtttat cgcccaagga gtttagagac cgttataaag
    24721 ataattatca agctataaaa ggaagctatt aagaaagggg gcgctatgtc tgtagagaca
    24781 atcactggtt caacggatca atctcatggg gatatctatc agcttcactg gattgataaa
    24841 gtagggcgct gccatgcctt ttcaaagggg tggcgctttc tgatggctga tttgcagctc
    24901 gctcaggagc cattttttga tgattcggac tggcagcaga tagctttacc acatgatttt
    24961 agcattaatc agccctatac ggttaatggc gaagctcaaa gtgcctataa gctaggtggt
    25021 gtaggctggt accggaagta ttttgccctt gatccaaagc tggctgacca taaggtctat
    25081 gtgacctttg atggggctta tatggaaacg caggtatacc ttaatgggca tttgatagga
    25141 gagcatgtca atggctatca ggcctttagc tatgatctct cagcctttgt aatccctggg
    25201 caagagaatc tattagcggt tcgggttgaa catctggtgc ctagctcgcg ttggtattct
    25261 ggaagtgggc tttatcggga ggcttttttg accgttcttc cgaaggttca tcttgataag
    25321 gatcggcttc gtttatcctt atcccaggca gcgcttgagg ctgatagcca agcgcttgag
    25381 atagagcttg gactcagcca acaggtcccc ttgagtggct atcagcttag ccttagtctg
    25441 tttgagcagc tggcagatat ccagcagaga cagacagtat atgagagtaa accggtagcc
    25501 ttggacctct tggaggagtc aggtaggctg gtgatgacca ttcctcttag gcatatcaaa
    25561 ctgtggtcgc cagctcagcc ccagctctat cagcttgata tgcttcttta ccataaggga
    25621 gcagtgcttg atcggctgac acttgaaaca ggctttcgac agctgcattt tgatgctgag
    25681 tgtggtttct ttttgaatgg caaagccttt aagctgcaag gggtctgtct tcatcatgat
    25741 cagggtagcc tgggggcatg tgcttatgag gaagctatag ctaggcagct tgttttgcta
    25801 aaggaaatgg gagcaaatac ggttcgtgtc acgcacaacc ctagtgccag aaggcttaag
    25861 gatctggcta acaggcttgg gttatttctc attgaggaag cctttgatac ctggacttat
    25921 gctaaaaacg gtaatagcca tgatttttca agccattttc acaagacagt gggacaccaa
    25981 aatgcagcca ggctaaaggg agtcactaca gcagaaacca cctgggcgca atatagcata
    26041 caggccatgg ttctctcagg tcttcatgat ccatctgtct tgatgtggtc aatcggcaat
    26101 gaattgttag aaggcttctc agctgatgtg agccactacc cttatgttgc taaggagcta
    26161 tgccagtgga tcactgagct ggatcagtca agacctatta cccttgggga taataagctc
    26221 aaggacaagc attttcattg ggcgcaggaa acaaaagcgt tggcagagca ggtcaatcag
    26281 ctccagtccg tgcaaggagt gattggactt aactatgcta aggccagaga ttatgatcga
    26341 ttgcataggg acaacccgac ttggctgctt tatggctcag agacagcctc tgctattaat
    26401 agtagagggg tctatcatct caagggagga gctagtcagg atcatgagct aacctcctat
    26461 gaccagtcaa cggttgactg gggatcctta gctagtgagg cttggtatga tacaatcaca
    26521 agggattttg ttgcaggtga gtgtgtttgg acgggctttg attatctagg ggagcctact
    26581 ccttggaaca agattgactc aggcgcagct gatcagtggc cgtcgcccaa gcaatcctac
    26641 tttggtattt tagatactgc tggatttgct aaggatagct attatttcta ccaaagccaa
    26701 tggtcaaaag acaaaacgac acttcatatc ctgcccagct ggcaggaaaa agaccttcag
    26761 ctagatgatc agggcatggt ggaggttgtg gtttatagta atgctgctag tgtgagaata
    26821 ctttttgatg atggtcatgg gggccagatt gattatggca tcaagaccct gacaaggcat
    26881 gaaacaccag caggccattg ctaccagcta tatgagggtg acgatgcagc agaattacct
    26941 catcaaaacc tttacctgac atggaagctt ccttatcgct caggcagctt gagagctatt
    27001 gcttatgacg acaagggaca ggtgctcaca cagaccagcg gtcgttcctg tgtgagcagc
    27061 taccagcagc ctgctcagct ttcctggtcc tgctttgagc ctcctaaact gcttgcagag
    27121 cctgcgctac tttatcttga attgtctttg ttagatgcta atgagacctt ggtgctcagt
    27181 gctaatcctg tgattaagct tgaggttgag ggtcctggag cctgccttgc tctggataat
    27241 ggcgatcctc gtgaccatag gccctatact gccttgtcac gccgagcata tggtggcaag
    27301 ctattagcca ttattgctct tgatggtcgt gcgggtcagc ttagaataac agctagagcc
    27361 gcaggattcg tggaagccag ctatcagttg acggtttctg aagcagccgt taatgagaag
    27421 cttttagcct atcagcttga taaatacagc tttatcacta atgagacaaa taagcctagc
    27481 aagccctatg caaggtcaag aggatcagct gttgatagct taatgcctaa tcctgatagc
    27541 tgcttaaagc ggcaaggcca ttatctgcct gataattctg taatggtttt tagctataca
    27601 acagcattat caaggccact gacctttcag ccactgatca aaaggctgct aaagggcaat
    27661 gatatcattc taccagactg gctgcagcct agggcagctg ctggccagtt atttaccaag
    27721 gcttttccta ttgattggca gctaacagag gcagtttttt ctgaggagtc aagggttagt
    27781 gggcagaccc tttgttttgg agaggctttg gagcttgaag ctatccttaa gtcagataca
    27841 aaaggattaa ggatcaatca agagcttagc ttagttgcta aaaagaagcg gctgtttcag
    27901 agtgataccc agcttagcta ccgctatcaa tacgatacca tacaggccat tggtgccatt
    27961 agcctgacag gactaaagaa gcccttaagc tcgcttaggc ttgttttgga ctatcgcagc
    28021 agcaccaatg cgccatcaaa acagctgatc ctatcgcttg atcagataga acagccctgt
    28081 cactacatca tgctggaaga agtagttgat gtgctaagcc tggacctaac attagagcag
    28141 ccgatcagac aggcttttga cttagctagg cttcagctag gcctttggag catggttgag
    28201 gaggcttagg cttcaagctt atcggctcat actgtcaata ggattgagct gagacagtct
    28261 ttgaaaaata aggtataatg acagtaaatg cctagcaagc tttgctaggt tagcaaaaaa
    28321 taagcatcgc ctgatatgat gtaaaggagg aggtatttga tgctagagcg tttatcaggt
    28381 cagacacgat taacagcttt gctggcagca ccggcacgtc acagcctatc accgaaaatg
    28441 cacaatgcag cttatgctaa gctggggctg gattatgcct acctagcctt tgaggttggt
    28501 aatgctgagc tagctgctgc tgttcagggc atgcgtgcct tgggtatttg cggtgcaaat
    28561 gtgtccatgc caaataagca ggccattgtc ccattgcttg atgagctatc accggctgca
    28621 gccttagctg gagctgttaa tacggttgtt aataaagatg gcagaggtca tcttgttggt
    28681 catatcaccg atggcacagg tgctattcga gccttagcag aagaaggggt ctcgataaag
    28741 gatcagatca ttacgattgc cggtgcaggc ggtgcaggca cagccattgc tgttcaactg
    28801 ggacttgatg gcgccaagga gattcgacta tttaatcgga aaacagctac ctttaagcag
    28861 gccaagcagc tggttgctag aattaatacc caaacctcag ccctggcaag ccttcaggat
    28921 ttagcggatg atcgagcctt taggcggtct atttcagagt ctagcattta tattgacgcg
    28981 actggtgtag gcatgaagcc ttttgaggag catcgcctga ttactgatcc agctcttatt
    29041 cgcccagatc ttgtggtttt tgaccttgtt tatcacccgg cagaaacaaa gctcttagcc
    29101 tttgcgcgtg agcatggggc taaaaaagtg atgaatggcc taggcatgct cctttaccaa
    29161 ggagcagaag cctttaagct gatgacaggt gaagacatgc cggtagccta tatccgagag
    29221 cttttatgtc agaacaagga atgaacgcct gctgctcacg ccggtatagg aaaaagaaaa
    29281 aaaggttaat tgctcagctc tttgattggt cttgaggttt gtcggcattt tatttataat
    29341 aaaaagcacc aaaagcaaag gagcagccta tgatattgac acaatttgac cctgactacc
    29401 aagctatcat taaccctaag gaccttgtag cagaaataga tgactttcct aaaacagtag
    29461 tcacctgctt tgcaagagca acctttaata gggtacttaa tgcactgcca catcgactga
    29521 tagccacaac aagcgttgct aatcttgata ttccaatata cgaattagat gttaaagggc
    29581 ataagcttgg ctttttcaat tcctacgttg gagcagctgg ctgcgttggg gttttagagg
    29641 atatcattgc tatgggaatg aagcagctct tggtttttgg gacctgtgga gtcttagacg
    29701 ctactatcag tgaaaactct attattattc caactagtgc tattcgagac gaagggacca
    29761 gctaccacta tcagcctgct agtcatgaca ttgcagtgaa tcaagcttat ttaacaaggg
    29821 ctattgatgt tttagaacag cattcccaga cctataccct tggtaagacc tggacaacag
    29881 atggcattta tagagaaacc agagacaaga tgattcaacg aaagcaggaa ggggctattt
    29941 gtgttgacat ggaatgctct gcgattgctg ccctagcagc tttcagacag ctagagcatt
    30001 ttcagttttt ttattccgct gataatctag atgctgatga atgggacgca agaagcttag
    30061 ccaatgaagc agacctagaa gccaaggata acattgcctt tattgcctta gagttggcct
    30121 tacgattatt taaggataat taaaaaagca ccaagagcta tgaagtgcct ccaaaaggtt
    30181 agattaaggc tctaacgcct gggagatcag ttcagctcaa ggtgcttttt aggtgtcatg
    30241 cagacagctc acctctgcat gtcaatataa tgtttagagt agcctatgct tcttatacct
    30301 atgccttagc attcacctag ggacaaagca atgaagctta ggcctttcac cttactgtga
    30361 aaaaagtggt cttttctcat caaaagactc agtaaacaag aggctttgaa gcctttttgt
    30421 ttttcagaag cagcagtttt ttcactcgac taataagaca ggagaaaagc cttctcaggc
    30481 gatatctagc aggcttctta gccaatccag caggcgactg tcatgcttag caataggaaa
    30541 gcttacatag ccttttgtcg ttggcaaaat gaggacaata tgctgaccag aatttttctt
    30601 atctgttttt aaaacagtca tcaaggcttc ggctgtcatt gacttagcct caagtgtggt
    30661 aggtagctga taagcctcaa aggcagcctg taatgcctct aaatcctgtt ggctcaatag
    30721 ctgctgctgg acggccagct tggcctcaaa gaccatgcca atcgcaatag cctcaccatg
    30781 cctgtaaagc tcgtgatggc ataaggcttc aatcgcatgc cctagcgtat gcccgaaatt
    30841 taaggacatg cggagattgc cttcaaattc atccttttca accactcttt ttttatggca
    30901 aatcgcttga aaaatcattt gcctgagctg ctcttgattg cggtccttgg ggaaggctag
    30961 gagctgttga aagagcttgc gatcatgaat aaaaccaatt ttaatcattt cgctgatgcc
    31021 gcaggcaaat tctctttcag aaagcgtgtc taaaaacttg gctgacacga taatctggtt
    31081 tggagggtag atactgccta tcatattggt caagccctta aagtgaaccc caaccttacc
    31141 accaatgctg ctgtctacct gactaagtaa ggttgttgga atctgaacgt aggaaatccc
    31201 gcggtaaaag gttgccgcaa caaatccccc aagatctcca atcacccctc ctccaacagt
    31261 aacaatgacg tcctttttag aaaaattagc cctaatcagt cgatcgtaaa tccgactaac
    31321 ctcctctaga gacttagatt gcccccctgg agcagcaata tgaaggtaac tatcgtaatc
    31381 ctgttgaaaa cgtctaaata aaggctggta taaatcaaat accgtttgat cagtgataaa
    31441 taatagcttg acgtctcctt tttcagcaag aaattgattc agcggctgaa aaatatcgtc
    31501 tgtaaagata atcggatagt cattgatacg agacttaacc tgaagtgttt gtgtcatgcg
    31561 tctttctctc ctaagcacca ttagttcaaa tgactggacc tgtggctgct gttagttagc
    31621 tttcccaaag ctcttttcca agctgctcta gctgttgata atcaatctgc tgcgcggcat
    31681 ctgacaaggc aagatcaggt gtagggtgca cctccatcat aataccattg gcaccgatag
    31741 ccttagcggc cttagccgca ggcaatagta aatctcttct tcctgttgag tgagagacat
    31801 caacaatgat tggcagcttc accttttgct gaataatagg gactgccatg atgtctagca
    31861 tatttctagt ttccacatca tagccacgaa ccccacgctc gcataaaata atattttgct
    31921 tgccattttc ttgtaaataa gataaagcac ccaaatattc ctcaatggtt gccattagtc
    31981 ctcgtttaaa caagataggc ttgtcaatct ttgacaatac ctttaacagt tcaaaatttt
    32041 gcatatttcg agcgccaatc tgaataatat ctaaatagtc ataggcttcc tctagctgcc
    32101 tttcagacat aatctcacta acagccttca gcgaaaattc ctggcaaacc tcatgtagat
    32161 aggtaacccc tgtcagccct aagccctgaa aggagttaga agaggttcta ggcttatagg
    32221 ctccccctcg aaaatacctg tagcctaaag ccttggcact tgctgctgcc tgtctgattt
    32281 gctgataaga ttcaatggca cagggaccaa caataaagtt actcttttga cagcccttgt
    32341 ttaaaaaatc agctattata tcgtttccca tttatactct ttcctaatat gatattgaga
    32401 gaatgattcc ccaaaggtaa gatgacagct ctgtcttaga taatactgtg aataaggcat
    32461 gacagaacta ttcatagctt gggaaatcat accataatca agcttaaatt tcaagctaat
    32521 aaagagagtg accagctcgt tgacaaagga gaagcttttg agaatcctag ccctctaagg
    32581 tagagatttt atggctatta gagctgttga gaatgcttat tagctggaat aggcaagcat
    32641 ggtggggaag tgctgatgat tgagtatcat gatgaggcta gttatagctt ttattgtggg
    32701 agagtttagc ttttcaaata caaaaagaaa aggtttacct atatcgtttt tttggtgtat
    32761 atataatata tagaaagcaa actattttag aaacagaggt aatggtagat gttaaggtat
    32821 ttaaaagcga ttttatatct attggctccc agattagctt tttcagtaac aggtgtatta
    32881 tttcctgatg tttttgataa tttattcttg gtttataata ttttaatgac acttgctttt
    32941 tggcttgcga tttattctgt tgacctccca gaaaaatagt tgcgggactt gtttagtagt
    33001 tggttaacaa agggtagatg atcagttaaa ggtgaagcgt ctgagctatg ttggccatta
    33061 tgcgtacagc tggcaaaatg cttttgatcc aatcggttaa acctcaagct attctctttg
    33121 ggataacaaa taccccatct gtctcagaca aagaatggca acgcctaaat aggattaaca
    33181 tctgcaagtg ctcttgggac tgccaatgct cttagtagca taggtgattt ttcagcgcta
    33241 gagacttttc agcagatgag aaatagtcgc aataaacgaa gacaaaaaga cttggcttga
    33301 gctcgtattt ggccttaaaa tagtagtcag tcgagcttaa aaaaaagtca ttgcagctta
    33361 tgaaggttat cgtatcctta tttcaactga gctaggtaag ctagggagtt tcctttaggt
    33421 gtaacgatag aagcgatcaa ataattactt catttaaaga taaggattgt aataagcata
    33481 gaaaagagca gttacttgac ataactactc aatgtaaaac cgtttcaggc ggtggctttt
    33541 gttattagat aaaaaataat cgtcatcatt cggccaaagt tagaacggtt atgttttatg
    33601 ctcatctttg aagatgttat agcacaagcc aatagggaga ctaaagctta aaaagagttt
    33661 gagtagcttc aaaggctgct agctttttgg cctcctccat tttgttagct gttgatgaat
    33721 cgcccatagg caccaccacc cactcagaac gagcagccac ctgtcttaat ttttttactc
    33781 taccactgta gcatgccaca agaaaaaatc agaacactaa tgacatttaa aaaaaaaaaa
    33841 aaaagacttg cacaccaaaa caagttatag tatcatagaa aggtagccgc tatagttaaa
    33901 tggtataata aagcaatggt aatgcttcgt tccgagttcg attctcggtg gtggcatctg
    33961 agtactgtcc taagtcttat taggacggtt tttttattgc taggtgaacc aatagtagtc
    34021 atctgtgaat cattaccata gtggcttctg ttcgcccaag catagcaaag ctgctgtcag
    34081 aatgaaccca gccaacaatg tcaatagaag cagcaccaga caagccttta gtcacccatg
    34141 ctttaaagat tttacggctg taatgttagt aactgttacc tgttttgttc aagttgtctg
    34201 tgacatcaaa tcacttgatg ctaccagtac tgtcaataca ttagctgtca cttggcagtt
    34261 gttctgacta ctactaaaaa tagcagctat cagcgttgca atcaaaaaag aatgcgaatc
    34321 aagctctcct gatcagctta actttttgaa agagtttgta cgggtcaagc atcagcaagt
    34381 cagactgcct tatttgtttt tatcataagc ttctaagaaa atagcacaat aagccaggct
    34441 gtggtataat ggtaaggatt aagtcagaaa gaggggggca gacatgtctt atgagcaaga
    34501 ctttttgaga gattttgaag actgggtgaa ggctcaaatt caggtcaacc agctagctat
    34561 ggcaacgagc cggcaaattg caaaggaaga taatgatcaa agagccagag atgcctttat
    34621 tcgttatgag agtaagctag atgcttatga gtttttatta ggaaaatttg ataattataa
    34681 taaaggtaaa gcttttcatg aggtgccaga cagcctattt ggtagccgtc attattagag
    34741 gaagggataa gcagtaatca tggcaagacg atacaatcgt aaaaaacaat acaagctaca
    34801 gcttaagcgt caaggactgc tcaaggcagt aatcaatcaa gtggagcaga ctgtggaaaa
    34861 ggtggttgat aagactaaag aagcagtgca taccgcttca caaatggtaa cagcatcaaa
    34921 gacagagact gctgatctac aggataagca gagcattgct gaaaaagcag ctcagcctaa
    34981 agcagatgta gcttctagta gcttggctga cagttctgag gtttcaagtg aaaaagaggc
    35041 ctcaaaggct agcagtgaag tcttatcacg cgatgctttt gcagagttgg ctgaggtttc
    35101 agagcttcgg gcagatattg ttacggtgct ttttgaggct ggtattaggt cagctgctgc
    35161 ttttagccaa tggacagagg cagagctttt ggcgcttaag ggaattggac cagcgactat
    35221 cagcaagcta aaggaaaatg gtgtcaactt taaaaagtag tctgattttt attgcttaat
    35281 aagtataaat ttgttagaat gttagcaatc agaggtatct tgagtttgtc tgttacagag
    35341 agcggtggtg ttgagaaatc cgcacagatg tcaagttatg tagctgaggc ttacaatgga
    35401 aaaatgataa agcagcagat taagtgtaat ctgaaacagt ggtggtaccg cggattatta
    35461 gtgaattcgt ccctgtctag tcgattgact aggcggggtt attttttgga ggacttgcta
    35521 tgattgagat aatgggttct gttgagaata atagattacc agatgtcaaa actagtcgtt
    35581 tgctgctgcg gcagcgtact ttagctgatg ttgaagcgat ttttgcttat gctagccgac
    35641 ctgaggttag ttacccagca ggctttccac ctgtgaaaac ccttgaagaa gaggagcatt
    35701 acatcgcaaa cacgatgcct aagcgctggc ttttgcaaca gctgccggca ggctatggca
    35761 ttgccctaaa gggtgacaat aggattattg ggtctgttga ttttaacaac cgtcacgcag
    35821 atgatgtctt tgaaatgggc tatctgctcc accctgatta ttggcatcag gggattatga
    35881 ctgaggcagc gagtgccctg ctagaggttg cctttactct gcttaagctt cataaggttg
    35941 aaatcagctg ttacgattac aatatgggga gtcgtcggat cgcagaaaag ctagacttca
    36001 ctcttgaggc gaccattcgt gatcgcaagg acgctaaagg caatcgctgc gcagacttgc
    36061 gctatggact gttgaaaaga gaatgggaga ggcagtgtag ataaggagta gactctctaa
    36121 aatatgcgtt aatctgtcaa aagcatttca taagaagtcc tcaaactcaa agcgcttatg
    36181 actaccaaaa ctggttagcg cttcgccaac cagtgtcatc agtttctggt agtctgcctt
    36241 gagcagcaag tgttatgtta agtgaggtga gaagaggtaa gagagatcgg aaagaggttt
    36301 ggtatgaata ttatcttaat tggagcacag gcgtctggta agatgacaat tggacaggaa
    36361 ttagaaaaac tgactgacct gactttattt cataatcatg aatcgattga ttttgtgact
    36421 aagtttatac caatgtcatc ggaagctaga gaactaattg atgagctacg attgctattt
    36481 tttaaaacat ttgcaaaacg tcagcaatca attattttta ctgttgtcat tgattttaat
    36541 gcacctgaag atatagcgtt tttggaaaca ctacagagtg tgtttcatga tttcgacaga
    36601 gaggttttat tcgttgaatt agaaatagat ttaaaagaac gcttaaggcg aaataaaact
    36661 gaaaatcgac tttaccacaa accgataaag cgtcatttgg agtggtctga gaaagatatt
    36721 ttggatactg ctaaatttgc taactttaac cctgcaaagg taccagaaaa tcttaaatat
    36781 tattgtaaaa tcaataatac gagtctttct gctcaagaaa cagcgcagtt tatcgtccaa
    36841 aaaatgaaag agttagaagt aagctagaaa ggacaccata tgtcaaaaga actttcaccc
    36901 aaatacaatc cagctgaggt tgaggctggg cgttatcaag cttggctgga ccaagatgtt
    36961 ttcaagccat caggcgacaa gaaggctaag ccgtatgcta tcgtgattcc accgccaaac
    37021 gttacaggga agctgcacct tggtcatgct tgggacacga cccttcaaga tattattatt
    37081 cgtcaaaagc gcatgcaggg ctttgatact ctctggttgc ctggtatgga tcatgcaggt
    37141 atcgccactc aggctaaggt cgaggagcgc ttgcgcgagc aggggatttc ccgttacgat
    37201 ctcggtcgtg acaagttctt agacaaggtt tgggaatgga aggacgagta tgcagcaacc
    37261 atcaaggagc agtggggtaa gcttgggctt tcactagact atgcgcgaga tcgcttcact
    37321 cttgatgagg ggctctcaaa ggctgttcgc aaggtttttg ttgagcttta caagaaaggc
    37381 tggatttacc gcggtgagtt catcatcaac tgggactcgg cagctaggac agctctttca
    37441 gatatcgagg ttatccataa ggacgttgag ggtgccttct accacatgaa ctatatgcta
    37501 gaagatggtt cgcgcgccct tcaagtagca accacacgtc ctgaaaccat gtttggagat
    37561 gtggctgtcg ctgtcaatcc agaagatcct cgttacaagg acttgattgg tcaacatgtt
    37621 gttctgccaa tcgtgaataa gctgatccca atcgttggag acgagcatgc ggatccggca
    37681 ttcggaacag gggttgttaa aatcacacca gcccatgacc cgaacgactt tgaggttggt
    37741 gggcgtcata atctcccaca ggttaatgtc atgaatgatg atggtaccat gaatgagctt
    37801 gcaggtgaat ttgcaggtat ggatcgattt gaagctcgta aggctgttgt ggctaagcta
    37861 gaagaaatcg gtgcccttgt tgagattgaa aagcgtgttc attcagtagg tcattcagag
    37921 cgtacaggtg ttgtggttga gcctcgcttg tcaacacagt ggttcgtgaa gatggaccaa
    37981 ttggctaaaa atgctattgc caaccaagac acagatgaca aggttgactt ctacccacca
    38041 cgcttcaacg ataccttctt gcaatggatg gaaaatgtcc acgactgggt aatctctcgt
    38101 cagctttggt ggggacatca gatccctgca tggtacaacg aagcaggtga catgtatgtt
    38161 ggtgaggaag cgccagcagg tgatggctgg aagcaggacg aggatgtcct tgacacctgg
    38221 ttcagctctg cgctttggcc attttcaact atgggctggc ctgatgtaga ctcagaagat
    38281 ttccaacgtt acttcccaac gtcaacattg gtaacaggtt acgacatcat cttcttctgg
    38341 gtgtctcgta tgattttcca atcgcttgaa tttactgggc gtaagccttt ctctaacgtt
    38401 cttattcatg gtctgattcg tgacgaagag ggacgcaaga tgtctaagtc gcttggaaat
    38461 ggcattgatc caatggacgt tatcgaaaaa tatggtgcag atagcctacg ctggttccta
    38521 tcaaatggct cagcccctgg tcaggacgtg cgcttctcct atgaaaaaat ggatgcgtcc
    38581 tggaatttca ttaacaagat ttggaacatt tcacgttaca ttctcatgaa taatgagggc
    38641 ttgacacttg agcaagcaag tgcaaatgtt gagcaagttg cgtctggcgc tgctggaaac
    38701 gtgacagact gttggatcct ccacaatctc aatgaaacaa tcggtaaggt cacagagaac
    38761 tttgataagt ttgagttcgg tgtggcaggt catatcctct acaattttat ctgggaagaa
    38821 tttgccaact ggtatgtgga gctgaccaag gaggttctgt acagcgacaa cgaagacgag
    38881 aaggttatca ctcgctctgt tctcctctac acgctggata aaatcctgcg tctccttcac
    38941 ccaatcatgc cgtttgtgac ggaagaaatc tttggtcaat acgctgaagg ttctatcgtg
    39001 acagcggact atccaacggt tgatcctgct tttgaaaatg aagctgcgca caaaggcgtg
    39061 gaaagtttga aggacttgat tcgtacggtg cgaaatgcgc gtgcggaggt taatgtagca
    39121 ccaagtaaac caatcactat ccttgtcaaa acaagcgata gcgacctgga agccttcttc
    39181 aacagcaatg tcaactacat caaacgcttc acaaatccag agaggcttaa gattgcttca
    39241 agcattgtga ctcctgagtt ggccatgtcg gctgttatta caggtgcaga aatcttcctt
    39301 cccctagctg atctgctcaa tgtcacagaa gaattagctc gccttgaaaa agaattagct
    39361 aagtggcaaa aagagcttga cctggtcagt aaaaagctca gcaatgaacg cttcgttgct
    39421 aatgccaagc cagaagtcgt tcaaaaagaa cgcgacaaac aggctgatta ccaagctaaa
    39481 tacgatgcaa ccgtagagcg catcaaggaa atggagaagt tagtaaggta ggatagtgat
    39541 catctaagag ccaattggct ctttttttga tatactgtca aggagtaatc atcacaatta
    39601 tctatataag tcaaaggagt gtctcatgaa aaaaagagtc attggttggt taggtgtgct
    39661 ggtaataggg cttatgcttg gtctgatatg gtggaaatgg ttagtggcag atcggccact
    39721 aacccaagca ggtcaaggaa gtcatgacca cagcagcgac aaaggcctca gtgccgcata
    39781 aggaaaaaat ggaatcaaaa gagcctgaga catcacatca gccagaagcc tatcctgatc
    39841 ttgctagcta tcaggaattg gctgttcatg tgtcgattgc agaccaagtc atgaccatta
    39901 taggagatgg taaggttatt tttaagacca gcgtgtcaac aggagcaaag gaaagtccaa
    39961 caccgacagg gacctttgtc attgagcctg agcgaggaga ctttttcttc aatcaggcat
    40021 cagaagaggg agcttattat tgggtgtcct ttaaggacca tgggatttat ctgtttcaca
    40081 gcctaccaac agaccaatat ggcaatgaga ttccagagga ggcagagaga ctgggacagc
    40141 cagcctcaca tggctgtgtc cgcatgagca gagcagacgc caaatggttt tatgacaata
    40201 tcccagaagg catcagcgtc acaatagaat agccctaatc tccctcagaa tagcctgagc
    40261 agatagagga agagcctgtt aatattagca ggcttttaaa gctccttaaa aggctgcaaa
    40321 aaggaacgaa aaaagacctg aaacaggtcc attgatctaa gagaagacaa gtaactagcc
    40381 ttctagcaaa gtgttttaaa aatgcgttag tttagtagct tcgtgataat acaattaata
    40441 atatttattt aaaaaaactg taaatttcga ccactgttcc tggatttttt catttaaacg
    40501 tttatgccat gacttatgag cattctctct aatttctttt aggtatatat tttctactac
    40561 ccttttttga ctatgttctc gctctttttt tatttgctgt cttaaattct cttgtttttt
    40621 ctgttcttct aactcttttt gagctttctt ctgttcttgc tctattatgt cttgaggttt
    40681 agattctcct acaatccata tttctgaacc taagacaaaa ccatctgagg taatatgaac
    40741 tctaaattta tcaccattag aagcaatttt attatatgga acatatgttt cttctttgga
    40801 atttgttttt tgtgttctcg ctgattctaa agagaacaca atttttccat cccactttgc
    40861 aattggatag taccggttat ttgttaagtc accattgctt tttttttgga cttgtactaa
    40921 ttcagtttcc ttatcatctt cttcgacttt aaatattcta atcaaagatc ctggactagt
    40981 ttttactact atttctttgt cattattttt gattggttta acgccaaagt ctcgagcgtt
    41041 ttcccaatct cttctaaatc ctattacctt ttggtcacca atttgtggtg cttctgtata
    41101 atcatcataa ccataatagc cttgccctaa aactggagaa ttttcataat cactatttgc
    41161 acttacttcg ttgaaacata ttaaacttag taaaggtaaa ttaacgatta aactcatcac
    41221 taacttcttc ttcattttt
//
LOCUS       DARYMD010000015        39312 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYMD010000015 DARYMD010000000
VERSION     DARYMD010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39312
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(115..1254)
                     /locus_tag="TU818_000697"
     CDS             complement(115..1254)
                     /locus_tag="TU818_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL0923536.1"
                     /translation="MWSEKHKSGKVNFVERYKHPYTGKWCRASVLMEKDTPRIRKEAQ
                     KYLDEKISKILTSLTTTDAYLLDVMNEWWEHHQKSLKSTSVRSLDFRIRELRNLIDPE
                     VMIAKITTKYLQSIIDKIPGSYDKRKRARQLLKQTFDYAIALEYVSINPVISTQLAKP
                     VKTIKDFEDVAQKFLEKDELKRLLDEMYRRKGSIKMAYLAEFMSLNGCRIGEALAIQP
                     DNIKNDIIEIHGTLDYTSNGYRNAIKTTPKTNSSWRETLITKREKEIIQDILKINALE
                     KNTNPNYKDMGYIFISRNGVPIQDNALNTSIRAANKRLEKPIQKELTSHIFRHTLVSR
                     LAENKVPLKTIMDRVGHADSKTTQQIYTHVTKSMKNEVVDILNRL"
     gene            complement(1382..1648)
                     /locus_tag="TU818_000698"
     CDS             complement(1382..1648)
                     /locus_tag="TU818_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HEL0923537.1"
                     /translation="MGFLDNVKEASTVSTASGENYEYVVLQVTLKEKLIGTGSGNLTE
                     LENVINKQAKKGYRLHTITTSNGGSKGFGGGDRIQATMVFEKIK"
     gene            complement(1660..2046)
                     /locus_tag="TU818_000699"
     CDS             complement(1660..2046)
                     /locus_tag="TU818_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL0923538.1"
                     /translation="MDLSLQEYVKGHGYELLFYDNRGTDKEAFVNHDCKVLGIGSYLD
                     DHEKKKAIYHEIGHKEHTNRQYELNRELCELEADRNMIHHLLKEELSYLDNVNEFNYA
                     RFMEKYKLKTITDEKMVIDEYYTLIG"
     gene            complement(2049..2399)
                     /locus_tag="TU818_000700"
     CDS             complement(2049..2399)
                     /locus_tag="TU818_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0923539.1"
                     /translation="MFPTFEKIKELCKQRGITLIQLEETLEYSRNTLYKLKTQKPNAE
                     RIAEIADYFNVSTDYLLGRTDNPAIANGTTSQKTIDFKEIAAQSMSYDGKPLTDDDID
                     LIAAVLEQRFKNRD"
     gene            2695..2940
                     /locus_tag="TU818_000701"
     CDS             2695..2940
                     /locus_tag="TU818_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923540.1"
                     /translation="MKKNIVDLQKRKEHFQWVADSLEGKENELYVERDWYDNPTLISK
                     EDAKKEVEQIRQELILLQNKSFIEYILQLLHQLFHRQ"
     gene            complement(2891..3679)
                     /locus_tag="TU818_000702"
     CDS             complement(2891..3679)
                     /locus_tag="TU818_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923541.1"
                     /translation="MSRYSDYKYANTILKSIEERPEKYLIIHYSCESFYNLGGKSPRI
                     ASISVRQFNNAQTNNFSIHQYSEILDTPITDDTYETIEKELLTDFFTFVDRNTDKNWI
                     HWNMRDTVFGFHAIEQRFKVLGGTPIIIDDDKKIDLAYLFKKMYGGGYIDNPHIEKLL
                     ELNNLTPHRFLTGKQEADAFSSRQYHELSMSTSSKVNSFSTFLTLAINDDLKTNTPKW
                     KMRGTNLSGLLSTFQETISGKVIIGIINLIVGGIVGAIIAKYIQ"
     gene            3730..3921
                     /locus_tag="TU818_000703"
     CDS             3730..3921
                     /locus_tag="TU818_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0923542.1"
                     /translation="MPDIAVGREKVVTFLKSNNIKKSDLAAAYGLNRQEVTNILSGST
                     RGPKANQFILRVIADYSIE"
     gene            4002..4313
                     /locus_tag="TU818_000704"
     CDS             4002..4313
                     /locus_tag="TU818_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEL0923543.1"
                     /translation="MPKAELVYRPAKQSEKAEAGDYEHLCQIWEGLTVGTAKVWAAEM
                     RDHPDFKQFINNPTHRIVFIDYEGFRLFVKWKSRNRYKPKKETLAEMLENIKFEKRVG
                     A"
     gene            4315..4485
                     /locus_tag="TU818_000705"
     CDS             4315..4485
                     /locus_tag="TU818_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923544.1"
                     /translation="MNKLELFLLVTTVALAIVARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKKWSAERYV"
     gene            4478..4681
                     /locus_tag="TU818_000706"
     CDS             4478..4681
                     /locus_tag="TU818_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923545.1"
                     /translation="MSKWELQKQLLENATDFESTVEALLDLNESGEISDLELLLNLKD
                     KFRSYSKEKIRILNEILKLGGAE"
     gene            4678..5064
                     /locus_tag="TU818_000707"
     CDS             4678..5064
                     /locus_tag="TU818_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923546.1"
                     /translation="MMTTFEKIIKKINRIEGELVKPEAERRDSLPILSAQLGSIKQDL
                     KLMLWIELLTLNDVERYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDKR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            5208..5411
                     /locus_tag="TU818_000708"
     CDS             5208..5411
                     /locus_tag="TU818_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923547.1"
                     /translation="MNYLEYALVYLERELEIIDNEVIEVELPGGDWEFVPNPYYEKGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            5499..5798
                     /locus_tag="TU818_000709"
     CDS             5499..5798
                     /locus_tag="TU818_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923548.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            5798..6955
                     /locus_tag="TU818_000710"
     CDS             5798..6955
                     /locus_tag="TU818_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEL0923549.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKAFKENSDFYNEEMEEMTELYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGTLEKLIGKTTFADLLAEVIDKPQGKPVLVKNSDKRPALNSLEQAIKDFE"
     gene            6964..7527
                     /locus_tag="TU818_000711"
     CDS             6964..7527
                     /locus_tag="TU818_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEL0923550.1"
                     /translation="MIMTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHVFMS
                     VSSKTKPQIIDKYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            7570..9492
                     /locus_tag="TU818_000712"
                     /pseudo
     CDS             7570..9492
                     /locus_tag="TU818_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
     gene            9497..11881
                     /locus_tag="TU818_000713"
     CDS             9497..11881
                     /locus_tag="TU818_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL0923551.1"
                     /translation="MKQEKLIVKSSPLQELHIATGNSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWRDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTEGS
                     TANGLVIYDEVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDITPTNKLPSSK
                     AMNAFVSDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNSFKTKFDPELHARSSHPVVYDPEAACETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYAIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRKALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLAKNAFNHRLRELSYENKNVKSGGKQAKNWVGFKLKSEF"
     gene            12268..12543
                     /locus_tag="TU818_000714"
     CDS             12268..12543
                     /locus_tag="TU818_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEL0923552.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFASPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDIALKEMENWV"
     gene            12540..13862
                     /locus_tag="TU818_000715"
     CDS             12540..13862
                     /locus_tag="TU818_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL0923553.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWSTEIGKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGARLETSQTRFKDKYFVPDKRNGLIIYSWALRDGAEAEIYNKIE
                     DICISMKAKDYLKLPPRTDNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLAN
                     KLLQMANGAIYDDDKTTVAIHDDKLDALENVVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            13863..14051
                     /locus_tag="TU818_000716"
     CDS             13863..14051
                     /locus_tag="TU818_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923554.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLRFWDSCEAT
                     VKEKYTREREMKNEQTKI"
     gene            14032..14259
                     /locus_tag="TU818_000717"
     CDS             14032..14259
                     /locus_tag="TU818_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923555.1"
                     /translation="MNKQKFEKLDKVKELLDELKMSEFMAPLLVGDQIMEIINDLHND
                     PGQFGAQVFLPSPDKKYKFVVRICREENLED"
     gene            14284..14469
                     /locus_tag="TU818_000718"
     CDS             14284..14469
                     /locus_tag="TU818_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923556.1"
                     /translation="MAENKTGMMTLPIDYANRALAKEEILDELVEREIVDVDLLIELA
                     EDNPFWMSALNFNRGTK"
     gene            14466..14759
                     /locus_tag="TU818_000719"
     CDS             14466..14759
                     /locus_tag="TU818_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923557.1"
                     /translation="MNTNEKVIDTICHIRHCGDRYDMCQDMRSWVAERNGLIQDLLKA
                     KKQIDRNRIAKRLDRAQKNISDIITKVTGDLWQGSDQVIAEQCFLKVLEEMQK"
     gene            14756..15472
                     /locus_tag="TU818_000720"
     CDS             14756..15472
                     /locus_tag="TU818_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL0923558.1"
                     /translation="MNIKEAKIGDKVWVEGIINSSFSNGGVHVNHAGVDAFYDLERTK
                     IKPDGYAGQSPKYLKNIIAKMRELPEHDRAVWIKGIFKEFGIENDISYYLGHKQGVLQ
                     AKDSLKPEVLQYVADWYEKHKDNLEYYIWEYIAEWDNQEKDDFFVFMNFSAFKPIQTL
                     VNMHQFGYTIKKEKLYTVEIPNPNAKQIALRLEKWVEGKVRIVATYSSNNFTDYMRLT
                     EREIRKDFDWAWQFAEEVTG"
     gene            15469..15885
                     /locus_tag="TU818_000721"
     CDS             15469..15885
                     /locus_tag="TU818_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEL0923559.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            15975..16427
                     /locus_tag="TU818_000722"
     CDS             15975..16427
                     /locus_tag="TU818_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL0923560.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            16417..17694
                     /locus_tag="TU818_000723"
     CDS             16417..17694
                     /locus_tag="TU818_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL0923561.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGAEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAN
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLPSFFGLDYGFINDPSALLHV
                     KIDDANKKLYILEEYVRKNLTNDEIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWIVDERCVKTIEELENYTWKKDKKTNEYTNEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            17710..19242
                     /locus_tag="TU818_000724"
     CDS             17710..19242
                     /locus_tag="TU818_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0923562.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEKIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKAYTSDTIYTYEDYN
                     LETKGMRLKDYEGHFFRGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            19202..20650
                     /locus_tag="TU818_000725"
     CDS             19202..20650
                     /locus_tag="TU818_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL0923563.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQKDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKVASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKRLKQGFVRGEHPRAMARDLAKR
                     FNVANHRAETLIRTDGTMVINNATARRYLNAGLKYYRDLVRLDDRTTEICRTIAKENK
                     RKLLSELKPGINVAPYHFNCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     HKPQLSLLNEYVKNGTPYKVDGHSVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HIKTPDYLVDGAPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGG"
     gene            20678..20866
                     /locus_tag="TU818_000726"
     CDS             20678..20866
                     /locus_tag="TU818_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923564.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKEG"
     gene            20871..21128
                     /locus_tag="TU818_000727"
     CDS             20871..21128
                     /locus_tag="TU818_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923565.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRK"
     gene            21305..21874
                     /locus_tag="TU818_000728"
     CDS             21305..21874
                     /locus_tag="TU818_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL0923566.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKHEYERTFTRADISKMMAAE
                     RTKWESEQSAAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            21887..22774
                     /locus_tag="TU818_000729"
     CDS             21887..22774
                     /locus_tag="TU818_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL0923567.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            22786..23142
                     /locus_tag="TU818_000730"
     CDS             22786..23142
                     /locus_tag="TU818_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL0923568.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAIYESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGAVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            23153..23431
                     /locus_tag="TU818_000731"
     CDS             23153..23431
                     /locus_tag="TU818_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923569.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKSRLIKGLAHHKNSTVIYV"
     gene            23428..23772
                     /locus_tag="TU818_000732"
     CDS             23428..23772
                     /locus_tag="TU818_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL0923570.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYSEQQRLLHYRVVSPALYSIYLELGTRKMEAQSFLDPALRKEWP
                     VLMANIKKMFKR"
     gene            23776..24135
                     /locus_tag="TU818_000733"
     CDS             23776..24135
                     /locus_tag="TU818_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923571.1"
                     /translation="MDYSLETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKSRMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            24147..24746
                     /locus_tag="TU818_000734"
     CDS             24147..24746
                     /locus_tag="TU818_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL0923572.1"
                     /translation="MANTKKGTTIEITTGKPIVGKKIFYFIQSVDAPKKSQALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESTGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            24800..25255
                     /locus_tag="TU818_000735"
     CDS             24800..25255
                     /locus_tag="TU818_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923573.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDMDATQIQIIEDMIGRMSNAVS"
     gene            25330..25563
                     /locus_tag="TU818_000736"
     CDS             25330..25563
                     /locus_tag="TU818_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923574.1"
                     /translation="MEGLEYKQLAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            25578..29960
                     /locus_tag="TU818_000737"
     CDS             25578..29960
                     /locus_tag="TU818_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL0923575.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNTFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFQKIIIPVASVIDKIRGNLTGFINQTKMQLQNLVGIGKIRSAFAKAATGVDILTQR
                     ASSKLNNLSAIFETVAGKLPRPFGTAFRKIASSVSTLNSSIQSVGGKISNSLGQQVLN
                     PALQSWNNFFSSVSAKASAFANKVSTSLFGRLTSSLANLSSKIGSSLSNGFSRMSSSA
                     ATSLNGISQKFANTSSAGERLKSTVMSIVQAFSLMAVAQKAMHAITGAIDGAVSRVDT
                     MNRFPKTMALFGYSAEQSKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTS
                     LALAFNNAMIGYGATTEGAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAF
                     GFGKNGVQDLKSVLSDGKITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHT
                     AVVKGVAGMISAFDEAAKANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLK
                     QSINIDFSPLGASVKEVFALINIVFGDFAHTGELSEQAFDNLKAKITSLAPKVIALWA
                     VMNPASAISTIMPLLSLFGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLS
                     GLPGVFATAAGRGLSVLGTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQ
                     IEQLLNTAVTKGPGIIQGLVKGITSKIPVLIASGTQLIAKFANAIAVLLPVIIQAGVQ
                     LITSLVQGIGQNATNLISSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIP
                     LIIQQAQQIIDSFGNSLQANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFV
                     SGIVQFLPQLLQGGIQIIISLVQGIIQNLPQIAQSAVQIIQSLASGLTQALPQIIAAG
                     IQLVAQLAVALIKGLPQIISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQ
                     ITGKSSTSTAKVSADATVMAMNVGMQTTAMANQANTDTTSMLNSISQNTELANINATS
                     NATQMANNVNAQTGTMSLQGLNDSMSLASGISTNMSVANINATTQAREMASGVNGATS
                     SMNLDAINHTLSLASGVGANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLS
                     NSVTSEMSSAATSATSSVNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTA
                     KQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASS
                     AGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLG
                     KAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVG
                     DKIYTAVKEKESREQSKDSYFVFD"
     gene            29972..30814
                     /locus_tag="TU818_000738"
     CDS             29972..30814
                     /locus_tag="TU818_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0923576.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            30824..32806
                     /locus_tag="TU818_000739"
     CDS             30824..32806
                     /locus_tag="TU818_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0923577.1"
                     /translation="MITFLDHRDIEYGVISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAAL
                     KNLALPEEAIKKITEAIKVDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRY
                     NKNLLVGEPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANN
                     KGVKLVLTPTKAKMEPETFTLIKDTEVINVYPLSYSVTLSGDWYKSKQVDLNASEVRN
                     MALGMSYRDVVDGNNADLILDWAENPDIIFDGNGGI"
     gene            32806..33924
                     /locus_tag="TU818_000740"
     CDS             32806..33924
                     /locus_tag="TU818_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL0923578.1"
                     /translation="MSKEVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFA
                     QKKETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKP
                     SSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNA
                     VNIVMRQPTTPNFSSALNITSDNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENA
                     TALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKET
                     SQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            33939..35825
                     /locus_tag="TU818_000741"
     CDS             33939..35825
                     /locus_tag="TU818_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL0923579.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQSTASQISQEIRDREGAVSRVQQSL
                     ESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFS
                     INRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVTNELNNH
                     INKI"
     gene            35837..36274
                     /locus_tag="TU818_000742"
     CDS             35837..36274
                     /locus_tag="TU818_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL0923580.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            36271..36882
                     /locus_tag="TU818_000743"
     CDS             36271..36882
                     /locus_tag="TU818_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL0923581.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQGLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            36894..37166
                     /locus_tag="TU818_000744"
     CDS             36894..37166
                     /locus_tag="TU818_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923582.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA"
     gene            37163..37390
                     /locus_tag="TU818_000745"
     CDS             37163..37390
                     /locus_tag="TU818_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL0923583.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            37507..38841
                     /locus_tag="TU818_000746"
     CDS             37507..38841
                     /locus_tag="TU818_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEL0923584.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLSTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
     gene            39115..>39312
                     /gene="spei"
                     /locus_tag="TU818_000747"
     CDS             39115..>39312
                     /gene="spei"
                     /locus_tag="TU818_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047373492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeI"
                     /protein_id="HEL0923585.1"
                     /translation="MSSVGVINLRNLYSTYDPTEVKGKINEGPPFSGSLFYKNIPYGN
                     SSIELKVELNSVEKAKFFSGKR"
BASE COUNT        12952 a         6831 c         8717 g        10812 t
ORIGIN      
        1 atctttatat aaatcaataa gtgattaaat aaaacattaa aaaaccttgt catatcaacg
       61 tttgttgaag atgtcaaggt tttttcttgt gttttggggc atttttgggg catattatag
      121 ccgatttaag atgtcgacga cttcattttt catgcttttc gtgacgtggg tatagatttg
      181 ttgagtagtt ttcgagtcag catgtccaac tctatccatg atagttttta agggcacttt
      241 gttttctgca aggcgactca ccagggtatg acggaagatg tggctggtga gttctttttg
      301 aatcggtttt tctagtctct tatttgccgc tctgatagag gtgttgaggg cgttgtcttg
      361 aataggaaca ccatttctgg aaatgaagat gtagcccatg tccttgtaat taggattagt
      421 atttttttca agagcattaa ttttcagtat atcctgaata atttcttttt cacgtttggt
      481 tatcaatgtt tcacgccaac tggaatttgt tttaggggtg gttttgatag cgtttctata
      541 gccatttgag gtgtagtcaa gagttccgtg gatttcaatg atatcatttt tgatattgtc
      601 tggctgtata gctagagctt ctccaatgcg gcagccattt aagctcataa attctgccag
      661 ataagccatt ttaatcgatc ctttacgtct atacatttca tctaatagcc ttttgagttc
      721 atctttttct aaaaacttct gggcaacgtc ttcaaagtct ttgatggtct taacaggttt
      781 tgcgagttgg gtactaataa ctggattgat tgagacatac tctaaagcga tagcgtagtc
      841 gaaggtttgt ttgagcagct gccgtgctcg tttacgtttg tcataactac ctggtatttt
      901 gtcgataata ctttgcaggt atttcgtggt tatcttggca atcatcactt ctggatcaat
      961 taagtttcgc aattctctta ttctaaaatc aagagagcgg acagaagttg atttgagtga
     1021 tttctgatga tgttcccacc attcgttcat gacatctagt aggtaggcat cggttgtggt
     1081 aagacttgtt aagattttag atattttttc gtcaagatat ttttgggctt cttttcgtat
     1141 tcgtggcgtg tctttttcca taaggacaga agctctgcac cacttgccag tatacgggtg
     1201 tttgtaccgt tctacaaaat ttacttttcc gcttttgtgt ttttctgacc acattgtttt
     1261 ttacctcatt ttctgttaaa ataggtatag taaagagacc tactgcgaag caggttttta
     1321 ctatactaga tttgcctcac gctcgcaccg accaaaattt gagcgtaggg ctttttttat
     1381 tttacttgat tttctcaaat accattgtag cttgtattct atctccgcca ccaaatcctt
     1441 tactgccacc atttgatgtg gtaatagtgt gtaggcgata tccttttttt gcttgcttat
     1501 taataacatt ttcaagttca gttaaatttc ctgagcctgt tcctataagc ttttctttta
     1561 gtgtaacttg tagcacaaca tattcataat tttcgccaga agcagtcgaa acagtactag
     1621 cttcttttac attgtccaaa aatcccatga taatctcctt taacctatta aagtataata
     1681 ttcatcaatt accatttttt catcggtaat tgtttttaac ttatattttt ccatgaaacg
     1741 agcatagttg aattcattta cattgtctaa ataagataac tcttctttta gcaagtgatg
     1801 aatcatattt ctgtctgctt ctaattcaca cagttctcta tttagttcat actgtctgtt
     1861 ggtatgctct ttatgaccga tttcatgata tattgctttc tttttttcat gatcatcaag
     1921 ataagaacca ataccaagaa ctttgcagtc atggttaaca aacgcttctt tatctgtgcc
     1981 acggttatca taaaataaaa gctcataacc gtgacctttg acatactctt gaagtgataa
     2041 gtccatagtt aatctctatt cttgaatctt tgttctaaga ctgctgcaat gagatcaata
     2101 tcatcatcgg taagtggttt tccatcataa gacattgact gagcagctat ctctttaaag
     2161 tctattgttt tttgactagt ggtgccatta gcaatagcag gattatcagt gcgaccaagc
     2221 aaataatctg ttgaaacatt gaagtagtct gctatttcag caattctttc agcgttgggt
     2281 ttttgagttt tcaacttata gagtgtattt cggctatatt ctaaagtttc ctctagttga
     2341 ataagtgtaa ttccacgctg tttgcacaat tctttgattt tttcaaacgt cggaaacatt
     2401 gatttatcaa cctttctaag gcatgacaaa aaatatttca actttttggg tgaaaaatgt
     2461 tgacaattca accaaatggg tgtatcatat tttttgtaag caagagataa ctaaaaaaac
     2521 aactaagcaa acaactataa aacagttttg gcgaacgagt ttaagttgat ttgttaaggt
     2581 tctttaatat gctttaattc taacttttta ggtgtgagtt gtcaagtggt catatactaa
     2641 aaagttgaaa atttagttat ttcttgttta caaattttaa aacaaggagg aaaaatgaaa
     2701 aaaaacatcg ttgatctaca aaagcgtaaa gagcattttc agtgggtcgc tgatagctta
     2761 gaggggaaag aaaacgaact ttacgtggaa agagattggt acgacaatcc gactcttatt
     2821 tccaaagagg atgcaaaaaa agaagtagag caaatacgac aagaacttat tctacttcaa
     2881 aataaatcat ttattgaata tattttgcaa ttattgcacc aactattcca ccgacaataa
     2941 ggttgattat accgattatc acttttcctg agattgtttc ttgaaaagtg gaaagtaatc
     3001 cagataggtt agttcctctc attttccatt taggggtgtt agtttttaaa tcatcgttga
     3061 tagctaaagt gaggaatgtt gaaaagctat tgaccttgct tgatgttgac atacttagtt
     3121 catggtattg tctcgaagag aaagcgtcag cttcttgttt acctgtcaga aaacgatgtg
     3181 gggttagatt gttcaattca agtaattttt caatatgcgg attgtcaata tatcctccac
     3241 cgtacatctt tttaaacaga taggctaaat cgatcttttt gtcatcatca atgattattg
     3301 gtgtgccgcc tagaactttg aatcgctgct caatagcatg aaagccaaag acagtatctc
     3361 tcatattcca gtgaatccaa tttttgtcgg tatttctgtc aacaaatgtg aagaaatctg
     3421 ttaacagctc tttttcgata gtttcataag tatcatcagt aattggggta tctaatatct
     3481 cggagtactg atgaatggaa aagttgttgg tttgggcatt attgaattga cgaactgaaa
     3541 tggaagctat tctaggactt ttaccaccta gattataaaa actttcgcag gagtaatgga
     3601 taatcagata tttttctggt cgttcttcaa tacttttaag gatagtatta gcgtatttat
     3661 aatcagagta tcgagacatt tttacctcaa gtttttattt ttattatatc agaaaagaaa
     3721 ggagaaaata tgccagatat tgcagttgga cgagaaaaag ttgttacctt cctaaaaagt
     3781 aacaatatca agaagagtga tttagcagca gcctatggtc tcaatcgtca agaggtcact
     3841 aacattctta gtggctcaac tagaggacca aaggctaacc agtttattct gcgagtgatt
     3901 gcagattaca gcattgagta aatgcaaaaa aaaggaactg attgcagtca gccccttatc
     3961 aaaaattcta cttacattat atcacagatt ggaggtaaga aatgccaaaa gctgaattag
     4021 tttacagacc agctaagcaa tctgaaaaag cagaagctgg tgactatgaa cacctttgcc
     4081 aaatctggga aggtttaaca gtcggaacgg ccaaggtttg ggcggcagaa atgagagatc
     4141 acccagattt taaacaattt atcaataatc caacgcatag aattgtattc attgattacg
     4201 aaggtttccg tttatttgtt aaatggaaaa gtcgtaaccg ctataaaccc aagaaggaaa
     4261 ccctggcaga aatgcttgaa aatattaaat tcgaaaaaag agtaggagca taacatgaac
     4321 aaattagaat tatttttatt agtaacaact gttgctttag caattgttgc caggatacaa
     4381 tatgaagtca tcaaaaaaca caactcgcca gagaataagc gaaaaatttt tagggaagta
     4441 gctttagaaa acagcaagaa atggagtgca gaacgttatg tctaaatggg aattacaaaa
     4501 acaactactg gaaaatgcga cagattttga gagcacagtt gaggctttac ttgacttaaa
     4561 cgagtctggc gaaatatctg atctggaact cttactgaac ttaaaggata aattcagaag
     4621 ctattccaaa gaaaaaatac gtatccttaa tgaaattctc aagctaggag gtgcagaatg
     4681 atgacaactt ttgaaaagat tattaagaaa attaatcgga ttgaggggga gttagttaaa
     4741 cctgaagctg aaagacgaga tagcttacct atcctatctg ctcagttggg ttctattaaa
     4801 caagatttaa aattgatgct ttggattgag ctactgacgt taaatgacgt agagagatat
     4861 gaagctcttt atcaaggaaa tgattttaaa ttcagtgaaa ctttcttaga gcgtcaagcg
     4921 acgagaaaag ccttttggag acgattagct aaagaaactt tcaaagaaga ccaggataag
     4981 aggaactttg ttaagttggc tgagaaagaa tttaaaggtg caactttgtc atggcaagaa
     5041 tttttgtggg gtaaaaagaa atgaatatat cactaaaatt tattgatgaa accctagctg
     5101 gcttaaatga tattttacgt cagggggggc tcttgctccc aaaaccaagc cttagcagac
     5161 gcagttttta tactaacagc tttaaaacaa gtaattgagg agagaaaatg aactatttag
     5221 aatacgcact agtttatctt gaacgtgagt tagaaattat tgataacgaa gttatcgaag
     5281 ttgagttgcc gggcggagat tgggagtttg tgcctaatcc ctactacgag aaaggtctac
     5341 atgatagccc acactatcgt agtcaggttg ctaaagacat tcttgatatt aaaggacttt
     5401 tggggaggtg aggctattga ttgcatcaaa aaagacggct taggaaaccg tcaacaatta
     5461 tacacaatta aattataaca cagaaagaga gaaacacaat gattgaagta acttttaaag
     5521 cagagagcat ggcaggtgtt ttcgatgcta tgcgtgaagc tctggatatg ccgaagacag
     5581 taaccaagga tgttgttgaa gaaaaaccag ctcctaaaaa gaaagaagag tctgtaactt
     5641 tgacattagc tgatattaag aaaatggcta aagccaaggt tgaagaaggg aagtcaaagg
     5701 acatcaagga agtcttgaaa gagatgaacg tcgcaaaagt tggtgaactt gaagaatacc
     5761 agtttgctga gtttgttgag aagttggagg ccctctaatg ccagtagaaa atcacgcact
     5821 actgtctgct tctagtgctc acagatggct ttattgccct atgctgccga gattagaagc
     5881 agactatcct agccgcgata ccgtatacac tcaagagggc acaagcgccc atgagctttc
     5941 tgaaatcaaa ctgatgtaca agtctggtaa aatcaccaag cgtaaattta acacgttaac
     6001 caaggctttt aaggaaaact cagacttcta caacgaagag atggaagaga tgacggaact
     6061 ttacacagat attgttatgg agcacctaaa tgcttatgag aacgccgaaa ttgaacttga
     6121 aaaacgggtt gattttagcg actgggtgcc tggcggtttt gggacttcgg atgttgtcat
     6181 tttagcggat ggggtcattg aaattattga tcttaagtat ggcaagggca tgcctgtgtc
     6241 tgctaaccaa aacccacaga tggggctgta cgctctagga gcttatgctt cctacgatat
     6301 ggtttatgac tttgaccgta tcaaaatgac cattattcag ccacgtttag attcggttag
     6361 ttctgttgac atttacgtgg aggagttact ctactgggcg gataatgttg tcttgcctat
     6421 ggccgctcaa gcagacgcag gcattggtga ctggaaccta agtgaaaaag tattgcagtg
     6481 gtctcctgtc gcagctaaat tggtaccaag agcgcaagaa aattgggaat taattgataa
     6541 atatgactat caggagcctg tctatttatc tgatgaagcc gtcgcagaga ttcttgacaa
     6601 agcctcagct atcaagaagt gggttgagtc agttgaagcc tatgccctga aagaagcact
     6661 ctcgggaaaa gaagttccag gctataagat tgttgaaggt agaagtaatc gagtcatcac
     6721 tgataaagac aaagcaattg atattttaca agataacggc tttgacgatg agatttttaa
     6781 accgaaagag ctgttagcaa tgggaactct tgaaaagtta ataggtaaaa ccacttttgc
     6841 tgatttatta gcagaagtaa ttgataaacc acagggcaaa cctgtccttg ttaaaaatag
     6901 cgacaagcga cccgcattaa atagcttaga acaagcaatt aaagattttg aataggagaa
     6961 attataatta tgacaccaaa cacaactaaa gtagtaaccg gaaaagtacg cctaagctat
     7021 gtagctttac tagagcctaa agcctttgaa ggtcaagagg ctaagtattc aacagttatc
     7081 ttaattccaa aaacagacaa agtcacaatc aagaaaatta aagacgcgca gaaagctgct
     7141 tatgaggctg ccaaggacaa taaactcaaa ggggttaaat gggagcgcgt taagacaacg
     7201 cttcgtgacg gcgacgaaga aatggatacc gaagagcacc cagagtacgc tggacacgtg
     7261 ttcatgtcag tgtcaagtaa aactaagcca caaatcattg acaagtataa aaaccccgtt
     7321 gactcagcgg atgaagttta ctctggcgtc tatgctcgcg tatcacttaa tgcctatgct
     7381 tacaacacag cgggaaataa aggaatctct tgcggattaa acaacgtcca aattgttgct
     7441 aaaggagact accttggcgg ccgttcgtca gctgatgcag attttgacga gtggaacgaa
     7501 gaagaggacg aagacgacat tttatagtag agggcctctt tagaggctcc tcatttttaa
     7561 aggagaggta tgagacattt aaatattgat attgaaacct atagttcgaa tgacatcaaa
     7621 aatggggttt acaagtacgc tgacgcagaa gattttgaga ttttactttt cgcttactct
     7681 atagatggcg gagaagtaga gtgccttgat ttgacaaggc agtctctacc tgaagacatc
     7741 aaagatatgt tatttgatga taaagtccga aagcacgcct ttaatgccca attcgaaaga
     7801 gtttgtctca gtcgttacct cggtctacct tactatctag atccttgcca atggcaatgc
     7861 accatggtgc tggcccaaga gttggggctg ccttcaagct tggaaaagtg tgcgctgtat
     7921 ttaaaattag tgcaggaaaa agatacctcg ggtaaaaact taatcagata cttttccctg
     7981 ccttgcaaac caagtaaagc taacggtggg agaactagaa atttaccaga acacgccccc
     8041 gaaaagtggt aaatgtttat tgactactgc atccaagacg ttgttgttga gatggcaatt
     8101 gccgaaaaac tagagtcagt tcctgtgcac gaccgtgaat gggactacta cgcatgcgac
     8161 cagagaatca acgacagagg cgtggcgctt gataaagagt tagttgcttc ggccttgtat
     8221 tgcaaagatg ttaagatgga aagtttgtct ggtgaactaa aagctctaac aggacttgat
     8281 aatcctaata gcagggcgca gttgttaccg tggctaaaag aacacggtta ttcggttaat
     8341 ggtctgacta aagcggatgt tgagcaggag cttaagacgg ccgaaggaga acttaagaga
     8401 gttttagaac ttaaactaca aaccgctatg tcaagtctaa aaaaatatga agctatggaa
     8461 agagctatgt gctcagacgg acgagttcat ggactacttc agttttacgg agctagcagg
     8521 acaggaagat gggcgggcag agttgtccaa gtacagaact tagctaggaa ttatataaag
     8581 gatctagatg atgctagaga gtatgttaaa aagcgtgata ttgatgctgt ggagatttta
     8641 tacgatagtc ttaacgacac tttaaagcag ctagtaagaa cggcactcgt ggccaaagac
     8701 tgctgtacct tctacgtctc tgacttctca gcgattgagg ctagggtgat tgcgtggttt
     8761 gccggagagc agtggaggct tgacgtgttt tcgacgcacg gaaaaatcta tgaggcatcc
     8821 gctagccaga tgttcggaat tccaattgag gagattgata aggaactacg ccaaaaaggc
     8881 aaaatctcag agttggcact tggctatcaa ggaggtcctg gagcgctcaa gcagatggga
     8941 gctctaaata tgggagtcaa ggaagaggag ctccaagggc tagttgatga ctggcgcagg
     9001 gccaataaga aaatcgtcca attttggaaa gatgtgcaga gagccgccat caaagctatc
     9061 aaatcgagag caccaataaa acttggaaaa ctacgattta gataccgtaa aggtttcctc
     9121 tttataacat tgcctagcgg taggaactta gcttatgcaa gagccaaggt tgagccaggc
     9181 gactatggag acaaaatcgt ctatgagggc caaggagata aggcctactt cacagcgcaa
     9241 gagacttacg gcggtaagct tgtcgaaaat atcgttcagg cgacggccag ggatattcta
     9301 gctgaagcgc ttctgaggat tgaagctgca ggctatggtg ttgttttcca cgttcatgat
     9361 gaggctatta tcgaaggctc aggcctgaca atcgaagaag ttaatgattt gatggctcag
     9421 gctcctgaat gggcggaggg tcttccttta aatagcgaag gctacgtaac aaagtattat
     9481 atgaaggatt agatagatga agcaagaaaa actaatagta aagtcttctc ctctgcaaga
     9541 gcttcatatc gcaacgggta attcacgaac agctaagacg tggaaaaata ttacgctaac
     9601 ttggcaggag ctggttgaga ggttagagaa acctacagtc acccaagaga cgtttgcgga
     9661 gtaccagaag atgtctcgag cagaaaaagg gcaagcaaaa gacgtaggag gttttgtcgg
     9721 cgggtggcta aagcagggta aacggaaaaa cgaaaatgtt caaagtaggt ccttggttgc
     9781 gcttgacgca gatagcccaa gtaaagattt cttagatagg ctagacctgc ttgcagacta
     9841 tgcatacgta ctctacagta ctcacagcca ctcaaaaaaa gctgctaagt accgtcttat
     9901 tatccctact gaccgtttaa tgatgcctga tgaatatgag ccagtcgcta ggtacttggc
     9961 taatcaacta ggcatgtcga actttgatga cacgacttat caaagtgtgc gtttgatgtt
    10021 ctggccgagc cactcgagag atgctgactt tacgtttaaa tataacgatg aggcttttct
    10081 aagtgttgat gaggtgcttg atacataccc ggactggcgt gactcaagct tctggccaga
    10141 aagcccgacg cacgctgtta aaagacagcg tgaagctaaa aaacaaggtg acccacttag
    10201 taaaaaaggg cttattggag ccttttgtcg taactatgac attagacagg ccattgcaac
    10261 gttcttgccc gaggtttatg aagaaggaac gactcctgat aggtacacct acactgaggg
    10321 ttcaaccgca aatggcttag tcatctatga tgaagtcttc gcttatagcc atcacgggac
    10381 agatcccgtg ggggatacgc ttgtaaatgc atacgacctt gttcgtatcc ataaattcgg
    10441 agagcaagat agcgaggcta aagatattac tcctactaat aagttgccat caagtaaagc
    10501 gatgaatgct tttgtctctg acttacccga aattaaagac tatttaatgg cggaggcttt
    10561 aggcgatttt gatgaagagt taccagtcga agatgacaga agctggcttg aaattgatga
    10621 gaggggcgaa cctgaggtca atagttattt gctagcaacg cagattatta aggaggttcc
    10681 gatttattgg gacggcttag aatttttacg ctacgacgct aaaaaaggca tctggttgcc
    10741 aaacgcagag gagtatttga agagttatat ctcaactaag aaactcggta aaattactaa
    10801 gattaggcac attagcgaaa ccgtcgtagc gattaaggca caggctttct caagcgaagt
    10861 gtttactgag agcgatctta acaagatagt gctagcgaac ggagtctatg acttgaggga
    10921 taacagtttt aagactaagt ttgatccaga attgcatgca aggtcaagcc atcccgttgt
    10981 ctatgacccc gaggcggcct gtgaaacctt tgagggtttt cttagggaga ccgtcggagc
    11041 tgaaaatata gatttcatct ttgagtggtt cggctataac ttttatcgcg aatatgctat
    11101 ccaaaaaatg ctattcatct acggcagcgg cggtactggt aaatcaacac tgattaatat
    11161 tttacgtgaa atgataggtg ctgataatta ctcagccgtg acactgcagt acctgatgca
    11221 agaacgcttt gcaaaaatcg gcttatatcg aaagactgct aacttcgata ccgatgctaa
    11281 acctcaatac ttagcagatg gcgcaacact taaaatgttg acgggggagg atactattca
    11341 cgcagaccgt aagaataaag agccgattaa cttttacaat tatgctaagc tgtcttttgc
    11401 catgaatgag ctcccaccta tgcgagattt cagcggagga cttaaacgcc gcatgatgat
    11461 cctcgagatg gataaggttt taacgcagga agttaaggcg aaatacccgc tagataagat
    11521 tatgagcgag gtgccaggta tctttaatag ggcgatggag gggcttagaa aggccttaag
    11581 taagagagat ttcagtatta gtgccagcat gagatcaagt gtcgagaaat gggaaaaagg
    11641 caacgatgtc gtggccatgt tccttgaaga cgagtgtgaa cttggtgaag acttcaaagt
    11701 tcctgttagg gatgtctacc cagcctacaa gttctattgt caggattcag gctacaaacc
    11761 tttggcaaaa aatgcattta accaccgact aagagagtta agttatgaaa ataaaaacgt
    11821 taaatctgga ggaaagcaag ccaaaaattg ggtcggtttt aagttaaaaa gtgagtttta
    11881 ggggttactt ttttgggatt agagtttggt aaccctagaa aaaagttacc aagttaccgg
    11941 tttttcaaac tttaaaaata aaaaatttaa aaataatttt taaaaaatca aaactgaatt
    12001 ggaaaaatcg gtaacttagt aactcgaccc ttagaaatgg gctcgaaaag tagccctggt
    12061 agcttattgg tagccctaag aaacctttca tagcaatagc ttagccccta tggttaccaa
    12121 tctaccactt ttcttctatt aacttaaata taaatataaa aaataaatat atataaaata
    12181 aggcatatat aaaacacata tataaaaaaa gagaaaataa gttgaaaaaa acggtaaccc
    12241 tgacctttat tgaccaaagg aggaaagatg aggactgaaa aagacattga aaattatttg
    12301 aaaaagaaaa caaaagggct gtgtttaaaa tttgcaagtc cagggacgat aggagtgcct
    12361 gacagaattg ttgtcatgaa cacgggaacc ttttttgtag aggtcaaagc acctggtaaa
    12421 aaaccaagac ccagccaagt tgccatgcac aaaaaaataa aagaggctgg gcagcacgtt
    12481 tgggttgttg actcctacga atcagtggac atagccttaa aagaaatgga gaactgggtg
    12541 tgagactgca cgagtaccaa gaatacgcta agacatggat agtagagcac ccttattgtg
    12601 gccttttact tgacatgggt cttggtaaaa cgctgacaac actatcggca atagatgaga
    12661 ttcaaaatat tttttccgag gatcataaga ttttaatcgt agcccctaaa aaagtggcgg
    12721 aagaaacgtg gtcaacggag attgggaaat ggcattttga tttcacctac tctaaagttt
    12781 tagggagtga gggaaaacga attgaagcct tagaaacaga agccgatatc tatttgatta
    12841 atcgtgagaa tgttacttgg cttgttgaat actacaagac taaatggccg tttacctttg
    12901 tggttattga tgagctgtca agctttaagt ctagtaagtc aaaacggttt agggctttgc
    12961 gaaaagttag accgaaagtc caacgccttg taggactaac aggaacccca gcgcctaaca
    13021 gtttgattga tttgtggccg cagatttatc tgatggacag aggcgccagg cttgagacga
    13081 gccagactcg atttaaagac aagtattttg ttcctgataa gcgtaatggc ctaatcattt
    13141 acagttgggc acttagggat ggtgcagaag cagaaatcta taacaagatt gaggacatct
    13201 gtatcagcat gaaagctaaa gactatctca agttaccgcc gcgaaccgac aacgttgtat
    13261 cagttaagtt atctaatatg aaagcctaca aacagcttga agctgatttg gtgttggagt
    13321 ttaaggataa ggagatatct gcggctaact ctgcggtttt ggctaataaa ttacttcaaa
    13381 tggctaatgg cgctatctat gatgatgata aaacaacagt tgctatacac gacgacaaac
    13441 ttgacgcgct tgagaatgtc gttgaagaaa gccaaggcca gccaatctta gttttttacc
    13501 agtatcaaca tgatcttgaa aggcttaaga aacgattccc tcaggctgaa gagttgacgt
    13561 cagttgacaa gtggaattcc ggaaaaatac caattcttct gtgtcaccca cagtcagccg
    13621 ggcatgggct taatctgcaa aaaggagggc atattattgt ttggtttggg ctaacatgga
    13681 gtcttgaata ttatcaacaa gctaatgcca gattagacag acaagggcag acagaacccg
    13741 ttattgtgca ccacattgtt gcagaaaata cagttgatga aaaagtactt aggattttac
    13801 aaggcaaaga aaaaaatcag aacgccttac ttgaagcagt taaggcgcag ttaggggtct
    13861 agatgaaaaa agaatatgtc gttagaatct acacgggtag agaaaagaat tttgaggcaa
    13921 aacctcagtt tgaagagaaa acctttacgc gaaaagcaga catgctgagg ttttgggatt
    13981 cttgcgaagc aacagttaaa gaaaaatata ctagggagcg ggagatgaaa aatgaacaaa
    14041 caaaaatttg aaaaattaga caaagtaaaa gaactacttg acgaattgaa aatgtcagaa
    14101 tttatggcgc cacttttagt tggtgatcag attatggaaa ttatcaacga tttgcacaat
    14161 gatccaggac aatttggagc gcaggtattt ctgccatcgc cagacaaaaa atataagttt
    14221 gtagtgcgaa tttgtcgaga agaaaattta gaggattgag ttaacgaaaa tgagggtagg
    14281 ataatggctg aaaataaaac tggaatgatg actttaccaa tcgactatgc aaacagagca
    14341 ttagcaaaag aggaaatact tgatgaactt gttgaaagag aaattgtaga tgtagatctg
    14401 ttaatagagc ttgcagaaga taatccgttt tggatgagtg cattgaattt taaccgaggt
    14461 acaaaatgaa cactaacgaa aaagtaatcg atactatatg tcacatcaga cattgcggtg
    14521 acagatacga tatgtgccaa gacatgcggt cgtgggtagc tgagagaaat ggattaatcc
    14581 aggacttact caaagcaaaa aaacaaattg atcgcaatcg tatcgctaaa cgtctggatc
    14641 gtgcgcagaa aaacatcagt gacattatca caaaagtgac aggcgactta tggcaaggca
    14701 gtgatcaagt cattgctgag cagtgttttt taaaagtatt agaggagatg caaaaatgaa
    14761 cattaaagaa gcgaaaatag gcgataaagt gtgggttgaa ggtattatca attcgtcctt
    14821 ttcaaatggt ggagtacatg taaatcatgc tggtgttgac gccttttatg atcttgagcg
    14881 aacaaaaata aaaccagacg gatacgcagg gcagtcacct aaatatctta aaaatattat
    14941 tgctaaaatg cgagaactac cagagcacga cagagccgtc tggattaaag gtatttttaa
    15001 ggaatttggt attgagaacg acattagcta ttatcttggc cacaagcaag gcgtattaca
    15061 agcaaaggat tcgctaaaac cagaagtact gcagtatgtg gcggattggt atgagaaaca
    15121 taaagataat ttggaatatt acatttggga atatatagcc gaatgggaca atcaagaaaa
    15181 agatgatttt ttcgttttta tgaattttag cgcatttaag cctatccaga cgttagttaa
    15241 catgcatcaa ttcggataca caatcaaaaa agaaaagctg tatacggtgg agatacctaa
    15301 tccgaatgct aagcaaatag ctttgagact tgaaaaatgg gttgaaggaa aagtaagaat
    15361 tgttgcaact tactcatcta ataattttac agattacatg cgcttaacgg aacgagaaat
    15421 ccgaaaagat tttgattggg cgtggcagtt tgcggaagag gtaacgggat gagtagatta
    15481 tctaatgcac agctaaaggc ttttgatgaa tggttgtttg attatcgttt tattgataac
    15541 aagattgcac ttcgaaaact tgagctacaa actgacatga atacagaagt agataaaaat
    15601 atcggtggag gaagagcaaa ttttgtttca aaagttactg aggatgtggt tgcaaggtgg
    15661 gattcagata gggaactaaa gggtctatcc aatttcaaag aagcagttat tgcaacgcta
    15721 aatcttttgg atgaagaact aactgatatt tttaatctta ggtggggcgt cggttcaagt
    15781 aacacttggg aagaaattgc ctatacaaga catctgtcgc gtaagtctat ttaccgcaaa
    15841 agagagcgga ttctagaaat attttccaaa aaaataggaa tgtgacacaa aaatgtatgg
    15901 aattgtcatc tttttgatga taaattggta gtatgagttt gaaggtaagg cagatagtgt
    15961 cttgcctttt tgctatgctt ggaggtgatg gaaaattgag taaattaacc ctaaaacaga
    16021 agcgttttgc agatgagtac atcatctcag ctaacgcgac agcagcggct attaaagcag
    16081 ggtatagtaa aaagacagca aggtcaatag gtcaagaaaa cttgaccaaa cctgacatta
    16141 aagcttatat agacgagcgg cttgaaaaac ttgaatctga aaagattgct acgcaagaag
    16201 aagtcctaca atatctcact tcaattatgc gaggagacca acaagaaaag acgctcatta
    16261 gcgttggaga gtttggtcag aagatagttg acatcgatgt tggtgccaag gatagaatca
    16321 aggcagctga gctactaggc aaacggtaca ggttatttac tgacaaggtt gaaatggatg
    16381 tcagctcaga tgtaaccatt aacgtaggtg agtgggatga cgactaaaca gcgccctaaa
    16441 attaatatcg tgatcaagca tcctagcaaa gtttttaaca aacatatcta cgacaaactt
    16501 tacaactata gcaacttcac ggaagttcat tatggtgggg cgtctagcgg aaagtctcac
    16561 ggtgtttttc aaaagataat tttaaaagca cttaacccta aattcaaaca tcccagaaag
    16621 atattagttc tcagaaaagt cggtgcaact gttagagact ctgtatttgc tgatatcatg
    16681 tctaatttgt cgtatttcgg catcttggat aaatgtaaga taaatatgtc ggcttttaga
    16741 ataacgctcc caaatggcgc agaattcatt ttcaagggta tggacaaccc agagaagatt
    16801 aagtcaatta agggtatatc tgatgtggtt atggaagaag ctagtgagtt tacgcttgat
    16861 gattatacgc agttgacctt gcgtttaaga gataagaaac atctagagaa gcaaatatac
    16921 ttgatgttta acccggtatc aaaagtaaac tgggtttata aagccttctt cgttaagaca
    16981 cctaagaata cagttgtcta tcaaacaact tataaagaca accgcttctt agatgatgtc
    17041 acgagagaaa atatcgagga actagccaat aggaatgaag cttattacaa aatatatgct
    17101 cttggccagt ttgctacact tgataaacta atttttccca aatatgacaa gcaaatatta
    17161 aacaaagaca agttatcaca cttgccttct ttttttggtt tggactatgg atttatcaat
    17221 gatccttcgg cacttttgca tgttaaaatc gatgacgcaa acaagaagtt atacatctta
    17281 gaggaatatg tcaggaagaa tttgaccaat gacgaaatag caaatgctat aaaggacctc
    17341 ggctacgcca aagaagaaat cagaggagat tcggctgaaa agaaatctaa tcaagagctg
    17401 aggaatttag gtattcctag aatgattgat gttaccaaag ggcctggaac cgttatgcaa
    17461 ggaatacagt atttgcttca atatgattgg attgttgatg aaaggtgtgt caagactatt
    17521 gaagaactcg aaaattacac ttggaagaaa gacaagaaga ctaatgagta taccaacgaa
    17581 ccagttgaca gctataacca ctgcattgat gccataagat atgccgtaca agacagaata
    17641 taccagtcgg cggatagaag taagcgcatg aaaaatgcta aatattattt ttaggaatga
    17701 ggtgaaactt tggaagaaaa acaattttta gcaggaactc gttttaatga gaatgctaat
    17761 aagcaattta ttatgctgca agaagacttt gaagcaattg actatgaatc aaaactttgg
    17821 atagatcaac ttaagaatta catttcaagg tttaaagcag aacaattaga gcgtttgaaa
    17881 gagttaaagc gatactatct tggggataat aacatcaagt atagacctgc taaaacagat
    17941 aaatacgcag cggataatcg tattgcaagt gattttgcta agtatattac ggtatttgag
    18001 caaggttata tgcttggcgt tcccgttgag tacaaaaatg aaaataaaga cctccaggca
    18061 gctattgacc ttatgtcggt cagaaacaat gaggactacc acaacgtcaa aataaaaaca
    18121 gatttatcaa tttatggaag agcctacgag ctgttaactg ttgagaaaat agatgacaaa
    18181 aaaaccgaag taaaactcta ccagctcccg gccgagcaaa cttttgttat ctatgatgat
    18241 acataccagc gaaattcgtt gatggccgtt catttctacg acatagatta cggctcaggt
    18301 aaacgtaaac agattatcaa agcatatact tccgacacaa tttataccta cgaagactat
    18361 aaccttgaaa caaaaggtat gcgattaaaa gattatgaag gacatttttt tagaggtgta
    18421 ccagtcaacg aatacgctaa taacgaggag cgaacggggg cttatgagtc tgtacttgat
    18481 aatattgacg cctatgattt atctcaatca gagcttgcta actttcaaca agattcagtc
    18541 aatgcgttgc ttgtaatagc tggtaatgct tacacaggag ctgatgagaa tgactactta
    18601 gatgatggcc gattaaatcc taatggtcgt ttagcgatct caattgggtt taaaaaagcc
    18661 caagtgttaa ttttagacga taatcctaat ccaaatggcg ttaaaccgca agcgtacttt
    18721 ctcaaaaaag agtatgatac cgccggtagc gaagcctaca aaaatagatt agttgcagac
    18781 attttgaggt ttacttttac gccagataca caagatatga aattttcagg agttcaatct
    18841 ggtgaatcaa tgaagtataa gcttatggct tctgacaact atcgcgagaa gcaagagagg
    18901 ttgtttaaaa aaggattaat gcgacgctta cgcttagcag ctaatatctg ggccatcaaa
    18961 gggaatgaag caactacata tagccttgta aatgatacga gtatagtttt cacacctaat
    19021 cttcctcaaa acgataatga aattgttaca gctgcacaaa atctttatgg cattgttagc
    19081 gatcagacta tctttgaaat cttaaatact gtcacaggag tagatgctga agcagagctt
    19141 gaacgcttga aagaagaagc tgataaaaag caatctttac cggagcctag attggtaggt
    19201 gatgctagtg gtcaagaaga accaacggca gaaaagcctt aattactggc aaaagcgtca
    19261 aaaagatatt ctaagttatt tagacagaac tgatttagat gtcttttcag aactgcagaa
    19321 gttatataat gaacaggctt ttgagttaca aaaggaattg tttgattttt atactaagta
    19381 ttctgaagag aacaaaatga cttatcagga tgtcgttaaa aaactacgtc atgaagattt
    19441 atcagattac gtagctaatg ctaacaagta tcgtaaacaa gctgagaaag atcctgagct
    19501 gctaaaacga cttaatgagc agtatgtatc agcaagagct acaaggatgg atgcattaaa
    19561 tcttgagctt gtttatcgtg cggggatact aaaaggtgta cttgattcag catttgaaaa
    19621 tcatttaaaa aaagttgcct catatgctta taaaaaagca atgggtggac ggtcagggac
    19681 aatcaatggt ccagttttag aagaactggt tagaaccccg tttgatggtt ataactattc
    19741 agaacagttg tggggcaata ctgacaatct tgttaagaat cttcaaaaga gattaaaaca
    19801 aggttttgtt cgtggcgagc atcctagagc gatggccaga gatttagcta agcgatttaa
    19861 tgttgctaat cacagggctg aaacactaat cagaactgat ggaactatgg tgattaataa
    19921 tgctaccgct aggcgctact tgaatgcagg acttaagtat tatcgtgatt tagttagact
    19981 tgatgacagg acaactgaga tatgccgtac aattgctaaa gaaaacaaaa gaaagctatt
    20041 atctgagcta aagcctggaa ttaatgtagc accctatcat ttcaactgca gaacaactat
    20101 tattcctgat gaagatgagc taagtattga agtagaacca attgatgata aaagcactaa
    20161 gtattttaag gatgtcacct cagattggat agatggaaat gagcataaac cacaactgtc
    20221 actactaaat gagtacgtaa aaaatggcac tccttacaaa gtagatggcc atagtgtcgt
    20281 tcttgatcat tcgaattatg aatatagagt tgctaattgg ttatccaaaa agacaggatt
    20341 gcaagttgac atggtgccaa gagttaattc ccctgaacat atcaagactc ctgattattt
    20401 agttgatgga gctccttttg atctaaaaga aatcacaggt tcgggtaaaa acgtcattga
    20461 tggcaatcta cgaaaagcaa aaaagcaggc aactaatatc atttttgata taacaaaaac
    20521 ccctttatca tttgaagaga taatggggca attagaacat atttatatga tagatcgtag
    20581 gggtcttgat atatcaatta tcaaaaataa agatgaggta ttagctgtat tagaaaaaga
    20641 aggaggatga cccaccgcct ccacagtaaa ctgcttcatg ggcgttagac catcatcctt
    20701 ctttatctca attatacatc accctattaa aactatcaag gaggaaaata tgtttatttg
    20761 gcaaatggta ttagtggcac taggtgtatt ggtactcata ttgattgttg gcattgcagc
    20821 aatagcggtt aagtcaatta ttgcagaatt gaaaaaagaa ggataaaaca atgaataagc
    20881 gcattaagaa aaaacgtaaa ttggaaacag cggttgtgat gcttgttgca gagaatgcca
    20941 tgcaagcaga agctattaaa aatcaaaaca aacaaatcat ggagctaaaa tcaatcgttc
    21001 aacgaaacgc tctggcaaca aacgaagagt tagcgactgt taaagctgct actttagata
    21061 accaatcagt tatcaaggca attggtgaca cggttgacta tattaagaaa aactacaaac
    21121 ggaagtaggg gaaataaagt ttaaccgtgt cgaatttgac ctctttacaa atctaaacca
    21181 aagtcgtagc aatacggctt tttattgtgt ccaaactttg ttgatgacac taaaagctac
    21241 actgtttcgt cgcaggacgt aaagctagac tatcggttgg tggcgtaacc actaggagaa
    21301 agttatggca gaagaaaatg taacaacaga gacaactgag caagtcgaca ctcaaaaaga
    21361 agctgttgaa catcctaagc atgaatatga gcgaactttt actcgcgcag acatctcaaa
    21421 aatgatggct gctgaacgca ctaaatggga atctgaacaa tccgcagcta ttgaaaaagc
    21481 tcgtacagaa ggtgaacgtt tggccaagtt gtcaaaagat gagcgcgcta aagaggagga
    21541 acaaaaacgt ctagatgcta tcgcagagcg tgaaaaagca gtagcagagc gtgagatgcg
    21601 cattgagacg cattccctgc ttgtggagaa aggattgcca ttggatttta ttgatattgt
    21661 tttagccact actgcagaag aggttaaggc caatattgat aatttacaaa ctatttttga
    21721 taaagctgtt gaaaaacgtg ttaacgatcg tttaactcag aaaccgccac gaactggaaa
    21781 tggctcggtc ggtatgacta aggctgacat catggcgata gaggatgacg acgaacgtat
    21841 gcgtttaatt gctgagaatc gtaacttatt ttaagagggg aatattatgg ctgaaaaaaa
    21901 cttaaacact atggcggact taggagatat taaatcaatt gattttgtta acaagttttc
    21961 caaaaatatt aatgatttac taaaattgct aggggttact cgtcgtgaaa cattaactaa
    22021 cgatctaaaa attcagacct ataagtggga agtgacttta gatcaaactg atcctggaga
    22081 aggggaaaca atccctctgt ctaaggttac tcgaactaaa gataaagact atacagtgaa
    22141 gtggttcaag aaacgtcgtg caactacagc tgaggcaatt gctcgccatg gtgcagctcg
    22201 tgctattact gaagcagata agcgcattat gcgtgagctt cagaatggaa ttaaggatgc
    22261 attctttaca ttcctcaaaa caaaaccaac aaaagttaaa ggcgttggcc ttcaaaaagc
    22321 gctgtctgca tcatgggcta agctagctac ttttaatgag tttgagggtt ccccgcttgt
    22381 ttcttttgtc tctcctttag acgtagctaa ctatcttgga gatactaaag taggtgcgga
    22441 tgcctctaat gtttttggaa tgacattgct taagaacttt ttgggtatgc aaaatgtgat
    22501 tgttatgcca tctgtgccag agggtaaaat ctactcaacg gctgtagaaa atctagtttt
    22561 tgcatcttta aatgttaaag ggggagactt gggcggcttg tttgctgatt ttactgatga
    22621 gacaggttta attgctgcag ctcgtaatcg tcagctttct aatcttacct atgaatctgt
    22681 tttctttggg gcgaatgtac tgtttgctga aattcctgaa ggggttgtag aggcaacaat
    22741 cgaagctgct gctgtacccg gcattggtgg ttaaaggcta tttatatggg tgataaacaa
    22801 cttattgacg atatcaaact ctttataggt atttccaagg gtgatggtgc gcaagatgag
    22861 ctcatcaccc ttgctatata tgaaagtaaa gagcgtgtgc tagctaaact taatgaatac
    22921 tcagaaactg aaatcaccaa aattcctgat agattgaggt ttattgtccg tgatgttgct
    22981 attaaacggt ttaataggat taattcagaa ggagccgttg aagatagcga agaaggaaag
    23041 acttttaagt gggacagtta ccttaaagag tatgaatcaa cactcagaag cgctgctatt
    23101 gggaaggtat attcaggcaa aggggtagca agatttattt aggagataca caatgatcta
    23161 taaagataga gtaatcttag tgtatgtcga tgaacaggac gattttctag ataaaagaac
    23221 tgttgaaaaa cctagcggga aaatcccctg tatggaaaat actttcacaa aatctgaaca
    23281 gatggggcta tttggtaaat atgatttgaa tgcttttaag ttgcacttgc aaggccatta
    23341 cgacggcttt agcaagatta tctacaaggg aaaatcgagg ttgataaagg gactagcaca
    23401 ccataaaaat agcacggtta tttatgtatg agtcttattt atcggatgag aggcctagat
    23461 aggtttttac gcagcgttga gcgcaagcag aagtcagtac gaatcgctgt agataaagag
    23521 cttagtaaat cagctgctag gattgagaga caggctaaaa tactagcccc ggttgacact
    23581 ggatggctga gagctcaaat ctacagtgag caacaacgac tcttacacta tagagtggtt
    23641 tctcctgctt tatattctat ttatcttgaa ttaggtactc gtaaaatgga agcacaatcg
    23701 tttttagacc ctgccctgag aaaagaatgg cctgtgctaa tggctaatat caaaaaaatg
    23761 tttaagaggt gatgcatgga ttactcactg gaaacactat atttaaaaaa ggtaaaaaat
    23821 agattgggag ttttagacat accaatctat tttaaattgc ctaaatcaga cgttttagag
    23881 ccttttattg ttgtaggtac aaatatatca gacttgtcaa aaacagctca aactggagca
    23941 gttattgatg attttagcct gaatatcgat gctttcttac ctggcgatag tcgtttggat
    24001 gcagaagaga taaaatctcg catgcttaga ctgcttgggc gaaataacca aataaaggct
    24061 cagattttgg tagataattc aataggacga gaagtctata gagttgctat caacattaca
    24121 gaaacactat tttaaagggg acctaaatgg caaacacaaa aaaaggaaca actattgaaa
    24181 ttacaacagg taaaccgatt gtaggaaaaa agatttttta ctttatacaa tcagttgatg
    24241 caccaaagaa aagtcaggct ctgttgccag cctatcgtac cgatggtact acaaccatgg
    24301 gtggtgaata cattgatgag caaacccaac aaggtcgcgt tattgagaag gctacagatg
    24361 aacactctat tgatttgaca acgtactttg taccgacaga tccatctgtt gctgtcatcg
    24421 aggaagctaa gaaaacaggt aaatctatca aaatttggga agttattgcc gacgaaagtg
    24481 tcaaagaaca gattcaaatt cctgaatcga ctggacccaa gaaagatgtt taccctgcta
    24541 agtttgggta cgccaagatt gacgaaatcg aacgcggtac tggtatttca gacttagtag
    24601 aaatgtccta caccgctaac attgtagggg ccttacaaga tggtaaattc cctctcacga
    24661 aagaagaaat tgaaatgcta gaaaatgtat acggctatca aaatccgggt gatactactg
    24721 gcgactacga taatatcact aaatagcaca caggggtggc aactgctacc ccattttgat
    24781 ttaaaaagga gataaaataa tggaatttac agcagcaaaa cgaaatatcg atattaaatt
    24841 tgattttaaa actatgttta agatcaataa taaactagga acaattaacc cagaaacagg
    24901 agagcgcaat gcagatggtg tgggtgcttt gtttttcaat atcttagagc gtaatgaaag
    24961 cgccattgtt gaccttgtgc gtttatctgc gggaagcgga aaaaaagcgc taactgaaga
    25021 tgaaattcta gatgcaattg cagaagctgt tgatgaagaa ggaacaacag aagggttgtt
    25081 tgctgagatt gaaaaagaaa tggttgattc tggttttttc agagcgaaga ttttgaaata
    25141 tatcgaaaac atggagaaat cagctcgtta tctcaaagcg aaggacgata tggacgcaac
    25201 tcaaatccaa attatcgaag acatgattgg aagaatgagc aacgcagtat cttagtaaat
    25261 tgcgcacggc tagggctcac agacattgat actatctata aatgtactaa gtgggagcta
    25321 gaggctatta tggaggggct tgagtataag cagcttgctg agcgcgagaa cctctctgaa
    25381 ttgtctctaa agcttagata tacattaaat gctaaaaagg ttgatgtagg taagctcaaa
    25441 tacgataagc ataggctaac tatcaaaaga tcgtatcaaa aagctagccg tagccaagcc
    25501 gatagtgata gcagtattgt tgagagaata caaatgctta ataatcattt tcaaaataga
    25561 tagataagga ggagtagatg ccaggaacat ttgatggttc tattttcgct gatgttggtg
    25621 ccaacacaaa ggactatgag caggccatgg ctcgtattgt tagtacgact cagaatactt
    25681 tcagaaaagc ccaagataca gcggttaaca gtagtaataa aatggttcaa atcattggac
    25741 aaatcatggc ccaactggcg aacaacggcg aatcgctcgg gaagagactt ggctctgcct
    25801 acgctactgg tttaaaactg agcattggtg aaattcaacg catagcagct tccattggcg
    25861 aaaaaattcc cgaacccata aagaatggtt ttcaaaaaat cattattcca gttgcaagtg
    25921 ttattgacaa aatacggggt aacttaaccg gtttcattaa tcaaacaaaa atgcaacttc
    25981 agaatcttgt gggtattggt aagataagat ctgcatttgc caaggctgcg actggagttg
    26041 atatcttaac tcagagggca agtagtaagc ttaataactt atctgcaata ttcgaaacgg
    26101 tcgcaggcaa gcttccgcga ccattcggaa cagcgtttag aaaaattgcc tcatccgttt
    26161 ctaccttgaa tagctctata cagtctgttg gagggaagat ttctaattca cttggtcagc
    26221 aagtcttgaa cccagcctta cagtcatgga ataatttttt tagttctgta tcagctaagg
    26281 cgtctgcttt cgcaaacaaa gtgagtacta gtttgtttgg tcggctgacc tcaagtttag
    26341 ctaatttatc aagtaaaata gggagcagtc ttagcaatgg ttttagcaga atgtctagtt
    26401 ctgcggctac ttccttgaat ggaataagcc agaaattcgc caatacctct tctgctggag
    26461 agagactcaa aagtacagtg atgagcatcg tgcaggcctt tagtttaatg gctgttgctc
    26521 aaaaagctat gcacgctatt actggggcaa tagacggggc ggttagtcgc gttgatacca
    26581 tgaaccgctt tccgaaaacg atggcgctat ttgggtattc tgctgaacaa tctaaggcat
    26641 caattgataa gctatcaaaa ggaattgaag gtctgccaac tcctctagac agtgctgtaa
    26701 aaagcgctca acagctcgcc ataaccacag gaagtttaga taaagggact agtttagccc
    26761 tcgccttcaa taacgcaatg atcggttacg gggcaacaac tgaaggggct gagcaagcac
    26821 tcaggcagtt taaccagtcg ttggggtctg gaaaaattca agctgaagag tttaactctg
    26881 tatcagaagc tgcgccaggt ttaatgtcta aaatggcgga agccttcggt tttggtaaaa
    26941 atggcgtaca agatttaaaa tcagtcttat ctgatggcaa aatcactgca caagagttcg
    27001 cagataaaat gattgagctt aacgatgccc aaggcggatt tgcagagatg gcccaatcat
    27061 cggctggtgg aatccgaact gcatggaaga acgtacatac cgccgtcgta aaaggcgtag
    27121 caggtatgat ttcagccttt gatgaagcgg ctaaagctaa tggcatgaag accattgctg
    27181 aaacacttct tagtctgaag ccagcaataa ccagtgtttt tgatacgatt aattctctta
    27241 ttccaaatgc agttgcagca ttcgctaggc taaaacagtc tatcaatatt gactttagcc
    27301 cattaggcgc cagcgttaaa gaggtgtttg ctcttattaa tattgttttt ggagattttg
    27361 cacatactgg tgaattatca gagcaggctt ttgataatct aaaagcaaaa atcacttctt
    27421 tagctcctaa agtcattgcc ctttgggcag tgatgaaccc cgctagcgct atatcaacga
    27481 taatgccttt gctttctcta ttcggaaaag ttggtctagc tttaggaagc ttagggactt
    27541 ctgtcggggc gtttggcggc ataatttcta gtgggatagc tagtgccagc ggcgttgttg
    27601 gtgcctttgc ggcaactcta agcggattac ctggcgtttt tgctaccgca gcagggcgtg
    27661 ggctatctgt gcttggaact atgacaagcg caatgtccag tcttgtgagt ttagcactgg
    27721 cggccatagg accggccgct attctaggtc ttgtggtggc aggacttggt ttgattaata
    27781 gtcagtttgg cgcacaaatc gagcagctac ttaacaccgc agttacaaaa ggtcctggca
    27841 ttattcaagg ccttgtaaaa ggaattactt ctaaaatacc agttttgata gctagtggca
    27901 ctcaattgat tgctaaattt gcaaatgcta tcgcagtgtt attaccagtt ataattcaag
    27961 ctggcgttca gctaattacg agtctcgtcc aaggtattgg acaaaatgca acgaatttaa
    28021 ttagttcagc aataaaaatc attggtagtt ttgttagttc aattgcgagt gcattgccgc
    28081 agcttatttc tgttggaatg gagctattat taaatgttgt caacggcata gttcaaaata
    28141 tacctcttat tatccagcaa gcccagcaaa ttattgatag ttttgggaat agtttacagg
    28201 ctaaccttcc tagtattatt agcaacggta tagctatttt ggtgaatctt gtacagggaa
    28261 ttactcaaat gttgccaact gttctgcaga tagctactca agtcattacg agttttgtat
    28321 ctggaattgt acagttttta ccgcagttac ttcaaggtgg cattcaaatc attattagcc
    28381 ttgtgcaggg gattattcaa aatctacccc agattgcaca atctgctgta cagattatac
    28441 agtctttagc ttctggactg acgcaagctc tacctcagat tatcgcagca ggcattcagc
    28501 ttgttgcgca actagccgta gccttgataa aggggcttcc acagattatt tctgcgggta
    28561 ttcaattaat tatggggctc ggtaaagcca tgttaggggc tatcccaaac gctctttcag
    28621 gagtttggga aggtattaag agcggattca gttcgatgtg ggaccaaatc acaggtaaga
    28681 gttccacaag tacagctaaa gtctctgcgg acgccacggt catggccatg aatgttggga
    28741 tgcaaacgac agctatggct aatcaagcta atacagatac gacatctatg cttaatagca
    28801 ttagtcaaaa tacagagctt gctaatataa acgctacatc aaatgccaca cagatggcta
    28861 ataacgttaa tgctcagaca ggaacgatga gtcttcaggg gttgaatgat tcgatgtctc
    28921 ttgcgagtgg cattagcact aatatgtctg tcgctaatat aaacgctact actcaggctc
    28981 gagaaatggc ttcaggggtt aatggtgcga cttcttcaat gaatctagac gccattaatc
    29041 atacgctcag cttagctagt ggtgttggtg cgaacatggg agctgctagc acaggtgcaa
    29101 cttctcaggc gcaagctatg agctcagggg tgagtaacag cctggcatca atgcagtcaa
    29161 actcaactaa agcagcctct ggtctgtcta atagtgtgac aagcgaaatg tcttctgcag
    29221 caacctctgc aacctcaagc gttaataggt tgtcctcggc ggtcgagtct ggcttcaata
    29281 aggcgaagac ttcagcaaca acctcaatga atgggatagc caatgcggtt aaaacaggat
    29341 ttagtagcat taacagtact gcaaagcaat ctatggcaaa ccttgtaagt tcagtgactt
    29401 ctgggatgtc tcgtgcaacc gcggtgtcta ataatgcttg tcagaagatc ctctcaatat
    29461 tcagggcttt ggcagggcag atgtcttctg caggagctta tgcaggtcaa ggttttgcta
    29521 atggtctagc tagtagcgca ggcacaatct acgcaatagc taacagcatt gccgctaatg
    29581 tagcagcaac aattagacgc gctttagata ttcactcacc atctcgtgtc actaaaacac
    29641 taggtgcatt tactggagag gggtttgccc tcggtatggc agagtggata ggtgagatca
    29701 atagcctagg taaagcatac gcaacagcag ttactgatca aaactggggg gtaaatagta
    29761 ctgtttcaac atctgctaaa gttaataata gtggaatcaa tacctctctt gataatctta
    29821 gcgaagaggt taggcagtct caattgtcag agcctatctt tgaagtgcat aatgagattg
    29881 ttggagataa aatttacacg gctgttaaag aaaaagaatc aagagagcaa tctaaagatt
    29941 cttattttgt ttttgactag aagggagtat tttggattta ttaatagaaa aagagagtca
    30001 ggcaactagg ttgtctgact ttggtattta taatattgct attgaagata gcgctccttt
    30061 actatctgta tcacaccgag cagtcaaagg aaggagtggt tacatctacg atggggctac
    30121 ttttacgact aaaacgctta aggtcaaagg aagagtgacg gtaagcaacg tggaaagact
    30181 tttggacaaa caggacgaac taaacgctct gcttgttgtt gacgaacctt tctacgtgac
    30241 taagatgtac cctgaaaact cagatctatt taactttgag cttccagggg aaagcacagg
    30301 agacctgcaa cttattggct ctcctcataa accttggaaa tatagattta aagtcatctt
    30361 agacgacact atcgcttatg aatttatagg aaaaaccagt caaggactaa aatataatct
    30421 ttccttcgcg ctaagaactg ctgaattacc tttcggtgag acaaagccaa aggacataac
    30481 tctatcaggg ggcagttttg cctatgcagg aaccgctaaa gcaagtcagc tagagtggcc
    30541 ttttattata gagcttactc cttctggagg tcagactaat ttttatattg aaattgatgg
    30601 caggcgcttt gagtttaagc agaatagcca gctacaaaat agtgataaat tacttttgac
    30661 aggcatagct accacactaa acggaaatta tgtcaatgct aaaacgaact atgagtattt
    30721 tatcttcaat cctaatccta acaagagaat tacttacaaa acggattttc ttggcacgat
    30781 taggatttta aattttgtag agttgtataa atagggaggt ctaatgatta cttttttgga
    30841 tcatcgtgac attgagtatg gggtcattag tgtcattagg catactaatg ctgttaatgg
    30901 tgagcgctca gtgagcgggg aaatttatac aaacagtgat gtcctcaata atatcgatag
    30961 agggtggcga cttagatttg aagatgagta ttacgttgtt atttacgcaa agcctgttga
    31021 tgttggtcaa aaaacgcaag tttcgtttga tgccatacac caattttttt gggacttcag
    31081 caagagtagt atctatgagg gtctcggaga tgggtctcat accattgata cctatctaga
    31141 gacagtattt aaaggtagtg ggtaccgcta taagctagaa gtaggtgtga acgcatttag
    31201 aaaacaatct tttaattata agtccaggtt agatttattc aatgagatta ttaaagcgac
    31261 cggacttgaa ttttcagtca gcgggaaagt tgttcggcta ttaaaaaaca taggtactga
    31321 tctgtcaaca gtggtacgaa aaaatttcaa catgaatgac cttaccattg aaaagaatat
    31381 tgatagcttt attacctatc agaaaggctt tggtgcatgg accgacccag aggaccactc
    31441 taaggggaga cttgaggcgg aatacgaaag tcctcttgcc aaggagtacg gtcgacttga
    31501 aggggcgcct ctgacggatg agcgcttcac ggtggcagat aatctaaaag aagctttaaa
    31561 aagtaatgtt gaaaattcat ataagatatc agtaaaaatt gatatggaag atttaacgag
    31621 agctgggtat agatgtgaga ggccggttgc tggtgactac attatggcga taaatgagac
    31681 tttaggtttt caagagcgta tacggatagt ttcttttaca agctactacg acgcaactgg
    31741 agctttagta aaacatgaag tcacttgtaa tgatatcgga tctgtgaaaa aacaaagcgt
    31801 aggaagtctg tctataaaca gtagaatcaa tcagatagat gcagatattg cttctgcaat
    31861 tgaagtagca acacaagcac tagtatctgc tgacgggaaa aatactgttt acggtggcac
    31921 agaaatgccc aaagatgaac caaaaggaac cttaaaaaaa ggagacatat tattcctaaa
    31981 agttggcgat actactagaa tgtatttctg gaatggtgct gagtgggaag aacctgaggt
    32041 tgtgaacgac ccagaacgat ggcgtgaaga cctcgaaaaa caaatctctg aggcgatcga
    32101 aaaagccaaa aaagcacagg aagaaatcaa ccaacgcacc gataaagagc ttgaagaatt
    32161 tagagccgcc ctcaaaaacc tagcgttacc agaggaagcg attaaaaaaa tcacagaggc
    32221 tataaaagtt gatgacatcc cgtctattaa acaaagcttt gatgacctca aaaatagagt
    32281 gagtgagaca agcgaagaat ctcgtttaac tgccgaaatt ttagggaaca acggtaagac
    32341 acgctacaac aaaaatttgc tggtcggtga gcctaatcgt gttaaaaaaa ttgatgagga
    32401 ttttatcgag gtagaagcta atgatggtgg tttcaagcgt ggcgagactt acacaatcag
    32461 ctttagtcag acatgtgagc cgctcaaaaa agtggctatc acgctgatcc aagctaataa
    32521 taagggagtt aaactggtac tgacacctac taaggcaaaa atggagcctg agacttttac
    32581 tctaattaag gacacagagg tcatcaacgt ctatcctttg agctactcag tcactttaag
    32641 tggtgactgg tacaaatcta agcaagtaga tttaaatgcg tcggaggtgc gaaatatggc
    32701 tctggggatg agttatagag atgtggttga tggtaataat gctgatttaa ttttggactg
    32761 ggcggaaaac ccagatatta tttttgacgg aaacggaggt atttaatgtc aaaagaagtt
    32821 gcatcagcaa ggatacagca tagaggcatg accaaacaag agtgggaatc aagctccgat
    32881 atcttaatgg agcgagaaat tggaattgat atgactacgg gttacccaaa agttggtgat
    32941 ggcaaaaata agttcaagga cttaaaagac ttgcgcggcc ctatgggacc tcaaggtcct
    33001 tcaggagaaa gaggcctaac tggcccaatt ggtcctcggg gccctgctgg caagcctgga
    33061 acgacagatt ataatcaact ccaaaataaa ccaaatctag atgcgtttgc acaaaaaaaa
    33121 gaaactaata gtaaaatcac caaattagaa tcaagcaaag cagataaaag cgctgtttac
    33181 tcaaaagcag agtcaaaaat agagctagac aaaaaattga gtttgacagg cggcatagtg
    33241 acaggacaac tacagtttaa acctaataaa agtggtatta aaccctcatc ttccgtagga
    33301 ggagcgatta acattgatat gtctaaatcg gaaggtgctg gtgttgttgt ctattctaac
    33361 aatgatacca gtgatgggcc gttaatgagc ttgcggacgg gtaaagagac cttcaataaa
    33421 tcagcgcttt ttgtcgatta taagggaaca acaaatgccg ttaatattgt gatgcgtcag
    33481 ccaaccaccc ccaatttttc atcggcgctt aatattacta gcgacaatga aaatggtagt
    33541 gcaatgcagc tacgagggtc agaaaaagcg ctaggaacgc tcaaaatcac acacgaaaac
    33601 ccaaacgttg aggcaaaata cgatgaaaac gctacagcgt tatctattga tatcgttaaa
    33661 aaacagaaag gcggaaaagg tactgctgct caaggaatct acattaactc aacatcaggc
    33721 acgacaggga agttgcttag gattagaaac cttagtgatg ataagttcta cgtcaagtct
    33781 gacggtggtt tttatgccaa ggaaacttcg cagattgatg gcaacctgaa actcaaggac
    33841 cccacagcga atgatcatgc ggcaaccaaa gcttatgtag ataaagcaat ttctgagtta
    33901 aaaaaactca tactaaaaaa atagattaag gaggataaat gagcagagac ccaacactta
    33961 ttttagacga gtcaaacctc gttattggta aggatggacg tgtgcattac acatttaccg
    34021 cagaggacga caacccaaaa gtcagactag ctagcaagtg tctaggcaca gcgcatttta
    34081 atcagctcat gattgagcga ggagaccaag ctactagcta tgttgcgcca gtagtagttg
    34141 agggtacagg taatccgact ggactattta aagacctcaa agagattagc ctagagctga
    34201 cagatactgc taattcccag ctttggtcaa aaatcaagct gactaaccgt ggtatgttgc
    34261 aggaatacta cgacggtaag atcaagaccg agatagtcaa ctccgccaga ggtgtcgcta
    34321 cacgtatcag cgaggatact gataaaaagc tagcgctcat caatgacacc attgatggta
    34381 tcaggcgtga gtatcgagat gctgatagga agctatccgc aagctatcag gcaggcatcg
    34441 aggggctaaa agccacaatg gccaatgata aaatcggttt acaagctgag attaaagcct
    34501 cagcacaagg gctatcgcaa aagtatgatg atgagttgcg caagctatcg gctaagatca
    34561 caacaacctc aagcggcact acagaggcct acgagagtaa gcttgcgggc ttacgtgctg
    34621 agtttactcg ctcaaatcaa ggcacgagga cagagctcga gtcacaaatt agcgggctaa
    34681 gagcggtaca gcagtcaaca gctagccaaa tctctcaaga gattagagac cgtgaaggtg
    34741 ctgtcagtcg tgtgcagcag agtttggaga gttaccaaag gcggatgcag gacgcagaag
    34801 aaaactatag tagcttgacc catacggtta gagggctaca gagcgacgtt ggatctccga
    34861 ctggtaaaat ccaatcgcgc cttactcaac tagcaggaca aattgagcag cgggttacta
    34921 gagatggtgt catgagtatt attagtggcg ctggagacag cattaaatta gctatccaaa
    34981 aggctggcgg cattaatgcc aaaatgtctg gtaatgagat tatctcagca attaacctca
    35041 actcctacgg agtaacaatc gcaggtaaac acatcgctct cgatggcaat acgactgtca
    35101 acggcacctt taccacaaag atagcagagg ctatcaagat tagggctgat cagattattg
    35161 caggcacgat tgacgctgct aggattagag tgattaacct taacgcaagt agtatcgttg
    35221 gtttagacgc taactttatc aaagctaaaa ttggctatgc tatcactgat ttgctcgagg
    35281 gtaaggtcat taaggctcgt aatggagcga tgcttatcga cttaaataca gctaagatgg
    35341 actttaatag cgatgccaca attaatttta atagcaaaaa caatgcctta gtacgtaaag
    35401 atggcacaca tactgccttt gtacatttta gtaatgcgac gcccaaaggt tatacagggt
    35461 cagcgttgta tgcatcgatc gggataacct catctggtga cggtgttaac tcggcttctt
    35521 ccggtcgttt tgcagggcta aggtcattta ggtacgctac gggatataat catactgctg
    35581 cagtcgacca aaccgagcta tacggtgata atgtcttgat tgcagatgac tttagcatca
    35641 atcgaggatt taaatttaga ccagacaaga tgcaaaaaat gcttgacatg aacgacttgt
    35701 atgcggctgt agtagcctta ggccgctgtt gggggcactt ggctaacgtc ggctggaata
    35761 ctgctcatag caattttaca agtgcggtca ctaacgagtt aaataatcat atcaacaaaa
    35821 tttaatagga gaaacaatgg atttaacgct taaaaacaaa gatttaaaca cactatatag
    35881 tgtactagac aaaatcaaag tcacgaacat gcgagcaaac cgcggacgtg ctaagctact
    35941 cgcaaaagta gtcgataaat tcaaagagta cgccaaggat gagggtgacc ttattgatct
    36001 gtatgctcaa aaagacaaag atggcaagtt tgtcattgat gagcacaaaa acatcaagct
    36061 agcagacccc gctaaactcg acgagttcaa cggcctactc aacgagctag ctgatgaaga
    36121 aattgtgatt aaagggggtg agtactccaa gcgatttatt gactttttaa actttttaga
    36181 agagtgtgaa gatgaattta catcatctga aatcattctt atcgacaaca ttttggaaca
    36241 atttgaagaa agtaaaaaag gagaaaaacc atgagaaatt ggaaagtgac aggaaaatac
    36301 ccacaatttg acagcacagg agcagtcgca agcacacata ttattatcac tgctgaggat
    36361 ggctcagtca tctctcaacc aatcaagcag ggcttaactt caactaatga cacagagatt
    36421 atcaaagcta ctttggaaga atttaaaaaa tctgaatacg tcgaaatcgc tatgggcgaa
    36481 gccgtgcaaa aagtagacga ccttgaaaaa atctcacagg aaaccgctaa gaccgctaaa
    36541 acagcccaaa cagccgcagg attagctaag gtgtccgcag agcgtacaca gcggatgatt
    36601 aacttgcaaa ccatccacgt attgacaagt ggtgggaaag ttgaacccga tatctacaaa
    36661 ggtatgttag agcttattga acctgctaaa caaggcgagt atcaggctta tgacgtgttt
    36721 actgttgtag atgagtcgca cgaagatcaa gcgggagaag gtaatcttgt ctttgtacac
    36781 gttaacgagc cgtttactta tgacaaacag acgcttaaag agctagagga agaggataaa
    36841 gtcacagtca ttaagtatgc ggacttagtt aagcaggatt agcgaggtaa gctatggcaa
    36901 cagagttgat atttggtctt ggtggcttta ttttagctat cgtcacgact tacaatattt
    36961 ttaatgcaaa atccatcaag catgcgacag atattacttt gttgcagtct gaagtagagc
    37021 atttaaaaat tgttacacgc caaaatgctc ggcgtcttga ggagcatgat gagcaaaaca
    37081 aaacgctcat cacaatgaca gagcaaatta aaaacctcaa tcgtgaggta agagaactta
    37141 aagatattat gagaggtgaa gcatgatcaa tttaaaatta cgactacaaa acaaagtaac
    37201 cttgatggct attttaggag ctatcttttt actggcacag caattaggta ttaaactacc
    37261 atcaaacatc gcggatattg caaacacagc tgtaacgctt ttggtattgc tcggtgttgt
    37321 cacagatcca accacgaaag gcctgtcaga cagtgagcaa gctttgactt accacgaacc
    37381 aaaacaatag gaggggacat gcgggcaatc acacgattag cattagttat agcaatagca
    37441 atactgtatg tgccattatc tgttgttgct ttgattttaa gcccattttt agataaggag
    37501 ggataaatgg ctacatatca ggaatataaa agtcgttcaa atggcaatgc ttacgatatt
    37561 gatggatcgc ttggtgcgca atgttgggat ggctacgcag actactgtaa gtatctagga
    37621 ctgccatacg caaactgtac aaatacagga tatgcaaggg atatatggga acaacgtcac
    37681 aaaaatggta ttttaaacta ctttgacgaa gtagagacta tgcaagctgg agatgtcgca
    37741 atttttatgg tagttgcagg tgttacaccg tatagccatg tggctatttt tgatagtgat
    37801 gcaggtagtg gatacggatg gtttttaggt caaaaccagg gtggagcaaa cggagcatat
    37861 aatttagtaa aaataccata ttcaacgact tatcctactg catttagacc aaaagttttt
    37921 aaaaatgcag ttactgttat aggtaatata ggactaaata aaggcgatta ttttattgat
    37981 gtatcagctt atcaacaagc agacttaacc gctacttgtc agcaagctgg cactactaaa
    38041 acgattatca aagtatccga gtcactcgct tggctgtctg ataggcatca gcaacaagct
    38101 aatactagtg accctattgg ttattatcac tttggacgat ttggaggaga tagcaactta
    38161 gcgcaacgag aagcagattt atttctgtcc aatttaccaa ccaaaaaagt ctcttactta
    38221 gtcattgatt atgaagactc tgcaagtgcc gacaaagaag ctaacactaa tgcagttatt
    38281 gcgtttatgg ataaaattgc aaacgctgga tataagcctg tttattacag ctataaacca
    38341 tttacgctta ataatattga ttatcagcaa attatcgcta agtacccaaa cagcatttgg
    38401 atagctggtt atccagacta cgaagtacga acagagccac tttgggagtt cttcccttca
    38461 atggatggtg tgcgctggtg gcagttcaca agtgtaggag tagcaggtgg tttagataaa
    38521 aatattgtat tattagcaga tgatagtagc aaagtggata tacctaagat tgacaaacca
    38581 caaagccagc ttacttttaa tcaaaagcta gatactaaca ctaaattaga caactcgaat
    38641 gtaccttact acgaagcaac ccttagcaca gactattatg tagagtctaa gccaaacgca
    38701 agtagcgctg ataaagaatt tatcaaggca ggaactcgtg taagagtcta tgaaaaagtg
    38761 aatggatggt cacgtattaa cgcttctcag tctgaccagt gggtcgaaga taagtattta
    38821 tctaatgcaa cacaagtata aaataggagg taaagctcct ttagataaga caaatgccct
    38881 cgcttttgcg ggggctgttt ttgttataaa gattttaatt gttatttaag cattttcgtt
    38941 gatttttttc ttttttgtgc taaaatattt tgtgatttct tattattaaa gaagaatagg
    39001 gtacacttat aagtgagaaa aattgtaaat gttaatttta aaaagttttt aacttcatct
    39061 tttctattgt gggtatttat atcagctata attccaacgt gttacgcgta tgagatgagt
    39121 agtgtgggag ttattaattt aaggaattta tactctacat atgatccaac agaagtaaaa
    39181 ggaaaaataa atgaaggtcc gccattttca ggtagtttgt tctacaaaaa tattccttat
    39241 ggcaatagtt cgattgaatt aaaagtagaa cttaatagcg tagaaaaagc taaatttttt
    39301 tctggtaaaa gg
//
LOCUS       DARYMD010000016        39075 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYMD010000016 DARYMD010000000
VERSION     DARYMD010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39075
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            110..637
                     /locus_tag="TU818_000748"
     CDS             110..637
                     /locus_tag="TU818_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL0923586.1"
                     /translation="MSVDDYRPTYAVEAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVIMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            637..1755
                     /gene="yqeH"
                     /locus_tag="TU818_000749"
     CDS             637..1755
                     /gene="yqeH"
                     /locus_tag="TU818_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL0923587.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALVKGIEAREIYCQRCF
                     RLRHYNDITDVHITDEEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            1782..2123
                     /gene="yhbY"
                     /locus_tag="TU818_000750"
     CDS             1782..2123
                     /gene="yhbY"
                     /locus_tag="TU818_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL0923588.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNILFKVSAKKD
                     NRKLSVKVKSI"
     gene            2207..2839
                     /locus_tag="TU818_000751"
     CDS             2207..2839
                     /locus_tag="TU818_000751"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL0923589.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYIHKEGLYQ"
     gene            2836..3429
                     /gene="yqeK"
                     /locus_tag="TU818_000752"
     CDS             2836..3429
                     /gene="yqeK"
                     /locus_tag="TU818_000752"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL0923590.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLDPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            3431..3784
                     /gene="rsfS"
                     /locus_tag="TU818_000753"
     CDS             3431..3784
                     /gene="rsfS"
                     /locus_tag="TU818_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL0923591.1"
                     /translation="MRKEELLEIVIKAADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEASGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            3914..4657
                     /locus_tag="TU818_000754"
     CDS             3914..4657
                     /locus_tag="TU818_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0923592.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            4767..5867
                     /locus_tag="TU818_000755"
     CDS             4767..5867
                     /locus_tag="TU818_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL0923593.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLLD
                     YQKLSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPFLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHTDMPEQTWGCVPIRPEAMN"
     gene            6223..6930
                     /locus_tag="TU818_000756"
     CDS             6223..6930
                     /locus_tag="TU818_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL0923594.1"
                     /translation="MKTVKEVSQLTGLSVRTLHEIGLLPPTMVGENGYRFYDAAALRR
                     LQDILLFRELAFPLKTIKQLLDSPSYDQQAALAAQIKMLELRKAHLEKVIAHARTLQK
                     GEETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIFSIF
                     GRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDHMGG
                     AGTAAFVSRAISYYCQH"
     gene            7071..7787
                     /locus_tag="TU818_000757"
     CDS             7071..7787
                     /locus_tag="TU818_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0923595.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            8009..8854
                     /locus_tag="TU818_000758"
     CDS             8009..8854
                     /locus_tag="TU818_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0923596.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSVKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            9226..10071
                     /locus_tag="TU818_000759"
     CDS             9226..10071
                     /locus_tag="TU818_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL0923597.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKALIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            10149..11519
                     /locus_tag="TU818_000760"
     CDS             10149..11519
                     /locus_tag="TU818_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL0923598.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVSLGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKEHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHF
                     KYGGVIESAAWYLLQALSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATPKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAISQLIAAAQPFYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSCDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            11512..12576
                     /locus_tag="TU818_000761"
     CDS             11512..12576
                     /locus_tag="TU818_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL0923599.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLPKAERERKVTELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            12577..13269
                     /locus_tag="TU818_000762"
     CDS             12577..13269
                     /locus_tag="TU818_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923600.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TU818_000763"
     CDS             complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TU818_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL0923601.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGDYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPILYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDGLSYFFERLVPLGQFSMGWISFSILGFVLGLII
                     SKTKGLHPTAS"
     gene            15127..16341
                     /gene="sstT"
                     /locus_tag="TU818_000764"
     CDS             15127..16341
                     /gene="sstT"
                     /locus_tag="TU818_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL0923602.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(16695..17369)
                     /locus_tag="TU818_000765"
     CDS             complement(16695..17369)
                     /locus_tag="TU818_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL0923603.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(17379..18755)
                     /locus_tag="TU818_000766"
     CDS             complement(17379..18755)
                     /locus_tag="TU818_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL0923604.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALVIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(19278..19991)
                     /gene="rsmG"
                     /locus_tag="TU818_000767"
     CDS             complement(19278..19991)
                     /gene="rsmG"
                     /locus_tag="TU818_000767"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL0923605.1"
                     /translation="MTPQAFYLVLEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKKPL"
     gene            20127..20684
                     /locus_tag="TU818_000768"
     CDS             20127..20684
                     /locus_tag="TU818_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL0923606.1"
                     /translation="MPMFLVIVALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANHEEKTLEKITSLRSRVADATTPQATMAASNELSKQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLESFPSNLVAKL
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            20721..21614
                     /gene="htpX"
                     /locus_tag="TU818_000769"
     CDS             20721..21614
                     /gene="htpX"
                     /locus_tag="TU818_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL0923607.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPRVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDNDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVALTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            21902..22435
                     /locus_tag="TU818_000770"
     CDS             21902..22435
                     /locus_tag="TU818_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL0923608.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLIRDPQVIDINNVRASGR
                     AQFDDGLYLLEYQLGYQITLPSSRSMAPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTEAEKESQILPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
     gene            22620..23306
                     /gene="covR"
                     /locus_tag="TU818_000771"
                     /gene_synonym="csrR"
     CDS             22620..23306
                     /gene="covR"
                     /locus_tag="TU818_000771"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL0923609.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            23310..24800
                     /locus_tag="TU818_000772"
     CDS             23310..24800
                     /locus_tag="TU818_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL0923610.1"
                     /translation="MAKQKKYKKTLPKRLSNLLFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERNI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAQEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            24991..25485
                     /gene="nrdR"
                     /locus_tag="TU818_000773"
     CDS             24991..25485
                     /gene="nrdR"
                     /locus_tag="TU818_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL0923611.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            25469..26632
                     /locus_tag="TU818_000774"
     CDS             25469..26632
                     /locus_tag="TU818_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL0923612.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKELLL
                     TLARMNFLDEVINIMVLYTFNKTKSANLHKTYLMKMANDFAYQRVLTAETAIIKTRAF
                     GERKQQAKSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            26633..27541
                     /gene="dnaI"
                     /locus_tag="TU818_000775"
     CDS             26633..27541
                     /gene="dnaI"
                     /locus_tag="TU818_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL0923613.1"
                     /translation="MEKIGKMVEHLGQASRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERRKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPAAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQG"
     gene            27591..28901
                     /gene="der"
                     /locus_tag="TU818_000776"
     CDS             27591..28901
                     /gene="der"
                     /locus_tag="TU818_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL0923614.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDSFPVSSVHGIGTGDVLDAII
                     DNLPIEEPVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPELIKRISDSQSQRISSAILNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            29242..32334
                     /locus_tag="TU818_000777"
     CDS             29242..32334
                     /locus_tag="TU818_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0923615.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLHMNEDDTTKYRLLASGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKVEGFYQIGKNYFESLSILQFDQASQELIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKESSIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLMESPQLTVKREGGLLDISFDFSTVCQTDIEKALATLFSDRSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELAVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTETSKVLILAPSSLIYNWLDEFSKFAPQIDAAVSYGLKPARDALIQEGHQVTIT
                     SYSSFRQDLETYQANDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEARDVSRYIKPFVMRRKKEEVLPELPELIEMNY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDINRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRALLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKILELQENKRHLITTVLDGKQGLASMSVEEIKEILGLQP
                     "
     gene            32538..33131
                     /locus_tag="TU818_000778"
     CDS             32538..33131
                     /locus_tag="TU818_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923616.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKTPVVSKGSLHHSPVVDEDHSYAQKARRQAKQDVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAVKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            33175..34506
                     /locus_tag="TU818_000779"
     CDS             33175..34506
                     /locus_tag="TU818_000779"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL0923617.1"
                     /translation="MSKTYHFIGIKGSGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAAR
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            34554..35036
                     /locus_tag="TU818_000780"
     CDS             34554..35036
                     /locus_tag="TU818_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0923618.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAANVIKERAELISDTF
                     LVAVIANQFVGYIEGPVIAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASKHGGSVWYQMLWQP
                     "
     gene            35145..36719
                     /gene="mltG"
                     /locus_tag="TU818_000781"
     CDS             35145..36719
                     /gene="mltG"
                     /locus_tag="TU818_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL0923619.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASDIAAASQETTSTASTAHTSAIKLEET
                     AVATGDQALSPPEEPALSESLLKEEASVEGQTKKGGPVRRKTSKRQQTDRMAKKISTV
                     LISSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLI
                     KNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPE
                     GYTIKQIAKAIETNSRAKNRSKAKTPFHSKDFLNLVTSDAFIQEMAKKYPKLLGDLPS
                     KEVATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAI
                     DTTINSPYNVYINTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            36792..37274
                     /gene="greA"
                     /locus_tag="TU818_000782"
     CDS             36792..37274
                     /gene="greA"
                     /locus_tag="TU818_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL0923620.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(37515..38435)
                     /gene="yidC"
                     /locus_tag="TU818_000783"
     CDS             complement(37515..38435)
                     /gene="yidC"
                     /locus_tag="TU818_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL0923621.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQP
                     RKDVTAEKQALSTSKRTKLNRNAGKQKKRR"
     gene            complement(38518..38796)
                     /locus_tag="TU818_000784"
     CDS             complement(38518..38796)
                     /locus_tag="TU818_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL0923622.1"
                     /translation="MKKVRLIVSGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQASDPAKMTRFIQEIRKGPSKWAKVTYVDVNPSHFEDFHDFRISN"
BASE COUNT        11290 a         7214 c         9221 g        11350 t
ORIGIN      
        1 gtttgctttg aaagaggaaa cctgctttcc cttctttttc atttgatttt gaatgctatt
       61 tctggtgaaa tatggtaaaa taaaaagtac taattatttt ggagatgaaa tgagtgtcga
      121 tgattatagg ccgacctatg cggtagaggc tgtttatgat ttaagagcaa atgatttact
      181 gcgtcaaggt attacagctg tcttggtgga tttagataat accttaatcg cctgggataa
      241 tcctgatgga actccggagg ttcgtgcttg gttagatgag atgacgattg cagatattag
      301 tgtggtggtt gtgtcaaata acacgtattc acgtgtggag cgtgctgttt cgcggtttgg
      361 tgtggatttt attgctcgtg cgatgaagcc ttttgcctat ggtattaata aggctattga
      421 tcgttatggc tttgatcgtg atgaggttat tatggttggg gatcagctaa tgactgatat
      481 tagagctagt catcgggcag ggattaagtc tgtcttagtg aagcccttag taacatcaga
      541 tgcttggaac actaaggtta atagatggcg tgagcgtcgt gttttggcaa aattggaaga
      601 aaaatatgga aggctagtat atcaaaaagg gatttaatgg aagaattatt ttgtatcggc
      661 tgcggtatcc agattcaaac aacaagaaag caagaggctg gctttacacc tgctgctgct
      721 ttggtaaagg gaattgaagc tagggagatt tactgtcaac gctgctttag attacgtcac
      781 tacaacgaca ttacagatgt tcatattact gatgaagagt ttttgaggct gctccatgag
      841 gtgggagata gtgatgcctt ggtcgttaat gtgattgaca tttttgattt taatggctca
      901 gttattccag gcttatcacg ctttgttgct ggaaatgatg tgttattagt tgggaataaa
      961 aaggatattc ttccgaagtc tgttaaggac agcaaggtga cacagtggtt gacagaaaga
     1021 gctcatgagg agggcttgag acctcttgat gtcctgctga cgagtgcgca gaataaatat
     1081 gctattaaag agctgattga gcggatcgat caattgcgcc aagggcgaga tgtctatgtt
     1141 gttggggtga ctaatgttgg aaagtcgacc ttgattaatg ccattattca ggaaattact
     1201 ggggataagg atgtgattac aacgtcacgc tttcctggga ccactcttga taaaatcgaa
     1261 attcctttag atgatggtag ctttatcttt gatactcctg gtattatcca tcgtcaccag
     1321 atggctcact atttgtcagc taagaatttg aagtttatca gccctaagaa ggaaattaag
     1381 cctaaaacct accaattaaa tccggagcaa acgctttttt taggtggctt ggcgcgattt
     1441 gattttatta gtggtgaaag acaaggcttt acagcttatt ttgataatca attgctcctc
     1501 catcggacaa aattagaggg tgcagatgct ttttatgaca agcaggcagg gcaactgctg
     1561 actcctcctg ataaaaagga gcttgatgat tttcctaggt tggttcgtca tgaatttctg
     1621 ctggatcaaa aagtggacgt tgttttttct ggtcttggtt ggattcgtgt taatgctaat
     1681 aaggaaactg caactaaggt ggcggcttgg gctcctgatg gtgttgcagt agtcgttcgc
     1741 aaggcgatta tttaataaat aaaaagaaaa gtggaataaa aatgcttaca agtaaacaaa
     1801 gagccttttt aaaggctgag gcccatagtc ttaaaccgat tgttcagatt ggtaaaaatg
     1861 gcttgaatga tcagattaaa accagtattc gtcaagcctt ggacgctaga gagctgatca
     1921 aggttactct gttgcaaaat actgatgaaa cgattcatga ggtggcagag attttagaag
     1981 aggagattgg ctgtgatacg gttttaaaga ttggtcggat ccttattttg tttaaggtgt
     2041 cagctaaaaa agacaatatt ttgtttaagg tgtcagctaa aaaagacaat cgcaagctat
     2101 cagttaaggt caaatcgatc tagcgagagc ttttgctagg ctaagacgtt taggtctgct
     2161 gtgtcagtgc tgacaacatg agtaatggtg atattttgga gaggttatgg ctttagaact
     2221 tttgacgcct tttacgaggg tggaattaga aatggaaaaa aaagatagca atcgcaagca
     2281 ggttggtatc ttgggaggga attttaatcc tgttcataat gctcatttag tggtggctga
     2341 ccaggttcgt caacaattgg ggcttgatca ggtgcttttg atgcctgagt ttaagcctcc
     2401 gcatgttgac cacaaagaaa caattgatga aaaacatagg cttcgtatgc tggagctggc
     2461 tattcaggag acagaaggtc tagcgattga agagattgag cttacacgtc aaggggttag
     2521 ctatacctat gatacgatga agctgttaat tgagcaaaat cctgacgtgg attattattt
     2581 cattattggt gcggatatgg tagattattt gccaaagtgg caccgtattg atgagttgat
     2641 ccatatggtg cagtttgtcg gcgtgcaaag gcctaaatac aaggctggta cctcttatcc
     2701 ggttatctgg gtagatgttc ccttgctaga tatttcctca agcatgattc gtgactttat
     2761 ccaaagtgat cgtcagccta atcatttatt accaaaggct gttttagact atattcataa
     2821 agaaggcctg tatcaatgat gtatcaagat tatgttggct atagacgtga tgagctgtta
     2881 ggaaaaattg ctgagcagat gagcgataag cgctttaagc atgttcttgg cgtggaaagg
     2941 gctgctattc acttggcaga gcgttaccat tgtgatccga ttaaggctgg gttagcagct
     3001 ctactgcatg actatgccaa ggaatgtcct gatgagcttt ttataagctt aattgacaaa
     3061 tatcagctgg atcctgagct tcttaaatgg aacaataata tttggcatgg tatggttggc
     3121 atttataagc ttcaggaaga tttggggtta aaagacaaag gcattttgcg ggcaattgag
     3181 attcatactg ttggcgctgc tgagatgacg atattggata aaattctgta cgttgcagat
     3241 tatattgagg aaggtcgagt gtttcctttg gtggacgaag ctaggagaat agcagagctt
     3301 gatctagata aggcagttgc ctacgaaaca gctcatacag ttgcttattt ggcatcgaag
     3361 gctcagccga tttttccgca aaccattgat acttacaatg cctttgtgca ttatttacat
     3421 gaggaataaa atgagaaaag aagaactttt agaaattgtg attaaggctg ctgatgaaaa
     3481 gcgtgctgag gatatgctag ctcttgatct ggctggctta acaagcctaa cggactattt
     3541 tgttattgta acggcaacca atagtcgtca gttggaggcg attgctgaca atattcgtga
     3601 aagggttaag gaagcaagtg gtgatgctag tcatgttgaa ggaaacagtc agactggttg
     3661 ggtgctgctg gatttgaatg atgtggtcgt gcatatcttc tcagaagatg agcgttatca
     3721 ttataatctt gaaaagcttt ggcatgaggc tccagctgtg gagcttagcc actatttagg
     3781 ataaaaaagc agtcggctct gggctgtttt ttacaataag aaacagaaag gaagttggca
     3841 ttagaggcag gattgcctaa gaggtaagct cttgtagtac ttgctgtgag acgtgttgac
     3901 tgtatcaaat aatatgcaaa agaattatga taccttcgca tcagtttatg atgccattat
     3961 ggacgactca ctttatgata agtggacagc gttttcgctt cgtcatttac ctaaaaacaa
     4021 ggagcatcag aagcttttgg agctggcctg tgggactggt attcaatcgg ttcgatttgc
     4081 tcagtcaggc tttgaggtta ctggcttgga tcttagtcag gaaatgctag aggttgctaa
     4141 aaagcgagct caatcagcta agaagatcat tacctttgtg caaggtaata tgctggatct
     4201 gtcacaggtt ggatcgtttg atgtggtgac ctgctattcg gattcgattt gttatatgca
     4261 ggacgagatt gaggtgggtg atgtctttaa agaggtctat caggttttga atgatggcgg
     4321 tatttttatg tttgatgttc attctattta tcagatggat cacctttttc ctggttattc
     4381 ttaccatgaa aatgctgagg aatttgctat ggtttgggat acctacaagg ctgaggctcc
     4441 acattcagtg gtgcatgagc tgaccttttt tattcaggct gaggacggcc attttttacg
     4501 ctttgatgag gtacatgagg agcgtaccta tgatatcttg acctacgata ttttgctgga
     4561 gcaggctggc tttaagtctt tcaaggttta tgcagatttt gaggatcagg agccaacaaa
     4621 gacaagtaag cgctggtttt ttgttgcaca aaaatagctg tggctaagac aggtcagcga
     4681 gcggttttgt ggtttagtgg ctctgtattg agtctgtggc aggtcttgat gataatagga
     4741 atagatgcga aaggtaggac aatgttatga ctgtcactgg tattattgct gaatttaacc
     4801 cttttcatta tgggcatcag tacttactat cacaggcaaa ggggctaaaa attgttgcga
     4861 tgtcggggaa ttttgtgcag cgaggggagc cggcacttgt ggataagtgg gtacgcgcgc
     4921 aaatggcatt ggaaaatgga gctgaccttg tggttgagct cccttttctg gtttctgttc
     4981 aatctgcaga ttattttgct cagggagctg tggatatctt gatgagactt ggaattgata
     5041 cccttgcctt tgggactgag caattgcttg attaccagaa gctgtctagg ctatatagtg
     5101 aacaagcaga gcacatgact gcttatttgg ccaccttacc tgatcatcta tcttatccac
     5161 aaaaaacaca aagcatgtgg gaggcctttg caggccttag cgctactggt gataggccaa
     5221 accatctttt agcattatcc tatgtcaagg ccagcgcagg aaaaaagctg caattgcagc
     5281 cgattaagcg gctgggggca ggctttcatt cagaagccaa ggatcaatgc ttgtcatcgg
     5341 cgacagcaat tcgaaagcat atcgctgaca gagcctttgt ggaaaaatca tcacctaatg
     5401 cagctcttat tttgagggct cctcaggtga cttgggagca ttattttccc tttttaaaat
     5461 atcacattct gacagctcca gatttaacac agttttttca ggttaatgat gagctagcta
     5521 gtagaatcag cgcagctatt cggagtgtag cgacggtaga tgagctagta gaggcggttg
     5581 caaccaagca ctataccaag gcaagggtga ggcgtgtgtt gacctatatc ttggttaagg
     5641 ctgtggaagc cccattgcca gaaggcatac atgttttggg cttttcaaaa aaaggtcagg
     5701 ctcaccttaa aacaataaaa gcttctgtgc cgctaatcag tcgtattgga gctaagcctt
     5761 gggatcagtt gactcaacga gctgacactg tttatcagct gggacatacg gatatgccag
     5821 agcagacttg gggatgtgtg ccgataaggc cagaggcgat gaattgagcg ttactagaag
     5881 caaaccactg tctttgtatg acacgcttag aggaccagca agagcttcta agaagttcgg
     5941 gtaggcccta tagtcagttg gtaaaggtgt tattagagta gttcaggtga ctctttgctg
     6001 gtataaaggt cagatagact gcctttgctt gctaagctgt ttttcattgc tgataagaag
     6061 gatagttagc aagaactgtc agctcatgga agcttatcat ttaagatcaa aaaagttaag
     6121 tttgttcttg actctctccc tacgtgatag tctatacttg ttgttgaggt ggaaatagcc
     6181 atactagttg gtgctctttt gacctcacta aggaggaata ccatgaaaac cgtaaaagag
     6241 gttagtcaat tgacagggct tagtgtacgc accttgcatg agataggcct gctgcctcct
     6301 acaatggtgg gagaaaatgg ttatcgcttt tatgatgctg ctgccttgag acgtctacag
     6361 gacatcttac tgtttcgtga gctggcattt cctctaaaaa cgattaaaca attgctggac
     6421 agccctagct atgaccaaca agcagccctt gctgctcaga ttaagatgct agagctacgc
     6481 aaggctcatt tagaaaaggt tattgctcat gctaggactt tacaaaaagg agaagaaacc
     6541 atgacctttg acatttatag taagtcacag ctagaagcct ttcaactaga ggctaaggag
     6601 cgttggggag agacagaggc ctatatggct tatgaggcca aagtcaatca gcctagcgca
     6661 gagcagctta tcaaggatat gggggagatc ttttcaatct ttggtcgtat gctggatcag
     6721 cctgtagcag agctagcagt acagcagcag gtaaaggctc tgcaggatta cattagtcaa
     6781 cacttttacg attgctcaac tgagatctta tcagctcttg gttgtatgta tcttgaggat
     6841 gaccgcttta gagcagctat tgatcatatg ggtggtgcag gaacggcagc ctttgtcagc
     6901 cgagctatta gctattattg tcagcactaa gctgctaagt gcatatcact ggctgctatt
     6961 cctaatttac gaaccctttt gaaagtgcta taatgataga gttaaagcta atttaactct
     7021 gcttattcta aaaagagctt aatcaaaatt gtattttaga ggagaatcca atgggacgta
     7081 aatgggcaaa tattgttgca aaaaaaactg ctaaagacgg tgcaacatca aaggtttatg
     7141 ctaagtttgg tgttgaaatc tatgtggctg ctaagcaagg agagcctgat cctgagttga
     7201 atacagccct caagtttgtc attgatcggg caaagcaggc acaggtgcca aagcatgtta
     7261 ttgataaagc cattgataag gcaaagggta atactgatga gacctttgtt gagggacgct
     7321 atgagggctt tggaccaaat gggtcaatga ttatcgtaga caccttgacg tcaaatgtga
     7381 accgtacagc tgccaatgtt cgtgctgcct atggtaaaaa tggtggtaat atgggagcgg
     7441 ctggatcagt ttcttactta tttgataaaa agggggttat cgtttttaag ggcgatgacg
     7501 cagacagtat ttttgagttg ctcctagagg ctgatgttga tgttgatgat gtagaggcag
     7561 aagacggatc aattactgtt tatacagcac caacagatct gcataaggct attcttgctc
     7621 ttcgtgaatc aggtatatca gagtttcagg tgactgagct tgagatgatt cctcagtctg
     7681 aggtaactct tgagggggat gaccttgctg tttttgaaaa gctggttgat gcccttgaag
     7741 cagatgatga tgtgcaaaag gtctatcata atgtagctga tgtctaagcc ctaagactat
     7801 catgtaaaca gagccgagat ttctcggctc tgttcatttt cctataatcg agctctgtag
     7861 aggctgagta tgactatctg ccttttatgg taacagctga cgtagtagct gatcgtcaca
     7921 tggtgctgct ttagcagagt tcaatcatta gtatcttatg ataaaaaatg ataaactaat
     7981 cttatgaatc ataaaggagt agaggacaat gacaataaaa cgttatttag gtttagctgg
     8041 cttggccgta ctgtctgtgg gtatgctagc ggcatgtggc acaaaggaaa aatcagcttc
     8101 gagcacaaag gacacaccaa aagaggttat ctttgcgaca gttggaacaa ctgccccctt
     8161 ctcatttgaa aaggaaggac aattgacagg ctatgacatc gaagtggcta aggctgtgtt
     8221 taaagatgct gagaagtaca agcttcaatt taagaaaaca gaatggtcat ctatttttac
     8281 gggcttagac tctggaaaat atcaaatggg cggcaacaat atttcataca ctaaggaacg
     8341 ctcagtcaaa tatttgtttt cttatccaat tggtgcaact ccgtcagtgc tagttgtgcc
     8401 aaaggatagt gatatcaagt cttatgatga tattaagggt cattcaacac aggtggtgca
     8461 gggaacaacg actgctgctc agctaaaggc cttcaacgaa gagcatgctg ataatcctgt
     8521 tgagctaaag tttaccaacg aaaccatcac tcaaatgcta accaatctga atgagggcaa
     8581 ggctgatttt aagatttttg atgccccaac ggttaatgct atcattgata atcaaggctt
     8641 agatcacttg aaaacaattg agctggcaac aagcgagcag ccctttatct actttatttt
     8701 tagtcaagat caagaggagc tacaggcctt tgtcaataag cgcttagagg agctgacagc
     8761 tgatggcaca ctcagtaaaa ttgctaaaaa gtatctaggt ggcgattatg ttccagctaa
     8821 gcaggatttg aagcttccta cagcaaaatc ctaaattggc tgaaagacca acaacgatat
     8881 aagcgactat ttggcttaaa accaagctgt tagaaggctt gcttttaagc ctttttaaat
     8941 gcctttgttg cctactaggg cttttaaagt aacctagtgt ctagggcagc agctattaag
     9001 atctgttgcc ttatttcgag ggtggttttg aggtaaaagg tctgtagtaa gagccttgac
     9061 ttaattaatg cttgcttggc tagtctgtca gttggtttag gtttggtgtt ttgactagag
     9121 attatagcta atggctatac cttatcctaa aatttaccaa tttgaatgcg agagctattt
     9181 cgtataaaat aaactcattg aaaaaaagaa attgaggaac aaaatatgaa tattaaaaaa
     9241 gctgtcggct ttgttagcct tgctcttgct tcaatagctc tagtagcctg ctctggtaag
     9301 caggacgaca aaaatacctt gaccattggg gtaatgacta aaacggcatc tgatcaagcc
     9361 agatgggata agattgaaga gctgctgaaa aaggataaga tcactctaaa gtataaagag
     9421 ttcacagatt attctcagcc caacaaggca gttgctaatg gtgaggttga tatcaattca
     9481 ttccagcact ataacttttt ggataattgg aataaggaaa ataaggcaga tttgaaggct
     9541 attgctgaaa cctatatcag tccgattcat ctcttttcag ggactagtca agacggtaag
     9601 gctaaatacc agtcagtaga tgagcttcca gatggtgcgc aaattgcagt gccaaacgat
     9661 gcaacaaatg aaagccgtgc cctgtatgtg cttcaagcag ccggcttgat caagctcaat
     9721 gtgtcaggtg ataagctggc aaccattgca aatattacag aaaataagaa aaagctagat
     9781 attaaagaat tagatgcgag tcagacagca cgtgccttga cgtcagctga tgccgctatt
     9841 gttaataata gctatgccgt tcctgcgaaa attgatttta aaacctctct ttttaaggaa
     9901 aaggctgatg agaatgccaa gcaatggatt aatatcattg ctgctcaaaa ggattgggaa
     9961 aagtctgcta aggcagacgc gattaaggca ttaatcaagg cctaccatac agatgctgtg
    10021 aagaaggttg tggataaaac ctcaaatggt gttgacgtcc ctgtatggta agggataata
    10081 ggtaatatta gtaacaggag gattgaggcg tgtgaagcac gccctttctt atattagggg
    10141 gaaaacacat gacaaaaacg gatcagcagt acttaacaag gctttgggag gatcagctca
    10201 cacaggatta tcttgtgtcg ttggggcaat tgattgccag taggtctatt tttgctcaag
    10261 gtatcggctt agaagagaca gcagcctacc taaaggagct gtttgctcag gctggtgctg
    10321 aggctattgt tgataagact tatgcagctc cctttgtcct agcacgcttt aatagctcta
    10381 ggccagctgc taagacactg atattttaca atcattacga tacagtgcca gcagatagtg
    10441 atcaaaagtg gacgagtgat ccctttacct taacagagcg tgatggctat ttgtttgcgc
    10501 gcggcgttga tgatgacaag gggcatatca ttgcgagatt gacggctgtc gtcaggtatc
    10561 taaaggagca tgcagacctt ccgcttaata ttgtctttat gatggaggga gctgaggagt
    10621 cagcttcggt agatttagat cggtatctgg ctaaatacgc agaccagcta aagggagcag
    10681 agcttttgat ttgggagcag ggcattcgta atgagcatga tcagcttgaa ataactggcg
    10741 gcaataaggg gattttgacc tttgagatgt cagtagatag tgctcgttgt gatattcatt
    10801 ttaaatatgg tggtgttatc gagtcagcag cctggtattt gcttcaggcc ctatcaagcc
    10861 tgcggaacca tcgtggggaa ttgctggtgc ctggtattta tcaaaaagtc gttccgccaa
    10921 ctgagcgaga gctagattta gttgagacct atgcaattga gaatgctcaa gctctaaaaa
    10981 agctttacgg actggagctt cctatgttac aatcagagcg tcgtcaattg ttagcagctt
    11041 attactttca gccctccatt aacattcaag ggctgtggac tggctatcaa ggacaaggag
    11101 ttaagaccat cattccttca caggctactc ctaaaatgga ggttcgtttg gttcctggct
    11161 tagagcctga gtatgtcttt gatcagatta ggtcttattt gctcaataag ggctttgacc
    11221 agatcaagct gacctatact ttgggtgaga tgagctatcg gagtgatctt tcatcgtctg
    11281 ctattagtca gctgattgca gcagctcagc ctttttaccc taaggggcta tctcttttgc
    11341 cgacatcggc aggaacaggc cctatgcata ctgtttttga agccctgcag gttccgattg
    11401 ccgcttttgg cttagggcat tctaatagtt gtgatcatgc aggtgatgaa aacattgcta
    11461 ttgtagatta ttgtcggcat attgcattaa tagaggagtt aataacatct tatgagtgaa
    11521 ccaatgattc aattagatca tattgatatt acctttcacc aaaaaaaacg tgtgattgaa
    11581 gctgttaagg atgtaacgct tcatatcaac caaggggata tttatggcat tgttggctat
    11641 tctggtgctg gcaaatcaac cctagtgcgt gtgattaacc tgctgcagca gccaacaaag
    11701 ggaagcatta caattgatgg ggagctgacc tttgatcaag gcaaggttca gctgtctgct
    11761 aatagcctac gtgagaagcg tcgtgatatt ggcatgattt ttcagcattt caatcttatg
    11821 gcacaaaaaa cagctaagga aaatgttgcc tttgctctgc gccattctcg attgcctaag
    11881 gctgaaagag aaaggaaggt gactgagcta ttagaattag taggcttatc tgagcgtgca
    11941 gacaattatc cagcacagct gtctggtggt caaaagcaga gggttgctat tgcgcgtgcc
    12001 cttgccaatg accctaaaat attgatttct gacgaggcca cctcagcgct agatcctaaa
    12061 acgaccaagc agattctcgc tcttttgcag gaattaaacc gcaggctagg cttaacgatt
    12121 gtcatgatta cgcatgaaat gcagattgtc aaggatattt gtcatcgtgt ggctgttatg
    12181 cagcagggaa ccttgattga agaaggcagt gttttggata tcttctcaaa tccaagagag
    12241 cctttgacgc aggagtttat caagacagcg actgggattg atgaggcact tgagaaaatt
    12301 aaccagcagg atattgtcaa ggagctacca gctaatgcta ttttagctca gctcaagtat
    12361 gcagggacat cgactgacga gcctttactt aaccagattt atcgccagtt tgaggtgacc
    12421 gctaacattc tttatgggaa tattgaaatc ttagatcagg taccagttgg tgagatgatt
    12481 gttgtttttg aaggtgcagc agcaagtatt gaggcggcag aaaaagcctt gcatgaggct
    12541 ggcgtcgatg tcactatttt aaagagaggg gcttaaatgt tagaattgtt tcaggcttat
    12601 ttgccaaatg tttatgagct tggctggtct ggtgatgctg gctggggagt agccatttgg
    12661 aataccttgt acatgacgat cgttccattt attgtaggtg gagctattgg tttatttatt
    12721 ggtcttttgc tggtactgat ggggccagat ggggtgattg aaaatcgact ggtttgttgg
    12781 cttctagata agctcacgtc gatttttcgg gctattccct ttgttatatt aattgctatc
    12841 ctggcaagct ttacttatct gattatgggg acaaccttgg gtgcaaccgc agctctggtg
    12901 cctttgacct ttgcaacctt tccttttttt gcgcgtcagg tccaggttgt tttttcagag
    12961 cttgatagag gtgtgattga ggctgcacag gcttcaggag ctaccttctg ggatattgtc
    13021 agggtttatc tgagtgaggg cttaccagac ctgattcgtg tgtcaacagt gaccttgatt
    13081 tccttggttg gtgagacagc gatggcagga gctattggtg ctggagggct tggtaatgtc
    13141 gcgatttcct atggctataa ccgttttaac aatgatgtga cgtgggttgc cacccttatt
    13201 attctcttgc tgatctttgc gattcaattt attggagaca gcctgacaag gcattttagt
    13261 cacaaataat aaaactgctc agagctttat tagctccaag cagtttttta atgtcatgat
    13321 gctgtagggt gaagtccttt tgtcttgctg atgatgagac ctaagacaaa gcctaggatg
    13381 gaaaagctaa tccagcccat tgaaaattgg ccgagtggaa ccaacctttc aaagaaatag
    13441 gaaagaccat caggcaaggt aaagagcttg gttagctgtg agagggtagc tagggcgtca
    13501 tacaatgctg gaatgatggt aaggccaatc gtcgttctgt agacaagagg ggcattgcca
    13561 aatgactttt ggatcagaac aagaacaatc aaatcgacag tcagtgggta caagaggtac
    13621 aaaataggag atgaccaatt gataataact gacaagccac cgaagtagaa aaaggcagat
    13681 acaagggtaa atagagttgc ccaagcaaca tgtgataccc ttggcattag cttgtggaaa
    13741 tactctgcac ttgaggtgat aagaccggtt gaggtggtca gacaggctag gaaaatcaca
    13801 atcgcaagga aggcttgccc aatgctacct aggtaaaatc gtgaggcgtg gcttaaaatt
    13861 tgtcctccat tgacagcgct gttgtttagg gtaaaatgcc catcaacaaa agggaaaaga
    13921 gattgtgagg tcgcaccgat ccgtcccaca aaaatataaa caaaggctag cagcaaaatg
    13981 gcaatggccc cagagataag ggtgatttta gtgatttcct gatcggtttt agcgccaaat
    14041 tgcttggttg cttcaatgac taatatggca aaaaccaagg aagctaaagc atccatagtg
    14101 ccgtagcctt gaataagacc tgcaataaag ggaacgtcct taaaggcatt gttgatacct
    14161 gctccagcat taaaggcttc gccatagtct ccagctgggt gaacaaagga ggcaatgatt
    14221 aaaatagtaa tcacaaccaa tagcgtcggt gtcagaaatt taccaatgct ttctgctagc
    14281 ttgcttggtc taatagccaa aaagtaggat aagccaaaaa atagcacagc atagatggct
    14341 ttattgatga tgctatctcc taatatcggg gcaatcccaa cagagaagga ggtagcgcct
    14401 gttctaggaa tagcaaagaa aggaccaatg gacaaataca ggattgatga gtaaaggata
    14461 gcataccatt ttgaaattgg ccgagccagg ctttcaacat catcagagcc tgaccttgca
    14521 acagcaatga caccaagcaa gggtaaagac acaccagtca agcaaaagcc aataatggac
    14581 caagggatat tttgtcctga atagatgcca agaaaggccg gataaatgag atttgctgca
    14641 ccaaaaaaga gagcaaacag cataaagcca ataacgatat agacattttt ttctttcatt
    14701 gccttaataa gtctttcttt tgatataaat ttgaagattc caataattta attgaaaact
    14761 cttgaaaata ataacagttg ctattatacc taagtttctg aaagtcgtca acaattatca
    14821 gacgatagat caagctgaga cctaaaaaag cgctgagggg tatctggata aagcagctta
    14881 gcctttattt tacagctttt gagaggactt gctcacctgc tgaatctcta atcaagcctt
    14941 gctagaaaga gtggtccaag gcttggggag ctttgatgag agatttgctg tcttattgat
    15001 gaaagaatct gtcagctagc ttatgatggt ggggctgcag cggtgtataa catccttgct
    15061 tgatttgacg aataactaaa attatattat gataaaaaac atctaacttg agcgaggata
    15121 aataacatga aaagaattcg tgacttatgg gtcaggacca acctgattaa aaaaatagga
    15181 atcggggtcg ttataggact tcttttgggg attttattgc ctgatgtgac agcgattggc
    15241 attttggggc agctttttgt tggggcttta aaggcgatag ctcctctctt ggtttttgcc
    15301 ttggtggcac aagctatctc tcaccaaagg tcaggacagc aaaccaatat gaccttgatt
    15361 attgtgcttt atttgcttgg aacctttctg gcggccttgg ttgctgttat tgctaattac
    15421 ctatttcctc taaccttaac cttaaatact ccggttaata ctgagctttc accaccacaa
    15481 ggtattgttc aggtctttca gacgctttta ttaaagctag tggataatcc tattaatgct
    15541 ttagctactg ccaattatat tggtgtctta gcttgggcat tgatctttgg cttagccctc
    15601 aagtctgttc cttcagattt taagcatttg atcaaaacag cggcagatgt gacctcacaa
    15661 attgtcgttt ggattatcaa tgtcgcaccg attggcatta tgggcttggt cttttcaact
    15721 gtttctgaaa atggcattag cattttgtct gattatgctc ttttaattct ggtcttggtg
    15781 ggaacgatgc tctttgtagc gctagtggtt aaccctttgc ttgcctttgt cctgactcat
    15841 caaaatcctt atcctcttgt ttttagatgt ttaaaggatt ctggccttac agcctttttc
    15901 acaagaagct cggcagcaaa cattccagtc aatttgcagc tatgtgagga cttgggacta
    15961 agtcaggcga cctatttagt atctattccc ctaggtgcaa tgattaatat gggaggagca
    16021 gccatcacga tcaatgtttt gacacttgct gctgtcaata cctttggtat tcagattgat
    16081 tttctgactg ccctgctttt gagtgtggtt gcggctatct cagcctgtgg cgcttctggt
    16141 gttacaggag gctctctcct tcttattcca gtggcatgta gcctttttgg gatctcaagt
    16201 gatttggcta tgcaggttgt cggggttggc tttattgttg gtgtgattca ggattcctgt
    16261 gaaacagccc ttaattcatc aactgatgtc ctctttacag ccattgctga aaatgccttc
    16321 tggaagcaaa agaaggccta gccttataat acagcttatt agtaaaaaaa gaggctggga
    16381 caaaaagagc tgcactttag aaagtcttaa cctaatatac tttatgacct agtctcatgc
    16441 attaaaaaag cgaacaagtc tagttttcgg aatctctgaa aactggctcc atgtcaactg
    16501 tagtgggtga cttatagcta agcacgagag gagacgaagg ttgtcttctc ttttgtgatg
    16561 ttcaaagcga ggaagatgcg ttttttaggc tctataatct ccacagtggc cttacccact
    16621 acagaaatta tagagcctga aaactagact tgttcgttta ttttaggtca gacttttgtc
    16681 ccagacccgt tatgttattt gaggtagcct aggtagtcaa acttttcaaa ggtatgatcg
    16741 ttagcgatag caacaataat ggtgtcagcc tcaagtggtt caaagggctg aacattggtg
    16801 tctagggttt tgacctcttt ttgacgcatg ccaataatat taagctcgta ttttcgacga
    16861 acatcaagct ctgagagcga tttgccctcc cagctcttag gaatggtgaa ttcgatcatg
    16921 gaaatcccat gttctaggta gataatgctc tcaatgtgat ggcgtaagag atttgaggcc
    16981 actcgctttc cagagtctct ttcaggggtg ataaccttgg ttgctccaat gccatataag
    17041 acctcttcaa aaattttgtt tttagccttt gcaataatgg ttggaacccc taatttttta
    17101 cagtgcatga cagctagtac agaggactct agattgtttc ctgatgcgat gacaactgtg
    17161 tcacattgct caacccctac tgcgattaaa aaatccttat cagtaatatc gccaacagct
    17221 gccttggtcg ccaaatcagc aatttctttc acgtggcttt ctctaatatc aatggcaatg
    17281 acatcttggt catagttgct taattctctg gcaacggtgc ggccaaaaat ccccaggcca
    17341 agaacaccaa cagtttttcg ttttaacatg atttctcctt aacccactaa aatatcagta
    17401 gtggcatatt gaatggtttt ttctttacgt tgaattagac taatcaaaac agtaattggt
    17461 ccgacacgac caacaaacat cagcacaata atgattaggc gtcctgcact tgataagtgc
    17521 ggtgtgacgt ccattgatac cccaaccgtt gcaatagctg aaatggattc aaataaaagc
    17581 ggaatagggg cgatatctgg ctctacactt agcagtaaaa tgtagccaat catcaagacc
    17641 gcaaaaaaga aaatcaaaac agtcatggtt tgcttaatgg tcttgttggc gatgatacgg
    17701 ttacgaaagg ttacctcaga ttgaccggaa agctctgcct taaacaataa aaaggtgatg
    17761 gcagcagttg tgattttgat tcctccggca gtaccacctg gagctccacc gataaccatc
    17821 tgaatcatat aaagaatatt ggtaggagcc aaggtatcat tataagaaat agtcgcaaag
    17881 cctgcagttc tcatggttac cgtttggaaa aaggacacca tcagctgctg cggtagattg
    17941 tatctggcaa tagtattgag attgtccttt tccaaaaacc atgataaaaa ggtacctaaa
    18001 acaaggataa ctagggttgt ttgcagcact aagcgtgact gattagaaaa ctttttaaag
    18061 gtgatgccat agcagtgagg cctttcaaag aagtattttt taaaggcagt gcctaaatca
    18121 acccaaacag caaagccaag tccgccagaa ataattaaga aggtgataat agcattgatg
    18181 gtagggttta acacaaagtc ctttaagcta gatgatccta gattatcaaa gcctgcatta
    18241 caaaaggcag agacagccag aaagatactg ttaaagatac catttttcca gccgaaacga
    18301 gggataaagt cagtcatgat aaccaaggca gcaaaggcct ccagtgagaa ggtgacctta
    18361 taggcaaaaa agaggtattt ttttaagtcc ttactgtcac cacgattgag ggcggattgg
    18421 agcaaggttt gatcacttaa acgcattttg cgcttgagtg caaaggtgct gaccgcaatc
    18481 agagtgacca atccaagtcc gccaatttgc atgagcatca tggcaattgt ctgaccaatg
    18541 ccattgtaga catctgcaac aggaacgaca gaaagtccag ttacacagac cattgacacc
    18601 acgttgaaaa aatgatcgag gtaaaccgta ttaggaccat tgctgtagtg ggtaaaaggc
    18661 atggataaca agagactacc tatcaaaatg acaatcgcaa agctaaaggt tagccgctgg
    18721 gtcaccgata aggacttgaa aaatgagcgt ttcatgattc ctcctaataa tatctcatac
    18781 tatcatatca aaaatacatt aaaaaagcta agcagtaacc tagccttaga ctgaagcagc
    18841 cctgtttaca ataggccctt cctaacatgc tccaaaagac aatagctttt tttgacatgt
    18901 caggcttaag cttttagctc agagcttaaa agtgctgagt aagattttat aaagtcttaa
    18961 gggctttagt cattgttgcc acagtagaaa acagaatggc gagctcactg cctagcctat
    19021 gttttttctt gctaggcttc aaagaggctt gatgttttga agcgtcaaaa gtaatcttga
    19081 cagggttcta tatggctaat cgatatcact caaggctagc acttagcttt tgtggtttga
    19141 tcacatgatc attggctgtg gtcatagcgt cagctccctc ctactagcct ctaatggcta
    19201 ataggaggat caagggcaac aaaaaatgtt cagacagcct ttaatcaagg ctgcctgaag
    19261 cagcattcta tagcctctta caatggtttt ttattaggaa taccggcttt tcgagggtac
    19321 ttgtttggcg tttccttttt cttttcgaca agagtgatat agcggccatc tccattagga
    19381 agttggtagg gctggtgatc aagcacctta gcaaaaagta gctgaagtgc ctttttagct
    19441 tcttctaatt cttggtccgc tgcttgtgcc tttaaagcaa tcagttttcc cttgattttt
    19501 aaaaaaggaa tggtcaactc agacagaatc tgcatgcggg caacagctct agcagttacc
    19561 aaatcaaatt ggccacgaaa ttgcttgtct tgtccaaaat cctctgccct accatgatag
    19621 aaatgtactc cctctaatcc tagctcttta gcaaggagct gaagaaaatg tatgcgctta
    19681 ttgagagaat caataatggt aacatcaagc tttggaaaca taattttcat aggaatgctt
    19741 gggaagcctg ctccagcccc aatatctaac agcctgagag gctcatttgg aatatatccc
    19801 tgtaaaagcg gagcaacaga gtcataaaag tgcttgagat agacttcatt ttcttcagtg
    19861 atggctgtta agttgatctt acggttccaa tcaaccaaaa gcttaaaata agtgtcgaat
    19921 tgttcttttt gatgatttgt cagagcaaat cctgcttgct ccaggacaag gtaaaaggct
    19981 tggggtgtca tatatatcct ctgtttttaa ttaattgcta ctattttagc ataaaatagc
    20041 agaaaactgc tgaaaagtcc cttcaatact tgctattaaa ctgaaaattg ctataattga
    20101 gacacaaaga ttaaaggaga attacaatgc caatgttttt agtaatagta gcccttatcg
    20161 gtgtgctggt tgtttggctg atggttagct ataatggcct ggttaaagct cgtatgcata
    20221 caaaagaagc ttggagtcag attgacgtgc agctaaagcg tcgcaatgac ttgattccaa
    20281 accttgttga gacggtcaaa ggctatgcta atcatgaaga gaaaacctta gaaaagatta
    20341 ctagtcttag atcacgtgtg gctgatgcta ctacaccgca ggccacaatg gcagcctcca
    20401 atgaattgag caagcaggtc actagcctct ttgcagttgc agagagctat ccagacttaa
    20461 aggccaatag taatttccta aaattgcaag aggaattaac caatacagaa aataaaattt
    20521 cttattcgcg tcaattattt aatacaacaa catcgcatta taaccttaag ctagaaagct
    20581 ttccgagcaa tcttgtggct aaattgtttg gcttcaagcc aagtgagttt ttacaggttc
    20641 ctgaagctga aaaagaggtt ccaaaggtag actttaccgt ctagtctaat gcggctaatc
    20701 aaggtcagaa gaggacatca atgctttatc aacaaatttc acaaaataaa cgacgaactg
    20761 ttatcctgct ttttgccttt tttgtcttac tggtagtgat tggcgctgct gctgggtatt
    20821 tactggctga cagctaccag ctgggggctg cttttgctct gattattggt gctatttatg
    20881 cctttagcat gatttttcag tcaaccagcc tcgttatggg aatgaataag gctaaggaaa
    20941 tcacagtaaa cgatgctcct gatttctttc atattgttga ggatatggct ctggttgctc
    21001 agattccaat gccaagagta tttatcattg atgatccctc actaaacgcc tttgccacag
    21061 gctccagccc tcaaaatgca gctgttgcgg caaccactgg tctactaaag gtgatgaatc
    21121 gtgaggagtt agaagcagtg attgggcatg aagtcagcca tattcgtaat tatgatattc
    21181 ggatatccac tattgcagtt gctttagcta gtgctgtcac actgatttcc agcattgggg
    21241 ggcgtatgat gtggtatagc ggtggcagga gacgtgataa cgatcgcaac gataatggct
    21301 ttggcgctat tatgctgatt ttctcaatct tgtcactgat cttggctcct cttgcggcct
    21361 ctctggttca attagccatt tctcgtcaaa gagagtatct ggcagatgcc agctctgtcg
    21421 cgttaaccag aaatccagag ggcatgatta gggctctaca aaagctaagc aattcacagc
    21481 ctatgactca tccagtagat gatgctagcg cagccttata catcaatgag cctagaaaaa
    21541 aagaaaagct tagcgcttta tttagtaccc atccgccgat tgaagataga attgaacgct
    21601 tgaagcatat gtgagagctt gagactagct cagctctcat ttttactagc cataatgttc
    21661 agaaaacatc attaattaat tgttttgacc cggacatttt ttaagacttt tatggaaatt
    21721 tgggctattt tcataggggt tttatggtta aacatttgat tgttggcttg tcaatactta
    21781 tttgtatcca gacttaatgt taaaaaaagt tatgaatttg tcataaagct attgacaaat
    21841 tcttgatatc atagtaaaaa tagattagag ttttattagg aagtgtttta taggagaaag
    21901 catgttatct gtttcagata ttagaaagcg accggaaggc attcgctttg agagagagta
    21961 cgatgttaag gaagcgctgc ttatacgtga tccgcaggtt atagatatta ataacgtcag
    22021 agcttcgggg agagctcagt ttgatgacgg cttgtatcta ttagagtatc agctgggcta
    22081 tcagattacc ctgccctcga gccgttccat ggcgcctgtt gtcttagatg agatgcagac
    22141 ggttcaggag ctgtttatcg aggaagcaga tgtggcaagt aagcaggaaa tggttgatga
    22201 aaaccttgtc ttagtcttat cagaggatca gcttgacctt gaagagagta ttattgacaa
    22261 tattttgttg gcgattccct tgcaggtatt gacagaggct gaaaaggagt cacaaatctt
    22321 gccgacaggg gaggattggg cagtcttaac tgaggagcaa taccaggccc agcagaagga
    22381 aaaagcaaaa gacaacagtc cttttgcggg cttacagggt ctttttgatg agtaaaaata
    22441 aaaattaaag atgtctgtat tttttatttg aaaaaagaac agttgtctgg tatactttat
    22501 aaatatacgg catattagtc attttgatga ctaaatagca atacttgatt aatacaaaat
    22561 ggatgaatct tgtacatagc tgataagggg ctgtgataca ggaagtaagg attggtgtaa
    22621 tgacaaagaa aattttaatt atcgaagatg aaaagaatct tgcaagattt gtttcgcttg
    22681 agctacagca tgagggttac gaggtgaccg tcgaggttaa tggtcgtgag ggcttggaga
    22741 cagccctaga gaaggacttt gacttaatcc ttcttgattt gatgcttcct gagatggacg
    22801 gatttgaagt gacacgtcga ttgcaaacag aaaaaacgac ttacatcatg atgatgactg
    22861 cgcgtgactc tattatggac gttgtagctg gcttggatcg tggtgctgac gattacatcg
    22921 tgaagccatt tgccattgag gaattgctgg cgcgtattcg tgctatcttc cgtcgtcagg
    22981 acattgagtc agagaaaaag actcctagtc aaggcgttta ccgcgactta gtcttaaacc
    23041 ctcaaaaccg ctctgtcaat cgcggtgatg acgagatttc actgactaag cgtgaatatg
    23101 acctgcttaa tattttgatg acaaacatga atcgtgtcat gactcgtgag gagctcttgt
    23161 ctaacgtttg gaaatatgac gaggctgttg aaactaacgt tgttgatgtt tatattcgtt
    23221 accttcgtgg gaagatcgat atccctggga aagagtctta cattcaaact gttcgtggaa
    23281 tgggttatgt gattcgcgag aaataattga tggcaaagca gaaaaaatat aagaaaacgt
    23341 taccaaaacg tttatcgaat cttttgttcg ttctcttctt ttgcattttc tctgccttta
    23401 ccctactcgc ttatatttca acaaactact ttttgttgaa acgagaaaag caaactattt
    23461 ttcaggctgt taacattgtt agagttcgtc tctctgaggt ggactctaat tttacgttag
    23521 agaatttagc agaggttctc tataaaaatg acagaacgca tttaaagatt gatgacgcaa
    23581 atggtagtcg tattatcaga agtgaacgaa atatcaccaa cacgctcaat gccaatgagg
    23641 atatctatgt ctacaatgtt gataagcaaa tgatcttcac aacagatgac gaagaggcct
    23701 cgccaggctt aaatggaact attggtaagg taaccaagga ccacattgag gagcaataca
    23761 agggcttttc aatgactcag aaggtctact ctaataagac agggaagttt gtaggctatg
    23821 ttcaggtttt ccatgacttg gaaaactact acatgatcag agcacgcctc ttcttttggc
    23881 ttttggtggt tgagctcttt ggggttggtc tggcgtattt cattatctta attgtcacac
    23941 gcaacttctt gaagcctctg aacaatcttc atgatgtgat gcggacaatt tccaaaaatc
    24001 cagataatct gatgctgcgc tcgggtattt cctcgggtga tgaaattgag gaattgtccg
    24061 ttatttttga taaaatgctt gataagattg agacgcatac acgattgcaa tcaagattta
    24121 ttagtgacgt cagtcatgag ctgcgcacgc cagttgccat tatcaagggg catattggat
    24181 tattgcagcg ctggggcaag gacgatagtg ctattttaga tgaaagcctc actgcagctg
    24241 cgcaagaggt tgaccgaatg gctattatga tcaatgacat gcttgatatg atccgagtac
    24301 aggggtcctt tgaagggcat caaaatgata caactgtttt agagagctct attgagaccg
    24361 ttgttggtaa ttttagggtc ctgcgtgagg attttgattt tacctggtac tctgaaaatc
    24421 aaagaaccct agccaagatt tataaaaatc attttgagca ggctctgatg attttgatag
    24481 ataatgcggt caagtattct aggaaggaaa agaaaatcgt catagaatta gcggttaatg
    24541 ctagcaatga agctgtggtt aaggtcaaag acagaggtga ggggatctca gaagaggata
    24601 ttaagcatat ttttgagcgc ttctaccgca ccgataggtc cagaaatcga accagcaccc
    24661 aagcaggtct tgggattggc ttatccattt taaagcaaat tgttgatggc tatcatttac
    24721 atatggaggt tgagagtgag ctaaataaag ggtcggtctt tattttgcgg attcccttag
    24781 ctgatcatca aggctcatag ctgtatacct gcctgagtat ctagtagatg ctcaggcttt
    24841 tgactgttct aatgtgtggt gtgatgatga ggtgtttatc agggaaggag ggctcttgga
    24901 ggtaaacctg agtgcttgtc tattcttttg ttatccctaa aattatggta aaatagggta
    24961 ttagattaac gatagaattg gggtgtttgc gtgcgttgtc cgaaatgtaa ctataataag
    25021 tcaagtgttg ttgatagtag acaggcagaa gatggcaata cgattcgtcg ccgcagagaa
    25081 tgcgaaagct gtcacacgcg ctttacaacc tttgagcgct tagaagagct tccattacta
    25141 gtgatcaaaa aggacgggac tagggagcag ttttcaagag ataaaatctt aaatggtgtt
    25201 gttcaaagtg cccaaaagcg tccggtgtca agtactgaca ttgaaaatct catttctcgc
    25261 attgagcaga aggttcgtac agcctatgaa aatgaggtgt caagtactgt tattggcaat
    25321 ctggtgatgg aggaattagc agagcttgat gagattacct atgttcgttt tgctagtgtc
    25381 tataaaagct ttaaggattt agacgaaatc gaagagctct tacagcagat tactaatcgc
    25441 gttagaggaa aaaagaagag cagtgtagat gatgaagcct attgatacct tttcttatat
    25501 taagcataat caggttcaat acgattcaag cagcctgatt cagttgtatt ttcctattat
    25561 tggaaatgac gcagtggcag tttatcagta tttggttcac ttttttgatg atggctcagg
    25621 agcccacaaa tttagtgata ttttaaacca tctgcagttt ggaatgaagc gcctagagga
    25681 agccttggtg atgctgacag ctattgattt gctggtctta tatcagctgc cagatgctta
    25741 tttgataaaa ctacatcagc ccttgggcag ggaagccttt ttaaataacc caatttatcg
    25801 taggctttta gagcaaaaga ttggagatgt agcggttttg gagttgcaaa tggtgattcc
    25861 gaaccaggct agaaacatct caaagacctt ttcagatgtt tttggaatag actctcagga
    25921 gcttaagcag cctcagccat caaagataaa ttttgattta gatagctttc agcagctaat
    25981 gcggcgtgac ggtcttaggt ttgaggatca tcaaaaggac gttatcagtc tttacagtat
    26041 ttctgagcaa taccacctaa cctggtttga cacctatcag ctggctaagg caacagcagt
    26101 cggcggcagc attcgcccag agcgcatgct agtcaagaag cagcaagagg gcgctcaaaa
    26161 aacaagtgaa tcgttctcac cagctgagca ggttgttctt agagagtcta agcaggacac
    26221 gcctcttgtc tttttagaga agatcaaaaa agctaggcga gctagagtca caaaggacga
    26281 aaaggaattg ttgctgactc tagcccgcat gaatttcttg gacgaggtca tcaatattat
    26341 ggtattatat accttcaata agaccaagtc agctaatctt cacaagactt atctgatgaa
    26401 aatggcaaat gattttgctt accagcgggt tttaacagcg gaaactgcta ttatcaagac
    26461 acgcgccttt ggtgagcgta agcagcaggc aaagtcacag cagtccaatg tgcctaagtg
    26521 gagcaatccg gattatcaag aaaaaacaag tcaggaagaa caggcaaagc tagagcagtt
    26581 taagcaggct gccttaaaaa ggctggagaa cctaggaaag agtggtgact agatggaaaa
    26641 gatcgggaaa atggtagagc atttgggaca ggctagtcgt gtagctagtg ctgagctgat
    26701 tgaggctata cttgctgatc aggaggtggc tgagtttatc aaggctcacc agctatctca
    26761 ggcagaaata aagctgagtt tatcaaagtt caaccagttt ttagttgagc gccggaaata
    26821 ccagacaggt gatgagacct atattgctaa gggctatcag cccattttgg tcatgaacga
    26881 gggctatgca gatgtgtctt acctagagac aagagagctt gttgaagccc aaaggcaggc
    26941 agctattgca gatcggattc atttggttag tctgccaaga tcttatcgta gggtttcttt
    27001 gtcagctgtt gatgttaaca atgccagtcg tatgcaggtg ttttcagagc ttttggattt
    27061 tgttgagcag tatccagcgg cagagcaaaa gggtctctac ctttatggcg atatgggggt
    27121 cgggaaatcc tatctgatgg ctgctatggc acatgaattg tctgaaaaaa agggtgtatc
    27181 aacaactctt cttcattttc ctagctttac gattgatgtt aaaaatgcca tttcaaatgg
    27241 ctctgtcaaa gaagagattg atgccatcaa gcatgtccct gttttaattt tagatgatat
    27301 tggtgcagag caggcgacct catgggtgcg tgatgaggtg ctacaggtta ttttgcagca
    27361 tcgtatgcta gaggatttgc caaccttttt cacctctaat tacagctttg cagatttgga
    27421 gagaaaatgg gcaaagatca aaggaaatga tgagacctgg caggccaagc gtgttatgga
    27481 gcgtgtgcgt tatttagcac gtgaatgcca tttagaaggg gttaatcgcc gccagggcta
    27541 gctaaacgct agctcaagcg atggataatg agataaagaa aaggagaatc atggttttac
    27601 ctacagttgc cattgttgga cgtcctaatg ttggaaagtc cacgttattt aaccgaattg
    27661 caggagagcg tatttctata gttgaagacg tcgaaggggt tactcgcgac cgcatttaca
    27721 cgactggtga gtggcttaac cgccaatttt cattgattga cacaggtggt attgatgacg
    27781 ttgatgctcc ctttatggag caaatcaagc atcaggctca tattgcgatg gacgaggcag
    27841 atgttattgt ctttgtggtt tctggtaaag agggcgttac tgatgcagac gaatatgtct
    27901 ctaagctctt gtatcgtacc aacaagccag tgattttggt tgtcaacaag gtggacaatc
    27961 cagagatgcg aaacgatatt tatgattttt attctcttgg cttaggagat tccttcccgg
    28021 tatcatcagt tcatggtatt ggtacgggtg atgttttaga tgctatcatt gataacctgc
    28081 cgatagaaga gccagtagaa aacgacgatg tgattcgctt tagcctaatt ggacgtccaa
    28141 atgttggaaa atcaagcctc attaatgcga tcctaggaga agagcgtgtc attgccagtc
    28201 ctgttgctgg tacgactcgt gatgcgattg atacaagctt taccgatgaa tccggtcaag
    28261 cctataccat gattgatacc gcaggaatgc gtaagtccgg caaggtctat gaaaatactg
    28321 aaaaatactc agtgatgcgt gccatgcgtg ccattgaccg atcagatatt gtgttaatgg
    28381 ttattaatgc cgaggagggc attcgtgact atgataagcg gattgcaggc tttgcgcatg
    28441 aggcaggtaa gggcatgatt atcgttgtta ataagtggga caccatcgaa aaggataatc
    28501 atacagtagc taggtgggag gctgatattc gtgatcaatt tcaatttttg acctacgccc
    28561 ctattatctt tgtttctgcc gttacaaagc agcgcttaaa caggcttcct gagttgatta
    28621 agcgtatcag tgatagtcaa agccagcgga tctcgtcagc tattttaaac gatgtgatta
    28681 tggatgctat tgcgatcaac ccaaccccaa cggataaggg acggcgtcta aagattttct
    28741 atgctacaca ggtttctgtg aagccgccaa cctttgttgt ttttgtgaat gaagaagagc
    28801 tgatgcactt ctcttatctg cgctttctag aaaaccagat tcgtgctgct ttcacctttg
    28861 aagggacacc aatcaagctg attgcgcgca atcgcaaata agccctttta ttactcttgt
    28921 tagtattgga agcagcgagt gctgttgatg tgcggtgtct agaccttgtg tgtcaggact
    28981 tttgaccgac caataagcct taccagaaat gagaggctgc tatccaaata gagcttacca
    29041 gcaagcaagg cgtgccaagc attgatgtca catgataatc attagcccta ggctagtgat
    29101 tttttagtgc tttaaagcct atcagaacag ctatatacag ctactcaaat atgttttaat
    29161 agcctttaag agagattttt gcaggaaatc taagctgaag tttgttataa tcaaaggata
    29221 agcaaaaagg tgggagcaga tatggctaga ttaattccgg ggcggattcg caatcaaggc
    29281 atcgagcttt atgagcaagg cttggtgaaa atcatagatg acaggactga ccttcttcga
    29341 gcagaggtgg atacttatca ggttcaatat ggtatcaatg atgaggatat taggtgtcag
    29401 tgtgattatt ttgagcgaaa gcagtattgc cagcacattg cggctctaga atattttctg
    29461 aaaaataatc agaagggcaa gtcgctctca gagcagctta acaaccagct ggaaagtaag
    29521 gaggaaacta aaaagctgac ctcctttggt agtctttttt tggacagttt gcacatgaac
    29581 gaggacgaca cgaccaaata taggctttta gcttctggtg ctaaaagtcc tttctcatct
    29641 gattactggt ggagccttaa gataaatcgc ttgcccggag agaaggctta tgttatccgc
    29701 gatatcaagg cctttattca tttggtcaaa gttgagggct tttaccagat tggaaagaat
    29761 tactttgagt ctctttccat attgcagttt gatcaggcta gtcaggagct gattcgtttt
    29821 ctttggcgtt tatcaacgca ttcagataag ttagattacg aatggctatt tcctaaccac
    29881 gctcgtcatc ttcggttacc ggcaggcttt tttgaggagg gcattgacct gctgacgggg
    29941 ctttacgagt tttcatttga gacctcctct caaacctatt ctcatcttta tgttcgacct
    30001 ctggaggcag aggctggtct ctttcagttt acagttgatg ttcatcgcag ctctattgag
    30061 ctttacatta aggaaaaaaa tatagagtat tttttcaata atgaatacct gctatacatg
    30121 aacacctttt accacctgag cctgaagcag caaaaaatgg ttcaagctat tcgcagcctg
    30181 cctattgagg ccgatttggc caagcacatt cattttgatc ttgatgatca ggctaagctg
    30241 gcagctagct tgctggaatt tcgagagctt ggtcaggtga aggctcctaa aagctttgat
    30301 attagagatt tccaagtgac ttttgtcttt gatattactg aaaaaggtga gttgacctct
    30361 cagctgattt ttgactatgg gagcattcag atcagtgata aggcaagctt agaccagctc
    30421 ccctttgcta gccattataa aaaagaaagc agtatttatc gtgccttgaa gcgctttggg
    30481 ctttctccgc agttttttgc taagaaagcc ttgactgacc ccaaggactg gtatcgcttt
    30541 tttacagaag ctgttcctta ttttgaaagt ctaggtaggg ttcagctttc ctctaagctc
    30601 caagatcagc gcttaatgga aagccctcag cttacagtca aacgtgaggg aggtctttta
    30661 gatatttcct ttgatttttc aacggtttgt cagactgata ttgaaaaggc tttggccact
    30721 ttgtttagtg atcgctctta ttttgtcaat cagtcaggca agctggtcgt ttttgatgaa
    30781 gagacacaaa aaatcagccg tagcttacag gaactaagag ctaagcagct ggcaaatggt
    30841 cacctccagc tagaaggaat agctgccacc cagctgtctc atctattttc ggatctgtct
    30901 tctgttcatt tttctgagga gctagagacc ctaatcaagg acctgcagca cccggatcgc
    30961 tttgagctgg gagagctggc cgttaaggcc aaggtgagag attatcagct gcagggcatc
    31021 aaatggctct ctgtgcttga taagtatggc tttggtggta tcttggcaga tgatatgggc
    31081 ttgggcaaga cactgcaaat cattgccttt ttatcaagca ggctaaccga gacctccaag
    31141 gtgcttatct tggcaccctc tagcttgatt tacaattggt tagatgagtt tagtaaattt
    31201 gcccctcaga tagatgctgc tgtatcctac gggctaaagc cggcacgaga tgctcttatt
    31261 caagaaggac atcaggtgac gattaccagc tattcttcct ttaggcaaga tttagaaacc
    31321 tatcaggcaa atgattatga ttatttaatc ttagatgagg cgcagatgat taaaaatgcc
    31381 cagaccaaga ttgctcagag cctgcgtgcc tttgacgtga agaattgctt tgctttatct
    31441 ggtacgccga ttgaaaataa gctgcttgaa atctggtcca tttttcaaat tgttctgcca
    31501 ggcctgctgc catctaaaaa agcctttttg aaaatggagg ccagagacgt ttctcgctat
    31561 attaagccct ttgtcatgcg acgcaaaaaa gaggaggtct tgccagagct accagaatta
    31621 atcgagatga attattacaa tgagatgtcc gatggtcaaa aagcgattta tctggcacag
    31681 ctaaggcaga tgcaggagcg gctgtctgct gcaactgatg atgatattaa tcgcagtaag
    31741 ctggaaatcc tgtctggtat cacacgtcta aggcaaatct gtgatactcc tagcctgttt
    31801 atggattatc aaggaggaag cggtaagcta gacaatctaa gaaccttgct gctgcaaatt
    31861 aaagaaaacg gtcatagggc tttgctgttt tcacaattta agggcatgct ggctcttgtc
    31921 aagcaggaaa tggatcagct tggcttatca tcttatacca taacaggctc aacaccggcc
    31981 aatgaccgtc aagaaatgac acgtgccttc aataatggct caaaggacgc ctttttgatt
    32041 tccttaaagg ccggtggtgt tggactcaat ttaacaggtg ctgatactgt tattttgatt
    32101 gatctatggt ggaacccagc tgtagaaatg caggccatta gtcgtgctca tcgtattggt
    32161 caggaggaca atgtagaggt ttaccggttg attacccgcg gaacaattga ggaaaaaata
    32221 ctggagcttc aggaaaataa gcgtcatctg attaccactg ttttagatgg caaacaaggc
    32281 ctagcaagca tgtctgtcga ggagatcaaa gaaatccttg gtcttcagcc ctagcatgta
    32341 tggcttttag cacacgctct taagcctatc agctaaaggc tagtgtctgt tctctataac
    32401 aaataaggca agagaataga ggtgatgagc tagtcacatc atttttgctt tgctgccttt
    32461 ctttttagga attactttga aaaataggat tatttagttt ataataggga atgctatagg
    32521 aaggagagtg agatagaatg acaaagcatg cgtttcctct ggttgcagat ggtgagccta
    32581 ttattgagtc agctaggcag atggctttat atgaaaacga agatttgatc acaaatattg
    32641 ctggcagcta tcaagataaa cattacgacg acatcataag agaccatcaa tttgctgaga
    32701 agactcctgt cgtctctaaa ggatcccttc atcattctcc agttgtcgat gaagatcata
    32761 gctacgctca aaaggccaga aggcaagcaa agcaggatgt caaagaaaaa agacaggctt
    32821 atattgctaa aaatatggct tatagcccaa agcaggcaag caagaaaggt caaagtgggg
    32881 ccttctcttc taaaaaacca gcgacagaat tgagccgttt tacagagaaa ttaaaccaag
    32941 agtcttatat tttagctgag cttcctcgtc aatataagga gccgcaaaat accagccaag
    33001 cagctgtcaa aaaaaataat tatgactttt tgaagcgcag ccaaatctac aatcatcaag
    33061 aagacagaga tcatcgtgaa aagaccattg ctcaagagct aaacctgagt cgctttgaag
    33121 atattaagta agctttatac agccttatgt ctgtcaacat taaaaggagt taacatgtca
    33181 aaaacctatc attttatcgg aattaaagga tctggaatga gtgccttagc cctgctgctc
    33241 catcaaatgg ggcataaggt tcaaggcagt gatgtggaga agtattattt cacacaaaga
    33301 ggcctagagc aagcaggcat taccattttg ccctttagcg aagataatat ttctccggat
    33361 atggagctga tagcaggtaa tgcttttcgt gaggacaaca atagcgaggt tgcttatgcg
    33421 atgcgtcatc agctgccctt taaacgctac catgagtttt taggtgagtt tatgaagcag
    33481 tttactagtc ttggtgtagc cggtgctcat gggaaaacct ctaccacagg cttgttgtca
    33541 catgtgctca agcacatgac ggctacttct tatttgattg gtgatggtac tgggcatggg
    33601 gctgccgatg ctcgttattt tgtgtttgaa tcagatgagt acgagcgtca ctttatgcct
    33661 tatcacccgg aatattctat tatcactaat attgattttg atcaccctga ttattttaca
    33721 ggccttgatg atgtgttcaa tgcctttaat gactatgcta agcaggtgaa aaaggctctt
    33781 tttgtttacg gtgaagatga ggaattaaga aagattagct ctcctgcacc gatttactat
    33841 tatggctttg aggacactga tgatttcgta gcctttgata tcacacgcac gacaaatggc
    33901 tcagacttta aggtaaagca caagggtcat gctattggtc agtttcatgt tccagcctat
    33961 gggcgtcaca atattttaaa tgctactgcg gtgattgcta atttatttat tgcaggcttt
    34021 gatatgaagc ttgttgcaga gcatctgaag agcttttcag gggtgaagcg tcgttttact
    34081 gaaaaggtga tcaatgacac tattattatt gatgactttg ctcatcaccc aacagaaatc
    34141 attgcaacgc ttgatgctgc taggcaaaaa taccctaata aggaaatcat cgctattttt
    34201 cagccacaca cctttacaag gaccattgct ttgctagatg actttgccca tgccctaaat
    34261 gaggctgaca gtgtttatct agcgcctatc tacggctcag cgcgtgaggt tgataagggt
    34321 gatgtcaagg tggaggatct agcggctagg gttgagcgcc cagccaaggt catctcagtt
    34381 gacaatgtat caccgctgct ggatcatgat aatgcagtct atgtttttat gggagcaggt
    34441 gatattcagt tgtatgaacg ctcgtttgaa gagctgctgg ctaacttaac taaaaataat
    34501 caatgattaa gcgacctgcc ttaggcaggt tttctcgtcg taaaggagga cctatgctaa
    34561 ttagacatgt gaatcagact gactgggaga ttattgctga tatcgaacag gccaattttt
    34621 ctccccaaga ggctgtagca gccaatgtga taaaagagcg tgcagagctt atttcggata
    34681 cctttcttgt ggctgttatc gccaatcagt ttgtcggcta tatcgaagga cctgtcattg
    34741 ctgagccaag gcttgaggat cacctatttc atggtgtgac caagaatcca gcaagaggtg
    34801 gctatatagc cattaccagt ctttctgttg ctcctggata ccaaaagcag gggattggca
    34861 cagctctctt agctgcaatg aaggatttag cagttgcaca ggatcggctg ggtatcatac
    34921 ttacctgtca tgactatttg attccttact atgagatgaa tggttttcaa gatcaaggcc
    34981 tgtcagcttc aaagcatggt ggctctgttt ggtatcaaat gctatggcag ccataggaag
    35041 gctattaaag cttagcatgt attaagaatt agtaacaaaa gggggatttt attgcattta
    35101 tagtgcaatt aggatataat ggcggttgat taagtttagg aggaatggct ttgactgatt
    35161 ttaaagatga tgagcaaaga cgtcagcagc aaaaaagctt caaagaaaag attctagccg
    35221 aattagaaaa agcaaatcag attagaaaag aaaaagaaga agagcttttt aaaaaggatc
    35281 tagaggttca agaggctgct agaagaacag ctcagcttta tgcagaatat aaaagacaag
    35341 aagcactaag caataacccc aaacaagcgt ctgatatagc agctgcgtcg caagagacga
    35401 cctcaacggc ttcaacagcc cacacctctg cgattaagct agaagagaca gcagtagcta
    35461 ctggggatca agcattgtcg ccaccagagg agcctgcatt gagtgaaagc ctgcttaagg
    35521 aagaggcaag tgtcgaaggt cagactaaga agggtggtcc agtgagaaga aaaacaagta
    35581 agcgccagca gacagatcga atggccaaaa aaatttcgac agtactgata tcgtcgattg
    35641 tcgctattat tgtggtgatt ggcctcgcag ggacagccta tgtgtatagt gcccttaacc
    35701 ctgttgacaa aaatagcgat gactttgttc aggttgaaat cccagccggc tcaggcaata
    35761 agcttattgg gcagatcctt gaaaaagagg ggctgatcaa aaatagtacc gtctttagct
    35821 tttacactaa gtttaaaaat ttcactaatt ttcaaagtgg ctactacaac ctacaaaaga
    35881 gcatgagcct agaagacatt gcccaggcct tacaagaggg tggcacagca gagcctacaa
    35941 agccagtact aggaaaaatt ttaattccag agggctatac cattaagcaa attgctaagg
    36001 ccatagaaac taatagtagg gcaaagaatc gtagcaaggc taaaacacca tttcactcaa
    36061 aggatttctt gaatttggtg acaagtgatg cctttattca agagatggct aaaaaatatc
    36121 cgaaattgct aggagatctt ccaagcaagg aagtagctac ttatcagcta gaaggctacc
    36181 ttttccctgc gacctataat tattataagg aaacaacact aaaagacctt gcagaggaaa
    36241 tgattgcagc ggcaaatgca aacctagcgc cttattatga ggcgattgca gctagtggca
    36301 agacagttaa tgaggtgctg actttggcct ccttagttga aaaggaaggc tctactgatg
    36361 acgatcggcg tcaaattgcc agcgtatttt acaatcgctt aaataatggc atggccttac
    36421 agtctaacat tgctatattg tatgcaatgg gtaaattggg agaaaagaca accttagcag
    36481 aggacgctgc tattgacaca accattaatt ctccttataa tgtttatatc aatactggct
    36541 taatgcctgg tccagttgat agtccagggc ttgcagctat tgaggcgact atcaatccag
    36601 cggcaacaga ttacgtttat tttgtagccg atgtgcgtac tggtgaggtt tattatgcaa
    36661 aaacatttga agagcactct gcaaatgttg aaaaatatgt taacagtcaa attcagtaag
    36721 gacaaacatg gtgctttagc atcatgtttg tgtttctgat tcgtcaaaag aaaaaggaaa
    36781 agagaaagat aatggcagaa aagacttatc caatgacagc agcagaaaaa gaacagcttg
    36841 aaaaggaatt agaagagcta aaattagttc gtcgtccaga ggttgttgag cgcataaaaa
    36901 tcgctcgttc gtatggagac ctttctgaaa actctgaata cgatgctgct aaagatgagc
    36961 aggcttttgt tgagggacaa atctcaacct tggagacaaa gattcgctat gctgagatta
    37021 ttgatagcga tgctgttgcc aaggacgagg tggcgattgg taagacagtt gttgtccagg
    37081 aggttggcac acaaacaaca gacacttatc atattgtcgg tgcggcagga gcagatattt
    37141 tttctggaaa gatttcaaac gagagtccaa ttgcacaggc cttgattggt aagaaaacag
    37201 gagataaggt taagattgag tctccagcag ctacctatga ggttactatc atcagcgttg
    37261 acaaaacaca ataagactta tctgactatc agtgcagtgt cctgatagtc tttttagtgg
    37321 cttgcttttt aatatcagtt gttgtggtct attaaaaaga gctgcacttt agaaagtttt
    37381 aactaagata ctttatgacc tagtctcata cattaaaaaa gcgaacaggt ctaattttcg
    37441 gaatccctga aaattagacc tgttcgtttg ttttatcttg agtcagactt ttgtcacaga
    37501 ctcttttagc tatcttagcg acgctttttt tgtttaccgg cgtttcggtt taacttagtc
    37561 ctcttgcttg tgctaagggc ttgcttttca gctgtaacgt ccttgcgtgg ctggtgagat
    37621 ttataggcct taggagggtt ctttgcgaac tcctctgcaa tttgcttgcg gagccttggt
    37681 tttaaaaggt aggttgtgat caattgctga atgatactaa agaaaccacc aactagccaa
    37741 tacaagccta atccggcagg caggtaaaac gacatgacaa tcatcataat tggcatggtg
    37801 tacagcatgg ctttcatttg ttcacgttgc tcctcaggga ctgccatcat tgacagccag
    37861 gattgaacga agtataaagc cgcaattaca gctgtaagca agacgctgcg atgccccagg
    37921 tcaatgccca taaaggtact tgttgagact cccttggtaa attggaccgc aacatacatg
    37981 gcagaaaaga aaggcatttg aatcagcagt ggcaaacagc ctataccgcc tagcgggttg
    38041 actccatttt cacgctgggc cgccattaat tctgtttggg ctgccatttt ttcttcagtg
    38101 cttgtagcgt ttttgatgcg ttgattaatt ggctcaaaaa aaggctttag gtaggccatt
    38161 ttttctgatt ggtagcttgc cttccatgat tggtagagcc caagtggtag gataatcgtt
    38221 ctaacaataa tagttacaac aatgatggca agaccatagc ctagggcggt gctgttagca
    38281 aagtaatcaa tgagaaagga aacgggcttt ccaaggtaat cccaaatgat gccctccggg
    38341 tgccccttgg cgtctctgcc gacacaccct gtcaatgtca gtaggaccga taaggcaagt
    38401 cctgagaaaa gtatgcgatt cgttttgagt ttcaatgtgt ttgtccttta atttttaata
    38461 tacctaacca ttttactgtt tttttgagaa attaacaata gttctacagt aggattttta
    38521 attgctgatc ctaaaatcat ggaaatcctc aaagtgagat ggattaacat caacataggt
    38581 cacctttgcc catttagaag gtccttttct gatttcctgg ataaagcgcg tcatctttgc
    38641 agggtcacta gcctgtgcta aaatctcaac agtcccatca ctattgttcc acacgcggcc
    38701 gtaaatatca ccaatttcca aagctagtgc gtaggttgaa tagcgaaagc caacaccctg
    38761 caccctgcct gaaacgatta gtctgacctt tttcataagt cacctctttt ctttttatta
    38821 tagcatagat agcttataaa tactaaaagt tgtcatggag caggcagcca aaggataggc
    38881 aaagactgca agtgggctat ctgctgaggt aaacaatagg tcttagtgca gcaaggctat
    38941 gtttatggtt agctctcctt cttgtcttct aaaaaggaaa gctaatgggc ttacgacacc
    39001 tgataagggg agaaagctcc ttttaggctg atagccttct gatggttttt atgcaaaaga
    39061 gtgaacaatt ttgtg
//
LOCUS       DARYMD010000017        39068 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYMD010000017 DARYMD010000000
VERSION     DARYMD010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39068
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(93..464)
                     /locus_tag="TU818_000785"
     CDS             complement(93..464)
                     /locus_tag="TU818_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923623.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLVLSFDSSWLYWLTII
                     GLSSIIVSYLVPRFKWVVTQS"
     gene            683..1321
                     /locus_tag="TU818_000786"
     CDS             683..1321
                     /locus_tag="TU818_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL0923624.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPEDFI
                     GGNLQQIWDKVLAGQANADEARDIAVAYEAYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKVAQALGLAKA
                     EFVVVEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADKRIDSLRQLCELLR"
     gene            1517..2053
                     /locus_tag="TU818_000787"
     CDS             1517..2053
                     /locus_tag="TU818_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0923625.1"
                     /translation="MLSLLIGGLMAVKLLTERLIIQELNETYFEPYHKAFTEEITAFQ
                     WPDPFKDIAAAKETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKNKYRYFNYEVDVRNTGNIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            2916..3320
                     /locus_tag="TU818_000788"
     CDS             2916..3320
                     /locus_tag="TU818_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL0923626.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTRVSLTMFVTSKKRSSD"
     gene            complement(3376..4860)
                     /locus_tag="TU818_000789"
     CDS             complement(3376..4860)
                     /locus_tag="TU818_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL0923627.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKILEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASRQEIIRRYYQTLVDFKAERVTEAAVKKLELLMND
                     IGVTPKDRQVTLIARQKAEITGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKE
                     LGNLKGSEAHSTVILTNEDKHVLRQLGINVTFDPVYQHHKLYRS"
     gene            5219..6442
                     /locus_tag="TU818_000790"
     CDS             5219..6442
                     /locus_tag="TU818_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0923628.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAEKMGRVSSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMVAIDDDKIIDNHVNVSEEASQPVKISELFKTPALT
                     GQTLALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTIVGMCLGMLTFG
                     HLLDTFGPRLVYSIFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGKILDVSSVSMVMLFLALLYLVSFVALW
                     TIKNLKAERYQALTK"
     gene            complement(6532..6891)
                     /locus_tag="TU818_000791"
     CDS             complement(6532..6891)
                     /locus_tag="TU818_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL0923629.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            7056..7775
                     /locus_tag="TU818_000792"
     CDS             7056..7775
                     /locus_tag="TU818_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL0923630.1"
                     /translation="MRLDKFLVDAGLGSRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAHLDILEINESLKTSLVKITIEEGKFHQVKRMVAACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELEAGWVSC"
     gene            complement(7820..8647)
                     /locus_tag="TU818_000793"
     CDS             complement(7820..8647)
                     /locus_tag="TU818_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL0923631.1"
                     /translation="MVLPHFDDYLEKYANLLIKKGVNIQKGHTLLISIAVEQHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRAATQANKVSWNLAAAAGPEWAAMVFP
                     NLTSEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKARLLNDYQFDSLHYRAP
                     GTDLRLGMPEQHIWEAAGLNRSTAHADFMIGSEQMDIDGITKDGEVIPIFRGGEWAI"
     gene            8908..9036
                     /locus_tag="TU818_000794"
     CDS             8908..9036
                     /locus_tag="TU818_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL0923632.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            9090..10403
                     /gene="obgE"
                     /locus_tag="TU818_000795"
     CDS             9090..10403
                     /gene="obgE"
                     /locus_tag="TU818_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL0923633.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            10524..10682
                     /locus_tag="TU818_000796"
     CDS             10524..10682
                     /locus_tag="TU818_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923634.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(10735..11439)
                     /locus_tag="TU818_000797"
     CDS             complement(10735..11439)
                     /locus_tag="TU818_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL0923635.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQSLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTSLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            11774..13174
                     /locus_tag="TU818_000798"
     CDS             11774..13174
                     /locus_tag="TU818_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL0923636.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQGKRGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVVLLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPSKTRQDGEPITLASYFEPYDMPGK
                     KVNPHRGWEIYEQGLYDIALNLKEHYGNIDWLVTENGMGVEGEEAFLVDGQIQDDYRI
                     AFIEDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            13184..14278
                     /locus_tag="TU818_000799"
     CDS             13184..14278
                     /locus_tag="TU818_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL0923637.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKFYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLAGLRLDEALP
                     LEDIVRLTKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRQLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPRVVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVANIKEDYLSLLDELKPWQEFSLVIETD"
     gene            14384..16378
                     /locus_tag="TU818_000800"
     CDS             14384..16378
                     /locus_tag="TU818_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL0923638.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLASKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEELCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HIMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            16392..16709
                     /locus_tag="TU818_000801"
     CDS             16392..16709
                     /locus_tag="TU818_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0923639.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALTMME
                     EEV"
     gene            16706..17041
                     /locus_tag="TU818_000802"
     CDS             16706..17041
                     /locus_tag="TU818_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL0923640.1"
                     /translation="MTQSSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTNLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEL"
     gene            17041..17475
                     /locus_tag="TU818_000803"
     CDS             17041..17475
                     /locus_tag="TU818_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL0923641.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKSKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEKRTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            17550..18929
                     /locus_tag="TU818_000804"
     CDS             17550..18929
                     /locus_tag="TU818_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0923642.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAAAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFVATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGARVLETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYATLTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGLGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPVFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVMSA
                     NKEKASDLS"
     gene            18926..19078
                     /locus_tag="TU818_000805"
     CDS             18926..19078
                     /locus_tag="TU818_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923643.1"
                     /translation="MTAKNGASFLMAIGFFLIAISPMVGNKYLHIVTGLAFVGLGYYL
                     TKRKRP"
     gene            complement(19235..19975)
                     /locus_tag="TU818_000806"
     CDS             complement(19235..19975)
                     /locus_tag="TU818_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0923644.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(19975..22140)
                     /locus_tag="TU818_000807"
     CDS             complement(19975..22140)
                     /locus_tag="TU818_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL0923645.1"
                     /translation="MKNTLKAWMLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDS
                     DQVYKGIDVDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKV
                     FHFSDPYYDTKIVIATRKANPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKT
                     FDTGDLMYNSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGY
                     DYLIDDFNEALGAMKADGTYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVA
                     DSSFAPFEFQIGSGEYVGIDMDLIKAIAKQQGFTIEISNPGFDAALNAVQAGQADAVI
                     AGMSITPARREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLE
                     SNKDIYGYRLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSG
                     EYGFAVKKGANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLA
                     NNYKQLLAGLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPL
                     MIVAAFIFWGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQ
                     MEASRSLGLSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
     gene            22332..24323
                     /gene="uvrB"
                     /locus_tag="TU818_000808"
     CDS             22332..24323
                     /gene="uvrB"
                     /locus_tag="TU818_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL0923646.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
     gene            24662..24805
                     /locus_tag="TU818_000809"
     CDS             24662..24805
                     /locus_tag="TU818_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL0923647.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            24817..26355
                     /gene="dltA"
                     /locus_tag="TU818_000810"
     CDS             24817..26355
                     /gene="dltA"
                     /locus_tag="TU818_000810"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL0923648.1"
                     /translation="MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAAL
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            26352..27599
                     /gene="dltB"
                     /locus_tag="TU818_000811"
     CDS             26352..27599
                     /gene="dltB"
                     /locus_tag="TU818_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL0923649.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSLSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMIFFPT
                     FSSGPIDRFRRFQEAYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLLLPLA
                     ENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNKPFLS
                     PNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVMGLWH
                     GLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKVFHALSIVVTFH
                     VVLFSLLLFSGFLNELWFSRPLR"
     gene            27617..27856
                     /gene="dltC"
                     /locus_tag="TU818_000812"
     CDS             27617..27856
                     /gene="dltC"
                     /locus_tag="TU818_000812"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL0923650.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            27849..29102
                     /gene="dltD"
                     /locus_tag="TU818_000813"
     CDS             27849..29102
                     /gene="dltD"
                     /locus_tag="TU818_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL0923651.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            29136..30110
                     /locus_tag="TU818_000814"
     CDS             29136..30110
                     /locus_tag="TU818_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL0923652.1"
                     /translation="MLMSIIVILLILAIAVLVIEYGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIHLTNAKLVFPNFEKAPYVTYKEIYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLMEQGHLNQLVIAEQMIHAYAIFPIREARQARKQIAELILKKE"
     gene            30651..31910
                     /locus_tag="TU818_000815"
     CDS             30651..31910
                     /locus_tag="TU818_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0923653.1"
                     /translation="MAWDWKKAGVVGVVSLASIMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPDVIETLVMYYNKDLVSEAPK
                     TFTDIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGAIEGLDYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     GKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            32083..33783
                     /locus_tag="TU818_000816"
     CDS             32083..33783
                     /locus_tag="TU818_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL0923654.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHNAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHQAVQDYLIEIGLYWITEYHIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQFGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            33812..35944
                     /locus_tag="TU818_000817"
     CDS             33812..35944
                     /locus_tag="TU818_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL0923655.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHGKNIKVVI
                     DFAPNHTSTAEYNGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLVFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGQHETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGNHDIKVTTSTGQSSSPYKAFEVLTDKQIPVRLVVNNFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAQYPNWFYDVNLPINKTINCHLVKKD
                     SSGKVLWTSPETYTIKTDSKAQTISLKK"
     gene            36020..37324
                     /locus_tag="TU818_000818"
     CDS             36020..37324
                     /locus_tag="TU818_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0923656.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQLYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIVFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRIFGVIFLLPWGVPAFISIMSFGNFFNDSIGAMNVQVLPFLEKFVPFAD
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            37325..38185
                     /locus_tag="TU818_000819"
     CDS             37325..38185
                     /locus_tag="TU818_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0923657.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQEHYTVAVGLQSFITNDARDPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            38210..39040
                     /locus_tag="TU818_000820"
     CDS             38210..39040
                     /locus_tag="TU818_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL0923658.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFARCSAFLWWQNVILVIFLNALVL
                     MPITLHYASLKSYPLEHIVSNGLDSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEEQALA
                     "
BASE COUNT        10866 a         7374 c         9044 g        11784 t
ORIGIN      
        1 tgatagtgga aattatcact caagaagtac ggggtatcag agcaagactt attttaatct
       61 gagtaagctt cttgtcctta ggctcaagct gatcaggact gagtgaccac ccatttaaac
      121 cggggaacaa ggtagctaac gataatgctg ctaagtccaa taatggttag ccaataaagc
      181 cagctggaat caaagctaag cacgagatga cttccaagga caagcacaac accagaccaa
      241 aacaagatta gattaatcgg gttatcagtg atagtgacct gatcttgatt ggtcacgatt
      301 ttcttggcct gcctgctatg cttgatggtc aaataatcct cagcatcggg gagatcaata
      361 tcgatactct cacccggata aagcttaacc ttgtgggatt tcccgatatt aactgtcata
      421 ggtgctccta tctttgtcaa acgtgtcttg cgccttagct tcattcctaa aatcctctct
      481 aaaataaaag tcaagcataa tcatgccaat tccagccttc aaatgctaca aaagaccagt
      541 gtaccatagc ctatgatacc aaaaagcaga aagaatagcg actgtaaaaa atctgaaaat
      601 aagctttctt acatctattc cctgctttga aagcagactt ttgcaggatc tatgctagaa
      661 tagaaggaaa aggagggcac taatggttaa gggaataata tttgacatgg acggcgtttt
      721 atttgatacg gagccttttt atctcaaacg tcgtgaagcc tttttgacga gtaagggcat
      781 taggattgac cacctcagcc ccgaggattt tattggtggt aatcttcagc agatttggga
      841 caaggtctta gcagggcagg ctaatgctga tgaggcaaga gatattgctg tggcttatga
      901 ggcctataag ctgtgccata agcctcctta ccaagagctg atgtttaaag gggtcaagtc
      961 ctgcctcaaa gctcttaaag ggcagggact taagcttgct ttagcctcaa actctagtcg
     1021 ttgtgatatt ttgttagctt tagagagcag tcatatcaag gcttattttg accttacact
     1081 ggcgcgtgag gacgtcacag ctggtaagcc taatcctgag atttataaca aggttgcgca
     1141 ggctctggga ctggctaaag cagagtttgt cgttgtcgaa gatagtcaaa aagggattgc
     1201 cgcagctaag gctgctggct tgaaggttct agcaatcaaa gacaagcgtt acggcattga
     1261 tcaaggtcag gcagacaagc gcattgatag cctcaggcag ctatgtgagc tgcttaggta
     1321 aggcttctga tagagcagat gtttgttaac tgaaagatag caggctttat agtggcttat
     1381 catcactaca atagaatgat ttgtcttaga atgacagaac ctaaataggt gtttttctcg
     1441 tttttgtagc aggatagctg aagcttttga tctgctttat gtttggtgtt gttattaaga
     1501 gatgaaattg tcagtaatgt tgagcttact gataggaggg ctaatggcag ttaaattatt
     1561 aacagaaaga ttgatcatac aggagttgaa tgagacctat tttgagcctt atcacaaggc
     1621 atttaccgaa gaaatcacag catttcaatg gcctgatccc tttaaggaca tcgctgctgc
     1681 taaggagaca ctagctagct ttatcgcaga aatgaaaaaa ggaaacatgc tagagctagt
     1741 cattttgaat aaagcaaatg acttcgttgg aagcttggaa gtctttagcc ttgatagtga
     1801 gacaccggaa ttgggcatat ggttgaaaaa atcaagtcaa ggactaggct atggctatga
     1861 ggccttgaga gctattgtgg attatttaaa aggcaaaaac aaataccgtt atttcaatta
     1921 tgaggtagat gttagaaata ctggtaatat taagctggta gagaaattca atgtggtgac
     1981 atcgacctat caggaatgtg agacggcttc aaagaaaagg ctttgtttac aggtttatca
     2041 cattcttaat taatcgttgg tatgacatag gtgatagtca tggttttgct ttaagtcctg
     2101 tgtgagttga gagcagcttt cagctctagt atttgcttct ggtgtggtct tttagtccac
     2161 agtctaggta ttataaagaa gagatctggc tttgtttaaa aaacagcttc tctgtctgag
     2221 cttgtaccct caagatatca ttgaagagat agcaggacag ctgttgaaaa tgagggaagt
     2281 aagagggatc tgtgtgccaa gatcaaaagc ataaaaagcc tctagcttac ttcttgtggt
     2341 tagcattttt ttgaaagcat gctaatttgc ctttagtgtg ctttttgttt gctcaagatc
     2401 agctagtcaa tgaggccata gagtaagcct taacaaatgg tgagatgtag ctacagccgg
     2461 ttgtgcagat ggggttagaa taattggatc tactcacagc ctcttgtaat catttcctta
     2521 caaaaatcac actagtaaag acctctaatg gcgaaggagc tcctgacacc aagctctgaa
     2581 gaagctggct atttgtcctt gatcaaaaag ggttaagact gtcagttcaa ctaggtgcaa
     2641 acgactcata aggcaggtct ttagcagggg tgatgtcaaa aaattgacat cagctgtaac
     2701 cttttagcaa aattgtagtc caacaaaagt gagcagacat tttggaaggg ggacctgtta
     2761 ttggaatttg aagacatcta cttgatgtat aaagacgatg tttatccttt tcttcatgcc
     2821 tatgcgtgag acaacttatg acgaggttga accaagggct ttctttatag tataatggtc
     2881 gttaaagtga tattaataag aaagtgatga ctataatgac agaaatacca aaggatttaa
     2941 agctaaatac gattagtgtc tttgagcatt atcatattga tgtgtttgag gctggtcatg
     3001 tgctgttatc aacagagatc catgcgtcag ccttgaacta ttatggaaat gcacatgggg
     3061 gctttttgtt taccctttgt gatcaggttg gtggcttggt ggccaaatca ataggtcttg
     3121 aggctgttac tctgcaagct aatgtgaatt atcttaagcc tggtcatcta ggagaccgtt
     3181 tagtcgtaga aggtagtctg gtgcatagag gtcggaccac acagctgatt gaggtcacca
     3241 tcaaaaatca agatgataga ctattaacca gggttagcct gaccatgttt gtgacaagta
     3301 aaaaacgatc ctctgactag ctgatacaag tcatatcaaa aaacgtccag cttgatttta
     3361 gctggacgtt tggctttagc tgcgatagag cttatggtgc tgataaacag ggtcaaaggt
     3421 cacattgata ccgagctgtc tgagaacatg cttgtcctcg ttggtcagga taacggttga
     3481 atgcgcttcg ctgcccttga gatttcctaa ttctttcatg gctagatcgg cttggttgtt
     3541 gttcattgct gtgatagcca gcgccattag gatttcatta gcgtgtagcc tagggttgtg
     3601 actgcctagg tgattaatct tgagcccttg aatgggcttg acatattctg gctcaatgag
     3661 atgcgtttcc ttactaatgt gggccagtgt tttgatagca ttgatgataa cagcagcggt
     3721 cggaccaaac aaatcagatg ttttaccggt gactacctga ccatttggaa gctgaagggc
     3781 tagggcaggc tgaccagtta tctctgcttt ttgcctagca atgagagtaa cctgtcgatc
     3841 tttgggagtg acaccgatgt cattcatcaa gagctcaagc tttttaactg cagcctcggt
     3901 cacgcgctcc gctttgaagt ctaccaaggt ttgatagtag cggcgaatga tttcttgcct
     3961 tgaggcttcg atagcagcct cctcattaac aatggaaaag ccgaccatat taacacccat
     4021 atctgttgga gatgcatatg gggactggct taaaatacgc tcaaaggttc tgtttagtac
     4081 tggaaagacc tcaatatcac gattgtaatt gactgctgtt ttcccgtaag cctctaaatg
     4141 aaagggatca atcatgttca catcatctaa atcagcagtg gcagcctcat aggctaggtt
     4201 tacagggtgg tggagtggaa gattccaaac agggaaggtt tcaaactttg catagcctga
     4261 tgtgacaccc tttagttggt catgatagag ctgtgagatg caggtcgcta attttccaga
     4321 gccaggacca ggagctgtga cgacaatcag gttacgactg gtcttgatgt agtcatttct
     4381 ccccatacca tcaggagaaa tgatgtggtt aatatctgtt ggatagcctt tgattgggta
     4441 gtggcgataa gacgtaatgc catttttggc taattgcttt tgaaaatgat ccgcagctgc
     4501 ctgatggttg tactgcgtaa ttacaactga gccaacatag atatctaagg cgttaaaggt
     4561 atcaattaaa cggagcactt cctgatcgta ggagattcct aagtcaccac gcgttttaga
     4621 atgttcgata ttattggcat tgatggtgat gacaatctca acctgatcct tgagctcctt
     4681 tagcagcttg attttgttgt caggctcata gccaggcaag acacgcgccg catgaaaatc
     4741 ctcaagtatt tttccgccaa attccatgta gagcttgccg tcaaattgct tgatacgttc
     4801 tagaatatga ttcctttgta agcttaggta tttgttggaa tcaaaagcaa tgtttttcat
     4861 ttatttttca cctctgctaa gcattatagc aaagaaatag tgagaagtga atgatttgtc
     4921 taaaaattag tctcttcctc taagtagcta gggtggcaaa aagcagcgct atttaaatac
     4981 cgataaaaaa tgacttgaca aaggtgactg acttgcttat actaggaaca attaaatacc
     5041 actttaatga tgttctgtga ggcatgaaag tgacaagaca aagaggagtg agcctgctct
     5101 tattttgctg tagactgaat gcgactgatg gactggtgcc taggtctttt ttaatgggct
     5161 taaagggtat tcaattaatt aaggtagtca gtgagctact attaaaagga gaataatcat
     5221 gtcagcattg tctttagaca agaacaacaa gcgtgcgctt tgggctgcta ttgccgcttc
     5281 aggaacagat gatcttaacg ttatgtttct agccttttcg atgtcctcta ttatctctga
     5341 tctaggagtg agtagtactc aaggaggctg gatagctact atcactaatc taggaatgct
     5401 ctttgggggc ctgctctttg gtctgcttgc tgatagacat cataaattta aggtattcaa
     5461 atggacgatc cttatttttt cagtggcaac aggcttgatt tattttacca agacgattga
     5521 atttttatac ctcatgcgct ttattgctgg tattggggtt ggtggtgaat atggtgttgc
     5581 tattgcgatt atggcaggac ttgtccctgc tgaaaaaatg gggcgcgtct catcgctaaa
     5641 tgggattgca ggtcaggttg gatcaattgt ttctgcttta ttagcaggct ggctagcacc
     5701 tgctcttggc tggcgcggcc tctttctctt tggtctggct ccgattttac tagtcatttg
     5761 gatgatggtt gctattgatg atgataagat tattgataac catgtcaatg tttcagagga
     5821 agctagtcag ccggtaaaga ttagtgagtt atttaagaca ccagccttga caggacaaac
     5881 tctcgctttg atggtgatga cgacagttca gattgctggt tattttggta tgatgaactg
     5941 gctgccaact attatccaag ctagtctaca tatttctgtc aaggattcgt ctctgtggat
     6001 ggtatcaacc attgtgggca tgtgccttgg aatgctgacc tttggccatc tgctagatac
     6061 ctttgggcca agattggttt attctatctt tttgcttttg tcctctgttt gtgtctatct
     6121 ttttcagttt gccaattcga tgtcaaccat gcttattgga ggagctattg ttggattttt
     6181 cgttaatggc atgtttgcgg gctatggtgc gatgatcaca cgactctatc ctcatcacat
     6241 tcgatcaaca gctaataacc ttatcctcaa tgttggacga gctgttggag gcttttcatc
     6301 ggttatcatc ggtaaaattc ttgatgtttc aagtgtctct atggtcatgc tctttttagc
     6361 cctgctgtac cttgttagct ttgtggcttt gtggacaatc aaaaatctaa aggcagagcg
     6421 atatcaagcg ctgacaaaat agatctggta agtgtagtag gattagtagc aaaggttttg
     6481 ttaaagctct caaaaagcgc ttaggcattt agactaagcg ctttttgacc tttaaagctt
     6541 ttccaaaaag gcgtcttggt caaccctgac acgtgtgtgg caggctctgc caatgagctt
     6601 atggttggca aaggcttcga tacgaaagtc gtattttctg ccctcttcct tgagtgcagt
     6661 gataacaatg gttactgcct gaccgatttt agaggcagct aggtgctgga tagcgatttc
     6721 acttccaacg gttgtttgct tgtcctttag ctgactttgc agaaacgtga aggcagcatg
     6781 ctccataaag gcgacaagag caggtgttgc taggacctct aagccaccag agcccattgc
     6841 ttgagcagaa tgcttgcttt ttgtttcgta tagctgtgaa taaatagaca tgataccctc
     6901 cttttttatt attataatat attaagggct tacagtctta aatgagctgc cttttgtgct
     6961 atactaagaa ttagcttgaa agagctgttg ctgaattaat gtgtctcgca tgggccagac
     7021 taagcatcag ctaacagtaa gaagaagggg aatacatgcg cttagataag tttttagttg
     7081 atgctggctt aggcagtcgc agtcaagtga agctgctatt aaagaaaaag caagtcagtg
     7141 tgaatggggt tagccaaacg tctccaaaat atcaagtcaa tgaaatgacc gatgaggtta
     7201 gctatcaggg acaaaggctc aattatgagg cctttgtgta ttatatgctt aataagccta
     7261 aaggagtgat ttctgcgact gaggattcta gccataagac agtgctggat ttgttagatg
     7321 atactgcacg tcaaaaggct gtctttcctg ttgggcggct tgataaggat acgcatggct
     7381 tgctcttagt gaccaatgat ggaaagctag cacatgctct tttgtctcct aaaaagcatg
     7441 ttgccaagca ataccttgct gtggtagacg gtatgatgac tcaagaggac gtcaagcatt
     7501 tcgcacaggg aatcacttta aaggatcacc aatgcatgcc agcacatttg gacattcttg
     7561 agattaacga atcgctaaaa accagccttg tcaaaatcac catcgaggaa ggaaaatttc
     7621 atcaggttaa gcgaatggta gcagcctgtg gtaaaacagt cagcgattta cagcgcatta
     7681 gtatggggcc cttacagctt gatagtgctt tggcgcctgg agcctatcgt aggttaacag
     7741 cagcagagct agaggctggc tgggttagct gctgaattga tagtaaaaaa gaccagtctt
     7801 agactgatct gtagggtgat tagatcgccc attctcctcc tcggaagatt ggaatgactt
     7861 ctccgtcttt ggtaatgcca tcgatatcca tttgttcaga accaatcata aagtccgcgt
     7921 gggctgttga gcgatttagg ccagccgctt cccaaatgtg ctgctcaggc attccaagtc
     7981 ttaggtcagt tcctggtgcc ctgtagtgaa ggctgtcaaa ctgataatca ttgaggagcc
     8041 ttgccttttt ttctaaacgt tcctgatgtt ggtcccaggc cttgacagga tctgtctcgt
     8101 aaatgcgatt cattttgaaa atggcatccc acaaagcgtc cacctgctct tcttcgcttg
     8161 tcaggtttgg aaaaaccata gcagcccatt cgggaccggc tgcagctgct agattccagc
     8221 tgactttgtt ggcctgagtg gcagcccgct gtttttcaag agcaatagct gttgcgcgtg
     8281 ttgctccagc tagcctatca gaatcaatat cagcaaagac gtttggattg gcagagcgaa
     8341 tgactaagcg gcttgctttt tgatcaagga gataatgtga ctgttcaacg acataatctg
     8401 gtacctgcaa gagacggtct tcatcagcct taagaagctt ctcgcgtgtg atctgatcgt
     8461 cattatagtc aacaagaacc tcagctgcac cagcctcata ggcttttttg gttaatagcc
     8521 gcgcaagctt gtgttgctct actgcaatag aaatgagtag tgtgtgacct ttttgaatgt
     8581 tgactccttt tttgataaga aggttagcgt atttttcaag ataatcgtca aaatgtggca
     8641 aaaccatagc agtctcctaa tatgttaatg ttgcaaaatt taatgtatca tatttgcgac
     8701 tatttcacaa ggagctagcc tgtttcatag gctaaatgtc tcctagaatg cctatcgtaa
     8761 aaggctcagt gttggttttc tctgatgagt taaaaaacga tccctttttt gatcagtttg
     8821 cgctgccctt gctaatagat atttgcttaa tagcgacatt cgtgttaaga tataagagga
     8881 aaaaatcaat agatgaggta tttaacagtg gcatttggag aaaatggacc tcgcaaaaaa
     8941 actgcctttg aaaagttgac aacagttgtt gtgatcgtga tggttcttgt gactgtcggt
     9001 ggacttattg cgggtgccct gtcagtattg atgtaagaaa acgctgaaag gcgttttttt
     9061 aggataagag aaggtttgag aagaaaagta tgagtatgtt tttagatact gctaaggtca
     9121 gtgttcaggc tggtcgtggc ggtgatggta tggtggcctt tcgtcgtgaa aaatatgtgc
     9181 ctaatggcgg cccttggggc ggtgatggtg gcaagggtgg ctctgtcatt ttcaaggttg
     9241 atgaaggttt gcgtacccta atagactttc gctacaatcg taagttcaag gccaaatccg
     9301 gtgaaaaagg catgactaag ggcatgcatg gtcgtggctc agaggatttg attatctcag
     9361 tgccacaggg aacgactgtg cgtgatgctg aaaccggtaa ggttctgacg gatctggttg
     9421 agcatggtca agaatttgtc gtggctaagg gtggtcgtgg cggtcgtggg aacattcgtt
     9481 ttgcaacgcc gcgcaatcca gcacctgaga ttgctgaaaa tggtgaacca ggagaggagc
     9541 gccaattaga gctagagctt aagattttgg cagatgtggg actggttggt tttccgtcag
     9601 ttggtaaatc aacgctacta agcgtggtct catcagccaa gcccaagatt ggtgcttatc
     9661 actttaccac tattgtgcct aatctaggta tggttcgaac caaatctggt gagagctttg
     9721 ctatggcaga tcttccaggc ttaatcaagg gagctagcca gggtgtgggg cttggcactc
     9781 agtttttgcg ccatattgag cgtacacgtg tgattctaca tgttattgat atgtcagcag
     9841 ctgaaggacg agacccttat gaggactatg tggcgattaa taaggagtta gaagcatata
     9901 atcttcgtct tatggagcgt ccgcaaatta tcgtcgccaa taaaatggat atgccagagg
     9961 caaaggagca gttgcagcgc ttcaaggaac agttagctgc tcagtatgat gactttgaag
    10021 aactgccaat aattttcccg atttctagct tggcacatca aggcttggat agcctattag
    10081 aagcaacagc agagctatta gcaaaaactg atgatttctt gttgtatgat gaggctgatt
    10141 tggctgagga cgaggcttat tatggctttg cggctgagga aaaggccttt gagattagtc
    10201 gtgctgatga tgcagcttgg gtattgtctg gtgagaaatt agagcgtctc tttgtgatga
    10261 ccaatctgga gcgcgacgaa tctatcatga aatttgctcg tcagctacgt ggcatgggtg
    10321 ttgatgaagc gcttcgtgag cgtggtgcta aggacggcga cattgttcgc attggcaagt
    10381 ttgagtttga atttgtagac taatgacaaa taccaagctt agctgttttt tgtagcaagt
    10441 gatgctgagt catatctgaa gtaggctgtt tgctcaattc acagcaatga ggtcttggtt
    10501 gatgtgagct agggaggttt tttatgggag ataaaccaat atccttcaag gataaggacg
    10561 gtaactttgt ttcggcagca gatgtctgga atgctgaaaa attagaagaa ttatttaatc
    10621 tcttaaatcc caataggcgt ttgcgtttgg aacgtgacaa attaaaaaag gatgaagctt
    10681 aagtgcactt cctctcaatc gttagattta gtgtctaact tttgagggtg cacttcaagg
    10741 cttcgtcctt ttttgatgct ttttttcttg gtgatgctgc aaatgtagcc aattaaaaaa
    10801 ggtgtaaatg tcattaacaa gaaaggctgc aaaacaaatg accactgcgt attggctggt
    10861 atttgcttga gcagcataga gccacaggag aattaagacc aaatcattaa gagcataggc
    10921 caaggcaaaa taagggctac gtttgtagct taagtaggct gctgaaaaag aggtggcaat
    10981 agataaggta gaaacaggca gataggctgt cttaagatag gctaagatag catagaacaa
    11041 gctggtaact agtatggtaa gaaccactaa gcgcagccgg tctgctgttg tcaagcgtga
    11101 gatggttacc tgagatgtct ggtcttcaaa tgggtggctt agccaggtaa acagtgacaa
    11161 aatagccatc ggcagggtca tgaagagata ggttatcagc tccccgtaat aactgtttaa
    11221 tagtgacaga taggcataaa taagggagaa aataatggcc aagctctgtc caatcggatt
    11281 tgccttggca ctaaagatta aagctgtcac accgattaag gaagctatca gtgctaaggg
    11341 agcttgttct ccaaagaaaa aggcactgag gagaatagcc gaaatggagg ttaaccaaag
    11401 cgtccactcg gtttttgtaa aatagtttaa ataagccata tccttattca agcataggcc
    11461 tttttatctg tcaatagggt gtcgacctta gggaaaaata agctaatacc tgccatagtg
    11521 caattggttg tgaggcacta atactagcag ataatggtgt taactagagg caaatgagct
    11581 aagagtttcc ttattggctg ctgctaatac tccttgttga ctggtttaga agaaaaggac
    11641 taagagcctt agcttggctt tgtcagttag tttccttgat gataaggaaa aactagattt
    11701 tttaaagcgt ttacagtgtc cttttttctt cctataatag gggtataagt gacaaaaaga
    11761 aaggaaaaag catatgaagc aatcaaaacg ccgttaccaa tttccagaag gttttttgtg
    11821 gggaagctca acatctggcc ctcaaagtga ggggactgtt tctggagatg ggaagggacc
    11881 tagcaattgg gactactggt ttagtctgga gccagataag tttcatcatc agattggtcc
    11941 agaggtaacc tcaacctttt acaccaacta caaaagcgat attgctcttt taaaagagac
    12001 cggtcacaca gcttttcgga cctctattca atggtctcga ctgattccag aaggggttgg
    12061 tcaggttaat ccaaaagctg tagcctttta ccgagaggta tttcaggaaa tcatggctca
    12121 ggacattaag ctgattgtta acctctatca ttttgatctg ccttatgcct tgcaaggaaa
    12181 gagaggctgg gaggctaagg agacggtctg ggcttatgag acctatgcta agacctgttt
    12241 tgagcttttt ggtgatttgg tggatacatg gattaccttt aacgaaccta ttgttccagt
    12301 cgaatgcggt tatttggggc attaccacta tccttgcaag gtagatgcca aggcagctgt
    12361 tcaagtggct taccataccc agttggctag ctcacttgct atcaaggcct gccacgagtt
    12421 gtatcctaag cataggatta gtattgtgct taatgtgact cctgcctatc ctagaagtga
    12481 tcagccagaa gatgtcaagg cagcgagaat cgcagagctt ttccagacta aatccttcct
    12541 agatccgtct gtcttaggag tgtacccaga agagttagta gttcttttag aggcagctga
    12601 tttattgccc cagtatagtg ctgatgaatt ggctattatc aaaaacaatc ctgttgattt
    12661 cttgggagtt aattactatc aacctttgcg tgtgcaagcg cctagcaaaa caagacaaga
    12721 tggtgaacca atcacgctag cctcttattt tgaaccttat gatatgccag gcaaaaaggt
    12781 taaccctcat cgcggttggg aaatctatga gcagggcctt tacgacattg ctcttaattt
    12841 aaaagagcat tatggcaata ttgactggtt agtaactgaa aatggtatgg gagtagaagg
    12901 tgaagaagcc tttttagttg atggtcagat ccaagacgat taccggattg cctttatcga
    12961 agaccatttg attcaattgc acagggcttt agaagaaggc gcgaactgta aaggctacct
    13021 cctgtggacc tttattgatt gctggtcttg gttaaatgcc tataaaaatc gttatggctt
    13081 ggtagccttg gatttagaga ctcaaaaacg aacccttaaa aaatctggcc actggtttaa
    13141 gaccctgagt cagacaaatg gttttgataa ataggagcgt atgatggtca ccttaggatt
    13201 ttccctttac cctgagcggc atggttttgc taagagtaag gcttatattg atttactgca
    13261 ctgctatgga gccaagcgct tgtttatgag cctcttacag ttggcgccaa atgatcccaa
    13321 gacctttaag ttttatgcgg atctgattgc ttatgccaat tgcttgggca ttcgggtcat
    13381 tgcagacgtt agccctgctt ttatcaagca ggctggttgg tcagatcagg ttattgaaga
    13441 ggctcatgct tttggcttag caggcttgcg tttagatgag gccttgcctt tagaggatat
    13501 tgttaggcta acgaaaaact cttttgggct taagattgaa ctcaatatga gtactgacaa
    13561 gagtttattg acagccttgc taaaggcagc tcctgatcgg agtaacctca ttggttgtca
    13621 taatttttac ccgcacgcct ttaccggcct gtcactggag cattttaagg aaatgtccca
    13681 tttttaccac gagcatggga ttgcaacggc tgcttttatc acagcccaat cagcaaagga
    13741 aggcccttgg ccgctgtcag agggcttacc gactgttgag gctcatcggc aattgccaat
    13801 tgacgtgcag gtggaactga tgaaggcgac aggaactatt gatactgtca ttttgtccaa
    13861 tcaattcatc actgaagatg aactcgttca gtgccgtcaa gccttggata gatcagtcat
    13921 gtctattaag gtcaagcctc tggttgattt gacggacata gaggagaaga ttatctgtta
    13981 cccacattgt tatcggggag atgtatcaga ttatgtgatt cgctcaacca tgccgcgtgt
    14041 ggtatatgct caagaagcaa ttgctccaag agagcagccc aagcaggtta agcgaggcag
    14101 tattatcatt gataatgacc gttacaacag gtacaaggga gaattgcaaa ttgcactcaa
    14161 agcctttacc cttagctcaa aggccaatgt ggtcgccaac attaaagagg attacctaag
    14221 cctattagac gagttgaagc cctggcagga gttttcattg gtgattgaga ctgactagtc
    14281 tggcttcaca atcgatacgg aaaatgatgg tcactttttt caggaaacat ttgctaaact
    14341 aagagagtaa agaaagcgtt ttctaaaaga cgaaggagga atgatgctat caaaaaaaga
    14401 aatggctata gtagcatttc taatcagcca aaaagggcag tttgtctcta gtgctacctt
    14461 ggctaaggct attggcatga gtgatcgcac agtcagaaaa tacctaaagg agctgattag
    14521 cagccttcct agtaagggag cgcacatcat ttccaagcaa ggtcagggct actgtttaga
    14581 gattgatcat tctatggcgt ttgagatctt ttggcaggaa agcttggcct ctaaaaagcg
    14641 cttggctgat gtgactcagg tggaagaaac agttgatcgg gagcattatt tgctaaataa
    14701 attcttcttt gaagagcccg tttgggattt tgaagagctc tgccaagaat tgtatattag
    14761 tcggacgacc ctaaaccatg ttttagcggt tattagagac cgtattaggc cttatcagct
    14821 acagcttgat gtgagtcatc agcgcgttca ggtgacaggt aaggaagagg ctattaggca
    14881 ttttatcatg gattattttt ttgctaccag ctttgatgac tccatgtacg ccatagtaga
    14941 caataccttt cttgatcata tcaagtttgc tgatatcaca ataattgttt tagatgaatg
    15001 tcgagatgcc aaactaaagc tttctgattt tgtcatgcac aatttggttt tgcacattgc
    15061 cctaatggtt cagcgtattc ggtctggcta tccgttagca tttttttcca ttccagcagc
    15121 tattcgccaa tcagacgagt atcaagtggc tctacgtatt ttatatcgag tagaagaagt
    15181 gatgggcatt cgttttccta aagaagaagc taactatatt gctttacacc tcaaggttaa
    15241 gcattccgtt gatggcagcc cacaggacaa taaggccgat gacttgctga gaagtcattt
    15301 aaaagcaggt attgtcaagg ctagtcagct gacaggtatg tctttggagg ctgatagcag
    15361 cttgcttcaa ggcctattgg cccatatgaa gcctttagcc acaaggcttg aaaatcatat
    15421 tcagctgacc aatcccttaa ctgaggagat taaaagcaaa tacccagagg cttttgccct
    15481 gactaagcaa gcttttgaga atattcctga gcttcaggct tatgacctgt ctgatgacga
    15541 atgggcttac attagcttgc atatcatggc agctattgag cgctattcca atcgtcacaa
    15601 actgagggtg cttgtggttt gtgccacagg ctatggcagt gccatgatgc tgaaaaatcg
    15661 cttggaaaag gaatttgaag gtcgctttca gattgtagat gttatcagct actatgaaat
    15721 aacacaggaa cgactgcaaa cggttgatgt gattatttct tctatcagcc ttgctaatgt
    15781 catgttttta acgccagtca ttactgtcag tgtcttttta tctgatcaag acatcaaagc
    15841 cattcgccaa tttatcgggg agcaggaggg aataagaaga gaagctgcgt cgtcatcgca
    15901 gatgagcttg gaaaaagcag agcagattct aaaaggtgtc tttagtccta agcgttttct
    15961 ttatgtgaaa gaaaaactat caaagaaggc cttgctgtta aagatgattg cttgtcttga
    16021 cgaagcaatg gatgaagcct ttgttgaggc cttttatcac caaatcgtgt tgagggaaaa
    16081 ttatagctca attgtttttg gtgaggtgct tgcctttcca cacccggcta atcccatgac
    16141 ctattctgaa caggtggtgg tggctgtctg tcaagagcct attgactggg acgagagtca
    16201 tcgggctgtt cactttatct ttttgttgtc accgtccaag ggacgtaaca gctatttaaa
    16261 atatatctca ccgagcttgg tgtcttttgt caatcaagca gagcttcagc aggctttatt
    16321 agaagaacca agctatgcac aattcatcac attatttacc ccactcatca ctgaataaaa
    16381 ggagaagtat tatgaaaacc attatgttag tttgtaatgc cggcatgtca accagtatgc
    16441 tggtgactaa aatgcaaaaa gccgctcaag cgcgtggcat cgaggttgag atttgggcag
    16501 ttcctgtgag cgaagctgac aatgaggttg ctgctaaaac cattgatgtc ctcatgttag
    16561 ggccgcaggt caaattctta ctaaaggact ttaagaccaa atttgaaccg gcaattaagg
    16621 tagatgtcat taacatggct gactatggcc tcatgaatgg tgacaaggtg cttgaaacag
    16681 ccctaacaat gatggaggaa gaggtatgac acaatcatca aacctagagg ccattatggg
    16741 attaatcatg tatggcggtg aggccaaggg caaggctgta gaagctattc atgcagctag
    16801 agatggtcaa tttgaaaagg ctcagcactt gcttcaagag gctacacatt ctttaaatgt
    16861 tgcccataga tcacaaacca atttgctatc tcaggaagca gctggagatc aggttgattt
    16921 gtctttattg ctggtgcatg gtcaggatca tatgatgaca gccttagcct ttattgattt
    16981 ggccaaggaa ttggtcgctg tttatgacaa aatatcaaga atccaaagag gtgagctatg
    17041 atgatgatta cagcagaagg agatgtctct gtcactcaat gcttcaaggc tatactaagc
    17101 tctctccaag aggattatca tgaaaacacc ctgagacggc tgccaccagc tgaattaaaa
    17161 gcagggctaa gctacataaa gcattatggc aaaagcaagg agcataacgt tagagtgctg
    17221 atcacagcct tagaagctcc gcacttatat gctgcttgct ttagctctaa tcatgggcta
    17281 aaaacattaa gctaccgctt agaagctctg ggagagaagc gtaccaaaat aacctattgc
    17341 tacgactatc agccacttga tgtctttcaa aaagccaatc agctgatcat tgggaagctt
    17401 tttaagaaga gcttcaaacg gcaatcacaa gcccaattgg cagcccttat ccaatatgct
    17461 aagcagctaa gctaggggaa gatttgagta cagattatct ggctgattat agggcttatc
    17521 atactaaaaa atagaaacag gagaaaatta tgtcacattt ttcggataag tttatggaga
    17581 tttcaggaaa gatgggatcc cagcggcatt tggttgccat tcgtgattcc tttatttcgc
    17641 taatgcccat cacgatggcg ggctctgttg ccgtcttgct gaatgttttc ttgcgtgata
    17701 ttccaaacaa tatgggctgg actggttttg cagcagccat gcagcccatt attgacatca
    17761 atggttatgt gtattttggg acaattggta tcatggcact cttttttgcc tttgcttttg
    17821 ggtatcattt agctcttatg cacaaggtga atcctttggc tggaggttta atctcctttg
    17881 cttcctttgt cgccaccctt cctcaaagct taaccatttc cacaccactt gaaggggcgt
    17941 cagcaagttt attagcaggc ttaaaggata tgggactatc agtggtcact gcaaatggag
    18001 cccgagtttt agaaacaagc cagtggggag caattgccct caaatatgct ggagcaacag
    18061 gtctttttac agcattgatc attggctttt tatctagctt tgtttatgcg actttgacca
    18121 aacgtaacct gaccatcaaa ttgccagata atgtgccacc tgcggttaat aaggcttttg
    18181 cggctattat tccagggaca gtcgcgattt atgtgtcagc gatcgtagct taccttattt
    18241 ttgccctcac aggctcgtct ctaagtgata tgatttcgac ctatatccaa ttgcctttgt
    18301 tggggctgtc tcaagggctt ggctctgtta tcctgttaac cttcttggtt caattgctct
    18361 ggttctttgg tttgcatggt cacaatgtct tagcacccgt gcttgatggt gtgtacttag
    18421 tggctctaac agaaaataca gctgcctata ataccagtca gagcgttgct aatctgcctt
    18481 atctctggac gagaggctcc tttgatgcct atgcacaaat gggtggttca ggtgttactc
    18541 tggctctgat tattgctatc tttattttct caaaacgtga ggagcacaag accattgcca
    18601 aattatcagc accgatgggc gtgtttaaca tcaatgagcc aattaccttt ggtatgccta
    18661 ttgtcttgaa cccaaccttt gctatcccat ggctaatcgt accaccaatt tgtgctagca
    18721 ttgcttatgc tgccacagca ataggcttga tccctcccgt tttcttgcca gttccttgga
    18781 ttacgccagt tggactttac gcttacttgg ctactggagg tagtgttatg gcaggtctgg
    18841 tttccttgtt taacctcttt gttgcctttc ttatctgggc accatttgtc atgtcagcta
    18901 ataaagaaaa agcgagtgac ctttcatgac agcaaaaaac ggagcaagct ttttaatggc
    18961 tataggattt ttccttattg ccattagtcc aatggttggc aacaaatacc tacatatcgt
    19021 gacaggacta gcttttgttg gcttagggta ttatctcact aagcgcaagc gtccttagtc
    19081 aatgcgagca gctagcccct atgaaaagac aaacctaagg gctagccttg attttctatc
    19141 ttggttatcg catttaaaag caagcaaaaa agcaagggta gatgcttacc tttgcttttt
    19201 ttattttttg acctttaata gaatatcttg ctacttaaac atttaagacc ttatctaaaa
    19261 attcaattaa gcgtgggtgc ttagggtgat caaagatttc ctctggagta ccgtcctcta
    19321 ggaattggcc gccgtctgta aagatcacac gattagccac ttgacgagca aagcccattt
    19381 catgtgtcac aatcagcatg gtcatgccct gctctgctag gtctttcata acgtttaaga
    19441 cgtctccaac catctcaggg tcaagagcag aggtaggctc atcaaagagc atgatatcag
    19501 ggttcatggc aagacttctt gcaattgcaa cacgctgctt ttgaccacct gatagacttc
    19561 ctgggaaagc gtcagcctta tcagctagac cgaccttctc tagaagagca agtccctttt
    19621 ccttagccgc ctcctttgag acctttccaa gctcaactgg tgcaaaggta atgttatcaa
    19681 ggactgtcat atgtggaaag agattgaagt gctgaaacac catgccgata ttttcacgag
    19741 ccttatcaat attggtatta ggatctgaaa gttcaaagcc atcaaccaca accttaccac
    19801 tagtaatgga ttcaaggaga ttgagggtgc gcaggaaggt tgattttcca gagccagatg
    19861 gcccgataat acaaacgaca tcaccctcgt aaaatttagc attaatgcct tttaagacct
    19921 cattttgccc ataggatttg tgtaaatctt gaacatcaat ttttaattct gccattagtt
    19981 aagcctcttt tctaaacgtt ttgcaagcct tgttaagagt gtaatcataa tcaagtagat
    20041 aactgctagg atagcataca tgcggaagga ttgatagttt ctagcgataa tgattttccc
    20101 tgtttggaag agctccacta aaccgatcgc tgagactatg gtcgtatcct tcaaggaaat
    20161 gacaaactga ttgatgaagt ttggcagcat tagcttaatg gcctgaggaa ggataatcct
    20221 tcgcattgtt gtgtgatatg acaagcccaa gctgcgacta gcctccattt gacctgccgg
    20281 cacagcctcg atacccccac gaacaatttc ggcaatatag gctccaccat ttagcgaaag
    20341 tgcaatagta gcagctacaa aatcgttaat cggtgattga tgcccagtca tgctttcaat
    20401 gaggtttggc actccccaga agataaaggc agcaacaatc atcaagggga taccacgcac
    20461 cacatcaaca aagatagtag aagccatgcg caggttcttt gatggggata cagccatcat
    20521 tccaaaaaca ataccaataa ccaaagcaat ggcaaaggag atgagtgtca gaccaagggt
    20581 tgttccaagc ccagccaata attgcttgta gttattagct aaaagtccat aaatagttga
    20641 ctcatcggct gttttgacag atgcctctga atcaaggtat ctgctgatga tggcgtcgta
    20701 ttttcctgat gctttaagag cagccaaacc gttgttaaac atttcgatga gctcagggtt
    20761 ggctcctttt ttaacagcaa aaccatactc accagaaggc tctcccttga taggaatatc
    20821 aagcttgtgg cctcgctgaa tagcgtacct taaaatagct tcatcatcca taagcccgtc
    20881 aatagaacca gaatttaagc tatcgtacat tgaggaggcc tcatcaaagg cttttagacg
    20941 gtaaccataa atatccttgt tgctttcaag gaaatcatag gaggctgttc cttttttggc
    21001 accgactatt ttacccttga ggtccttgta tgatttgata gagcttccgg atttgacccc
    21061 aaggcgaatg tttgatgtgt agtaggaatc tgaaaaatca aaaatctcac gacgtgcagg
    21121 tgtgatagac atacctgcaa taacagcgtc agcctgacca gcttgaacag catttaaagc
    21181 agcgtcaaag ccaggattgc tgatctcaat ggtaaagcct tgctgcttag caattgcctt
    21241 gatgaggtcc atatcaatac cgacatattc tccgctgcca atttgaaatt caaagggagc
    21301 aaaggaggag tcagccacga ttttataaac cggctttaaa ggagtggcct tagcagaggc
    21361 atcgccagta gccttgcctg ctgtgacctt gtcattgctg ccaagccatt ttgtcatgat
    21421 agcttgatag gttccatcag ccttcatagc gcctaaggct tcattgaagt cgtcaatgag
    21481 ataatcatag ccgctgcctt ttttgacagc aaagccaaag cttccaatag cctctccctt
    21541 catgttgatc gcaagatcct gcttttggtt aatggcatat tgaatgacag gctcgtcgtc
    21601 cataacagcg tcaatagagc ctgttgcaag actgttgtac atcaggtcac ctgtgtcaaa
    21661 tgttttaaca gtataaccat acgatttttt gtatttatct aagaaggctt gagcagctgt
    21721 tccattttta acaccgactg tttttccttt tagctcgcta tatttcttaa tagggttagc
    21781 ctttcttgta gcaataacaa tttttgtatc gtaataggga tctgaaaaat ggaagacctt
    21841 ttgacgagca gcagtgatgg tggtgcctgc cataagggcg tcagcttgac cagactgaat
    21901 ggcattgaca gcagcatcaa agccagggaa tgtcatattg atattccaac cctttcgctt
    21961 tgctacttca ttgatgatgt caacatcaat ccccttatac acctgatctg aatccttgaa
    22021 ttcaaacggt gcataagcag tatcagaaac aatatcaatt gtctctgcac ttgcaatccc
    22081 agcagtcatc aaaacaactg acagcattgc aagcatccat gcttttaatg tgtttttcat
    22141 actagtctcc ttaataaaaa taaaaaatat gcctaattat agcagatttt tttcaaacaa
    22201 gcaaatcatc tcttcttttt atgtcataaa acctaacata aacaactaaa atagtcaaaa
    22261 agctttgata gagtctttaa gtccttaact atgttacaat agataagaga taagatattg
    22321 aggaccaata aatgattgat aaacgtgatt ttaaagcatt taagctcgtg tcaaaatatg
    22381 ccccctcagg agatcagccg caggcgattg agaccttggt tgataacatt gaaggtggtg
    22441 aaaaagcgca gattttacta ggagcaacag gaacagggaa aacctatacc atgagtcagg
    22501 tgatcagcaa ggtcaacaag ccaacgttag tggttgctca taacaaaacc ttggccggtc
    22561 aattgtacgg tgagtttaaa gagttctttc ctgaaaatgc tgtcgagtac tttgtatcct
    22621 actatgacta ttatcagcct gaggcctatg ttccttctag tgatacctat attgaaaaag
    22681 acagctctgt taatgatgag attgacaagc tgcgccattc ggccacctca tcgcttttag
    22741 agcgtaatga tgtgattgtt gtggcttcgg tttcttgtat ttacggattg ggctcaccaa
    22801 aggaatatgc tgattcagct gttagcctgc gtcctgggca ggagatatcc agggatcagt
    22861 tgctcaatgc ccttgtagac attcagtttg aacgcaatga cattgatttt caacgtggac
    22921 gctttcgtgt gcgtggtgat gtggttgaag tatttccagc ctcaagagat gagcatgcct
    22981 ttcggattga gtttttcggt gatgagattg atcggattcg tgaaattgaa agcctaacgg
    23041 gtaaagtatt aggtgatgct gatcatttag tgctttttcc ggccactcac tttgtgacca
    23101 atgatgagca catggagcag tctattagca agattcaggc agaattagca gaccagctta
    23161 agctatttga agcagaaggc aaattgctag aggctcagcg cctgcgtcaa aggacagaat
    23221 acgatattga aatgctacgt gaaatgggct acaccaatgg ggttgaaaat tactcacgtc
    23281 acatggacgg gcgttcggca ggagagcctc cttataccct gttagatttc tttccggatg
    23341 attttcttat catgattgac gagagtcaca tgaccatggg acaaattaaa ggcatgtaca
    23401 atggagacaa ggctagaaag caaatgcttg tggattatgg ctttcgtctt ccgtctgcct
    23461 tagacaatcg tccgcttcgt cgggaggagt ttgaaagtca tgtgcaccag attgtctatg
    23521 tctcagcaac gcctggagat tacgagatgg agcagactga tacgattgtg gagcagatta
    23581 tcagaccgac aggtctgctt gatccagagg ttgaagtccg gccaagcatg ggacaaatgg
    23641 acgacttgct tggcgagatt aacctgaggg ttgaacgagg tgagcgcacc tttatcacaa
    23701 ccttaaccaa gaaaatggcg gaggatttga ccgactacct caaggaaatg ggtgtcaagg
    23761 taaaatacat gcatagcgac atcaagacat tagagcgtac agaaattatt cgcgaccttc
    23821 gtttaggcgt ttttgatgtc ttgattggta tcaatctgct gcgtgaaggt attgatgttc
    23881 cggaggttag ccttgttgct attcttgatg cggataagga aggcttccta agaaatgaac
    23941 gaggtttgat tcagacgatt ggtcgagctg ccagaaatgc tgatggtcat gtgattatgt
    24001 atgctgatcg tatgacggat tccatgcagc gcgctataga tgaaactgct cgtcgtcgtg
    24061 ccatacagat ggcatataat gaagagcatg ggattattcc gcaaaccatt aaaaaagata
    24121 ttcgtgattt aatcagtatt tccagagcag ttgaagcaaa agcaacagaa gcagagacaa
    24181 attatgagtc aatgacgcgg tctgaaagac aagaagctat taagcaattg caaaaaaaca
    24241 tgcaggaagc agcagagctg ctggattttg aattagcagc acagcttcgt gacctgatct
    24301 tagagttaaa agcaatggat taagacctga taagctaagt ctggctgtat aagctaggct
    24361 ttttatctgc ttttgagttt gtcctttagg tctgtcttat gatctttggt accagataaa
    24421 tgagtgatat cttgagcttg atctacgcaa gagctagtgc agccactagc ttcagactac
    24481 tttaatgatt taatgaaaga ttgattttga taagacaatt ctgatataat gtaaagtagt
    24541 tggcaaaaat agaaacatta aataaatttt ctttttaata atttaacttt taccttgtca
    24601 acaaggctat tttcggatag aatttcttag tacattattt cactaataca agaaggtaag
    24661 tatgttaaaa aacaagtcaa gactgcgagc tattttcgtt tttgttggga agatagcgtt
    24721 gttttacgtg attttgatgc tgctcgttta tttttttggt tacctagggc atggtcaaag
    24781 taattttatt tataatgaat tttaggagat tgtctgatgg ttaacgatat gattgaaaca
    24841 attgagtatt ttgcacaagc acaaccggat tttccagttt atgattgctt gggagagcgc
    24901 cgtagctatg ggcagctaaa ggaggactca gatagtattg cagcccttat tgagagctta
    24961 aagctaggtg aaaaatcacc tgttttagtt tttggggctc aaagctatga catgctggct
    25021 tcctttgtcg ccttgacaaa gacaggtcat gcttacattc ctgttgatgt tcattcggcg
    25081 ccagagcgtg tcttgtctat tattgagatt gctcagccaa gtcttatcat tgctattgag
    25141 gagctgccgg ttagtattga tgcgattagg gtggttagct tagcagagat agaggcagct
    25201 aaagcagcca aggcagcctt taccatgacc agtcctgtca agggagatga caattattat
    25261 attatcttca cctctggaac gacaggacag ccaaagggag tgcaaatttc gcatgccaat
    25321 cttttaagct ttaccaattg gatgattgag gatgctgagt ttgctattcc tgagagacca
    25381 cagatgctgg ctcagcctcc ttattccttt gatttgtcgg tgatgtattg ggcgccgacc
    25441 ttagctttag gtgggacatt gtttgcttta cccaaggaaa tggtttcaga ttttaagcgc
    25501 ttgtttagca caattgcgga gctgccgata gggatttgga cctcaacacc gtcctttgcc
    25561 gacatggcaa tgcttaatga tgatttttgt caggagaaga tgccaaggct gacccacttt
    25621 tattttgatg gggaggagct gacagtatca actgcaagaa agctatttga acgctttcca
    25681 gacgcacgca ttatcaatgc ctatggtcca acagaggcaa cggtggcgtt atcagcgatt
    25741 tcaatcacta aagatatgat agagacttac acacgcttgc cgataggcta tccaaagccg
    25801 gattcgccta cttatatcat tgatgaagct ggcaatgctc tggagccggg gcaacaggga
    25861 gagattattg taacgggtcc agcagtttct aagggttatc tcaacaatcc tgaaaagaca
    25921 gctgaagcct tctttacctt taatggcatg cctgcttatc atacgggaga tttaggatca
    25981 tttactgagg acaatgtgtt actttatggt ggacgattag actttcaaat caaatatgca
    26041 ggttaccgca tcgaattaga agatgtgtcg cagcagctaa accaatcacc gctggttgaa
    26101 tcagcagtag cagtaccaag gtataacaaa gagcataagg tccaaaatct cttagcttat
    26161 gttgtcttga aggacggggt gagggagcaa tttgcgagag atttggatat taccaaagcc
    26221 attaaagcct ctgttaagga tcatatgatg gcctatatga tgccgtctaa gtttatttat
    26281 cgtgaaaagc tcccattgac accaaatggc aaaatcgata tcaaattctt gattaacgag
    26341 gttaatcatc aatgacgacc ttgtttcatc acatacctta tatggagcct tatggcaatc
    26401 cgatttattt tgtctacctc atcattgctt ttcttccagt tattattggg atctttaagc
    26461 aaaggcgttt ttcgacgtat gaaagctttg tcagcctgat ctttattttg ctcatgtttg
    26521 gtggagagca ctatcagcaa ttgcttgcct ttttagccta tctaatttgg caaaccatca
    26581 gtgttttggc ttacaagcac tatcgtcaaa aggcaaatgc agcgtgggtt ttctatctta
    26641 gcattttagc cagtctattt cctttgattt gtgtgaaggt aagcctcagt ctaacgaggt
    26701 ctttctttag cttcttaggt atttcctatt taactttcaa aagcgttggg atgatcattg
    26761 aaatgcgtga tggggttttg acagatttta gtctaaagga ttttctacgc tttatgattt
    26821 tctttccgac tttttcaagc gggccgattg atcgcttcag aaggtttcaa gaggcttaca
    26881 ccaagcttcc tagtcgtgat gtttaccttg atatgctcaa taaggctgtc atgtatctca
    26941 tgctgggctt tctgtacaag catattatct cttattgctt gggtgggctg ctattgcccc
    27001 ttgctgaaaa taaggctctg actgtaggtg gctactttaa taaagagacg atctatgtca
    27061 tgtaccttta tgggcttaat ctcttttttg attttgctgg ctactcgatg tttgcgattg
    27121 ggttgtctta tttactgggg attaagacac ctgaaaattt caataagccc ttcttatcac
    27181 caaatttaaa agagttttgg aacagatggc atatgagcct atcattttgg tttagggatt
    27241 ttgtttttat gcgattggtc catctattga tcaagcacaa gacctttaag aatcgaaatg
    27301 tgacttcggg ctttgcttac ctgatcaaca tgctggtgat gggactttgg catggcttga
    27361 cgtggtatta tattgcttac ggtctgtttc atggtattgg cttgattgta aacgacgctt
    27421 ggcttcgtaa gaaaaaggaa atcaatcgtc gtcggaaaaa gcaagggctt aagcctttgt
    27481 ttgagggtaa ggtatttcat gctttatcaa tcgtggtcac tttccacgtt gtcttgttct
    27541 cacttctgtt attctcaggc ttcttaaatg agctttggtt tagcagaccg ttacgttaaa
    27601 aaaggagagt ataaaaatgt ctactaaaga aactgtaatt gacttatttg atcgcttgtt
    27661 tatggaagac gtatcagata tgatggacga ggatttgttt gatgctggcg ttcttgatag
    27721 cctaggaacg gttgagctga ttgtagagat cgaatctatc tttaacatta aggtgccaat
    27781 ttcagagttt ggacgtgagg actggaacac tgccaataaa attattcagg gcatagagga
    27841 attgcagcat gcttaaacgg ctttggttaa tcctaggtcc tctaatcatc gcttttggct
    27901 tggtttgtct taccatattc agctttccta ctaagcttag ctattcattg cgccaggaaa
    27961 agtcaaatgc agtggcaatc aatgatagct cctttaaaaa cggcttgatt aaaaggcagg
    28021 ccttgtcaga tcctaactac tgttttgttc cgttttttgg ctctagcgaa tggagtcgca
    28081 tggatagcat gcacccatca gtgcttgcag aacgctacaa gcgctcctac agaccgtttt
    28141 taattgggaa aagaggctct gcttccttat cacaatatta cggcatgcag cagatttcac
    28201 aggaaataac tggaaaaaag gcagtctttg tcgtgtcccc acaatggttt accccccaag
    28261 gcattgatcc tggtgcggtt caattgtatc tatctaatag tcaggtgatt gatttcctct
    28321 taaaagcaaa ggctagtcat aaggaatcac aatttgccgc taaaagaatg ctggacatta
    28381 atccgggagt tgctaaatca gagcttttaa ggaaaattag tcaaggcaag gccttgagta
    28441 gatgggacat tcgtctgctc aaatggcagc aggagctgtc cttaagagag gagtccttgt
    28501 ttagcttcct tggtcgttca acaaactatg aggataggat tttgcctcgt gttaaagggt
    28561 tgcctaaaac cttttcttat gagcgcttga gcgagctagc agccagacgg gctaaggaag
    28621 gaacttcaaa taatcgcttt ggcatcaaaa atgcttttta ttctaagcga attgcaccgc
    28681 aatttcctct ttataagaat tttcagtgcc gtaataatta cactgtgtca cctgagtaca
    28741 atgattttca gctggtattg tcagaatttg caaaacgtaa aacagaggtg cttttcgtta
    28801 ttacacctgt taatcaagcg tgggcaaatt atacaggctt aaaccagagg aggtatcaaa
    28861 aggctgtcag aaaaataaag catcagttaa cctcgcaggg ctttactcgc attgctgatt
    28921 tttccagaaa tggcggagac aagtatttta tggaggatac cattcacctt ggctggaatg
    28981 gctggctagc ctttgacaag gaggttgttc ctttcttaga ggatcaaaca ccaccatctg
    29041 aataccaact ggatccttac ttcctatcaa aggactgggc agatagaaca gcaggatttt
    29101 agggtcaata gaccattaga aaatgaggat tagaattgtt aatgagtatc atcgtcatat
    29161 tgcttatttt agccattgct gttttagtga ttgagtatgg tcaaaagcgg tccttttcta
    29221 gctggctgct tgaaaagatg tttgattatc gtaagtataa gctctctaaa aaggctgatg
    29281 actatgaagg aattgagacg caaagacgtc gtcgcattcc ctaccacttg gataatccag
    29341 aggcggtatt ggggattccc accacagaat atacgattga tggcatgcag gtttttgtga
    29401 tcaatgacca agattctcag gatcagccag tgatttacta tctttatggt agtgtctatt
    29461 tgcgtcgacc tgagacattt cactttaaaa ccattaagca tttgatccat ttaaccaatg
    29521 ccaagctggt gttcccaaat tttgagaagg cgccttatgt cacctataag gagatttacc
    29581 caaagcttgc taaaacttat caggagcttt gtctagccaa tggcgctgcc aaggttagca
    29641 ttattggtga ctcctcaggt ggtggcatgg ccttagcctt ggcgcaatac ctaagagata
    29701 cccaaactgc accacagcca aagcaattaa tcctgttatc tccttggtta gatgttagct
    29761 ttgctaatca ggattataag cattttgaag cagtagaggc ttatttagat gctaggcggc
    29821 ttcgagacat tggtgaattg tgggcaggca gtccagaaga aatgcggtct ccgtatgtca
    29881 gcccattata tggcgattat catgacctgc caaagattgt cacttttgtc gggacaaaag
    29941 agatttttta cccagatatt atgaccctgc atgagcgctt gatggagcaa gggcacttaa
    30001 atcagctcgt tattgctgag cagatgattc atgcttatgc gatcttcccg atacgagagg
    30061 caaggcaggc gcgcaagcag attgccgagc tgattttaaa gaaggagtga ttgttgctat
    30121 aggagtcagt tagccttgct tgtctgatga ggcttgggct tgagatttct agagaagctt
    30181 taaggccttt acttgggctg ttaatgctca ttaaagagga ttataggctt tatactaggg
    30241 cttaggattg ctgttttgct attcaataat attagtttag acttgattga ggaaaggcta
    30301 gttttagtta tggtcctcaa tctttttttg atggtaaaca tgtcaagaca gtttacttgc
    30361 tagggtaata atcctgtgct catttcatga gtggctattt ttatcctaag cttggtggtg
    30421 gaaaaatcag attaaaaaat atgaaatttg ctattgacag ctgtaagcga ttgcattata
    30481 ataaacttaa cttaaacgtt taagttaagt tgaataagct gatttgatca tgcactgcct
    30541 aaatgcaatc aataatctca aagcatttgg tgtagtctag taatcaatga ggcagtttat
    30601 tacggttata caatatttat ttagttcatc cctttaggag gtaaatagct atggcgtggg
    30661 attggaaaaa agcaggtgtt gttggagtag tgtcattggc ttcgatcatg gtattaagtg
    30721 cttgtagcgg aggacatcaa aaagaggcta agcaaaaaga cgacaatacc attgtagttt
    30781 cagttgatga gggctatgca gactacatca aagagattaa gacagccttt gaaaaggaca
    30841 ataaggtcaa ggtcaaggtc aaaaaggaag gtatgattga tacgctagat aagctatcta
    30901 ctgatggacc gacaggtgct tcaccagatg tctttttagc accatatgac cgggttggtg
    30961 ggcttggctc tgaagggcaa attgctgagg tgagcttagg caatgctgac cagtttgatg
    31021 acactgttaa aaagctagtc accataaatg gaaaggttta tggggcacca gatgttattg
    31081 agaccttagt gatgtattat aacaaggatt tggtatcaga ggctccgaaa acctttactg
    31141 acattgaaga gctaaataag gatcctaagt ttgcctttgc ttctgaagac ggtaagtctg
    31201 taggctttct tgctaagtgg acagacttct attatggcta tggcttgatt gcaggctatg
    31261 gggcttatgt atttggagat aagggaactg atccaaagga tttaggtatt ggtaatgctg
    31321 gtgccattga aggcttagac tatgctaaga aatggtatag cgtatggcct caaggcatgc
    31381 aggatactca aaaggctgga gattttatta cagagcaatt cacctctaaa aaggctggtg
    31441 tgattattga tggaccttgg gctgctgcct catttaagga ggctggtgta aactttggag
    31501 tggcacaaat tccaagctta cctaatggcg gtagctatca agcctttggt ggtggtaaag
    31561 catgggtgat ttcaaattat tctaagaata aaaagctggc acagcaattc cttgattatg
    31621 tgacaaatga gaaaaaccaa aaagcctttt atggtaagac acaagagatc cctgccaatc
    31681 tagctgctcg cagctatgct gcagaacaag gaaatgaatt gacaaaggcg gttattgggc
    31741 aattctcaaa tgctcagcca atgccaaata ttccagaaat ggcagaagtt tggggaccag
    31801 gtgcgaacat gttctttgag gtagcagcag gcaagaagac tcctgccaag gctgctaagg
    31861 aagcagctaa aaccattcaa gaggctattg cacaaaaata cactgaataa cataaaaagg
    31921 gaggctggga taaaggtatc ctagtctcca tcttgttacc tatagtatca gagtgggcga
    31981 tgaggagata ataataaaaa gtagtagtga ctagcttgtc ttgtttccca tcttgtccta
    32041 ataagagtat ctgataagac tgatgaacct agggaggaaa aaatgaacac agccggaata
    32101 ctgcatattc cagattctag atattgcttt gccttatcaa caaaggagct tgtgattcgg
    32161 ttgagggttg caaaggagga taacgatata gcggtgacgc tggtttatgg acctaagtat
    32221 cattatcatg agtatcaaaa agaactggcg atgtatgctg cttataccga tcatacccat
    32281 acctattatg aaatcacctt aagtcttgat gatgttagat tggcctatat ttttaagctt
    32341 gagcaatctg gtcacaccta ttactttagt gaggatggct tgaccacaag ctatgatttt
    32401 tcaaatggct tttacaactt ttttcaaatg ccttatatta atgctgtaga cgttcatcag
    32461 actgtccctt gggtgcacaa tgctgttttt tatcagatct ttgttgatcg ctttcatcgt
    32521 ggtgactttg aaaaggacga tagctatatt aatatggctt ggctggatag gccaactcct
    32581 aatagctttg ccggagggga tttgaagggg attacagata agctggaata ccttgaggat
    32641 cttggtatta atgtcattta cttgacaccg attttcaaat ccatcagtaa tcacaaatat
    32701 gatattagtg actactatgc tattgacccg atgtttggga catcgcttga tctccagcaa
    32761 ctaataaacg aggcccacca aagagggatt agaattattt tagatgctgt tttcaatcat
    32821 gctagcagtg attgcgagcc atttcaggac gttttggcac atggtagtgc ttcttcattt
    32881 tttgattggt ttatgattca aggagatcat ccttctgtag agctagctaa ttacgaaacc
    32941 ttcgctgatt gtcactacat gcctaagtgg aatacctcgc atcaggctgt tcaggattat
    33001 ttgattgaga ttggtcttta ttggatcaca gagtatcata ttgatggctg gcgattagat
    33061 gtttctgatg aggtatcgca tgatttttgg agacgctttc gaaaggctgt taaggcagtc
    33121 aaatcagatg cgatacttat tggagagaat tggcatgatg cttatcccta ccttcaagga
    33181 gaccagtatg atggtattat gaattacgcc tttaccaagg cttgtctcga ttattttgca
    33241 tttgatgcga ttagctcaca ggaaatggct gaaagattgt cgcatatttt aatgagaaat
    33301 acttggcagg tcaaccagat gaatctgaat ttactggatt cccatgatac gcatcgcttc
    33361 ttgactcagg tgaatggctc taaggacaaa ttattggctg gcttagccct tttagttacc
    33421 tttatgggca taccatgtat ttactatgga acagagcttg cgatggaggg aggttatgat
    33481 cctgactcta gacgtagctt taattgggac agcagcactt gggatatgag cttttggaat
    33541 caggttaagg acattatcag cctgcgtcgt catgcggtta tccaatttgg aagcatttcg
    33601 ataacctccc atgatgactg cctttgcgta aagcgtgaat taaacggtca atcgataaga
    33661 ttgctggtta ataatggcgt taagccatat cctattgaga aaggaggttc tgtgcttgtt
    33721 tctaatggtg tagataaaga gacatttgag ctactccaga acgggtttgt tgttagctat
    33781 taatatggcg ttttatcaaa ggaggttaag gatgaagcgt attactttaa catgtcgtaa
    33841 agcattaaca gtagctatgg cagcggttac cttagcaatg tcaactaaca gtgtctttgc
    33901 tattgaaaat actgcggtgt ctaataaggc tgatttttct actgacacga tttatcaaat
    33961 tgtcaccgat cgttttcatg atggtaatgc tgctaataat ggaaatacag atgtatttga
    34021 taaaaatgat cctaaaaaat atcatggggg tgattgggca ggtatcatta agaaactaga
    34081 agatggctac ttaaccaatt taggggtatc agctatctgg atttcatcac cagttgaaaa
    34141 cattgatacc attgaccctt caaatggcag tgcagcctat catggctact gggcaaagga
    34201 ttttttcaaa gcaaacagtc actttggaac aatggaggat tttaaaaagc tcattcaggt
    34261 ggcacatggc aaaaacatta aagtagttat tgattttgct cctaatcata cctcaacagc
    34321 agaatataat ggcttaacct tccctgagga cggtgcttta tataaggacg gccagctggt
    34381 tggtaaattc agtcatgatg atcaaaagat tttcaatcat gaatcatgga ctgatttttc
    34441 aacttatgaa aatagcattt atcattccat gtatggcttg gcagacttga acaatctgaa
    34501 tccaacagtt gacgattatc tcaaagaggc tattgataaa tggttagaaa tgggcattga
    34561 tggtattcgt gtagatgcgg tcaagcatat gtcacaaggc tggcaaaaaa attggttgag
    34621 tcatatctat gagaagcata atgtattcgc ctttggggaa tggtttgctg acggttcttt
    34681 taatgatcca ttgatgacta aatttgctga tactagcggc atgagcctgc ttgattttag
    34741 gtttgctaat tctgttaggc gcctgtattc tgatttatca gcgaaaatgc aagattttta
    34801 caatatgatt gtagctacgg aaaaagagta caaggaagtt tcagatcaag tgactttcat
    34861 tgataaccat gatatgaccc gctttgctac tctagtcaat cataatcaga cagctgttaa
    34921 tcaagcctat gctttactgc taacatcgcg tggtgttccg aatctttatt atggttcaga
    34981 gcagtatgct acaggtgcta acgaccctga aaatcgtggt gatatgccaa cctttgataa
    35041 gaattccact gcttatcagg tgattagcaa actagcacca ctgcgtaaga aaaatcaagc
    35101 cctggcttat ggtacaacac agcagcgctg gattaatgat caggtcttgg tctttgaaag
    35161 aaaatttgga aatgacgttg ctttagtggc tgttaataag gatcaaacaa atggctacac
    35221 aattagtggc gctaaaacgg ctttaccagc tggtaagtat gctgatgaat taggtggctt
    35281 actgggcgga aaggaattaa cggtatcagc tgatggtaat gttgaggcat ttgagttagg
    35341 tgcgggtcag gttgcagttt ggacctttaa agggcaacat gagacaccgc agataggaga
    35401 cgtagacgct tcgtttggcg ttgcaggaaa tactgtctct atttcagggc aaggatttgg
    35461 tagtgctcaa ggtcagcttc attttggtga tagcaaagca gatattgtgt catgggacga
    35521 taccttgatt caatttaaga tacctgctgt agctgctggg aaccatgata ttaaggtgac
    35581 cacatctaca ggacaaagca gtagccctta caaagccttt gaagtgttaa cagataagca
    35641 aattccagta agattggtgg tcaataattt caacactgta ttaggtgagc agctttatat
    35701 cgttggtgat gtggttgagc ttggggcaaa tgataatcat aaagctttag ggcctatttt
    35761 taatgcaaca cagtcaattg cgcagtaccc aaattggttc tatgatgtca atctgcctat
    35821 taacaaaacc attaactgtc atcttgtaaa gaaggatagt tctggtaaag tattgtggac
    35881 tagtccagaa acctatacca ttaaaactga tagcaaggct caaaccattt cattgaaaaa
    35941 atagttgcgt tatctgtgat gttatttaat actctatgaa ggaggagaac cataaaaggg
    36001 tgatagagag gaatgacaaa tgcttaagaa tgaaaaaatg aagaatccac aaaaagccat
    36061 gtggctttca ataatccctg gtctggggca actctacaat actcaaaagg taaaaggctt
    36121 tattttgctt cttgtgtttt taggtgagct gctagaggct ttctttgttg gtattccggc
    36181 tcttgctggc ttgtacagcc ttggtagtgt accaatggag gatcattccc tattcttatt
    36241 gattaaggga gctatgcagc ttatcctatt tgccttgttt ttgatctttc atttggctgc
    36301 tatgcgagat gctagactag tggcaaggga gatcaatgca ggccatagca tttcattaac
    36361 cttaaaggag atggtacaat ccatctatga aaagggcttt ccttatttgc tgattattcc
    36421 agcctacttg gccatggcct ttgccattgt ttttccggtg cttgttactt tattaattgc
    36481 atttacaaac tatgatttta ggcatattcc tccctataaa ttattagatt gggttggcat
    36541 taagaatttt aaaagcattt tagagcttag cacctttaag tcagcctttg gctctgtgct
    36601 gtcatggacc ttgatttgga ccttggcggc aacgagtctc cagattgtga taggaatagc
    36661 gactgctatt attgccaacc agtcctttgt gaagtgcagg cgcatttttg gggtgatttt
    36721 cttgctgcct tggggggtgc ctgcttttat ctcgatcatg agctttggta atttctttaa
    36781 tgattctatc ggtgctatga atgttcaggt cttaccattt ttagaaaagt ttgtgccatt
    36841 tgcagatttt gggattatcc catggaagac agatcctttt tggacaaagg ttgcggtgat
    36901 tatggttcag ggctggctgg gctttcctta tatttatatt ttggtgtctg gtattttaca
    36961 atcaattcct gctgatttgt atgaggcagc aacggttgat ggtgcaacag ccctgcagaa
    37021 gtttcgccaa attaccttgc caatgatctt tgctgtcgca gccccgacct taatctcgca
    37081 gtataccttt aattttaata acttctccat tatttatctc tttaataatg gaggtcctgg
    37141 tacagttggc ggtggcgcag ggtcgacaga tattttgatt tcttggattt acaagctgac
    37201 cacacaaacg tcaccacagt tttccattgc ttcagcggtg accttaatca tttccttgat
    37261 tgttatttct gtatcattga taacctttaa aaaattcaaa gcctttgaca tggaggatcg
    37321 ctaaatgggt aggaattatt tgccacagtc agtgaagaag aagcgcttgt tagctcagct
    37381 gttgacttac agctatttgc taatcctgtc gatcatcatc ttatttccaa tcttggtgac
    37441 cgttagctca gcctttaggc caggaaatac aactgccttt agctttcata ttgatgggcc
    37501 ttggacctta tcaaactttg agacactctt tcaggacacc tattacttaa gatggtactg
    37561 gaacacgtta gttgtcgcct ttttcacgat gctgatccag gtgacagtca ttacgctgac
    37621 aggctatgct tacagccgtt atcacttttt tgggcgtcaa aagagtttgg tctttttctt
    37681 agtggttcag atggttccga caatggctgc cttaacagct tattttgtga tggcttggtt
    37741 gtttaatgct ctgaatcact attggttcct cattctgatt tatgttggag gaggcattcc
    37801 gatgaatgct tggttgatga aggggtattt tgatactgtg ccttatgatt tagatgagtc
    37861 agctaagcta gatggctctg gtcactttag gaccttctac caaattgtat ttcctctggt
    37921 tcgtcctatg gttgctgttc aggccctatg ggcctttatg gggccatttg gtgactttat
    37981 gcttgctaag tttctcttgc gtgaacagga gcattacacc gtagcggtag gtcttcagtc
    38041 attcatcact aacgacgcta gggatcctaa ggtcacattg tttgcagccg gggccatttt
    38101 aattgcagtg ccaatttcag tgctattctt ctttttacag aagcattttg tttcaggctt
    38161 aaccaatggt ggaacaaagg gttaatttat ctttcaagga gcctttatca tgactaatga
    38221 tcgatttcct atttcttaca caaccattat tttttctcct aaaatgatat ttgctcgttg
    38281 cagtgccttt ttgtggtggc agaatgtgat tttagtgatc tttctaaatg ctctggtgtt
    38341 aatgccgatc acgctgcatt atgcaagctt gaagagctat cccttagagc acatagttag
    38401 taatggttta gactccttga cagaaaaaac ctatcatgcc ttgacacaag gcactatttg
    38461 gcatgatcgc tatgatggaa aaacagtcct tatagaggat actgatgctg ttgttgctgt
    38521 attgccaaca ccagaaatag tagaagagct aaagaaagat caaagaagcc agctgatatt
    38581 aacagaaacc tcatggattt taagctttcc tgatggtcaa aggctaactg ctaaggttaa
    38641 aggcaacaag gaaaggctaa cgcgcttaac ctctctagag gctgtcaagg cctttgttaa
    38701 tcagcaatgg tacaatagca atcgtgccgc tgtgcttgcc tttttgctgc tagtggctag
    38761 cagtgtggtc tatctaggag ccggtttagt gatcggaatt ggctcgttat cactgttatt
    38821 aacaagatct gctagattat tttcactcaa gagctactca gaatgcttgg gtttgctagt
    38881 gaattgcttt ggacttccta cgcttttagc agtgcttata agtttttggg tgcacaatcc
    38941 tattgttatc atgaatagtc aggtctttgg cacactgctc atgctggttc tagtctttta
    39001 caaaactcag tttagagatg aggagcaagc actagcttag cccttgctga catcaaaaaa
    39061 tccctccc
//
LOCUS       DARYMD010000018        36557 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYMD010000018 DARYMD010000000
VERSION     DARYMD010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36557
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..693
                     /locus_tag="TU818_000821"
     CDS             <1..693
                     /locus_tag="TU818_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923659.1"
                     /translation="TDDSFIAVFDPKLKEIDKHIFEDSVIASDFSVDGDDIYLLGTDV
                     KIKDNYPTYLYTLSIKNGQLAMKNKELLYEQPESTYFFHDSIVKEKQLYTALSGYRNN
                     VTKERTVLGQVFHYDMQSGQKHFFDLTEIAPVNIFDLGHDTLAIEHEKNEAGKIGFSL
                     FHLNDKTSTFIDLSQFGLSIESDYLKDVKQIDENTLLILAGHTLIGYHINDHQAIFNK
                     QVSDDAFHIWVK"
     gene            complement(1204..2832)
                     /locus_tag="TU818_000822"
     CDS             complement(1204..2832)
                     /locus_tag="TU818_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923660.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRRLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPFSSQALLNFWLPLLLVMLMLYGLVRRIMPAYYR
                     ETLYVGGKAKNAAVARKAAASDRQQSLQRLLTKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITDEYFGIALLVGVLLGSICTVPTSFVGVGISLEKDNFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYALIGLFVLGFHPVIVLSFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWIQRSFWKNLNKM"
     gene            complement(2837..3568)
                     /locus_tag="TU818_000823"
     CDS             complement(2837..3568)
                     /locus_tag="TU818_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923661.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYREVLVNGQLLSEHRNTIKRQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            complement(3605..3862)
                     /locus_tag="TU818_000824"
     CDS             complement(3605..3862)
                     /locus_tag="TU818_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0923662.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            4234..5709
                     /locus_tag="TU818_000825"
     CDS             4234..5709
                     /locus_tag="TU818_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0923663.1"
                     /translation="MINKRKKKLIYRYGVCSAAVILAALASLGTCKEAKALSGPPGYP
                     LTRDFSRNFLEENTAKYLDQLREHLQHRFSELESLTRKLEKEGGTRGPAGPPGPAGPK
                     GERGEPGPVGPMGPRGEQGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQG
                     PRGDKGDTGETGKQGPAGERGPAGPQGPRGDKGENGAPGEQGPIGPKGETGPKGDKGE
                     RGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGQRGEKGEQGPRGEK
                     GEQGPRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGPRGEKGEQG
                     PRGEKGEQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGE
                     NGEQQPKGDQGKDTKPSVPKAPESPKMPEKPQAPEKAPAPKAPKASEQSASPKAPAPQ
                     STPSKKAVLPATGEASHPFFSLAALSVIASAGLLTLKRKKS"
     gene            complement(5891..7879)
                     /gene="tkt"
                     /locus_tag="TU818_000826"
     CDS             complement(5891..7879)
                     /gene="tkt"
                     /locus_tag="TU818_000826"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL0923664.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSIEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGVANAVGMAMAEAHLAAKFNRPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(8263..8907)
                     /gene="fsa"
                     /locus_tag="TU818_000827"
     CDS             complement(8263..8907)
                     /gene="fsa"
                     /locus_tag="TU818_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL0923665.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGGHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            complement(9081..10586)
                     /gene="glpK"
                     /locus_tag="TU818_000828"
     CDS             complement(9081..10586)
                     /gene="glpK"
                     /locus_tag="TU818_000828"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL0923666.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNLVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWKDMETLKQLNATGQLFKASMSESRREKLYQGWKRAVKATQFFAEEL"
     gene            complement(10926..11519)
                     /locus_tag="TU818_000829"
     CDS             complement(10926..11519)
                     /locus_tag="TU818_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL0923667.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITEAPASAQAAGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD
                     GRVVYDIEFDAKDQEYSYTIDANSGDILEKSSEPVYD"
     gene            complement(12187..12387)
                     /locus_tag="TU818_000830"
     CDS             complement(12187..12387)
                     /locus_tag="TU818_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL0923668.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
     gene            complement(12446..12601)
                     /locus_tag="TU818_000831"
     CDS             complement(12446..12601)
                     /locus_tag="TU818_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL0923669.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGAALGFPVCGVACGS
                     IGVTGGF"
     gene            complement(13107..13973)
                     /gene="rsmI"
                     /locus_tag="TU818_000832"
     CDS             complement(13107..13973)
                     /gene="rsmI"
                     /locus_tag="TU818_000832"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL0923670.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLACYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPLKGECLLIVAGANQADASEPAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            complement(13978..14301)
                     /gene="yabA"
                     /locus_tag="TU818_000833"
     CDS             complement(13978..14301)
                     /gene="yabA"
                     /locus_tag="TU818_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL0923671.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            complement(14294..15094)
                     /locus_tag="TU818_000834"
     CDS             complement(14294..15094)
                     /locus_tag="TU818_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL0923672.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDYKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            complement(15091..15966)
                     /locus_tag="TU818_000835"
     CDS             complement(15091..15966)
                     /locus_tag="TU818_000835"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL0923673.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRACQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GRRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNQVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAANAQQLTAFSENTRLLELMAQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMALTLLTLILAKDYSRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            complement(15980..16615)
                     /locus_tag="TU818_000836"
     CDS             complement(15980..16615)
                     /locus_tag="TU818_000836"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL0923674.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            complement(16931..17215)
                     /locus_tag="TU818_000837"
     CDS             complement(16931..17215)
                     /locus_tag="TU818_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL0923675.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            complement(17216..17662)
                     /locus_tag="TU818_000838"
     CDS             complement(17216..17662)
                     /locus_tag="TU818_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL0923676.1"
                     /translation="MLIINEELFAIEKAIEQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKLCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            complement(17767..18357)
                     /locus_tag="TU818_000839"
     CDS             complement(17767..18357)
                     /locus_tag="TU818_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL0923677.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            complement(18588..19217)
                     /gene="upp"
                     /locus_tag="TU818_000840"
     CDS             complement(18588..19217)
                     /gene="upp"
                     /locus_tag="TU818_000840"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL0923678.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            complement(19367..20998)
                     /locus_tag="TU818_000841"
     CDS             complement(19367..20998)
                     /locus_tag="TU818_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL0923679.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLIFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLLDQWTFVNT
                     MTLFTSYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYIKKDMRAAA
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEGQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTLGLLVPIYLMY
                     RRLHQVTRFNRKLLHKRILLTVIETALMGLIVLLANWFLGYLFKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLLTRQLDKLIGSRAARYRQKLGL"
     gene            21084..22529
                     /locus_tag="TU818_000842"
     CDS             21084..22529
                     /locus_tag="TU818_000842"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL0923680.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDYQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQNKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGQHFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRIYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVVNSGMEHFNILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKVAGDYAIQLIGSFNQENAMAAGLACLRLGASLEDIRQGIAKTNVPGRMEV
                     LTMTNQAKVFVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVRIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQNEQDAL
                     IIAGKGADAYQIVKGQKTAYAGDLAIAKSYL"
     gene            22789..23568
                     /locus_tag="TU818_000843"
     CDS             22789..23568
                     /locus_tag="TU818_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923681.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKTLARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGQLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGHIK
                     YSGEVNQVMTPEMIQDIFQVKAQLVTDPLYHCPTLLTYQLI"
     gene            23593..24531
                     /locus_tag="TU818_000844"
     CDS             23593..24531
                     /locus_tag="TU818_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL0923682.1"
                     /translation="MKKLLLILTVFVTAFTLVACSSQSKQQESTSKASLSHKPKIAGV
                     TYYGDIPVKPKRVVSLAATYTGYLAKLDLHLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALEPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETD
                     QWLADWKQKTSDYEKEIKQVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQALHYD
                     APEKVKKEVFKQGYLSLSQEVLPDYIGDYVIVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSTGASQ"
     gene            24541..25566
                     /locus_tag="TU818_000845"
     CDS             24541..25566
                     /locus_tag="TU818_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL0923683.1"
                     /translation="MTAQHHTKPKLAKAAPPWLILTFISLTLVLAIYCSLRFGAVSLS
                     HQELYHILLGKQDQGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFSPHLHYSTIILLSLLGSLLATLLILSLAYQAGKGYTQMRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLALS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            25563..26561
                     /locus_tag="TU818_000846"
     CDS             25563..26561
                     /locus_tag="TU818_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL0923684.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILTACIGGGSLALSGLMLQSLTRNHLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIVLVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(26666..27319)
                     /locus_tag="TU818_000847"
     CDS             complement(26666..27319)
                     /locus_tag="TU818_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL0923685.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(27386..28321)
                     /locus_tag="TU818_000848"
     CDS             complement(27386..28321)
                     /locus_tag="TU818_000848"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL0923686.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGASHVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENRVDVPKDIAGMLLSGLISDTLLLKSPTT
                     HASDHRVAAELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFSFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            complement(28821..29612)
                     /gene="pflA"
                     /locus_tag="TU818_000849"
     CDS             complement(28821..29612)
                     /gene="pflA"
                     /locus_tag="TU818_000849"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL0923687.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            complement(29689..31023)
                     /locus_tag="TU818_000850"
     CDS             complement(29689..31023)
                     /locus_tag="TU818_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL0923688.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVISAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTDAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            complement(31151..31708)
                     /locus_tag="TU818_000851"
     CDS             complement(31151..31708)
                     /locus_tag="TU818_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0923689.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     SLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEELLDYIGQLNQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            complement(31718..32503)
                     /locus_tag="TU818_000852"
     CDS             complement(31718..32503)
                     /locus_tag="TU818_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL0923690.1"
                     /translation="MKQRLIAGEELSLPPVLKKLLQNSLVYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            complement(32516..33439)
                     /locus_tag="TU818_000853"
     CDS             complement(32516..33439)
                     /locus_tag="TU818_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL0923691.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDLEMERRNSWQGCKLKG"
     gene            complement(33630..34280)
                     /locus_tag="TU818_000854"
     CDS             complement(33630..34280)
                     /locus_tag="TU818_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL0923692.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLRLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVVVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            complement(34270..34848)
                     /locus_tag="TU818_000855"
     CDS             complement(34270..34848)
                     /locus_tag="TU818_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0923693.1"
                     /translation="MSKTHQLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQANLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     regulatory      complement(34921..35046)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(35700..35984)
                     /locus_tag="TU818_000856"
     CDS             complement(35700..35984)
                     /locus_tag="TU818_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923694.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     gene            complement(36004..36396)
                     /locus_tag="TU818_000857"
     CDS             complement(36004..36396)
                     /locus_tag="TU818_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923695.1"
                     /translation="MTALEKIRTAIRQKEEELEEQQEHYHQERLQMAAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
BASE COUNT        10664 a         8722 c         7266 g         9905 t
ORIGIN      
        1 accgacgata gttttattgc tgtttttgat cctaagctca aagaaattga taagcatatc
       61 tttgaggatt ctgtcattgc tagcgatttt tcagttgatg gagatgacat ttacctctta
      121 ggaacagatg tgaaaatcaa ggataactac ccaacctact tatatacgct atctatcaaa
      181 aatgggcaat tagctatgaa aaacaaagag ctgctctatg aacagcctga atccacttac
      241 tttttccatg atagcattgt caaagaaaag cagctctata ccgccttaag cggctatcga
      301 aacaatgtta ccaaggagag aaccgtttta gggcaggttt tccattatga tatgcagtca
      361 ggtcaaaaac attttttcga tctcactgag attgctccag tcaacatttt tgatttgggt
      421 cacgatacac tggcaataga gcatgagaaa aatgaagctg gaaaaattgg gtttagcctg
      481 tttcacctca atgataaaac gtctactttt attgacttat ctcaatttgg tttatccatt
      541 gaaagtgact acttaaaaga tgtcaaacaa attgacgaga acaccctatt aatattagct
      601 ggtcatacat taatcggata ccatatcaat gaccatcaag ctatctttaa caaacaagtg
      661 agtgatgatg cctttcatat atgggtaaaa tagctactca gttactgaaa acaacaaaag
      721 gtcaaagcac aagtccttga ctttttagtt aaaatagtta ggctagcttt ttctaagaag
      781 ctagcctaaa ttagtagtat ttggaactgc cattaagatg tgataaagcc agcatgcttg
      841 tgatgggtta tcagaatgtc acttcaatcc aaacgtcata aaagctcttt ttgaaaatgg
      901 tttagcacat gactgttgat ctaaagctag cagctgcaac agttgagtta gcttttttcg
      961 tgaggctccc aaagctatgt gtcgagcaac atcactaaca gctttaggag cttgatcttg
     1021 atgccccaca agctagcacc gtagggcact gctagcttgc taaagctttt tgctttcttt
     1081 tttcaatagc tgctctagct tttaacatat agttactgca attactctca ctatttgagc
     1141 tagaaccaaa acttcgtcac atcttacctt ggccaatctg gagaattaat accccagagc
     1201 tatttacatc ttattcagat ttttccaaaa gcttctttga atccagagct gggcaaagag
     1261 caaacagcta agaagaataa ggctcacagc aatgctcaca agaagaggct gctgactaat
     1321 ggtagcacac ataatcgcta aaacaatcaa aaagccacca acaattaagt cgccaaacat
     1381 cagcccaagc ataaaccatt ggctatttcc tctggtgaaa agctgggtga cgtcctgcca
     1441 tttcagatcc agcatgcggt aatcacgcct aaacatcaat tgcccttgta tgattcccat
     1501 caagacaaag cctaatgaaa aggataggac aataacgggg tgaaagccta atacaaacaa
     1561 tccaataaga gcataaacca ccaagggagc aaggatttgc agccctatca gcaagcgaaa
     1621 tttgttaagc aaaaagccct ttaagctaat gggtagggtc ttaataaagg tgaaattgtc
     1681 cttttcaaga gagatcccaa caccaacaaa gctggtcggc acagtacata tacttcccaa
     1741 gagcaccccc accaaaagcg caataccaaa gtactcatcg gtaatgtagc ttgaaaattg
     1801 tgcaccactt gtcacactag gagtgataaa gatcatcaca taaatcaaag gcatcagata
     1861 agtctgtgtc aatagtgtcg cattttgcag cgttgcaaga tggtgctttg tcaacaatcg
     1921 ctgtagactt tgctgacgat cagatgcagc cgccttgcgc gccactgctg catttttagc
     1981 ttttccacca acatagaggg tctctctgta ataagccggc atgatccgtc taacaagacc
     2041 atacagcatc agcatgacca aaagcaaggg aagccaaaaa ttaagcagag cctgactgga
     2101 aaacggtgcc acaacaacat catagctgcc cctaaaataa ggaatcaaag ggcgatctga
     2161 aaaggcttga tcagccatca ttcgctgatt gttagtcata ttgagaaata caatcaagcc
     2221 tagagcacca aaggtagaag caaacatcaa aaccgctgaa atcagcctgc gcttactact
     2281 cctcagaata atcctgccaa tccaagcatt gagatacaga gcaaaaacaa tcgagctgac
     2341 aaatagcacc acaaacagga taaacgctag cacaatcgcc aaagcatttc caatgatctg
     2401 ccagtaggca atcacgaaaa ggcttagcag cggcattaaa aatatggatc ccatacctaa
     2461 tgaggaaatc agcttagcaa tgaaaagctc ctcagatctt atcggcagat gaacatagag
     2521 cttaacgtca ttactctcat aaaagaccgc atacattgcc gtaaaggcat taacagttgc
     2581 cataacaaag aaaatagcaa tataaagtga caacagtccc ggatattggc taaaatcaac
     2641 acccataaac ataaagatgt aaatgactaa aaacagagca atcatcaagg cttgctgtct
     2701 gatcatactc ttgtaggcct tgaagttctc tttgggagcc ttttcttgct ttttctttaa
     2761 agctgtcagg gactgaggat tggaataaag gatattaatc ttgactaatt cccaaatagt
     2821 tgaccaattc ataccactat gcctcctgtg cttgacgtcc tgccaattca aggtaaatag
     2881 tctccagatc cttatcagga taatcagcct ttagctgctc aactgtccca acaaaaatca
     2941 atttcccctt tttcaaaatc ccaatccggt cacacagctg ctcagcaacc gacaagacat
     3001 gcgttgaaaa aagaaccgta ttaccagaag cagcatgctc tttcatcatt tcctttagat
     3061 caaatgaagc ctgaggatcc agtccagtca agggctcatc aaggatccag atactagggt
     3121 tggagatcaa agcaccaatc acaatgacct tttgacgcat accatgtgaa aagttatcaa
     3181 tcgtgttgtg catctcctgc gtcagctcaa ataactgcgt cagctcctca atccgagctt
     3241 tggtatccgc ctcactgacg ccataaatct tagcaagaaa ctgccaatat tcataggctg
     3301 tcaggtttaa gaaaatatcc ggtgaatcag gcacatagcc gatttgcctt ttaatggtgt
     3361 tacgatgctc actcagcagc tgaccattga ccaagacctc tctatagctt gcttcgataa
     3421 tagaggtcag gatactgatt gttgtcgtct tgccagcccc attgtgacca atgagaccaa
     3481 agatttcacc gtccttaatc gtgaggctta catcactcaa ggcctccttg tcaccgtata
     3541 gctttgaaac atgtctaaat tctatcataa ctctctccta tcctaaacca gacgctcgtg
     3601 ctggtcagcc tttttctaat aaataagcgt caagcgactg cttaaagcca cacaaggact
     3661 taggcaacaa caaatcattg gcctgtaagt aatcatcaag cgcttgattt agctgctctg
     3721 caatcgtcag cggattactg tttttgatta attggttaga agctgacagc aataatctgg
     3781 ctaaatggct attagcacga ttttctgggt aatcgtaggc ctgtttgatg acatcgtata
     3841 agcgctgctg ttccttttcc atagggcctc cctctaattt tgtacgttta cgctaataca
     3901 actagttaac acttcaatca taatctttat taggcttttt gtcaatatcc tatcgccata
     3961 tttgtctctt ttcacaaaag cagatatacc aacgatgatg gcgcttactt ttgttccttt
     4021 tttagggcaa tacgggcagt cagttgtgct tcttattttt agccataggt aacaaaatca
     4081 gacgataatc gttttcatta aaaaaaaaaa aaaacgaaac tacggagaca aactaatcag
     4141 cagctatttc ttacatttag ctagcgtgtt aagatagcta ttggaaaaga tttttaggaa
     4201 tacttcatat ttctatcatc aaaggagaga gaaatgataa ataaaagaaa gaaaaaactt
     4261 atctacaggt atggtgtctg ctcggcagca gttatcctag cagcgcttgc tagcctagga
     4321 acatgtaaag aagcaaaagc attatctggt ccgccaggat acccacttac tcgtgatttc
     4381 tcccgtaact tcctagaaga aaatactgca aaatatttag atcaattaag agaacatcta
     4441 cagcacagat ttagtgaact tgagagctta acaagaaaat tagagaaaga aggcggtacc
     4501 cgaggtccag cagggcctcc ggggccagcc ggacctaaag gggaacgtgg cgaaccaggg
     4561 cctgttggac ctatgggacc tagaggtgaa caaggtccta aaggcttaga cggagcacgt
     4621 gggcccgagg gacagcaagg aaaacctgga cctgtcggac ctcaagggcc ggcaggtcca
     4681 gcggggcaaa aaggggaaac cggacctcag ggacctcgtg gagataaggg cgatactgga
     4741 gaaactggaa agcaaggacc agcaggagaa cgtgggccag ctggacctca gggaccgcgc
     4801 ggagacaagg gtgaaaacgg tgcacccggt gagcaaggcc ctattggtcc aaaaggtgag
     4861 actggaccta aaggtgacaa gggagaacgc ggcgaaaagg gcgaccaagg tcaacgtggt
     4921 gaaaagggcg accaaggtca acgtggtgaa aagggcgacc aaggtcaacg cggtgaaaaa
     4981 ggcgagcaag gccaacgtgg tgaaaagggc gagcaaggcc aacgtggtga aaagggcgag
     5041 caagggccac gcggtgaaaa aggcgagcaa gggccacgcg gtgaaaaagg cgaccaaggt
     5101 caacgcggcg aaaaaggcga ccaaggtcaa cgtggtgaaa agggcgacca aggtcaacgc
     5161 ggtgaaaaag gcgagcaagg ccaacgtggt gaaaagggcg agcaagggcc acgcggtgaa
     5221 aaaggcgagc aagggccacg cggtgaaaaa ggcgagcaag gtcaacgcgg cgaaaaaggc
     5281 gaccaaggtc agcgcggtga aaaaggcgac caaggtcaac gtggcgaaaa aggcgaccaa
     5341 ggtcaacgcg gtgaaaaagg cgaccaaggt caacgtggcg aaaaaggcga gcaaggtcaa
     5401 cgcggtgaaa atggtgagca acagccaaag ggtgaccaag gaaaggatac caagccatca
     5461 gttccaaagg caccagaatc accaaaaatg ccagagaagc cacaggctcc tgaaaaggct
     5521 cctgcaccga aagctccaaa ggcttcagag cagtcagcta gccctaaggc accagcacct
     5581 cagtcaacac caagcaaaaa agcagtccta ccagctacag gagaggcaag ccatccattc
     5641 tttagtctgg cagctcttag cgtcatcgct agcgcaggtc tgctaaccct aaaaagaaag
     5701 aaaagctaag ccagctattt gacaatagct tctagcaact cgggatagat ctgcaaggct
     5761 gagcagtagc actattaaat ctgaaacaaa aacgcatgac gtcctcccta aaaagggttg
     5821 aacatcatgc gtttttttgt ctaataatgc cgaaagcaag cctagataag gcctgctcca
     5881 gcttaatcac ttatgataag gatttgtaca attcagtagc atgctctact gtaaagccat
     5941 attcttcaaa gatacgattg cccggtgcag aagctcccca tgtatcaatg gtcagtgttt
     6001 tccctgcaag gccaacgtat tttgcccagc caaagcttga gcctgcttca atagctagac
     6061 gttttgtcac tgctgctggt aggatttcct ccttgtagga agctggctgc tcatcaaaga
     6121 tattttgtga tggcattgat accacacgca catggatacc atctgctgca agagcggctt
     6181 gagtatccat tgctagcttg acttcagagc cggttgcaat gataatccca tcaaggtcac
     6241 cctttgcctc tgacaggata taagctccct tattaaggcc atcttctgcc aattccttag
     6301 taccttcaag tacaggaagg ttttgacgtg ttaagacaag cattgtcgga cggtctgtct
     6361 cagcgatcgc acgcttccaa gcagcgtttg tttcattgcc gtcagctgga cgaataacgt
     6421 tcagatttgg cattgatcga acactagcta gctgctcgat tggctcatgg gtcggaccat
     6481 cttcaccaac cgcgatagaa tcatgcgtca tgacataaac cgttggtagc tgctgcaagg
     6541 ctgccatacg aaccgctggc aataggtagt ttgaaaagac aaagaaggtt ccgccataaa
     6601 cacgtgttcc accatgaagg gcaataccgt tcatcgctgc tgccattgca aattcgcgta
     6661 cgccaaacca gatgttacga ccagcataat gacccggctg gaagtctgtc tcagccttaa
     6721 ccatggtatt gttagaggca gaaaggtcag ctgagcctcc ccagaaggct ggcacctgct
     6781 cagagatttg ttggatagcc tgctggctag aaacacgact ggctactgct gtgccaagct
     6841 cgtgagcttg caactcaacc tctgccgcct cattagcaaa ggcttttttg tattcggctg
     6901 ctaactcagg gtatgctgct tcataagctg caaataggtc attccatgcc tgctcagcct
     6961 gctcaccacg cgcctgaagg ccttgtctaa agcgctcagt cacctcttgc ggcacctcaa
     7021 aatcagcatg ggtccattga taagatttct tagcaaaggc aatgccttct gcaccaagcg
     7081 gagccccatg aacagctgaa gttccttgct tttcagcacc aaagccaatg attgtcttta
     7141 cttcaataat ggttggcttt tcagtctctg ccttagcttc ctcgatagct ttagcaatgg
     7201 cctctaggtc gttgccgtct ttaacaagga tatgctgcca gccgtaagct tcaaaacgcc
     7261 ccttgacgtc ttctgtgaag gccattgagg ttgggccatc aagcgaaata tcgtttgaat
     7321 catatagcaa gacaagctta ccaagcttca agtgacctgc cagactggct gcctcctgac
     7381 tgacaccctc cataaggtct ccgtcaccat ttagagcata ggtatagtgg tctacaatat
     7441 caaagccagg tctattgaac ttagctgcta agtgtgcctc tgccatagcc ataccaactg
     7501 cattggcaac tccttgtcct aaaggccctg tggttgcctc aacgccatct gtatgattga
     7561 cctctgggtg acctggtgtt ttagagcccc attgacggaa gttcttaaga tcctcaatag
     7621 acacatcata gcctgctagg tgcaacaggc tgtaaagcat ggcactacca tgacctgctg
     7681 ataggataaa gcggtctcta tttgaccaac ggcggcttgt ctttggattg actgtcataa
     7741 catgattcca tagcacataa gccatcggcg ccgcccccat cggcaaacct ggatgcccag
     7801 aatttgctgc ttgaatagcg tccattgata gagtacgaac agtattaact gccagctgat
     7861 caattgcatc aaatgtcata agtaaaacct ctctgtgtat tacaactaaa aattaaacgt
     7921 tttccattgt ctattgtaac ataaaagtaa actgattttt aacaaaatcc tataaagtcc
     7981 ttaaattctt atctagcaat aagcattgct gttcctagct ttttgtgatt gacagctgtc
     8041 ttagatagag cacctatgct cataagaaaa agcaagccta gctgttgcca gctaagcaag
     8101 cattcctctt tggtacctcc ctttggctac agtaagcgcc agctgcctgt taattctagc
     8161 gcaacagcaa agcaccagct gatcctgcca cctacaaata gctaatccca aactaaccgc
     8221 tacagccaca ttagaatata aggagagctc tatgctctta gcctattttt taaaggaagc
     8281 ccaatcctcc ataaaggtct ttaagccatt tgttgtcaat gggtgctcag tcatcttcgc
     8341 aaataatgga tctggaatgg ttgcaatgtg tccccctagc tgtgcaacag cttcaacatg
     8401 ggcagctgtc cgaatgctgg ctgcgatgat ttctgcttgg aagccataca aatcaatgat
     8461 cccacgcaaa tcactaataa gctgataagg atctgctcca atatcctcta agcgaccaat
     8521 aaatggactg atataggtcg caccagcctt catggccatt agtccctgac taactgtaaa
     8581 aataagcgtc acatttgttt tgatgccttc ttgtgacaag acattagttg cttttaagcc
     8641 ctctgtcgtc atcggaattt tcacgaccac attgtcatgc cacttggcaa tgttcctagc
     8701 ctctgcaatc atttcctctg cggttagtcc ggtgacctct gcactgatag ggccgtccac
     8761 aatctcacag atttccttga taactgtctc aaaatcacga ccctcacgcg agataatgct
     8821 agggtttgtg gtaacaccgt ccacaacacc aagctcatta atcgcacgaa ttgcctctac
     8881 atttgctgtg tctaagaaaa atttcatctt aacctccgtt aattagtctg ttatcagtca
     8941 ttgaacagca tgacgctgtt taccgtctac attatcatta taaaagtcac tcttaggata
     9001 taaaagacca agtatcacac agtctagtgt tcaaaactag acctagctat gggactctgt
     9061 ttctttaaaa ggcttgattc ttacagctcc tctgcaaaaa actgtgtggc tttgacagct
     9121 cttttccagc cttgatataa cttttctcgg cgagactcac tcatgcttgc tttaaacagc
     9181 tgacctgtag catttaattg ctttagcgtc tccatgtcct tccagtagcc tacagcaagc
     9241 ccggctaaaa aggctgctcc tagagctgtg gtttcaagat tttcagcacg agcaatatca
     9301 atccctaaaa tatctgcctg aaactgcatg agcatgttat tcatagccgc tccgccatca
     9361 acacgtaatt gctggatagt gatccctgag tccacctgca tggtatcaat cacatctctg
     9421 acctgataag caatagactg tagggtagcc ttaacaaaat cctcttttgt tgttccacgc
     9481 gttaagccaa atactgagcc gcgtgcattg gaatcccaat aaggagcgcc aagacctgta
     9541 aaggctggta caacatatac ctcatcagca ttggttgaag ccaaggctag ctgttcagac
     9601 tcaaaagagg tttttatcat tcgcaagcca tctcgtagcc attgcacagc agagccagca
     9661 ataaagatag acccttctaa ggcataataa accttgccat taataccata tccaatcgtt
     9721 gttagcaggt tgctgctgga taattgagcc tcttgaccag tattcatgat gataaaagag
     9781 cctgtgccat aggtattttt taccatacca ggctcaaagg ccagttgccc aaatagggct
     9841 gcctgctgat cacctgccat gccagcaata gctacctctc ctccgtaaaa atgaaaagaa
     9901 gccgttttac cataaatttc cgaattagac ctgacctcag gaagcatggc cttagggata
     9961 ttcagcaagg ccaatatctc atcgtcccat tttagctctt tgatattgta tagcatggta
    10021 cgtgctgcat tagaataatc cgtcacatgt accgccccgt ccgttagctt ccaaaccagc
    10081 caggtgtcaa tcgtgccaaa taataattct cccctttcag ctcgctcttg agcccccgga
    10141 acatgatcaa gaagccatct gagcttggtc gcagaaaaat aagcatctat aaccaggcct
    10201 gttttttcat ggatcatttt ggtatagcca tcacgcttta gctgctctgc aatggaggct
    10261 gtttgtctag attgccacac aatagcatta tagatgggca gacctgtctg tttgtcccag
    10321 actaccgttg tttcacgctg gttggtaatg cctatagctt ctatttgctc tggctttata
    10381 ccagactcga taaaggcgtc tgcaataaca gactgcacca aattccaaat gtgattggcg
    10441 ttgtgctcaa cccagccagc ctgtggaaaa agctgtggaa attccttttg actactaacc
    10501 agcgcttctc ctttcttatt gaaaataatg gcacgagagc tcgttgtgcc ctgatcaata
    10561 gccataatat aggtttcagt tcccatgtgt cctccattct atcgctgctg agataggctc
    10621 tctcaatcat agcaagcgct ttctactcta ttatacaaca tttacagccc atagcctatc
    10681 cttctagtca taaaagtatc actctgccaa atcctaagct gataatgcct atcatttcaa
    10741 ctaaacagcc cttatcacag ccaaatacca gcaacaaagg cgggctatag gctagcgcct
    10801 aaatggctgc caacaagctc cagctctatc aggcacaaca aggaacaaca aaaaacctaa
    10861 gcccttttag catataaagg cttaggaatg ttacaggctt ttatcacata agcggtgata
    10921 gctttttaat cgtaaacagg ctcagaggac ttttctaaaa tatctccact attagcatca
    10981 atagtatagc tgtactcctg atccttggcg tcaaactcaa tatcgtagac caccctaccg
    11041 tcgtctgttt ctttcgtcag ctttagcctt tgggcgtcag ctgctgtgat tgaggcgtcc
    11101 ttaaaagcaa gctccttggc cttgtcctct gaaatgccag ctgcttgatc agcctgacca
    11161 ccagctgctt gagctgaagc aggagcctca gtgattggct cagaggattt ttctaggatc
    11221 tcaccggtat tagcgtcaat ggtatagcta tactcctgat ccttagcatc aaactcaata
    11281 tcatagacca ctctaccatc gtctgtttct ttcgtcagct tgagcctttg agcgtcagct
    11341 gctgtgattg aggcgtcctt aaaggcaagt tccttggcct tgtcctctga aacacttgcc
    11401 ttcctatgat tctgagcact gccattttga cctagagcct gattctgttg acgacaagct
    11461 gataggctga ttaaggatag actcgtaaga gctattactg aaagtttttt gattatcatt
    11521 gtattgacct tccgtcttta ttcatcttat ttcctctagt atacattaaa taatctgatt
    11581 ttacaatttt aaagcgctaa aactctctta accaggctta ctcccttata tgataacccc
    11641 caaagagccc ataaggtaaa ggtaaggact ttgctatccc tcaaccaaga atagatcacc
    11701 cagccgaata aaaaaagcaa ttattggtag aatgagaaga attattttgg tcttatttat
    11761 tgccttcacc agctatcaat cactatttaa tgaccatttt ggtatgaacc ctcactgcca
    11821 ctcactatct gacaccaagc tacttttaag taccagcatc gatgtttctt acacctccag
    11881 tgcgtatcca tagccgacct tcagcattta ccagcatttc tgattgatta caaatactcc
    11941 ctaaactgtt gaaaaagtat ctaaacgaac catacaaaac ttaatttacc ttttttctat
    12001 ataaatagct aaaaaacata gtaaggtcac aagggatata agatttacat tgcttatagt
    12061 agtcgataag aaataaaaaa ttaaaaaaat aaagtaagaa gccccttctt tgcccctctt
    12121 agcactgtca accagtatat agataaaaat taaagcataa agacctgaaa aagtaatcaa
    12181 taacatctaa tttaccttat atgccaagca tgctcctaaa gcagtaaagc cgtctataca
    12241 tactcctttt agcaccggat gaggtatttt gcaaaatgta attcctgtct tgagacctcc
    12301 taatcccccg ataacagcat tacctgctgc atttcctcct gaaatatctt gcatttcact
    12361 tattgctaat gctctataat gttccatttc tattatcctc ctaaaacaag gttccaaact
    12421 cagaatcttt ctgtttttct catttctaaa agcctcctgt gacaccaata gatccacaag
    12481 ctactccaca tactggaaat ccaagtgctg cgcctgcact tcctgctcca atcacacctg
    12541 acacattggc agcccaatta ttttttcctc cttcaaagct agcaagcatt tctgtagcca
    12601 ttacgtcaaa ttattgtatt gattgcaaat actccctaaa aatcgatgtt gtccagttgc
    12661 aaccttgaca tatttagtat aacgcttttt ttgtaaaaca ttcctccata tcctaaacag
    12721 tcgttgaaac gtcctaaatg ggagcatttt tttcgtttaa gactgcaaag tgaccattaa
    12781 gggaaggcgt gaagcgacaa gcctgtggct ttaggaacct taaaaacatt aaaagcaagc
    12841 ttctcattgc tattaacaac acaaaaaaag caccagtctg gtcctcacta ggtactagtt
    12901 atcagtcacc cccctaaagt tgacaagaag ccaaaaaaag agaactgact agctctctta
    12961 gtgtgcagac aaatctatct gcttacatta atgacaattc tcagaagtgc aaaagacagc
    13021 tattagccct tacttgagta cctctccttt gcttggccta ctagagattc tctcaatcag
    13081 gcgactagtc cggattaaaa gccagtctag ccaagcccat gaaattgctg atagagctct
    13141 tggcgattca ccttatagtc tttggcgatt gtcttgatcg cctgattagg cttcatgcca
    13201 gcagcaatag cctgttgaac aagtgctagc agatccaaat cctcagcagg ctctgatgcg
    13261 tcagcttgat tggcacctgc cacaatcaat agacactcac ccttgagtgg atggtctgct
    13321 agataggtca agacctctga aatctgacca cgctggtatt cctcaaaaag cttggttaac
    13381 tctctcacca gcaccacctg gcgatcccca tagcaggcca gcaggtttgt tagcgtatcc
    13441 ttaacacgat aaggagattc ataaaagatt tgagtctctg gataatctgc cttagtcatc
    13501 aaaaatgccc tttgctgccc agcttttctt ggcaaaaagc cataaaacag atggggctgg
    13561 ggcgccaagc cactagcaat gaggccggta atgcccgcag aagcacccgg caaagcaaca
    13621 acagtaatat ctcgatcaat agctgctctg actagctcat gaccaggatc tgaaatagag
    13681 ggcataccag catcggagac ctgagccaat gaccttccag ccaacaacag gtccagcaaa
    13741 tctggaattt tatcataagc attatgctca tgaaagctta cctgctttgt ctttatccca
    13801 aaatgcttga gcaacagacc agtatttctc gtatcctctg cacagataat atccacctct
    13861 tttagaacat tgaccgctct aaaggtcata tcctctaggt taccaatagg ggtaggcacc
    13921 agatagagaa cccctgactc tttttcttcc ttgaagctct tttggatttg catgactcta
    13981 ctttctatct aatagctctc gacaaaacat acactcttca tcattttcac gacgttgccc
    14041 atagaaaaaa ttgcagatat gaaagccctc atcataaatg ccctccaagt ggtccttgcc
    14101 ctgcttagaa gaggtcttgg ccagattttc gtgctccaat tgactcaagc gctcacgtaa
    14161 tttggtgttt tcaagcctaa ggatagtatt ttcctctacg agtccttgga cctgcttttt
    14221 cattgcttca atttcagcta aagtcaccat caggttttgt gaaaagccat caaaagcgtc
    14281 aaacagttct tttttattca ctaactttaa cctcctctaa agcataggtt accaaggcca
    14341 gctggtcctt aaagcgaacc tgaatggtat ctgtaaaaag atcaattcct gcaacctcac
    14401 ctggtccctg cgctgttctt actatagtac cataatcagg aaattttttc ttactttctt
    14461 gataaaaatc gtcctcatat tgtaggcagc acagcaagcg accgcagcag cccaaagact
    14521 ttgccgaatg caaggacagc ccttgatgtt ttagcatttt gattgagact ggaggaaact
    14581 ctcctaaaaa gcttgaacag catagtgggc gaccacaggg acccagccct ccataaaccc
    14641 ttgcctcctc acgactatta atctgacgca gctcaatcct tgtcttgaaa taggcagcca
    14701 aatccttgag gagctggcga aaatcaacac gctcctgagc ggtaaaggta atcaaaacat
    14761 aacgtctctc aagggagaaa acaatgtcaa ccaaggtcat gtctaagcca tttctgtcaa
    14821 tcatctctgc tactttttgc tttgactggg ctgctagctg aaggttttgc tggtaagcct
    14881 tgtagtccat gtcattggca ggtctcaaaa cagagggcat atcctttggc aggtcgtcct
    14941 tacaaaagct ttttatcgga gaattgacca ctgccaatcg actgcccttg ccatcagata
    15001 tgacaagctt ggtttgcaca ggaaaggcct gatcggtttg aacgtacctg acagagcagg
    15061 tgtcacaata tttaattcca atcgtactta tcatgaaatc accatatatt ctaacgtatt
    15121 ttgaaagctg acattgcttt gccacataag tctagcctga taaacagcct ccagataggt
    15181 aaaagcattt tgtcgactgt agtccttcgc caagattaag gttaaaagag ttagtgccat
    15241 gtcctgctcc tctttttcct ctgctagctg aaccaagcga ttaagctcca gataagcctg
    15301 ttccttatcc tgaaaccaga tggaaacaaa acgctcagcc tgcgccatca gctccaacag
    15361 cctggtgttt tcagaaaaag cggtaagctg ctgggcattg gctgctaatc tggctaagag
    15421 gtctgcttga tgtttcaaaa gccccttttt ttgggccagc tcagagaggt agtgctcatc
    15481 ttttggaaag tgaaaaacct gtgtacggct cttgatcgtt ggtaggacct gattgtcatc
    15541 attcgttagt aaaaacatat agcaatcccc ttgtggctct tctatatatt ttaaaatgct
    15601 gttagctgca ttgacatgca tcttatcaca atccttaatg ataaaaacct gccgcctgcc
    15661 ctcatagccg gtctgcgaaa aatttgtcat catttctttg acggtatcag tcttgataag
    15721 ctgaccgaca ggctctaaga tggtgacatc tgaaaagtca ttgtgctcaa tcagctggca
    15781 agcacgacag tgatgacaag gagcattgcc tcttttttgt tcgcaaaaaa gagtcttggc
    15841 taaaaaaaga gccatgtcaa aattggcaaa atcacctgaa aagaggtagg catgatttag
    15901 acgttttttt tgcaaaatct cttgaaaggc ctgatagacc ctaggagcct tttgagccaa
    15961 atccattcct aacctcctgc tatgcttgac tgtgtgtgat aatggcagct aaagccgctg
    16021 acacaacgct ttctaagtcc tgtgatgcat caatcttgac aatacgctgg ggattttcca
    16081 aagccagctc cagatagccc ttacgaacac gctggtgcaa atctaattgc tcaagatcaa
    16141 gacgattgat ctctcgctca gtattttgtg caatccttgc caatccaagc tctgagggca
    16201 catcaaaata cagggttaaa tcagggtcaa caccatctgt tgcaaaatga ttgagccatt
    16261 gaatggcttg cttatccagc cctcttccgg cgccttgata agcaactgaa ctgtcaataa
    16321 aacgatccac caaaaccaag tgtcctgact caagagctgg catgatcttt tcaaccaaat
    16381 gctgccttct tgctgcaata tagagcagca gctctgtttt atcgtccatg gtcgtgtgac
    16441 tgacatctaa gatcagctga cgaatcttct cagcaatcgc aacgcctcca ggctctctcg
    16501 ttgttacaat ggtttgtcct agagctgcct gtaagagtgg caccagtctt tccagcaccg
    16561 ttgtttttcc tgctccgtct ggaccttcaa acgttattaa ttttcctcta gtcatcttta
    16621 ttcctttgtt tatcgttacc tctattttac caaaatttgc ctgaaaaagc actgccaatt
    16681 cattgggcag tgccagatca gaaaaaagcc tttttgtgct gccttttagg cgataggaat
    16741 aaaaagccag ccctcaaagc agcagcctaa gacttgtgcc tcacacctca aagcctatga
    16801 gcagccactc gataaatgac aatcgtctca gctcttattt tctttgccta agcaagccag
    16861 cagggctgat ccatcagctt tgagcaattg atgagctaag acatgctata taagacagga
    16921 tcaggcctac ttagccctgc tcaggtaggg cttgaggctc tagaggctca cgatgtaaat
    16981 tcccaacaaa atcacaatca atgtcatcaa aggctgatac cttcacctct ttgacaaatg
    17041 ttagccgact aatgtccttt agcttttctt ccatgtcctc tttattgatg taaataacaa
    17101 ggtatcgaga acgcctggaa tggtagtaca agtcaccata tttcatcact tttctagcgt
    17161 ctcgattgta atacaggtag ataaccagcc caattctctg ctgtttttga aacatttagg
    17221 tactcttttc ttttatattt tgatacggtc caagctcatg tcgaggtcta tttgtcgcca
    17281 agggaagtcc tgtgtcgaca agaatatcct cagacactgc ttctgcaata gctgtcgaaa
    17341 tcgtcgccaa aacctcctgc aaatcaacct gtgccaagcg cagatcagca accaatggat
    17401 gcaggtcaag ctggcgcttt tgatgaagta attggcagcg caacgctcta gcatctggac
    17461 acaacttaag caagtcctgc ctaagctcat aatcctgctt aagctcctca aataaggcta
    17521 actcggtctg tagggccaaa tctgcctcaa aagccttttt agccaaggca taggcctgat
    17581 actggctgct tgtcctaata tcctgaacca gctgctcaat agccttttca atggcaaaca
    17641 attcttcatt tatgattagc ataggttaat tataccataa ttttaaggaa gatagccctc
    17701 tttagcatgc aaaaagcccc tgaaacaatt tgtttcagaa gctgttaagc tattttacta
    17761 agctctctaa gctagctcat tattttccat gatttcatca ataaagccat aggctagggt
    17821 ttcttctgcg ctcatccaat aatcacgctc agcgtcctta tggatttgtt tgatcgtttt
    17881 accggcattt tgtgccaaaa tcttttccag gcggtgacgt gtctttaata aatgctcagc
    17941 agcaatggcc atatccgtct gctgcgtacc acctcctgtg cctcccatag gctggtgaat
    18001 catatattct gcatttggaa gcataaagcg cttgcccttt gcacctgatg aagcaataac
    18061 ggttcccata gaagcagcca tacccataac aatggtttgc acatctgcct taataaagtt
    18121 catcgtatca acaatagcta aaccagctga tacagagcct cctggggtat tcacatagag
    18181 gtaaatatct tttgtgttgt cttgggcatc taaaaacaag agctgcgcaa taacagagtt
    18241 tgccatatta tcctctactg gaccagtcag catgataata cggtccttta acagacgtga
    18301 ataaatgtca taagaacgct ctccacgact ggtttgttca ataactacag gaatcataaa
    18361 aatctccaat ctatcgtgac tgtctaacac cactctgcct catgcagtga caggcagtca
    18421 aacacatctt tttataatga ttgaccttat tataatctct tggtcaaaaa aggtcaaatg
    18481 ataaacttgc ttttaaaaac cttccagcct aaactagaaa gtcttattag ctttagcagg
    18541 ctagcctcta gcaagcagag cctagcacaa ccaaagcctg tagcctttta cttggtacca
    18601 aataagcgat caccagcatc tccaagacca ggaacaatgt agccatgatc atttaatctt
    18661 tcatcaaggg ctgcggtata aatgtcaaca tctgggtgag cctcctgaag ctttttaacc
    18721 ccttctggtg ctgctaccag acacacaaac ttaatattag cagccccacg ctttttcagt
    18781 gaatccactg caagaatagc agagccgcca gtagccagca tcggatcaac aataaaaatt
    18841 tggcgctgat caatatcctc tggcagcttc accaaatatt caaccggctc caaggtctcc
    18901 tcgttacgat acataccgat gtgaccaacc ttggcagctg gcacaagact aagaaagcca
    18961 tccaccatac caataccagc tctaagaatc ggaacaattg ctaatttttt acctgctaac
    19021 tgcttttgaa ccgtcttggc aaccggtgtt tgaatctcaa catcctctaa tggcaagtca
    19081 cgagaaacct cgtagcccat aagcattgca atttcattga ccagctctct aaaatccttg
    19141 gttgaggtat cctgacgacg caggattgat agcttatgct gaataagtgg atgcgaaata
    19201 acctgacatt ttcccatgat gacgtacttc cttctttatt ttttacactt ttgctattat
    19261 accaaaaaat tgaaaacctt gcttactttt ttcagatccg gttgaaatga taaaagcaag
    19321 aatctgatca gctagctgcc tgcttcagct gccttgatct tgggtgtcaa agtcccaatt
    19381 tttggcgata cctagctgct ctgctgccaa ttaatttgtc cagctgacgc gtcaataacg
    19441 tcatgtaggc gtaaacaccc attcccaagc caccaataat cactaagtaa agcaggctag
    19501 tcaatctgcc tgtcggctta aacaaatagc ccaaaaacca gttagctagt agcacaatca
    19561 ggcccatcaa tgctgtctca atcaccgtta gtaatatacg cttatgcagc agcttacggt
    19621 taaatcgtgt gacctgatgt agacgacggt acatgagata gataggcact agcaagccaa
    19681 gggtcgtagc taacaaagga ccataagcat gaaacagata gatcaaagga acctgcaaaa
    19741 ccagcttgac aaaaacacca taagcaaaat aatagatggc cttacggttt tcaaacaggg
    19801 cctgcagcat cggagaaaaa agcgtataca aggccatcaa tagggtaagg caaagcacag
    19861 caacaaacag cctaacagcc tgtccctcgc tactaccgta aaaaaccgta taaagaggcc
    19921 ttgccagtat aatagctcct gtcagagcag gcaataaaaa catcagcagc atttcaatgt
    19981 tgttaatgat caggcgcgct gctgctcgca tgtccttttt aatgtaattt tctgtcaata
    20041 aggcaatacc aacactacca attgaagcgg ctactgcaat gagcaccatg gtgattttag
    20101 cagggttggc gttaaaatac ccaaacagca cccagagctg agaacgcgtg tagctggtaa
    20161 acagagtcat cgtattgaca aaggtccact gatcaaggag ctgaaaggcc tgaatcgcac
    20221 ttcctgtaat aataaaggga atcgactcct ttaacgtttc aataagcaag cccttgatgt
    20281 caataggaat cgcatgctct gtcttggtaa aaatagcctt taaaaggccc tgcgtccaga
    20341 aataataaaa gagcaccgcc atactggcta tcattccaat aaaagcagca aaggtggact
    20401 gcgtaacagc tgcaatatag tccttagacc ccattttcat gatgaaaaag gttgttagaa
    20461 gcatccagat cacacgaacc agctgctcag caatttggct aagagcatag ggcttaatct
    20521 ccttatagcc ctgaaaaatc cccctaatca cgctcatcac tggaaaaaca aaaacagcta
    20581 atgataagct atgcataatc gggacaaggg tctcatcacc accggacaag cgagcaaaga
    20641 gcggagatcc cagatacatc agcactgaga aaatcaagcc taataccagc ataaccttta
    20701 gagtgcttcg aatgagctga tagctatgct cttgctgtcc catcgagttg tacttagcga
    20761 cctgcttagc aatggcaaca tttagccctg ttgtcgaaat caacaaaaaa taggcataca
    20821 cattgtatcc catattaaag agcgcatttg cctgtatcgc atactgcccc atccatatgt
    20881 accatggaat aatatataga acgcctaaaa gtcggctaat aaaattacct gcggtggacc
    20941 aggctgctcc ctgaaccatc agctgttctt gtgtcaattg ttttttttct gtcgacatat
    21001 ccgttcttcc tagtttttat agctttatta taaacttttg cttgtgactt gtaaaacaag
    21061 aacattaagg ataaaataag gctatgataa caattgagca cttattaacc attttaaaaa
    21121 aggaccataa tttccgagag gttcttgatc aagacggcta ccactttaac tatagcggtc
    21181 tacagtttga cagccttagc tacgacagca gacaagcaga tgagcagacg ctcttttttg
    21241 ctaagggatc agcttttaag gctgactttt tgagacaggc cattgccaag ggactaagac
    21301 tctatgtttc agagattgac tatcaggtag ggatccctgt tattcttgtt aacaatatta
    21361 agcacgctat gagcctagct gcgatggcct tttatgatta cccacaaaat aagctcaagc
    21421 tattagcctt caccggaaca aagggcaaga caactgctgc ctactttgcc tatcatatgc
    21481 taaaggaatc tcataagcct gccctgctct ctacaatgaa cacgacctta gatggccaac
    21541 acttttttaa atcgcagtta accacacctg aaagtcttga tttatttgcg atgatggctc
    21601 agtgtgtggc taatggcatg acgcatttgg tgatggaggt ctctagtcaa gcctacttgg
    21661 tcgggcgtat ctacggctta acctttgatg tcggtgtctt tcttaatatt agccccgatc
    21721 acatcggacc aatcgagcac ccaagctttg aggattattt ttaccataag cggctcttaa
    21781 tggaaaatag ccgagctgtt gtggtcaata gcggtatgga gcattttaat atcctagcag
    21841 agcaggtggc tgataagcct catgattttt atggcaaagg ggcttgcaat aggctgctgc
    21901 agcggcaggc cttctcattt caagcagccg gcaaggtagc tggagactat gcgattcaat
    21961 taattggcag cttcaatcaa gaaaatgcta tggctgctgg actagcctgt cttcgactgg
    22021 gggcaagcct agaggatatc cgccaaggca ttgctaagac aaacgtccct ggccgcatgg
    22081 aggtcttaac catgaccaat caggccaagg tatttgttga ttatgcacat aacggtgata
    22141 gccttgaaaa gctcctatct gttgtcgaag agtaccagaa aggccagatt tacttgattc
    22201 taggagcacc gggcaataaa ggcgagagcc gtcgggctga ttttgggcaa gtcatcaacc
    22261 agcaccccaa tgttcgtatt attctgactg ctgatgatcc taattttgag gacccacagc
    22321 tgatttcaga ggagattgct agctatattc accgcgaggt tgatattatc attgaccgta
    22381 aagaagcaat caagactggt atggagcgct gtcagaatga gcaggatgca ctcattattg
    22441 ctggcaaggg ggctgatgct tatcagattg tcaagggaca aaagactgcc tatgcaggtg
    22501 atttagcgat tgcaaagagc tacctataga ctggtctaac aggctaaaca gtaataattc
    22561 ttaagattac tgataatgat tctaagctgg ctcctttttt agcataaact cagtaattag
    22621 attctgaaag gcttttttag gccttttttc tatgctataa tgggatagct tttaagagaa
    22681 agcgcactat tatagtcaga ccaaaaaagc gactagcatt tcataggcta tcagcccctt
    22741 agaattttgc tagctggctt tgcttgacta ttagaaagga gaaaaaccat gtcaacaatc
    22801 agtgctgaga ggatttcagc tggctatgat caatcgctta tcatcagcaa cttatctgtc
    22861 actattcccg aaggaaaggt aacaaccatc atcggtgcta atggctgtgg gaagtcaacc
    22921 cttttaaaga ctctggcacg actattgcca ctcaaagcag ggcaggttct cttagatgga
    22981 caagccattg ctagactagc aaccaaggac gttgccagaa cactagcagt tttacctcag
    23041 ctgcaagaag ctactacagc tactgtctat gagctggttt cttatgggcg ttatccccac
    23101 caatcctacc taggacaact cagtcaagct gataaggata agatttgctg ggcaatggag
    23161 gtcacaagca tggcacccta tgctcatcag gctgttgatg ccctgtcagg cggccaacgt
    23221 caaagggcct ggattgctat ggccttagca caggatactg atattatttt tctagatgag
    23281 ccaacaacct acttagatat gaatcatcag ctcgatattt tagaattact aaaggagctc
    23341 aatcaggtct ctggaaaaac aatcgtgatg gtccttcatg atttaaatct ttcagcacgc
    23401 tactcggatc atctgatcgc catgaaaaat ggacatatca aatattctgg agaggtcaac
    23461 caggtgatga cgccagagat gattcaagac atttttcaag taaaggctca gctcgtcact
    23521 gatcctctct atcattgccc tacattgctg acctatcagc tgatataaat ttattctagg
    23581 agaatagaat acatgaaaaa actactgctt attttaactg tttttgtgac agcttttaca
    23641 ttagtcgcct gctcaagtca aagcaagcaa caagaaagca ccagcaaagc aagcctatcc
    23701 cacaagccaa aaattgctgg agtgacctat tatggtgaca ttcctgtcaa gccaaagcgc
    23761 gtggttagct tagcagctac atatactggt tacttggcaa aattagacct tcatctggtc
    23821 ggtgtcacct cctacgacaa aaagaaccct gttttaacaa aaagcattac tcaagccaag
    23881 caggtggcag ctactgacct agaggctatt acagcactag agcctgatct cattgttgtt
    23941 ggctcaacag aagaaaacat tgaccagcta gcaaaaatcg caccactaat ctccattgaa
    24001 taccgcaagc gtgattattt gcaggtgttt tctgattttg gccgtatttt taacaaggaa
    24061 aaggaaactg accaatggtt ggccgactgg aaacaaaaaa caagtgacta tgaaaaagaa
    24121 ataaaacaag tcaccggatc agctgctacc tttacaatca tggggctcta tgaaaaggaa
    24181 atttaccttt ttggtaagga ctggggaaga ggtggtgaaa ttattcatca ggccttacat
    24241 tatgatgctc ccgaaaaggt gaaaaaagag gtgtttaagc agggctatct gtccttatca
    24301 caggaggttc taccagatta tattggtgat tatgtgattg ttgctgctga ggatgaccaa
    24361 accggctcag ccttatatga gagcgacctt tggcagcaga tccctgctgt gaccaacaat
    24421 catgtcatca aggtcaacgc taatgtcttt tacttcacag acccactgtc actggagcac
    24481 cagcttgagg ttctaaaaaa ggctatcctc tcaactggtg caagtcaata aaaacttaag
    24541 atgacagctc aacatcatac taagcctaaa ctagctaaag cagctcctcc ttggctgatc
    24601 ttaaccttta tcagcttaac tctagtgctt gccatttact gcagtctgag gtttggggct
    24661 gtgtcactat cacatcagga gctctatcat attctacttg gaaagcagga ccagggtcaa
    24721 aaggccagca ttattttgga cattcgcctg ccccgcttga ttttagcagc tctagttggt
    24781 gctgcacttg ctgtttcagg agctatcatg caaggcatta ccagaaatcc cattgccgag
    24841 cctggcttac tgggaatcaa ctctggagct gggctggcat tagtcatcgg ctatgctttt
    24901 tcccctcatc ttcattattc gacaattata ttactttcct tgctagggtc actcttagcg
    24961 accctattaa ttctcagcct agcctatcaa gctggtaagg gctacactca aatgaggctt
    25021 attttagcag gagcgatgat atctatgcta ctgtcagcta tcggacaagg aataacaact
    25081 tattgtcacc tagccaatgc cattattggc tggcaggcgg gaggattgat cggggtcaat
    25141 tggcagatgg ttagctatgt tgcgccactc atcatctgtg gcttagccct atcttatctg
    25201 ctagcctatc atttgaccat tttaagctta agtcaagagc aggccaaggc cctagggcaa
    25261 cgcaccttct tgattagcct tatctttatt ggacttgtgc tgcttctgtc ttctgctgct
    25321 gtagcagtag ccggcagcat ttcctttgtc ggcttgatta tccctcatgc catcacatta
    25381 gtcactgcta aggattaccg ctggatcctg ccgctagcta ctcttcttgg agccagcttt
    25441 atgctttggg tagactttgc ctgtcggaat atcaatcccc cctatgaaac accgctatct
    25501 gctttgatca gctttattgg gctgccctgc tttttatggc tagttagaaa aggaggtcgc
    25561 ttttgacagc tactaaaaga cacgtcccat tatttctagg actaatctct ggactggtct
    25621 gtttgatgat tatttccttg tctattgggg aatctagcat gtcaccattg gaggtcgtca
    25681 gggtgctttt tggtaaatcc actgctgata tggccttgat catcaccaac attagactcc
    25741 caagaatttt aactgcctgt atcggtggcg gctcactggc cctttctggc ttaatgctgc
    25801 aaagcttaac gcgaaatcat ctggcagatt ctggcatact aggcattaat gctggtgctg
    25861 gtatggctat tacccttgtc atatcctaca gcactagtaa cagtctgacc agcaggcaag
    25921 ggctgccgct tatgaccata tccggggcaa tggcaaccat tgtcttggtc tacctgctct
    25981 cacttcgtca tggccatatt gatcctattc ggctgattgt cactggcgta gggctatcaa
    26041 ccatgctatc tagcctgatg attgcctttg tcggcaatgt gaaccgttat aaggtggatt
    26101 atgtgattca ttggctaagc gggcagctaa caggcgatga ttggtccaag ctaagcattg
    26161 ttgctccctt attggggatc acttggctgc tagcctttag tcaagcctat aagctcaaca
    26221 tcatggcatt aaatgatgaa gcaagcatgg ctctaggctt caagctccat cagtaccgta
    26281 ccattgttct tgcactatct gcgattctct cagccctaag tgttattttg gtcggaaaca
    26341 tcacctttat tggtctgata gcaggccata ccagcaaacg actagtggga gctgatcacc
    26401 gattaagcct gcctgtcagc cttttcatcg gcatgattct gcttctcttg gctgacacta
    26461 tcggacgagt ctatctcgtc ggcagcaata taccaaccgg tattcttgtc tcaattattg
    26521 gtgcatccta ttttctctat ctgatggtca aaatgacata agagcctctg ctgcatagct
    26581 taaagggctc agcaagcata aatggcttag actcaactgt tttacagtgt gggtctaagc
    26641 cattttttat tcatcaagtc aactcttaat cagcgtagaa aatcagctgc tccttatcaa
    26701 aagccagctt caggcagtat ttagtggcct ctactttttc aatatagcct agaagctcca
    26761 aggcattcac aaaaatatct gtccgctttt gcataacaat ctcttttcta gcaaatttta
    26821 gaagaaagct ggtcatgtac ttcaaggcat agtcctgatt cacatcacct aatagggcat
    26881 agagccttaa ttgctcatca gatagggctt cccctcttct taagcggtaa aaataattgg
    26941 caagcgtcag cttatctcgg tcaatggttg ttttttcctt gatcaaaacc tgattggtct
    27001 gattagacag cactgtctca aacaccaagg ccatcaaagc ttcatataga tctgatgccc
    27061 tatccacaaa gattagatct tctaatgtca cctgctgcag gtcatctagc aagggcagac
    27121 acagatagta gcgtctgttt tttcgacaga tatagccagc ctgaatgtaa gcttcaagcg
    27181 ccttatcaat ccccttaaca tgagaaaagg cctgcttaat gtgacgcagg gttacgtcat
    27241 catgctgatt gaggtaatga ataaggtctt gaaaaaaagg ctgacgcgtt aatttatcag
    27301 ggttaaaaat ggtaatcata ctactattat agcaaaaaga ccaaagggct gctgataaaa
    27361 atcaacaccc ctctacaggc aagctctatg ctccaaagct ttcagttaat tgagggacaa
    27421 cctgcttttt acgagataca gcacctgcta ggaaagcatg attatcctca agcttaaagc
    27481 taaaggctgc ctcaacctta tccatattcg caccaagcgc caaaatctct gaatttgaat
    27541 taacaatatc tgtaatcatc aagacaaaat cagaatagcc ctcacttgcc atcacctctc
    27601 taatagcggc ctcaatagcc tccttgcgct ctaacacctc tgcaatgtca acggtattga
    27661 cctgggctac acgaactgcg ttgccattta attcaaaggt cttagcatca atatcaatca
    27721 attctgcttc tgatttactt gcaaggtttg ttccggcctt tagcatagcc ataccgtatt
    27781 cctctagctt aactcctgct aactctgcta attccgcagc aacacgatga tctgaagcat
    27841 gcgttgttgg tgattttaac agcaaggtat cagaaatcaa gccagacaaa agcatgcctg
    27901 caatgtcctt tggcacatca accctatttt ccttgaacag gcggtaaaca atagatgagg
    27961 cagagccaac aggttcgaca cgcatataaa gcggatttgc tgtctcaaaa ttagccaccc
    28021 gatggtggtc aacaatacca tacacctcaa cctcacgaat atccgaaata gactgtggaa
    28081 attcgttatg gtctgttaga ataacatgac tagcaccctc tgcttttgct gatgtcacca
    28141 ctcttggtgc tgatacccca aaatagtcaa gggcaaaggc tgtttcttca tttgggtcac
    28201 ccagagcgac tacctccgta tccaaatcaa aggctttttt tgctaagtag tcaaaagcat
    28261 acgatgatgc gatggcatca gtatctggat tttgatgacc aaaaactaat agttttgaca
    28321 taaagtttct acctcattct ctttattcat cttattgtag cagaaatagg ctctaaaatc
    28381 aaagaagatt ccccagtcac aggccaagag tctaaagggc ataagggcac agaatctcag
    28441 gtattaaaga gtcctgtcaa acacacaaga acaggcaagc cagtccaaaa agcaatgcct
    28501 tctataatga gctattcagc tatttgggga caatacactg tccttgattg gtttaatgct
    28561 tcaaggatta ctttttggca cgtgtctgag ctcgcttaaa aacactgaag gtctcatcaa
    28621 gccagccgct tcatcagcaa aaaaacggct ctataatttc catggtggat ttacccacta
    28681 cagaaattat agagcccatt tacctcgctt tgcacatcac acaagagaaa acgagcttcg
    28741 tctcgtgctt agttatcagt cacccactac agttgacatg gggccaaaaa aagctgggca
    28801 tttcccaact ctagcttagc ctatgattga tgaatacggt tcatgtattc agtataggat
    28861 tctgtatgca gcagcttttt ggcattctcc acccgctcct tggttggtgg cttaacgccc
    28921 tcaagctggt atggaatccc taactcgcgc catttgaact ctcccatcgt atgataaggg
    28981 agtacctcaa acttgtcgac atttctcaag gtcttgacaa acgcatctaa gcgtaccaag
    29041 tgatcatcaa tgtctgtcaa gccaggcacc aagacatggc gaatccagac gggcacctgc
    29101 ctatcagaga ggtagcgagc aaactgcagg atatttttat tgggctgacg ggtgacaagc
    29161 ttatgctgct cctcgtcaat ctcctttaag tccagcaaaa tcaaatcagt aactgctaat
    29221 aatgtttcta acagctcatg gtattcaggg gttggacgat aggcaaagcc acaggtatct
    29281 agcgttgtat ggatacctag ctttttggcc tcagtaaaga gcgcagtgat aaagtccatt
    29341 tgcagcatag cctcaccacc tgacacagtg attccaccct ttttccccca aaagtgccta
    29401 tattgcagag cctcctttag gacatcatta acggttcggc gttgagattg attggtttcc
    29461 atagcccagg tgtccggatt atggcaatac tggcaacgca tcttgcagcc ctgcaaaaaa
    29521 atgataaaac gtatccccgg accatcaaca gaaccaaagc tttctgtaga atgcaccatt
    29581 ccagttactt gcccataatc tacttcaacc attgtgtctc cttcaccctt gtaaatggtt
    29641 ttacgttttc attatatcat gtttcatcaa aaagactaag ctcaatgcct agtcttcagt
    29701 aatattctgt tctatattag aaatagtaag tttcaatttg gtgatacgac cgtcctttac
    29761 tttgtcattg accaaaacca gatgcttttg cttgctatca caggcaaagc tctctttctc
    29821 cttttgactt ggaatggtac caatccctgt caaataaaag cccgcgatgg tatcgacatc
    29881 atcactttct aattctgtgt caaaatactc gttaaagtcg ttgagcgtca ttgtccctgt
    29941 gacaatatag gtgttgtcat caatgtgatg aacaaattgc tcagccttgt ctgtctcatc
    30001 atcaatctca ccaacgattt cctcaagcaa atcctcaagc gtcaccaaac ctgcaacccc
    30061 tccgtactca tcaagtagga tagccatctg gttttgagta tttcgcaatt gcctcaacaa
    30121 atcatctaca aaaatcgttt ctggtacaaa gagcggctcc tgcagaagct ttctcatgct
    30181 gatgttttca aagccctgac gaaagcctga ttctaaaagc cttttggtat gaattaagcc
    30241 gatcaccttg tccttgtcaa catcataaac tggaatacga gagaagctct gctttaggat
    30301 ttccttgata ttgtctagcg tatcatcgtt aatgtcaatc atgaaggcat ctgtccttgg
    30361 aaccatcacc tcacgcgcca tcatctcatc aagcgagaaa atcccctgca gcatttcaat
    30421 ctcttcggca tcaagcgttg cctcgctgtt agtcagcatg tactcaatct catcacgcgt
    30481 catgcgctca tctgcgtcat caaaggtcat tggggtaatc cggctcagta aatttgtcga
    30541 cgccgataag agccaaacaa agggactaac caatttcccc aagataatga tcactggggc
    30601 agaaatcaca gcaagcttgt cttttagatt catagctatc cgcttggggt ataactctcc
    30661 caaaacaatc gagacatagg tcaagaacac caaagaaata atgctaccag ctgtttgagc
    30721 ggtcgcagaa ccacctaacc agccagaaat aacctgccct aaagaggctg acaggctcgc
    30781 ccctgacaag aggctaataa aggtaatacc aacctgaatg gtcgataaaa agttattggg
    30841 ctgctctaaa acacgcagca agcgatcata cctcttatcc ccatcggcag ccttttgctc
    30901 cacacgagag cgatttaagg ataccagagc catctcactg gctgagaaaa aggcatttaa
    30961 caaggttaga atgactaaca ataaaaactg aatcaataaa ggctgactca cagggtcttc
    31021 cattaatata actcctaaaa cataatatac tacttcatta tatcacaatt gtcgccaaag
    31081 attgctgatt tatttctttt tcctgagaaa tcacagacag tctaagccct gacataaggc
    31141 tggctgaagc ttaatcagta gctgctattt tttccagcat gattaaaaat ggcggctgat
    31201 tcatctgatt gatcggctga tagagcattg ctgttacctg gcgctgattg agctgaccaa
    31261 tatagtccaa aagctcttcc ttctccctac taccgccatc atgaccataa tacaccatga
    31321 tagcaatccg tccacctagc tcaagccgat caagtatttt agctagggct aatatggtcg
    31381 tctcaggcct tgtgatcaac gacttatctg cattgggtag atagcccaga ttaaaaatgg
    31441 ctgcccgaat gggctcctta acatattgat ccacctgctc gtgtccagct aaaataagct
    31501 ctgcattagt caagccttgc tgctccaagc gctcttgtgt cttggtcagt gcctgctgct
    31561 gcacatcaaa agcataaacc ctttgtgaca gacttgctaa aaaggcagtg tcatagccat
    31621 ttcccatagt agcatcaaca gcaatactct gcttatccaa aacttctttt aaaaattcat
    31681 gtgatacatg aataggacgc tttatcatct tatcctccta agcaaatact tcaaatgccg
    31741 cgataccatc tagtatgtct aagtcaatat gccttcggcc gtaacaatct agcacataat
    31801 ctttataccg atctgttttt agattgaatt gaagcgacca gatcagccaa aaaagatcaa
    31861 tatgtcgatc gctttttcct gcctcccccc aatcaatcat ggactgaaat tgccaccgat
    31921 ccaagatcat atttggcaaa caaaaatccc catgaatcag agtttcatgc tgtaacaaga
    31981 gcttaagctc ctgaatccgc ctgtaagcct cctcctggga ctgaaaccgt tgctgaggcg
    32041 gtaaaaagca ctgattgaac cgcccttggt gataaccagc ctcagcagct tcgatatagg
    32101 ctagcgtttt gtcagctaca ggaaaatcag acaaagacag gctatgcagc tttagcatat
    32161 gatcaactaa gatacgacat aagcgcttgg gatcggacaa atattcaata tgactggcgt
    32221 cctctcctgc tacctttgcg gttaaaagcc aatcctgatc accgctgata taatcaagca
    32281 cctctgttgc taagccctta ctatgacaat accgagttag ggcggcctcc ttggcaagcc
    32341 tacctttagc ggctgttttt agaaaatagc cctgcccttt atcaatagca taaacacgtg
    32401 cctctgccga gctactgcta tcataaacca aactgttttg taacagtttt tttaaaacag
    32461 gtggtaggct cagctcctct cctgctatca atctttgttt cattgcttcc cccgattatc
    32521 ccttaagctt acagccctgc cagctatttc ttctttccat ttctaggtca atcgcattca
    32581 aaacctccca tttattcagg ctccacatgg gaccaatcag catgtcccta ggcgcatcac
    32641 ctgtgatgcg atgaataatg atatgctcag gtatgatttc tagctgatca cagataatcg
    32701 atacatagtc cttctgactc aagagctgca agcgtccctc atgatagtct ctttgcatac
    32761 gcgtattggt catcaggtgc agcaaatgca gcttaatgcc ttgaatatca ttgtctgtga
    32821 cacagcgtct aacgttttcg atcatcatct catgggtttc accaggcaag ccattaatca
    32881 agtgagacac aatgttaatg ttagggtact gcctcagacg ctgaaccgtt tccttataca
    32941 agtcataaga atgcgcccga ttaatcagct gggaggtggc ttcataagtt gtttgcagcc
    33001 caagctccac tgtcacatgc atgcgctctg atagctcagc caaataagca atcgtctcat
    33061 ctggcaaaca atcaggcctt gttccgatat tgataccaac aacgccaggc tcattgattg
    33121 cttgctcata gcgctcgcga ataacctcta gcttatcatg cgtattggta aaattttgaa
    33181 aataaaccaa atactgattg acctcaggcc acttgcgatg cataaaatca atttctttgt
    33241 aaaattgttc cctgataggt gcatcaggcg ccacaatcgc atcacctgag ccagaaacgg
    33301 tacaaaaggt gcagccacca tgagcaactg tcccatcacg attaggacag tcaaagccag
    33361 catcaatggg caccttgaaa attttagcac caaataaacg acgataatac tcatttaagg
    33421 tctgatatct ttttgtcatg cctctattgt agcacaaatc ccccgattaa cagcagaaga
    33481 tctcaattgg ctgctacttc tctgattgat gagccaaagc aaggcaacta aaaaggattg
    33541 aagaagacct ctggaagaga cctgccttca atcactagct tttctagaac tgatctgtaa
    33601 cgcgccatac agctgactga tcactggatt tacttttgct ttagctgaaa acgccattca
    33661 aagcgctttt gatcataaaa aggataaagc agctgaagta tgccaaagcc taaggcatag
    33721 ccagccaaca catcgctagg ataatgcact cccagataaa tgcgtgacaa gcctatcagc
    33781 aaaatcaagg ccaaaagggc tatatcaacc agccagcgta aggaggctga ctgcaatctt
    33841 tgatggcaaa taatcagcag acttccaata atcaaaaggc ttcccatcga atggccactc
    33901 ggaaaagaat agccagaagc atgcaccaaa tgctcaatgc tgggtcttgg tctttgatac
    33961 aagagcttta gcacccaaat caaaagggcc gcaaaaacac catttgatag gacaaataag
    34021 gcctcagctc tccagctcaa ggccaataaa gccagcacag caacaacaac aatcactgcc
    34081 tgtgtactaa catttccagc tacagtgatc cctttaaaaa actgggttag cccttcaggc
    34141 agatgacctc ttagggctaa ccgaagctga ctatcaaaag acgttaggtc ttcgggaaaa
    34201 aatttaacaa tatagccaag caccacaaat agtagcatag caaaggaaga caatagcaga
    34261 tgttgttgtt tatgtttcat gatatgaatt cggatatctc tctaaaattg gtttacctgc
    34321 aatatacacg aaataaaaga caattgcaaa tattagcccc tccaaaaggt tgaaaggaat
    34381 gaccattgta aatatgtagc gagcagtacc aataaaagct ttaatatcaa agccagcaaa
    34441 cttggcatat aagggaatag caaagacata gttcatgaca accataccaa gcgttaacag
    34501 ccctgtcccc acaagactag ctagtacata ggtgaccagc cctttctgac gatgccaaat
    34561 caaggcaaag gcagtgataa aaagcgcaac tgctataaca ttcatcggta taccaatcaa
    34621 atcattaacg ccatgattgt ttaaggctag tctaagcaag gtcctcaccg ctaaaatcaa
    34681 gttagcttgc tttagatcca tcaagaccaa gcctaacaaa atcggaatga tactaaaatc
    34741 aatctttaaa aagctggctc ctggaataat ggaaaacccc acaaacatca ggcaaaagga
    34801 tatggctgaa agaatggcaa ccatcaccag ttgatgtgtt tttgacataa aaaattcctc
    34861 caattttgac aaattgaaag aagctccttc gtatgagcag gcaaaaagtc aactcaaaaa
    34921 cccggtcttc tctcttccag actttactgt cggttgtgga atcacaccac atcagcttgc
    34981 gctcgcggac ttctagctgc actagtcacc gccggtcggg aattacaccc tgccctgaag
    35041 acacttatag catagcaaat ttaaacctat agcgcaagac atttttttga agcctagctt
    35101 ttccaacaaa cacaagacat caggcaaaaa agctagatga aagcaacagc aagaaaaatc
    35161 actttgaggc tacaaagctc tctacgaggt aggccaccct gtgacatggc actagcctag
    35221 ctcaaggcaa aaaagagcag actagaagaa acctccaata acctgctctg gtattactac
    35281 cgttgtcccc tttacggtca tagacacacc taaccaatga aaactccaat cagagttttc
    35341 agattgaaga aaaagtccat tttagacggt tttcttcaat ctttttcttt taatcaaaaa
    35401 aacaaaagaa gtctgaaaaa tactgtaata tcagcatttc ccagagtttt catgatatga
    35461 tagtcaattt ctaaatgttc aatttttcta tcgctgatag ggtttgccta cattctgaac
    35521 tccaatcgga gttttttctt tttggcttta gaaaaccttt ggcacagcta atggctccaa
    35581 actggtgatg gtgattcatc agccctctag ggcagcgcct ttgcttctta ctgctgctca
    35641 caccgcaagc tctagcagtg tagtgactgt agctggtagg acagtaagtc cttcttgtct
    35701 cacatcaggc tgctatagcc cctgttctgt gtcttgatcg cctgctctag tgctgtcctg
    35761 ccttgccctc taatgctgct atctagctga ttgacaatgg tctgaatatg atctgcggtg
    35821 tctgtggcaa tccgagatac ctcactgtca tagcgccttt gaagggcatg aaggcgacct
    35881 aaggtcaagg gagcacatat ggactgaact aatctcctat ccagctcttt ctttaaagtc
    35941 ctgatcggct cttgtccggt taagatcatc tctatagcaa tcatctttct tatctccttt
    36001 tccttaacct tcacgccact gacgcctcag cgctgtgatg tccttttcta tcgcctgtcg
    36061 ctggctgcga tagtgatggt caattgcttc ctcctgctgc gacatcttgc gaccttgctc
    36121 atgatagcac tgctctgttc ggtgctggta gtcatcaatc agcctcgtta gaacggtata
    36181 ttggtctgtt atcagactag catcataatg tctgaggtag ctgctaacgg cctgatagct
    36241 agaggcatag agctgctgta gctggttata gttgcctctt aactcgtcat gggctgctgc
    36301 catttggagc cgctcttgat gatagtgctc ctgctgctcc tctagctcct cttccttttg
    36361 acggatagca gttctgatct tttctaatgc tgtcatgaaa agtcgcatcc tagcttttga
    36421 tcaatagcag ctgttctctc aaccccctcc tctagctgct cctttacggt cttgaacttt
    36481 gtggccagtc ctctagcttg agtaaccttg tcatcaaaat gcctcttggt ctgacccaca
    36541 aggctgtcat aggtcac
//
LOCUS       DARYMD010000019        36044 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYMD010000019 DARYMD010000000
VERSION     DARYMD010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36044
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(37..1368)
                     /locus_tag="TU818_000858"
     CDS             complement(37..1368)
                     /locus_tag="TU818_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL0923696.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVVSILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDKKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLSHKNGFKQTFITVFGGTLVAESIIMLTSLFF"
     gene            complement(1459..2238)
                     /locus_tag="TU818_000859"
     CDS             complement(1459..2238)
                     /locus_tag="TU818_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL0923697.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADSVLCDVTNEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAAELGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(2269..2913)
                     /locus_tag="TU818_000860"
     CDS             complement(2269..2913)
                     /locus_tag="TU818_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL0923698.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFTVTPEGIAVEEIHPDYTFEEVQEATEARLIYHN"
     gene            complement(2919..3569)
                     /locus_tag="TU818_000861"
     CDS             complement(2919..3569)
                     /locus_tag="TU818_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL0923699.1"
                     /translation="MNKRISIEEAVNLVKDGDTIMVGGFMTNGSPERLIDALVAKGVT
                     NLTLICNDAGFPDKGVGKMVAQHRFRKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAKVTIVEAREIVSLGDIEPIAVQTPGIFVNYLVEGE"
     gene            complement(3584..4774)
                     /locus_tag="TU818_000862"
     CDS             complement(3584..4774)
                     /locus_tag="TU818_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL0923700.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKSVSAVQLGKVVVEALLEKSG
                     VKPEQIDEVIFGNVLHAGLGQNVARQVGITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSDIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDIFALASQEKAAAAQAAGRFVDEIIPVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALCPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     LGAIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNAAIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
     gene            4966..5868
                     /locus_tag="TU818_000863"
     CDS             4966..5868
                     /locus_tag="TU818_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL0923701.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCAFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
     gene            complement(6765..7907)
                     /locus_tag="TU818_000864"
     CDS             complement(6765..7907)
                     /locus_tag="TU818_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923702.1"
                     /translation="MKALLPFELKKLIRTKSVLGMFIVSLLAIFGLFYINFFNGQISG
                     SSIDKIHGRDAVEINKRFAEEHTGQLSNELLIRTIKDYTLGGSSKNPVFNVYGYYVTS
                     HFDPKFRDYYFNLKKEETIDFSKITPKSQTALGSYLPFKELKLGNFAPWNQLFLVINS
                     AYILLLLLSVYFIAPVFSGDTAKNMNPILLTTRYGRNKLTIAKIISSYLISTSVFVTF
                     YAIILAVFVWYFGLSGWDTSVQLNLYWINSNVNIMAFPEKMTLLGTFINLVTYQFIGL
                     ILITAITILISSKVKSPLTGFALSAASVFVPSFLMDIFQAGIPHKVLSILSVSTASTP
                     NIMLKLAYDGFFGSFWVDGLVIVMIRLAFAFLCLYLAYLSIKRVSQ"
     gene            complement(7904..8767)
                     /locus_tag="TU818_000865"
     CDS             complement(7904..8767)
                     /locus_tag="TU818_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923703.1"
                     /translation="MLLELNQLSKSYGSKNILRRITTQFTPGLYGLLGANGTGKTTLL
                     NLISHFTTPDEGEILLDHKPQSEEFYQHIGFLPQQFSYYGRFSGRDFLLYMAALKGIP
                     KHKAKQETDELLKLVDLYDVRLKRIASYSGGMKQRLGIAQALLNDPKILILDEPTVGL
                     DPKERVKFRNIISELSANKIIILSTHIVSDVEAIAKEIIILKNGQFIHKSSSQELLKT
                     IFGKVWEFSVSDGSPLPRHGQYAVVNEKLVSSSRVFRVVSDEKPNQLAQLVSPTLEDL
                     YIYHFREEQVL"
     gene            complement(8778..9104)
                     /locus_tag="TU818_000866"
     CDS             complement(8778..9104)
                     /locus_tag="TU818_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HEL0923704.1"
                     /translation="MKYVILYKNRSVVKLPISETYDVTTHSSKPHTVVFVTLKGEFGA
                     ATSLRQIEGESAGKLKRCHRQYFINESKISGFDYATRIIKVTDSRISYRRSLLSTELQ
                     VLSRLI"
     gene            complement(9708..9872)
                     /locus_tag="TU818_000867"
     CDS             complement(9708..9872)
                     /locus_tag="TU818_000867"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923705.1"
                     /translation="MDSMTVDAEKASQLDLGIENAGWFHFKLTTAIKLKQVEKVFLFT
                     AIFNRVDEFI"
     gene            complement(10111..11007)
                     /gene="era"
                     /locus_tag="TU818_000868"
     CDS             complement(10111..11007)
                     /gene="era"
                     /locus_tag="TU818_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL0923706.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAVMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGAFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNQKEY"
     gene            complement(11143..11544)
                     /locus_tag="TU818_000869"
     CDS             complement(11143..11544)
                     /locus_tag="TU818_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL0923707.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            complement(11525..12022)
                     /gene="ybeY"
                     /locus_tag="TU818_000870"
     CDS             complement(11525..12022)
                     /gene="ybeY"
                     /locus_tag="TU818_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL0923708.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(12371..12997)
                     /locus_tag="TU818_000871"
     CDS             complement(12371..12997)
                     /locus_tag="TU818_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0923709.1"
                     /translation="MASFFEKLAEHRYLETERLCLRPVTLDDAKAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKETGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKANPALGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDKQKSLASANKPDRYLHNSFESS"
     gene            complement(13052..13627)
                     /locus_tag="TU818_000872"
     CDS             complement(13052..13627)
                     /locus_tag="TU818_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL0923710.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQVPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPQVELVVLVGQYAQQYYLGEGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELVPVLKDKVRQILRG"
     gene            complement(13674..14774)
                     /locus_tag="TU818_000873"
     CDS             complement(13674..14774)
                     /locus_tag="TU818_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL0923711.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDISQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVHFSAKDVVRHPVVAEIIKAYETVGSKAESLKSSPNQLQHQT
                     KAPDRPKTETGQSTSGLTTYEVIGELPKEDKS"
     gene            complement(14877..15092)
                     /locus_tag="TU818_000874"
     CDS             complement(14877..15092)
                     /locus_tag="TU818_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL0923712.1"
                     /translation="MRKAFYTWLMAQRNSTSNKPAALLADLVFEDPTFPKHTDDFETI
                     SRYLEEEASFSFNLGQFDQIWEDYLSH"
     gene            complement(15089..15598)
                     /gene="msrA"
                     /locus_tag="TU818_000875"
     CDS             complement(15089..15598)
                     /gene="msrA"
                     /locus_tag="TU818_000875"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL0923713.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVHNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAERSKQTLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPERYAQSSAIR
                     HQFLEEHWQ"
     gene            complement(15936..16793)
                     /gene="cvfB"
                     /locus_tag="TU818_000876"
     CDS             complement(15936..16793)
                     /gene="cvfB"
                     /locus_tag="TU818_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEL0923714.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHRLGDM
                     VKGFVYTDMKQRLRLTTKPIDARRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLASPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            complement(16927..17484)
                     /gene="frr"
                     /locus_tag="TU818_000877"
     CDS             complement(16927..17484)
                     /gene="frr"
                     /locus_tag="TU818_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL0923715.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            complement(17521..18249)
                     /locus_tag="TU818_000878"
     CDS             complement(17521..18249)
                     /locus_tag="TU818_000878"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL0923716.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGVGIDITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKACD"
     gene            complement(18549..19229)
                     /locus_tag="TU818_000879"
     CDS             complement(18549..19229)
                     /locus_tag="TU818_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923717.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQEYQLTYIFIAHDANICQAICHRVLLLEQGRLVAVRDKEPQTS
                     CGGIGLDN"
     gene            complement(19216..20004)
                     /locus_tag="TU818_000880"
     CDS             complement(19216..20004)
                     /locus_tag="TU818_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923718.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPSNVQMTGRITCQDMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQIIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGQL
                     LVMSKGKIIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            complement(19992..20798)
                     /locus_tag="TU818_000881"
     CDS             complement(19992..20798)
                     /locus_tag="TU818_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923719.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGAKYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            complement(20783..21724)
                     /locus_tag="TU818_000882"
     CDS             complement(20783..21724)
                     /locus_tag="TU818_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923720.1"
                     /translation="MMKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGASSLILPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLIRNAFPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKTKEEACPNT"
     gene            complement(21802..23424)
                     /gene="nikA"
                     /locus_tag="TU818_000883"
     CDS             complement(21802..23424)
                     /gene="nikA"
                     /locus_tag="TU818_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL0923721.1"
                     /translation="MKTKLNVLLLFFFALLLTACQNAKQASYRTDQLRIAWGEDFGDV
                     NPHRYNPDQFVIQDMVYEGLVRYGDKGNIEPALAESWTISPDGKTYTFNLRQAKFSDG
                     SDFNAQNVKRNFDSIFSEQNKGNHNWFHFTNQLDSYKALDDHTFEIKLKEAYSATLYD
                     LSMIRPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHESYWGEK
                     PKLKEVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMS
                     TRLLLLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGL
                     VPYEYNLQKAKDMLTAAGWKENQEGIREKDGQQLRLQVPYISTKATDKDLVEYFQGEW
                     KKLGIDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPEN
                     IALESLPSKAEIDRLIKSVLIEPDGDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYR
                     KGDFKTMRFAPEENALPLRYIEKSAADKAVKN"
     gene            23926..25566
                     /locus_tag="TU818_000884"
     CDS             23926..25566
                     /locus_tag="TU818_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0923722.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWNDVTGSK
                     SPFPLYVTPKNGDKNIKVQQTVVYCFNRDGQWPENWEKRIYESPDKVPHKLPEYNKKS
                     GSDNLFQLLNPKIKIKNPMAALLAVLEDGYPTSSSSGVNQRTTQLAIWHFTDGLSNLA
                     QFHLTPEETSAYNKLIEKGTNASNQSENKLLNKTLDIYSYIDGTGDKKHNYQHLLGST
                     PIPIDNSKENKCQCTKVDLMRTGDGVKIIVYVDNNGNNRYDNGDKMLKEETIKHGQRG
                     PAGESGKPGPKGDRGETGARGPAGPQGKPGKQGPRGDKGETGERGPQGEKGEPGTPGP
                     KGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDGKPGEKGEPGIPGPKGEDGKDGAPGRD
                     GQPGPKGEKGDPGKDGQDGKPGEKGDPGRDGKDGEKGERGEQGPKGERGEQGPQGERG
                     EQGPRGENHTPTPDPMPEPAPKPESKPEPKPTPQPEVKPLPETKPQKPTKPSAMASQP
                     SSKALPKTNDTSGLMTVLGTGLLSLLGLGFLAKRKRKQ"
     gene            complement(25810..26499)
                     /gene="rplA"
                     /locus_tag="TU818_000885"
     CDS             complement(25810..26499)
                     /gene="rplA"
                     /locus_tag="TU818_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL0923723.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(26605..27030)
                     /gene="rplK"
                     /locus_tag="TU818_000886"
     CDS             complement(26605..27030)
                     /gene="rplK"
                     /locus_tag="TU818_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL0923724.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            27266..28063
                     /locus_tag="TU818_000887"
     CDS             27266..28063
                     /locus_tag="TU818_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0923725.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIESVSKGNILVID
                     DTVNHILSKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            28218..28568
                     /locus_tag="TU818_000888"
     CDS             28218..28568
                     /locus_tag="TU818_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL0923726.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(28897..29352)
                     /locus_tag="TU818_000889"
     CDS             complement(28897..29352)
                     /locus_tag="TU818_000889"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923727.1"
                     /translation="MTISDQKVNASQYRWRQYYYRMSPTERELKKEKEVLRNFIATIK
                     LSYSEANEMEAKVYGADSFSKLRAIKEELQSLKSRYFKISNKVEIVSSLIDEHFPEGH
                     SRNIMKKYRLEFLDRLMGIQYDVGLNKDRALDDLSERIIMTRKKLWYIQ"
     gene            complement(29727..32126)
                     /locus_tag="TU818_000890"
     CDS             complement(29727..32126)
                     /locus_tag="TU818_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL0923728.1"
                     /translation="MARRTQRQKNPPKRRLTKAELEKQKAIKRMIASFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLMLAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLAREALEEQEYLANQAINPETGELLAEPEDLLMEMADQKESEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQFKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDYGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
     gene            32246..32419
                     /locus_tag="TU818_000891"
     CDS             32246..32419
                     /locus_tag="TU818_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923729.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAIVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            32506..33312
                     /locus_tag="TU818_000892"
     CDS             32506..33312
                     /locus_tag="TU818_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL0923730.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESET
                     AAKAYEAKIKKALKADADQFPQLNKEVDKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSIDNYSKPIIDSYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(33468..34301)
                     /locus_tag="TU818_000893"
     CDS             complement(33468..34301)
                     /locus_tag="TU818_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL0923731.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGIANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAMTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(34302..35027)
                     /locus_tag="TU818_000894"
     CDS             complement(34302..35027)
                     /locus_tag="TU818_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL0923732.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLEQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKDLKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            complement(35087..36019)
                     /locus_tag="TU818_000895"
     CDS             complement(35087..36019)
                     /locus_tag="TU818_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL0923733.1"
                     /translation="MKKKLSLALSAFLAVFMLVACSNGGNKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKEKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
BASE COUNT        11130 a         8312 c         6478 g        10124 t
ORIGIN      
        1 taatagacca atggttttcc attgatctac tgtgtattaa aaaaacaggc tagttaacat
       61 aataatgctc tcggccacca acgtaccacc aaaaactgta ataaaggttt gtttaaagcc
      121 atttttatgg ctgagaccag taaggctcaa gaaggttaaa aagacgccag actggggtac
      181 aatggtcaaa atattagagg caacagctgc cacacgatga atgatctcag gtgaaacgcc
      241 tgcatctaaa taatattgag caaaatttgg cattacgatc cctaacgctc ctgaagacga
      301 acctgtaata gctgccatag ccgaagtcag gacagtcaag ctgatcacag gtggcccagg
      361 aatattcaaa atgatgtctg agaatacgcc aaaaccagat gctgctgtaa caacagaacc
      421 aaaggctact gcagaggctg tcgcaaagat tggaccaacc gcaccgctag caccaatgct
      481 gagggtcgca attttcttat caatgtactt gttaaataaa acgatagctg aaataattcc
      541 tgtcaagagg gccacataaa tgatattttt cttaacgaat tcgtccccta gcagactacc
      601 tatgatggca ataacaatca agagtatcaa aggcaagatg ctgactacaa atggtggtaa
      661 aaccctttca gttgtatctt catttgtttg actagtatag gtcgcatagt tttcgccaac
      721 ttctaaactc ttagtcaaac aacgcttcat atagaaaaga ccaaaggcga tacagccaac
      781 actccctaaa atacttggca ccaaggctgc ggttagagac gtgttaagat attgtatagg
      841 gataacgttt tgaatcgctg gtgtaccagg taagatcgtc atagtaaagg ttgcaatccc
      901 caaccaaagt ggtacttgaa ttaagttcca tgctaagtcc atctttttaa agagagagcg
      961 tgccaagggt agaacagcaa acatgaccac aaagagacta ataccaccat aagtcaaaat
     1021 agcactgatg ataaaaatag ccaccaagat acggtaaggg ttttgataac ctactttttt
     1081 caagataaat tcagcaatgg aaactgttgc accactgact tccatcaatt tagctaaaat
     1141 agaccccaac aagaagatag caaagtagct catgatatag ccacccagcg cacccatata
     1201 gttatttggt tccttaccca agagtgactc aactagtggc atactattta gaaggacgac
     1261 caaaatcgtt gccataggag ccgcaatggt aatatgaatt tcctttagag aaaaataaac
     1321 gatggcaata atgcccagca agaccccaat tggtcctaaa aattccatag tgtttctcct
     1381 ctcacattca gaaggagcaa gagatagaga aatgtcactc tatctccaat cctcttattt
     1441 acactgaacg gacagctctt actgagcagt gtagccacca tccaagataa ccggttgtcc
     1501 agtaattccc tttgccttat cacttgctag gaaggagaca taatctgcaa tttcttgtac
     1561 gtcaatcaaa cgtttttgcg gtaccaacgg gtacaacact tcttccaata cattttcaag
     1621 cggaatctta cgtgtcttag agaggtcttc aaattggcca cgaacgagtg gtgtgtccac
     1681 atagcctgga cagatagcgt tgactgtgat acctaattct gcggcttcaa gcgctgcaac
     1741 ctttgtcaag ccaatcaaac cgtgttttgc tgaattgtaa gccgcttttc cggcaaaacc
     1801 aatgacacca ttgatagaag ccatattaat gacacgacca aagccttgct ttttcatagt
     1861 tggaaaagcg cgcttaatag cgataaatgg cgctgtcaac atgaccttca acataaattc
     1921 atattttgct gttggaaaat cttcaatcat ggcaacatgc tgcaaacctg cgttgttgac
     1981 caaaatatcc aaacgaccat gcttttcaac tgtataatca atcgctttat tgatcgcttc
     2041 ttcatttgtc acatcacaca aaacagaatc agccgcccag ccttttgtgg tatactcatc
     2101 aacaacagca tctaattttt cttgattgat atctgaaaag acaacgattt tgccctcttt
     2161 taagaatgtt tcaccaattt gtttaccaat accgcttgct gcacctgtta cgaatactac
     2221 ttgtttagac atatttattt cctcactttt tttaaatatt gttttctatc agttatgata
     2281 aattaatctt gcttcggtgg cttcttgaac ttcttcaaag gtataatctg gatgaatttc
     2341 ttctactgcg attccctctg gagtgactgt gaagacaccc atttctgtga caatcttgtc
     2401 aacaactcct gctgctgtca atggcaatga acactccttc aagattttcc atttgccttt
     2461 attggtatgc tccatagcaa caatgacttt tttagcaccg actagtaaat ccatggcacc
     2521 gcccattcct ggaaccattt tccctggaat aagatagttt gcgatgtttc ctttttcatc
     2581 aatttgcaaa gcgccaagaa ctgttgcatc gacgtggcca ccacgaatga tcccaaatga
     2641 agtggtgcta tcaaaaaatg ctccgcctgg tacgatgcca accggctgac cacctgcatt
     2701 aactatagtt ggatcaatgt catcgcctac tttatctaag ccgacaaaac cattctcaga
     2761 ctgcagcatg atagtcacac cttctggtaa aaatctagct accttggttg gcaagccaat
     2821 ccccaaattg accagggaat tatttggaag ctcgagtgcc acacgtttag caattcgttc
     2881 ttgaatttct tctttgctta attctttcac cataacgctc attctccttc cactagataa
     2941 ttgacaaata tgcctggtgt ttgaactgca atgggttcaa tgtctccaag cgagacaatt
     3001 tcacgcgctt caacgatggt cacttttgca tttgctgcca taacctggtt gaaattattt
     3061 tcagagccct tgtagcatag gtttcctaat tcatcagcct tatctgcaaa aattaaagcg
     3121 acgtcagctt tcaatggtaa ttctaacaga taatccttgt cattgacctg taatttttgc
     3181 ttaccttcct ctaccaaggt accgatgcct gtcggagtca agaagccacc cagtccgtaa
     3241 gctcctgctc ggattctttc agccaaggtt ccttgtggca ctaagtcaat cactgtttca
     3301 ccggctgtca tttggcggcc tgcttctttg ttcaagccaa tatgagaagc gataattttc
     3361 cgaaaccgat gttgtgctac cattttaccg acacccttgt ctgggaagcc tgcatcgtta
     3421 caaataagag ttaaatttgt aactcctttt gctaccaaag cgtcaatcag gcgctctgga
     3481 ctcccgttag tcataaaacc accaaccatg atggtgtcgc catcctttac aaggttaaca
     3541 gcttcttcta tgctaattcg tttattcatg aaaccatctc cttttatttt tcaatcaata
     3601 cagacgtccc ttgaccgcca ccgatacaga gtgttgccaa tcctttatgt gcctgacgct
     3661 tttccatctc gtgcaatagt gtgaccaaga tacgcgcacc gctagcaccg atcggatgac
     3721 caagagcaat agcaccacca ttgacattga cgatagccgc attaagacca agctcatcta
     3781 caacactgat agcttgtgag gcaaaggctt cattggcctc caccaaatcc aagtcttcaa
     3841 ttgtccaacc aaccttagca agggccttct gagtggaagg aattggccca gtacccatga
     3901 cctctggtgc tacaccagca cttgcataac ctttaatggc tcccagaatt ggaagaccaa
     3961 gttcttcagc tttgtcacga ctcatgagaa ggacagctgc cgcaccgtca ttaattcctg
     4021 aagcgtttcc tgcagtaaca gttcctgaac catctcggac aaaggccgga caaagggctg
     4081 ttaatttttc aagggttgtt ccagctttaa tgtactcatc ttctgccacc aaaattggat
     4141 cacctttacg ttgcggtact ggcactggaa taatctcatc tacaaagcga ccagcggcct
     4201 gcgcagcagc agctttttcc tgactagcca aagcaaatat atcttgagct ttacggctaa
     4261 tcccatagtt ttttgcgata ttttctgctg taattcccat gtggtaatca tgaaaggcat
     4321 ctgtcaaacc atcattgacc atagtatcaa tgatttttcc atcgcctaag cgaccacccc
     4381 aacggtaatc tttgagcaca tagctggctt ggctcatatt ttctgtccca cctgcaataa
     4441 tgatatctga atcaccacag acgatacttt gtgctgctaa ctcgatggat ttgagaccag
     4501 aaccacagac catatccaca gtgaaggcag gtttgtcgtt tggaatacct gcagttatcc
     4561 ctacctgtct agcaacattt tgaccgagtc ctgcatggag gacatttccg aaaatgacct
     4621 cgtcaatttg ttcaggcttc acacctgatt tctctagtaa tgcttctaca accacttttc
     4681 ctaattgaac agccgagaca gatttaaagg ctccaccaaa tgaaccaatg ggtgtcctaa
     4741 cagctgtagt gataacaact tctttaacca acatgcgatt ctccaatcta tttgttatag
     4801 aaagcgcttt ctgtttttgt gaatttattt tatcactact aaaagcgttt gcaaaattcg
     4861 atttttttat atgactataa aaaattttta ttatttttta ttgacagcta taaaaattat
     4921 tattagtatg aagaaaaaga catctgaaat gaaagaagag gcaatatgga tattaaacat
     4981 ttacgctttt tcattgctat tgtagaaaat aattttaacc tgagccgtac cgctcaacag
     5041 ctttatattt cccagcctac cctcagtatt atgattaatg attttgaaga aaagcagggc
     5101 attaagctct tcaataaaaa atacaataaa atcctcggct taaccatgac aggcaagcaa
     5161 ttttatgagg attctttgga ggttatccgc aaatatgaca agatgcacca aaatctcttt
     5221 tccaccaatc aaaagttgga cggtaatatc actatcggca ttcctccatt aattctgtca
     5281 attgtttttt caaaaatcat gccagaaatt attctagaaa atcccaatat ccactttaat
     5341 attaaggagt atggtgctaa tcggctacgt caggaattga ttttagagaa tgtggatatc
     5401 gccattcttc tgcatcctga acgaattgct gcaaacacca ttgattcttt ccaaatccaa
     5461 gaatctgagc tctgtgcatt tgtctccaag aaccaccatt tggccaataa aaaaatcctg
     5521 acttggatag aactccacaa tgaaaaacta gctatatttg ataaaacctt catgattcac
     5581 catctcatca aggaaaaatg taagtatact gacattaacc cccaaatcat tctggaatca
     5641 gcttcttggg actttctgat caattctact cgtatcaacc ctcaactaat gacgattatt
     5701 ccaaaaccaa cggtagatag ctatggtttt caggatattg tggctattcc tatggagaat
     5761 cctattcctt ggaaagtcat ggttagtcgt ctcaaaaaag atcattattc caccatagaa
     5821 gaatacattt tcaacaaaat gcttgaaaaa tttcatgtaa tcgaatagag actaacaagt
     5881 gatccctttc acatgactgc acgtgccctt cgacatatgg cacctcaact aacccttagc
     5941 gcatatggaa acagctcaat tctttttgaa ggataaaact aaagaggctt gacgatccat
     6001 actaactcag acccaatatt attatcaaga tcctaaatat taacacaact catttataac
     6061 aattaactta caaaaaatgg tctactcctt tgaggcgtga cagcaatact gcaatttata
     6121 aaaaatgact gtcaagacaa tatctctgaa ctcagtcact gtttctcaaa aatcactcac
     6181 atctaatgga gtactatcaa gaaaaagtta tttttaaaat catcaataac ctatctaaat
     6241 tttctaaaca atgccatata aaaagagctg gagtcaccaa gctctaattg atttttacat
     6301 gatgctctat aacaatatcg tttaaagatc attctttttt actagtatgt tgatcacatt
     6361 ttctaaaagc cagaaagaga cttgaatacc gagtcccttt tctttttatc tataaacagc
     6421 cttaaagaag cccagacagg ctgcggtaat tttcttaaca tgagcttcta ctatttctct
     6481 tgttaagccc tgctcacttg atgattcgtt atttttacca cctgaagact ctcctctaca
     6541 taggctactt tgtcatctag ttcctgcttc ttaacgatat atcatcgtct caattgatgc
     6601 cacttccctt atcatcttag aaaaaagcta atttctatac ctttaggtgt tctagatcac
     6661 aaaatagctt tctcaatcct atctaccttg caagaattca ttgaatgccc ttaacttttg
     6721 cagtaacgac aataaaaata gtttagataa cgatgctatt gatgttactg acttaccctc
     6781 tttattgata agtatgctaa atataagcaa agaaatgcaa aagctaatct aatcatgaca
     6841 ataactaatc catcaaccca aaaactgcca aaaaagccgt cataagcaag cttaagcatt
     6901 atgtttggtg tactcgcagt tgatacagat aaaatactca acaccttatg aggtattcct
     6961 gcttggaaaa tatccataag aaaacttggt acaaaaacac tagccgcaga caaggcaaaa
     7021 cctgtcaatg gagacttaac cttacttgaa ataaggatag tgatagccgt aatcaggata
     7081 agcccaataa actgataggt gactagattg ataaatgttc ccaaaagagt cattttttct
     7141 ggaaaagcca ttatattcac attgctgtta atccaataca gattgagttg aacactcgtg
     7201 tcccaaccac ttaatccaaa ataccaaaca aagaccgcta atattatggc gtaaaaagta
     7261 acaaacactg aggtgcttat caagtaacta cttattatct tggctatcgt aagtttatta
     7321 cgaccatacc tagttgtcaa taaaatagga ttcatatttt tagcagtatc accggaaaaa
     7381 acaggagcga tgaagtaaac agacaaaaga agaagaagga tataagcact atttatgacc
     7441 agaaaaagct gattccaggg tgcaaaatta cccaacttca gctctttaaa gggaagataa
     7501 gagccaagag ccgtttgaga ttttggggtg atcttactga aatcaatagt ctcttctttt
     7561 ttcaaattaa aataataatc tctaaatttt ggatcaaaat ggctagttac atagtagcca
     7621 tacacattga agacaggatt ttttgagctg ccacctagag tataatcttt gattgttcta
     7681 attaataact cattggacaa ttgaccggta tgttcttccg caaatcgctt gtttatctca
     7741 acagcatctc ttccatgaat tttatctatc gaagaaccac tgatttgtcc attaaaaaag
     7801 ttgatataaa ataacccaaa gattgctaat aagctaacaa taaacattcc caaaactgat
     7861 ttggttcgga tcagtttttt taattcaaat ggtaagagag ctttcataac acctgttcct
     7921 ctctaaagtg ataaatgtat aagtcttcta aggttggtga cactagttga gccaactgat
     7981 ttggtttctc atcactaacc acacgaaaaa cacgactaga tgaaactagt ttctcattga
     8041 ctacagcata ctgaccatgc cttggtaacg gcgaaccatc agagacagaa aactcccaga
     8101 ccttgccaaa gatggttttc aacaattctt gactactact cttatggata aattgaccat
     8161 tttttaaaat gataatctcc ttagcaatag cctcaacatc agagacaata tgagttgata
     8221 agataataat tttgttggcc gacaattcgc taataatatt gcgaaacttc accctttctt
     8281 ttgggtctaa tccaactgtc ggctcatcta aaatcaagat tttagggtca ttgagtaagg
     8341 cctgggcaat accgagacgt tgcttcatac caccagaata agaggcaatc cgcttcagac
     8401 ggacatcata tagatccaca agttttaaca attcatccgt ttcttgcttg gctttatgtt
     8461 taggtattcc ttttaaggct gccatataaa gaagaaagtc tcgaccagaa aaacgaccat
     8521 aataactaaa ctgttgaggc aaaaaaccaa tatgctgata aaattcctct gattgaggtt
     8581 tgtgatccag taaaatctct ccttcatcag gagtcgtaaa atgactaatg agattgagca
     8641 aggtcgtttt ccccgtccca ttagccccta aaagtccgta aaggcctggg gtgaattgag
     8701 tagtaatcct tcgcaaaata tttttcgatc cgtagctctt actcaattga tttaattcta
     8761 ataacataga accctcctta aatgagtcta ctgagcacct gtaactcagt actcagtaga
     8821 cttctcctgt acgaaatcct gctgtctgta acctttatta ttctcgtagc ataatcaaat
     8881 ccagagattt tcgattcatt aatgaaatat tgacgatgac acctttttaa tttcccagca
     8941 ctttctccct caatctgtct cagtgacgta gctgccccaa attccccttt tagggtaaca
     9001 aatactactg tgtgaggctt agatgaatgt gttgtcacat cataggtttc agagattggt
     9061 aatttaacaa ctgacctatt cttatataaa ataacatatt tcattgacgt cctccttctc
     9121 tatttatatc ttaatacaag tacaagcatt gagacggtaa agtctcaaat ggtatctatc
     9181 atatcctgaa tggtatcaca gtagctgttt aagatgtcat agaggcattt gagaaatgta
     9241 acctgttttc ctttcgtttt ttgatcatat gatattgtat tagttcggag aaccatggta
     9301 atcattcaaa tcttacataa acctctcttg ggatatggta ttagcgtcta tattaattac
     9361 tacttcaaca gacacctttt taaagctgct aaaattgtca gtggcaaaca aataggctat
     9421 aggtataaat ctcacactta ttttatcata aaatcattct ttttatcatc taatcaaatg
     9481 tacaagcact ttaaagttat tctcatgact ctattattct tattggaagc catattaatt
     9541 acgacgacat tttcagaaat cattatcgtg tgtttggtat catcgacaca accgctaata
     9601 aatcgtttaa atgtatccaa aaccaaattc atgattacct gttcaaagaa taaccagagg
     9661 gcttactgat tgctttaaca aatatttcta gtcttctcat tttgtactca tataaactca
     9721 tctactctat taaaaattgc tgtgaacaga aaaaccttct caacctgttt cagttttata
     9781 gccgtagtta gtttaaagtg aaaccaccct gcattttcta tacctaaatc caattgactt
     9841 gctttttcag catcaacagt catgctatcc ataagataac acaccacgat gtgttgtgat
     9901 tattgttctt ctatatttag ccttacctcc tgaaaacaaa aaaagagaac accttttaaa
     9961 tgttctcata taagcaatct tatatattaa atgaggattc gatctaatga caagacagcc
    10021 ttattgctac caataatgca gcttaccaaa caagggcaat cagtataagg gttgctaacc
    10081 agctctgctg acatagcctg ctttgagcga tcaatactcc ttctgattat agccaaagtc
    10141 agctaaatca agctttttgt cacgccagtt tttcttaacc ttgacccagg tctccagata
    10201 gaccttatcg cctagcatta gctcaatatc acgccttgcc agcttaccga tttttttgag
    10261 catggcgcct tgttttccaa taataatgcc tttttggctg tcacgctcta ccatgatggt
    10321 aactcggata tgcaccttgt cagtcacctc atcacgcttc atcgaatcga ccacaacagc
    10381 aactgaatga ggcacctcct gctgtgtcaa gtgaagcacc ttttcacgaa ccatctcaga
    10441 aacaagaaag cgctctgggt gatcagtgat ttgatcctct gggaaatact ggaagccctc
    10501 ttcaaggtta tcctttaaga gctgaacgag cgtttcgacg ttgtttcctt gaagtgctga
    10561 aataggaaca atttccttaa agtccatctg actacggaaa tcatcaatct gctccaataa
    10621 ttggtctggg tgaaccttgt caattttgtt gatcaccaaa ataaccggaa tacgagcagc
    10681 cttgaggcgt tcgataatca tatcatcacc cttaccacgc ttttcatcag caggcaccat
    10741 aaaaagaacc gtctcaacct cacgcagggt actataggct gattccacca taaaagcacc
    10801 taaggctgtc ttaggcttat gaatgcctgg cgtgtcaata aaaacaattt gctctgtctc
    10861 tgtggtatag attcccataa ttttattacg ggttgtctgc gccttatcgc tcataacggc
    10921 gattttttgt cccatgacat gattcaaaaa cgttgatttg ccgacatttg gtcggccaag
    10981 aatggcaaca aagcctgatt taaacataag ctactaaggg cctaaaggat cagtcaaggt
    11041 aagaatcaag cagcaggcta ttcacctgat tgctttccta aagcttatac tcctttcctg
    11101 cgctgcacta tcgcacagga tagcccattt cctttcattt ttttaatggc ataacattcg
    11161 ccaaattttg ggaacaaaga taatcagccc cgtcaaaaca gcatagcctg aaatgaccag
    11221 gacagcacct gcagccatat ccttggcatg cttagccagc atggagaaat ggtaatcact
    11281 tgccaagtca accacatttt caatagctga attgacaatc tctaaggtaa tcaccaaaaa
    11341 aatagccagc aataaaaaca gccattctat agcagaaata ccaaaaacaa tcccagccaa
    11401 agaggctaac agggctgaca aaagatgact tcttaggtta cgctcctcct taaaggctgt
    11461 cagaacccct gtcaaagcaa attctaagct ggcaattact gttctgtttt tccatttgcg
    11521 tttattattg tcttgtgagg ccataagcag tcaaaatctc ttcctgtaac gtaaacatct
    11581 ctttttcttc ctcaggagtg taatgatcat aaccattaat atgcaaaaaa ccatgaacag
    11641 ccaagaagcc catctcacgc tcaaaggaat gcccataggc ttctgcctgc tcatgggctt
    11701 tgtcaacaga aataaacagc tccccaatat aagcatcaaa ctcctgtatc atacctgcca
    11761 agtcaggatc aagctccaaa tcctcttggc taaaggcgat cggaagctct ggcttgtact
    11821 ccagagaaat cacatcagtc ggacgatcag tatcacgata ttcaagattc aaggcgtggc
    11881 ttctatcatt ggtcacaaag gtaaccgcca tttccttgtc ctctttacca attgttttgg
    11941 cagcaaaatt gagcaaatca atggtttgct ccatcatctc ttgagaaacc tgcttagttt
    12001 catcaatcat ctctatatac atcattatat gaagaggtcc tagcaagaca ggtccaaaca
    12061 aacaccacac tgctaggtca aaaagcttga tacctcttat cctttcaaca tcatttcagt
    12121 actttctttc cattatacca caagaaaaaa gaaaaagcag gcattagtct agcctgctcc
    12181 aaaagaagcc ggaataatga caagatcgtt gataccccag cagctgctgt ttctggaata
    12241 cccagagcct gctgcgcaga atacagtcct cttagatagc tgggactcct aggattacaa
    12301 tagtagataa gcctttagac cacttccatc gcctaaaaac taatcctaaa cggctttccc
    12361 ttagatacca ctagctgctc tcaaagctat tgtggaggta acgatctggc ttattggctg
    12421 acgccagtga tttctgcttg tcataatctt ctttggttaa ataatagtgc agcactgtca
    12481 caaaacggtt ggaatcaagg tgatcacgct tagcatatgg ctcttcatgt gaaaagcaca
    12541 tgccgctttt agccataaca cgtcccaaag ccggattggc tttatcatgc ttagcaatca
    12601 cacaattcat gcctaaagct tcaaaacaca agaccagtac agccttgaca gcctctgtcg
    12661 catagcctct tccccagtga tgcttatgaa gacaatagcc aatctcagct ctacctaaat
    12721 ccagctgtat atgatgaaga tcaagcgtcc caataaagtc tcctgtttcc tttaacacaa
    12781 tcccccaccg tccaagtgga ctagccagat agacagaagc aatgacttga cgggtctcct
    12841 caattgtctg attggctgga aagctatacc tgacagtctc ttcatcagaa gcataatcaa
    12901 acatggcttt ggcatcatcc aaggtcactg gacgcaggca tagacgctct gtctcaagat
    12961 acctatgctc tgctagtttt tcaaaaaagc ttgccactac tactctccct ttcctaaaaa
    13021 tctaactcac ctaacagcat gactgcctgc cctagccgcg taaaatctgc ctcaccttat
    13081 cctttaaaac aggaaccagc tcctcttcaa accaagcatt tttagccaac caaagctgat
    13141 ttctaggaga tgggtgaaca aggggaaaat aatccggaag atagtcctca aaatgctgca
    13201 ccgtttcggt aagattgcgt ctacaacctt caccaaggta atattgctgg gcatactgtc
    13261 cgaccagcac caccaattca acctgaggca tcaaggccat taacggacca tgccacttgg
    13321 cagcaaagcc ctttcgcggt ggtaaatcac ctgattttcc cttaccggga taataaaaat
    13381 ccataggaag aacgccaaac aagcccgact gataaaaggt cctgtcatca acacccagcc
    13441 aagctctcaa gcgaactccg ctacgatcat tccagtacag acgcgtctcc tgagctacaa
    13501 taccaggcac ctgaccaaca atgactatcc gagcggtctg aggagctgca taaagtggtt
    13561 cgataccttt tttggtatag tcacgattgg caggatcagc cataatcgct tgcaatagct
    13621 ctgtcatgat accctcactt tcataaaagg ctcttcaggt gaagagctct tttttacgat
    13681 ttgtcttctt taggcagctc tccaatgacc tcataggttg ttaagcctga cgtagactga
    13741 cccgtctctg ttttaggccg atctggagcc ttagtctgat gttgcagctg attagggctg
    13801 ctttttaatg actctgcttt tgaacctaca gtttcatagg ccttaataat ctcagcaaca
    13861 acagggtgac gcaccacgtc cttggctgaa aaatgcacaa aatcaatctg cttgatggcc
    13921 tgcaattttt gagctgcatc aatcaagcct gatgtgatat gacgcggcaa atcaatctga
    13981 ctaatgtccc cattaacaat cattttagac tgaaaaccaa gtctggttaa aaacatcttc
    14041 atctgcatga tggtcgtgtt ttgcgcctca tctaaaatca caaaggcatc atctaaggtc
    14101 cgaccacgca tataagccaa gggagcaatc tcaataatat cacgctccat taaccgagta
    14161 gtctgctctt taccaagaat ctgataaagg gcatcgtaga ctggtctaag gtaaggatca
    14221 accttttcct tcaaatcccc tggtaaaaag cctaagcttt ctcctgcttc aacagctggg
    14281 cgtgtgagaa tgatccgctt aacctgacca cgctttaaag cagtaactgc tagcgtaact
    14341 gctaaaaagg tctttcctgt tccagccgga ccaataccaa ataccacatc atgatgcttg
    14401 atactatcaa cataggcctt ttgccctagc gtcttaacac gaattggctt gctataaaag
    14461 tccttgataa tctcttcctc ataaagagca acaaattgat caagcctatc tgaatccgcc
    14521 atagacagcg cagtcaccac atcagaggta ttgataacca tgccacgccc caccaaaact
    14581 aaaagggctt gtatcgtcaa acgcgctagc tcaacagccc gctcatcatc accaataatc
    14641 tgaactcgct cagttctagc atgaatcaca acattgaggt gagattctat catcttcaaa
    14701 tggcgctcat tgctaccaaa aagagctaac agatcatctg ggtgattcaa gctaatgtca
    14761 gtcgaataat gcaaatttgt cttccttttc catctataag taactctatt ataacaaatt
    14821 ttgctataaa tcgggaataa gacccagctt taaagcctaa aagagctagc ctatggctag
    14881 tggctaaggt aatcctccca aatctggtca aactgcccca gattgaatga aaagctcgct
    14941 tcctcttcaa ggtaacgact gatggtctca aaatcatctg tatgctttgg aaaggtcggg
    15001 tcctcaaaaa ccaaatcagc taataaagca gcaggcttat tagatgtcga gttgcgctga
    15061 gccatcagcc aagtgtaaaa cgcctttctc attgccaatg ctcctccaaa aattgatgac
    15121 gaatagcact actttgtgca taacgctctg gattcttttg ataaaagccc tgatgatagt
    15181 cctctgctag ataaaaaggc tctgccggtt caatgcttgt cacaatgggc tggtcaaagc
    15241 gccctgaggc ctgcagggtc tgcttggacc gctctgcaat ttcccgctgc cgctcatcag
    15301 tatagtaaat caccggccga tagttgtctc ctctatcctc aaattgccca aaggcatcgg
    15361 tcgggtctgt ctgagcccag taaagctcta ccaaatctga atagctgatc agactcggat
    15421 caaagataat ctcaacagct tcagtatggc ctgtcgtctt tgagcaaacc tgctcatagc
    15481 ttggattgtg aacatgccct cctgtgtagc cacttctcac tgataaaata cctgcctgct
    15541 cctcaaaagg ctgcaccata caccaaaaac agcctcctgc aaaaattgct ctttccatac
    15601 ctaatctcca ctttctttgt ccttacatta gtgattttca ttgtaacaaa aaaccttgcc
    15661 agaggcaaag cttaatataa aacaagtcac agactcaaag taacaagact cctcagccca
    15721 actagtgcct agcactaagc agtactgtca agcagccact actagatcaa gagggccaca
    15781 cagagctttt tcgacaacaa aaatgattgg cgctttaaaa caggctatca gctaagctcc
    15841 acactcaaaa taaggaagct agctatactg ataaaggata agtcttagca acaccgatcc
    15901 agcttatgat tataggctaa gagacagaca gctccctatg atatcagctc agttcctgtc
    15961 acgtcctgct tgatcttgtt agccttcatc aaaccaccta aggccttttt aaattgaccc
    16021 ttggaaatcc caaaggttgc cttgatatcc tctgggcttg acttatcatt aagagtcatg
    16081 tagccaccat tagacttgag ataggtcaga atcatctggg catcgttttc cagcatttca
    16141 aaggaacgcg gctttagcga aaggttgagg gtacggtcac gttctctaaa gccaatcacc
    16201 cgagcggtca aaacctgccc caaacgaggc tccgtataac gctcgctagg gtggataaag
    16261 cccagcatat tattttctgg caggtaaaca aaggtccctg atagcttcaa gcgatagaca
    16321 atagcaggca ggctttgatt ttgcatgtta tcataggctg gactagcaag cctttgaaat
    16381 atctctggct cagctggcaa accccagata cgatcttttt tgtcaaccac aagcttaaga
    16441 taaagcctgt ctcctttttt aggccaaaga tcctttagct ccggcaaaac atctaaggaa
    16501 accacaatct ccttatctgg aataccagta tcaacaaaca ccccaagatc acgacggaca
    16561 gtggtcacct cgccccagcc ataatgatca cgccttgcgt caataggctt cgtggtcaag
    16621 cgtagtcttt gcttcatatc tgtatagaca aagcccttaa ccatatctcc taatctatga
    16681 ctgccttcct ccttagctag agcaaagctc agcccctcct tttggacaag ataaaactga
    16741 ctattttctt cttttactaa gccagtgata actgttgcta ataaatgatt catatctttt
    16801 tgttctttct tttaaaaaat agggacaagt ccaaagcagc tgctttttag ccttgtcacc
    16861 tatcctgtta tgcctgatgt gtattaggtt acgcagctga tctagcttaa tgatcagata
    16921 agccgcttaa actgaaagta attccttttc tttgtcagca gtcattcggt caatctcttt
    16981 gacagcctca tctgttgctt tttgaatatc cttttccaag gcttttaact catcttcagt
    17041 gatttcctta gccttctcct gctttttagc ctcgtccata gcatcacgac gaatattgcg
    17101 aatcgaaacc ttcgcagtct caccaacctt tttcacttcc ttggctaatt ccttacgtgt
    17161 ttcttctgta agcgctggaa taaccaagcg gatgacagag ccatcgttag ctggtgtaat
    17221 gcccaaatca gaagcattca aggcacgctc aatatccttg attgatgatt tgtcaaatgg
    17281 tgaaatcaaa agcacacgcg cctctggtac tgtaatagaa gccaattggt tcaacggcgt
    17341 tggtgcacca taataatcca cctgaatacg atccaaaagg ctagcattag cacgacctgc
    17401 acgaatgctt gcatactcgc gtgctagtga gtgatgtgac tgtgtaaaac gttctttcgc
    17461 agtttcaata attgcatttg ccatgattgt ttttctcctt aatcctttag ctctaaaatc
    17521 ctaatcgcag gccttatttg ataccgttgt gccaatatgc tctccaaaga ccacacgctt
    17581 gatatttcct gcttcattca tattaaagac aaccaaatca atatcattat ccattgacaa
    17641 ggttgaagct gtcgcgtcca taatcttgag accgcgcttg ataacctccc catgagtcaa
    17701 ttcatcaaac ttaacagcgt ttgcgtcctt tcttgggtca gcattgtaga caccatcaac
    17761 accattttta gccatcaaga tagcatctgc ctcaatctca gcagcacgta aggccgctgt
    17821 cgtatctgtt gaaaaataag gtgacccaat accagcaccg aaaacaacaa tgcgcccctt
    17881 ttccagatga cgaagcgcac gacctcgaat ataaggctct gcaacgtttt gcatgggaat
    17941 agctgtctgc acacgagtat caacgccata atgctgaagg ctatcagcca ttactagagc
    18001 attcataacg gttccaagca tgcctgtgta atcagcctgc acacgatcca taccagcctc
    18061 tgcagcaggc tcaccgcgcc agagattacc accaccaata acaagagcaa tttcaacacc
    18121 tgaattgtga acttctgcga tctctttagc aatcgactga accgttgtta tgtcaatgcc
    18181 aacaccctta tcaccagcca aggcctcgcc agacaatttg attaaaatac gttgatattt
    18241 aggtttcact atttatgatc tccttatttt gtccctacca ttctaccaca aaacaaaaaa
    18301 atttaataga ccaatgcaag agaggaaagc gaaatttttg acgatccttt tatcaagatc
    18361 cctttgagca gcaaaaaaga tgagtcatta taaaaagagc attatcgtat ccgaatagca
    18421 cagttataac ctattaatac gacaaaaacc agaacaacta tgacaaaaaa acgccgtaaa
    18481 aaagacttaa aatcaagcct caagccagac tagattctaa gtcgtgctat attgagagat
    18541 gatttgtttt agttatctag cccaatgccg ccacaagaag tctgaggctc cttatctctg
    18601 acagcaacta gcctcccctg ctccagcagc agaacacgat gacaaatggc ctgacagata
    18661 ttagcatcat gcgcaataaa aatataagtc agttgatact cctgctttaa ctcatagagc
    18721 aagtccaata gctgcccttg ggtaataggg tccaagccac tcaaagcctc atcaaaaatg
    18781 atcacctccg gccttaacaa aagagctctc gctatacaaa cacgctgtag ctgaccacca
    18841 ctcagctctc tggccttttt acccagatga gtggcgtcaa gaccgaccgc agctagtatt
    18901 tgaacaacct cctctaaggc aaagtcctta gaaagggcct ctgtcaatat ctcttgaata
    18961 gtaaagaggg gattgactga tcttagcgca tcctgaaaga caagtaaaat ccgaggtcca
    19021 catactttta cagaataggg ctgaccatga aagagcacct gaccagctgt cggctgctct
    19081 agcccaatga ttaacctagc aagcgttgtc ttgccactac cactttctcc cataatccca
    19141 aggctctcac ccttttccat ttgaaaatga caatctgtta gcactggctt ttgatgaaag
    19201 ctcttataaa catgtctaaa ctctatcata gcgtatcagc cgatcataat gattttgcaa
    19261 aagcaactcc ttggtggcag cctgacttgg ccgatgaaaa atcgactcaa cacttccctg
    19321 ttcgatgatt tttcccttac tcatcaccag tagttgccct cccaaagtct gtgccaattg
    19381 gtaatcatgc gtcactgtaa taatggtttt tcccttgtcc tgcaataact tcagcatccg
    19441 tatgatatta gaacgattgg catcatctaa agcagaggta ggctcatcta aaatgataat
    19501 ctgtgggtct aagcacaaca aaatagctag cattacccgc tgtagcatac caccacttag
    19561 ctcaaagggg tacttcctca gcagctcctc tggctgctct agatagagct ctcgcatgaa
    19621 aggcagagcc ctttttagac aggccctttt tgaaagtctc tcatggcttc ggatggtttc
    19681 aaggagatga gcctcaatgg tctgaaaggg attgaacatc gccataggat tttggaccat
    19741 ataggccatg tggcgccctc taatgctctg ccattgctta gcatctaatt gatctagtct
    19801 catatcttga caggtaatcc tccctgtcat ctgtacattc gacgggcatt gaccaattaa
    19861 tagcttagtc aagagggtct tgcccgaacc actcctgcca acaatcacca aggagctccc
    19921 caagggcaac tcaagattga gcttacttaa tagcacatca gagccattat aagccgataa
    19981 atcattaaca attaaccgtt ccatgttttc ctccacccct tagcatcagc gtaatcacct
    20041 aggctgttaa aagctagcac agtcactaaa atggcaagcc ctggtgacat catgagccac
    20101 agagctgtcc taaaatagct ccttgcatca tgcagcatca ttccccattc tgtcacattg
    20161 ggctgaacac cgatacccaa aaaagaaaag cttgagatca tgagaataat attgccaata
    20221 ttcatcaaag ccaacactac aatcggccga taaacaaatg gcaggatatg cttttttaag
    20281 atatgccgca cagataagcc cattgtctgc gcactaatga catatggctc tgccttagcg
    20341 cttttgacca tcgtgaccat cagcctagca taatacagcc actctaccag aacaatagct
    20401 aggatcatgt tgcctatgcc ctgcccaagt atccccattg tagctagcga tagtaaaaag
    20461 ctaggaaagg cagaaacaac atcagctagc cacagaaaag ctgcctcgag ccttccttga
    20521 taccagccta caaccaaacc aaccacagca ccaatagata gctctaacaa actaatagta
    20581 accgccaaaa gcaaggaata cttagcccca tataacaagc gcgacagcac atctcttccc
    20641 aattggtcag ttcctaataa gtgctgctga ctaggtggca tgagcttact agcaacatca
    20701 acagcatgag gatcaaaggg agcaagataa ggagcaaaca agacacagat aaacaacagc
    20761 aatagcataa cagctgaacc aattacgtat ttgggcatgc ttcctccttt gtcttgcgca
    20821 gacgagggtc aataaaagac actagctctt gagttatcac atggtgtagt aaaaacaaag
    20881 caccaaataa gagcatacag gcctgaataa ccggaatatc tgctgctttc agactcataa
    20941 caaatagact gccaatacca ttccatgaga aaatatcctc aacaataata gagcccgtca
    21001 tcaaataaac aaaggtcaag ctcaagcctg ttgcaatagc aggaaaggca tttctaatca
    21061 ggtgatgctt aacaatataa taggtcttaa cccctcttag cctggcattt tcaacatgca
    21121 gactcgttag ctgctcactg attgcctttc gtatcaaggc agtatattgc ccaatcaagg
    21181 aaaagctaag cgtaatactc ggcaaaatga ggctgctggc acccgccttg cctgacacag
    21241 gcaggagatt tagcttaaca gaaaaggcta taatcaagag atagcccaac caaaagctag
    21301 gcattgacac agcgacaaag ctgaataaac gcaccagccg atcaaacaag gaatgctcaa
    21361 acaaaccact gcctaccccc aaaggaaagg caatcacaag taccagtaaa aaagaggtca
    21421 agcttagcat tagcgttgct aaaaagcgct ccaccaccaa aggcaggaca gggaccttta
    21481 acacgtaaga ggtcccaaaa tttcctacaa gaatgtcaga taaccaggtc acatactgct
    21541 cccataaagg cttgtctaag cccaaataga gcctagcatt gtgaagagct tctggtgtaa
    21601 tactgatctt agataggcgc aaatactgct ctgccgggtt agcggaggat agcttaacca
    21661 gaacaaaggt cactatcgaa atcattagca aggcgccaaa ggtagaaata agcttcttca
    21721 tcatattttc tctcaaccct tcactaagac atcagacaag aattgtcagg atagtcactc
    21781 acaaccagtt cctctgctct atcaattctt gactgcctta tcagcagcac ttttttcaat
    21841 gtaacgcaat ggaagggcat tttcctctgg tgcaaagcgc attgtcttaa aatctccctt
    21901 gcgatatact gaaacaactg actgataggt gagtggaata taaacagcct catcatgcaa
    21961 caatgacaat acctgcttat agcccttgtc taccttatcc ccatctggct caatcaaaac
    22021 agatttaatc aggcgatcaa tctcagcctt tgatggcaaa ctctccaagg caatattttc
    22081 tgggtgacca tgatccgctt ttgccgttaa ggctgtcatc caagcatgag gatcccaagg
    22141 agctccccat gaataggtca gcatcatatc aaactgccct gtcttggcat tagcccagta
    22201 gtcatcctcc tccatagctg tcaagaccac atcaatccca agctttttcc actcgccttg
    22261 gaaatattca accaaatcct tgtctgtcgc tttagttgaa atataaggca cctgtaaacg
    22321 caactgctga ccatcttttt ccctaatccc ttcttggttt tccttccagc cagcggctgt
    22381 cagcatgtcc ttagcctttt ggagattgta ttcataagga actaagcccg catcagcatg
    22441 cggtgttgtt tttgaaaaaa tggtatctgc tgctgtctct gttcctctaa aggtgtgctt
    22501 agcaatagcc tttttgtcaa ccgcatggtt cattgcctga cgaacccgct tgtcctgaaa
    22561 cactgactgc ttagcattta acagcaataa acgagtcgac atgggctgag aaacatcagt
    22621 aacatacttc ttgtccttag catactgcac aaaggtatca agactaatca gaccatttcc
    22681 atagatcaaa tcaatatccc cagcctcaaa tgctaaggct cttgtctcag catcaggcat
    22741 aatcttgatg gttacttcct ttagctttgg tttttctccc caatagctct catgacgtgt
    22801 aaaggtaatg tactcatttg cctttttctc tttaacaacc cattgacctg taccaatcgg
    22861 ctttttaaca ttgtgcttat tggtgtcatc gccatcagga aaaccagcat cagccaaaaa
    22921 cctaatcggt ctgatcattg acaaatcata caaggtagcg ctataagcct cctttagctt
    22981 aatctcaaag gtatgatcat ctaaagcctt gtagctatcc aattgattgg taaagtgaaa
    23041 ccaattatga ttgcccttat tctgctcaga gaaaatcgaa tcaaaattcc gtttaacatt
    23101 ttgagcatta aaatcagaac catctgaaaa tttagcctgt ctcaggttaa aggtataggt
    23161 tttgccatct gggctaatcg tccagctctc tgctaacgcc ggctcaatat tacccttgtc
    23221 accatatcga accaagccct cataaaccat gtcttgaata acaaactgat caggattgta
    23281 gcgatgagga ttgacatcac caaaatcctc accccaagca atcctcaact gatccgtacg
    23341 gtaagaggcc tgcttagcat tttgacaggc cgtcagcagc aaagcaaaaa agaataacaa
    23401 tagcacattc aatttagttt tcattatgtc attaactttc taaagatatt aatctatcta
    23461 attttagatg tggtttatca caaaattaag tatggttaat ttaatcattt tatagccctc
    23521 ttgtcaagaa aaaatgagac aaaatcagcc tagaaaaagc cagaaggcta caaataagca
    23581 aatcgtcaaa atcatgaaca cttcaggctt gctgaggaat attttctaat ggttattaga
    23641 aataatgaac aattacctaa caaaagactc caaaataaag gtaaaagacg aacattcacc
    23701 ttgctgctca gctaccaaga caaacaatcc tgatagcatc aattttcttt aggctcttag
    23761 caattagttg caatatcaga taattttgaa tttaattaaa aaaaacgaaa ctacggagac
    23821 caattatcag aaagctattc acagccagca aagggcatgc taaagtatta tctggaaaaa
    23881 gaaaggctta ggaatgatta tttctaaact aaaaggagag agacaatgaa aaaaacaatg
    23941 aagaagatgc tagcagcctc gacgctctgt atcatcatgt caggcagctt catcagcggc
    24001 tcagctagag tgttagcgga ggaatattat gggtggaatg atgtcactgg gtctaagtca
    24061 ccatttcctc tatacgtgac accaaaaaat ggagataaaa atataaaagt tcaacaaacg
    24121 gttgtttact gttttaacag ggatgggcaa tggccagaaa attgggaaaa acggatatat
    24181 gaatctcctg ataaagttcc acataaatta cccgaatata ataaaaagtc aggaagcgat
    24241 aatctgtttc aattacttaa tcccaaaatt aagataaaaa atccaatggc agctttatta
    24301 gcggttttgg aagatggata tcctacgtca tcttcttcag gagtaaatca aagaacaact
    24361 cagctagcta tttggcattt tacagatgga ttaagcaatc ttgcccaatt tcatcttact
    24421 ccggaagaaa cttcagctta taacaagttg atagaaaaag ggacaaatgc ttctaatcaa
    24481 agtgaaaata aactattaaa taaaacttta gatatttatt cctatataga tgggactggt
    24541 gataagaaac acaattatca acaccttctt ggctccactc caattcctat tgataattct
    24601 aaagaaaata aatgtcaatg tacaaaagtt gacttaatgc gaactggaga tggggttaaa
    24661 atcattgttt atgttgataa caacggaaat aatagatatg acaacggcga caaaatgcta
    24721 aaagaagaaa ctatcaaaca tggtcaacgc ggacctgctg gtgaatctgg gaaaccaggg
    24781 cctaaagggg atcgaggaga aactggagca cgcgggccag ctgggcctca gggcaaacct
    24841 gggaaacaag gacctagagg tgataaagga gaaaccggag aacggggacc tcaaggggaa
    24901 aaaggtgaac ctggaactcc tggtcctaaa ggagaagacg gtaaagacgg ggctcctggg
    24961 cgtgacggac aaccggggcc taagggtgaa aaaggtgacc ctggaaaaga cggacaagat
    25021 ggaaaaccag gggaaaaagg agaacctgga attcctggtc ctaaaggaga agacggtaaa
    25081 gatggggctc ctgggcgtga cggacaaccg gggcctaagg gtgaaaaagg tgaccctgga
    25141 aaagacggac aagatggaaa accaggggaa aaaggtgacc ctggacgcga tggtaaagat
    25201 ggagaaaaag gcgaacgcgg tgaacaaggg cctaaaggag aacgcggtga gcagggacct
    25261 caaggagagc gtggggagca aggacctcgt ggggaaaatc atactcctac cccagaccca
    25321 atgcctgagc cggcacctaa accagaatcc aaacctgaac ctaagccgac acctcaacca
    25381 gaggttaagc ctctgccaga gactaaacct caaaaaccaa ccaagccgtc agcaatggct
    25441 agccaaccaa gtagcaaagc actaccaaaa acaaatgaca ctagcggctt aatgactgta
    25501 cttggaacag gcttgctctc tcttcttgga ttaggcttcc tggcaaaacg caaaagaaag
    25561 caataactaa cacataatca ttagtaatcc attcattatc catttacaag ttatcataaa
    25621 aaagccttat cattccttga ctggtatgat aaggcttttt gtttacccta tatagctcta
    25681 cccttactcc aaaaatcact taaccctagg aaaaggctga ctatcatttt tggccaaaaa
    25741 aagacagaca ccaattcatg atgtctgtct caaaaccaat cccttttagg gtcagtcctt
    25801 aattacttat taaaatgaac ttggatctac cttgataccc acaccttgtg tagttgtgat
    25861 agatacgtta gtcatgtaag taccctttgc agtagctggc ttagccttaa ccattacctc
    25921 atggaaagcc ttaaagtttt caaccaactt gtcagcgtca aatgatactt taccaatgat
    25981 agcttgtacg ttacctgctt tatcagcacg ataggtaatt ttaccaccct tagactcttc
    26041 aaccgcctta gcaacgtcca ttgttactgt accagtttta gggtttggca tcaagttacg
    26101 aggtccaagg acacgtccaa gacgtccaac aatagccatc atatctggtg ttgcaataac
    26161 aacatcaaaa tcaagccagc cgccattgat cttagcaaca aggtcatctt caccaacgaa
    26221 gtctgcacca gctgcctttg cttcttcagc ttttgctcca cgagcaaaaa caaggacacg
    26281 ctgagtttta ccagttccgt ttggcaacac catcgcacca cgaatttgtt ggtctgcctt
    26341 gcgaacgtcg atgtttaagt tataagcaac ttctacagaa gcgtcaaatt ttgcgaagtt
    26401 agtttctttt gcgagtgcta cagcttcctc tacactgtat gcctttgtgc tgtccacttt
    26461 ttcaagtgct gcacgcattt gtttgctttt tttagccatt tttatcttct ccttgtaatg
    26521 tggtcatatc gatttgattt aaaaatctcc cacgtcactc atctctatga tgaagtcttg
    26581 cgggtaataa gggcaggttg ctgattaatc agtaacggtg aatcccatag aacgagcagt
    26641 accttcaatc atacgcattg cagcttcaat gtttgcagcg tttaaatctg gcatcttagt
    26701 ttcagcaatt tcttgtactt gtgcacgagt aactgtcgca actttagttt tgttaggtgt
    26761 acctgatcct ttttcaacac ctgcagcctt ctttaaaaga acagcagctg gtggtgtctt
    26821 tgtgatgaaa tcaaatgatt tgtcttcgta aactgagata acaaccggga taatcatacc
    26881 agcctgatca gctgtacgag cattaaattc cttagtgaat cccatgatgt tgatacctgc
    26941 ttgaccaaga gctggtccaa ctggtggagc tggtgtcgct ttaccagcag ggatttgaag
    27001 ttttacaagt ttttcgactt ttttagccat ttttaaaaat cctcctgttg tggttttggc
    27061 ggtaattcac gatttttacc tcccacaggt atgctagagc ataccttacc attatacctt
    27121 attagacaga taaatcaagt cattttcaca aaaatgttac cgcaaatagc agatgtctcc
    27181 tatggcacta gcagtacaag catgtgaggc ttccaaggag ccgcttctag ttgactttta
    27241 agcgtttttt tattataaca aagctatgca taagaaagtt acgatcaaag atgtcgcacg
    27301 cgaggcggga gtttctgtgg ctactgtctc ctatgtcatc aataacagag aagatcaaaa
    27361 aattagccct gaaacgcgca ataaagtgct gcaaatgatt aatcttttaa attatcggcc
    27421 aaaccaagcc gcaaaatcac tcgtgacaca aaaaagacag ctaatcgccc tttactacaa
    27481 agagcacagc tctgttttaa aaagagcaga gcagcttcac tttatcaccc agctatctgc
    27541 ctttctttac acaaagcact atcacttgat ttgccttaat caagaataca tcggaaaata
    27601 tgatgtagca gatgtcattc tcaccctaga ggtcaccaaa gaggaatttt acaagatcgg
    27661 aaatagcaac tttgttcctt tgattgctat tgatagtatt attgatgatc ccttattttt
    27721 ccagattaat agtgaccctc atctcctgtt caataaagcc agtgcttatt ttgcagggga
    27781 gccctttgaa ctggttagcc tgcctattca aaaccaagaa atcactcaag gactcgctca
    27841 acagtttgat aacatttgct ggattcactc tatttgcgac atcgaaagcg tgtctaaggg
    27901 gaatattcta gttattgatg atactgtcaa tcatattctt agtaagcaca agaacaaact
    27961 atacctgcca agtatctcag aagctaagct tctgaagctt tttcaggcta ttgagtgggc
    28021 ttccaaaaga gaagcaatca acaatcataa tattttggtt taaccatgat aagagcttag
    28081 caacaagctt gctgctaagc tctttttgtt ggtcaagagg ccaactttat ttaggtatca
    28141 gtcagtgtgc cagctctttt agccactaaa agcaggaatt agtttacaag tctaccaatt
    28201 gggtataaaa tagacttatg atcatctaca aattaacagc cttagccttt attatcctga
    28261 ctcccttatt ctctatgata atgatatccc tattgagact gggacgaaga ggccttaaat
    28321 ttcctgattt agccttacca ctttttgttt ttgaaattgt tattgtatca ggaaaatttt
    28381 tcacccatca tttactacct tattacctga ttgttatgtc cttgttggcc attgttatgg
    28441 cactcttact gattatcaga atccagcagt tttcttaccg ccgatttttc aaactatttt
    28501 ggcgagtagg ctttttagtc acactactct tttacctgat gctagttggt cttattttta
    28561 tcgtttagtg ccttaccaga catggcttca agcctagcag tctgaatctg ccaattaact
    28621 ctagcactat cactcaaaag gaagctgtct ttgaactttc tgcttgagtg ggactttttt
    28681 caaagcaatc aatccatatc aaaccagcat tagagcatgc ggcttgatac ggattgattg
    28741 ctttaagaac tgttgtaaaa tatcaaaaat tcagttttta ataaagtcca ttagctattt
    28801 ctacactaaa tatcatttaa gaaaacagag gctaataact agagttcact ataacctaaa
    28861 atcaccaata cctccgatta acttaattta accaaactac tgtatatacc aaagtttttt
    28921 acgtgtcatt ataatacgtt cagataaatc atctaatgca cgatctttgt tgagaccaac
    28981 atcatattga atacccatta atctatctag aaactcaaga cgatatttct tcataatatt
    29041 tcgtgagtgt ccttctggaa aatgctcatc aataagcgaa cttacaatct caactttatt
    29101 actaatttta aaatagcgac ttttcaaaga ttgtaattct tctttaattg ctcttaattt
    29161 agaaaaacta tctgctccat aaaccttagc ttccatttca ttagcctcag aataacttag
    29221 ttttattgtt gcaataaaat ttctaagtac ttccttctct tttttaagct ccctttctgt
    29281 cggactcatt ctatagtaat attgacgcca acgatattga gaagcgttga ctttttgatc
    29341 acttatagtc aaaatagtca atgctactac actaaagaaa aatattcttt tcgtttgcag
    29401 tttctcctat acttcataat gtactatttg tatataaaca caacataacc aagcattagt
    29461 atatcagaaa actttcttaa atatgtgata ttagctaatc tttttttaaa actctctata
    29521 tattaaggta ttatggacat attgacttag cagattagat ctgccaatta gctctagcac
    29581 tatcactcaa aatgaagctg tctttgagtt ttctgcttga gtgggacttt ttcaaagcag
    29641 catatcaaaa acccgtatca agccacatgg ttaagcttag cttggtacgg gtttgtttta
    29701 tgatgagcct ttagatgagc tcttttttaa ttggtttgca gtacctttct tggcttagtc
    29761 ccctcagctg gaccaatgac accggcctct tctaattcgt ccattagtcg agttgctcgg
    29821 ttaaagccaa ccgatagacg cctttggagc atcgaggcgc ttgccttttg cgtttccaat
    29881 acaagagcct ttgcttcctc aaaaagggga tcaccctcag gagctccgct gctgccataa
    29941 tcagagtcac taacctcacc cggatcaaaa taatcatcat aatcagcctc tgcctgctcc
    30001 ttgataaagc taacaatgcg ctcaacatca tcatctgaaa taaaggagcc ttgcagacgc
    30061 acagggtgat tctcatcaat cggcttaaag agcatgtccc cgcgaccaag cagcttttca
    30121 gcgccatttt catcaagaat ggtgcgacta tctgttcctg atgaaaccgc aaaggcaata
    30181 cgtgatggaa cattagcctt aatcaatcca gaaataacat caacagaagg tctctgagta
    30241 gctaaaatca tatggatacc tgctgcacgc gccttttgcc caagacgaat aatagcatcc
    30301 tcaacctcct tactagccac catcatcaaa tcagctagct catcaacaat aacaacaatc
    30361 atcggcaaag ggatttgctt ttgctcagat tgcttgttgt aggcttcaac cttggcattg
    30421 tagcctgcaa tatttcggac accgacctta ctgaacagct catagcgatt ttccatctca
    30481 tcaacaacct tctgaagcgc tttgcttgct ttacgagggt tggtgaccac cgggattaac
    30541 aggtgaggaa tgtcattata aacagacagc tcaaccattt tcggatcgac cattaggaat
    30601 ttgacctgat ccggtctagc cttcattaaa atactggaga taataccgtt gactgcaaca
    30661 gatttccctg atcctgttga gccagccacc agcaaatgag gcatgcgggt caaatcaaag
    30721 cttctggcac taccgttgac agccttacca agaggaattt ccaataattt gtcatcagat
    30781 gtgttggatt gctcccaaag ctcgcggaaa gaaaccgttg caacctctga atttggtacc
    30841 tctataccca caagggattt gccagggatc ggagcttcaa tccgtacgtc cttggctgcc
    30901 aaggccaagg ccaagtcatc agctaaattg gaaatgcgat tcacacgaac accaacagcc
    30961 ggcttaacct cgtatttagt tacagatggc ccaatctctg cccgctccac cttgacgtca
    31021 attccaaagc ttctgaaggt atcctctaat accttgatat tttgacgaac aaggtacttt
    31081 tccttgaatt gatttttagg cttatcagca gcaaacagct ctatcgtcgg cagcttgtaa
    31141 agcagattgg tctttggcgt gaaatcgacc tccactgaca gctcctcatc atctgacagc
    31201 ggcgcctctc ctgcgattgc tgaagcaccc gttagagggg cttctggtac agactcctct
    31261 tcatctccaa atgcctcagg ctcatcatca gcagggtgtg agtcataggc cagaatttcc
    31321 ggctcaaaaa atgcttcaga ctccttctga tcagccatct ccatcaatag gtcttctggc
    31381 tctgctaaaa gctcacctgt ctcaggatta atcgcttgat tggccagata ttcttgctcc
    31441 tccaaggcct ctcttgctag acgctcctct tcagccagca atcgttgctt ttctcgctca
    31501 acaaaccgct tttccttgtt ttcttgatag gccagggata gcttttcaaa aagcgtctta
    31561 acaaaatgac tgacgtcata aatatcccaa ggggtcatta aaaacaagcc cagcaggata
    31621 aacaaaaaac caataaaata agagccaata ttagaaaaca agaaggaaat aggcttgtac
    31681 agcatggccc caagcatacc accaccaaca aactcgctaa ccttaaaggc tagcaggtca
    31741 ttggtgatta gctggatagt cccagcaaca atagcctgat gagctagctg aggcaatgag
    31801 aaaagatagg catgccattc aaccagaagc cctaaaaaca agatgataaa gccagcgata
    31861 aggccatctt tttgcctgag ccacttgaag aaaaagaggt aaaaaaggac cgccaacatc
    31921 aagagattgg ctaagtcgcc aaccataaag cgaataagat tatataaggt aaccccaagc
    31981 gcacctaagc gaagcatggc aaaaacaagc aataaagcgc aggagaaaga agcaatcatt
    32041 ctcttaatag ccttttgctt ttcaagctct gcctttgtta aacgtctctt agggggattt
    32101 ttttgtcgtt gagttcttct agccatagcc ttattataac attttttaat cgttatgaaa
    32161 gatgacatta aaattctcaa taaatagatg aagctgcttg attttatgct ataatgtcaa
    32221 tcataagaac aaataggagt tgaagatgga aaaagaattt aacaccttga cctatggtaa
    32281 gcttcccctg caaattgata tggggcatgg caagctaatt cccaaaggag ttgaagtcaa
    32341 ggctatcgtt gatatgcaga ccgggcaagt caccttcaag gtttctcagg aggacttaga
    32401 gaagcttaga aatagttaaa aaatagactt cgtctcaatg ccctttagct ttattttcca
    32461 agtcatttta tgttaaaata aaagaaattg ttctaaggag tacacatgaa aaaactacta
    32521 tcttttggct taatcggtct tgctttgctt agcttaagtg gctgtgagtc cattgatcgt
    32581 gctattaaag gtgatgaata cgtcgatgaa aaaatcgcta gagaggaaag cgagacagca
    32641 gcaaaggctt atgaagcaaa aatcaaaaaa gcactcaagg ctgacgctga tcagtttcca
    32701 caattaaata aagaagtcga caaagacgaa gctaaggtca ttatcaaaac taatcagggc
    32761 gatatcaccc tcaagctctt ccccaagtat gcaccgcttg ctgttgaaaa ctttttaaca
    32821 cacgccaagg aaggctatta cgacaaactt ttgttccatc gggtgattaa taactttatg
    32881 attcaaaccg gtgatccaaa gggagatgga tctggcggag aatccatttg gaagggcaag
    32941 gacagcaaaa aagatgcggg acaaggcttt gctaatgaaa tctcaccatt tttatataac
    33001 attcgagggg ctcttgctat ggcaaatgcc ggtgcagata ctaatggcag ccagttcttc
    33061 atcaatcaaa gcaagctcaa ccaagccaag gccttatcaa ttgataatta ctctaagcca
    33121 atcattgact cctacgaaga agggggtaat cctagcctag atggtggcta taccgttttt
    33181 ggtcaggtta ttgagggtat ggatatcgtt gataaaatag ctgccagccc agtcggccca
    33241 aatgacaaac caatagagaa catcactatt aatgctattg acattgttaa ggattactcc
    33301 tttaaaaaat agcctctaag ctacaacaac aataaaacga ccagctcctt atcggaaaag
    33361 ccaccgattc aagagctggt cgtgattttt tgctatcaat taaataaaga agctagccta
    33421 ttgatcatat cattagcagc tatccattca cagccagcta tggtttacta ggaatgcttt
    33481 ttaaagtagc cctgcttagg cgaaacaaag aagctaatca gaaacaccac agccgaggtc
    33541 aaaacaatgc ttgagcctgc tgcaatatta aaggtgtagc ccaaatagag ccccaacaca
    33601 gaggtcatag ctcccaagca tgaggagata accagcatta cctttaggct gttagcatac
    33661 aaatacgctg tagccgctgg cgtaatcagc atcgccacaa tcaaaatggt accaacactt
    33721 tgcatagcag tcaccgaaac caaggtcaac aaaatcatca acagataatg ataagcagtg
    33781 accttcattc ccatagacct tgctagcaca ggatcaaagg aggtaatgag taattcctta
    33841 aagaagagga caataatagc caaaacaaaa accgaaacaa tgatcgtaat ccatttgtca
    33901 ctgtcttgca ctgctaggat atttccaaag aggatatgaa aaagatccgt tgagctatta
    33961 gcaatcccaa tcagaataac ccctaaggca agaaaagagc taaaggttat ccctattgct
    34021 gtgtctccct tgataacaga gttttccttg atgtaggtaa tgataacaga ggctagcaag
    34081 ccaaagacaa tagcccctac aaaaaaatta atccctaaaa taaaggacaa ggctactcct
    34141 ggcaaaacag cgtgagaaat cgcatcaccc attaatgaca tggacctaag gataataaag
    34201 cagcctactg ctcctgatac aataccaata acaacggctg taataagggc attttgtaaa
    34261 aaatgatagg acatcaggcc ctcaaaaaac ttcaaataca tttaaaacat tccctttcct
    34321 aagaatagat gatcaccata ggcctttgat agggtttcaa cagtgaacac ctcatcaaca
    34381 gatccataag cgatcagctc tttgttcaat accactaact catcaaagta atgctctacc
    34441 ttgcttaaat cgtgatgaac aattaaaatc gttttgcctg cttttttcaa gtccttgagc
    34501 aggtcaatga tgattttttc actaaccgaa tcaatcccaa caaagggctc atcaagaaaa
    34561 atatagtctg actcctgaat caagcatcta gctactagca tacgctgaaa ctgaccacca
    34621 gaaagagatt ttatcggacg attaccaaag ccagcaagcc caacctgctc tagcagctgg
    34681 tcaacctgat catattcttt ttttccgaca cgacgaaaaa gccctagcct agtgtaggtc
    34741 cctaatgaga cgcactcctt caccgtaatt ggaaagttgt agtcaatcat gctgcgctgc
    34801 tctacataag caatcgtatg ccccagcctt cgaccgtcct tttgatcaac agttacttgg
    34861 ccactataat ctaaaagatt gagcatagcc ttcatcaagg ttgattttcc tgcaccattt
    34921 ggcccgataa tcccaacgat agctggtcct ttgatttgta gtgagatatt gtctaaggct
    34981 tttacgttac cgttatagct aaccgaaaga ttttgcgtat caatcatttt ttctccttaa
    35041 tacaaacaaa gcacaacacc agaagctgct gtgctttatt gttatattat tttgctaagc
    35101 cttcagaaat tttatcaagg ttccatttca tcatggcata gtagctgtct ccatcttggc
    35161 cttttttggc tacagagtca gtaaagattt ctgcatagat cggaatacca ctgtccttag
    35221 aaacagtctc cattggacgt ctgtcaacac ttgactcaac aaaaagcgct gatggcttaa
    35281 cgtctttcaa tttttcgatc aatgatgaaa tttgatccgg agttccttct tcttcagtgt
    35341 tgatttccca gatgtaggct gatgggacac cgtaagcttt tgagaagtat ttgaagcagc
    35401 cttcacttgt gacgattagc tttttattgt cagcaatagc atcaaatttt gattttgctt
    35461 ccttatcaag cttctctagc ttctcaacgt aagcttttag gttgttttca taggtttcct
    35521 tgtttttagg gtctttagcg atcaattgct ttgcaatatt ttttgaatag ataaccccat
    35581 tttcaagatt caaccaagca tgagggtctt ccttgccttt ttcactttca ccttctaggt
    35641 aaatcacatc aataccatca gatacagcga agtagtcctt gtccttttcc ttcttagcat
    35701 tttttacaag ctttgtaaac caagcctgtc cgccgtcttc aaggttaata ccgttataga
    35761 gaataagatc ggcattgctg gtcttctcaa cgtcttctgg caatggctca tactcatgcg
    35821 gatcttgacc aatcggcaca atgctgtgca agtcaatctt gtcacctgca atatttttag
    35881 tcatgtcagc aataatggaa ttggtaacca caaccttgag cttgtcactc ttagcttcct
    35941 tgtttccacc attagagcag gcaaccagca tgaaaacagc caaaaaagca ctcaaggcga
    36001 ggctaagttt ctttttcatc agttatctcc ttaggatcta ttat
//
LOCUS       DARYMD010000020        35529 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYMD010000020 DARYMD010000000
VERSION     DARYMD010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35529
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            9..82
                     /locus_tag="TU818_000896"
     tRNA            9..82
                     /locus_tag="TU818_000896"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Met,seq:cat)
     gene            103..176
                     /locus_tag="TU818_000897"
     tRNA            103..176
                     /locus_tag="TU818_000897"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Ile,seq:cat)
     gene            184..273
                     /locus_tag="TU818_000898"
     tRNA            184..273
                     /locus_tag="TU818_000898"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:Ser,seq:tga)
     gene            285..358
                     /locus_tag="TU818_000899"
     tRNA            285..358
                     /locus_tag="TU818_000899"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:319..321,aa:Met,seq:cat)
     gene            383..455
                     /locus_tag="TU818_000900"
     tRNA            383..455
                     /locus_tag="TU818_000900"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:416..418,aa:Phe,seq:gaa)
     gene            461..531
                     /locus_tag="TU818_000901"
     tRNA            461..531
                     /locus_tag="TU818_000901"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:493..495,aa:Gly,seq:tcc)
     gene            561..634
                     /locus_tag="TU818_000902"
     tRNA            561..634
                     /locus_tag="TU818_000902"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:595..597,aa:Ile,seq:gat)
     gene            644..731
                     /locus_tag="TU818_000903"
     tRNA            644..731
                     /locus_tag="TU818_000903"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:678..680,aa:Ser,seq:gct)
     gene            790..1605
                     /locus_tag="TU818_000904"
     CDS             790..1605
                     /locus_tag="TU818_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL0923734.1"
                     /translation="MKKLNLSRLFFWLTSLALLALTLVLLFRVAISPYLSMIIRNPVT
                     KIDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQLQVDKLKSENRELK
                     ELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVTSELGLIGRVTAVS
                     QSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVASEFNSNDSISLDAK
                     VYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLDYVLVVGKE"
     gene            1608..2111
                     /gene="mreD"
                     /locus_tag="TU818_000905"
     CDS             1608..2111
                     /gene="mreD"
                     /locus_tag="TU818_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL0923735.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNLLILFCFRK
                     LILSQFY"
     gene            2207..3385
                     /locus_tag="TU818_000906"
     CDS             2207..3385
                     /locus_tag="TU818_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0923736.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            3490..4452
                     /locus_tag="TU818_000907"
     CDS             3490..4452
                     /locus_tag="TU818_000907"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL0923737.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            4812..5582
                     /gene="recO"
                     /locus_tag="TU818_000908"
     CDS             4812..5582
                     /gene="recO"
                     /locus_tag="TU818_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL0923738.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEVQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            5698..6705
                     /gene="plsX"
                     /locus_tag="TU818_000909"
     CDS             5698..6705
                     /gene="plsX"
                     /locus_tag="TU818_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL0923739.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            6698..6946
                     /locus_tag="TU818_000910"
     CDS             6698..6946
                     /locus_tag="TU818_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL0923740.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            7096..7806
                     /locus_tag="TU818_000911"
     CDS             7096..7806
                     /locus_tag="TU818_000911"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL0923741.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            7985..11725
                     /locus_tag="TU818_000912"
     CDS             7985..11725
                     /locus_tag="TU818_000912"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL0923742.1"
                     /translation="MNKRIFVEKKADFQIKAQVLLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAEDLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINAYSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRQAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGVVEALALAAFGNRLGACVTLPELDRSLTAQLGGFIFTSKEEITGVIKLG
                     QTTSDFTLVVNDVKLSGARLLKAFEGSLEQVYPTVFQQAGELKPVPVVTTALAAQFKE
                     KIAQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRMAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVRVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGNPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVGID"
     gene            11844..13301
                     /locus_tag="TU818_000913"
     CDS             11844..13301
                     /locus_tag="TU818_000913"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL0923743.1"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            13358..14380
                     /locus_tag="TU818_000914"
     CDS             13358..14380
                     /locus_tag="TU818_000914"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL0923744.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            14377..14934
                     /gene="purN"
                     /locus_tag="TU818_000915"
     CDS             14377..14934
                     /gene="purN"
                     /locus_tag="TU818_000915"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL0923745.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            15081..16628
                     /gene="purH"
                     /locus_tag="TU818_000916"
     CDS             15081..16628
                     /gene="purH"
                     /locus_tag="TU818_000916"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL0923746.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFT
                     GVRHFRH"
     gene            complement(17006..18160)
                     /locus_tag="TU818_000917"
     CDS             complement(17006..18160)
                     /locus_tag="TU818_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL0923747.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNVESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNHRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDSAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            18551..19813
                     /gene="purD"
                     /locus_tag="TU818_000918"
     CDS             18551..19813
                     /gene="purD"
                     /locus_tag="TU818_000918"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL0923748.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQSGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLAGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLSQSVVDTAVETIVKPVLKGMMTEGRPYLGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            20042..20530
                     /gene="purE"
                     /locus_tag="TU818_000919"
     CDS             20042..20530
                     /gene="purE"
                     /locus_tag="TU818_000919"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL0923749.1"
                     /translation="MKPIISIIMGSKSDWTTMQKTAEILDQFGLAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            20517..21590
                     /gene="purK"
                     /locus_tag="TU818_000920"
     CDS             20517..21590
                     /gene="purK"
                     /locus_tag="TU818_000920"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL0923750.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASRV
                     SEVIVAPYSDVEALRQLTERCDILTYEFENVDADALDTVVKEEQLPQGTELLRISQNR
                     IFEKDFLANKASAAVAPYKVVTSSLDLENLDFSKKYVLKTATGGYDGHGQVVIRSEAD
                     LEEANKLANTAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKSQAMAVKIAEQLNLSGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAVKLHAPAIMLNVLGQHMEQAQRYATENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQSDEVEEF"
     gene            21605..21829
                     /locus_tag="TU818_000921"
     CDS             21605..21829
                     /locus_tag="TU818_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL0923751.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENQESISEKMTELQKQYPND
                     YLAIYDLPLDTDLSQLAHYPSIAIGKGEFE"
     gene            22426..23718
                     /gene="purB"
                     /locus_tag="TU818_000922"
     CDS             22426..23718
                     /gene="purB"
                     /locus_tag="TU818_000922"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL0923752.1"
                     /translation="MLNRYSRPEMAKIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRANASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVAEKAKEHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMTRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPI
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFDRLGL"
     gene            24016..24929
                     /locus_tag="TU818_000923"
                     /pseudo
     CDS             24016..24929
                     /locus_tag="TU818_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            25012..25110
                     /locus_tag="TU818_000924"
     CDS             25012..25110
                     /locus_tag="TU818_000924"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL0923753.1"
                     /translation="MFKKYQYYLFLAALFLLHSAQLLSDIDWWRVG"
     gene            25144..26151
                     /gene="ruvB"
                     /locus_tag="TU818_000925"
     CDS             25144..26151
                     /gene="ruvB"
                     /locus_tag="TU818_000925"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL0923754.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGSPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            26392..26850
                     /locus_tag="TU818_000926"
     CDS             26392..26850
                     /locus_tag="TU818_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL0923755.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            26856..27257
                     /locus_tag="TU818_000927"
     CDS             26856..27257
                     /locus_tag="TU818_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923756.1"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            27254..29035
                     /locus_tag="TU818_000928"
     CDS             27254..29035
                     /locus_tag="TU818_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL0923757.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQTIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMVGTCLTAPRV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIYALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            29455..32097
                     /gene="adhE"
                     /locus_tag="TU818_000929"
                     /gene_synonym="adhC"
     CDS             29455..32097
                     /gene="adhE"
                     /locus_tag="TU818_000929"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL0923758.1"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDAIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            32592..33644
                     /locus_tag="TU818_000930"
     CDS             32592..33644
                     /locus_tag="TU818_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEL0923759.1"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIIAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
     gene            33847..34863
                     /gene="adhP"
                     /locus_tag="TU818_000931"
     CDS             33847..34863
                     /gene="adhP"
                     /locus_tag="TU818_000931"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL0923760.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
BASE COUNT        10120 a         6386 c         8374 g        10649 t
ORIGIN      
        1 agtttgatgg cggtgtagct cagctggcta gagcgtccgg ttcatacccg ggaggtcggg
       61 ggttcgatcc ccttcgccgc tattttgttt ttggattgtt ttggaccttt agctcaactg
      121 gttagagcac tcggctcata accgagcggt cgtaggttcg agtcctacaa ggtccataat
      181 ggtggaggat tacccaagtc cggctgaagg gaacggtctt gaaaaccgtc aggcgtgtaa
      241 cagcgtgcgt gggttcgaat cccacatcct cctttaaaga ttatcgcggg atggagcagt
      301 taggtagctc gtcgggctca taacccgaag gtcgtaggtt caaatcctgc tcccgcaatt
      361 atataaaaga tatatgctgg ttggctcggt agctcagttg gtagagcaat ggattgaagc
      421 tccatgtgtc ggcggttcga ttccgtctcg cgccatttta gcgggtgtag tttagtggta
      481 aaactacagc cttccaagct gttgtcgcga gttcgattct cgtcacccgc tttatagttt
      541 tcccaagcta tagtgtgctt gggcgcgtag ctcaggtggt tagagcgcac gcctgataag
      601 cgtgaggtcg gtggttcgag tccactcgtg cccatcatta tttggagaat tactcaagag
      661 gctgaagagg acggtttgct aaatcgttag gtcgggtaac tggcgcaagg gttcgaatcc
      721 cttattctcc gtattgtaaa ggtgattatc atactgataa tcgttttttt atttttagag
      781 gtgattttat tgaaaaagct taacctatct cgtctctttt tttggttaac atcattagct
      841 ttactggctt tgaccttggt tcttcttttt agagtagcta tttctccata tttatcaatg
      901 attatccgaa atcccgttac aaaaattgat gctataatgt ctaagccttt tgctgttata
      961 aaggagggtg caaaggaatt agatagcttg atgtctgctt tttctgaaaa taagcattta
     1021 aaaaaggaac ttaggtccta taaattggat cagttacagg ttgacaagct aaaatctgaa
     1081 aatcgagagc tcaaggaact gttagggttg gattatggta ctgataatca atttgctgcc
     1141 agaatgatat caagaaatcc ttatagctgg aataaatcgc tggtcattga tagcggcaaa
     1201 agggaaatta aggagaagtc tttggttact tcagagcttg gacttattgg tcgtgttaca
     1261 gctgttagcc agtcatctgc tcatgttgaa ttgttaacat ctgggaagaa tattgagttg
     1321 ccgattaaaa ttgtagataa ggataaggtg atttatggca atttaaaggc atttaaatca
     1381 gaaagtaaaa caatggttgc cagcgaattt aattctaatg actcaatatc attagatgct
     1441 aaggtttata caagtggatt agatggtgag actgtggcag atattcctgt tggaaaggtt
     1501 acgggcttta aaaatgctgc tgataagcta aagcgtcgta tttttataaa attgtatgct
     1561 gatactgata atcttgacta tgttcttgtt gttggaaaag agtgaatatg aaaaaatctt
     1621 cagagctatt agtccttttg ccttttcttt tattttttgt tgatgcacac gtgtcagacc
     1681 tgatcagctc aatgttacct gagggttact cggtagtatc acacctcttt ttactgtttt
     1741 tcctgatcct tatggtagcg tttagatcta agggagttat ttgtttcttc tctcttcttt
     1801 taggattatt gtttgattat tattattttg atcatatagg gattttgtct cttgccttgc
     1861 cttttggaac aatgatcgtt ctagggctat taaggttctt ttctggttcc attagtcagc
     1921 tacaattttt ccttttcttt actctttata tgtttcttgt agatgtatca agctttattt
     1981 tggcaaacag ctatcagtta actgatatga cttttcctta tgtaatgacg tttcagcttg
     2041 ctccgacttt aatcgtcaat ctccttattt tgttttgctt tagaaaatta atattaagtc
     2101 aattttattg attattacat acaactgtaa cagatgcgta acattaaacg cttgattttt
     2161 tgatagaata taatgtgtct tatcgaaaag gagtaatttt tttagtatga aaaaaagaat
     2221 tctatcagcg gttcttgtaa gcggtgtgac ccttggaaca gcaactacag tgggagcgga
     2281 tgatttagat tccaaaatag cgttgcaaaa ttcagttatt tctaatttaa ataaagaaca
     2341 aaaagctgcg caggatagaa tgaagacttt gcaaagtcag gttagctcat tacaatctga
     2401 acaagaaagg ttagtcgcta aaaatggtga gcttgaagcg cgatctgctc agtttgagca
     2461 ggagattcaa gtgcttgcca gtcaaattat tgctcgtaat gaaaagttaa aaggacaggc
     2521 tcgtagtgct caaaagggaa atacgttagg ttacctcaat gcacttttga attctaagtc
     2581 aatttctgac gttattactc gtttggttgc tattaataga gctgtgtcag ccaatgcaca
     2641 gatgttggaa aagcaaaagg ctgataagct ttctcttgaa gaaaagcaac aggaaaatca
     2701 agaagcgatt aatacaattg cttcaaatat tacagcaatt gaatcaaacc aagtagcttt
     2761 aaagactcaa caagcagatt tagaggttgc caaggtagat ttggcgcttc aattagcaac
     2821 tgctgaggac gagaaggcta gcttgattac ccgtaaagag gctgcagagc aggcagcagc
     2881 tcaagccaag gctcaggcag agcaggaagc agcagccaga gcagcacagg ctcaagctca
     2941 agcacagtct gtagcggcag ctcaagcagc agtgactcaa gccgtaccaa caccagctcc
     3001 agcgcaggca cagcctgttg tggcgccagc agctatggtt tcaacaccag cggtgtcgta
     3061 tgcctatgat ccttctaatc cgtaccctgt cggccaatgt acttggggag ttaaggcttt
     3121 agctccttgg gttggcaatt attggggaaa tggtggtcaa tgggcatcaa gtgcagcggc
     3181 agcaggtttc cgtgtaggtg caacaccaat ggttggctct gttgttgtat ggaatgatgg
     3241 tggctatggt cacgttgcct acgtaacagg tgttcagggt ggacagattc aagttatgga
     3301 agccaactat gctggaaatc aatctattgg caattatcgt ggttggttta gcccaggtgc
     3361 tgtatcgtat atttatccaa attagaaaat aagtaaaggt aagaatcagg attcttacct
     3421 ttttatttcc attgaaaaat tgattgaaaa gggttaaaat ggtataggat caaaactttg
     3481 gaggaaaaaa tgtcttattc tgatttaaag ctgtttgcat tatcgtcaaa caaggaatta
     3541 gcagaaaaag ttgctgctgc gatgggaatt caacttggga agtctacggt tcgccagttt
     3601 tcagatggtg agattcaggt caatattgag gaatcaatac gtggacacca tgtttttatt
     3661 ttgcagtcaa caagctcgcc tgttaatgat aacctaatgg aaattttaat tatggttgat
     3721 gctttaaagc gtgccagtgc tgagaaaatt tctgtggtaa tgccttatta tggctatgct
     3781 cgtcaggatc gtaaggctcg ttcgcgtgag cctattacct ctaaattagt cgctaatatg
     3841 ctagaggtgg caggtgttga tcgtttattg actgttgatt tacatgctgc gcagattcaa
     3901 ggcttctttg atattcctgt tgatcatctc atgggagcac ctttaattgc tgattatttt
     3961 gatcgtcatg gtctagtagg tgatgacgtt gttgttgtta gcccagatca tggtggtgtg
     4021 acgcgtgctc gtaagctggc acaattcctc caaacgccaa ttgctattat tgataagcgt
     4081 cgtagtgttg ataaaatgaa taccagtgag gtgatgaata tcattggtag tgttgaaggt
     4141 aaaaaatgta ttctgattga tgatatgatt gatactgctg gtaccatctg tcatgccgct
     4201 gatgcgcttg ctgaagcagg agcaacagca gtttacgcat catgtactca cccagtgctg
     4261 tcaggaccag ctcttgataa tattcaaaaa tcagcgattg aaaaattgat tgttttggat
     4321 acgatctatt taccagaaga aagactgatt gataagattg aacaaatctc tattgcagat
     4381 ttgattgcgg aagctatcat tcgtatccat gaaaaacgtc cattgtcacc cctatttgaa
     4441 ttagggaaat gataaggtta gcctgaggta gtaagcctta ggctttttta tgttttaaaa
     4501 ggctatttga ttaccaaagc agtgtttgat ttaacgccat agataggctt cactgtctta
     4561 tggtaggtgt tgagctatta tagcaaaaag tcatgtgtag gtgctgtgtt taaacagcta
     4621 gcctatgatt catatagtta tggctagtga ctgttgagct tcttattctc agagttgtta
     4681 cgagccttaa gtacagtgtt agtcatgcaa ttttcctgga ttttgggtat aatatagctg
     4741 tatttaaggt gttttaaagg tctagtaaga aaggcattat tactagctga gaagcttggt
     4801 tatggagata tatgcgtatt cagaggtcac ttggtattgt cttgtacaat aaaaactatc
     4861 gtgaagatga taagctcgta aaaatattta cagaagcggc gggcaagcgt atgtttttcg
     4921 tgaaacatat tggtcgttct aaactagctc ctgtggtcca gcctttaacg gctgctgatt
     4981 ttctattgaa aatcaatgat tcgagccttt cttatataga ggattataat caggtggagg
     5041 cttatcggca catcaatgaa gattttttta ggctatccta tgctagttat gtcttggctc
     5101 tggctgatgc ggctattcca gataatgagc ctgatcctca gttgtttgct tttttgaaaa
     5161 agactcttga tctgatggaa gaagggctag attatgacat tttaacgaat atctttgaag
     5221 tccagatttt ggatcgtttt ggggtgagaa tgaattttca tgattgtgtt ttttgtcaca
     5281 gaaccaatct gccttttgat ttttctcata agtattcagg tgtcctttgt ccgcagcatt
     5341 accatgagga tgagaggcga tatggcttgg atcccaatgt gatttatttg cttaatcgtt
     5401 ttcaaacgct taatattgat gagctaaaga ctatttctgt gaatactggt atgaaaaaaa
     5461 agcttcgtct ttttattgat gccttgtatg aggattatgt cggtattcgt ctaaaaagta
     5521 aggtttttat tgatgatttg gctaagtggg gagatattat gaaaaacaag cagggcttgt
     5581 gagctattca ggtgtggatt tgtcctttta tgggaattgt ctggggaata tgctataata
     5641 gttacgttat tctctaggat atttttcgtt aagaaaaata ggattaaagg agcaaaaatg
     5701 aagaaaattg caatagacgc tatgggtggt gattatgccc ctaaagctat tgttgagggt
     5761 gttaatcagg cgatagaatc cttttcagat attgaaattc agctttatgg cgatcaatca
     5821 aggattgagt cttacctagt taaatcagat cgtgtgtcca ttgttcatac agatgaaaaa
     5881 attaattctg atgatgagcc agcaaaggct attcgtcgta agaagaatgc ttctatggtt
     5941 ttagctgcaa gggcagttaa ggatggtcgg gctgatgcag ttctttcggc aggtaataca
     6001 ggcgccttgt tagctgctgg tttgtttatt attggtcgta tcaagggagt ggatcgtcct
     6061 ggtttgctgt caactctgcc aacggttgat ggttcaggct ttgacatgtt agatttgggt
     6121 gccaatgctg aaaacacagc agagcattta caccaatatg ctattttagg ctctttttat
     6181 gcaaaacatg tgcgtggtat tgccaagcct cggattggct tgcttaataa tggtactgag
     6241 gcaactaagg gtgattctct tcgcaaggag gtctataatt ttttagcttc agacagcagc
     6301 ctacagttta ttgggaatgt tgaggcaaga gatttgatgt ctggcgtggc agatgttgtg
     6361 gtagcagatg gctttacagg aaatgctgtt ttgaagtcga ttgaaggcac tgctatgagt
     6421 attatgggac aattgaaatc agctatagca gtaggtggtg ttaaggcaaa gtttggagct
     6481 cttttattga agagtagcct ttatgactta aaggatactt tagattattc cagtgcgggt
     6541 ggggctgtat tgtttggtct taaagcacct cttgtgaaat cacatggttc tagtgatgcc
     6601 aaggctattt ttcataccat taagcaggtt cgtacgatgc tagaaacaga tgtagttggc
     6661 caattagttg aggagttttc taaggagagt gatgtaaatg actgaggaag ttattttaga
     6721 gaaaatcatc gcattaatca agaagcaaag aagtcgtata gactttgaca ttacagaaaa
     6781 aacagcacta aaggatgatt taggagtaga ttcgattgaa ctggtagagt ttgttattaa
     6841 tatcgaagat gaatttggta ttgatattcc tgatgaagat gttgatggca tggtatctat
     6901 gggagatatg ctaaattatt tggtcaagcg tttaaaccaa agctaaatag ttttaaaaga
     6961 gcaccagctc tttttttgtt tccgaaaaaa cgaacattat aagtttattt tatattaaat
     7021 gtaaataaat gttgaatatt tagtatgttt gtggtattgt ttagatatta aatgcaaaga
     7081 aaggcgaaca aataagtgtc taatcaactc atttattcag gtaaggcaaa ggatatctat
     7141 gaaacagccg atgacgggat tgtcttaatc tcctacaagg atcaggtcac tatgctaaat
     7201 ggagcacata aggaaatgat tgaaggaaaa gggagcctta ataatcagat ttctgcctta
     7261 atctttgata ggctaaatag ggttggcgta tcaactcatt ttattaagca attatccgag
     7321 acagaacagt taaataaaag ggttgcgatt attcctttgg aggttgtttt acgaaacgtg
     7381 gccgctggct cattttcaaa gcgctttggt gttaaagaag gtcaggcttt ggacgagcca
     7441 attattgagc tttattacaa gaatgacgct ttagatgatc ctttcattaa tgatgagcat
     7501 gtcagctttt taaagcttgc gactgatgag cagatagcct acatcaaaca agagacgcat
     7561 cgtattaatg cttatttgaa ggagtggttt gctagtgttg ggttgacact ggttgatttt
     7621 aagctagaat ttggctttga taaggagggg atgcttatcc ttgctgatga gttttctccg
     7681 gataattgcc gcttgtggga taatgcgggc cgtcacatgg ataaggacgt ttttcgtcgt
     7741 cagcttggca gtttgacgca agcctatgag actgttttag aaaggctaag agcattggat
     7801 caataaagac cagcttattt gttgtcagtt aagaaaggga gctctttttt gtccgtcatg
     7861 taagaaaata aatcagttca gactatttga gctgctgtct aagaaaggct gtctgctatt
     7921 ggagaaaaga gtcaggctag ttcttatttt gggctggttt ctgattggac ttggtatatt
     7981 aactatgaat aaacgtattt ttgttgaaaa gaaggctgat tttcagatta aggcacaggt
     8041 cctgttaaag gaattgaaac atcagctgca gttaaagaca ctggttgatt tgcgtattgt
     8101 gcaggtttat gatgtgtttc atttggatca ggagctgctt ttaacagcta taaagcatgt
     8161 tttctctgag caggtcactg atcaggtatt gtcagaagaa gctttacaag cagatttaaa
     8221 aaggtatgcc ttttttgcga ttgaagctct gcctggacag tttgatcagc gtgcggcaag
     8281 ctctcaggaa gccttattgt tgttaggagc ctcaactgat gtgactgttt tgacctcaca
     8341 gctttatttg gtcaatcaag acattgctgc tgaagaatta gaagccttaa agcagtactt
     8401 gttaaatcca gtggattcta ggtttaagga catattagcc ggtcttgatg atcaggattt
     8461 ttcagtagca gataaagtga ttccaacgct tgatgttttt aatgattata cagcggaaga
     8521 tcttgctcgt tacaggtctg agcagggcct agcaatggaa gtggaggatc tgctgtttat
     8581 tcaggattat ttcaagacaa aggggcgagt gccaacagag actgaactaa gggttttgga
     8641 tacgtattgg tctgatcatt gtcgtcacac aacctttgaa acagagctaa aaacgcttga
     8701 tttttcagct tctcattttg aaaagcagct ccaagctacc tatgagacct accttgctat
     8761 gcgtgatgag ctaggtcgat ctgaaaggcc tcaaacgctt atggatatgg ctaccatttt
     8821 tggacgttat gaaagagcta atggtcgttt agaggatttg gaggtttcag atgaaatcaa
     8881 tgcttactca gtggaaattg aggtagatgt tgatggtgtc aaggagcctt ggctgctcat
     8941 gtttaaaaat gaaacacata atcacccaac ggaaattgaa ccctttgggg gtgctgcaac
     9001 ctgtattggt ggagctattc gtgatcctct gtcaggccgt tcctatgttt atcaagccat
     9061 gcggctttct ggtgcagggg acattacaag cccgctgtca gagactcgta agggcaaatt
     9121 accacagcag gttatttcga ggcaagcagc acatggttac tcgtcatatg gcaatcaaat
     9181 tgggctagcg actacttatg ttcgtgagta ttttcaccca ggctttgttg ccaaacgtat
     9241 ggagcttggt gcggtagttg gtgctgcacc caaggaaaat gtggttcgtg aaaagccaag
     9301 gacaggtgac gtggtggttt tgcttggtgg gaaaacagga cgtgatggta ttggtggtgc
     9361 gacaggatca tctaaggttc agacagttga gtctgtagaa acagctggtg cagaggtcca
     9421 aaaaggaaat gccattgagg agcgtaaaat ccaacgtctt tttcgtcgtg gcgatgtgac
     9481 acgcctcatc aagaagtcaa atgattttgg tgctggtggt gtttgtgtag ccattggcga
     9541 gcttgctgct ggtcttaaca ttaacttaga taagattcct ttaaaatatg ctgggctaaa
     9601 tggaacagaa attgccattt cagaatccca agagcgtatg gctgtcgtga tttgtccaaa
     9661 ggatttagag gcctttatga gcgcctgcca taaggaaaat atccatgctg ctgttgtggc
     9721 agctgtgaca gaaaaaccga atcttgttat gacctggaat gggcagacga ttgttgatat
     9781 tgaacgctca tttttagaga caaatggtgt gcgcgtgtct gttgctgcta aggttgttga
     9841 cagtggtgcg ccaataccag aagctcgtca aactactgct gagacacttg aagcagatac
     9901 cattgctgtc ttatcagacc tgaaccatgc tagtcaaaag ggtttgcaaa ccctgtttga
     9961 tagctcagtg ggtcgctcta cagtaataca tccgcttggt gggcgctatc aaatgacacc
    10021 tgttgaaggc tctgttcaga aattaccagt tcaacatgga gtgacaaaga cagtctctgt
    10081 tatcgctcaa ggctatcacc cttatatagc cgaatggtca ccttatcatg gtgctgctta
    10141 tgctgtaatt gaggcaactg ctcgtctggt cgcaacgggt agccattggc ataaggcacg
    10201 cttttcatat caggaatatt tccaaagaat ggataagcag gcagagcgct ttggtcaacc
    10261 ggtggcagcc ttgcttggag caattgaagc acaggtgcag cttggcttgc cttctattgg
    10321 aggtaaggat tcaatgtctg gtagctttga ggaattgaca gtgccgccga ccttggttgc
    10381 ctttggtgtg acgactgctc atgtagatca tatcctttca ccagaattta aagctgctgg
    10441 cgagaatatt tactatattc caggacaggc tatttcggaa gtgattgatt ttgagttgat
    10501 aaaatctaat tttatgactt ttgaggctat tcagaaaaag cataatatta gctcagcttc
    10561 ggctgttaaa tatggtggtg ttgttgaagc actggctctt gctgcctttg gtaatcggtt
    10621 aggggcttgt gtgacattac cagagcttga caggagctta acagctcagc ttggtggctt
    10681 tatctttaca tcaaaagagg aaatcacagg tgttatcaag cttggtcaaa ctaccagtga
    10741 ctttacattg gttgtcaatg atgtcaagct atctggagct cgtctcttaa aggcttttga
    10801 agggagcctg gagcaggttt acccgacggt atttcagcag gcaggtgaat tgaagcctgt
    10861 tcctgtagtg acaacagcac ttgctgctca gtttaaggaa aaaatagctc agccagttgt
    10921 ctatattcca gtttttccag gaactaactc agaatatgat tcggctaagg cctttgaaag
    10981 agagggtgca agggtgaact tggtgccttt tgttaccttg aatgaggcag ctattgacgc
    11041 ttcagttgac acgatggttg accatattca tcaagctcat attatcttcc ttgcaggtgg
    11101 tttttcagcg gcagatgagc cagatggttc agctaaattt attgttaata tcctgctgaa
    11161 tgagaaggtt cgaatggcga ttgatgcctt tattgaaaag ggtggtctga ttatcggtat
    11221 ttgtaatggc tttcaagctc tggtcaaatc agggctgctg ccatatggac gttttgaggc
    11281 ggtacatgag gctagtccaa ctctgtttta taatgatgcc aatcagcatg tggctaaaat
    11341 ggtagaaacg cgtattgcca ataccaattc tccttggctg gcaggtgtca gggtggggga
    11401 tattcatgct gttgcagtgt cacatggaga gggcaagctt gtggtaacag aaagagaatt
    11461 agcagagctt tgtaaaaatg gtcagatttt tagccagtat gttgaccttg atggtaatcc
    11521 aagcatggat agcaggtata atccaaatgg ctctgtcaac gctattgaag gtcttaccag
    11581 caaaaatggt cagattatcg gtaagatggg acattcagag cgctttgaag agggactttt
    11641 ccaaaatatt ccgggtaata aggatcaatg gttattccga agtgcggtgc attattttag
    11701 aggagaccat gtgggtattg actgaactgg gatatagcct tgtaatagct aagatagctg
    11761 ctattattgc tcagcctagc tgttagttct agcttagtta atgacacaat cataattaaa
    11821 agggcattag cccagaggta aagatgacat atgacgtaaa atctcttaat gaggaatgtg
    11881 gtgtttttgg gatttgggga cacccacatg ccgctcaagt gacttatttt gggcttcata
    11941 gcctacagca ccgcggccaa gagggagcag gtattatttc aaatgataat ggggagcttc
    12001 atcagcatcg tgatgtaggt ctcttgtcag aggtgtttaa ggattcatct gatctggaca
    12061 agctaaaggg acatgctgcc attggtcatg tgcggtatgc gactgctggg acggcttcca
    12121 ttaataatat tcagcccttt ttatatcgtt ttacagacgc tcaatttggc ttgtgccaca
    12181 atggtaattt gaccaatgct atgtcattga aaaaagcgtt agagagtgag ggagctattt
    12241 ttaatgcctc ttctgataca gaaattctaa tgcatttgat tcgtcgtagt catcacccag
    12301 aatttttagg aaaggtaaaa gaggcactca acactgttaa agggggcttt gcttacctgc
    12361 tgatgacaga gaaccagctg atagcagcgc ttgatccaaa cggctttagg ccgttgtcta
    12421 taggccgtat gaaaaatggg gcttgggtcg tctcaagtga gacctgtgcc tttgaagtgg
    12481 ttggtgctga gtgggttcgc gatgtgatgc caggtgaggt cattatcatt gatgatcagg
    12541 ggatcactta tgactgctat acgactacta cgcagctggc tatctgctct atggaatata
    12601 tttactttgc gcgtcctgat tcaaccattg ctggagtcaa tgttcacacc gctcgcaagc
    12661 gaatgggaaa gagactggct caggaatttc agcatgaggc tgatattgtg gttggtgtgc
    12721 caaattcctc attatcagca gcgatgggct ttgcagaagc atcaggcctg ccaaatgaaa
    12781 tgggattggt caagaatcaa tatacccaac gaacctttat ccaaccaact caggagcttc
    12841 gtgagcaggg agttcgaatg aaactttcag ctgtttcagg tgttgtcaag ggcaaaaggg
    12901 ttgtgatggt agatgattct attgtcagag ggacaacctc acgacgcatt gttaatttgc
    12961 tgcgtgaagc aggagctaca gaggttcatg tagcaattgg tagccctgag ctcaaatacc
    13021 cttgctttta tgggattgat attcagacaa gacgggagct gatttcagct aatcatactg
    13081 ctgctgaggt ctgtgatatt atcggtgctg atagcctgac ttatttgtca cttgatgggc
    13141 ttatcgaggc tattggactt gatacaaaag caccaaatgg tgggctttgt gtggcttatt
    13201 ttgacggtca gtatccaacg ccgctttatg attatgagga ggcttatctc aagagcttag
    13261 aagaaaaggt aagctttcac attgatcagg tgacgaagta gcgctttatg gctaacatag
    13321 aataaatgat ctaggcagct aaaataagga ggagaaaatg tctaaaaatg cttatgctca
    13381 atcaggtgtc gatgttgaag caggctatga gcttgttgag cgaataaaaa agcatgccga
    13441 gcgtagcaaa cgattgggtg ttatgggtgg tctaggaggc tttggtggtc tgtttgacct
    13501 gtcaaagact ggtgttaagg agcctgtttt ggtttcaggg acagatggcg tcggaacaaa
    13561 gctaatgctt gcaatccagt acgataagca tgacacgatt gggcaggatt gtgtggcaat
    13621 gtgtgtcaat gatattattg cagcaggtgc cgaacccctg tattttcttg attaccttgc
    13681 agcaggaaaa aatgagcctg ccaaattaga gcaggtgatt gcaggtattg ctgagggctg
    13741 tgttcaagca ggtgctgctc ttatcggtgg agaaactgct gagatgcctg gtatgtatgg
    13801 tcaagatgac tatgatcttg ccggttttgc ggttggtatt gctgagaaat ctcagctgat
    13861 tgatggttca agagtagctg agggagatca tctcctaggt ttggcatcaa gtggagttca
    13921 ttcaaatggt tattccttgg ttcgtcgtat ttttgccggt tatactggtg aggagctgct
    13981 tccagagctt gatggaaaaa agcttaagga ggtacttctt gagccaactc gtatttatgt
    14041 caaggctgtg ttaccactca ttaaaagcgg cttagtggca ggaatcgctc atattacggg
    14101 tggcggcttt attgaaaacc tacctcgtat gttttccaaa gaactagccg ctgaaattga
    14161 agaagccagc ttacctgtgc tgcccatttt taaagtcctt gagacatatg gtaagatcaa
    14221 tcatgaagaa atgtttgaga tttttaatat gggtattggc atggtgcttg ctgtcaagcc
    14281 tgagcacgtt gagcaggtga aggcctgtct tgatgagcct gtgtatgaca ttggtcgcgt
    14341 tgtgaccaga acagttgcta gtgtggtgat gaagccatga caagaattgc cgtttttgct
    14401 tctggtaatg gctccaattt tcaaacgatt gcagaacagt ttccggttgc ctttgttttt
    14461 tctgatcatt gcgatgctca tgttttaagt agagcctgtg ctttgggtgt tctgtcctac
    14521 agctttgaac taaaggactt tgagaataag caagcctatg agcagactct tgtggcattg
    14581 ctgcagcggc atcagattga tctcatcgtc cttgccggct atatgaaaat tgtgagtaca
    14641 accttacttg atgcttacga aggaaaaatc atcaacattc acccagctta tttgccagaa
    14701 tttccaggag cacatggtat tttagatgct tggcaagcag gtgttagtca gtcaggagtg
    14761 actgttcatt gggttgatag tggtattgat acaggaaaaa tcatcaaaca ggtacgagta
    14821 ccacgtttga gtgatgatac tcttgaaagc tttgaagcca gaattcatga agcagaatac
    14881 caattgtatc cagaggtact ggatagtctt ggagtagagc ggcttaaccg ctgattgtgt
    14941 aagattaata actattttcc ctattgtggc atttcgttta tcatagcagc tgcgctaatg
    15001 gtggctaaca aaggctagaa gacttgtttg atgatggcac tgctattgag gaaaatagac
    15061 ttttctaagg agaacttaaa atgactaaac gcgccttaat tagcgtatca gataaaagag
    15121 ggattgtgga ccttgctagg gagcttaagc atcttggctg ggatattata tcaacaggag
    15181 gaacaaggct tgctcttgaa gaggctggtg tagttactgt tgctattgac gatgtgacag
    15241 gctttcctga aatgatggac ggacgggtaa aaacgctgca ccctctcatt catggtggct
    15301 tacttgctcg tcgtgacatt gagcaccact tacaggcagc aaagcaaaac aggattgaat
    15361 taatagacct tgttgttgtt aacctttatc ccttcaaaga aaccatttgc cgtccagatg
    15421 tcacttatga tgtcgctgtt gatatggttg atattggtgg tccttcactg ctgcgttcag
    15481 cggctaaaaa tcatgctagt gttacggtag tggttgatcc gacagattat ccgctcgttt
    15541 taggagagtt ggctagcact ggcagtacaa gttaccaaac ccgtcaaagc ttagcagcta
    15601 aagcttttcg ccatactgca gcctatgatg cagtgattgc agattatttt acaagacaag
    15661 caggtgagac aaagcctgaa aagctcacgc ttacctatga tttgaagcaa agcatgcgtt
    15721 acggtgaaaa tcctcaacag gctgcagatt tttaccaaag agcgctccca acaacctatt
    15781 caattgcttc agccaagcag ctaaatggaa aagagctatc attcaacaat attcgtgatg
    15841 cagatgctgc gattcgtatt attcgtgatt ttaaggagcg tccaaccgtt gtagcactca
    15901 agcatatgaa tccatgtggt attggtcagg cagatgatat tgagacagct tgggattttg
    15961 cttatgcagc tgatccggtg tctatctttg gtggtattgt tgtcctaaat cgtgaggtgg
    16021 atctagcgac agcggagaag cttcatgcta tttttcttga attgatcatt gcaccaggct
    16081 attccaaaga agcgctagct gttctcaccc ataaaaagaa gcacttgcga attcttgaat
    16141 tgccatttgc tgctcaggag gctagtgaaa tagaagcaga atatacagga gttcttggtg
    16201 gtctactagt gcaaaatcaa gatgttgtca cagagtctcc agcggattgg atagtggtga
    16261 caaagcgtca gccaaatgaa caggaaatgg ctgctctagc atttgcttgg aaaaccatca
    16321 aatatgtcaa gtctaatgcg attgtcattg ctaatgatca tatgactttg ggcgttggtc
    16381 cagggcaaac aaaccgaata gcctctattc gtattgctat tgcgcaagca acggggcagc
    16441 ttgagggagc agttcttgct agcgatgcct tcttcccatt tgcagacagc attgaagaaa
    16501 ttgctgccgc tggtatcaag gctattatcc agcctggagg ctctattcgt gattcagaat
    16561 ctattgcagc tgccaatcag catggtataa ccatgatttt cacaggtgtg aggcatttta
    16621 gacattaata aagtaaaaag agactggagc caaaagagtt gcactttaga aattcttggt
    16681 taatatactt tattacctag ttggattcat taaaaagcga acaagtctag ttttcataat
    16741 ctcagaaaac tagacttgtt tgcttgtttt atttggtggt catactattg tttcagcctc
    16801 tttttactat gactaataca agaatttatg aaggaacaag gctttatttt ttgttgtggt
    16861 aacagtgacc agatccgtta tcaatcagta tttgagtatt ttgagctcta gatgcatcac
    16921 ttagatagga tattgcaaag gatacagctg ctgcatgtat taggaaagca ttatcataaa
    16981 aggctttttc gttagcctaa aggttttaga ccttctttgc cttatctatt gttaaccatg
    17041 ttccacgtga acccatttgc acgtaaatcc ccttgctagg ctgatcaacc tttagaacct
    17101 tataggttcc tgaaacgaca aaataatcac ccacctgcaa aatctgattt ccagcaatac
    17161 gtcctttatg gtccgtttcg tggagtggag ctgagtctat ccagtttaag gaggttggct
    17221 ctccaccggc taattcactg cttgcaatca tgttctgagc gacctgatcg acccgaaaaa
    17281 caccaggaaa ggctacagta tctccaacct tgataggagt ggtcgccaca ggctttggtt
    17341 tatctataga ggcttgacta tgttgctgag gctgaaccgg caatttgtga attggaatgt
    17401 agcgatgatt tcctgaatga ccgatatagc tgagccattc atagccatca gcgacaaggg
    17461 tttgatcata gtgcactaac tgtccagtat gatagtaagc taaatcagga cttgctaatg
    17521 tagcttcagc ctttatagga ctttggcttg aaaaataata ggtaccactt ttagctagac
    17581 gagttgatcc tgcttgagaa gcatgtaaca tttgtgtgtg gctggtagag ttgtgatcca
    17641 gatccttgaa gtgaatgtaa ccacttacct gatgcttatg aatctgtcgt ttatgatact
    17701 tttcaggtcc ctgtccggca ttatagttgt attcctcaat aataacagtg tcaccattga
    17761 cctctgctac ccaggcgacg tgtccatata gggcatgtga ctggttaaag cccttatccc
    17821 accaagcaac agcaccaact ctaggtgtat gatcaacatg atagccttgg tgtttagcta
    17881 tacgtcccca gctttcaaca ttaccatagc ctctaggcag gctgaatcca tttgaggaat
    17941 gcagtcggaa tgctacaaaa gaagtgcatt gacgtaagta catgttccaa ggatcagctc
    18001 cgaagccctg tttccactta cttggatagt tatcccctaa aacagcagcg tgtacgatac
    18061 ctgactgacc ttgtgaaatc gttgttgtgg cagaggatat tgcaccatta ccacctaaaa
    18121 ggattgctcc tgaagctaac aattgataga cttttttcat taattacctc ctgtaactta
    18181 ctattcgcaa gaaagaggac aaaaatgtcc ttgatttaaa aaaatgtaag gaaaaatatt
    18241 ttagcctcaa aatactgttg gtgctcccta gcttccaaga gccaataggc aagcccatct
    18301 ccagcttgcc tgctccctgt agctaaaagc aatttatagt aacactagca cctcatctga
    18361 agaggcaggc tgtggtaatt aatgccaata atctgtaaaa agagacagca ggtatggtta
    18421 tatgagctat gatggttata ttctataaag cttatttttt agcttcgggc tttctttggt
    18481 gattagttat ttatataaac gaacaattat gctaaaatat gtttataaaa ttcgtgttat
    18541 gaggtgtgtg atgaagcttt tagttatcgg ttcaggtggt cgtgaacatg cgattgctaa
    18601 gaaattgtta gagtcaaaag gcgttgaaca ggtttttgtg gcacctggca atgatggcat
    18661 gacccttgat ggcatagaac gggtagatat tgacatttcc gaacattctg ctttgattgc
    18721 ttttgcaaag accaatcata tagcctggac ctttgtggga ccagatgacg cattagcggc
    18781 tggtatcgtt gatgagttta accagtctgg cttgaaagcc tttgggccct ctcgtttagc
    18841 agcggagctg gagtggtcaa aggactttgc taagcaaatc atggtcaaat acggtattcc
    18901 aacagcagcc tatggcacat tttctgattt tgcaaaagcc aaggcctaca tcgaggaaaa
    18961 gggcgcgcca attgtggtta aagcagatgg tttggcgcta ggaaagggtg ttgtcgtagc
    19021 agagactgta gagcaggcag ttgaggcggc gcgtgacatg ctcttggata ataaatttgg
    19081 tgattcaggt gcgcgcgtgg tgattgagga atttttagct ggtgaagagt tctctctctt
    19141 tgcctttgtg aatggcgatc agttttacct catgccgaca gcgcaggacc acaagcgggc
    19201 tcttgatggt gacaaggggc caaatacagg tggtatgggg gcttatgcac cagtgcctca
    19261 tctttctcaa agtgtggtgg atacagcagt tgagaccatt gtcaagcctg ttctaaaagg
    19321 gatgatgaca gaggggcgtc cctatcttgg aatcctttac tgtggcttga ttttgacaga
    19381 agatggacca aaagtgattg aattcaatgc tcgctttggt gatcctgaga ctcaggttat
    19441 ccttcctcgc ctgacctctg attttgcaca gaacattacc gatatattag agggcaacac
    19501 agctaatatc acatggtcag acgagggagt gacgctcggc gttgtccttg cttcaaacgg
    19561 ttatccgctt gcttacaaga aaggtgtgct tctgccagca aagaccactg gcgacatcat
    19621 tacctactac gcaggggtta agcttgcgga aaatggcaaa gcactgctgt caaatggtgg
    19681 acgtgtctat atgctggtca ccacagcagt taccgtccca gctgcgcaag aaaaaatcta
    19741 taccgaactt gctcagcaaa ataccgaagg attattctac cgaaacgata ttggaagaaa
    19801 agcagtaaaa taaattagcg ctagctcaag ctaccgaagg tcgctatgat gacaatgact
    19861 tattatcggt gagcaaaagc gagcctaaca cgatactttt cgccgtagcg caaagagtga
    19921 caaggtcact cgggggaact tgaaagacct tgggctttca agttagtcat gagacaccta
    19981 tggtggctgt tgacgccccc ccccacttaa gaaaagtatc aaaaaccttt aaggagaaag
    20041 tatgaaacca attatctcta tcatcatggg ctccaaatct gactggacca ccatgcaaaa
    20101 aaccgccgaa atcctcgacc agtttggcct tgcctacgaa aaaaaagtgg tctctgccca
    20161 ccgcacgccg gatctcatgt tcacatacgc tgagaaagca cgcgaacgtg gcattaaaat
    20221 catcatcgct ggtgctggcg gagcagccca tctccctgga atggtcgctg caaagacgac
    20281 acttcctgtt atcggcgtac ctgtcaaatc gcgtgctctt agtggtcttg attcgctgta
    20341 ttcaattgtg cagatgccag gtggtgtgcc tgtggcaact atggccattg gagaggcagg
    20401 agcaaccaat gcagcactga ctgctcttcg gatcctttca attgaggatg aaacaatcgc
    20461 agagcagctc agccatttcc acaaagagca aggacggatc gcagaggagt caacccatga
    20521 actcaactaa aacaattgga attatcggag gtggtcagct gggacagatg atggcgattt
    20581 ctgccattta tatggggcat aaggtcatta cactggatcc agcagcggat tgcccagcct
    20641 cgcgcgtgag tgaggttatc gtggcgcctt atagtgatgt ggaggcgctg cgtcaattga
    20701 ccgagcgctg tgatattttg acctatgaat ttgaaaatgt ggacgctgac gcccttgata
    20761 cagtggtaaa ggaggagcag ctgcctcaag gaacagagtt acttcggatc tcgcagaatc
    20821 gtatttttga aaaagatttt ttagccaata aagcaagcgc ggcagtggca ccctacaagg
    20881 ttgtaacctc tagcctcgac ttggaaaacc ttgacttttc gaaaaaatac gtcctcaaga
    20941 cagcgacagg tggctatgat ggacacggtc aagtcgttat tcgctccgaa gcagaccttg
    21001 aagaggctaa taagttggct aacactgccg agtgcgtctt ggaagaattt gtcagctttg
    21061 accgagagat ttccgttatt gtatctggca atggcacaga tgtcactgtc tttcctgttc
    21121 aggaaaatat ccatcggaac aatatcctgt caaaaaccat tgtcccagct cgcatttcag
    21181 aagcagttag cgctaaatcg caggctatgg cggtgaaaat agcagagcag cttaacctat
    21241 ctggcaccct ctgtgtagaa atgtttgtgg caggcgacga gattttggtc aatgaaatcg
    21301 ccccacgtcc ccacaactca ggacattact ccatcgaagc ctgtgatttc tcccagtttg
    21361 acacccacat tttaggtgta ttaggccagc cattaccagc tgtcaaactc catgccccag
    21421 ccattatgct caacgtcctc ggccagcaca tggaacaagc ccaacgctac gccacagaaa
    21481 accctagcgc ccacctccac ctctatggta aaatagaagc caagcacaac cgcaaaatgg
    21541 gacacgtgac ggtgtttaac agtcaatcag atgaggttga agaattttag gaggaattaa
    21601 tcctatgata aaaatcattg ttcacgcttt tattgaaaat ggtgaaacag gtgttgttga
    21661 agttgtcttt gcttcggaaa accaagaatc catttctgaa aaaatgacgg agctacaaaa
    21721 gcaatatcca aacgattacc ttgctatcta tgatttacca ctagatacag acctatcgca
    21781 attggcccac tatccgtcaa tagcgatagg caaaggggag tttgagtagt taaggaagat
    21841 tagtatttcg gattgagtgt tattgggaca atttatggct atgcctttca aaagattggt
    21901 catgatgttg agcatgttgt gagaattgag aatcgtaatc agatttcaga agttggtaaa
    21961 tgacttaatg gataattcta gatactgatc tcgagcaatc ataagagaaa tgttgaaatt
    22021 gtagcttctg gaggtgtaga actcaaaaat tatcgtggtg agatatttcc atataaaact
    22081 tctaagcgta tttcgtctag attgataaca tatagatagg tttgtacata atgaacttac
    22141 tagatgcatc atgacaaagc agatctttta tatacatgca aagaggttta caatattggt
    22201 atagtcaact attgatgccc taacttttaa tcacaatata gaaattattg cgaatagact
    22261 ttaaaagcat tactattaac tatgtagaaa ggaaatgagc gctagaattt tcaaactgaa
    22321 cctgagcgga aagctcggaa tttagataaa tttcctcgga cgtaaatgtc cgtctttagc
    22381 tttctaaaat tcagttgctt tctggctgtt cttggtatct taattatgct aaaccgttat
    22441 tcacgccctg agatggcgaa gatttggagt gaagagaaca agtaccgtgc ttggttggag
    22501 gtggaaatcc tcgctgatga ggcatgggct gagttgggtg agattcccaa ggaagatgtg
    22561 gcgaagattc gcgccaatgc gagttttgac atcaatcgta ttttggagat tgaagaagag
    22621 acccgtcacg atgtggtggc ctttactcgt gcggtgtctg aaacgctcgg tgaggagcgc
    22681 aagtgggtcc actatggctt gacatcgact gacgtggtgg atacggccta tggctatctc
    22741 tacaagcagg ctaatgacat tatccgtcgt gaccttgaaa actttaccaa cattgtggct
    22801 gagaaggcta aggagcacaa aatgactatc atgatggggc gtactcatgg tgtgcacgcg
    22861 gagccaacga ccttcggtct caaattggcg acctggtaca gtgaaatgaa gcgtaatcaa
    22921 gagcgttttg agcatgcggc tgctggtgtt gaggccggta aaatctcagg tgctgttgga
    22981 aactttgcca atatcccacc atttgttgag gagtatgtct gtggcaagct aggcattcgc
    23041 ccgcaggaaa tctcaactca ggtcttgcca cgagaccttc atgccgagta cttcgcagtg
    23101 cttgctagta tcgcgacatc aattgaacgc atggcaactg aaattcgagg cctgcaaaaa
    23161 tctgagcaac gtgaggtaga agagttcttt gccaaaggac aaaagggaag ctctgccatg
    23221 cctcataagc gtaacccgat cggctctgaa aacatgacgg ggcttgcgcg tgtcattcgt
    23281 gggcacatgg tgacagccta tgagaacgtg gcgctttggc atgagcgtga tatttcgcac
    23341 tcgtcagcag agcggattat cacaccagac acgactatcc tcatcaacta catgctcaac
    23401 cgttttggca atatcgtcaa aaatttgaca gtctttccag aaaacatgac tcgtaacatg
    23461 aactctacct ttggcttgat ttacagccaa cgtgtgatgc ttaagctgat cgaaaaaggc
    23521 atgacgcgtg aggaggcgta tgacttggta cagccaaaga cagcctattc atgggacaac
    23581 caagtggact tcaagccgat ccttgaggca gacgaaaata tcactgcaaa attaaggcaa
    23641 gatgagcttg atgagctctt caatccagct tattatacca agcgtgtcga tgctattttc
    23701 gaccgattag gattatagga agaaaacagc gcgtcttttt agactgtagc taagcccaga
    23761 tttgtttaaa aagtcttgaa aatgaattcc tcggagctaa ttctcaaaat gaagaatagt
    23821 atttcaagag aggctgtcac tagctatatc gcttaagaaa atgctctaaa atagacattt
    23881 tttcaatctg agaaggcaat aggccttctt tttttctaaa aatacagaaa tgttattata
    23941 gaatggagtc aaaaaattaa taattaatta aattatgtga tataatgaaa gaaatagtgt
    24001 cttgaagagg gaaacatgtt agacaatttt ggtgaaaagg tgagagacct tcggtatcag
    24061 aaaaaaatta ccagagagga tttatgtgga gatgagtcag aattatccat tcgtcaattg
    24121 gcacgaatag aactgggcca atcgattccc agcctatcaa aggtggtttt tattgctaag
    24181 gctttggacg ttagtgtcgg ctttttgaca gacggagagg atttggagct accgaagcgc
    24241 tataggagct taaatatttg attttaagaa caccgaccta tatggacgat gacaaattaa
    24301 agctgcgaga agagcaattt gacgaaattt ttgaagatta ttatgaccag ttgccagagg
    24361 aagaaaagct tgtggtggat tgcttgcagt ccataatgga tacgttatta accgagaata
    24421 tcaattttgg agttgggtta ttacaggaat actttgaaca aacaaaaagt aagactcaat
    24481 ttagagagaa tgatctcatt cttattgagc tgtatttagc gtacctcgac attgcaggaa
    24541 tgaatggaga gtattcagat aaaggattct atgattcttt gttagacatt ttgttaaatc
    24601 agtttgaaca ttttgaatta gaggaattat ttattgtcaa taaaatagct ataggaattt
    24661 cctcgttgag catcaaaaac aataagccgg agattcttga gaaggttatt gtacttagtc
    24721 aaaaaattat cctcaagact caggatttta atagaatgcc tatcttaaat ttgatagagt
    24781 ggaaatatgc tctaatgaag aaaaaagaca tagaaatggc caaaaaatgc tatgctaagg
    24841 catgcctgtt tgctcaatta acaggagatc agtatttgga aaagaaattg agagaagaat
    24901 ggggtaaaga tataaaacga tatcaatagg acaaaaatgt catttttatc aaaaatggaa
    24961 taatatataa tctttatata acaaataatt gattaaagga gttccattta tatgtttaaa
    25021 aaataccaat actatctgtt tttagctgct ttatttctac ttcattctgc ccaattactt
    25081 agtgatattg actggtggcg tgttggttaa agctaaatca tctatttatg ctataatagc
    25141 tctatgacaa gaattttaga taatgatctg ataggcgatg aaggatctgt tgagaggaca
    25201 ctacgtccac agtatttacg tgagtatatt ggtcaggata gggttaaaga ccagctgatg
    25261 atttttattg aggcagccaa gaggcgtgag gaatccttgg atcatgtcct gttatttggt
    25321 tccccaggct tgggtaaaac aacgatggcc tttgtcattg ccaatgaatt gggagttcat
    25381 ctcaagcaga cctctggccc agccattgaa aaagctggtg atttggtggc aattttgaat
    25441 gatttagagc caggagatgt cctctttatt gatgaaattc atcgtatgcc gatggctgtt
    25501 gaggaaatct tgtacagtgc catggaggat ttttacattg atatcatgat tggcgctgga
    25561 gacactagcc ggagtgtgca tttggagctg cctcccttta cattaattgg agcaacgact
    25621 cgtgcaggca tgctgtcaaa tcctttgagg gctcgttttg ggattactgg gcatatggaa
    25681 tattatcaga cagctgattt aacagagatt gtggagcgta cagctgatat ttttgacatg
    25741 acaatcaagc atgaggccgc ttatgaactg gcacgcagga gtcgtggaac ccctcgtatt
    25801 gctaatcggc tgttaaaaag ggtgcgtgat tatgctcaaa ttatgggtga tggaatgatt
    25861 acgactcaaa tcacagataa ggctctaacg atgttagatg tggatcaaga aggtttagat
    25921 tatgtggacc aaaagattct tcgtaccatg attgaggtgt accaaggagg gccggttggt
    25981 cttgggactc tatctgtcaa tatagcagag gagcgagata cagtagaaga catgtacgag
    26041 ccttatttaa ttcaaaaggg ttttatcatg cgtaccagaa caggccgagt tgtcaccgaa
    26101 aaagcctatc agcacttagg ctatccctat gaaaaaacca ttaagacata aatagctatg
    26161 taagacttga ttcctttgtt tttaccggtg tcaagtcttt tgtattgtca atagcttact
    26221 gagtaaaaaa gtaaaacgat gtgaggtgag gggtgattgg tcagggaagc agaggtgctt
    26281 tcactagaca aagcattaaa aaacattttt agatcaattg aacgaaaatt ataagagcga
    26341 tttctccttt tggccctata attttgctat aataggtaaa aggagttttt catgaaaaaa
    26401 gtatgctttg tttgtcttgg aaatatttgt cgtagtccta tggccgaatt tgtcatgaaa
    26461 agtatggcca gtcctgatga gctacaggtg gagagtcgtg caacctctgg ctgggagcat
    26521 ggcaatccaa ttcatcatgg gacacaatcg ctattacagc aatatcagat tagctatgat
    26581 accaagaaaa cctctcagca aatcaccagc tttgactttg aagcctttga ctatattatc
    26641 ggaatggata gccataatat cagagatttg aagcaaatgt ccaagcatca gtgggattcc
    26701 aagatccatc tttttattga aggaggcgtt ccggatcctt ggtatacagg agattttgaa
    26761 gaaacctacc gcttggttaa agcgggctgt cagcattggt tgagtcaaat cagcgctgaa
    26821 catgaatcac atgtggaaat agatgagtaa tagtaatgaa agcaataata aataacattc
    26881 aaaaatggca gatcactcgg acaaagctag agattatttc agtccttgtg attattgtct
    26941 gtggattgtc ggtttttacc ttgaccatat cctcaaaagc aagcttgacc tatgacaatg
    27001 ggcaaatcaa gtacaccggc tatgtcctta atcatagaat gaatggtaaa gggaaattgg
    27061 tttaccctaa tggcgatacc tatgttgggg attttaataa aggtgtcttt gatggagaag
    27121 gaacgtttac agctagtaca gggtggtctt acagcggaca atttaaaaaa ggtcaggctg
    27181 atggcaaggg tactttgaag gcgaaggatt caaaggttta caaaggaacc tttaagcagg
    27241 ggatatttca aaaatgagga taaaatggtt ttcgtttatt agggtaacag gtcttttgct
    27301 ggtgttgctc tatcactttt ttaagcatac tttttcagga ggctttgttg gcgttgacat
    27361 cttctttact ttttcaggct atttgattac agccttgttg attgatgaat atgtctcaaa
    27421 acaaaccatt gatgtggttg ctttttttag aaggcgtttt tatcgtattg taccgccgct
    27481 tgtcttgtta attctcttga caattccctt tactttttta gtcaaaagtg acttcattgc
    27541 tggtatcggt cagcaaatag cagctgccct agggtttaca acaaatagtt atgagctact
    27601 gacaggcagt agctatgaaa gtcaattcat tccgcatctg tttgtgcata cctggagctt
    27661 ggccattgag gtgcattttt atttgctttg ggggctgttg gtttggttat tagctaaaaa
    27721 aggctacagt cagaagaaat ttagaggcat tctgttttta atttcttccg cagtgttcac
    27781 gcttagctac ttcagcatgt ttatcagagc cttctttgta tcagattttt cttctgttta
    27841 cttttcaacg ctttcacaca gctttccttt ctttttagga gcgatgtttg caaccatgac
    27901 gggaattaag gacacgactg ttcgctttca aaagaatgtt aagctgtggc caaggctaca
    27961 tgttattgga gtgatggctg gcgcttttgc tctgttgttg tttctaacgc ttgtgttaga
    28021 ttttaaccat atctttacct atcttttcgg ttttgtctta gccagtcttt ttgcttcggt
    28081 aatgatttat gctgcgcgtg ttttgagcga tcaaacacca acctggcagg aaccactgct
    28141 tgtgacctat cttgcggata ttagctatgg gatttattta ttccattggc cattttacat
    28201 tatttttaca cagctgatgt ctaactggct ggcagtgatc ttaacggttt tcttttcagt
    28261 agtgttttca acgctttctt attacattat tgagcctttg attcaaggca agacaccaca
    28321 gctttttggt ttagcaattg attgtaatcc ctataagaaa tggttatcag ggcttgcttt
    28381 aggactcttt ttgttgatgg ttggtacctg tttgacagca ccaagggtcg gtaattttga
    28441 gacccagctt ttagtagatt ccttgcagca atctcaaagt aatctcaata agacacatac
    28501 tttggcagca ggagatgcgc atgctcttag tgatgttagc attattggtg actcagttgc
    28561 cttgaggtct agtgacgctt tttcaaaatt aatgccgact gctcaactag acgctgctgt
    28621 cagccgcaat ttcagtgaag cctttgagct ttttgaaaat catatccaat ccaagagctt
    28681 atcaaaaaca acggttttag ctgttggtgt taattctctt tataattatg cgcaggatat
    28741 tcaaggcttt atttatgcac taccaaaggg gcatcgcttg gtgattgtgt cgccctatga
    28801 tgctaagaat gcagcacagg tagcagaggc tagagagcat ttgttgcagc tagctaaaaa
    28861 atatagctat gtaacagttg ctgactggta caaggcggca gtcgaaaatc ccaatatctg
    28921 gtatggtagt gatggggtcc actacaataa cgacgccaaa ttaaaaggtg ctgacttata
    28981 tgtctcaacg attcaggcgg ctgttgagcg agcagcaaaa aaagatgcta aatagtggtg
    29041 ctaacaacaa tttgttaaga attaataacg aaggcttggt cttacaaaca gatcaagcct
    29101 tttcatgatg tgatttttag atcgtcttgc gccctttagc gcgagataaa gctccacctg
    29161 ttagacagtg tcattattgg ctgttattgc tgacggtgac gtgcttttaa aaacggatca
    29221 ttaaataatt tagcctgatc taaaaaagaa agcgctttcg gaacaaagtg aatgcgtcag
    29281 ccattatttc agaaaaaatc caccaagcca aaccccttgt tatcaaagag tttcggaaat
    29341 tgattgaaaa aacatcacaa ttttattgtg aaatgattta caaaatgcca aaaaatgata
    29401 taatattttt gtaaacaaaa ttgtgaaact tttaacaagg taaaggagtc tcaaatgact
    29461 gaaaaaaata gtactgttga aacaacatct gttgccgcaa caattgacgc tcttgttcaa
    29521 aaaggtttag tagcgcttga taaaatgcgt cagttaactc aagaacaggt tgactacatt
    29581 gtagcgaagg cctctgttgc tgctttggac gcacatggtg agttagctaa gcatgcctat
    29641 gaagaaactg gtcgcggagt ttttgaagat aaggctacca aaaacctttt cgcatgtgag
    29701 cacgttgtta ataacatgcg tcaccaaaaa acagtaggta tcattgaaga agacgatgta
    29761 acaggtttga ccttaattgc tgagccagta ggtgttattt gtgggattac cccaacaact
    29821 aacccaacgt caacagctat ttttaaatct ttaatctcct taaaaacacg taaccctatt
    29881 atttttgcct tccacccatc agctcaagaa tcatcagctc atgcagcacg cattgttcgt
    29941 gatgcagcca ttgcagcagg agctcctgag gactgtgttc aatggattga aaccccatca
    30001 ctagaagcaa ctaacgctct gatgaatcat gatggtattg caacaatcct tgcaactggt
    30061 ggtaatgcta tggttaaggc agcctactca tgtggtaagc cagctcttgg ggttggtgct
    30121 ggtaacgtgc ctgcctatgt tgaaaaatcc gctaacattc gtcaggcagc acacgatatt
    30181 gtcatgtcta aatcatttga caatggtatg gtttgtgctt ctgagcaggc tgttattatc
    30241 gacaaggaga tttatgacga gtttgttagt gaatttaagt cttaccacac ttactttgtc
    30301 aacaaaaagg aaaaggctct gttagaggaa ttctgctttg gtgctaaggc taacagtaaa
    30361 aactgtgcag gtgctaagct gaaccctaat attgttggta agccagcagc ttggattgct
    30421 gagcaggcag gctttacagt accagaagga acgaatatcc ttgcagcaga atgtaaggaa
    30481 gtttctgaaa atgagccatt aacacgtgaa aaattgtcac cagttatcgc tgttttgaag
    30541 gctgaatctc gcacagatgg tgttgaaaag gctcgtcaaa tggttgaatt taacggactt
    30601 ggtcactcag ccgctattca tactgctgat gcagacttag ctaaggaatt tggaacaaaa
    30661 attcgtgcta ttcgtgtgat ttggaattca ccttctacat ttggtggtat cggtgatgtt
    30721 tataatgcct tcctaccgtc attaacattg ggctgtggtt cttatggacg taactcagtt
    30781 ggtgataatg ttagtgctgt aaatctcttg aacatcaaaa aagtaggaag acgtagaaat
    30841 aatatgcaat ggtttaaagt tccttcaaaa acatacttcg agcgtgattc aattcaatac
    30901 cttcaaaaat gtcgtgacgt tgagcgtgtg atgattgtta ccgaccacgc tatggttgag
    30961 cttggcttct tagatcgtat catcgagcag cttgaccttc gtcgtaataa ggttgtttat
    31021 caaatttttg cagatgttga gccagatcct gatatcacaa cggttatgaa aggtactgag
    31081 ctgatgcgta cctttaagcc agatgcgatt atcgctcttg gcggtggttc tccaatggac
    31141 gctgcaaagg taatgtggtt attctatgag caaccagagg ttgacttcca tgatcttgtt
    31201 caaaaattca tggatattcg taaacgtgcc ttcaagttcc ctgagcttgg taagaaaaca
    31261 aaatttgtgg ctattccaac aacctcaggt acaggatcag aggttacacc gtttgctgtt
    31321 atctcagata aggccaacaa ccgcaagtac ccaattgctg actattcatt gacaccaacg
    31381 gtagccattg ttgacccggc gttggtgctt acagtaccag gcttcattgc agctgataca
    31441 ggtatggacg tgttgaccca cgcaaccgag gcttacgtat cacaaatggc taatgacttt
    31501 acagatggtt tggcccttca agccattaag attgtctttg aaaaccttga aaaatctgtt
    31561 aaggaagctg actttgagtc acgtgaaaaa atgcataatg cctcaacaat ggcaggtatg
    31621 gcctttgcta atgccttcct gggtatttct cactcaatgg ctcataagat tggtgcacaa
    31681 ttccatactg ttcatggacg taccaatgct atcttgcttc catacgttat tcgttacaat
    31741 ggtacccgtc ctgctaaaac agcaacatgg cctaagtaca attactatcg cgccgatgaa
    31801 aaatatcaag acattgctaa gttgctagga cttccggcat ctactccaga agaaggtgtt
    31861 gaatcttatg ctaaagctgt ttatgatctt ggctgtcgct taggcattaa gatgaatttc
    31921 agagatcaag gaattgatga ggaagaatgg aaggcacaca ctcgtgagct tgcttatctt
    31981 gcctacgagg atcaatgctc acctgctaac ccacgcttgc caatggttga gcacatggaa
    32041 gaaatcatga atgatgctta ttatggttac gcagagcgtc caggacgtcg gaaataatat
    32101 caatcattaa tagtaaaaat aggagctgct tggcttctat ttttttatct agctatgaaa
    32161 agggctgtgt tagatgaaaa agtcggcagt gccttgtgtt gagatagctt aactcagggg
    32221 tagtttctca gatatcatat aaagctttta agacaatggt tttacagagc attccatcag
    32281 agggggaagc ttcatttgcc atattcataa agtggctgat agttacgact tagctgcact
    32341 tagcaattag ctgaagaaaa taacatgttg cgtctatctg atgagcttta ttttctaata
    32401 aaacaaggag tgattgcttt tttaatgatg ttaatagcgt taaaaacctt tatatatcaa
    32461 acaaaaacca aaataatggt attgtcagac tttttctaaa attacccttt attaattgac
    32521 aaagagggtg taaaaaatta tactaaaaat gtaatcgatt acattttcta gactaaattt
    32581 ggagacgttt tatgaaagca gctacatatg ttgctccagg tcagctggag cttattgatc
    32641 aaccaaaacc agagattctt gctccgacag atgctgtggt tcgtttattg aaaacaacaa
    32701 tctgtggaac agacttacat attttaggtg gagatgtccc agagactact catggtacca
    32761 ttttaggtca tgaaggtatt ggtattgtcg agtcagtcgg ctctgcagtg aacaacttta
    32821 aggtaggtga taaggttatt atttcctgta tcacagcctg taatacctgc tattattgta
    32881 aaaaaggaat tcctgctcat tgtgaaagcg gtggctggat tctagggcat ttgattaatg
    32941 ggacacaagc agagtatgtt catattcctc aagcagatgg cagtctttat catgctccta
    33001 aaaccgttga ggatgatgcc ttggttatgc tgtcagacat tttcccaact tcctatgaaa
    33061 taggcgttca gtctgcaaag gtaaagccgg gtgatacagt gtgtatcgtt ggagcaggtc
    33121 ctatcggact agcagctctt ttaacagcac aattttattc accagctaag ctgatcatgg
    33181 ttgacttgtc agaatcacgt ttagaagcag ctaagcgctt tggagcaaca gatacgattt
    33241 gctctggtga ccttgatgat attgtcaaaa aagtccatga attaactgat ggtcgaggtg
    33301 ttgatgttgc cattgagtgt gtaggctatc ctgctacctt tgatatttgc caaaagatta
    33361 ttgctattgg cgggcatgtt tctaacgttg gtgtccatgg aaaaccagtt agtttggacc
    33421 tacaggacct atggatcaaa aacattacaa tgtcaactgg cctagtaaac gctaatacaa
    33481 cagaaatgct attgaatgtg ttgaaatctg gtaagattga tgcaactaag atggtaacac
    33541 atcactttaa gctgtcagag gttgaaaaag cctatgaggt ctttaaaaat gccggcagta
    33601 ataacgccct taaagtgatt attgaaaatg acattacagc ctaaaggaat aaggtataaa
    33661 tagataaaag tgacaacagc atttggaatg gtctagatgc tgttttttag ccaacttaac
    33721 tggttaagtt tattttcaga aaactttcaa gaaattggtt gacaaacctt gtgaaaaagt
    33781 atacaataca aattgtaaac ggttgcaaaa atagataaac cgagacttag aaattggagg
    33841 catcctatga aggctgtagt tgttaaccaa accagcagtg gtgtagaggt tgtagagcat
    33901 gatgtaccat caatcggtca tggagaagct cttgttaaag tagaatattg tggcgtatgt
    33961 catactgact tgcatgttgc gcatggtgat tttggtcagg ttccagggcg tatcctcggt
    34021 catgaaggta tcggtattgt cgaaaagcta ggtgaaggcg ttacctcctt aaaggttggt
    34081 gatcgtgtat caattgcttg gttctttgaa ggctgcggtc attgtgaata ttgtacaaca
    34141 ggtcgcgaga ctctatgccg ttcagtcaaa aatgctggct attcagttga tggtgggatg
    34201 agtgagtatg cagttgttac agctgactat gctgtgaaag tgccagatgg tcttgaccca
    34261 gctcaagcat catcaattac ctgtgcaggc gttacaacct ataaggctat caaagaagca
    34321 ggtgccgctc caggacaatg gattgttatc tttggtgccg gtggacttgg taacctagct
    34381 gttcagtatg ctaaaaaggt tttcaatgct catgtcgtag cagtggacat taacaatgat
    34441 aagctagagc tggccaagga ggttggagca gatatcgttg tcaatggtaa agaaatcgaa
    34501 gatgttgccg gctatatcca agaaaaaaca ggtggtgctc atggcgttgt ggtaaccgct
    34561 gtttctaaag tagcctttaa ccaagctatt gatagtgtgc gtgcaggagg aactgttgtt
    34621 gctgtaggac ttccatcaga atacatggaa ttatctatcg taaagactgt cctagacgga
    34681 atcaaggtag tcggatcact tgtgggaact cgtaaagact tggaagaagc ctttgccttt
    34741 ggtgcagaag gtctggttgt gccagttgta gaaaaggttc cagttgagac tgctccagaa
    34801 gtctttgacg aaatggaacg tggtctcatt caaggaagaa aggtattgga tttcacgctt
    34861 taaggctgat ttcagaaaaa gtcagcagcc agacaagctg attgtcccaa atgatgaata
    34921 aagtccttag aattaatttt ctaagggctt ttttggtgaa actaactggt aaaaaaagct
    34981 tggtatctaa agatgtaaaa gagccagcta gttattaata ccatgattgc cccttgaaag
    35041 acagtaccag agaaagttgg acatattgta acctctgata gagatactgg gtttgaacaa
    35101 tattagagat taacacagga actcaatcta gaagtttatt tctctgctcc tcacacccct
    35161 tgataacgta ggacaaatga aaataccaat gggttaatca aagagtagtt tcctaaagga
    35221 actgacttga ctgatattga gagctctatc atataagagt gggaagataa atgaaatgat
    35281 cgttctagaa gatgtcctaa ctggaaacta ccttataaac tcttttatgg aaaagcgttg
    35341 cacttaattt gacaattcgt cttcacaaat tttaggaagc actgtaggaa aaaagaataa
    35401 tgacataaca tattgctaaa aacatgggtt ataagctaaa ttattatcta cgtttttagt
    35461 aacaaggtag tatgatttaa aatatagatg aaaaatgttg tgtcccgaat aagggaagtt
    35521 ttttaggat
//
LOCUS       DARYMD010000021        33456 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYMD010000021 DARYMD010000000
VERSION     DARYMD010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33456
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(310..909)
                     /locus_tag="TU818_000932"
     CDS             complement(310..909)
                     /locus_tag="TU818_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL0923761.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSLWTLASAKDHLKPHA
                     NSSTMLFVSKISHSAQAVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYLIDASFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
     gene            complement(1487..3433)
                     /locus_tag="TU818_000933"
     CDS             complement(1487..3433)
                     /locus_tag="TU818_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL0923762.1"
                     /translation="MKIQDLLRKDIMILDLQAVSKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGAAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIIMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TU818_000934"
     CDS             complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TU818_000934"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL0923763.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESINTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDALAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEATYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            complement(4338..5051)
                     /locus_tag="TU818_000935"
     CDS             complement(4338..5051)
                     /locus_tag="TU818_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL0923764.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKEIIAQKAAELVFDNDVIFIDAGTTTEFLLPFLQ
                     LKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIRQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            complement(5486..6409)
                     /locus_tag="TU818_000936"
     CDS             complement(5486..6409)
                     /locus_tag="TU818_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL0923765.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQAIKENGL
                     KISGDVEETVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTAGLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKENILKIK"
     gene            complement(6421..7479)
                     /locus_tag="TU818_000937"
     CDS             complement(6421..7479)
                     /locus_tag="TU818_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL0923766.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKYPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            complement(7611..8603)
                     /locus_tag="TU818_000938"
     CDS             complement(7611..8603)
                     /locus_tag="TU818_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL0923767.1"
                     /translation="MQEKIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     AVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKADGNFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFAGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKNSHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEEITLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHSTALID"
     gene            complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TU818_000939"
     CDS             complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TU818_000939"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL0923768.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSGLSEGEN"
     gene            complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TU818_000940"
     CDS             complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TU818_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL0923769.1"
                     /translation="MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRV
                     DVEIMEGLDDED"
     gene            complement(11117..11356)
                     /locus_tag="TU818_000941"
     CDS             complement(11117..11356)
                     /locus_tag="TU818_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL0923770.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TU818_000942"
     CDS             complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TU818_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL0923771.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(12069..12686)
                     /locus_tag="TU818_000943"
     CDS             complement(12069..12686)
                     /locus_tag="TU818_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL0923772.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILFSVMLVVYLIRQLDIINNPK
                     ALAHLIKDHLLIGAICFFILQIVQVVVPIIPGGVTTVVGFLAFGPILGFMLNVFGICI
                     GSSILFQLVRRYGKPFILLFLSMEQLQFYEKKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(12679..13902)
                     /locus_tag="TU818_000944"
     CDS             complement(12679..13902)
                     /locus_tag="TU818_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923773.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(13914..14624)
                     /locus_tag="TU818_000945"
     CDS             complement(13914..14624)
                     /locus_tag="TU818_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923774.1"
                     /translation="MPDEKKELIQLKSIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(14624..15886)
                     /locus_tag="TU818_000946"
     CDS             complement(14624..15886)
                     /locus_tag="TU818_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL0923775.1"
                     /translation="MSKRGKIKLSTKTKGIIAGAVALTVVVIGGVLWKQQQDTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSTAGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TU818_000947"
     CDS             complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TU818_000947"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL0923776.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     SKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFAN
                     AIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQP
                     PGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEH
                     PVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQ
                     GVPLFTALDTAVAMLRVLESRTFSIEAI"
     gene            complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TU818_000948"
     CDS             complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TU818_000948"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL0923777.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGVQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(20909..21844)
                     /locus_tag="TU818_000949"
     CDS             complement(20909..21844)
                     /locus_tag="TU818_000949"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL0923778.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(21902..23161)
                     /locus_tag="TU818_000950"
     CDS             complement(21902..23161)
                     /locus_tag="TU818_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL0923779.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYLFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TU818_000951"
     CDS             complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TU818_000951"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL0923780.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPG"
     gene            24060..24674
                     /locus_tag="TU818_000952"
     CDS             24060..24674
                     /locus_tag="TU818_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL0923781.1"
                     /translation="MNDITRKINHKQLIQITTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFILPGFPDDFLCM
                     VAGLSSMSIKTFTSIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(24755..25645)
                     /locus_tag="TU818_000953"
     CDS             complement(24755..25645)
                     /locus_tag="TU818_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL0923782.1"
                     /translation="MEIKITESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGLPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHIKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSEKDRKKQTVTAKGKEALTLFKVLERFGHYTFV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGKGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(25635..26093)
                     /locus_tag="TU818_000954"
     CDS             complement(25635..26093)
                     /locus_tag="TU818_000954"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL0923783.1"
                     /translation="MKRISFIMAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITVLVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRLRLSYVVDMIHLDVINFAIFNVADSYLTIGVLLLVICLWKEEDYGN"
     gene            complement(26321..27250)
                     /locus_tag="TU818_000955"
     CDS             complement(26321..27250)
                     /locus_tag="TU818_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL0923784.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTAGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSIASQHYDFL
                     PALITAFSQKHAGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKNHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKEKQAIDNGT"
     gene            complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TU818_000956"
     CDS             complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TU818_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL0923785.1"
                     /translation="MIKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(27972..28304)
                     /locus_tag="TU818_000957"
     CDS             complement(27972..28304)
                     /locus_tag="TU818_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL0923786.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSVEQMTGLEPALEMVDGGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHLSE
                     YVQKPVMN"
     gene            complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TU818_000958"
     CDS             complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TU818_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL0923787.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(28665..28739)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(28861..30054)
                     /locus_tag="TU818_000959"
     CDS             complement(28861..30054)
                     /locus_tag="TU818_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL0923788.1"
                     /translation="MLKDFQYKKTMLSVLTLIVVILVFGLAFDLLGMSKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEEKI
                     QKDILRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            30319..30936
                     /locus_tag="TU818_000960"
     CDS             30319..30936
                     /locus_tag="TU818_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL0923789.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELITIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLTLSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(31234..32463)
                     /locus_tag="TU818_000961"
     CDS             complement(31234..32463)
                     /locus_tag="TU818_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0923790.1"
                     /translation="MRGLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTKRKTRNLIVIGFIQSLLFTLVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFAQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEAGVSLMKQFKVMYTR
                     MTETFKKIDHISFVMLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSLVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLVQTQGIAFLLVGVSNALQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALALSTSSTRG"
     gene            complement(32498..>33456)
                     /locus_tag="TU818_000962"
     CDS             complement(32498..>33456)
                     /locus_tag="TU818_000962"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL0923791.1"
                     /translation="DDNIIFVDLESSYLYNTNSLIGIYSEISLKEWNDVDGKVADCYK
                     IGNLFLYLLGKLHIRDNNILTGELKNLLLQKGINSNIYKLIEYLLSENSDIEEAINMI
                     RNDIYSYHFQCTYKLNTNIAISDDWNQELVNIISLQDTLITKYNKILDKSDEVLMQLK
                     SEVNLGLNGLAGVLFYLSSISYDNEIIEKGIDFILESLVEDSDGNRGVLISENSVSPY
                     LSNGTAGIVQLLIYVNSDKYIKDIKNLSESLLVEFAQFSGLWNGMLGIAMTLLQVFRL
                     TNDTLYLEKACELLISSKIMSEHHIKLQYEFRYAVSIFNQVK"
BASE COUNT        10131 a         7728 c         5923 g         9674 t
ORIGIN      
        1 aatcaaaaga agatagcatt tctgctatct cactgttagc cactacttac aggtaaaaat
       61 acaccttgtc tatttgtagt ttaactatcc atttaatcca tcaataagcc aaaccagacc
      121 gtttaatcat ctacccagcc ttacacatag tattttctca catcatttgt agaattgctt
      181 tctccttgca tgtcaccatc tcgtcttaaa cgttcgtaaa gggctgtttg atcttttcta
      241 actattttag aaaattattt tgctgttctg atgaggttaa tctcgttaga tcagtcatgc
      301 tggaggtagc taccgtatgg gagcgtcaaa ataagtcagc tgataatccc ctataatacg
      361 attgagcttt tcgccatagc tagtatctgt ggcatatgtg cctgttaaac tagcggtggc
      421 ctgctgataa cttgtatgaa tacctcggtg agtagggcga taaagcgggt cactcaaaac
      481 cctagcataa tcctcaaagc aggctgttaa gctgccatag gaccgaaaag aagcgtcaat
      541 tagataaagg ttgccttggc catcatcttc caaggtaggt aaaataactg attttccttt
      601 atagcttcct ttgataccaa aaaaattata atagggctct tgacttagct tagattgacc
      661 atttgctgac tccaaaatag cctgtgccat catgactgag gcatagagct tgtttcgctg
      721 cgcaactgcc tgagcggaat gactaatctt gctcacaaat agcatggttg agctattggc
      781 atgaggctta aggtgatcct tagctgacgc taaggtccaa aggctaagca acatgctgcc
      841 taaaacaata ccagcagcca gccaagagct agcttccctg tggcttcttc tagctttcct
      901 cctcttcaac agaaatatcc tcacttcctt gcttttaaac ctagtatagc aaaaattaaa
      961 agcaaaatgt agccagacca catgctcacc tcaaaaacag gccttatgac ttctaaaaag
     1021 acctagcagc cacaacaggc gcataaaaag tttttaacaa gaaaagaaga ctttgctgta
     1081 tttcaatcca cgctcctgca aagggagcga tacaaaaaat aaatggaata tctacaatca
     1141 aatgatttca atgtttagct atttcaagaa tatatcttat ttttgataga tgttactata
     1201 ggaaaaacgt tgatagtatc tactttaatt gatactataa ttcgaaaata actgtttcgc
     1261 acgtttggtg tggcttagtt tagcagggct attgggtcac tgcttagcta ttctagatca
     1321 gattgattct ctctaaatat tagcttttcg ccagtcatca ctactagcaa caaacaaaac
     1381 gcacgacatc atgtaaaaac aggctgatgt catgcgtctg atgttttatt aagactaggt
     1441 ctaattcaga agctttccct agtacttgtg gctttatagc cagtaactaa gcttttttac
     1501 gaagtgcgcc aaagagaata ccagaaacca ctgctccaat agcgacaaac aataggtata
     1561 agaaaggatt gcttgtcaaa gcgataacga agataccgcc atgtggtgcg attaatttga
     1621 cacctgctag accaacaaga gcacctgtta gggcagagcc agcgataaag cttgggatag
     1681 cgcgtgctgg gtctgctgca ccaaacggaa tggctccttc tgtaatgaag gaaagtccca
     1741 taataatgtt ggtcaagcca gattcacgct cttccttggt aaatttgtct ttaaataaga
     1801 gtgttgccac aaaaacagct agaggaggca ccataccacc tgccatgaca gcagccataa
     1861 caactgaccc accgcttgca acggttgcag caagtgttcc tgtaccaaag acataggctg
     1921 ccttattcac tggaccaccc atatcaacag ccatcatgcc gccaacaaga agtcccataa
     1981 gaactgcaga gctacctgac agactttcta agaagtggtt caatgctgta ttgatagctg
     2041 ccataggaat attgatcagc agcatcaaaa gacctgtcac aagaacacca agtaatgggt
     2101 aaagaaggat tgacttgacc ccttcaagcg aacgcggaag ccctgcaagc acttgacgaa
     2161 gagcaagaat tactccccct gcaaggaagc cacctacaag cgcaccaaga aatccagacg
     2221 gtactcccgc taatgatagg ctagcctcac cgccagcagc aaatggaacc tttccaaaag
     2281 caagaccgct agaagcaatg gcacctgcca caaagcctgc cacaagacct ggcttttcag
     2341 cgatagaata agcaatgtag cctgctagca ctggcaacat gaatgaaaag gccgcaccac
     2401 caatatgttt aaagatagct gctatttcat ggtaggatcc caaattagac agctgatcct
     2461 ttggtacccc aagcatgttg tcaagcaaga aggcaagagc aattaggatt ccaccaccaa
     2521 ttacaaatgg cagcatttgt gatacaccac tcatcaggtg cttgtagaag gctccgccta
     2581 ggcttgtctt ttgagctgct tttgcttgtt cagcagcgcc attcttggca tgataaacac
     2641 taccagcatt gtttaaaatc agtgaaatca attcctcgct tttcttaata ccatctgcta
     2701 caggacgagc aatcaattgc ttaccatcaa agcgatccat ctcaaccgcc ttatcagcag
     2761 cgataatcac tcccttggcc tgcttgatgt catcagctgt caggcgattg ccaacccctg
     2821 aagcaccgtt ggtttcaacc ttgatgccga cacccatctg tgcagcctgc tttttcaagg
     2881 cctcttctgc catataagta tgtgcaatac ctgtcgtaca agctgtcaca gcaacgataa
     2941 actcctgagc atttgtagga acaaaagcta cctctttctg atcagaagcc gcatcaaaga
     3001 cagcaatcac ttcgtctgga cttgttgcct ttcgcagttg atctgcaaag ccatccttta
     3061 ataggtattg ggataattcg gctaaggccg ctaagtgagt atcatttgcc ccttgaggtg
     3121 ctgcaatcat aaagaacaga tcagttggct gaccgtctaa ggatttgtaa tcaacgccct
     3181 tgttagattt tgcaaagagc actgctggct ggtcaacaac aacatttttt gaatgcggca
     3241 tagcaatgcc atcgccaaga cctgttgagg tttgctcctc gcgagctaag atactctttt
     3301 taaacacatc aaagtcatgt acaatcccat gctctactag ttctgtaatc atttcatcaa
     3361 ttgcagcctc ttttgaaaca gcctgcaaat caagaatcat gatgtctttt cttaataaat
     3421 cctgtatttt catcgaacct ctacctcaac ctcattatat gtttttttaa tatcatcaat
     3481 tgctgctaaa tcatctgaaa aagcagttgc tgttccgcag gccactcccc attttagagc
     3541 ctctagcgga ctatgacttt tgacaaaggc acctgtaaag cctgccacca tcgaatcacc
     3601 agctccaaca gaattcttca cctgcccttt aataggctta gcaaaataag ttgcttcctg
     3661 agtgaccagc aaggcaccat caccagccat cgaaacgata acatgctgcg ctcccatgtc
     3721 aaggacctta cgagcatatg tttcaacgtc atctagccca tttaagctga cgttaaaaat
     3781 agcttctagc tcatggttat taggctttac gagcaatggg tgatacgcca atgcatctag
     3841 caaggtctgt ccttcaaaat cacagaccac ctgtgcccca gcttgtctga ccaatgggat
     3901 caagtcctta tagacatcat tgcctagact tgaaggcgct gagcctgcaa aaacaacaat
     3961 gtcctctgct gacacatttg ccaatatagc ctttaaatga tccaattgct gctttgaaat
     4021 cactggtcca aggccattaa tctctgtctc ctctgctgat ttgatcttaa cattgatccg
     4081 cgtatcctga tcaaccgtta caaagtcagt attgatgctc tcagcagcta gactttcctt
     4141 aataaaacgc ccagtgaagc cgcctaaaaa gccagtcgct gtattatcaa tgcctaatcg
     4201 ctgtagaatg cgactaacat taatcccctt tcctcctgca aatgtatcgt cactgaccat
     4261 gcggttaacc gctccaatat ctaattggtc tattctgaca ataaagtcta tagaaggatt
     4321 taaggttact gtgtaaatca tagtgcaatt accttcgctt tttccttgat tttcttcagc
     4381 attactgtcg aagatttctc tgtaatgatt tcaaccctat caattggagc aaccttgaca
     4441 aaggaaacat gaccaagctt tgttgcatca gctaatacat aggtgatttt agcattggca
     4501 atgacagctt ttttaataac agcctcctcc atatccggag tggttaaaaa tgcctcatcg
     4561 ataccattga taccaagaaa agccttatca aaattcattt gcctaatttg ctccaaggca
     4621 acatgaccga tgcttgcgtc tgttgtctgc ttgacatagc caccaataat aatggtcttg
     4681 atcgccatat caaccagtct agtcgcatga tgaatagaat tagtcactac tgttactttt
     4741 tttaattgca aaaaaggaag gagaaattcg gttgttgtcc cagcatcaat aaagatgaca
     4801 tcattatcaa aaaccagctc tgctgccttt tgagcgatga tttcttttat ttgactgttt
     4861 ttgacagatt tttcctgatt agataattcc tcttgtaagg aatgaaaaag ctcggcacct
     4921 ccatgcactc gatgaagctt gccctcacgc tccagctcat ctaaatctct acgaacagtt
     4981 gattctgacg agcttaacag ctgcattaaa tcctctagcg caacgtaatt ctcagctgtg
     5041 atttttgcca taatgagctg ttttcgtttt gattttaaga taaaaccacc cctttgtctg
     5101 aaatcgttta cagctctatt atactacact ttattccaaa gtcaagcact atctttcaaa
     5161 aacattcaaa ttcaatctta gacctctatt gccttaacaa taactgccaa ttgatcagtc
     5221 attgtccccg tcaatacctg tagactaatg attaacgact tttttattaa ctagagccca
     5281 aaaagcgctc acctgttgca aaagtctgaa acacaatagt ctcttacaaa tcaaaaagca
     5341 acggatttac tgtcgttgct tcataatgag agtctaggac aaagtctttt cagccaacaa
     5401 gacaaaacga gagagtcacc tattgtgagc ctctcgtttt attgtactga gaaattgttt
     5461 tatcccagac tccttatgtc taaacctatt tgatcttcaa aatattctct ttggcatgga
     5521 ctagctgtgt aatcaagcgg caataagggg tatcgatacc aagcttttca cccttggtat
     5581 ttaccgcacc gttgataaag tcaatttcag tcaagcggtg attttgaaca agatcctgat
     5641 gcattgatgg gtagtgatga gcagccttca ctgaggtttc catcacatag gctgtgattt
     5701 cctcttcatt aagctccacc ccctcagcac gaccaacaat aacaaactca tgaatgattt
     5761 ctttaaccat gtttaaacca tcttcgctgg caaataactc accaatcgtg caatcaagta
     5821 gggcacaggt tgagttcatt gtaccattga cacaggcttt tctccaaata tttggaacaa
     5881 cattatcatc ataagttgca ttcaattgag cgtcatttag caagtcagca atctgatgtc
     5941 ctgcctcttg gtttgctgga tccatgcttt gtagattaag cgcaccaact ccttgtaagt
     6001 gtacctgacc aggtccctca agacccgctg tccaaacggt aacacccatt aaaatattat
     6061 gctctggaat atagtgacga atcacatctt cgtgtccaag accatttaat aggcaaagta
     6121 ccttggtttc agggccaata atacctttaa tatcagtcag catttgtggc agctgcatgg
     6181 ctttggtaaa caaaatgata aggtcagctt ccttagtagc ctctgtcggc ttcatgatag
     6241 gaagctttac ggtttcctct acatcgcctg aaatcttcaa gccattctct ttgatcgctt
     6301 gaagatgtgc ttcccaatta tccagtaaaa taacgtcatt gtttgttttt gaaatttggt
     6361 aaccaaatcg acagcccata gctcctgagc ctgcaatata aactaacatg ctttttcctc
     6421 ttatccttca aatacaaaaa tatcttcttt ataaagcttt aaaatatcct tacaaagctt
     6481 atgtgccaca aaagcaactc caaatggaat gaccaaccaa gcaatgataa tgatcacaat
     6541 attgctgcca ccggcaagtg aagcaatagg accaactgca ccaacaagac caaagccaga
     6601 tgaggctggt gttccaatca gattaaacat tggaacggtt aaagagctaa caatagctgt
     6661 catcatcatt ggaatagcca taactgggta ttttaagaag tttggcatca tcattttcat
     6721 agcgccaagg gcaatggcaa ttggaacacc tgatttgtta acctttaacg ttgcccacac
     6781 aagaacagcg gttgttgaag caatacccat tgaggccgca ccagctgcca taccatttaa
     6841 gccgatagct aaaccaatcg caaccgttga gatcggactc acaatcaaaa gagcaaaggc
     6901 aatggcaatc aaaatagaca tcagaattgg ctgaagcgtt gtaaatgaat taatgccttg
     6961 gccaatcagg gtcgtcacat aagaaacgta aggaagcagc ttccagccaa tgtaacccac
     7021 acctgttcca ataataattg gcaacaaaat aatggttaga gacccaaatt tatcaccaaa
     7081 ccacttcact gctaaaacgg caagcgcagc tgtgatcatc atattaatca gatcaccaat
     7141 gccctttagc tggaaggtcc cagtggcaac acctttttgg ataacctctg tataagccca
     7201 agctccagaa ccgatataag ctgccccgcc gacagccagc tgctgcattg ggttaaattt
     7261 gaactgctgt ccaatcaaaa aaccagccat aactggcgta aagaattgga aaacctggac
     7321 gatatgtaaa aattcagctg ctacagtatt tggcaaaagc ggctttaaaa acgtcgctaa
     7381 aatagcattc ggaataagtg caactacaat cgcaattgct gtaccagcta agaccttatt
     7441 cataaacgag ctaaaggtct ctttatttgt tgttgtcatt tcatgacctc tcttaatatt
     7501 atagtgtgaa aaacatcacg aaagtattct aacataaaaa gagcattttg tcacagctat
     7561 tttaattttt atcaatacgt acagaatatt caattaaatg tcatataata ttaatcaatc
     7621 aaggctgttg aatgaacagg tctattatct ctatcaggat aaatatactt aatcgcttgg
     7681 ttgacagcaa tcggtgcctc accaaagcca gtggcaatca aatcaaccct gccttcataa
     7741 gctgctgcgt caccgatcgc aaaaatccct tcctgacttg tttgaaagag gggagagaca
     7801 agaagacttg agcgcttata atctagattc caatgcttta ggtttttatt agatgtagaa
     7861 aagccaaagc taacaatcag gctgtctagc tcaagcgtta tctcctcttc tgactttacc
     7921 ttttgaatag tcattttgtt gacaaagcca ttttctcctt cgagggcaag gggaacaaag
     7981 ggggtaaggg tagtaacatg agagtttttt aacaattcta cgctatgctc atgagcccta
     8041 aaggcgtctc gccggtgcac aagggtaaca ctcttagcga ggccatctaa ggctaaagcc
     8101 cagtccacag cagaatctcc accaccgcag atcacaaccc tcttaccagc aaactgattc
     8161 aagctgtgaa cattataaaa gagattatga tcagcaaata actgctcatt gtctaagccc
     8221 aaggttctag gcgcaaaggc tccattgcca caagcaacaa taatggcctt agaataatgt
     8281 ctggccttgc ttgtttgaat aacaaagttc ccatcagcct tctcaaaaga caggacctct
     8341 tctttcaggc atactgctat gcgatcgtca aatctgctta gctgctcaat aagcttttgt
     8401 gttagttccg ctccagtcag ggccggataa gctggaatat catagataac cttttcagga
     8461 taaagaacag ccggctgtcc tcctagctct gacaggcttt caataatctt aaccgtcatg
     8521 ccgcgcaggc ctgcataaaa ggctgcaaat aagcctaccg gacctccacc aatgatggta
     8581 atgtcatata ttttttcttg cactagttct ctccttcact tagccccgat ttgattttat
     8641 caaaaatcct tttttcctca tcagaaaaat cataagtctc taataaatct ggtcttctca
     8701 aataggtctt ctttaggctt tgctccatac gccagagacg aatatgctca tgatggccac
     8761 tcattaggac atcaggcacc ttcatgccac gataatcata tggccttgta tactgtgggt
     8821 actccaagag cccagatgag aaggaatcct cttgatgact ggcttgcttt ccaagcacat
     8881 taggaatcag tctcactgtt gcatcaatca ttgtcatagc agccagctca ccaccagtta
     8941 agacaaaatc tcccagagat atttcatcgg taacaagtgt cttaatgcgt tcgtcatagc
     9001 cttcgtaatg cccacaaata aaaattaact cttcctcaag agctaattct tcagcataag
     9061 actgatgaaa gggttttcca gcaggatcca gtaaaatcac tcgaggcttt gtagcctgaa
     9121 tgctatccat ggtatcaaaa ataggctgcg ctctcagcag catgccctgc ccaccaccat
     9181 atggctcatc atcaacatgc ctagctttct ccgcatggtc acgaaaattg tggtaatgaa
     9241 tatctaaaag ccccttttcc ttagcctttc caacaatgga gtgctccaaa ggagcaaaca
     9301 tttccgggaa aagggttaaa atatcaatct tcatcatcta agccttccat aatttcaacg
     9361 tctacccgat gcttttcgat atcaacacaa agaacaaccg atgggatata aggaagcaac
     9421 aggtcacgct tgctttgccg tttgaccacc caaacatcat ttgcaccagg ctgtaaaatt
     9481 tccttaatct ctcctactag ctggtccttt tcatacacct ccagaccaat aatctggtga
     9541 tagtaaaatt ctccctcagc tagcttaccc tgattctctt tagcaatctt aagactgtag
     9601 cccttaaatt gctcaatagc attgatgtga tacattccct taaacttgat aatgtcaaac
     9661 tgcttatgct tgcgatgact cgcaatctca acctcctgca caaaacgatc cttgtcgtca
     9721 aacagggcta gtctagcacc tttttgaaat cgttcctcag taaagtcact cacagacagc
     9781 acgcgcattt ctccttgcaa gccttgagta ttgacaatct tcccaacgct aaaatattcc
     9841 atccttactc ctaatcatct tagactctat agcttgatag acctctattt tttcatgaca
     9901 acacgacatg agtatcatca tcctaagcac tctagcctat cgttaaagct ccccttattg
     9961 taacatgttc tgccttattt tgcacttctc tttcaaaaaa ttaatctccc agttatagca
    10021 gctaagccta gcaagcaaag cccttgatgc taaagaatcc tgatccccct ataattaaca
    10081 aatcatcatg acttgccttg cccaagctca gtcaagtgaa tgaaaaatct gctaaacaat
    10141 agccttgcgc ctcgctgaca agcatcaaaa aaacactcct gctggcaatc tgaactgccc
    10201 cccaattgtt agattttatg tccaactttt gggggtcagt acaatctagt aaactagaat
    10261 caggagtgtt tcattatagc ccaacaagca aaaggaatac ttggtaaaag caaagctgac
    10321 ttgcattgag aagattaaaa ccattcaatc tgtcacaata attatggaaa cattgggaat
    10381 ttaaaaacaa gtatcagctg ctatcaacct gtggggaaat agtctaccta tgcctatcgg
    10441 gccatccatc ataggtcctc tcaagaaatg atgagagcct catcaaccag ctatcatcgc
    10501 cttaaaggag aatgacgaat gttatcgtag gtgtcccaag aaatactaca aaagaaactc
    10561 attttgatct taatgctcta aagggcttga ccttacgtca actgataaag ctctacttca
    10621 tagcatcgtt ttgctttgca gcttttctat acctcatgtc taataaaaga cataagcttg
    10681 ccgataagaa cattacccca acatagaaga atagattggt ctcatcgcca gtctttagta
    10741 agatggtatt ttgatgcttc atcggtttgg tagctgttga aacatgcgga cacttggttt
    10801 catttgtcgt cgatggtatt gtcggacgac ttggcttagt gttattaggc ttatgattgc
    10861 cttcactact gcttaccttt ttcttccact gtgcaaacaa ttcattagga aacggcaggt
    10921 cattatctac cctaatgtca tcacctacct tttttaacct cctgctcgat ctcttgttgc
    10981 atacaaaatg ttatacagat acttctgtca gatagagttc ttgcttttgt ctcttgactt
    11041 ggtgattcaa aacacaaaaa aagcctgcta gatagaacta gcaaggcttt aagattagtc
    11101 ttgttcaaaa tagaacttat ttttcatcaa tgactaatcg aacctttttt cctaaagttg
    11161 gcaccgaata gacaatcgat cttatcgctg tgatggtacg acctttcttt ccgataacac
    11221 gaccgatgtc ttgagcatcc aagtcaagat ggtactctaa aaaatccgga gtatcttcaa
    11281 ttttaatagt aagcttatct ggttgtgaaa tcaagggctt cacaatagcg ataatgagat
    11341 tttcaatggt atccataggc ttttattact tagaaaattt ttgatcgtgg aatttagcca
    11401 taaccccagc tttagataga aggctacgaa ctgtatcaga aggttgtgca ccttttccta
    11461 gccaatcaag aacacgatct tctttaagag ttacttgatt ttcagctaca agtgggttgt
    11521 aggttccaac tgtttcgatg aaacgaccat cacgtggtgc acgtgaatct gcaacgttga
    11581 tacggtagaa aggttttttc ttagaaccca tacgagttaa acggattttt actgccattt
    11641 taatatgtct cttttcttta aatgataata gtcaagaaat gtagtcctgc tcatttctca
    11701 cctaactagt atactttact tttgattatg tgtcaagttt ttttcttgac acttttttat
    11761 gatcataata ctactcaaca tcttcaatca gctaagctgc ttagatgaca tcaaacagca
    11821 ggcagctgct cttataagag catacaactc caaactaacc tactctagtg atccttagcc
    11881 gtcaataatg ggatcaggca agcataactc cccgtcaaag gagcggtttg tttcacagca
    11941 aaaaggcgaa ataaactgac aatcacatca aaaaggacga gcccctaaac atgcaggagc
    12001 tcgtcctttt accaatatga cttagtctct ccttgctttt aaggctaggg tattagctaa
    12061 gcgttacact aataatgcat caaaatatgc ttaagaaact ctccaccata aatccaaaaa
    12121 taactgaagg tcaaaattga aatgggtcta caaattagga taatcagtaa aaagcgcttg
    12181 taggtcatct gactcaatcc agtaatcata ataagagcat cggcaggggc taagggggaa
    12241 atcatattga gaataaagaa acgctcaaat aatttcgttg atagcttctt ttcataaaac
    12301 tgtagctgct ccatacttaa aaacagtaag ataaagggct ttccgtatct cctcaccaac
    12361 tgaaacaaaa tagaagatcc aatgcagata ccaaacacat ttaacataaa gcctaatata
    12421 ggaccaaagg ctagaaagcc aacgactgtt gtcacaccac caggaatgat aggaacaact
    12481 acctgcacaa tttgcaagat aaaaaagcaa atggcaccga taaggagatg atccttgatt
    12541 aaatgggcta aagcctttgg attattaata atatctagct gcctaataag gtagacaaca
    12601 agcatgacgg agaacagaat tgataggcca ccaagaatct taaacagctt ctttaacaac
    12661 gaatgtgaaa caccaaagct actcatagcg caaagcctct atcggatcaa gcttgcttgc
    12721 tttgtttgct ggcagcaatc caaaaataat accaattgat gccgaaaaga taatagctac
    12781 agccgcaaca tctaaggaaa cagctgctcc ctttaattgc atcgcatttc ctagcacacc
    12841 tacacacatc tgtgctagca gcagccctaa aagaccgcca attaacgtca acaccactga
    12901 ttcaatcaaa aattggctaa gtatcttcaa gcgcgttgct cccaaggctt ttcgcaagcc
    12961 aatttcacgt gtacgctctg ttacagatac cagcatgatg ttcataacac caataccacc
    13021 cacaagaagg gaaattcctg caatggaccc aacaactgtg gtcatgatac taaattgtgc
    13081 gttaatgtca ttgataattt ggctattgtc aggaacagcg tactcgccct ccttaacatg
    13141 agacagtgtg gtcagcatag cagctgcttg atttcctaat tcaaggcttc gcttaacgtc
    13201 gccaatataa agataaacag agccaatttc cttgacatga aattctgaag ccacctgggt
    13261 attggccata atggctcctc cagaaatccc accagcaaac gaaacaacct cctgatcagt
    13321 cttgtaaaca cctactacaa ggtagtcctt actatctaga ctaaccacct tatttagagc
    13381 ttgttcataa ttgcctttgc caaataattc gtcagccaag acagtatcta ataggataat
    13441 gcgagaaaaa tttttataat ccttgctatt tagcgtccta cctgcaacaa tatcatattt
    13501 tttgacttta aaataatcct gactaacccc agtgatggcc acattgtcca tcttcttttt
    13561 ctcaaaggaa atggtagagg ttgaattatt ggtatagtaa taagaatcta ccccatcaat
    13621 tgctttgaca atctgctcta gccattcagg cttgacctct tgctcatttt catgcgctgc
    13681 aaaggccgcg taagggttgt cctcatctcc ttttgccttg aaataaagct gaacctcttt
    13741 ttggtcattt gaaaaggaat ccgtaaccct ctttgtcatg gcagcaccaa gccccatgat
    13801 aatcacaaca gcagctacac cgataataat tcccagcatg gtaagaatcg aacgcagctt
    13861 gtgcccccag attgaactaa gagcaaattt ccaattttcc atcacttttc ctcctagtca
    13921 atcctgacac tttctgttgt atcagctgtg atttcaccat cacgaataac aatttttcga
    13981 gtggcaaagt ccgcaatctc tggctcatga gtaaccataa taatagtttt gccttcctta
    14041 ttcagctccg tcaaaagcct cataatctgc tcaccagtct ttgtatctag ggcaccagtc
    14101 ggctcatcag ctaagataat agacgggtta ttaaccaagg ctcttgcaat ggcaaccctt
    14161 tgcttttgac cacctgataa ctctgatggc aaatgcttca ttcgcatacc aagctcaacc
    14221 ttttccaaaa attgcttagc caattcacga cgctttgata ctccaactcc agcataaatc
    14281 aagggaagct caacattttg cagggcattt agctttgcta gtaaaaagaa ctgctgaaag
    14341 acaaagccaa tctcttcgtt tctcacctga gcaagctttc gatcatttag gatctcaacc
    14401 tgtgtgccat tgagacgata atcacctgag gttggtctat ctaataagcc gatgatattc
    14461 atcagggttg atttccctga gccagaaggc cccataatag cgacaaattc accctcatat
    14521 acagtcaaat ccacgccttt taggacctgt agctcctgat caccattttg atagctttta
    14581 acaatgcttt ttaattgtat taattctttt ttctcatctg gcactactta atcacctcgg
    14641 attctttact gcttttttta gaatcttttg atgcctttgt gtctgcggaa ataacgtctt
    14701 ctagcttttc accctctttg atgttcttat cagggttagc aatgacaata tctcccacct
    14761 ttagacctgc acttacttct tgtctttcag catcagcatt gcctagggtt acttcaacct
    14821 ttttagcctt tgcagttgag tcatcataga cccagacaaa atgcttcttg cctttgttaa
    14881 cgatagcagt aactggtact aaggcatgct ttgcttcgtt gataacctca acagacaccg
    14941 taaagccttg ctttagctgg ttaagcggac tcgtgatatc aattttgtag tcataggtcg
    15001 caccagttga gcttgatgag cctgagcctc ctgcagttga accacctgca ttggcatcgg
    15061 ttgggtagtt tgacacataa gaaatctttc cggtccactc ttgatcagca tagacctttg
    15121 atttaatctt cacagcttgt ccaaccttaa tattggctaa atcatactct gttagggtcc
    15181 ctttgacctg taacttgcct tcggttgcga catgaaccaa ggtttgactg ttttttgaag
    15241 acgggtcaat atcattatta acctctacaa ctgtccctga aacaccactg acaactactg
    15301 tttcatttaa ggcctgctgt gctttattga cctctgcttg agcatcagca taggaatcat
    15361 ttaaatcctg caattgctga gcatagctag cattttgctg ggctgagggc tgaatggttg
    15421 tggtggtttc ttgccctgtc tcctcgtcct tgcttgtctc agtagttgct gctggaacac
    15481 catacgtttt taaatgatta atctgacgcc caattttatt gagattgcga acagcggtgt
    15541 cataagctgc ctgtggtaca gttgtattgt actgtactaa ctgctggcct tgtgtgacct
    15601 gatctcctac cttaaccgta acggtagcgt ctgagccttt gctagcatca aaataaacat
    15661 attcttctga aagagcttta acagtaccag agagtaaggt tgaagaggct attgtccctt
    15721 ctgttacatt taccgcagaa taaggtagct tgatattttg atcagagata gtatcttgct
    15781 gttgcttcca caatactcca ccgataacga ctacagttag tgcaactgca cctgcgataa
    15841 tgcctttggt tttcgttgat aactttatct ttcctctttt agacatttct gtcctcccct
    15901 tttgtactat ttttgtaaga caagtatatg atgtttttaa aaacttgtca agaatttctt
    15961 ggataagctt aataaagcag cctcttcatc atgtagatga caactctatt ataatggttt
    16021 ttcaagctgt actagcttac acttttgtaa tattaaaaag aggcaaagac aaaaagagtt
    16081 gtcctttaac tttattacac agtctcattc attaaaaagc gaacaagcct agttttcaaa
    16141 atctcagaaa actagacttg ttcgtttgtt tagacttttc tctcagtctc ttcatcaggt
    16201 ttaaatagct tctatactaa aggtacggct ttcaagaact ctcagcattg ctactgctgt
    16261 atccaatgct gtaaacagag gaactccttg ttcgattgct gagcttctga tcatctgccc
    16321 gtccttatca gtcactcgtt ttgttcctac ggtattaata atagcttgaa tctgcccttt
    16381 tctcagtaag gctgggatat catgagcatt gtcgccaatt tttccaacta gctgtgaatc
    16441 tagcccttgg tcagcaaaga aagcagctgt gccttcggtt gccatgatct ggtagccaat
    16501 agcactaaag cgtctagcta agatcagagc ctccgactta tggtcatcag cgatggtaaa
    16561 aactattgtt ccatattccg gcatgtgcag atagctagct tcaaaggctt tgtaaagggc
    16621 tttttcaagt gttaaatcag agcccatgac ttcaccagtt gatttcatct caggccctaa
    16681 aaggctatcc accttagcga gctttgcaaa tgaaaaaacc ggtgccttga tatgaacaag
    16741 cgagctttca ggataaaggc catcttgata acctaagtct tttaaggtct gacccagaat
    16801 aagcttcgta gcgacttgtg ccattggaat attggttact tttgataaaa atggcactgt
    16861 ccgactggca cgaggattga cctcaatgac atagacctgc tcattttgga tcacaaattg
    16921 gatattcatc atgccaatac agtttagccc tatagcaaga cgcttagtgt aatcaacaat
    16981 cttgtcttga acctgtttag ataggtgctg cggcgggtac acagccattg aatctcctga
    17041 atgcactcct gctctttcga tatgctccat gatccctggg attaagactg attgaccgtc
    17101 agagattgca tctacctcgc attccttacc aaggatataa gaatctatta aaacaggatg
    17161 ctcaggacta gccttgacag ctgttttcat gtaggagcgt aaatcgtttt cattttcaac
    17221 aatttccatt gctcggccac caagaacata agagggtctg accaataccg gaaagccaat
    17281 ggcacgcgct gcctctaagg cctctgcctc attggtggct gttttcccag gaggctgagg
    17341 gatccccagc tccttcaagg ctttttcaaa aagctcccta tcctcagcac aatctaagtc
    17401 ctctagctgt gtgcctaaaa taggaactcc ggccttggtt aactgctctg ctagattaat
    17461 agcagtttgt ccaccaaact gtaggattac tccctttggc tgctctaatt caataacgtt
    17521 catgacctct tcaaaggtta agggttcaaa ataaagcttg tctgatatcg aaaaatctgt
    17581 tgacactgtt tcaggatttg aattcatgat aatggcttca tagcccgcag cctgaatagc
    17641 cttgacagaa tgtacggttg cataatcaaa ctcaactccc tgaccgatgc ggataggacc
    17701 agagccaagg acgataacag attctttctc ggatttgatt gattcgtttt cccactcata
    17761 ggtcgagtaa aaataaggcg tttgtgagtc aaattcagct gcacaggtat caaccatctt
    17821 ataaactggc aagacacgat aggctcgcct taaccgtcta atacttgcag catcagtttg
    17881 ccaaagctct gcaatttttt ggtctgaaaa accatatcgc ttggcttcta tcagcaaatc
    17941 gatatcaact ggctttttaa taaggtcttg ctccagttct acgatatgac gtaatttatc
    18001 caaaaagaat aaatcaatct tggttaagcc agctagctct tcaatactat agccacgacg
    18061 aagggcctca gaaagataga atagacgatc gtcctgtgct cttacaatgt gagcaaccag
    18121 ctcatgatca ctgatagtat ctagaccctt cagttcgtta tggtgtactc caatttccaa
    18181 cgagcgacaa gcctttaaga gacattcctc aatacggcgt ccaatagcca taacctcacc
    18241 agttgctttc atctgggttc ctagacgacg ctccccccgc tcaaacttgt caaatggaaa
    18301 gcgtggcagc ttggcaacca cataatcaag agctggttca aacatggcat aggtggttcc
    18361 tgtgaccgga ttaagcatgt catcaagcct taagccaact gcaattttag cagctatttt
    18421 agcgattgga taaccagttg cctttgaagc cagtgctgat gagcgagata cccgcggatt
    18481 aacctcaatc acataatagc tgaagctatt gggatcaagt gccagctgaa cattacagcc
    18541 tccttcaatc ttaagggcac gaataattct caagctagca tcacgaagca gctgattctc
    18601 aacatctgat agggtttgtg tcggggcaaa aacgattgaa tctccagtat gtatccctac
    18661 tgggtcaaaa ttttccatac tgcaaacaac cagcgcgtta tcagcagcat cacgcatgac
    18721 ctcatattca atctctttaa agccggcaat ggagcgttca atcagacact gggtgacagg
    18781 agatagcttc aggccattct ccacaatatc tcgcaagacc tcttcattgg agcaaatacc
    18841 acctccagtg cctcccagag taaaggcggg gcggacaata acagggtagc caatggcatt
    18901 tgcaaagccg atagccgcct ctactgtcgt cacaatctct gattctggaa taggctctcc
    18961 caactctttc attaattgct taaataaatc acgatcctct gcctgatcaa tagcagataa
    19021 ggttgttcca agcagctcca ctcctaattc ttgtaaaata ccagccttag acagttccat
    19081 cgccatgtta agaccggtct gcccacctaa ggtcggcagc aaggcgtctg gtctttcctt
    19141 tcttaagata cgactaacaa atgccaacgt caggggctcg atataaacct tatctgcaac
    19201 ctctttgtct gtcataattg tcgcagggtt agaattaacc agaacaacct gatagccctc
    19261 ttcctttaag gctaaacaag cctgtgttcc tgcgtaatca aattcagctg cctgcccaat
    19321 aacaatagga ccagacccta tcaccatgat ttttttaata tctgtacgtt ttgccataat
    19381 atctggtaca aaaggcctta acaatccgaa taaaataatg caagcaccta acattaaagc
    19441 atcacaatct attttttact aggatttgta cctgtactca gctgcagcaa gccctttgta
    19501 cctactcctt tcattatttg ccgtctcaca gggcggcatt aaataaaaca cttaacagtc
    19561 tgtcacatga gacgatgagt acaagatcaa gtaaccctta gctcagcaag tatagatgac
    19621 ttaattgata tagtcttttt acttctaaag agggcgatct tgccagcaaa tactagtcat
    19681 aacccgcggc agagcgatca tttcccacta gtctatctgc tgcctgactc aagctgtttc
    19741 atgacagctg atcaagcctt tggtgcttgc tttttgatct gctagcacac ttgattaaca
    19801 tttgccttgc tgctctagct gccaggcgtc aatcatatct aaaaattcat caaatagata
    19861 gctagcgtca tgagggcctg gtgcagcgtc tgggtgaaac tgcacagaaa aggcgggaac
    19921 atgtcgatgt ctcacccctt caacagtttt gtcattaatc tcctcgtgcg taaccatcaa
    19981 gcagtctggc aagctgtcgc gctcaacagc ataaccatga ttttgactag taaaatcaat
    20041 acgtccggtc gctatttctc tgacagcatg attaaagcca cgatgtccaa aaggcatttt
    20101 aaaggtctta gcgccattag ctaagctaag cagctgatgg cccatacaaa tgccaaaaat
    20161 tggaattttt ccttgaacac cacgaatcat ctccaaggcc tccggcaaat cctctggatt
    20221 acctggacca tttgatagca ttagaccatc tgggttgagc tgtagaatct cttctgctgt
    20281 gatatcaaag gggactattg tcatctgaca ttgccttttg gataattctc ttaaaatgga
    20341 atgcttcaag ccaaagtcca ccaaaacaat atttttccca acacccggag cgggataggc
    20401 agtcttagtt gacacctgct caataccatt agtcggaagc acagttgcac gcagctgatc
    20461 ctttaggtgt tcaagcgtat caccatcatc tgccattgtt gccttcatcg taccatgctg
    20521 acgaatgatt ttggtcaacg ctctggtatc aattcctgaa atgcctggaa tccccttatg
    20581 ctttaaaaac tcgtccaagg tcatttgctg acgccaattg ctagctatcc tgcttacttc
    20641 agagacaatg acccctttgc aagttggggc aatggactca taatcatcac gattaatacc
    20701 ataattacca acaaggggat aggtaaatac taagagctgc ccgttatagg actggtctgt
    20761 gattgactcc tggtagcctg tcattcctgt attaaagaca atctcgccag tgacatcaat
    20821 atctgcacca aagggctttc cttcaaaaat ggtgccatcc tctaagataa gtaaccgttt
    20881 tgccatttta accccctcta acatgccttt agaccttatc gtttctgcca ttaaggatcg
    20941 cttcgataat ggccatacgg acaaatacac cattagccat ttgagctact attcttgcct
    21001 ttggagcctc tactaaatgg tcagcaatct caacatcgcg attaaccggt gccgggtgca
    21061 taataatcgc agagtccttt aaccgcctgt agcgctcctc agttagacca aactgtctat
    21121 gataatcttc cttggaaaag ctttgactac catcatggcg ctcatgctgc accctaagca
    21181 gcatcaacac atctaattga tcaataatgt gatcaatcgc catgtacctt ccatagctgt
    21241 caaattcaga cgagtaccat tgctcaggac catagaaata aagctctgct ccaagccgct
    21301 ttagaatctg catgtttgat ttagccacac gagaatgtgt caaatcccct gcaatagcaa
    21361 tcttcaggcc atcaaaatga ccaaattctt cataaatagt tagcaaatca agcaagcatt
    21421 gactagggtg ctgacctgat ccatcacctc cattaacgat agaggcagta atcgttggac
    21481 tgtcaataag ctgctgatag taatcatctt ctgggtgacg aatcacgcag atttctgttc
    21541 ctagagcact catggtaaga acagtatcat ataaggtttc ccctttattg acagcacttg
    21601 tatcagcgtt aaaatcaagg actctaagac caagcttgtt ctcagcaacc tcaaaggatt
    21661 tatgggttct tgttgaattt tcaaagaata aattagctgc aaagtgccta ctgttatctt
    21721 taatagctac cttacctgcc ttgtattcag agccacgact aataagtcct aaaacctctt
    21781 catttgttaa atgctccatt gacaccaaat gcttaagcgc aacacgatta tttacaactg
    21841 acatgattta tcccctttta ccaataatga aatgatgata acaattgaca acagctacac
    21901 actagttttc tggaagaagc tgatacaata taatgccaag aagcgttgaa aaagcaacac
    21961 ccgaaatctg aaggccattg atttgaagca tgaggcctcc aataccagaa accagaataa
    22021 cactagcaat caataggttt ttcttgttgt ccatatcaac cttagcttca atcaggattt
    22081 tcaagccact agaggctata accccaaaca gagcaatcga aatccctcca atcactggag
    22141 taggaataga ctgaataagt gctgatacct taccaacaaa gcttaacaaa ccagcaatca
    22201 cagcggcacc tgcaataaca tagactgaga agattttatt gagggccatc acaccaatat
    22261 tttcaccata agatgttacc ggaggcgctc ctaaaaatcc agcaatcacc tgtgcaaggc
    22321 catcacccgt caaggttttt tccaagccag gatccttgaa ataatctctt ttagtcaggc
    22381 tattaagcac catgatatga ccgaaatgct ctgtcatggt gacaaaggca atcggggcca
    22441 tcgttaaaat agcactagga tacaaggtaa tgtcataggt taaaaagggg atagccacag
    22501 ctggaacact gagccattgg gccttagcaa cctgtgtaaa gtcaacaata gactgacccg
    22561 tcaccatacc aacaaggatc gcaaacaaat agccaaccaa taagcccaac aaaataggaa
    22621 tgatggcgac aatcccttta ccataaatgt taaagaaaat aatcgctaat aaggtgacaa
    22681 gaccaatcaa aaggtataac aggttatact ttccatcctt tagcatgaca tcactaactg
    22741 ctgttgaggc caagctaaga ccgatcacca taacaatggg accaaccaca actggaggta
    22801 agatcttatc gatccattca ttgccaatcg ccttcaccac cagtgctaca accagataaa
    22861 ccaggccacc tgtaatcgct ccctgtgcaa ctgcaccaat accatctgtt ttcattagca
    22921 tttgcatggc tgcaatataa gcaaagcttg agcccatata agcgggaatt ttaaatgttg
    22981 ttactgacaa atgcgccaga gtcccaagtc cacttgataa gagggcaact gacggatcaa
    23041 tcccaaccaa aattggaacc aaaacagttg ctccaaacat agcaaataaa tgctggaagg
    23101 acaagccaag caaaatccct gcctttggca cttcttctac atcataaatg acatctttca
    23161 cacaatcacc tctttcttat cccggatcaa caatactaat acgatcttga ccgtcaacct
    23221 caaccacctc aacgacaatc tcttctgtct tgcttgtggg aatattcttt ccaacataat
    23281 cggcccgaat tggtaattca cgatggcctc gatccaccaa aacagctagg ctaacacgtc
    23341 caggacgccc taagctaacc aaattgtcga tagctgcccg aatcgttctg ccggtataaa
    23401 gcacgtcatc tactaagata atatccttgc cggtaatatc taccggcatg ctggtggtgt
    23461 cctcttccac tctcatatca tctctaaagg gcttggtatc tagctctcca actgccaagt
    23521 gcaggctttc tagctgctct aatctttctt gaatacgacg agcaaggtaa acacctcttg
    23581 ttttaatccc tacaagcacc acattgtcta gttgcttgtt gcgctcaata atctcgtacg
    23641 taatccgcgt gatcgcacgc ttcatggtta gctcatcaac aattaccttt gatttcattc
    23701 aaagcctcct caaaaaattc aactaaaaaa atctccctgt taacaaggag attcagcaaa
    23761 acaggcacac agctagacat aactgtgcac ttttttattc agaacatgct ccttgccagc
    23821 ctcacaggac tgttttaaag gaatatttta ttttcattag tatagcaaaa tcacaagcca
    23881 aaaacaagga ttttctaaaa aataattcaa aatatataga gctatcacag caccaaggaa
    23941 aatgctacta aggtcatcag caatcctcca acacaattcc aaaaataggt cttaagacct
    24001 attgtatttg tatcaaaaca atagtacaat aatatcaaac acaaaggaga gcgtttatga
    24061 tgaatgatat aactagaaag attaaccata agcaactgat tcaaatcact accattctag
    24121 gcattattgt taccatcgtt attttgttct atctgcagca gcaccctaat ctttttgcag
    24181 ttggcggtcc ttttcagacc tatcttatgg aacttggtat cctagcaccc tgtttgttta
    24241 tactgcttca aatcattcaa gtggtttacc ctatcattcc tggaggcttg acctgtgttt
    24301 tagggcatgt agtctttggg ccgttttggg gatttcttta taatactcta ggtattttta
    24361 ttggttcgct gcttagcttt atgctcgcta gaaaatatgg tgaacagttt gctaaagcct
    24421 ttgtatcaga tgatacctat aacaaataca ttccttacct caataaaggc aagtactttg
    24481 aacgatttct cataacagcc tttattctcc ctggctttcc agatgatttt ctctgtatgg
    24541 tagctggact aagcagcatg tctatcaaaa catttaccag tattttcttg atatcaaagc
    24601 caattactct ttatatctac acccttcttg cttaccaagg catacaaatc gttggacagg
    24661 tattgcaatc ctaaaaaaag ctagtattaa gctatcaagc ctgattggaa tacagtattc
    24721 caatcaaaaa ggcgctcagc ttggtaccag ctttttatcc ttgtcttagt tgctccaaag
    24781 tcctttggaa gatttctggt ggctcaacag taaagaccag ctcctctcct gtcacagggt
    24841 gggttagtcc caatgtttgc gcatgaagaa actgcccctt gccagccaag gtcttacgag
    24901 gaccgtagag tggatctcct gcaagagggt gaccaatata agccatatga acgcgaattt
    24961 gatgcgttcg acctgtttcc aattgtaatt ccacgaaggt atagtggcca aagcgctcca
    25021 aaaccttaaa aagagtcaag gcttccttgc ccttagcagt tacggtctgt tttttacgat
    25081 ccttttcact gcggccaatc ggagcttcaa ttacacctcg atcctttggt aaattaccat
    25141 gaacaatggc cacatacttt cgtaaggatt tcttagcctt gagctcatca gctagtagct
    25201 ggtgggcctt atcggtcttg gcaaccatta aaagaccaga ggtatcctta tcaattctat
    25261 gcacaattcc tggacgaata acaccattaa tagaagacag gtctttgata tgatagagca
    25321 aggcattgac cagcgtccct gtagaatgcc ccgcagaagg gtgaacaacc attccctgag
    25381 gcttattaat aatggccaat acatcatctt ggtagacaat atctagtggt atatcctgag
    25441 cctgatagtc caagctgctt tcctctggga tatgatagct aatgcagtca cccacctgca
    25501 caatatactt ggccttctta ggtaagccat tgaccaatac ccttttttgc ttgatctgat
    25561 cattagcctg acttcttgat aatggggtca aatcagccaa ggccttatcc aagcgatggc
    25621 ctgattctgt tatcttaatt tccatagtcc tcttctttcc atagacaaat gaccagcagc
    25681 aaaacaccta tcgtcaaata ggaatctgcc acattaaaaa tagcaaaatt gatcacatct
    25741 aaatgaatca tatcaaccac ataggataac ctcaagcggt caataaaatt cccaagacct
    25801 ccagatataa tcagcaataa agagagctgt agccaaaagc tagcctttgg gtgcttcaac
    25861 acataataaa tggcatagcc aaccaccaaa acagttatga ttgtaaagaa ccactgctga
    25921 ttctgtagta tggaaaaagc agctcctcga ttttgaagat aggtcaagct caccaaacct
    25981 ggtataaagg gcttcacctg ccctagctca atatgtgtaa cagtccacca tttacttagc
    26041 tgatccagta tcattaagac aatggcagcc ataataaaac taattctttt caactaatcc
    26101 tattcctttc agcttaaaaa caagagatta ccttgatggc ttcaaaaaag caacaacagc
    26161 cagctgtctc tgtagcgtac tcaaccttaa agcctccaaa aactggtatt ctagtaacct
    26221 tttagtatca ttgatagtca accacacagc agctctagac ttgactttat atcaacaagt
    26281 ctcaccacag cagctcgctt aatccttatc cataccagag ctaagtccca ttgtctatag
    26341 cttgcttttc ttttcgatgt tcaaaataat cctgtaaaat ggtcacaaaa tgtaaagccg
    26401 cagcagatag gttcttatcc ctacgcttga cataaatcat tttatgctcc atatgatcac
    26461 gcaagggaat aaccttgatg ccattaacgc tttgctgatc taaaaatcca gaccctgttg
    26521 caaaggcagc tgtcctttcc aaaatgccat ttaaggttgc cctatctgac acagtgtata
    26581 tgtgaggact cttgcttgtg tcaataaaat tttctgaata ataaagatat tcttcttttt
    26641 cttgagtaaa gcgtaccgct ggcagccctt gcaaatcctc taagaaaagg gctttccttt
    26701 gagccaatgg atggtttttt gataggtaaa tatgggttgt aaaggatagc aattcaacat
    26761 aatccaaagc cagcttatcc attcgctgaa aaagcccctg acggttttgt gcattaagat
    26821 agataattcc aagctcacta tttccctgtg ccacctcatc taaaatttgc atagtcgttg
    26881 actcaaaaac tctaaaaacc ttatgcccag catgcttttg ggaaaatgct gttattaaag
    26941 ctggtaaaaa atcataatgc tgactcgcaa ttgaaaattc atttggctcc aaagccgatt
    27001 gagaaaactc cttttccagc gagtcaaagc acttaacaac ctctaaggcc ttttcataaa
    27061 ataaaagccc ctggctggtt aacacagttc ctgctgttgt cctacgaaag atctgaaagc
    27121 caagctctgt ctccaaatcc ttcactgaaa cagacaaact gggttgactg acaaatagct
    27181 ttgaagcagc ctcacgaaag gtaccattat ttgcaatagc aaccacatat cgtaattgtt
    27241 gaatattcat taatccactt cctaaatcta gtacccttca ttataccata aagccagcca
    27301 atgaaaaata aaggcgtcca tcttaaccat gccaaacgta tctacagata atcatgagat
    27361 agcattgact ttttcaatag tgtcttatca tatttagcta tagaaaacag ccttactata
    27421 agttatactt ttgaaagaag taagccttag atcacagaac atcacactga gattttttat
    27481 gcgcttatcc tgtctgtcca agaactgaga attggctaca tctagctaat aagccatttc
    27541 aggattttac tgtctaggag ttatttatag gcaactatta cagtaagata gtgtcacaat
    27601 acaaaaaagg ctatcccaaa gtacagaaca gccttatacc gtgccctttt aacacattat
    27661 tttgcgattg ggtatacaga aacttgtttc ttatcgcgtc ccttacgctc aaagcgtaca
    27721 acaccttcaa ccttagcaaa aagagtatca tctccgccac gaccaacgtt aacaccagga
    27781 taaatatgtg tgccgcgttg acggtaaagg attgaacctc ctgaaactgt ttgtccatca
    27841 gctgccttag cgccaagacg ttttgcttgt gaatcacgtc cgttagaagt tgaacctcca
    27901 ccttttttgt gggcgaagtg ttgtaggtta gaaagattaa gtttaatcat ttttatttcc
    27961 tctcgttgaa tttaattcat cacaggcttt tgaacatatt ctgataaatg ctctgccaaa
    28021 ttctccaagc caatcacaac agactcaaac agaatttgcc acacctgctc ttgttgctca
    28081 gtaaatccct caggctttgt tacccttagg aatccaccac catcgaccat ttctagtgct
    28141 ggctcaagac ctgtcatctg ttcaactgaa ttaacaagat tgaaggccaa aactgaaacc
    28201 gaagcacaaa ctacatcaaa gccgtactca ccgcttccag catgtcctgt gataagcatc
    28261 tcagtccagc cagctgcgtc ttttgttaac cgtactttaa tcatgtcaaa ctagaattat
    28321 gccttgatag cgttaatcac aactttagtg taaggctgac gatgaccttg cttacggtgg
    28381 ctaccttttt taggcttgta cttaaaggtt acaaccttct tttgttttcc ttgcttttca
    28441 acagttccaa cgacagtagc tccctcaaca actggagtac caacgacagt cttatcacca
    28501 cctacgagaa caacctcgtt aaaagtgatt tctgcgccag cttcagcgtc aattttctca
    28561 acgtagattg cttgacctac ttcaacttta acctgttttc caccagtttt gatgattgca
    28621 tatgtgctca tgatgcacct cctataagat ttttgatgag gtttccctct gtgaagactc
    28681 gcctagaatc gtgagagcca atctacttga aaacgatttt cgtgcggttg cacaggacgt
    28741 gcacttagtc aacgttacaa ttttaacatc aaatttgatt tttatcaaga aaaatatgct
    28801 tttatcttcc taaaatctta agctatacat aatcacagct atgtaaaggc tagcaatgct
    28861 ttaccatttt aggttaacca gggcattcat ttctttataa gcaatagctg ctttttcttg
    28921 cgtttcggga tcaatcttat cataatatct gccgcctttg ataaagtcct ccaaaaccat
    28981 ggtacgatag ctatatagct catagccttc actaccataa aggcccttag gcttagctaa
    29041 aaccattgtc gggtgagcct ttactgtttt tatttttgtt ttttgcccct tcttctcaaa
    29101 ggtaaggtcc attagcacgc cgcgctctgt ccaaatatca tcaacagtct ctaggcgttg
    29161 attggaaatg aaattaccca ttgaatagat aataaatttc ttttccttgt ccttaacaat
    29221 cgtctctgcc ggctctacga cgtgggggtg acctcctaag acaacatcag caccccagtc
    29281 aatcattttt cgataaagag ttttttgctc agctgttggc tctaaagcat actctgtgcc
    29341 catctgcggc ataacaatgg taatatcggc ctctttttca gcacgcaaga tgtctttttg
    29401 tatcttttcc tcattaaggt cagacaggtg cttgtcatac tcctcctgac tgagtgtcgc
    29461 ctccattcca ttatagccat atgaatagcc caatattgca atcttaatcc cattaacctt
    29521 tttaatgaga atgttctcct tagagcgatc ctgctcataa ataccaatgc tgtctatccc
    29581 catatcagca aaaacacgct tggtattgag agctccttct aatcttgagt ccaaaatatg
    29641 gttatgggcc aaatcaacca catcatagcc agtatgctta agcgcagcag caatagcctc
    29701 tggcgcatta aacaaaggat agccagctag aggatagtct ggactgatcg ttccctcata
    29761 gtctccaatg gccaaatcag cctgactaat ccaatccttc acatactcaa aatagggatt
    29821 aaaatcatag ctaccatcag cctttttagc actcatatag agaatatcat gaatcaaaat
    29881 atcaccattt gcgacaacac gcgctgtttg tgtcttttga ggtgtcttgc ttttcgtttg
    29941 tgtgcctttt tttgacatgc ctaataaatc aaaggccaac ccaaaaacaa gtatcaccac
    30001 aatcaaggta agcactgaaa gcatggtctt tttatactga aaatctttta gcaagcgtca
    30061 aacctccttt tttcctatta taccatgttg acacgacttt ttaataacaa atcccaaaga
    30121 aaaggctatg cccatttaag aagaatgcct tagacagcag catagactcg tattagctag
    30181 tcaaaaaact agattgctcc tctttggttg atgtcatata ctttgagcct aaatagcttt
    30241 caacaaagtc taatagttga ataatgtcat gcaaaatatg gtataatgaa acaaaatcaa
    30301 actagtcagg atagtcacat gaagcataac tctttcagcc gctcactatt actccccctt
    30361 ctcatctgtt ccttgtctgc ttgctcttct catacagaga aaaaagacca taccaaagac
    30421 gctactgcta tcaccgatac ccgaaaagca gagcatcagg acatcagggc aaatatggaa
    30481 aaggtcaagc tcgctaccgc tagcaccgac ttcaaaggtg gctcaagcct tgaggagcta
    30541 atcactattt ttggacagcc tagtcagcac gaagaaaaag cagctggtag tgttactctt
    30601 gactcctaca catggcagtt tgaccatgtc acggttaata ttaacctcta tgaaaacagc
    30661 agcattgtta aaactattgc taactttgct tttattagag acctgacctt atccttaaag
    30721 gactacaaca gcttgaaaaa gggcatgacc tatgatgagg tcaagcagct attgactgag
    30781 cctgataatt acagtcaagc caattccagt gaaaaagaaa ccattcaagc catttggatt
    30841 agtggcttaa aagctcagac acagggtgcc aatatagcac taacctttga aaacaaccag
    30901 ttgacagaaa tgtcacaggt tggtcttgaa gactagtttg tggataaccc caatcatatt
    30961 aatgatagaa aaaagcttga tatttaataa gatcaagctc aaacgataga ccaagtagct
    31021 gatgatcttg acagtaatgt gtaacaagct gagatactac tcactaggca gtatttacta
    31081 gcagccactg aatttccttt atgatgacag gcaaccacct tttttgtggt gacctatcaa
    31141 tagcaccata agctctcttt tgtcacatac cttgcttaac attattttac caggtatgtg
    31201 atgagctttt taggttgtct gatagtataa catctaaccc ctagttgatg atgtagataa
    31261 ggcaagagct gctaaggata gcaccataaa taagatccaa catagggtca tattatatag
    31321 tgccaagaac gaaaagataa agacacctac agggagcgat aaagagaaca gaagacctaa
    31381 aaagttattg ctttgggcta gcatatctga tgggagattt tccattaaaa gggcgtccag
    31441 cttgggtgtg gcttttccca taatataagc tgcaaaggct aagcataaaa cccctatgat
    31501 ggcaggtaat tgcagagcat tagagactcc taccagcaaa aatgctatgc cctgagtctg
    31561 tactagcttt gatattgaaa gccttgaaaa gtaatccttt ggtgttagat ttcccaacat
    31621 cgctccgata atcgtaacgg catcaacaat aactaaagac tgcccataat gaaaatgaaa
    31681 tagctgatga tccatcaaat aaaaatgata aatgctatta attgctcctc caatagcgtt
    31741 taaggtcaag atggataaga gtaacatcac aaaagagata tgatcaatct ttttaaaggt
    31801 ctctgtcatc cttgtataca tcaccttaaa ttgcttcatt aatgaaacac ctgcttcaga
    31861 agcttcaacg acatcatgcc ttagcttttg tcgattttta agaagcacaa cagatgacaa
    31921 taaaaaggaa atagcattta tcaaagcaac aaaggcataa ttgttgcctg atgtcgttag
    31981 cagccaaact cctaaagctt gtcctgcaat actagagagg tagccgataa attgagcaaa
    32041 agaataggcc tcatagagct tttctgattc aatatttttc tgcattatcg ggagacgtaa
    32101 gccatttttg taatcactta gaatatcaga aaccacattc aaaaagccca caaaggcaaa
    32161 taccaagaac gtctgatttg tcatcaacaa ggctacaagc gtaaataaaa gagattgtat
    32221 aaaaccaata acaataagat ttcttgtttt cctttttgtc ttatctgctt tgacgccaat
    32281 ccaaaaggta aacaccatag gaatgatggt gatgatattg gctataaaaa cagcaatatg
    32341 agaataaggt agcgtggttg cataaataat aaaaacaata ttgtaaatat aagagcctaa
    32401 agcacttaaa aagtttgaaa ctgtcagtgt tctaaaaacg acatttttaa tcaatcccct
    32461 catttactta cctgttgacg tcctttctta tgtcacctta ctttacttga ttgaatatac
    32521 ttacagcata tctaaattcg tactgtagtt ttatatggtg ttctgacatg attttgctac
    32581 taattagtaa ttcacaagcc ttttctaagt ataaagtatc gtttgttagt ctaaatactt
    32641 gtaaaagtgt catggctatc cccagcattc cgttccatag accactaaac tgagcaaatt
    32701 caactaataa cgactccgat aaattcttaa tatctttaat atatttatcg gagttaacgt
    32761 aaataagcaa ttgaacgatc ccagcagtcc catttgataa gtatggagat acagaatttt
    32821 ctgatattaa tacaccccga tttccatcgc tatcttcaac taagctttct agaataaaat
    32881 caattccttt ctcaataatt tcgttatcat aagaaattga agacagatag aacaatactc
    32941 cagctaaacc atttaaccct aaattaactt ctgattttaa ttgcatcaaa acttcatcgg
    33001 atttatccaa aatcttatta tatttagtaa ttagtgtgtc ttgtaaagaa ataatattaa
    33061 caagttcttg attccaatca tcagatattg caatattagt atttaattta taagtacatt
    33121 gaaaatgata agaatagatg tcgttcctga tcatattaat agcctcttcg atgtctgaat
    33181 tctcactcaa aagatactca ataagcttat aaatattaga atttatgccc ttttgtagta
    33241 ataggttctt taattcacca gttagtatat tattatctct tatgtgtaat ttccctagta
    33301 gatataaaaa taagttccca attttataac aatctgcaac cttcccatct acatcattcc
    33361 attctttcaa tgaaatttca gagtaaatac caattaatga attggtgtta taaagatatg
    33421 aactttccaa atcaacaaaa ataatattat catcgt
//
LOCUS       DARYMD010000022        32021 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYMD010000022 DARYMD010000000
VERSION     DARYMD010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32021
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(243..1292)
                     /locus_tag="TU818_000963"
     CDS             complement(243..1292)
                     /locus_tag="TU818_000963"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL0923792.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHRHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
     gene            complement(1816..2172)
                     /locus_tag="TU818_000964"
     CDS             complement(1816..2172)
                     /locus_tag="TU818_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923793.1"
                     /translation="MEDTYMTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGD
                     VEYLLTPKQEGYDDLVSFLESLGLNHFDATLYSDSMADQDYKKLLADFKGKTRSEVIS
                     AVLSELAKFYNDYSPF"
     gene            complement(2655..3003)
                     /gene="ssrA"
                     /locus_tag="TU818_000965"
     tmRNA           complement(2655..3003)
                     /gene="ssrA"
                     /locus_tag="TU818_000965"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            3094..3705
                     /locus_tag="TU818_000966"
     CDS             3094..3705
                     /locus_tag="TU818_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL0923794.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLEMPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            complement(3752..4546)
                     /locus_tag="TU818_000967"
     CDS             complement(3752..4546)
                     /locus_tag="TU818_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0923795.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(4556..5254)
                     /locus_tag="TU818_000968"
     CDS             complement(4556..5254)
                     /locus_tag="TU818_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923796.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            complement(5254..5625)
                     /locus_tag="TU818_000969"
     CDS             complement(5254..5625)
                     /locus_tag="TU818_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0923797.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELDREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            5867..8977
                     /locus_tag="TU818_000970"
     CDS             5867..8977
                     /locus_tag="TU818_000970"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL0923798.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGDL
                     DLDTLVQYLEGIAVIVPFSQSLRDLGLPFDYFIGIDEASDLSKIDSTERLIPLRTVRY
                     FDNAETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLREKQLWKEPYQFRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVESFLCSIPEKYQKTSFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVENHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            9057..10070
                     /gene="pfkA"
                     /locus_tag="TU818_000971"
     CDS             9057..10070
                     /gene="pfkA"
                     /locus_tag="TU818_000971"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL0923799.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
     gene            10132..11634
                     /gene="pyk"
                     /locus_tag="TU818_000972"
     CDS             10132..11634
                     /gene="pyk"
                     /locus_tag="TU818_000972"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL0923800.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            11763..12320
                     /gene="lepB"
                     /locus_tag="TU818_000973"
     CDS             11763..12320
                     /gene="lepB"
                     /locus_tag="TU818_000973"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL0923801.1"
                     /translation="MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNK
                     GDLITIKKNIEPKYKDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYL
                     ESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
                     DVSQIKGLVTFRVLPLKDFGFVEVE"
     gene            12497..14308
                     /gene="glmS"
                     /locus_tag="TU818_000974"
     CDS             12497..14308
                     /gene="glmS"
                     /locus_tag="TU818_000974"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL0923802.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIDRQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLEHLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQTLLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            14492..14827
                     /locus_tag="TU818_000975"
     CDS             14492..14827
                     /locus_tag="TU818_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL0923803.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTRGEEEPEEEGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            14934..15575
                     /locus_tag="TU818_000976"
     CDS             14934..15575
                     /locus_tag="TU818_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0923804.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            15585..16214
                     /locus_tag="TU818_000977"
     CDS             15585..16214
                     /locus_tag="TU818_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0923805.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLEPIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYALSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDSELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            16231..17067
                     /locus_tag="TU818_000978"
     CDS             16231..17067
                     /locus_tag="TU818_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0923806.1"
                     /translation="MTLKKTLLVALFAATATLLVACGASNKQTSSDAWDSYKQKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGINVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVATVQL
                     KS"
     gene            complement(17163..18401)
                     /locus_tag="TU818_000979"
     CDS             complement(17163..18401)
                     /locus_tag="TU818_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL0923807.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVTYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVTLLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSTQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPKDDNCEYVYKKLYKNEKIMLSQIPDYQELIAKTFTFIDRDGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSIAIKKHYHIKRIS"
     gene            complement(18504..19838)
                     /locus_tag="TU818_000980"
     CDS             complement(18504..19838)
                     /locus_tag="TU818_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL0923808.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGIYLTSRLSLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLANLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGISSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSALEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVIM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(19967..20053)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            20318..22609
                     /gene="pcrA"
                     /locus_tag="TU818_000981"
     CDS             20318..22609
                     /gene="pcrA"
                     /locus_tag="TU818_000981"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL0923809.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKYVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQGQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
     gene            23022..23267
                     /locus_tag="TU818_000982"
     CDS             23022..23267
                     /locus_tag="TU818_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL0923810.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            23315..23896
                     /gene="amaP"
                     /locus_tag="TU818_000983"
     CDS             23315..23896
                     /gene="amaP"
                     /locus_tag="TU818_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL0923811.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRVAVTEQLNGIKEGIETGL
                     TEFFGINRPVHFKVYVKDIADAKQKHSSKRRVE"
     gene            23906..24094
                     /locus_tag="TU818_000984"
     CDS             23906..24094
                     /locus_tag="TU818_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL0923812.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            24107..24646
                     /locus_tag="TU818_000985"
     CDS             24107..24646
                     /locus_tag="TU818_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0923813.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENIDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            24684..24881
                     /locus_tag="TU818_000986"
     CDS             24684..24881
                     /locus_tag="TU818_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL0923814.1"
                     /translation="MSEEKVNAKLEQAGGKIKEAFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            24891..25379
                     /locus_tag="TU818_000987"
     CDS             24891..25379
                     /locus_tag="TU818_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0923815.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            25535..26176
                     /locus_tag="TU818_000988"
     CDS             25535..26176
                     /locus_tag="TU818_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0923816.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FKVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(26293..26841)
                     /locus_tag="TU818_000989"
     CDS             complement(26293..26841)
                     /locus_tag="TU818_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL0923817.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLINDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQILKDFIYQFLTTIDGFQEIITKHYQIPYHYALEVYLASIESLISYWISHD
                     CQETTDDMTAIILKTVGFEKVI"
     gene            26964..27665
                     /locus_tag="TU818_000990"
     CDS             26964..27665
                     /locus_tag="TU818_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923818.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            27677..30316
                     /locus_tag="TU818_000991"
     CDS             27677..30316
                     /locus_tag="TU818_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL0923819.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILTSHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQIITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQILQDNGQERYEEMLNDLNRSLKDSKVKLEEQRTVLKASEDQL
                     ALLSGHALEQAQTQLKQGQEELAKKEASLLELAEKQRAAMIKPTYTSYSRSTLPGGEG
                     YQTYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGALAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLTAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPSYLVTTAKASPSAVKDVASQLLAMPAVQAVSQHSSIVATV
                     TGIVASLDQVMTLLVLLSVLLALVILYHLTNINIAERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSAVGILIGLWGGSYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            30392..30988
                     /locus_tag="TU818_000992"
     CDS             30392..30988
                     /locus_tag="TU818_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL0923820.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYHQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEREMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVNRAEQEWQFIQNEIQKGLG"
     gene            30998..31960
                     /locus_tag="TU818_000993"
     CDS             30998..31960
                     /locus_tag="TU818_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL0923821.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARKRLLSFFLAFAVAVSLFALFGFGLLSIGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILFNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVTQLTSQSRESLLLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLLQDLERFILLKVEFYRDYKEEQA"
BASE COUNT         9375 a         5744 c         7283 g         9619 t
ORIGIN      
        1 aatattcgta ttttatgttc aaaaaatgat ttttttatta agataaataa taacgtttgt
       61 tttttatgtc aggtatctag tttacttatc ttagaaaaga acaacaggca cattaatgtt
      121 taacaaaaca agagcttaaa gagttcatga caagctttaa ccaatgacag tgagctaata
      181 gggctattgt tagacgaaaa aacagaccaa taagcacttg gtctgttcct aatgatgact
      241 ggttagctca gtttctgcca tatgtccttg ccactggaaa gcgtaaataa gcctaatact
      301 tgagcgccaa tgttttctcc ttctattttc ttggcagaaa tggcgacatg tctatgagca
      361 ttaatgccga caaaatattt tttcatacca atagacgcat tagcatctga gtctgtgaca
      421 tagatggcct caaggtttcc ttcagcatta aaatcagctc cccacaagtt aatcacatgg
      481 ctaatgctaa cattggcgta ggtatgtgat aaagcaaggg ctcttccttc agtcagttct
      541 tgcttgataa tggtgctgat gtcatttagt cctttatttt ttaaatcatg acgagctgtc
      601 aagagcgttg tctgatctcc tctggtgaaa acagcatcga aaataccacc tcgtttgtcc
      661 ttgtcctgat aaggtcgatt gacatcagta gactgtgttt taaacacatt taagtagtaa
      721 ccattgataa acatgtctag aacaagatca ggcataaccc cgagttgacg tgctgataga
      781 tttggaaagg ctttatctct aaaataatta aaaagctgac tattggtttg actgtccttg
      841 gtatcgatag cagctttcaa atcaaatagc tcttggttgt taaaaatgat tttttgcttt
      901 tcagggtgtt tacttaaata ggcttcaatc tctgttttat tttgatcaaa ccaccaatgc
      961 agcatattac ctgccgttgc tgcgccacac aagagattat ccttcccatc gaaggccttg
     1021 gtgatatcgt accagccttg atgagcaaga tatggcgcat ggatcacatc ttcgttatta
     1081 tatcgaaact gctcgggtgt tagtggtgta acacctttgg tccatacaga agtgatctga
     1141 tgtggtactt ctttggcata agcttccgta gcattccttt ggtaatcgtc agcataagta
     1201 atgtttgaac tcgccaggct aaaaatagct atagcagtta agagaccagc tgataaggag
     1261 tgaggtttat ttggataagc tattgttttc atataaccct ttcttgttat ggtgatatta
     1321 tcattaaata atgttaatga catttatata ttatcacaat attttgttga gacaatgctt
     1381 ttgataagct ttatttatta gtaaatagtg atgagatagt agagatgctg gcagactgga
     1441 tctctataat ggatatttca gcttggttta tgttagcgtt acctatttta ccaatgatga
     1501 taccgtttgg tattgttggt gtcatgcctt agacatgagc tgttattatt gagaccacta
     1561 ataagagcta gtgtaggctt tgatgttatt gggattcttg cacaatctta gccaagctta
     1621 gtcagcaaat cagggcatta gctaggatag taaggacaat ggtgcagtta ttacttgatt
     1681 agctaggcgg acgatttagg agatggtctg gttactaagc agattgacaa agagaagcat
     1741 agctctatca agttaaaacc gctcggaagg ttgtctgagc agttttgatc tatgataact
     1801 tattgggtta tttcattaaa aaggggaata gtcgttataa aatttagcta attcagatag
     1861 aactgcagaa ataacttcac tacgagtttt acccttaaag tcagctagta gctttttgta
     1921 atcttgatca gccatagagt ccgaataaag agtggcatca aaatggttaa ggcctagact
     1981 ctccaagaat gacaccaaat catcgtatcc ttcttgctta ggcgtcaaaa gatattccac
     2041 gtcaccataa acatagtcat cagctttgct gatgtgggtt gaagctgtta ggcagactcc
     2101 tgccaaagct agggcagcca ttgtagaaac cataaatttc ttacaagctt gtgtcatata
     2161 agtgtcctcc atttccaacg gttcctttgt ccgtcgttat ttttgtgata ttttccttat
     2221 cacaatgtta gtttaactca aaatctgtca aaagtcaaat gtttttgtaa ttaaattaat
     2281 aaagtgtttt taaaaaatta aataaatgta gcttttggaa taattaaatt attgaaattt
     2341 tgtaaagaag cacaatatca taacagatga tatctataaa gcagcagtaa atgatgtcta
     2401 tataacaggc aatacagggc aattatccga aaaaatttga taatgtgctg tcaatgaagc
     2461 aagtagaaga agtattataa aaaaataaat ataagattag ctaaagagaa aattcaagct
     2521 gttcttaaag gattttttgg cctttttttt gctatcactt tcatagaaac ttacggtaac
     2581 ccacgaacag gacaaaaaga aaaaaccttg atttaacaag gttttagtaa gttatggtaa
     2641 cttacggtaa gtattgatgg agctggtggg agtcgaaccc acgtccaaac acctgctaac
     2701 ctatttgtct acaaccatag gttatgtctt actttaacag accaaggaca cataactcaa
     2761 gccatcagcc tgcgagtcta gggttctctt tttaggtgac tagacaatca cctaaacgta
     2821 gcttgctgtt ttgagacctc taataagaca caagcaatcc tatagaagtc acgccggctg
     2881 gtttttaggc agctaaagcg taagttgtgt tattttttgc agttatattt aactggcatt
     2941 tttacatctg ccgatgagtt gcaaaatagg cctcataatg cctgtcgaat ccgtaacaac
     3001 cccataaaaa ggcgtatgag atacttacgg atgctagtat agcaaaattt ttttaaaatg
     3061 gcaaaaaaat agcgcttatg gtatgatgaa gctatgagaa ataatgagtt gaagccttat
     3121 gtgatatggc aaaaagtgat taagctatta ggaagtctgg ctttagtcgg atcttttttg
     3181 ctagcctttt ggttttacag gcttggcatt ttaaatgaca gcaatgcact caaggatctt
     3241 gttcatagtc acaaggtttt tggccccctt gtttttgtcg gtgtgcaaat tgttcagatt
     3301 gtttttccta ttattccagg tggtatgaca actattgcag gctttttgat ttttggccct
     3361 ttgctgggtt ttctttataa ctatgttggt atcttcattg gtagtgtgat tctgttttta
     3421 cttgtgaaga cctatggtag gcgctttatt ttactgttta tagaggaaca gaccttttac
     3481 aagtatgaga gaaaattaga gatgccatat tatgagagat tgtttattct ctgtatgctt
     3541 tctccgattt caccagcaga tattatggtc atgattactg ggctgacaga gatgtcgttg
     3601 aagcgttttg tgaccattat tttaatcacg aagccactat caattattgg ctacagctat
     3661 ctttttatct ttggaaagga tttgatccta tggtttttcc attaaaaaag tctaggcatt
     3721 gcctgataag cagtggctag actttttgtt atcattggat attaagcttg tttttgatga
     3781 tgaagtgagt agcaacgtaa aggataatgc cttcaactag ttgctctatg tttaaaatag
     3841 atatggctgt atgatcaccg aaatagagta gcgagtctga gctatttggg ttgacggtga
     3901 aaaacgcatc atttaaataa gtcatgacga caataatgat aataactaaa atgaaatagg
     3961 cacaaaatgc catcaaacca cgacgatttg aaaatagctg accaattgag attgctagat
     4021 aaatcaatag tatacttgtt atggttgaca aaagcatgta gatgaggata gaagcatttt
     4081 cgactaagtt ttctggcttc ataattgtct ttagcacctt tagtagatag gtaaagtcaa
     4141 ctgttggcgc tattaaaata aagataccga ttaataggtt aatgccatta aaaatactgc
     4201 aaacaaagga cgctaacagc ttggacaaga taatctgatg tgctgttact ggtagtgtca
     4261 gtgttaagta tccctcgcgc ccaaagacat ttttgttaaa gcgattaatg atgattaata
     4321 gcgttgataa gaatgatccg gcaatcagag aaccaaacgt taatgagagt gtgagaggaa
     4381 ccattttgtt tgccagactt gttgttaaac caacctcgtc aggattgttt gtaagcgtat
     4441 tgatggtaaa agaaaggact atcgcgatag caatgacacc ggcattaagc gcaaaatacc
     4501 acttgccaat tgatctaaat tcgtatttta ataattttcc aaacatgcct acctcctaaa
     4561 ccttgtagat ctctctaaat aatgaatcaa tcgattgctg atgctgaact cgtaaatcat
     4621 cagcgtttcc agaaaggcag agcttaccat tttttaagaa aatagcttca tcaagtacag
     4681 gctcaatgtc tgagatgagg tgagtagaaa tgataacaga ggcttgctca gagtaattat
     4741 taataatggt tttaagaata taatctcttg ctgccgggtc aacccctccg ataggctcat
     4801 caaggatata gagctttgct ttgcggctca tcacgaggat aagctgtgcc ttttccttat
     4861 ttccctttga taggttttta aagcgctctt cagcatctaa gtctaaatcc ttcaggagac
     4921 tggtcgcttt atctctgtca aaatcggcat agaaatcacc aaaaaagtct agcatatcct
     4981 tgattttcat actttcatta agataggtcg tatctggtaa gtaagaaatg atttttttag
     5041 tttctacaga tggtctaaag ccgtcaataa caatgtctcc cttgtctggc tgtaaaagtc
     5101 cgttgattag cttaattagt gtagttttgc cgctaccatt tggtcctagt aagccgataa
     5161 tttttccaga agggattgtt atggttaaat catcaatagc taattgtttt ttgtaagatt
     5221 ttgagacgtg gtgcagctgt aatagttgtg ccattagttt gatccctcct ctaaaaaggt
     5281 acttaaaaca ggaatgattt ctgaacgttc aaaacctatt ttgatcatat tgctaataaa
     5341 ggacttgagc tcgttgatgg ccagctctcg tcttttgcgc gcgataagct cttggttatc
     5401 tgttacaaac cggccggcag ttcgttgcga gtaaactatg ccttcacgat ctaattcggt
     5461 aagtgctctt tgcatggtgt tgggattaac gccggcaatt tcagcatatt ctcggacagt
     5521 cggcagctga tctccacttt tgatctcttg gctgacaatt tgcagcatga tatgctgtgc
     5581 tatctgtgcg taaataggag atttctcatc aaatttccaa gacatactgt ctcctttctt
     5641 tctaaaatct gcgattaata tttgtactaa ttaaatgata caaaaaaacg attgacttgt
     5701 caagccttgt gtgtcatctc tagttacata ctggcttgca atgctagtgg gattcctgct
     5761 gatagtggtg cagtaaagac agatcactgc tattaaaagc ttaaaatctg ggcagtaaag
     5821 tctttttcat agtataatgg tagtaagaac gctaaaggag atgtccatgt ttgctcagtt
     5881 agatacaaaa acagtttatt cctttatgga tagtttgatt gatttagacc attattttaa
     5941 acaagccaaa cgattaggct atcaagccat agggattatg gatcaggata atctatatgg
     6001 ggcatatcat tttattaagg gctgtcaaag gcatgggctt cagccgattt taggtcttga
     6061 ggtggctatt acagttaaag agcaggctct tacgctgaag cttgttgcga aaaatgatac
     6121 aggctatcag cagctcttaa agctttcgac tgaaaaaatg tctggagacc tagacctaga
     6181 cacattggtg cagtatttag aagggatagc agttatcgtt ccttttagtc agagcttgcg
     6241 tgatttaggg cttccttttg attacttcat tggcattgat gaggcaagcg acttgtcaaa
     6301 gatagactct acagaaagac tgattccgct tagaacggta cgttattttg ataatgctga
     6361 gactgagact ctgcaaatgc tgcatgccat tcgtgataat attagcttag cagatacggc
     6421 tctagtagcc aaggatcagt ttttagcgcc ttgtcaggag atgacggcta ttttccagga
     6481 aaagtgccct gaggctttgg tgaatctcgt aaatctaaca gcttcgattg cttatcattt
     6541 tgatactgat ttaaagcttc cgagatttaa ccgcgataag ccagcaaaag aagagctaag
     6601 agaattgacc gagtctggtc taagagaaaa gcaattatgg aaggagcctt accaatttcg
     6661 tctggcagag gagctggcta ttatttcaga tatggggttt gatgattatt ttctcattgt
     6721 ctgggatttg ctgcgctttg gaaggagtag aggctattat atgggcatgg ggcgtggttc
     6781 agcagcaggc agtctagtgg cttattcgtt gcgcattact gggattgatc ctgtcaaaaa
     6841 caatttattg tttgaacgct ttttgaataa agaacgctac agcatgcctg atattgatat
     6901 tgatttgcct gatatttacc gctcagagtt tcttcattat gttcgagacc ggtatggtag
     6961 tgagcactca gctcagattg ttaccttttc gacttttggt cctaagcagg ctgttcgtga
     7021 tgtgttcaaa cgctttggtg tcccagaata cgagctaaca agcctaacta aaaaaattgg
     7081 gttcaaggat accctgagca ctgtttatga gaaaaatata gccttcagac agaccattaa
     7141 tagccgctta gagtttcaaa aggcatttga gatagctaag cgcattgaag gcaatccaag
     7201 acagacctct attcacgctg ctggtatcgt gatgagtgat gaccatctga ccaaccatat
     7261 tcccttaaaa aagggggagg atatgatggt gactcagtat gatgccagtg ctgttgaagc
     7321 taatggcttg ctgaaaatgg attttcttgg tctgagaaat ttgacgcttg tacagaaaat
     7381 gcaggaaaag gtggtcaacg attacggtct ttcaattgac attgaagcta ttaacctaga
     7441 ggatcctgaa acgatagcct tgtttgctag gggtgatacc aagggcattt ttcaatttga
     7501 acagcatggt gcgattagcc tgttaaaacg gatcaagccg actagctttg aggaaattgt
     7561 tgcgacaacc agcttaaata gaccgggagc aagtgattac acgcagaatt ttattaagcg
     7621 ccggcaggga caggaaaaca ttgatctaat agatccggtg attgctccga tattagagcc
     7681 aacctatggt atcatgcttt atcaggagca ggttatgcag attgctcaag tttatgcagg
     7741 ctttacactt ggaaaggccg atttgctacg gcgtgctatg tctaagaaaa acctcgttga
     7801 gatgcaaaga atgcaggagg attttctgac tggtgctaga gccttgggtc gctctgagga
     7861 gacagccaga ctattgtttg cacgtatgga aaaatttgca ggctacggct ttaaccgcag
     7921 ccatgccttt gcttatgctg ccctagcctt tcagctagcc tattttaaag cgcactatcc
     7981 tgaggtattt tttgatgtca tgatgaatta ttctagcagt gattacatca cagatgcgtt
     8041 agattttggc tttgaggccg cgcaggtgac gataaacacc attcccttca atgataagat
     8101 tgagcgtcat aagatttata tgggcttaaa aaacatcaag ggtcttccta gagaattttc
     8161 gtattggatc attgaaaata ggccctttac cagtgttgaa agctttttgt gcagcattcc
     8221 tgaaaaatac cagaaaacca gcttcttaga gccccttatc aaaataggcc tgtttgatgg
     8281 gtttgaaaaa aatcgccaaa aaatcattaa caacttagaa ggactgctaa cctttgtcaa
     8341 tgaattggga tcactttttg cggattcctc ctttagctgg gtagagactg aggattattc
     8401 agctgctgag aaatattact ttgagcagga tttgcttggt gttggcatga gcaagcaccc
     8461 cttgctagct gtcgctgaaa aaagcacagt agcagtcaca ccaatcacaa agttagtgaa
     8521 ggatacagaa gctactttgc tggttcaaat agatgcgatc agggttattc ggacaaaatc
     8581 aagcggacag cagatggcct ttttgagtgt tactgatacc aaacagaaat tagatgttac
     8641 cctttttcct gagcaatatg ctgtctataa gcaagaccta aaagaggggc atatttacta
     8701 tatcaatggc agggtaaaag aaagagataa ccgcttgcag ctagtctgtc accagcttcg
     8761 attagctcag agtcaaaggt attggctatt ggttgaaaac catcagcatg atgctgctat
     8821 ttctgacata ttaacagcct tttcagggga gactcctgtt attatccatt atcaagaagg
     8881 caaagaaacc ttagagttaa accatattag ggttgatgtt agtaaggatt tggaggaggc
     8941 tattagcccc tacgtgttga aaacggtttt tcgataaaaa tagcgaatta gtgaagtaat
     9001 ttgcaaacga atgtgctata ataaaaacgt taaattaatt aaaggagtac caaaaaatga
     9061 aacgtattgc tgttttaacc agtggtggtg acgcccctgg tatgaatgct gctattcgtg
     9121 cagttgttcg taaagcaatt tcagaaggaa tggaagtcta tggtattaac cgcggctatg
     9181 ctggtatggt tgatggtgat atctttccac taggctcaaa agaggttggt gataagattt
     9241 ctcgcggcgg gaccttcctt tattcagctc gctacccaga gtttgctcag cttgaggggc
     9301 aattggctgg tattgagcag ctaaaaaagc atggcattga aggggtagtt gtcattggtg
     9361 gtgatggttc ttaccatggt gcgatgcgct tgactgagca tggcttccct gcagtaggta
     9421 tcccagggac gattgataac gatattgctg gaacagacta tactatcgga tttgacactg
     9481 cggtcaatac tgcggtagag gctattgata agcttcgcga tacctcatca agtcatggac
     9541 ggacctttgt tgttgaagtg atgggacgca atgcaggtga tatcgcactt tgggcaggta
     9601 ttgcaagtgg agcagatcaa atcatcgttc ctgaagagga atttgacatt cataaagtgg
     9661 tctcaacaat taaagacgat tttgaaaata gaggaaaaaa tcaccatatt atcgttttag
     9721 ctgagggtgt tatgagtggc gaggcctttg cgcagcagct aaaagaagct ggagatgaaa
     9781 gtgaccttcg tgtgacaaac cttggtcata tccttcgcgg tggctctcca actgcgcgtg
     9841 atcgtgtgat tgcgtcatgg atgggagcgc acgctgttga gttgctcaag gaaggcaaag
     9901 gtggcttggc tgttggtatt cataatgaag agcttgttga aagtccgatt cttggaagtg
     9961 cagaggacgg tgccttgttc agccttactg atgagggtaa cattgttgtt aataacccgc
    10021 acaaggctcg cttagactat gctgctttga accgttcatt agcacaatag gataagtaag
    10081 atctggtaat ctttgttaat caactaaaaa ataagggagt ttcataataa aatgaataaa
    10141 cgtgtaaaaa ttgttgcaac acttggtcct gcggttgaaa ttcgcggtgg taaaaaatat
    10201 ggtgaggacg gctattgggc tggtcagttg gacgttgaac aatcagctaa aaagatcgct
    10261 gaattgattg aagcaggtgc taatgttttc cgctttaact tctcacatgg tgaccacaaa
    10321 gagcagggtg accgtatggc tactgttcgt cttgctgaaa agctggcacg tcaaaaggtt
    10381 ggtttccttt tggatacaaa aggaccagaa atgcgtacag aattgtttgc tgacgatgcc
    10441 aaagaatata gctatgtgac tggtgagcgt attcgtgttg cgacagcaca aggcattcaa
    10501 tcaactcgtg atatgattgc cttgaatgta gctggtgctc ttgatattta tgatgaggtt
    10561 gaggttggcc acactattct tattgacgat ggaaagcttg gcttaaaggt tatcgagaag
    10621 gacattgcaa agcgtgagtt catcgttgag gttgaaaatg atggcatcat tgcaaagcaa
    10681 aagggtgtta atatccctaa taccaagatt cctttcccag ccttagcaga acgtgataat
    10741 gctgatattc gttttggtct tgagcaaggt cttaacttta ttgctatttc atttgttcgt
    10801 actgccaagg acgttgaaga ggttcgtgag atttgtcgtg aaacaggcaa tgagcatgtt
    10861 caattatttg ctaaaatcga aaaccaacaa ggtattgata accttgatga aatcatcgaa
    10921 gctgcagatg gtatcatgat tgctcgtggt gatatgggga ttgaggtgcc atttgaaatg
    10981 gttccagtct tccaaaaaat gattatcacc aaggtaaatg cagcaggtaa agcagtcatc
    11041 accgcaacta acatgcttga aacaatgact gaaaaaccac gtgcaactcg ttcagaggta
    11101 tctgacgttt tcaacgcggt tattgacggt acagatgcga caatgctttc tggtgaatca
    11161 gcaaatggta aataccctgt tgaagcagtt cgtacaatgg ctacaattga taaaaatgca
    11221 caaactcttc ttaatgagta tggtcgttta gattcatctg ccttcccacg taccaataaa
    11281 actgacgtga ttgcttcagc tgttaaagat gcaacacact caatggatat caagcttgtt
    11341 gtgaccatca ctgaaacagg aaacacagct cgtgccattt ctaagttccg tcctgatgct
    11401 gacatcttgg ctgtgacctt tgatgaaaag gttcaacgtg ccttgatgat taactggggt
    11461 gtgattccag tgcttgctga aagaccagca tcaacagatg atatgtttga ggtagcagag
    11521 cgtgtagctc ttgagactgg tttggtgcaa tcaggagata atatcgttat tgttgcaggt
    11581 gtgccagttg gtacaggtgg tacaaataca atgcgtgttc gcactgtaaa ataatagctt
    11641 tccataagct ttagctattt tgctctatca gataatttaa ggcaaacaat gatacttaaa
    11701 aattgtttgc tttttttatt agtcatatca tgttataatg agactataga ctaggagtta
    11761 ttatggtaaa gcgagatttt ataagaaata tattgttgtt attgattctt attgtgggag
    11821 ctgtccttct tagaatattt gttttttcga cctatcgagt cacgtcagag gcttcaaatg
    11881 cctatttgaa taagggcgat ttaatcacca ttaagaaaaa tattgagcct aaatataagg
    11941 attttgtggt ttatacggtt gacaaaaagg attatgtgag ccgggttgta gcagtagcag
    12001 gtgatcgtgt tacctatatg gacgatattt tttacctgaa caatatggtt gaatcccaat
    12061 cctaccttga gagtatgaag gcaaagtatc tcaatcatgc ccctattggt acgctttata
    12121 cggaggattt tacgatttcg acggttactt ctggaaaata cgatagcatt cccaagggga
    12181 aatacctttt gctaaatgat aacagaaaaa accatcatga tagccgtcag tttggcttaa
    12241 ttgacgtgtc acaaattaag ggattagtaa catttagagt gcttcctttg aaagactttg
    12301 gatttgtaga ggtagagtag ctttaaggct gctctatttt gtttctcaaa atatgactat
    12361 accaattttc ttgttgacaa gatttttctg aagttatata ctctaaatat aacgttttag
    12421 tcggtttata tctgactata ccaattatat tgatcattaa agaaagtagt aagctagctt
    12481 actgaggtgt taagttatgt gtggaattgt tggagttgta ggtagtcgta atgcgactga
    12541 catcttgatg cagggattgg aaaaattaga gtatcgtggt tatgattcag ctggtatttt
    12601 tgtgtcagat ggcaggacgt ccaatttggt aaaatctgtt ggacgcattg cagatttacg
    12661 ctctaagatt ggcattgatg ttgttggaac gaccggtatt ggtcatacac gttgggcaac
    12721 gcatggtcaa gcaacagagg aaaatgctca ccctcatacc tctcagacag gtcgctttgt
    12781 tcttgttcat aatggtgtga ttgaaaatta cctccagatg aaggagcagt accttgctgg
    12841 acacacgttt aaaggacaaa cagacaccga aattgcagtt catttgattg gagcatttgt
    12901 tgaagaaggc tgttcagtct tagaggcttt taaaaaggct ttatcaatca ttgaaggctc
    12961 ctatgccttt gctttgattg atacagagga tatggatacg atctatgtcg ctaagaataa
    13021 atccccattg ctgattggcc ttggtgaggg ctataacatg gtttgttcag acgctatggc
    13081 catgattcgt gaaaccagcg aatttatgga aatccatgac aaggagctgg ttatcctgac
    13141 aaaggattca gcaagggtga cagattatgc tggcaatccg attgatcgtc agtcatatac
    13201 agcagagctt gatctttcag atattggcaa ggggacctat ccattttata tgctaaagga
    13261 aattgacgag cagccaacag tgatgcgtcg cttgatttca acctatgcag acgccaaggg
    13321 acagatgatg attgatccag ctatcataag gtctgtccaa gaggctgatc gtatctatat
    13381 tcttgcagct gggacctctt atcatgctgg ctttgcttct aagtcaatgc tggagcattt
    13441 gactgataca cctgttgaat taggggttgc ttctgagtgg ggctacaata tgccgctatt
    13501 gagcaaaaag ccaatgttta tcctcttgag ccagtccggt gagacagcag atagccgtca
    13561 ggttttggtc aaggcaaatg agatggggat tccaagccta acagtgacaa atgttcctgg
    13621 ctcaacccta tcacgtgaag caacctacac tatgctgctc catgcaggtc cagaaattgc
    13681 agttgcatca actaaagcct acacagcaca ggtcgctgca cttgcctttc tagctaaggc
    13741 agttggtgag gctaatggca agaaggaagc tattagcttt gatttggttc atgaattgtc
    13801 attggtcgct cagtctattg aggccacctt atctgacaag gagctgattg ctgagaaggt
    13861 gcagacctta ttggcaacaa cacgcaatgc gttttacatt ggtcgtggca atgattatta
    13921 tgttgctatg gaggctgcac taaaattaaa agaaatttca tacattcagt gtgaagggtt
    13981 tgcagctggt gagctaaagc atgggactat ttcactgatt gaggatggca cacctgttat
    14041 tggacttatt tcttcaagtg agctggttgc tgcacataca cgtggcaata tccaagaggt
    14101 ggctgcacgt ggcgctcatg tgttgacagt tgttgaggag ggcttagagc gtgagggaga
    14161 tgacattatt attaataagg tgcacccatt cttagcgccg attgctatgg ttattccgac
    14221 tcaattaatt gcttactatg cttccttgca gcgtggttta gatgtagata agcctcgtaa
    14281 tttagccaag gctgttacag ttgagtaata gttgcctgct taaaatgagg cagcagggtc
    14341 ctgaagccta tttgaaacga gcttgacatg atgttatgtc aggctcgttt tttagtgctt
    14401 gcctggtctt atgataacgt attcatcttg tcaaataagc atttctgaag taaaatatta
    14461 acgttaagac taagaagctt aggagagtaa gatgacgtta ccaaattgtt tacaatgcga
    14521 ttcagaatat gtttatgagg acgggcattt gctcatttgt ccgatgtgtt cctttgaatg
    14581 gacacgtggt gaggaggagc ctgaggagga ggggcttgtc gttttagata gtaatggaac
    14641 tagattagct gatggagaca ctgttacgat cattaaggac ctgaaggtca agggagcgcc
    14701 gaaggatctc aagcagggaa ctcgtgttaa gcatattcgt cttgttgaag gtgatcacaa
    14761 tattgattgt aagattgatg gctttggtgc aatgaagcta aaatcagaat tcgtcaagaa
    14821 gatttaataa caataagcaa ccagatgact ggttgtattt ttatagaaaa gtacttttca
    14881 atccatcaga aaatttggta taatggataa actatttata tctaggagac aacatgacgt
    14941 atattatgca ggttttaccc agcttgctgg atggtgcctt aatcacttta caggttttct
    15001 ttattgtaat tgtattatcc attcccttag gggctctttt agcttttttg atgagggttg
    15061 actttaagcc cttgcagtgg ctattgacgc tctatatttg ggtcatgagg ggaacaccct
    15121 tattgttaca gctcatcttt ttttattatg ttttgccaag tgtgggtgtt acctttgatc
    15181 gtatgccggc agcgattttg gcttttacct taaactatgc tgcttatttt gccgagattt
    15241 ttcgtggcgg gatagagact attccaaatg ggcaatatga ggctgcaaag gtgctgaagc
    15301 ttagtccggt acaaactgtt cgctatgtta tcttgcctca ggtgttcaag attgttttac
    15361 caagtgtttt caatgaggtg attaacttag ttaaggattc ttccttggta tatgtgttag
    15421 gagtagggga tttgctatta gcaagcaaga ctgcggcaaa tagagatgca accttagcac
    15481 cgatgtttat tgcaggtttg atttatttgc tcttaattgg tttggtcacc attttatcga
    15541 agcaggttga aaaaagattt aattattatc agtaaggggg tcatatgtta gaactgaaca
    15601 atatttcaaa gcgatttggt cacaagcaga tctttgatgg ctttcatttg accgttgaag
    15661 atggtgaggt tttatctttg gtagggccat ctggtggtgg caagactact ctgctccgaa
    15721 tgctggctgg cttagagcct attgattcgg gaaatattag ctataatggc gagtctgttc
    15781 ctattgatca tttagaaaaa agaagcctgc ttggttttgt ttttcaggat ttccaattgt
    15841 ttccacattt gacggtgctg gataatctca tcttgtctcc taccattacc atggctatgc
    15901 caaggcctga tgcaaagcaa aaggctatgg agctgctgga gcgcctaggt ctcaaagagc
    15961 atgcagctgc ttatccttat gcgctatctg gtgggcaaaa gcaaagagtt gccttggcta
    16021 gagcgatgat gattgaccca cagattgtag gctatgatga gccgacaagt gccttagact
    16081 ctgaattacg tcaggaggtt gagaaattga ttttgcaaaa tcgtgagatg ggcattaccc
    16141 agattgttgt cacccatgat ttgcagtttg ctcagaccat ttctgatcgt atcatcaaga
    16201 tcaatcctaa atagaagaag aggtagtgct atgacgttaa aaaagaccct tctagtagcc
    16261 ctatttgctg ctacagctac gcttttagta gcttgtggcg ctagtaataa acagactagc
    16321 tcagatgctt gggattccta caagcagaaa aagacgatta cgcttggctt tgataatact
    16381 tttgtgccaa tgggctataa ggacgagtca ggaaaaaata ccggctttga tattgagcta
    16441 gcaaaggctg tttttgacca atatggtatc aatgttaagt atcaagccat taactgggat
    16501 ctcaaagaaa ctgagttgaa caatggtaaa attgacctga tttggaatgg ctattctgtg
    16561 acaaaagagc gccaagctaa ggtggccttt acagagcctt atatgaaaaa tgagcaagtc
    16621 ttagtgacgc aaaaatcatc gcaaataagc tcatttgctg atatgaaaaa taagacctta
    16681 ggtgcccagt ctggctcatc tggctatgat gcctttacga gtcatcctaa ggtgctaaag
    16741 gatcttgtca agggaaatga cgctacccaa tatgaaacct ttacacaagc ctttatcgat
    16801 ttaaaaaaca agcgtattga tggccttttg attgataggg tttatgccaa ttattacctt
    16861 cagcaagaag gtgagctaga ccgctataac attatcgcga gtgagtttga aggtgaggat
    16921 tttgcagttg gtgtccgaaa agcggataaa accctacaaa aaaagattac acaagcctta
    16981 aaatcgcttt atcaggacgg taccttccaa aaaatctcta aaaaatggtt tggtgaagat
    17041 gtcgcaacag ttcagttgaa atcataagac gcaagcaaga cctaatcagc tcagaggggt
    17101 tgagactaga tacatttaaa agacttacct tctaaaggca agtcttttta tacggcttat
    17161 tattagctga tacgcttgat atgatagtgt tttttaattg ctatggagtt tgttattggt
    17221 gtgatttgat gatatatcag gtgccaagct tcgtgtcgtc tccagatact ggtatgctga
    17281 ttgccctgta gctgataggt gactagcttg gtgttgtggc tgatggattg catacaaaag
    17341 gcttcaagct gattggaaga agaacgctgc tgctctaaaa attgcttggc attgtaagct
    17401 tgtccatcgc gatcaataaa ggtaaaggtc ttggcaatga gctcttgata atctgggatt
    17461 tgacttagca tgattttctc gtttttgtag agctttttgt aaacatattc acagttgtca
    17521 tctttaggaa gctttgcagg ctcaacatga atatcaatat cataaacagc aaattgctca
    17581 ctcaagagct gttcgacctg ctcggttatg gcgtgacttt cataaacaga aaggtcaggg
    17641 tgcatctcaa ggacaatatc taaatagaca ttgcttccgt aagtgcggcc gcgctgtgat
    17701 ttgacagcaa tgattttggg aattttcaat atggcctttt catatgcttt gagctgcgtg
    17761 ctgtcaaagc catctgataa gctaaaggcg cttgccataa aaatatcaaa ggctgttttt
    17821 agaatgaaaa aggtaatgat aagggcagcc agcctatcaa taataggtag ctttaaggaa
    17881 gcggcgataa tagcaataga ggttccaata gaggtcacag catcagaaag attatcttta
    17941 gaggctgcaa ccaaggcact ggatcttacc ttttttgata acgctttatt aaaagcatat
    18001 actccaagca tcacaagggc tgaagcgatc ccaacaatag cacctaatgg atcgatagca
    18061 gactgcttac cactaatcat ctgttgaata gtttgcagga gaacctgaaa gccaacaatg
    18121 aacatgataa aggaggttat taagcttgaa aggtcttcga ttttccagtg gccaaagcgg
    18181 tgattggcgt ctgctggctg gctggccaga tgaagtccga tgagcagagt gacattacca
    18241 acgatatcag acaggttgtt gaagccatcg gcaatcaagg agctggcatt taaaagatag
    18301 ccagcaagaa gctttgtgat gctaagggcc aaataggtaa caatgctaac aatgggccct
    18361 ctttttgcta accgaaggtt ttctactgga ttgtttggca taaaaactcc tttgtaactg
    18421 atgctttcat tatatcataa aagctaagac aagctaaaag cctagagcta tcctaaatag
    18481 ggtattccag gcttttcgat agcttatttg gtgctttggc gcttaaaata tgcccttgtc
    18541 tcaaaaatga caacaggaga taaggctagt agggcgataa gatttggcag agccatcagg
    18601 ccattgacaa tatctgccag tatccaaatc aactccagct taagaaagcc accaagtcct
    18661 accatgataa caaagatcag gcgaaaatag ctgaggtgtg tcgtgccaaa taaaaagata
    18721 aagcagcgct caccataata gctccagccg agaatagtcg taaaagcaaa aagaacaagc
    18781 gacagggtca aggcataggt gcccatatgc ccaaagatag aagcaaaggc agactgtgtt
    18841 aagggtgctc cctctagtgc gctagtccac tgaccagtta ccaaaatggc cagaccagtc
    18901 agagtgcaga tgatgatcgt gtcaataaag gttccggtca tagaaatcag gccctgttct
    18961 actggctcct tggttttagc ggcagcagca gcgatcggag cagagcctag tcctgattcg
    19021 ttagaaaaaa ccccacgtgc aatacccttt tgaatggcgt ccttaaccaa gcttccggca
    19081 aagcccccta tagctgctgt aggggtaata gcggacttaa agataaggac aagcatagga
    19141 agaagcttag tatagtgaac agcaataacc gttaagcttg ctccaatata aaagatagcc
    19201 atgaaaggaa cgactgtttc agccaccttg gcaatagctt gaatgcctcc aaaaataatc
    19261 atggccacaa cagcagctag caagacactg attaatggcg aagagatccc aaggctatgg
    19321 tgtagggatg aggtaatcgc attgacctga gcaaatgtcc cgattccaaa caaagccact
    19381 aaaataccag agacagcaaa taagttggct agaggcctcc atttttgccc cataccattt
    19441 aaaatgtagt acataggtcc gcctgaaatc tgaccattag cgtccttagt acggtattta
    19501 atggctaaaa cgccctcgga atatttggtt gccataccaa agaaggcagc aacccacatc
    19561 caaaaaagtg ccccaggtcc accagacttt atagcggttg cgacaccaac aatattacca
    19621 gtaccaactg tagcagctag ggctgttgct agagcagcaa atgatgaaat atctccttgc
    19681 ccctcattct tagcaaaaat gagcctaaag gccttaggca acttgatgac ttggagaagg
    19741 ctaagtctgc tggtgaggta aatgccagta ccaagcagca gtagcaacaa gggtgctccc
    19801 caaaccaaat cgtctatcca ttttgcagca gctatcatgc ttaattcctc aactctctta
    19861 accaatgctg ccaaaagaaa aagccacccc tgcggatagc ctctgaagca tatgacaaaa
    19921 cagcaagcac aaaaaatgct aaggaagcat gatcatacgg cttgatattt tatcttctgt
    19981 ccttttgcct gagagattga gcagtcttgc cttgcccctt cggcgcctaa taggtctctc
    20041 cagaagcccg tccgtcaagc agtcccgtcc aacacctgaa cacctgagag tataactcct
    20101 tcggcgaaat ccattcttct cctgcatgac atcattcggt ttattaaatt atgtctatga
    20161 tacccaaaaa gcctagtgat gtcaacaagc aatttaactg atggctaact ccttgttttt
    20221 atggtaacat cattgtcctc ttttttcttt ttgactgaaa catgatataa tcgtaaggtt
    20281 aataaaagtc acttattaga cgatatgagg agaaagcatg aatcctttat tagatggaat
    20341 gaatgataaa caagcagagg cagttcaaac gactgagggc cccttgttaa ttatggctgg
    20401 tgccggttct gggaaaacga gggtattaac ccaccgcatt gcctacttga ttgatgaaaa
    20461 gtatgttaat ccctggaata ttttggcgat tacctttact aataaggctg cgcgtgagat
    20521 gcgagaaagg gcattggcct taagcccagc caccaaggat accttgattg cgacctttca
    20581 ctcaatgtgt gttcgtattt tacgccgtga ggcagatcat attggctaca atcggaattt
    20641 cacgattgtt gatccaggag aacagcggac cttaatgaag agaatagtaa aagctctaaa
    20701 tctggatcct aagaaatgga gcgagcggtc gattttagcc accatttcaa atgctaaaaa
    20761 tgatctctta gatgaaagag cctatgagct aggagcctct gatttgtata gccagacagt
    20821 tgcccgctgc tacaaggcct atcaggagga gctcagacga agtgaggcta tggattttga
    20881 tgatttgatt atgatgacct tacgcctatt tgatcaaaat cctgacgttc tagcctatta
    20941 tcagcagcgt tatcaatata tacatgtcga tgaataccaa gacacaaacc acgctcaata
    21001 tcagctagtg actcttttag cctcacgctt taaaaatatt tgtgttgtcg gtgatgcaga
    21061 ccagtccatt tatggctggc gtggtgctga tatgcaaaat attttagatt ttgaaaagga
    21121 ttaccctgat gcaagggtgg ttttgctgga agaaaattat cgctccacca agaaaatcct
    21181 tcaggcagct aacgaggtga ttcagcataa tcgtcatcgt cgtccgaaaa aattgtggac
    21241 tcaaaacgca gacggtgagc agattgttta ttatagggca aatgatgagc gtgacgaggc
    21301 tgtttttgtt gcctcaacca tcagcaatat gtgtctagag ctaggaaaga gctttaaaga
    21361 ctttgctgtt ttatatcgta ccaatgctca gtcccgtacg attgaagaag ccttgttaaa
    21421 atcaaatatt ccctacacga tggtcggagg aaccaaattc tacagcagaa aggaaattcg
    21481 tgatgtgatt gcctatttga ctgtggttgc taatccgtca gataatctct cctttgaacg
    21541 aattgtgaat gagcctaaac gaggggtagg gccaggaacc ctagataagc tccgccaatt
    21601 tgcttatggg caaggacagt cattgttaga ggccgcttca agccttgagc aatcaccgct
    21661 aaaaggaaag gctgcccaag ccatgctggc cttagcgagt ctcttaagtg atttgagagc
    21721 tgatttagac cagctgagca ttacagccct ggccgaggcc ttgctggaga aaaccggcta
    21781 tctggatatg ctgcgcgtcc aaaatacctt agaaagtcaa gctaggattg aaaatattga
    21841 agaattcctg tctgttacca aaagctttga tgacctatca gcacagcagc aggagcatga
    21901 agcaggtatt gatcgcttag gaagatttct caatgacctt gctttgattg ctgatagtga
    21961 tgatggcaat gcagaaaccg ctgaggtaac tttgatgact ctgcatgcag ctaaggggct
    22021 agaatttcct gttgtttttc tcataggtat ggaggaggga gtctttcctt tagcccgagc
    22081 agccgaggat caagatgagc tagaagaaga aaggcgacta gcctatgttg gcattaccag
    22141 agccgaggaa tgcttgtttt taacgaatgc caatacacgt accctatttg gtaaaagcag
    22201 ctataatcgc ccaacaaggt ttttaaaaga gatgtcagag aaccttttaa gcttccaagg
    22261 cttggcaaga cctgctcatg cttcctttgg tgtgacattt tcgcagcagg gtcaacgaca
    22321 atttggcaca ggaatgagtc tatcagaggc tatccagtcc agaaaatcaa tggcacagcc
    22381 tgccagagca gcctcaacat ctacaccgct gccctttgga ccgaatgcag ctacttcaaa
    22441 gcaagccgtt gattggcaga ttggtgatat tgcccatcat aaaaaatggg gtgctggaac
    22501 ggttttagag gtcaagggat ctggtaagac catggaatta accattagtt ttcctgatgt
    22561 cggattaaaa aaactccttg ccagcgttgc tcctattgaa aaaaaataaa aggtacagct
    22621 tatgggcaat ttgcatagtc acttggataa gggctttgca attgcggttt agttctgcga
    22681 tttaagaaaa gaagtaagca aggattttat cagttaacca cataccaagc ttttgatggc
    22741 cttgatgccg gagagagctt ggtatttttt tatttttaaa aaaatcacaa aaaatgattt
    22801 attctgagca taatccttgc aaattaaaat gagaagtgta taatggcaat ataaattaaa
    22861 taacaagtgg tcacttttgt taatagttgt tttaaggtat ttgtagcgct ttattgttaa
    22921 acataaatgt atcaaaaaaa taactagcaa ttttatattt aatttatgta gtcactttaa
    22981 agagtgaaca aagtagtttt attgaattga ggagatttat tatgggaatt atttggacat
    23041 taattgtggg tgcacttatc ggtgctattg ccggtgcgct tactaaaaaa ggcggatcaa
    23101 tgggctggat tgccaatatc gctgcaggac ttattggatc atacgttggt caagctttgt
    23161 ttggcagctg gggtctaaca ttagctggca tggcactttt cccatcaatc attggtgctg
    23221 ttatcgttgt tatcattact tcttttgtac taaataaatc aaactaaggg catttctatc
    23281 attatagaga tggttgagta ggaaagaggt ttttatgtcg aaatttttaa aaattagcta
    23341 tagtctcatt ggcttagtcc tattgacggt ctttggtggc gtgatagcca taactggaga
    23401 ttatattagg ctacctattg gctatcaatg gcttcactgg gatatgaatt ggcttcctaa
    23461 attcctaaat ccggccttat attactatta cttttgggca gctatcgctt tatttctaat
    23521 aacagtgctg atccttcttg tgattatctt ttatccacgc acctatactg agattcagct
    23581 ggctaaggat aaaggaaccc tgcttttgaa agggtctgct attgaaggct atgtagcagc
    23641 tgctattaaa gcagcagggc ttatgtcaag cccaagagtt accgctaagc tgtacaagcg
    23701 taaatttaag gttaatgtca gtggacaatt agcttctcgc gtagctgtca ctgagcagct
    23761 aaatggcatt aaagaaggaa ttgagactgg tttaacagaa ttctttggta ttaatcgacc
    23821 tgtccatttc aaggtttatg tcaaggatat tgctgatgct aagcaaaagc atagctctaa
    23881 gagacgtgta gaataggaga ttatcatggc attttatgaa cggtttaaat accctattat
    23941 tggtggtctg atagggctga tagctgctgt attactgatg acctttgggt tatttaaaac
    24001 actgctggca attattttca ttattttagg agtatatggc ggcctgtatg ccaaaaagac
    24061 aggtattatc gatcaattga tcaaacgtaa ctaaaggaga tttatcatga ctgaaactta
    24121 cattaaaaac acaactcata aagaaccaac ttcagctgtt cgtggcgaat tgacctatga
    24181 tgacaaggtc attgaaaaga tcgttggctt ggctcttgaa aacattgatg gcctactagg
    24241 tgttaatggt ggctttttgg ccaatctaaa agacaagctt gttaatagtg attctgttcg
    24301 tgatggggtt aatgttgagg ttggtaaaaa agaggttgct gttgatttag acattgtagc
    24361 agaataccaa aagcatgttc caaccatttt tgatgcgatt aaatctgtcg tagaaaatga
    24421 agtcaagaga atgacagatt tagaggtgat tgaggttaat gttaaggttg ttgacattaa
    24481 aaccaaggag caatttgaag ctgataaggt cagcctacag gataaggtga ctgaggtagc
    24541 tcgctcaacc tctgaattta caagcaagca ggtagacaat gttaaggcat ctgtaggtgc
    24601 aggtgtagaa aaggttcaag agcaaactga gccacgcgtt aagtaagcta ggctgtcaaa
    24661 cgatagaaat agaggaaatc ataatgtcag aagaaaaggt aaatgcaaaa ttggagcaag
    24721 caggcggtaa aatcaaagaa gcctttggaa aggtgactgg tgataaatcc ttagaaaccg
    24781 aaggtaaggt tgatcaagca gccagcaaaa tcaaagaagt agctgctgat gctaaggacg
    24841 ctgtcaaggg ctttgttaag ggccttaagc aagataaata aggagttgta atgaaagcaa
    24901 aggacataaa aagtacgttg acctacgatg ataaggtcat tgaaaaaatc gttggacatg
    24961 ctttagagaa ggtcagtggc ttattagcag tcaatggtgg ctttttctca aatatcaaaa
    25021 ataacctagt gaatagtgac tctgttcgtg atggggtgtc tgttgaggtt ggcagcaagg
    25081 aagtggctgt tgacttagat attgttgttg aatatggtaa ggatattcca gcaattgttg
    25141 agtctatcaa ggctattgtt tttcaaaatg tcgatagcat gacacatttg agggtcgttg
    25201 aagtaaatgt gaacgttgtt gatattagaa ccaaagaaga gcatgaggct gctagcgtca
    25261 ctgttcaaga caggctaaca gacgcggcct cagcaacctc tcaatttgta gctgagcaag
    25321 cagacaaggt aaaagaaact gtctctaaaa ccacagataa taacgagaca gtagaataaa
    25381 acacaacaac taaaactcct gttaatgaca tattgtgggc tggtgtgatg accagctctt
    25441 tttatcagtg cttgaacaat gttatgctat tgtattctct gtgaaaatgt gatttaatgg
    25501 gaatggtatc atttgttaaa aaggagtaat tatcatgact agtaataaga gagagattac
    25561 taattccaag tatcaaaaga ttgccatttc agttgctgaa aggattgcca atggcgaata
    25621 tgaagtggga gaaaagctaa agtctaggac aaccattgct tcgaccttta aagtttcgcc
    25681 tgaaactgct agaaagggtc tgaatatttt agctgatctg aagattttga ccttaaagca
    25741 tgggagtggc gccattgtct tgtctaagga aaaggctatt gattttctga accaatacga
    25801 atccacccat tctatcgctg tcatcaaaga aaatattcgc cataatattc gtgagcagga
    25861 aaaggcaatg gagcatttaa cagtgcttgt taatgagttt ctgatgcaaa gccaatcaat
    25921 cagcaagcaa tacccgctgg caccttacga aattatttgt agtcaggatt cagagcattt
    25981 tggccaatcc attggtgatt tgaacatttg gcatcaaacg ggagcgacga ttgtagctat
    26041 tgagcatgat ggccaattca ttgtttctcc cggtccttac gctgttatcg aaaaaggtga
    26101 tcatatttac tttgtcggta atgaggacgt gatttctaga atgaaaacct tttttaatgt
    26161 tagaaagggt ctgtaatcac aaaaaaacac agagctgctt taaggtgatg gtgatatcac
    26221 gatgaagtgt ctctgtgttt ttgtgttatc aggctaaggc ttctaagtag cttatagctc
    26281 tgattgaagc ccctagatta ctttttcaaa gccaacagtt ttcaggataa tagctgtcat
    26341 gtcatcggtt gtttcttgac agtcatgact aatccagtag ctaatcagac tttcaatact
    26401 ggctagataa acctcaagcg cgtagtgata agggatctga tagtgcttgg tgatgatttc
    26461 ttgaaagcca tcaatagtgg tcaaaaattg ataaataaaa tccttgagta tttgtgaaaa
    26521 attcaaataa ctggagttag ccatagcagc aataaaggga agattatcaa tgatataagc
    26581 gagggcttcc tttagaacga gtctagtatc tgtaaaaata tgagggtcat ttaggagctg
    26641 gtataaatcg tctaaggtgt catttatgag atgagtcatc atatcatgtt tatccctgta
    26701 atgcagataa aaggtgcctc tattgacacc agcttttttg gttaagtcag aaacggtaat
    26761 ggtctcaaag ctcttttctg tcaaaagact gacaagtgcc tgcttcaaat aggccttggt
    26821 tggtgtgtgt cttgttgtca tcgactcatc tccttaagtc aacaaatgct gcttatctgt
    26881 tcttgttaaa gtcttgagga cattatataa taaggctagt ataaaatcaa caaggtgttg
    26941 atataaagga ggtgacatga tcagtgtcct atattgaaat gaggtcctct tcaaagacct
    27001 accagattgg agaaacaact gttaaggcta atgatgaggt atcctttgag attgaaagag
    27061 gggagcttgt gatcatttta ggagcctctg gtgcaggcaa gtccacagtg cttaatattt
    27121 taggcggcat ggatagcaat gaccaaggtc aggtcataat agacggcaag gacatctcga
    27181 cctatagtaa aaaggcattg accagctacc gtcgttacga ggttggcttt gtttttcaat
    27241 tttacaatct ggtgccaaat ctgacagcaa aggaaaatgt tgagctggcg gctgatattg
    27301 tggcagatgc acttgatccg actactgtct taaatgaggt ggggctagga ggacgtttgg
    27361 agcatttccc agcacagcta tcaggaggtg agcagcaaag ggtgtctatt gctcgtgcct
    27421 tggctaaaaa tcctaagttg ttgctttgtg atgagccaac aggggcttta gattatcaaa
    27481 ccggcaagca aattttaaga ttgcttcaag atatggcgca cgacaagggc aggacagtta
    27541 ttgtggtgac gcataatact gctctagcgc ctattgctga tcgggtcatt tatatgcatg
    27601 acggtcgtgt gaccaagaca gtgcttaata agcagccgct tgatattgat aggataacgt
    27661 attgagaggt gcctagatga aacaaaaaac cttatggaag gatagttttc gagcaataaa
    27721 agctagtaag gggcgttttt tgtccttgct atttttaatg gctctaggct cctttgcctt
    27781 ggttggctta aaggtggctg gtcccaatat ggaaaaaact gctagtcact atctagagga
    27841 gcatcaggtt atggacctta gtatcctaac ctcgcatggc ttttctgata gagataagca
    27901 agaattagcc tctcttaaaa atgcaagact agagtatgcg agctttgttg atggtgcttt
    27961 tgatcaccag aggaaggcta ttaggcttta ttctatgcca caaagcctat ctcaggccag
    28021 cttggtcaag ggagattacc ctagcaaggc tagcgacatt ttgctatctg aagctttatc
    28081 aagccgctat cggcttgggc aaataatcac gataagccta aaaacaaagg gattgctaaa
    28141 gcatagatcc tatcgtgttg tcggctttgc tcattctcca gaaatatggt ccaaaacaaa
    28201 cttaggtgtt tcctcagcag gggatggtaa tctctatgcc tatgcctacc ttcaccctag
    28261 tgcctttcag caagggcaca atctcttacg cattcggtat gatgatttaa gagggttgaa
    28321 tgccttttca actcaataca atgaacgatt gctacaacac caagcagagc ttgatcagat
    28381 cttgcaggac aatggtcaag agcgttatga agaaatgctc aatgacctta atcgcagctt
    28441 gaaagatagt aaagttaagc tcgaagagca aaggactgtt cttaaggcaa gtgaagacca
    28501 gctggctttg ctaagtggtc atgccttaga gcaagcgcag actcagctaa agcaagggca
    28561 ggaagagtta gctaaaaaag aagcaagctt gctagagtta gctgaaaagc aaagggcagc
    28621 gatgatcaag ccaacctata ctagctatag tcgctcaacg ctgccaggtg gtgagggtta
    28681 tcaaacctat gccacctcaa cacagtccat atcgcatgtt ggaaatatct ttcctgttgt
    28741 tttgtatttg gttgcggcct tagttacttt tacaacaatg gctcgctatg ttgacgaaga
    28801 acgaacgaac tcaggcttac taaaggcaat aggctattct gattgggata ttaccaaaaa
    28861 atttctgcta tatggtgcct tagctgcctt gttgggcact ggattaggag ttttaggagg
    28921 gacttatttt ttatctcggc tcatctcagc tatcctaaca gatgcattga ctatcggctc
    28981 tactcagctt tatttttatt ggagctatag tgtggttgca gtgcttttag ccttgttatc
    29041 tgctgttttg acagcttata tggtggtgag acgtgagctt tttctcagac cctcacaact
    29101 gttgctgcct aagcctccta gtagcggggc aaggatttgg ctggagcatg tctcctttat
    29161 ctggcggcgt ttatccttta cctataaggt tacttttcga aatatctttc gatataagca
    29221 aagaatgctg atgacagtaa ttggagtagc aggttctgtt gcgctcttat tttccggctt
    29281 gggcattcaa tcctcacttg ctaatagcct aagctatcaa tttggcaagc tgacagccta
    29341 tgacatgctc gtggtagaag ctccaacagc agaagctcat gataggcagg agctggcaca
    29401 atatttgaag gcagatcaga ttgctagtaa gaaagagatt tattacgcta acttatcact
    29461 aaagataaaa gacttagaca acaagcaaac agtgtcgttg atttctagcg atcagagcac
    29521 tctatctccc tattttagct tgattggtgc tgctgaccga aaaaagctag accttccaag
    29581 tactggagtg cttatctcaa aaaagcttgc tgactattat caggctcatg caggagatca
    29641 gcttgagctt gaagctagta acggtaaacg ctatcagtta agagtgagtc aggttattga
    29701 catgactgtt ggtcattact tgttcatgtc taaatcttat tatcagcagg tatttcggga
    29761 tatggaggct tcaccatcct atttggtaac aacagcaaag gctagtccat ctgctgtaaa
    29821 ggacgtagct agtcagctct tagcaatgcc tgcggttcag gctgtgtcac aacacagtag
    29881 tattgttgct actgtgacag ggattgtggc gtctttggat caggttatga cgcttttagt
    29941 acttctatca gttctactag ccttggtcat tttgtatcat ttgaccaata tcaatattgc
    30001 tgagagggtt agggaattat caacgataag agtcttgggc ttttatgaca aggaggttac
    30061 cttatacatt taccgggaaa ccatgctttt gtctgctgtt ggtattttga tcggtctctg
    30121 gggtggcagc tatttgcacg cctatatcat gaaggtgatt gctaatgatt ctatgagctt
    30181 tggtaggaca gttgatgctt atgtttacct agtacctgtt ggggctattg tgcttttgtt
    30241 gattgtgctt ggctatatgg ttagctaccg gctaagaaag attgatatgc tagaggctct
    30301 aaagtctgtt gattagggta aaatagtact tgaaaatcgc ttaataatat gctagtatta
    30361 aaatactata atttaataga aggatacttt tatggaagcg atgatagctg cctatttggc
    30421 tgatcataga gaaaagatac cacttggtca ggttgttgat tgctttaagg ggaaggctgt
    30481 ttctcgtaag gctgaggctg gtgaatttgg tttgattaat ctgtctgata tgggacagct
    30541 aggaattgac tatcatcagg ttagagcctt tcatatggat agacgacaac tattgcgcta
    30601 tatcttagag gatggagatg tcttgattgc ctcaaagggg actgttcaga aggtttgtgt
    30661 ttttcataag caagaaaggg aaatggtagc gtcctctaat atcacagtgc tgcgtcctca
    30721 gagggttttg cgaggctatt atattaagtt ctttttggag tctgctattg gtcaagcctt
    30781 gttaaaggcg gcggatcatg gaaaggacgt gattaaccta tcgaccaagg ctttacttga
    30841 tatccctgta ccagtgattc ctttggttaa gcaggattat ttgattaatc aatatttgcg
    30901 aggcctgcat gactatcaac ggaaagtaaa cagagctgag caggagtggc agtttattca
    30961 aaatgaaatt caaaaaggct tgggctagag gtaaaatgtg agcttaattg aacgaacaat
    31021 aaaaatgcta ttagcaacga tggctgcaat ctttcttgcc tctcagctac agctgtctta
    31081 tgccatatca gcgggaatta ttgccctgtt aggtgtgcta gacactagaa aatctagctt
    31141 aattgttgct agaaagcgtc tgctgtcttt tttcttagcc tttgctgtgg cggttagtct
    31201 atttgcctta tttggctttg gtctgctttc cattggcttg tatctagcgc taaccattcc
    31261 tttgctttat cagctgaaaa tagaggcagg tcttgttcct atcactgtct tggtgactca
    31321 cctgatgtct gagcagcgta ttgatttgtc aattcttttt aatgagctgt tgctgttttt
    31381 gattgggacg ggtcttgccc ttcttgttaa cgggtatatg gggtctcagg agcatcgcct
    31441 acgcttgtac caccaaaaga tagaagatag cttaaaggct atcttgtacc gttttgaatc
    31501 ctttttgtta gaaggccaag gacaaaacga gggacagatg attaaggaat tagagcttag
    31561 cttagatgag gcgctaaagc tggtttatcg cgaaaggcac aataccctct tttatcatac
    31621 caattatcag gtgcattatt ttgagatgag acgtcatcaa aatagattgt tggcgcaaat
    31681 ggccttaaat gtcactcagc taacatctca aagcagagaa agtctcctgc tctcccatct
    31741 ttttcatgag acagctcgtc agctgagtga gaagaattct gctttgacat tgattgatga
    31801 tattgagcaa ttgcttgagg tctttaggca aagagagctg cctcagacta gagaggaatt
    31861 tgaaagacgg gcgattctgt ttcagctgtt gcaggatttg gagcgcttta ttctactgaa
    31921 ggtagaattt tatcgtgatt acaaggaaga gcaggcatag tagctgcttg ctgctgtgat
    31981 taagagtctg gaaaaatcat tttctaggct tttttgctat a
//
LOCUS       DARYMD010000023        31752 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYMD010000023 DARYMD010000000
VERSION     DARYMD010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31752
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..1435)
                     /locus_tag="TU818_000994"
     CDS             complement(<1..1435)
                     /locus_tag="TU818_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL0923822.1"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGAANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPN
                     ALNGTFDPQKGTYVDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVG
                     LFFIDVANWSHFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPRNATLVVGALSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVT
                     FMSQYMVFTWIAFGISTILGIVVYACYG"
     gene            complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TU818_000995"
     CDS             complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TU818_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL0923823.1"
                     /translation="MKNNKNNGFVKNSFIYILMIVIVVAGFQYYLRGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIVEVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTAL
                     ILPSDSVLKEMTSVADKNGTDITVKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGG
                     GARGAMSFGKNKARSQAKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARI
                     PAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKK
                     AERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRS
                     DVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVG
                     ADLENVLNEAALVAARRNKTKIDASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEA
                     GHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRV
                     AEEIIFNAQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKS
                     YSAQTAQMIDDEVRDLLNEARNKAADIINDHRETHKLIAEALLKYETLDAAQIKSIYE
                     TGKMPNDPENDEAEVHALSYDEIKDKMTEAKE"
     gene            complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TU818_000996"
     CDS             complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TU818_000996"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL0923824.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TU818_000997"
     CDS             complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TU818_000997"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL0923825.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     KLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLL
                     QAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTD
                     KGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            complement(5344..6630)
                     /locus_tag="TU818_000998"
     CDS             complement(5344..6630)
                     /locus_tag="TU818_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL0923826.1"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            complement(6772..7143)
                     /locus_tag="TU818_000999"
     CDS             complement(6772..7143)
                     /locus_tag="TU818_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL0923827.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            complement(7130..7402)
                     /locus_tag="TU818_001000"
     CDS             complement(7130..7402)
                     /locus_tag="TU818_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL0923828.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRISSDEEA"
     gene            complement(7433..8944)
                     /locus_tag="TU818_001001"
     CDS             complement(7433..8944)
                     /locus_tag="TU818_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL0923829.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISGFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCYTSFLLSGILV
                     LSHKALASWMGAQQLAPSIVITAMVLLIVPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIVAALCYRVLGWTVYLTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGDTV
                     AIRDLTSLGLPTLVFLLFSIYLLVFQLIDSLLVKNILVSSGLSEITAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTVLFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TU818_001002"
     CDS             complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TU818_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL0923830.1"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDNVVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNAKFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVYSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLEAYQCQLPLVSADAIVLHQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGVHRDYVTIQYQQSDRISLPVDQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIAVLSRFRSKKEQSESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTVDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            complement(12410..12979)
                     /locus_tag="TU818_001003"
     CDS             complement(12410..12979)
                     /locus_tag="TU818_001003"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL0923831.1"
                     /translation="MVKMIVGLGNPGSKHQQTKHNVGFMAVDRLVKDLDVSFTEDKTF
                     KALIGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TU818_001004"
     CDS             complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TU818_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL0923832.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     AIPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDRSEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(14337..14702)
                     /locus_tag="TU818_001005"
     CDS             complement(14337..14702)
                     /locus_tag="TU818_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0923833.1"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATP
                     DLENLVTLAAVLEVTLDELVTGKEPAIKVIKKTEKPMNVWEFLTEESKRPMRKGDLLM
                     LLLVVIVLLGVYFIVIHFS"
     gene            complement(14823..15020)
                     /locus_tag="TU818_001006"
     CDS             complement(14823..15020)
                     /locus_tag="TU818_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL0923834.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKKVLQP"
     gene            complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TU818_001007"
     CDS             complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TU818_001007"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL0923835.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKNFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TU818_001008"
     CDS             complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TU818_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL0923836.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            complement(17976..18749)
                     /locus_tag="TU818_001009"
     CDS             complement(17976..18749)
                     /locus_tag="TU818_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL0923837.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTPKEQELYFHNILDQGLSVRQIEQLVKTKHPPKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            complement(18869..20092)
                     /locus_tag="TU818_001010"
     CDS             complement(18869..20092)
                     /locus_tag="TU818_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL0923838.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            20302..20781
                     /gene="rlmH"
                     /locus_tag="TU818_001011"
     CDS             20302..20781
                     /gene="rlmH"
                     /locus_tag="TU818_001011"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL0923839.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            complement(21081..21154)
                     /locus_tag="TU818_001012"
     tRNA            complement(21081..21154)
                     /locus_tag="TU818_001012"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21118..21120),aa:Arg,seq:tct)
     gene            21435..21506
                     /locus_tag="TU818_001013"
     tRNA            21435..21506
                     /locus_tag="TU818_001013"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21468..21470,aa:Glu,seq:ttc)
     gene            21539..21612
                     /locus_tag="TU818_001014"
     tRNA            21539..21612
                     /locus_tag="TU818_001014"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21573..21575,aa:Asn,seq:gtt)
     gene            complement(21873..24458)
                     /locus_tag="TU818_001015"
     CDS             complement(21873..24458)
                     /locus_tag="TU818_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL0923840.1"
                     /translation="MTKPKAWSLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYSSLSLLFIQHYYFGYMVAIFIFLLFLVNLISL
                     DTWKRRLRACLSFTSVSILSALTSAFILIPAYLDLTAYGETLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMASF
                     YLQPLDLFWQGMHGPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIIFAFILLSC
                     LLTLPYLTMDQYSFLQPSLLILSLAFLAAYLILLLSMQKTSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDRLVKKTADSNDQFFRLEQLLPQTGND
                     SMKYSYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGIKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNIYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQVFNGRISGEAAENTSTTIVHYQVTVPNHRQLYLSLPNIS
                     FSNHNATAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLRQT
                     AKLKA"
     gene            complement(24581..26200)
                     /locus_tag="TU818_001016"
     CDS             complement(24581..26200)
                     /locus_tag="TU818_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0923841.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTVDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            complement(26280..27152)
                     /locus_tag="TU818_001017"
     CDS             complement(26280..27152)
                     /locus_tag="TU818_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0923842.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     misc_binding    27274..27513
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27569..28591
                     /gene="trpS"
                     /locus_tag="TU818_001018"
     CDS             27569..28591
                     /gene="trpS"
                     /locus_tag="TU818_001018"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL0923843.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYKMFVFLA
                     DQQALTDHAKESEMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANVVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKVA
                     MGIRYF"
     gene            28792..30273
                     /gene="guaB"
                     /locus_tag="TU818_001019"
     CDS             28792..30273
                     /gene="guaB"
                     /locus_tag="TU818_001019"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL0923844.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIRELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
     gene            30654..31046
                     /locus_tag="TU818_001020"
     CDS             30654..31046
                     /locus_tag="TU818_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0923845.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIALHINKNPKYKYRI
                     SLMWNTPMRDLCVGGSSLSPELQELLDR"
     gene            31121..31522
                     /locus_tag="TU818_001021"
     CDS             31121..31522
                     /locus_tag="TU818_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0923846.1"
                     /translation="MKTLLKLIVFIVGTLVLMLGMEVKHRMDTYDQIKQVELKNAHSK
                     EVIEMYEQELISMDPQALTDEGLIKSYTIDSDSLFINPMGGFSIHLIINDDPDIYLRV
                     GLGRYDMERNLEIDGIYRSEKLEKLLKGVER"
     gene            31519..>31752
                     /locus_tag="TU818_001022"
     CDS             31519..>31752
                     /locus_tag="TU818_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0923847.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYDQVKQVELKNAHSK
                     EAIDIYEKKLKRLDPQALTDEGLIKSYTIDSDST"
BASE COUNT         9884 a         6364 c         5841 g         9663 t
ORIGIN      
        1 agccatagca tgcatagact acaataccaa gtatagtgct gataccaaaa gcaatccacg
       61 taaataccat atactgactc ataaaggtta cacagatgat aatagctaaa attggcaata
      121 gaggcacaaa aggagtttta aactccccac gttgaggctc tccagcgttt tttcttagct
      181 taatgatagc aaaggacatg atgacaagat aagcgagagt acagatattg acaaactcag
      241 caagactggc tagggggaat attcctgcac aaatcataga taatgcacca acaactaggg
      301 ttgcatttct aggaattctt gttttttctg tgatttgaca aagggctctt ggtaaaagtc
      361 catctctact gatactgtaa accgttcttg ctaaggcata ggtcattgaa atacaaactg
      421 taattagagt taaaatggca acaattgaga cataatctgc tgcccaatat aacccaatac
      481 tccttaaagc aaaggcaact gcatcaggta catctaattt tgtatagtga acaatcccag
      541 ttaaaaccat tgtaacaata acatataaga tcgttacaat cgttaaggat aatacaatac
      601 ctcttggaat tgttttttgt ggttctttga cctcatctac tgtcatggaa atagactcaa
      661 agcccaagaa agcaaaaaac atgactgagg ctccagcgaa aatacctgac ttaccaccat
      721 aaatttggcc aaagccataa ggcgcaaaat gtgaccagtt ggctacatca ataaaaaata
      781 agcctacaat gacaaataaa gccagagctg aaaattttaa cagaactaaa aagctattga
      841 atcgcaatgc tgcctttgaa ttcatcaata caatagcagt cactaatagc atcactagca
      901 ctggaagtaa atccacatag gtcccctttt gaggatcaaa ggtaccattt aaagcattgg
      961 gcaattgtaa gccataatta gccagtaagc cttttaaata gctcccccag ccgacagcta
     1021 cacttgaaat tgctgttaaa aattccatga tgatatacca gcccacaatc caagctggaa
     1081 attcacctaa tgtcgcatag acatagctat aagcaccacc atttgctgga attcgtgaag
     1141 caaattctgc ataaaagagt gctaatatac taatagcaat agcagataga ataatagaaa
     1201 tcgtcagcgc tggtcctgca taattagcag ctcctatgcc tgtaatagtg aaaattcctg
     1261 ttcccaccat tgatcctagg cccaaaaaaa tcaaatccag catttttaag tgcctattca
     1321 tttcagtctt attaatagct tgcctttttt tacgaaagat tgtcatcttg tcactttcta
     1381 gtcttaaaat agttctactt agtttatcat agttcctgac aattgtaaat ttcactaaaa
     1441 tgaccccaat atagcctaag acctattaaa aaacgagcta ggaccaaacc cagctcatct
     1501 tatatatcaa taatgactaa ttatttattc tttagcttct gtcattttat ccttgatttc
     1561 atcataggat aaggcatgta cctctgcttc atcgttttct ggatcatttg gcattttacc
     1621 agtctcgtaa atggacttaa tttgagcagc atccaacgtt tcatacttaa gaagtgcttc
     1681 agcaatcagc ttatgagttt cacgatgatc attaataatg tcagcagcct tgttacgagc
     1741 ttcgtttaat aaatcacgaa cctcatcatc aatcatttga gctgtttggg cagaatatga
     1801 tttttcaggt gacaattgcc ctggcatcat agcatgattg ccttcatatt ggactggtcc
     1861 aagtttttca ctcataccat actctgtgac catagcccta gccatttgag tggcctgttc
     1921 aaagtcattt gaagcacctg ttgtctgagc attgaaaata atttcttctg caacacgacc
     1981 acccataagc cctgcaagct gctccttcag atcatcttta gataaaagca tttgatcttc
     2041 ctttggaagc gcaatcatat agccgcctgc tcggcctcga ggcacaattg ttaccttgtg
     2101 cacaacacga gcattggata agactaaacc aacaatagta tgacctgcct catggtaggc
     2161 aaccatttcg cgctctctct gtgaaatgct acgatccttc ttagaaggtc ctgcaataac
     2221 acgatcctct gcctcatcaa tatcactagc atcaatttta gttttatttc gacgcgctgc
     2281 aacaagggct gcttcgttta gaacattttc aaggtctgca ccgacaaaac ctggagtttg
     2341 ttgagcaaca accttcagat tgacatcctc agcaagtggc ttatttttag cgtggacgcg
     2401 taatatcgcc tcacgcccct taacatctgg tcgaccaaca agcaccttac ggtcaaaacg
     2461 acctggtctt aacaaggctg gatctaagac atcactacgg ttggttgcag caatgacaat
     2521 gatgctttca ttaccttcaa agccatccat ctcaataaga agctgattaa gggtttgctc
     2581 acgctcatcg ttaccaccac ccatgccggc accacgacga cgaccaacag cgtcaatttc
     2641 gtcaatgaaa ataatcgctc gctcagcctt tttagcatct tcaaataaag aacgcacacg
     2701 actggcacca acaccaacaa acatctcaac aaaatctgag cctgaaatgc taaagaatgg
     2761 tactcccgcc tctccagcaa cagcctttgc aagcaatgtt ttacctgttc ctggaggtcc
     2821 ctccaaaaga acaccagcag gaatgcgcgc accgagtgcc ttgtatttct taggattctt
     2881 tagaaaatca acaacctcta ccagttcttg tttttcttcc tcagcaccag ccacatctgt
     2941 aaatctaacc tttacatcac cctttgcttg tgatctagcc ttatttttac caaaactcat
     3001 ggcaccacga gcaccaccac cttgattcat gatcatcatc atgaaggctg caaaaatcac
     3061 aatcggcaga aagctcataa gaaaggtaat ccaagcccca cttgagcttt cttgttttac
     3121 agtaatgtct gttccatttt tatctgcgac agaagtcatt tcctttaata cagaatcaga
     3181 tggtaaaatt aaggccgtaa attctgttac ctcagtggct gcactattac ctaaaaatga
     3241 caagcctgtg tcaatagaca ccttttgagg cttttcatat tttcctttaa cctcaacaat
     3301 gctgccacta ggctgatagc taagtgattt aatatcacct gccttcaaat gcttaattaa
     3361 ttttgaatag ctaatttgct ggctttgtgt actagttcct cttaagtaat attgaaatcc
     3421 tgctacaaca ataacaatca tcaatatata tataaaagaa tttttgacaa atccattatt
     3481 tttattattt ttcatacaac aataattgac cttttcctat tttgaataga cttcctcttt
     3541 taaaacaccg acataaggga gatttctata attttctgcg taatctaatc cgaagcctac
     3601 aataaactca ttaggaacat tgtagcacac atagtctgcc tcaatgtcta ccacacgacc
     3661 ctctggcttg tcaaatagtg tgataatctt aacggaatta gccttacgat atttgaacat
     3721 gtcacgcaaa tatttgagtg ttcgaccagt atcaataata tcttcaacaa agatgacgtc
     3781 tcttccctca atattggtgt caacgtcttt taagatttta acctctccac tgctagttgt
     3841 tccaccatta tagctagaaa caaccataaa atcaatttca acgtgagtgt caatgtgctt
     3901 catcagctcg gccatgaatg gaacagaacc ctttaagaca ccgaccatca agggattttt
     3961 accatgataa tcctttgtca actgctcacc aagctccttg gtcctttgaa taatgtcatt
     4021 ttcagaataa agaatttttt gaatatcttg ctcaagcata ctgtcacctt ttttctaatt
     4081 tatcaatata cagtttagcc aacattatat catgtttaga cgcttttctc aaatatgttt
     4141 catcaccaac cagcacaaaa ataataactc cagcctgttc tcctacgatg gcattttgac
     4201 gctgctcact tgtaaacttt ccatcgatga ataaacgtct taattttttt gaaaattcac
     4261 caagaaaaag cctatctcct gcctgcctat gacgtaaagt aactggtgat aagctatata
     4321 aagggatagc tatatcatgt cccttatcag tcaaactacc tgagaaaaca aatcgatacc
     4381 ctctataatt tagggaatca ccgtatgata ccattttaaa ttctcgattt aaatcagtct
     4441 ttggaatgat ttttttaata gcaaaagact ctttttcaat gaggagacaa taagtatttt
     4501 taattggata aatcccctgc ttttgtcgtc tgatgatgtg taaaagatca tcaaattgtg
     4561 attttttaat ggctagctgt ggaaacgttt ctaaataatg ctgaagcaaa aaaaactgaa
     4621 cagcagctga ttgagctaaa aaacagttta atcgatgaaa ttcaagtccc ttggttaaat
     4681 catcaaaggc ctgaagcagc aggcgacttt ccgcagataa atcaatcaaa gattgagtag
     4741 cttgaggatt ttctcttttg aaatctggca ggtaatgatg acgaacacga ttgcgaaaat
     4801 aagccatgct gtcattagaa tgatcttcaa aatgaaaggg attaggcagt tctgcttttg
     4861 ataccgttaa aaacggtcgt atcaactgac cattagcaaa gggctgaacc tctctgatac
     4921 cagctaaatg acgcaatcga ctaccacgaa tcagtctcat caaaatagtc tcagcctgat
     4981 catcagcatg atgtgctgtg actaaagccg aataatgctc ctgctgcatg atctcttcaa
     5041 aaaattgata gcgaagatga cgcgcagcat tctcagaaaa agcgccctga aaataagcaa
     5101 catagatagg aatagcatgc tttttagccc aagacctcaa ataagcctct tcgtcatctg
     5161 attctggtct ttgcttgtga ttgacatgcg caatgccaat ccgaatttgc aattttgctt
     5221 gaaaagcatg caaaaagtgc agcaaattca tcgaatctac tccaccagat acagctatca
     5281 aaacagcctg atgagcgtca aaataggcct tcttttttat gatgttataa atgtgttgat
     5341 aagtcatttt aaaatcgaat aaacatcgtc agcaattgct gtgatgtcgt cataggaagc
     5401 cttatctgta aaaacggata agataaaggg attatcacca taaacaatgg caacatcatg
     5461 cttgtaatcg taggcgtctc caatcttgtg agccactggc acagaaatat tttttgaaat
     5521 gcgctgatca tcaaatgccg tctgtgacaa ataagaaata atctgacctt tttgataata
     5581 gatagcttcc atgagatttg ctgctgcatg agaagaaagc aagcgctttt ccatgtccca
     5641 atctactcca gctaaagccc taatctctga ttgaaaggct tgattatatt gattacatag
     5701 gtagtagcct aagatattag tagcaacatt gtcagactgc tgagccacag cctttaaaag
     5761 ctccatcaca ttatagtcct ttttgtcagc tgttttactg attttaccac tgccagttgg
     5821 atcgtaatca ccataaaaat gattgacctc atcaatgtat tttaagctct taccttcaga
     5881 taagctacct gacttcagtt ttttttgaac actgtacagg gttgctaatt tggaaatact
     5941 tgccgcatac atctgtttat cagcattgat acctgcactg gcctgcgtgt taagctgctt
     6001 tacaaaaata gaataattct ctttattata tttttgcaat agcatttcct gaaccttcaa
     6061 catgcgattg tcggtaggtg acaactcctt ttgattaacc cagcccttat gatcaatgaa
     6121 ataataggtc ccatgctctg tttgagccat cttactagca tgaacctttc tgccaggctc
     6181 actatctgat gcaattgtct taacacctaa aacatagggt tcagcatata tagtcatctt
     6241 tttttgagtc caaaaatcca aatccacagc tgtctgctca aacataatat cctcgtaaac
     6301 aatctgacga ctagcttcaa ggtaagtgtc atctgccagt ctaaagacag gaatagctgc
     6361 cttgtttagc aaaacatcct tgataacaat tctattgtct ggtgcgatca tcgtctttgg
     6421 cacactcaat tcgggatccc tataagcaac tgtctcctca aaaacattgg gattagtcgg
     6481 aatccgacta taataaagag tggagctaac aatatcctga cttaagtgat agcgtgtcgc
     6541 ttcagaaaac actgggattt tttctgtact aatgaccgtt aaaggagtca cgaaaaatgt
     6601 cattaacata gctgctaata attttttcac aatggctcct tcctatttta cttctgtgcg
     6661 atgatggtct ttcttcagct cttgattttc cttttctagc tctgctaatt tgtcatcaga
     6721 aaaggcaaga aaggtttcaa ttttttcgac aatattatcc atagtcaatt actattttgg
     6781 taataatcca ggagttggat aaataacctc tccttctctt gataagtaat atttagccct
     6841 agcatacttt ttgacaaaat catcattttt tagctgctca gctaactgct tttcagactt
     6901 agtctttttt tctaactcac gatactcttt ttccaacgta ataatctgct gaccttgttt
     6961 tttcagtgaa acataaccct taaccaagtt ataggttggc agaataaaca agaacatcat
     7021 actaaccaag atccaaccca taaaacggtt ccgtttttgg atttcctctt cctcaaaccg
     7081 ttttttgata ttttcttcgt tgatataatg gttattcaac tggacgatac taggcttctt
     7141 catcgctact tatccttgtt tcgctgataa tgtcatacat tttagcagcg tcctcttttt
     7201 tagtgctatc cttcatatca agcacacgaa cagtaagcaa cttattgcca aacctgattt
     7261 caacctgatc atttagtttt aaatcagttg agcttttcgc aaggatacca ttaaccttaa
     7321 tacgtccctt atctgcgact tctttggcca ctgatcgacg cttaatcaat cttgatacct
     7381 ttaaatattt atctaatctc atatcttttg cctcacaatc cctttcattc tatcattttt
     7441 ctttgacaaa tggtagaaaa gaccacaatt tctctttaaa gacacctagc tttttgcaag
     7501 ctattaaaaa agaggataaa ccaacagcag atgacaccaa aagactaatc agcgcaccaa
     7561 gtcgacctga taatggcaag caatactgac ttgtaagcac acacatgagc atgatcacta
     7621 aagcaagccc atatttagca ttcactatcg ctttaaaatc aatatcagcc agcacagcat
     7681 acaagagtaa aacgaccagc aaggggatta gggtggataa ggagcttcca acaatagcgt
     7741 aatagtaggt taatataggt gttaagccta attttaataa aaagccaaac agcaaaataa
     7801 gcaaagattg cttgatgtga tcctcaatga agcatttttg atgaaagaat tgaatcatgc
     7861 ttgatactgc tataatcatc aggtaaacca ctaaggccag ccagccctta ttgtcctcaa
     7921 ataaggctcg attcatcaga tggagaatac taataaaacc aacagtcagt gttaaactaa
     7981 aataaaagat aaactcaaag aaacattgac tttgctctct ataggactcc cttttaatat
     8041 gaaacaagac tgttaaattc ggtaaataag ctgtaaataa ggccgtcgaa aaaatgagac
     8101 caaattgcag caagggctgt cccctatcgt aaacaccctt agtcatttca gctgttatct
     8161 ctgataagcc tgagctaacc aaaatatttt tcaccaaaag agaatctatc aattgaaaaa
     8221 caagcaggta aattgaaaaa agtaaaaaaa ctaaggtcgg caagcccaga cttgttaaat
     8281 ctctaatagc aaccgtatct cctgataaaa agctttttaa tgaataagca ctatgacgct
     8341 tcaaataagc taaaataact aagctcgcta ctaaatttcc aaaagcagca acatttgctg
     8401 ttaaataaac cgtccaacca agcaccctgt agcatagtgc agcaacaatg attatagcaa
     8461 ctcttatgat ctgctcaaga acctgactca gagctgtagg agccatattc atatcagcct
     8521 gggctaagcc tctgtaaaag gatataaagg gtactattaa caaaaccatt gctgttataa
     8581 caattgatgg tgccaactgc tgtgctccca tccagctagc caatgcctta tgacttagca
     8641 ccaatattcc tgacaataag aagctggtat agcattgcaa cttaaataga gctgctagct
     8701 gtagctgctt ttttttctgg gccatactgg caatcacatt gggtaaagca gttagaccta
     8761 aggctgaaat aatacctagc aaaggataga tttgttggta agcataaaag cccctatccc
     8821 ctaccaaatt ttgataaggg atacggtaac tggctgctaa taattttgac ataaaaccac
     8881 taataacaat cagaagactt gattgcttag ttttatgagg aagcttttct agatttaatc
     8941 tcaccaagtg tctctccaaa aagtatcaat tcttctaaaa tgacatggtc tttctgacgt
     9001 ctaacatcaa agataatttc aattttaccc tgatgctcac taatccttgc ttttaagctt
     9061 gtttttgaca gagcctcaaa ataatcctgt gtcaaatagt attgaagcga agcaacctca
     9121 aacctaacca taacctgatg gtccctcttc tcgactaatt cagcaaaggc tgtatccaag
     9181 tagtatttca acaagccaat ctccagtaaa taggctacct gatcaggata gtcaccaaaa
     9241 cgatccatga tttcatcttg caaatcagaa taagctgctc tagagtcaat ctcacgaatg
     9301 cgcttataaa tgtcaatttt ttgacgctcg tctttgatat aatcactagg taaataagca
     9361 tcaatatgca gattaatctc tgcattacct ttttgtcgcg tcaatgctct tccttgcttg
     9421 cttgcaatag cctgctccag cagctgagaa tacatgtcaa aaccaactga gtcaataaaa
     9481 ccactttgtg aagcacccaa tatatttcct gctccccgaa tagataaatc tcgcatagca
     9541 attttaaagc cagatcccag ctctgtaaag cccttaatag cttctaacct tttttcggaa
     9601 acctctgtta gtaccttatc aggcttatac atgagataag cataggcaat acgattgctc
     9661 cttccaacac gacctcgaag ctgatacaaa gttgatagtc ccatatgatc agcattttca
     9721 ataaataagg tattgacatt agaaatatca acccctgtct caataatagt tgttgcaact
     9781 aaaacatcat aatcaccatt gataaaatcc atcaaggtat tctcaagctg aatgtcactc
     9841 atttgaccat ggacaaaacc aatagaagcc tctggaacca attcttgcag ctctgccacc
     9901 ttcttgtcaa cagtgtcaac cttattgtaa acataaaaga cttgaccacc acgatccatt
     9961 tctcgaataa tagcttccct aatcaagcca ggattatttt ctaaaacata agtctgaaca
    10021 ggatagcgat tcgtaggagg cgtctcaatc actgataaat cccgaatacc aagcatagac
    10081 atatgcaggg tacgaggaat aggcgttgca gtcagtgtaa ggacatcaac cttggtcttt
    10141 aattccttta gggtttcttt atgcttaaca ccaaaacgct gctcttcatc aatgacaatc
    10201 aagcctaaat ctgaaaaaat cacatccttt gacagcaacc tatgagtccc aataataata
    10261 tcaacctgac ccttttttag cctttctaga ctttcagatt gctctttttt actgcgaaag
    10321 cggcttaaaa cagcaatttc aaccggatag ttctcaaatc tttccctaaa attctcataa
    10381 tgctgctgtg ctaaaacggt tgttggtact aagatagcta cctgcttatg gtcaccgata
    10441 gccttaaaag cagctctcat agccacctca gtcttaccaa agccaacatc accaactagt
    10501 aaacgatcca taggtctgac actctccatg tcttttttaa cctcttttat ggacctaact
    10561 tgatcatcag tctcaacaaa ggcaaaatcc tcctcaaatg ctctttgtaa ctcatcatct
    10621 ggagaaaact gaaatccttt ttgctgactc cgctctgcat aaagcttcaa caggtcatct
    10681 gcaatatcct caacttgctt tttaaccctt tgctttgctt tttgaaaacg accatcgttt
    10741 agtttattaa tctttggctc tttaccatct gctgatacat attttgataa gctttcaagc
    10801 tgatcaacag gcaaagaaat tcgatctgac tgctgatact gaatggtgac ataatctcga
    10861 tgtacccctt gtatgttaat cgtttcaatg cctaaaaaac gaccaatccc atgcacactg
    10921 tggaccacat aatcaccctt agacaattca ttgtaatcct ttaagcgttc agcattactc
    10981 atattagtac gacgagcacg acgcttcagc ctcttatgat atatctcatg ctcagtaatt
    11041 aaaactaatt tttcatcagc aaagtaaaac ccacctgcta ggtgaccaat aatgatttgt
    11101 gcttgatgta atactattgc atcagcagaa acaaggggca attgacattg ataagcctca
    11161 agagattttg ccaaccgctc ataagcttga tgagattcaa cctgtaaaag gacagttgct
    11221 ccagattttt gataccgctt aatctcatca atgagcagtg gaaattgatt gaaaaattcc
    11281 tgcatggcat actgtgttaa gctatacacc ttatcaaatt taatattacc aagtcccttg
    11341 tgaaaatttg aaaagaaggt ggcaggctta tagtgtcgca gctcacgata attgtcagca
    11401 aaataatgga gaaatggaag tgactttcct tgctgtaaat catctgtcaa caaatgagca
    11461 agctctaagt caaatttagc atttctgtca actaactttt ggaaatcatc aaaaaatact
    11521 ggtgttccct taggaaggta atctagaatc gtccattcat tatcataaaa cagtgattga
    11581 aatttacgga tgtccttatg cttcaggcct tcttttgtta cagtgagcaa ctcctccaga
    11641 tagcctttat gttctgcctt agcaagttga agctgctttt caagattatg actagcccta
    11701 tcaaaatcct ccggctcaaa aatcatatca cttgcaggct tgatactggt gctatccttc
    11761 ttttggagag atttttgact ttctatatca aagctcctaa taccatcaat ctcatcacca
    11821 aaaaattcga tgcgaacagg taagtcctgt gttacctcgt aaacatctaa aatatcacct
    11881 cgtctgctaa attcaccagg actaaggacc tgagccaccc tttgataacc aattttgaca
    11941 agcttcttga caacgttgtc aagatcagtg tcaactccta ctgctaagtc aatctgcccc
    12001 tgctgaaaag tcttaggact tggaagtagg attctgagtc ctgctaagct aatgaccaat
    12061 attcctcttg cttctggatt tgataaaaaa gctagtgcct ctattctcga gattgtttta
    12121 tccatagagg agaaaataaa ctcagccgca gcagtatcat ctgcaaaaaa ttgaaaaata
    12181 gagccctcat caagcaaggc tgacaaatca ccagctaatt tttccatgtc attttgagtt
    12241 gatgtcacca cgaccagctt cccttgaaag ctaagatagg ctgaggcaat ggctgctgct
    12301 ttacttgagc ctgacaagcc catgactaat tgccgtttta agcttgttac atcacattgc
    12361 caggtctgga ttgacttgtt ttgattaaat aattctaaaa tatccataac tacccattaa
    12421 attgctgcat tgttttctca atgctttttt cctgtaaata atagttgatt gctttgtcaa
    12481 ccttatcaag tgctatattg attgttatca tatcatctgt atcaaatttt cctagaacat
    12541 gattaataac actcattcca tgacttggtc ttccaatacc aattttaacc ctatcaaatt
    12601 cctgtgtacc gatatgagca ataatggatt ttataccatt atgtccccct gcagagcctt
    12661 tttgacgcaa acgaatttta ccaactgcca tatctaaatc atcatagatg accattaaat
    12721 ctttagttga aatattgtaa taggtcaata aagccctaac agcaagacca ctattattca
    12781 taaaggtagt tggcttaaca aaataaatct tttcttgatt gataaaagta ctcccaataa
    12841 gggctttgaa ggttttatct tctgtaaagc taacgtcaag atccttgaca agtctgtcaa
    12901 ctgccataaa accaacatta tgctttgttt gctgatgttt tgagcctgga tttcctaatc
    12961 ctacaatcat ttttaccata ctaatacacc agagaaacga ggtatgatag cagcctgttg
    13021 accattctta aagctttatc agcctcttcc cctctatttt ttgtcctttc taagcttttg
    13081 ataggcacca aaagggctgg aatactatcc caaccctaga acacaatatt gttaccacta
    13141 aacattgaat ctaaattcca taatatcgcc atcctgaacg atatattcct ttccttcctc
    13201 acgcagacga cctgcctctt taacagcctt ttctgagcca tacttaatca aatcatcata
    13261 gctcatcgtc accgcacgaa taaaaccgcg ctcaaaatct gagtgaatga taccagctgc
    13321 ttgtggtgcc ttaataccgc gcttgaaggt ccatgcacgc acttcctttt caccagctgt
    13381 aaagtaggtg ccaagtccaa gtaaatgata ggctgcacgt gtcagcttgt caacgccaga
    13441 ttctgtcaga ccgatagctt ctaaaaattc actcctgtct tcatcatcta actctgaaat
    13501 ctcttcttct gcacgagctg aaatcacaac aacctctgca ttttcagttg ctgcaaagtc
    13561 acgaatctgc ttcacataat caatagcgtc tggaattgct accttatcct catcaacgtt
    13621 tgccacataa agcactggct tagtcgttaa taaaaataac tgcctaacaa ttttttgctc
    13681 atcatctgta aagctaatgg tacgagcaga tttgccttct tcaagcactg gcttaatttt
    13741 ttcaaggaca gcaaattctg ctacagaatc cttgtccttt tgtgtacggg ccattttttc
    13801 gacacgcgca tagcgtttat tgattgattc taagtcagcc aaaattaatt caaggttaat
    13861 cgtatcaata tctgccaaag gatccacaaa ggcatcctca cgcccctgct cacgcatgac
    13921 attttcatca tcaaaggcac gaaccacatg aacaatagca tcaacctcgc ggatattggc
    13981 taagaactta tttccaagtc cttctccttt tgaagctccc tttacaatac ctgcgatatc
    14041 tgtaaattca aaggttgtag gtactgtttt tttaggcgtg ataagctctg tcaacttctg
    14101 taaacgctca tctggaacct ctaccatacc aacattagga tcaattgtcg caaaaggata
    14161 attagcagcc tctgcccctg cttttgtaat tgcgttaaat aaggttgatt tcccaacgtt
    14221 tggcaaacca acgatgcctg ctgttaaagc catatttttt tcggtctccg ttacattttt
    14281 tcaatcctta tcattatagc aaaaaaaaga agaaaaagct tgcctagtaa tgatctttaa
    14341 ctaaaatgga tcacaataaa atacacacct aacaaaacga tcacaaccaa taatagcata
    14401 agaagatcgc ctttacgcat tggccgctta gattcctcag ttaaaaattc ccatacgttc
    14461 attggctttt cagttttctt aataaccttg attgcaggtt cttttccagt caccaattca
    14521 tctaaagtta cctctaaaac agctgccaat gtaactaaat tttccaaatc cggtgtcgca
    14581 tctccatttt cccactttga aatagcctga cgggagatga aaagcttctc agctaaggca
    14641 tcctgagaca actgcttttc aagccgatac ttctttaatt gttctgcaaa tttagtcatc
    14701 attaatgacc gcctttcctt tttgatagct ttacaataac tcttttttaa aaggcaagct
    14761 agcaattttt aacgcaataa tgagttgcga aggtagttaa aaaccttatg acaatagagc
    14821 ttctatggtt gcagaacctt cttcatttta cgctcaaaat catgacgact tagcatgata
    14881 acatgattac agttagtgca ttgcagctta atatctgctc ctactcttgt gattttccat
    14941 tgatttgcct tttttcctgt ttctttaatg acacaggcat ggggcttttt catttcaatt
    15001 aaggatccaa cttgatacat cactttatca ctcactcatc tcttatattt attatttatc
    15061 ataacaaaaa aagcccccaa aagggagcgt ttttcgctta gtttgtacga actggtgtga
    15121 ttaattgaat aaagctctct tcatcatctc ccggtgttaa ggtgaaagga cgaacaggcg
    15181 ataggaagtg aatcttaacc gtctcacttt taatggcttt taaggcttca atcagatagg
    15241 ttgggttaaa gctaatggtt aaatcattcc ctgcttgact caccacgtcc agatcctcgt
    15301 taaccttacc aacctctgga gagttaacat gagctgaaat gcgatttgct tcaatttcaa
    15361 gcttaacagt accattttgc gtagcgtttg aaatcaagaa agcacgctcc atagcatgtc
    15421 gtaaggattg tgtgttaaaa acagcctctg tctcaaactg cttcatcagc aaacgatcag
    15481 tatcagggta attaccttct aacagacggg tgtaaaaaga aatgtagtca cttctaaata
    15541 gcatttgact agcagaaaag aacacttcaa cggtttctat atcatctgta aagacagctg
    15601 aaaattctct caaggattta cttggaataa ccacatcaaa atcagctgag gttttctcca
    15661 gagtaatcaa gcgctggctc atacgatgtg aatctgttgc caccgcttta aagttcttat
    15721 gctgacttag ggtgatgtgt acgcctgtca aaataggacg actttcctgc atactagcag
    15781 caaaggctgt ctcagcaatg atagatttta agagtcttgt atttaaaatt aaaggatttt
    15841 cagttgatac ctcttgaaga cgtgggtatt gagaaacatc cttccccttt aaggtgattt
    15901 cagatttccc actggttagc accacctgat gctgttcaat ttccttaaat tctaagctaa
    15961 catctggaag acttgagata atattgataa aaaagctggc ttctaaaaga acagcccctg
    16021 ttgaggttat caacaagcct gcgttttcat tgctaacagg aatggtattt tcaatagaga
    16081 tttgaccatt agagccagtc agggtaatgt ctgatggatt aacctcaatc ttgatggttg
    16141 ataagatcgg tatagcattt ttactgctga tagccctttt agtggctgtt aaagcttgaa
    16201 tgaaaagggc tctattgata gaaaattgaa tcatggtaac tcctttgtta tataagtatt
    16261 atagctagta gtagtagtag gtcttgttaa aatagtggat aagtctcctt gtactagtcg
    16321 ttactagtta aaacgcttgt gcacaagctg tggataaatt ttcctttttg ctaaaggtta
    16381 tccacattgc ttatttgatt ttgttcttga tggtttcaat ttcaattctg aggctctcgt
    16441 cttgtccaat catgttttta attttgttat aagcatgaag cacagttgaa tgatcacgtc
    16501 ctccaaattc tttaccgatc tttggcagac tgttatcggt catctcacga gctaaaaaca
    16561 tagcaacctg tctagcaagc acgatatcct gtgtgcgttt ggtcgccttg atttccttaa
    16621 ccgtaacccc ataaaatttt ccaacctgag cttggatttc ttcaattgga atgacagtca
    16681 tcttaggacc gtcttgcttt ctagctcgaa tagcttctgc tgctatgtct actgtaattg
    16741 tatcaatttg tttaaaatta gccacaagac taatatcctt caaagcccct tccaggtctc
    16801 tgacattaga gtcaaattga ccggccaaat attcgatggt gtcctgagga aagatgaaat
    16861 tatattcttg aattttattg gtcaaaatag caacacgtgt ctcaaaatca ggcggtgtga
    16921 tattaactgt tagtccccac ttaaatcgag ttactaggcg atcttctagg tcattgaggt
    16981 gatcaggggt tcggtcactt gttaaaacaa tttgcttgtt attgttatgt agagcattga
    17041 aggtgttaaa gaactcctct tgtgtaccag acaaggtttt tttagctagg gattgaatgt
    17101 catcaattag gaggagatca agattgcgaa atttctcctt tagctcgtcc atagtatcta
    17161 gacgaatatg aacaacaaat tcattaataa aattttcagc cgtaatgtat ttaatcctag
    17221 catttggatt ttccagtaaa actgaatttc caatagcatt taaaagatgg gtcttaccaa
    17281 gacctggacc tccccagata aataaaggat tataggttgt tcctggtgta ttagctaccg
    17341 ctattgatgc agcaacagcc cacctatttt catcaccttg gataaagttg tcaaagctgt
    17401 atttagggtt tagatcggac tgtactgctg gtaattgctg gaaggcttgt tcagtatatc
    17461 cttgctgtcc ctgatgctgt tgctcaatca tcaagtcatc ctcatagaca tagtctacag
    17521 caatttgagc attgtaaact tcaaatcctg ctgttaggat aacgtctttg agattttttt
    17581 cccaaaacaa ttccttcatc tgatctaaaa aaattgttgc gacatgattg tctaccttga
    17641 tcaaacgagc atcatgaaca aaaaattcat aagttgcctg ctttaactgg ctttgagcta
    17701 gctctaagac cctattccaa aaaatttgtt cattttcagt catacgagat tccttcttgt
    17761 ggataattct agaaccattc tatcataaat aaagatagtt ttccacaaag gatcaaggat
    17821 tattttagac ttacccacaa gctgtggaga taaaatacac aatgtgtaag atagttttcc
    17881 acaacttgtg gaaaaaagag aaagccttgt gataaaaggt tttagcccca tttctcttgt
    17941 ggaaaactga ataaaaaaaa cagacaatca acaagctaaa gcaacttgtt gataattctg
    18001 ttcaattctt cttggtttga aaatgacagt tgcagctgcc cactgtcatt tttttggaga
    18061 gacaatgcca caggtaatcc taatgatttt gagagctctt tttctaaaga cttcacaaaa
    18121 atggttttat gtttgtttct tttttttggg ggatgcttag tctttaccag ctgttcgatt
    18181 tgcctaacgc ttaagccttg atccagaatg ttgtgaaaat aaagctcctg ctcttttggt
    18241 gttgacaagg ataataaagc tcttgcatgg ccggcgctaa tggtaccgtc ctcaatcgct
    18301 tgtctaataa cgtctggtaa ttgcagcagt ctgatggtgt tgctgatata agggcgtgat
    18361 tttcccatgt atgtcgcgat gtcctcatgg gtcatcttat ttttatcaat aagtaattga
    18421 taggccttag cctcttcaat agcatttaaa tttgagcgct gtaggttttc tacgatggcc
    18481 tgctgcatgc tctcaagagt agagatttcc ttaacaattg ctggaatctt ttgaagtcct
    18541 gccagcttgg ctgctttaaa gcgtcgttct ccagcgacta attcatagcc aaatacatca
    18601 gattttctga caatgattgg ttgaatcaaa ccattagcct gaatggaatg tgccagctct
    18661 tcaagctctt tttgattaaa ttgaagacgt ggttgataag gatttgccac aatatcctcg
    18721 ataggaatgt gcattaggat ttctgtcata taagcctctc aaaagggaaa tagtggtagc
    18781 ttaacggtta ttagagatac atacgggata aaagagcaag agcccgcgac catcgtctcg
    18841 gactcaatct cacggggata cccaatgttt actgcttttt agttagatcc ttagttgttt
    18901 ttgttaattt gatgtcaact ttcttcttag cagttcctct gtagaaggtt accttaatgg
    18961 tgtcgttaat ctcatgacta tataagacac tttgtaggtc actaattgag ctgacttctt
    19021 taccgtcaac ctcagtaatg acatcatact gctccaattt accaagagca ggcatgccat
    19081 cttgagtaga ggctacgaca acaccgctgg taacgcttgt tggaatattc aattgaatca
    19141 atgcattggt tgatagatta cttaagttta ccattgtaat gcctaaggct ggtctgataa
    19201 cagctccgtt agactctagt tggttaataa tggtgacaac atcgcttgat ggaatagcaa
    19261 agccaattcc ctcaatggct ccgccgctac cagtaggtgt tgaggatatt ttacttgagt
    19321 tgataccaat aacctggcct tcaatattga tgagtggtcc acctgaatta cctggattga
    19381 tagcagcatc agtttggata gcatttgttg agatggtctc gcctgcctca tttcttgaag
    19441 tgactgtacg gcttagactt gaaacaatcc cttctgtcac tgagttggca tattttgttc
    19501 caagaggact accaattgca atggctacct ctccaacatt aattttggtt gaatctgcaa
    19561 atttggctat tgttttgatt ttatcagcag caactttgac aacagctagg tcagaataag
    19621 tgtctgcacc aactagttct ccaacgatct tagagccgtc tgctgttaaa atttcaattc
    19681 gttgagctcc ctcaataaca tgattgttgg ttacaagata agcagtatta ccttcttttt
    19741 tgtagacaac acccgaacct tcactgtgta tgcttagctc gtcctctttt tgtactgctg
    19801 aggtatcatt ttcttctccg aaaagattga tgtaaggatt tgaaatggca ggcgaagcag
    19861 ccttttgata gttaataaca gacactacag catcttgaac caccttaaca gcctttgttg
    19921 tatcagttgt attattaaag ctgacgttgc ttgttgtcgt tgctcccttt gcatttgaag
    19981 atgttagaga attctgacta aatccattaa caactaaggc agctaataag ccccctaaaa
    20041 atccaatggc taaaacccat aagggcttca atatattttt tgattttaac acaaaatcac
    20101 ctccgaatgg ttttcacata ggatataaaa cctcacttaa ttatacctta aaaccataaa
    20161 aaagaaaagt aatccacaac ttgtggaaaa cttttcagga ctatactaaa aaggctgtag
    20221 aaaagggttt atataaagaa aataagaaat caacatgtgg ataagttgtg taaaaagagt
    20281 tgattatggt acaataagga tatgaaaata aagcttattt gtgtcggaaa attaaaagaa
    20341 gcgtatttaa gagatgggat tgcagaatac caaaaaagac tgtctcgctt ttgccaatgt
    20401 gatatcattg aattagcaga tgaaaaaaca cctgataagg ctagccatgc tgaaaaacag
    20461 cagattatgg ctaaggaggc tgacaggatc aagaaaaagc ttggtcagcg tgattttgta
    20521 attgctttgg caatagaggg caagcaattg gcatcagaac agtttagtca tctactatca
    20581 gaggtcactg taaaaggcta ttcagacatt gcctttgtca ttggtgggag tcttggtttg
    20641 gatcaatcca ttaaaaatag ggctaattta ttgatgagct ttggcctatt gaccttacct
    20701 catcaattga tgcgtttggt tttaatcgag caggtttatc gtgcttttat gattcaacaa
    20761 ggcagtccat atcataaata gcagttgttt cacatgaaac actacacatg gcatagaaga
    20821 agcgcgtgta tacctcaacc atacttctag ctttcattaa tagggctgtt gatttgcagc
    20881 cttactcagc tattgcctga tgataaaagc attaattgct ttatcgaact gatgatttgg
    20941 aggttttgtg attttagcct tagacgatgt caggcaaatg cttatcactc ttatgactct
    21001 cctacgggag tcagtagctt actattgtta gaaatacaaa aagccattag atactgacta
    21061 atggcttttt ttactatttc tgatctcagc aggattcgaa cctgcgaccg ttcgcttaga
    21121 aggcgaatgc tctatccagc tgagctatga gacctcaacc accttatttt aacaaaaaaa
    21181 ccttatgcct gtcaatgctt atttttgata agaagcttca ctgccctaaa cgtgcggtga
    21241 tatgtctttt agcagtttgt atcagaggag caatgtgtta tgttttctag catgtttggg
    21301 gtaattagac ttgttttaga ctgtttatgt caaaagtgat caaaaaatca agattttttt
    21361 gaaaaaagta tagacaaata aaaacattct gctataataa taagagtgtt aaggagagtt
    21421 actcctgaac ttcaggtccg ttggtcaagg ggttaagaca ccgccttttc acggcggtaa
    21481 cacgggttcg aatcccgtac ggactatcag aattgtcttt gtggcaattt ttttattttc
    21541 cggcatagct cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc
    21601 ctactgccgg agtgataaga cacttcctaa ggctttctta ggattttttt attgaccttg
    21661 aagagtgatt gtgatttgct aagaaactta aaaatacgct aatcgtctaa atgataggct
    21721 tctctttttt gggactaagg aacacgtgag ttatggaaag tcatgtgttt tgataaatat
    21781 ccttaaatca atagaccagc taaaaacact tgattttgat acctggaagg gctgtaaaat
    21841 caagcgtttt gcttatatat ggaaattgct gtttaagctt ttagcttggc tgtttgcctg
    21901 agtaagtagt aatgtaagaa gctgtaaagc aagataccaa taaatgagag cagtaagcct
    21961 aatgtaaagc catttggaac aaaggtgagt actaatttac cagatccttt tggaacatct
    22021 atcctaataa aaccaccttg agccttttta agagccactg gtcggccatt tagtcttgct
    22081 gtccagcctt tgtcataggg aagggtaaaa atcatagagc cttctgattt ggccttgtaa
    22141 tggctaatga cctgattgct acgggtgtaa gtagtaacct ctttttggtt aatcgcattc
    22201 atggctgcca gatagttgtc actatttaaa ctgtagaagt gtggggtagc aaaggaaata
    22261 tttttgtttt tcggaaacat aatagcaagg gttaaggttc ttcctttttc aaagtaccct
    22321 aagtcaaaga atgaaaaagc gttgtcagta gtgtactcgt aggtctgatc atcaatacgg
    22381 atcctaacag ctgttgcatt gtgatttgaa aagctaatat ttggaagact taagtagagc
    22441 tgcctatggt ttggtacagt aacctgataa tgaacaatgg ttgttgacgt attctcagca
    22501 gcctcccctg aaattctccc attaaatacc tgagcatttg atattagctt agaaggctct
    22561 agctgaaaat aggtgagcct ttttccactc agctgattca gcagcttggt ttgattgtca
    22621 agtgtgttga cagttaactt gacatctttg taaatgttat ctgttaagat agctagattg
    22681 ctgctatagt gattttgata gagtgtagtg tgatgactgg aggctatcct tgaaaagcca
    22741 aatttatgaa gctgatggta gctaagattg tattttatcc ctaaaagact atccatgatg
    22801 agagtgttgt tttgatagcg aaggtttaga tttgttccag cagactggta gcctagacga
    22861 tccagaaggg agctggagtg acgatttcgg atagatgaaa attgagaaat gccattatag
    22921 ctgtatttca tactatcatt gcctgtttgt ggtaggagct gctccagtct gaaaaactga
    22981 tcattgctat cagctgtttt cttgacaagt ctgtcaatat cctgtaaagc tctactatag
    23041 cccttacgtg atggaaacac ccattcatga tgaatgccat taagctgata ataggtattt
    23101 aaactggttt ctaaacagct aaacagtagg gtaaaaaaga ttaaaaatgg cattggtaca
    23161 gaggtttttt gcatgcttaa caataaaata agatatgccg ctaaaaaggc aagacttaag
    23221 atcaataaac taggctgtaa aaagctatac tgatccattg tcagataagg aagtgttaat
    23281 aagcagctta ataatataaa ggcaaagatt attctagtgt tagtaatgtc tttttgtcta
    23341 gaaagggctt cgcaggctaa aataatgata atgattgaaa atgaccacga atagcggtgc
    23401 aaaaacatat tgggtccatg catgccctgc caaaataaat ctaagggctg aagataaaag
    23461 ctagccatga tgagtcctaa aagcagccca tagcccagtc ttaagcgcca gctaatagat
    23521 tttaaggtga aaaagacgat acttaacaat gaaggcaaca gaccaataaa tatcatggga
    23581 atcgcattaa actttgtcgt atcataggca ccaagtgata gctttgctaa taaatcaaag
    23641 gctcctatag gcttaatgat aatctgattg attggagaga gtgtttcacc gtaggctgtt
    23701 aggtctagat aggccggtat gagtataaaa gcacttgtta aggctgataa gattgacact
    23761 gatgtaaagc ttaaacaggc tcttaaccgt cttttccatg tgtctagtga tataaggttg
    23821 actagaaata ataaaaaaat aaagatagca accatatatc caaaataata atgctggata
    23881 aagagaagac taagtgagct ataataaagc aagggcttgg tttgagtaat cagccgatag
    23941 agccccagta agacaattgg tagaagaata aaaacatcta accagttgtt aagctctagc
    24001 tggcttgtca gaaagctcat tagggagtaa gagactgata atgtcaggac taaaaagggt
    24061 ttgattttag ggtaaatacg atgaaaggag aaataagcgg caagcccgat caaaccaaat
    24121 ttaataagtg tcaagagata gatagcatct ggcatggatt gcagattaaa aaaatagaca
    24181 agaggagaca aaaggctgcc tagataatag ctagccagag caaaaaagtt tacacctagg
    24241 ccactggtaa aggtgtaaaa aatactatca gccccatgaa gaatatttct tagggcttgc
    24301 gcaaaaataa catattgatg aaagccatca ctagctaaaa tggttttctc actgccatat
    24361 gaaattccca ttgacaaaag aacaaaaaac attatcaaaa agggaaggag gaagctagca
    24421 atgtcataaa caagagacca tgctttaggt tttgtcataa ataagccctt ctatgatatt
    24481 tttgaaaaaa gagctagaaa tagtttccag ccctcagatg tcatcggtga tcatctctat
    24541 actttaatga tgatattgag caaagctcct tgtttcttcc ttatttccaa agctctgcta
    24601 ccttagcttg aacgtctttg ttttcaagga attcatcata ggtttcgtca atacggtcaa
    24661 tcacaccatt tttagaaata acaacaatgt gattagcaat ggtttggata aactcgtggt
    24721 cgtgactggt aaaaataaca gactctttaa aatctttaat cccgtcattg agacttgaaa
    24781 tagattccaa atctaggtga ttggttgggt catcaagaag gagaacattt gattttaaaa
    24841 gcattaactt tgatagcatc acgcgcacct tctcaccacc agagagaacg ttaacggatt
    24901 ttttaacctc atctccagaa aagagcatac gtcctaagaa accacgcaag aaggtatcat
    24961 catcttcacc ctttgctgca aattggcgga gccattcaag gatagactca tcgctagcaa
    25021 agtcacgtga gttgtccttt ggcagatagg agcgactagt tgttactccc catttgatag
    25081 tcccttcata gtcaatgtca tcagccagag cgcgcataag agctgttgtt tgaatgtcat
    25141 tttgtccgat aatggcagtc ttatcacctg gccttagaat gaagctaatg ttatctagaa
    25201 ttttgtcacc atcaacggtt acagacaaat tttcaactgt tacaaagtca ttgcccattt
    25261 cacgctcagc tttaaaattg atgaatgggt atttacggct agatggaata atctcttcta
    25321 gctcaatttt gtccagcatt ttcttacgag aggttgcttg ctttgattta gaagcattgg
    25381 cagaaaagcg tgctacaaat tcttgcagct ctttgatttt ttcttcggcc ttagcattac
    25441 gatctgcctg aaggcgtgca gctaattcag atgattgctt ccagaaatcg tagttaccga
    25501 caaaaagctt aatctttcca aaatcaaggt cggccatgtg agtacatacc ttgttcaaaa
    25561 agtgacggtc atgtgacacc acaataacag tattttcaaa gtcaatcaag aagtcttcta
    25621 accatgaaat agactgaata tcaagaccgt tggttggctc gtctagcagc aaaacatcag
    25681 gcttgccaaa aagtgcttta gctaggagaa ccttcacctt atcaccattg gtgagctcgc
    25741 tcatgctttg ataatgcaat tcctcaggga tatttaggtt ttgtagtaat tgagaggcct
    25801 cactttcagc ctcccagccg cctagctcag caaagcttcc ttctaattcg gcagcgcgaa
    25861 caccatcttc ctcagaaaaa tcaggcttca tgtaaatagc atccttttcc ttcatgatac
    25921 tgtaaagctg ttcatttccc atgataacca catcaatggc acgttcctct tcgtaatcaa
    25981 aatgattttg gcgaaggaca gaaagacgct catctggtcc taaagagata tgacctgttg
    26041 ttggttcgat atcacctgcg agaattttta ggaaggttga ttttccggca ccattggcac
    26101 caattaagcc ataagtgttg ccagctgtaa atttgatatt aacatcgtca aaaagttttc
    26161 gatcactaaa gcgcagtgat acgtcagaaa ctgttagcaa tttgtcacct cattttattt
    26221 atctaatcct cattgtacct aaaaaagccc cttttttcaa tcagaaaagg gcttagggct
    26281 tacataggca gcagcacatc tttgtcctct agtttgtaat gcttggttaa gctgaagcca
    26341 cgtcccatga cctgtgctgc tggcatgaca acgataaagg cagtgtcatc gatttctaga
    26401 attttttcct gtaaagctgg caactcatag ccagaaacaa tggccattag catgatcttg
    26461 tctgatgttg tgtagcctcc tcggatagga atcttagaga caccacgatc cataacacct
    26521 gtaatataag ccttgatggc ctgatattcc tttgaaataa tcatgacatt cttagaagag
    26581 tcaaagccat tttccatgac actaatgaca tagccaataa cgagcagtcc gatcgtagaa
    26641 tacatgacat catcagcaga taaagcgatg aatcccatta aaacactaat gccatccaca
    26701 atagtcatag caactcccaa tgataatgga gaatatttgt gtaggatttg tgtcagaata
    26761 ccagtacctc cggttgatga atttccccaa aagaccattc caaggccgat cccacaaatg
    26821 atgccaccaa aaatagctgc taataattgg ttatgagtga gtgttggaag ctggctggtt
    26881 aggcgtatag caatagggta aatccatgaa ccgtagaggg ttttgatgag attttgttta
    26941 ccaagaaaga agtagcataa aatcaataaa gggatattgc ttagcattaa aaagagcgag
    27001 gggctaattc caaacagcgc tttgataaca actgaaatcc ccaccatacc acctgaagca
    27061 atattattat caacaaacat tgtgttaaag ccgatagctg tgatgaagga accaatggtt
    27121 acaaatagta aatccattac cctttttttc atatttaata cctcctttat cgtttagtaa
    27181 acataataga cccattatct cctaaaagaa tagaaaccgt caagccctat tgcttaaaaa
    27241 tcttagcagc ttgacaaatc acttaaaatg tcatagaatg accctaaact agatgagtaa
    27301 tctttccctt gtttttagag agctagtggt tggtgagagc tagcagcaag caagatgaaa
    27361 tgggctagtg gatcttttga gaggaaacca taactttcag gcctggcacc ccttatcgtg
    27421 caatttcttg agttgagaag atgagatagt attgattgat cagagatact aattgaggtg
    27481 gtaccgcgta tttattgtaa tgacgccctc acgcaagcct tttgcgtgag ggtttttgat
    27541 gtcataaaat cagtattaag gagaaatcat gacaaaacca gttattttaa caggagatag
    27601 accaacagga aagctacact tgggacatta cgtcggcagt cttaaaaatc gtgtaagcct
    27661 gcaaaatgaa aacaagtaca agatgtttgt ctttttggca gatcagcagg ccttgacgga
    27721 tcacgccaaa gaatctgaga tgattcgtga gtctattttc aatgtcgcat tggattatct
    27781 ttctgtcggc ttggatccaa gtaagtcaac tatttttatc caaagtcagg ttcctgaact
    27841 tgcagagtta acaatgtact atatgaattt ggtgtctctt gctcgcttgg agcgtaatcc
    27901 aaccgttaaa actgaaattg ctcaaaaggg ctttggtgag agtattccag caggcttttt
    27961 ggtttaccca atttctcaag ctgctgatat cacagccttc aaagctaatg tagttcctgt
    28021 tggtaatgat caaaggccaa tgattgagca gacacgtgaa attgtaagaa gctttaatca
    28081 tacctataag acagcctgct tgattgagcc agaaggtctt tacccagaaa atgaaaaggc
    28141 aggacgtcta ccagggcttg atggcaatgc taaaatgtcc aaatcactgg gtaacggcat
    28201 ctatctttct gatgatgctg acactgttcg tcaaaaagtc atgagtatgt ataccgatcc
    28261 aaatcatatt cggattgagg atccgggaca gctagaaggt aatatggtct ttcattacct
    28321 agatattttt ggccaaaaag aggacaaagc tgatattgaa gcgatgaaag agcattacca
    28381 aagaggtggc cttggagatg ttaaaaccaa gcgttatctg ctggatattt tggaaagaga
    28441 gcttgcgcca attcgccaac gccgattgga atacgccaag gataagggcg aggtctttcg
    28501 tatgctagaa gcaggaagtc aaaaagcaca ggcagtggct gcccaaacat tgtctgaagt
    28561 aaaggttgct atggggattc gttattttta atagcgtaga ggctgagaat gattcttggc
    28621 ctcttatctt ttcaaatgca cctatcactc atgagtcaaa acctgtcttt ttaatttaca
    28681 gaaatatata gaattatgtt attgacaaat gaatttagcg tgatatgata gtaacaataa
    28741 aaataggctg gggtaatatt ccctaaaaaa gaagaaaaga ggattgtgtt aatgtcaaat
    28801 tgggacacta aatttttgaa aaaaggctac acgtttgatg atgttttgct tattccggca
    28861 gaaagtcatg ttcttccaaa tgaagtcaat ttaaaaacca agcttgctaa aaatttgaca
    28921 ttaaatattc ctattattac cgcagccatg gacactgtaa cagacagtaa aatggctatt
    28981 gcgattgcgc gtgcaggtgg tcttggtgtt attcataaaa acatgtcaat tgctgagcag
    29041 gctgaggagg tgcgtaaggt caagcgctct gaaaatggtg tcatcattga tccgtttttc
    29101 ctaacgcctg agcacaaggt agctgaggct gaggaattaa tgcagcgcta ccgtattagt
    29161 ggtgttccga ttgtagagac cttagctaac cgcaaattag tcgggattat tactaatcgt
    29221 gacatgcgtt ttatttctga ttacaacgcc ccgatctcag aacatatgac aagtgagcag
    29281 ctggtgacag ctgaggttgg gactgacctt gagacagcag agcgtatcct tcatgagcat
    29341 cggattgaaa agctaccatt ggtagatgat aatggccgtc tttcaggttt gattacaatc
    29401 aaggatattg aaaaggttat tgagtttcca catgctgcaa aggacgagtt tgggcggttg
    29461 ctggtagcgg ctgcggttgg tgttacatca gatacctttg agcgtgcaga ggctttattt
    29521 gaagctggtg cagatgctat tgttattgat acagctcatg gacattccgc aggtgttctt
    29581 agaaaaattg cggagattcg cgcccacttc cctgataaaa ccttgattgc aggaaatatt
    29641 gctactgctg aaggcgcgcg tgccctttat gacgcagggg ttgatgtggt taaggttggt
    29701 atcggaccag gctcaatttg tacaactcgt gtcattgctg gtgttggggt acctcaagtt
    29761 acagctattt atgacgcagc tgctgttgct cgtgaatatg gcaaaaccat tattgctgat
    29821 ggtggtatta agtattcagg agacattgta aaagcccttg cagcaggcgg caatgctgtc
    29881 atgttaggct ctatgtttgc tgggacagat gaagctccag gtgagactga aatttaccaa
    29941 ggacgcaagt ttaaaactta tcgtggcatg ggatcaattg cagctatgaa aaaaggatca
    30001 agcgaccgtt acttccaagg ctctgttaat gaagccaaca agctagtgcc agaaggtatt
    30061 gaaggacgtg ttgcttataa gggagctgcc tctgatattg tctttcaaat gcttggtggt
    30121 attcgctcag gtatgggata tgttggagct ggtactatcc gagaattgca tgacaatgct
    30181 caatttgtag agatgtcagg agctggtctg attgaaagtc acccacatga tgtccaaatc
    30241 acaaatgaag caccaaatta ttccatgcat taatcctgca ggtgtttact tgatgtagta
    30301 tttgacatat ctattttaaa agctgagata ttttctcggc tttttttgtt gcacgattaa
    30361 accatgatta gaaatgacag cttgctagcc ctagctattt gctttttagc tttgtgatat
    30421 ttcaatgcta ggctaatgat caaatcatac tgaatgctct taagcgtaat accttccaaa
    30481 aatggcataa ccctaaaagg attaacttaa atagacatga aatattgtga aatatagaaa
    30541 tcatgttaaa ataatattat taaatagtta aattaaaaag aaatatacca aaatgattcc
    30601 atttattttt gggaatttat cgataagtat aggaatgata taggagtata gacatgaata
    30661 ggtttttaaa gatcagtctg cttattgttg gtgttattgt cattatgctt ggcatggaag
    30721 taaagcatag aatggatata tacgatcaaa tcaagcagga ggagataaaa attgcccaaa
    30781 gtaaagaagc aattgtgatt tatgaacagg agttaaaatg gttggaccca aatgcattga
    30841 caaatgaagg gactattaaa tcctattcta ttgatttaga ctcaataact cttaatccaa
    30901 tgggaggctt ttccattgct ttacatataa acaaaaatcc aaagtataag tatcgaataa
    30961 gtttaatgtg gaatacacca atgagagatt tatgtgtggg aggatcctct ttgtcgccag
    31021 aattacaaga attgttagat aggtaatgat tatgacaggc tatcagaaac aattgattgc
    31081 accaaagaac aatataattt tcatgaaaag gagcatagtt atgaaaacat tgttaaaact
    31141 cattgtattt attgttggta ctcttgtact tatgcttggc atggaggtaa agcatagaat
    31201 ggatacatac gatcaaatca aacaggtaga gctcaaaaac gcgcatagta aagaagtgat
    31261 tgaaatgtat gaacaggagc taatatcaat ggatccccag gccctaacag atgaaggact
    31321 tatcaagtcc tacactatcg actcagattc actctttatt aatccgatgg gaggcttttc
    31381 cattcattta attatcaatg atgatccaga tatttacttg agagttggcc ttggtagata
    31441 tgatatggaa agaaatttgg agattgatgg tatctatcgc tcagaaaagt tagaaaaact
    31501 actaaaagga gtggagagat gaaaacattg ttaaaactta ttgtatttat tgttggtgcc
    31561 cttgtactta ttcttggcat ggaggtaaag catagaatgg atatatacga tcaagtcaaa
    31621 caggtagaac tcaaaaacgc gcatagtaaa gaagcgatag acatttatga aaagaagtta
    31681 aaaagattgg atcctcaggc cctaacagat gaagggctta tcaagtctta tactattgac
    31741 tcagactcaa ct
//
LOCUS       DARYMD010000024        31486 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYMD010000024 DARYMD010000000
VERSION     DARYMD010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31486
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..268
                     /locus_tag="TU818_001023"
     CDS             <1..268
                     /locus_tag="TU818_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0923848.1"
                     /translation="PKPEPKPEPKPGPKPGPKPEPKPEPKPEPKPEAKKPEQPKPMTK
                     PGAKKPEQSLPSTGDIRNPFFTPAAIAIMIAAGTIAIPKRKEED"
     gene            complement(514..828)
                     /gene="trxA"
                     /locus_tag="TU818_001024"
     CDS             complement(514..828)
                     /gene="trxA"
                     /locus_tag="TU818_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL0923849.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            1008..2327
                     /locus_tag="TU818_001025"
     CDS             1008..2327
                     /locus_tag="TU818_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL0923850.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQERILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEVASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGLYAVGDVNGGPQFTYTSLDDFRIVFGQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETNEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(2667..5003)
                     /locus_tag="TU818_001026"
     CDS             complement(2667..5003)
                     /locus_tag="TU818_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL0923851.1"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IETAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(5076..5621)
                     /locus_tag="TU818_001027"
     CDS             complement(5076..5621)
                     /locus_tag="TU818_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL0923852.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALVSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVMVSVLFLSMALTVLATIPMPFIQGRLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(5621..5932)
                     /locus_tag="TU818_001028"
     CDS             complement(5621..5932)
                     /locus_tag="TU818_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923853.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            6050..6958
                     /locus_tag="TU818_001029"
     CDS             6050..6958
                     /locus_tag="TU818_001029"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL0923854.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNANPYVRLAAKKDGVTLM
                     LYTSGKLVLQGRQAAKLAQELDLQETPADQRPAPSSAQDIPLIGSDEVGNGSYFGGIA
                     VVASFVQPEEHALLRQLGVDDSKNLNDKSIAQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KGKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQILAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            6983..7582
                     /gene="lepB"
                     /locus_tag="TU818_001030"
     CDS             6983..7582
                     /gene="lepB"
                     /locus_tag="TU818_001030"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL0923855.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            7811..10210
                     /locus_tag="TU818_001031"
     CDS             7811..10210
                     /locus_tag="TU818_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL0923856.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPTSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDEILKNPSRLNEISSLSKANREAFVAKLKANYGTEQVIAALADLG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKLADSLAEQLGIESASPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEDGIQKHLTRLLQQPLTKEPSQDTIDQEIQAIQEELAITYDKI
                     QKQAISQALTSKVFILTGGPGTGKTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGR
                     AARRMNELTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AINSNTQLIIVGDSDQLPSVGPGQVLADLLKVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLANQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIIMDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPHNFLAIDPMIGLTEDDMLTFFKKK
                     S"
     gene            10306..10791
                     /locus_tag="TU818_001032"
     CDS             10306..10791
                     /locus_tag="TU818_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923857.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDNPQSIE
                     E"
     gene            complement(10934..12037)
                     /gene="dinB"
                     /locus_tag="TU818_001033"
     CDS             complement(10934..12037)
                     /gene="dinB"
                     /locus_tag="TU818_001033"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL0923858.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKN
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTTNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRMRKSISSERTYAKLLYQEADIKAEL
                     SKHARRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            12246..14570
                     /gene="pflB"
                     /locus_tag="TU818_001034"
     CDS             12246..14570
                     /gene="pflB"
                     /locus_tag="TU818_001034"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL0923859.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            14876..15154
                     /locus_tag="TU818_001035"
     CDS             14876..15154
                     /locus_tag="TU818_001035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923860.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASETHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENHKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(15318..16259)
                     /locus_tag="TU818_001036"
     CDS             complement(15318..16259)
                     /locus_tag="TU818_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL0923861.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGNHAGSAGLFSTIRDL
                     ERFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIHRTFDRNSPR"
     gene            complement(16256..17011)
                     /locus_tag="TU818_001037"
     CDS             complement(16256..17011)
                     /locus_tag="TU818_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL0923862.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRVVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIVPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(17504..18352)
                     /locus_tag="TU818_001038"
     CDS             complement(17504..18352)
                     /locus_tag="TU818_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL0923863.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGDKSSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVAAVAAF
                     KFLYIK"
     gene            complement(18454..18906)
                     /locus_tag="TU818_001039"
     CDS             complement(18454..18906)
                     /locus_tag="TU818_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL0923864.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLRYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(18926..20125)
                     /locus_tag="TU818_001040"
     CDS             complement(18926..20125)
                     /locus_tag="TU818_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0923865.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYF
                     VRLFNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIILCSVLIAVVVLGAFAFPVTDIALNSEQLAKTKSWTVDSFIERKALFITL
                     IAFLMGIAYASVLGFQKLYTTDIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFHQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            20294..20953
                     /locus_tag="TU818_001041"
     CDS             20294..20953
                     /locus_tag="TU818_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL0923866.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            20974..23259
                     /locus_tag="TU818_001042"
     CDS             20974..23259
                     /locus_tag="TU818_001042"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL0923867.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKL
                     FFHFQDTDYPLSHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(23365..23757)
                     /locus_tag="TU818_001043"
     CDS             complement(23365..23757)
                     /locus_tag="TU818_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL0923868.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGRAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(23911..24168)
                     /locus_tag="TU818_001044"
     CDS             complement(23911..24168)
                     /locus_tag="TU818_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0923869.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFFGRRFGFYEIKSACLLIAFLL"
     gene            24347..24721
                     /locus_tag="TU818_001045"
                     /pseudo
     CDS             24347..24721
                     /locus_tag="TU818_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678526.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(24979..25761)
                     /locus_tag="TU818_001046"
                     /pseudo
     CDS             complement(24979..25761)
                     /locus_tag="TU818_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(26278..27786)
                     /locus_tag="TU818_001047"
     CDS             complement(26278..27786)
                     /locus_tag="TU818_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0923870.1"
                     /translation="MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPCYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSALLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILNG"
     gene            28037..28933
                     /locus_tag="TU818_001048"
     CDS             28037..28933
                     /locus_tag="TU818_001048"
                     /inference="COORDINATES: protein motif:HMM:NF012162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0923871.1"
                     /translation="MKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQLYYGWNDGTR
                     QSSPYFLYVSPKNAPKRELKDEYVVYCFNKKLYWPDQWESIYSNFNDIRSPYNDLPVY
                     EKKLGYDGIFKQYAPDYKKDISDIASALVAVLSNGYPTNKSQLSTSYHLNNDSSRKVT
                     QLAIWYFSDSLTKEYLKDTGGYNLNDMEKKALDFLISKGEDSKLKSEQSNYSLDIYVY
                     QSGGHDHMKDYQNLLGSTLIPKEPLKPQLGGFSGHNGNGLSGLEGGSSGSQETNEDGK
                     KGLIGFHGGLSGSEGKRDPFQD"
     gene            28930..29193
                     /locus_tag="TU818_001049"
     CDS             28930..29193
                     /locus_tag="TU818_001049"
                     /inference="COORDINATES: protein motif:HMM:NF014980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein"
                     /protein_id="HEL0923872.1"
                     /translation="MKGEAGAPDTPQKPNDPLQSLEGGNSPIVEQNYGSTEGYHGQSG
                     ILEETEDTNPPGIILGGSGNVETRSSSDGAWRWSSWRIRRNDT"
     gene            29120..29926
                     /locus_tag="TU818_001050"
     CDS             29120..29926
                     /locus_tag="TU818_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL0923873.1"
                     /translation="MSKRDPHLMGLGGGLAGESGETTPKPGQTGGHGPIIETTEDTQK
                     GMSGQSGGTIESENTKKPEVMIGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVM
                     IGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVMIGGQGQIIDFSENTQSGMSGQ
                     SGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSGGTTIVEDTKKPTPKPKPAP
                     APIVNDEKPNKGTQLPQTNDMKQLTLSIIGAMSMLLVLCLSLFKRPSKKD"
     gene            complement(30298..31344)
                     /locus_tag="TU818_001051"
     CDS             complement(30298..31344)
                     /locus_tag="TU818_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL0923874.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQEKRS
                     VHIEVAKEVVKISSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGD"
     gene            complement(31346..>31486)
                     /locus_tag="TU818_001052"
     CDS             complement(31346..>31486)
                     /locus_tag="TU818_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEL0923875.1"
                     /translation="WEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKTVWGLGYKL
                     EG"
BASE COUNT         9409 a         7414 c         6280 g         8383 t
ORIGIN      
        1 gcctaagcca gagcctaagc cagagcctaa gccagggcct aagccagggc ctaagccaga
       61 gcctaagcca gagcctaagc cagagcctaa gcctgaagct aagaagcctg aacaacctaa
      121 accaatgact aaaccaggag ctaagaagcc tgagcaatca cttccatcaa ctggtgacat
      181 cagaaatcca ttcttcacgc ctgcagctat tgctattatg atcgcagcag gtaccattgc
      241 cattccaaaa cgcaaggaag aagattaaac aaattaacaa tccccatatt tcaacaatga
      301 tacacaagcc cctacttgtg tccacctcaa aagcagtagc cagtcgcgcg gctactgctt
      361 ttactatgct ttttttacac cagctctgat agcagctaat aacaaaaaag attgaagaca
      421 cagcttattg ggtccccgat ctttttttgg tcatacaacc aacagcagct cttgaggctt
      481 gctgtccttc taagaggctg ttggcttgtt gctttagctt aattctgcta cgatagcctt
      541 gatttgatcc ttggtatgga cgcctgctac ttgcttgaca accttaccgt cctttttgaa
      601 cagcagggtt gggatagaca taatgccaaa ttgttgagca gtattggggt tgtcatcaac
      661 atctagcttg acaatcttaa gctcagcttc gtcaatttct gctgctaatt gatcaaggat
      721 tggcgcttgc attaagcaag ggccgcacca ggttgcccaa aagtccacaa ggactaggcc
      781 ttcattagtt tctgcttcaa atgttgcatc tgttacgata tgtgccattg taatctccgt
      841 tcttatagtt tataagccta ttttagggga aaacgactga taatgcaaga atctgatacg
      901 aagacctcgg tcttatgatt taagaaaaat ctggcgtagc cattttaaga caaatacgct
      961 ggcctttgct acaatgacct tatcttaaca actaaaagga ggctactatg gaagcatacg
     1021 agcttattgt gattggattt ggtaaggccg gaaaaacttt ggctgccaaa atggcgcagc
     1081 taggaaaaag agttgccctt attgagcaga gccccactat gtatggcggg acttgtatca
     1141 atatcggctg tattccaaca aaggccttaa tcactgctgc tgagcataat gctagctttg
     1201 cagacgctat ggcgcacaaa gatactgttg ttcatcgtct tcgccaaaaa aatgagcagc
     1261 tgctagctca gtctggtgtg acactttaca acggtaaggc aagctttgtc tctaataaga
     1321 cgattcaagt agaagcaggg caggagcgga tcctcttaga gggcaagcat atcgtgatca
     1381 ataccggagc tgtttcaaat cgctttccga tacctggtct agcagatagt cagcatgtgg
     1441 ttgatagtac agggattcta gctctcactg agcagcctca gcgcttggct attatcggtg
     1501 cggggaatat cgggctagag gttgccagtc tttatgccag cttaggcagc gaggttacta
     1561 tgtatgaggc tgcacctgct attttagggc gctatgagcc ggttgtcgct gagctggcac
     1621 aggattacct ggaaaaagct ggggttacct ttaagctctc tgcgactgtt gagctgattg
     1681 ctaatgatga agcaggtaga gttctagtga ctgctaatgg caagacagaa gcctttgatt
     1741 gtctcctcta tgctatggga cgtaagcctg ccactcaagg ccttggcttg gaaaacactg
     1801 acattaagct tgatgatcgc tatgctgtcg tggtagatga ttattgtcaa accactgtcg
     1861 aggggctata tgcggttggt gatgttaatg gcgggcctca atttacctat acgtccttag
     1921 atgatttcag gattgtgttt gggcagctaa caggcacaag ccagtacaac cacaaagatc
     1981 ggggctatct gccaacaaca gtctttatcg agccgccact ttcacaaatt ggtctaacag
     2041 aaaaagaagc aaaagagcag ggactgccct acaaggctaa tgagctcttg gttgccaata
     2101 tgccacgcgc ccatgtcaat aacgacctca gggggatttt taaggtcatt gtcaatacag
     2161 agactaatga aattctaggg gcaaccttat ttgctaacaa ttctcacgaa tacattaacc
     2221 tgattaagat ggctatggat aaccagattc catataccta tctcaaaaac cagctcttta
     2281 cccacccgtc aatggctgaa aatcttaatg atgtctttaa cctttaaaag aacctcaacc
     2341 tcacctgcat agcaggtaca acagccaaac tattaaaaaa acaaactcct ttttggctgc
     2401 ttatcacatg gataggcggc tagcaaaagg agcttgtttt ttcttgtatc caatcagcag
     2461 gctagcagct gctcatggtc taaaggaact agctaggctg ggacacgttg gtagcaaaag
     2521 tccagcaaga ctcactagct gctgtcatga gctttgaaga gcagcactta gggaacacgc
     2581 ccagtagctt tctttgggac gcttggctca cctagggctc aatcagcttg agtaaaaagg
     2641 ggctttattt gaatcaagag gatcaattag cctagattag ctatggtaca gcctgagccg
     2701 ccagcatttt gcggggcata gccaaagctt ttgacatgct tgttgcgtcg caagtacttg
     2761 ccgaccgctt cacgtataac acctgtacca ataccatgta tgatgtcaac ctgactcatg
     2821 ttgttaagca aggcttggtc gataaaggca tctagctcct gcatggcctc ctcatagcgc
     2881 ttgcctcgaa ggtctaagcg agcgcgcggc ccttttcctg tagctgcttt tttgacgacc
     2941 ttgacagctc tcttcttagg ctgctgcgct tcttctttta gcttaaccaa gctgaattcg
     3001 tcttccttga gggtcaactt gatcaggcca acctgagcct cccacctctt gtccttaagc
     3061 tgggcaagca aggttcctct ttgcccatag gcggtaacaa tgatgtcatc acccacacga
     3121 ggagcccgcc attttttcgc ttttttcagc accttatttt gcgacaggct ttgctctggc
     3181 gcaagctgct ttaggcgatg cttggcttcg ataatttcgt gcggctttag ctctgccttt
     3241 tcatgcagct gacttaaaat gctatcactt tctgccaagg ctatatccac aatctcacgc
     3301 gcttcaaggg ctgccttttc caattccttg tccttagcgt gggagaactc gttatagagc
     3361 tttttaacag cacgattgaa tttgaggtta tcctgctcga cctccttgat atgctcaagg
     3421 cgcttgcggc tttctaacgt ttgctgctct agttgctcaa tgatacgatt gacatcatga
     3481 tcagttgcgg tcatcgcctg agcttccttg acgatgtgct ctgctaagcc caatcgtctc
     3541 gcaatgtcaa aagcatttga gcgaccaggc actccttgca tgaagcggta agtaggcttt
     3601 aggctgacat tgtcaaaggc catgctggca ttttcaacat aggctgtctc aatcccatag
     3661 gcctttagct ctgggtaatg ggtagtggcc atcgtcttaa tattggtcag acgcagctgc
     3721 tccaaaatag ccatagcaag gctggctcct tcctgtggat cagtccctgc tcctagctcg
     3781 tcaaagagga tcaagctgtc actgtctgcc tgattgagaa tctcaacaat gtgagtcata
     3841 tgactggaaa aggtagacag gctttgctca atggattgct catctccaat atcagcataa
     3901 ataccattaa aaactgccac cctggagccc ttgtcagcca aaataggcag ccctgactgg
     3961 gccatcacct gagcaagccc caaggttttg agcatgatgg tcttaccacc tgtattagga
     4021 ccggtgatca caattactgc taagtcattt gcaaaatgca gatcatttgc cacagggttt
     4081 tgaatcaagg ggtggcgcgc attgagcagc tgtaagcttt tatcgtcaga aatcactggc
     4141 acagttgcct gtttggcttg catataaagg tattttgctc tcacaagatc taaatgtcct
     4201 agtagccaag cgttattcct aagagatcga ctatgcggac gcagctgctc tgacagctca
     4261 tgcaagattc gtccaatctc atggcgttca tctgtctgta gctgagtcag ctcctcattg
     4321 agacttacaa gcgctctagg ctcaatgtag accgtactgc cagaagctga catgtcatgc
     4381 acaacgcctg ccaccttatg acgataggtg tttttgacag gcaggacact tcggccatta
     4441 cgactagcaa tcaggctctc tgacaaataa gctgcctgtt tttttaggat atcctgcagg
     4501 agctgacgac tggcatgctc cttgtttgat atctgacgac gaatgctctc caattcagga
     4561 ctagcaaagc cttcaacaaa gcctgcgtca ttaatggctt ggagactccc ctgtaagcta
     4621 ggaaagctct ctattttttc aaagagtgct tttagagcga ctaaatcaac attttccaaa
     4681 tcagcgtaaa aacgacagac ctctgccgac acctgcagga gctttttaac tgctaaaagc
     4741 tcttgaatgc tcagatctgc ctctaaatcc aaacgctgca tgctttctga gacatctgat
     4801 agccctccca aggcaaaatg gtggtgctct acaaaaatag ccgccatttc ctcaagctct
     4861 gtaaagtaag cctgtatttt gtctttattc gcaataggct ccaacaagtc aagctctagc
     4921 tgcccctgct ctgtctgtaa ataaggccaa aattgctctt taaccttttc aaattctaac
     4981 tgttctaaaa tctttttttc catagttctt attataccta aaaatcactt aaaatgtggg
     5041 acactaaaca aaaagagacc agagagactc tgacctcaaa gaatagctgt tacccataat
     5101 tgcctgagaa tgcttgagat aaagggacaa tgctcaacca agaggcgaga caaaagactg
     5161 ccatgtaggc gcccttgaat aaagggcatg ggaatggtag caagaacggt caatgccatg
     5221 cttaaaaaca aaaccgaaac catcaccgcc agcaagccac tggctagctt agcctcaaag
     5281 ccatcaaaat aatccaccgg cgcaaggtgc accaagacac ccgccaatcg aaccacagca
     5341 tagcctactg tagacagtat aaaaaatgct atccctgcat aataaacctt atccaattca
     5401 aaaatattaa tatccttaaa aaataaggta gctgctccct cagcaggatt agaataaggc
     5461 acccatagag ccagcttgcc tgccagagcc ttatagccat gatgggcaaa caagagcgac
     5521 accaaggccc caaaacaata aaaggtctga aggataagcc ctctattgta gccaatgtaa
     5581 aagctccaag aaagcagtaa caatataagc actgagagca tcatgacacc tcatctgtat
     5641 ctgcttgact agccttttcc tgaatacctg ccagtgcctt ctcacgcagc tcgacaatct
     5701 cagcttcgat tttttcaatc tcaatctctc tactcagttg ggctgacagg gtattgatgg
     5761 tcatcaaaat agcaacggtt tcgtcgtctg cttctggcag acgctccttg atggcctgat
     5821 atttttcctt tgccacacga tcaacctctt ccataaagag gttgtctttg tccgttgtca
     5881 atgttaatgt cttctcacca aatgttaatt tgtaacgatt aatattcttc ataggctcac
     5941 ccctttagca ttatacccta aaaatgactt ttcgtaaaat tgtgaaatta atctgagatt
     6001 gcatggaatg atttcccata acaggacatt ttatgttaaa ataatgttca tggacacctt
     6061 agttttcaaa atcaattccc aagtcagcag cagcctgatc aagcagctag caccataccg
     6121 cataagcaat gccaatcctt acgttagact ggctgccaaa aaagatggtg tcacactgat
     6181 gctgtatacc tcaggcaagc tggtgctgca aggcagacag gctgcaaagc tggctcaaga
     6241 gcttgatctg caagaaacgc ctgctgatca gagacccgca ccctccagcg cacaggatat
     6301 ccccttaatt ggtagtgatg aggtgggaaa tggctcttac tttggaggca ttgctgttgt
     6361 tgctagcttt gtgcagccag aggagcacgc cttgctcaga cagctcggtg tcgatgattc
     6421 taaaaacctc aatgataaga gtatcgccca gatcgctcct gtcctaaaaa agcatattca
     6481 acacagggcg cttttgctat cgcctaaaaa atacaatgaa atggtaggta aggggaagcc
     6541 ctacaacgct gtttctgtca aggttgctct tcataatcaa gcgatttttc tgctcttaaa
     6601 cgacggagca agaccagaaa aaattgtcat tgatgccttc acaagtcagg ccaattatga
     6661 caaataccta cagcaagaaa aaaatcactt tcgtaatccc ttgacctttg aggagaaggc
     6721 cgaaggcaaa tatctggcag ttgctgtcag ctctatcatt gctagacagc tatttttaga
     6781 caatcttgac aagctcagtc aagatctggg ctaccggttg cctagtggtg ctgggcgtcc
     6841 atctgatcag attgccagtc aaatcttagc cgcctatggt atggcaggct tagagcattg
     6901 cgctaagctg cactttgcaa acaccaaaaa agcccaagcg ctactaaaaa aacaataatc
     6961 ttagaaaaat aaaggaaaag tcatgaaaca atttattaaa gaatggggag cttttaccct
     7021 ttttatccta ctttttggac tctcacgttt gttcctatgg cagcctgtca aggttgatgg
     7081 ccactcaatg gacccaaccc tagcacatgg cgagaggctc attatcttca acaaggctaa
     7141 gattgatcgc tttgatattg ttgttgccag tgaggaggac gagaacggac agagaaaaga
     7201 gattgttaag cgtgttgttg gcatgccagg tgataagctg tcttatagaa atgacactct
     7261 ttatatcaac aacaagaaaa caaaagagcc ttatcttgat acctacctga cgagttttaa
     7321 aaaggacaaa ttacaatcaa cctatgctta cagtgatctc ttccaagagc tggctgaaaa
     7381 tgctgctgcc tttaccgtca actccgaagg aaaaacagaa tttgacatca ctgttccaaa
     7441 gggcgaatat ttcctactgg gtgatgaccg cattgtatct cgtgacagcc gcgaggtcgg
     7501 ctcctttaaa aagcaggaca tcgttggtga ggttaagttc cgcttttggc cactcaataa
     7561 aatcaatctc ttccctagat agcaggcaag ctaaagctat tttctagcag ggctgatata
     7621 ggctctatgc ccacagcagt aaagactcag ggcagcaata gcctctatct atatctgctt
     7681 atctatccat accaagaggc ttgatgtgct atccaagcac tcagctagct ttagagaagc
     7741 agctattgtt gacgttctaa aacctgccgt tgtgcaggtt ttcgactatc ttgcacagaa
     7801 aggtaccgtc atggaacact tttttacagg cactgttgac cgaattatct ttgacaatgc
     7861 gtcaaatttt ttcaaaattc tattactggc tatagaggat actgatagtg attttgatga
     7921 agctgacatt gtcattacag gcactatggc tgagatcata gagggcgaag cctatacctt
     7981 ttggggtgag ctgacccagc acccaaggta tggtcagcag ctgcgcctga gccgctatca
     8041 aaaggctaag cccacctcag caggtctcgt tagctatttt tccagtgagc atttcaaggg
     8101 cattgggcaa aaaacagctg agaaaatcat tgccctttac ggtaataatc ctattgatga
     8161 gattttaaaa aatcccagtc ggcttaatga gatctctagc ctttctaagg ctaatcgtga
     8221 agcctttgtg gcaaagctta aagccaatta tggcactgag caggtgattg ctgccttggc
     8281 tgatctagga ctggccaatc gctttgcctt tcagctattt gacaaataca aggaagaggc
     8341 tgttcatatc gtcaaggaca atccttatca actcattgag gacattcaag gctttggctt
     8401 taagctggct gatagcttag ctgaacagct aggaattgag agtgcctctc ccaagcgctt
     8461 tcgtgcggct ctgctgcatt gcctgttgga gcaatccatc aagcgaggcg acacctatat
     8521 ccaggcacgt gagcttttgg cgctgaccat tagcctatta gaggacacaa ggccagtcga
     8581 atgcgaccca gctattgtcg ctaatcagct aacccagctc atcgacgagg gcaaggttat
     8641 gactattggc acgcgtgttt ttgacagcag cctttattat gccgaagacg gcattcaaaa
     8701 gcatctgaca cgcttactac agcagcctct gactaaggag cctagtcaag ataccattga
     8761 ccaagaaatc caagccatac aagaggagct tgctataacc tatgacaaga tccaaaagca
     8821 ggccatcagc caggcactga ccagcaaggt tttcattcta acaggaggcc caggcacagg
     8881 aaagacaacc gttatcaggg gcattttaca ggcctatgcc agcctgtacc agattgacct
     8941 gaaacaaaag gatattccca ttatcctagc agctccaact ggtcgagccg ctcgtcgtat
     9001 gaacgaatta accggtctag caagcgcaac tattcaccgc catcttgggt taaacggaga
     9061 caatgattac caagcaatgg aggattattt agactgtgat ttgctgattg ttgatgaatt
     9121 ttccatggtt gatacctggc tggccaatca gctattaaca gccatcaatt ctaataccca
     9181 gctgatcatc gtaggagata gcgaccagct gccttctgtc ggtcctggac aggtactagc
     9241 tgacttgcta aaggttgatc ggatccctca cattaccctt gacaagattt ttcgccaatc
     9301 agaggagtca accattgttg atttagccaa ccacatacgc caaggcattc ttgctcctga
     9361 tttttgtcag aaaaaggctg atcgctccta ctttgaagcg caagcgccat tcattcccgg
     9421 catgatgaca aagatcgtac aggctgccct aaaaagtggc atcccagctg aggaaattca
     9481 aatcctagcc cctatgtaca aaggactagc aggcatcaac agcctcaacc agctcatgca
     9541 aaacctcctg aatcctctag ctaatcagac agaatttctc tttaacgaga cggcctttcg
     9601 taagggagac aaggtacttc accttgtcaa tgacgctcag cttaatgtct tcaatggtga
     9661 tattggctat atcacagacc tcattccagc caaatatacc gaatccaagc aggacgaaat
     9721 catcatggac tttgatggca ccgagatcgt ctacccaaga aatgaatggt taaaaatcac
     9781 ccttgcctat gccatgagca ttcacaaatc tcaaggcagt gaatttcagg tggtaatcct
     9841 gcctgtcacc cgtcagagtg gtcgacttct gcaaagaaac ctcatctaca ctgccatcac
     9901 cagatcaaaa agcaagctca tcatgctcgg agaaatagcc gcctttgaag aggcaatcaa
     9961 aaaagaaggt gacaagcgac acacctatct cgtacaaagg cttcaagtgg ctgaagctga
    10021 tgaccataca gcagctgctt cagtaaagga atcaaatcag tctagcctat ctgtaatgcc
    10081 agctaccagc ccacaaaagg aacaagagca gcctccttat ctgctcaccc ctcataattt
    10141 cctagctata gaccccatga ttggtctaac cgaagatgat atgttaacct tttttaagaa
    10201 aaaatcataa tatattaaaa aagtaaggca caatccttat tcctatgcta taatatccat
    10261 gtatcatctt aaaagtacaa taacataaca ttcaaggaga cttatatgat ttcatacgaa
    10321 caagtacgac aagcactcag aacatcaact attacgatca ttatcatcaa tgctatcagc
    10381 atggttatca ccttgtttgg acttgctggc attttctttt tgaagtctca attggataaa
    10441 cctgaatttc gtgcacaatt ttcagctgag cagctaaggc tatttgaggt tggcatatca
    10501 ccctttacta tttttatgtc agtgattagc cttggattgg ttgttttgac cactgtgctt
    10561 tgtggcttta acctctcaaa aatcaaacaa ggttccactg tcagctatgt tccttacatt
    10621 atagggattg tgctctatct tattagtatc gtaagccaac tatttagcca aattgagcct
    10681 gtctcaatga tcattgtcct agctgagctt gcgctttacg gctttgcctt ttacaaggct
    10741 aaaaccctta atgaaaaaga caaggacaat ccccaaagca ttgaagaata agcaggccat
    10801 aaaggtatga taacaagact tcctgtctgc cttcaaatat ggctctttgt cagcccacta
    10861 cggttgacaa agagcctttt ttaaccacta aaaaagcaag aggaaaattg ataatgtcct
    10921 cttgcttttt ttgttagttg aatgacaggt ccaacaaaat atctgtcact ttatccttta
    10981 gtccggtcat tgtgactccc aataagcgga ttcctgcctg atgctcctcc aggctatcaa
    11041 aaagctctct agccacctga tcaatgatcc tagcatctct tgttaactca ggtaggctaa
    11101 cccgcttggt caaggtcgta aagtcagcat accgaacctt caaaacaatg atccttccta
    11161 gttttttatt cgcctcaagc aaatcagcga cccgtcttgc atgtttagaa agctctgcct
    11221 taatatcagc ctcctggtag aggagcttag cataggtacg ctcactgctg atggatttgc
    11281 gcatacgatt aggcttgact ggagaatgac taatgcctct ggcctttcga taaagctcat
    11341 agccaaagcg tccaaactga tcaatcaggg tcatctcagg aacacgcaaa agatcctgcc
    11401 cagtgtaaat ccccatctca tgcagccttt caactgttcg cttaccaacg ccatgaaact
    11461 tttcaatcgg aagcttttct aagaatggca gagcatcatc aggaagtact agggtcagac
    11521 catgtggctt ttcaaaatca ctagctagct tggctaaaaa tttgttataa gaaacaccag
    11581 cagagcaggt caactgcagg ctattccaaa tatcatgctg aatcagtctt gcaatcttta
    11641 aggcagactt gatgcccagc ttattggttg tcacatctaa ataagcctca tcaatagaca
    11701 caggctccac ctgatccgta taacgcttga aaatctctct gatatcatag ccaatcctac
    11761 ggtacttagc atgatctcca gagataaaaa tagcctgagg acaacgctcg taggcctcct
    11821 ttgagctcat tgcagagtga atgccaaacc ttcttgcctc gtagttacag gttgatacaa
    11881 cgccccgtcc accactttct ctagggttct tgccgatcac caccggcttg ccctttaatt
    11941 cgggattatc tctttcttcc accgcagcaa aaaaagcatc catgtcaatg tgtataatct
    12001 tgcgtgaggt gtcattaatc agcggaaaaa taagcatagg tccctccctc ctacattata
    12061 ctcctttagg cttttaaagc caaggcagag gattgtatga cagttttcaa ctgtttcagc
    12121 aaactgtaat ataaaagaat cttgtatttg tcaagatttt tgcttgggaa atcgtttccc
    12181 ctatggtaaa cttagattgt aaatgtaaca gattggactt gttactagat tttaaggaga
    12241 aacttatggc aactgttaaa actaacgcag atgtttttga aaaagcttgg gaaggcttta
    12301 agggaactga ctggaaggaa aaagcgagta tatctcgttt tgtacaggct aactatacac
    12361 cttatgacgg tgatgaatca ttcctagcag gtgttactga gcgttcattg cacatcaaaa
    12421 aggtcattga ggagactaaa gctcactacg aagcaacacg cttcccatac gatactcgtc
    12481 caacctcaat tgctgacatt cctgccggat ttattgacaa ggataaggaa ttaatctttg
    12541 gtatccaaaa cgatgagcta ttcaaattga acttcatgcc aaagggtggt atccgtatgg
    12601 cggaaacaac tctgaaggaa aacggctatg agccagatcc tgctgtacat gagattttca
    12661 ctaagcatgt gacaacggtt aatgacggta ttttccgcgc ttacacgtca aacattcgtc
    12721 gtgcgcgcca tgcccacact gtaactggtc tgccagatgc ttactcacgt ggtcgtatca
    12781 tcggtgttta cgcacgtctt gccctctacg gagcagatta cttgatgcaa gaaaaggtca
    12841 acgactggaa tgccatcact gagatcgacg aagaatcaat ccgtcttcgc gaagaaatca
    12901 acctgcaata ccaagcactt ggcgaagtgg ttaagttagg tgatctttac ggtgttgacg
    12961 ttcgtcgtcc tgctgaaaac gtcaaagaag ctatccaatg ggttaacatt gcctttatgg
    13021 ctgtttgccg cgtgatcaat ggtgctgcta cttctcttgg acgtgtccca atcgttcttg
    13081 acatctttgc tgagcgtgac cttgcacgtg gaaccttcac cgaatcagaa attcaagaat
    13141 tcgttgatga ttttgtcctc aagcttcgta ccgttaagtt tgctcgtaca aaggcttatg
    13201 acgctcttta ttcaggtgac ccaaccttca tcacaacctc tatggctggt atgggtaatg
    13261 acggtcgtca ccgcgttaca aagatggact accgcttctt aaacacactt gacaatattg
    13321 gtaactctcc agagccaaac ctaaccgttc tttggactga taagttacca tatgctttcc
    13381 gtcgctactg tatgcacatg agtcacaagc actcttcaat ccaatatgag ggtgtgacaa
    13441 caatggctaa ggacggctac ggtgaaatgt catgtatctc atgctgtgtg tcaccacttg
    13501 acccagaaaa tgaagagcaa cgtcataaca ttcagtactt cggtgctcgt gtgaacgtgc
    13561 ttaaagccct tcttactgga cttaacggtg gttacgatga tgtgcacaag gactacaagg
    13621 tatttgacat cgaccctgtt actgatgatg tccttgactt tgatactgtt aaggctaact
    13681 ttgaaaaatc acttgattgg ttgactgata cttacgtaga tgcgcttaat atcattcact
    13741 acatgactga caagtacaac tacgaagctg ttcaaatggc attcttacca tcacatcaac
    13801 gtgctaacat gggatttggt atctgtggct tcgcaaatac tgttgacacc ctatcagcta
    13861 ttaaatatgc gactgttaag ccaattcgtg acgaagatgg ttacatctat gactacgaaa
    13921 caatcggcga ctacccacgc tggggtgagg acgatcctcg ctcaaacgaa ttagctgagt
    13981 ggttgattga ggcttacact acacgtctac gcagccacaa gctttataag aacgctgaag
    14041 caactgtgtc actgcttacc atcacttcaa acgttgctta ctctaagcaa actggtaact
    14101 ctccggttca ccgcggtgtt tacctcaacg aagatggtac aactaaccta tcacaacttg
    14161 aattcttctc accaggtgct aacccatcta acaaggctaa gggtggctgg ctgcaaaact
    14221 tgaactcact tgcaagcctt gacttctcat atgccgcaga tggtatctca ctaacaactc
    14281 aagtatcacc tcgcgcgctt ggtaagacac atgacgaaca ggttgaaaac cttgttacta
    14341 tccttgatgg ttactttgaa aatggtggtc aacacgttaa cctaaacgtt atggacttaa
    14401 atgacgttta cgataaaatt atggctggtg aagacgttat cgtccgtatc tctggatact
    14461 gtgtcaatac caaatacctt acaccagaac aaaaaactga attaactcaa cgtgtcttcc
    14521 acgaagtgct ttcaatggac gatgccgctg aagctatttc aggaaaataa gctaatctta
    14581 gctagctaag agcctgtctg ttgacaggtt ctttttttat cacacatgca ataggtacag
    14641 ctgtcctcag cagctgaata accagcagag ctggttgaaa ctactagcaa gcctatcatt
    14701 atcattgtga aaatcagacg attaaccttt tcattaaaaa aaaaaaaacg aaactacgga
    14761 gaaaagctga tgaggagctc tttaaggcta tcagtcaaca tgttaaactc ttcttaggaa
    14821 gcgttaacaa taactaactg ctaagctaag caattatcta ttaaggagaa taacaatgaa
    14881 acgactaaaa acactatgct tgttagctac tgctataacc ctaaccctag ctcctatcag
    14941 cacaagccag acaacaacac agaccgtata tgctagtgaa actcatcaaa atctttgtac
    15001 gaacactggt aacggatggt ttaaatgtcc cgatggacat ggagggtgga cttggcattt
    15061 tgacgaaaat cataagtcaa atcagcagtc ctttttggga ggattgttgg gctttgcttt
    15121 gtctctatgg ggagctatta ttagactctt ttaagctcta gcttaactaa tcctcaaaca
    15181 acaaaaataa gctcttagag aactaagctc taagggcttt ttgctgttct gataagtaaa
    15241 aaccaagaga caaggacatc aaaaacaagc aggcctatca gatataccac ctgataggcc
    15301 cacttgtgct ctcattctta tctaggacta tttctgtcaa aggtcctatg aatagcatcc
    15361 cgaagctgtc gtctctcttt gatccacaag gccctatcat ccttgtcata ggttctattg
    15421 gtgagaaaaa tcgctgcctg ctgctccttt ttattgagca tgataaaagg ccctgtatag
    15481 cctgtatgac taatccaatc accctctagg ctccaaccca aagacctggg cttttcctgt
    15541 ctgctatagc tttgaaaaag tctatccgaa aagctttcct tcaggtaatg ctcaataaac
    15601 cgctctaaat ccctgatggt tgaaaaaagc cctgctgagc ctgcatggtt tcccaagacc
    15661 ttagccttgg gatcatgtac ctctccatca agcacccctt tgaccgttgg aactgcttct
    15721 ggccttgggc caaaggaggt ctcagtcatt ccaaagggag taaaaaccat ctcctgaaaa
    15781 agctcatcaa gagactttcc atgaaggtgc tctagcatga agccaagcaa taaaaaattc
    15841 acatctgtgt aatgaaaggt cttatcgtcc ttgacctgaa gctggtgcat cgctgctctt
    15901 aattgctggg cattgagctg atctcgattg ggaatataag ggtcaagtcc actagtatgg
    15961 gtgagtagct gtcgcagtgt aacctccagc ttttgagcgt caggataata atgccttaaa
    16021 ggagtatcaa gagccaaggc accactattg atcatggcta tacagacagt cgctactccg
    16081 acaaccttag agacactggc taaatcataa accaagcctt tggtaacagg tctttgacca
    16141 tcaagggtac cgatataatg ctcctgccaa ccgccacagc gaaaaagggc taagctagcc
    16201 ccatgatata agccttcctg aatctgctgg cttacctttt ctatgacttc taatgtcatt
    16261 tgacaaacca aatttcgatc tgacttgggt ctgaaagaac aagcaccctt gcctttttat
    16321 ctaaataaac ctgacaccct ttgtcctcaa ggtaggtctt tagagcaagc aagtcatagc
    16381 tatctgacac ctgaaattct aaaatctcca aatcccatgt gacatgcggg acaatcgtca
    16441 aatcttgacc agcctcccta ttaaactcaa gcgtgaccgg caggcaatca ccaaaaatag
    16501 actgataaaa agctctggat tgctcgtcat ctaaaacatt taagacaatc agatcaaagc
    16561 taaactgact cagcccccta aagtcagctt ccttgtcaat tgcaggaaca tcatcgacaa
    16621 tgtcaagctc cttgatatcg tcctctgcat ggagtaagaa gcgatctccc tctggtgagg
    16681 tgacttcaaa ggcatagcct ttttttccct tgaaaatcaa atcatagtca acgccatgag
    16741 ctaggagctg ctcaatgtcc ttaggagcag ttgttttgat aacaattgta tttactttct
    16801 tagggccatc tacaacgcgt gttcttgctg ctggagattc ttcaattaca aagcgttctt
    16861 gtccttggcc ccaagatgaa aaaattgata tcgcgttttc ctctgacact agccttaagc
    16921 ctagattttt ttggtaaaag gcaatattaa ggtcgcgatt gttaacacgt aatactgggg
    16981 ttttaaagac aatattgtca aataaagtca tatattcctc ctaatcctct gctattatag
    17041 acaaaattcc aatttttgac aagaaattat atgcttttta accgcctgtc acgcgctacc
    17101 aaggcaatat agcactcaca gccatcacca gacttactag gtccaatctt ccttcgtgcg
    17161 ctctatcaca agcagctttc cttagcgtaa ctcatgcaca tattggtaaa tgcgactttt
    17221 tcaaaatagc acatgaagta cccctttaat ttgacttttc cttaaccaaa agcgagaacc
    17281 ttttttagtt ctcacagtag caatcacact cttgaaatgt gatttcgctc tcctcaataa
    17341 cagatgataa ctgaaattgc ccggattttc ttatccacgc gcaacttcaa aagcacctta
    17401 tcttcagcat tagtaaggat actaccagct tagctcagac cagattcagc tggctcttgc
    17461 tggcaagctt ttatcacaaa aaagaaggcc taagccttct tttttacttg atataaagga
    17521 atttgaatgc tgctactgct gctactgctg ctagcactgg ggcagcaacc ggtacccatg
    17581 agtaccacca ttttgaatcc cccttggctt gtccaaggac tgattttggt aagaaatggt
    17641 gaaccaaacg agggcctaag tcacgcgctg ggttgagcgc tggaccagta ggaccaccaa
    17701 gagaggtcac aagagtcatc accaagaaac caatccccaa gtgagctact gcaagtgagc
    17761 ctgtcacgta aggagagatt tgcgttgcag ctgttgtttg gtcatagcca gcctctacca
    17821 gcttaccaac aagctccaca ccaaagtaat tcttggttaa ggccattgcg ccaaaaaaga
    17881 ggacaaagga accaacaaac tcgttcaaaa agccattaat gtaggctgcc ttacggctgc
    17941 tcttgtcacc atcatcaact gctgaaatcg ttgagaagga tcccaaaata ttgttagggt
    18001 tgtctgtctg cacaaaataa ggcttgtaca ccgcaacaac cactaattgg ccaaacatag
    18061 cccctagcaa ttgagcaaga acatattgta aaacgtgtgc ccaagggaac aagcctgaaa
    18121 ctgccaagcc aaaggtaaaa gctgggttaa tgtgatttcc agaaacgtta ccaaacataa
    18181 gtgccggcat catcacaccg aggccatagc caaaggcaat cacaagccag cctgagcggt
    18241 taccctttgt tccctttaag tcaacattgg caactgctcc atttcccaaa ataatcaaaa
    18301 atgcagtggc aataaactct gtgatgtatt tcacagtcca tgttatttcc atattctcta
    18361 gtttcctcca aatgataagt ataacagata ccattttatc agggatacta gttcttgtaa
    18421 agcctattgt aagatattgc ctgcttaata tgtttacagt gttttttcac aattacggac
    18481 aactaataag tcttttttag catgtcgcag gatatactct gaggtcgatc caatcagcag
    18541 acgctcaaag gtatttaagc cagttgctcc taccatgatc aaatcagcct gctccttttc
    18601 aggtatgtca ctagctaaga gctttttagg gttgcctctt tcgatgattt ttttaatgct
    18661 gctaacgcct ctgcctctag ccattttctc gtaatagcgc aacacctcct tggcatgctc
    18721 ctcttgtgtg tcaaagacat aatcactaac cattgcatca ccctgatagg ccttaacatc
    18781 aataacatga gccagcagta agaccgcatc attgcgaagg gcaacattaa tggccttctc
    18841 aacagctaat tctgattcgt aagagccgtc caccgcagcc agaatccgtt tatatttgct
    18901 tatcatcttt gtctcctttc gttgattagc ctttatcaat agcctttgct tgtgtcttta
    18961 ggaaatacat gactgcgcag gcagctggaa tgagccctgc cagccagaac aattgatgaa
    19021 aggactgcac accagaccca agaagcatat ccttgatgag tcccaacaga taaggtcccg
    19081 cacccaagcc caaatctagc ccaatcatat aagtagacat agcggtatta aagcgatgct
    19141 cctcaacccc cttgatggag gctgcctgtc cgcaggacat aaaggttcca tagccaaagc
    19201 ctatcaaagc acccgaaagc agatagggaa ggctgcttgt cacactacca agcaggaaaa
    19261 gccctagcgc caaaaagaga tagctgggat aaagaaccca ctgctccccc ttaacgtcca
    19321 tcaagcgtcc catagcaggt cgtgtgatcg taatgatcaa ggcatatacc acaaagaaat
    19381 aggctcccac cgtcgtcaaa tgaatgtctg ttgtgtataa tttttgaaag cctagcacag
    19441 aagcataggc aatccccatc aaaaaggcaa tcaaggtgat aaataaggcc tttcgctcaa
    19501 taaagctatc aactgtccag gattttgttt ttgccagctg ctctgagttg agggcaatat
    19561 ctgtcacagg aaaggcaaag gcccctagca caactactgc gatcaacaca ctgcacaaaa
    19621 taataatcat ccgaaaatca atgtgcaaat tatccagcat aaaggtccca acaaaaggac
    19681 caatcgccgc cgctaggctt gttgatagac cataaaaatt aatcccctct ccgcgcttgc
    19741 tagctggaat ataggcagtc acaatggtat tggttgctgt tgagacaaca ccatagccaa
    19801 agccattaaa caagcgcaca aaatacatca tgccaatcgt tggcatgaaa aagtaggcta
    19861 gcgttgttag gagataaaaa atggcgcctc ctcttagcac taagcgtcgg ccaaaaacct
    19921 ccaattgctt gccaaaaatc agtcgagcca gcagggttcc taggatataa atccccgtcg
    19981 ccagacctgc ctcactggtc ttagctccta attccttagt cgcaacaaag gcaatgatca
    20041 ccgtaaacaa gtaatagacc atatacacaa taaaatttaa tactgtgatc cctataaaat
    20101 gcttgttaaa taatttgtct tccactgaaa atgagctcct ccctatttca ttaacatttt
    20161 acaaaaaaat cagataatgc cccatttcaa tggtataata taggtgatac tattaaacga
    20221 cattagcaaa tgctaagcat tgctgcagca acaaattata taatgatacc agaaacacct
    20281 ctaggagaaa agcgtgaacc atcaaatctt acagcgttat attgacagtc ataactttcc
    20341 tattatcgaa aagggctacc acaaatacct gacctttgaa agcttagagg aggattttac
    20401 gtatatccta aaggagggca ttgtcaagca aagcgttctg tcaaaatatg gcatggaatt
    20461 taacctcagg tacgtcacag gccttgagat cacctctgtg cttaatactg gctattccaa
    20521 ggacatgaga gagccctaca atgttcgcat cgaatctgag actgccagct tttataaggt
    20581 tcgtcattcc acctttttaa gggatattag cgaggatatc gagctgcagg gctatgtcaa
    20641 ggacttttat cactaccgcc tccaaaaatc aatgaaaaaa atgcagtgta tgctgacaaa
    20701 tggccgtatc ggcgctatct ctactcagat ttacgattta atgacccttt ttggacgccc
    20761 cttggctaat ggccatatcc ttattgattt tatcatcaca aatgaggagc tgggcaaatt
    20821 ctgtggcatt tcgactgcca gcagtgtcag tcgtctccta aagcagctca aaaaagaggg
    20881 cattattcaa atcaatgacc agcatatcat cattaccaat ttagagaagc taaaggataa
    20941 tattgttttt taacgattta gaaaggacgt cccatgcgct ataatcaatt gtcttacatt
    21001 cccaccagtc tagaaacagc tgtagctgag cttcaggccc tgggctttgc tgtccagcaa
    21061 gagcaagcac ccaaggagaa cttcgctatt ttccttagaa agctattttt tcattttcag
    21121 gataccgatt atcccttgag ccatatgatt gcaagcaagg atctcgacct attgaccttt
    21181 ttaacatctg atgcaacact gacaaaagag gtttttgatt tagtggcctt acaggtcctt
    21241 ggctttattc ctgctgttga ctttaccgat gcacaggact ttatacaaaa gattggcttt
    21301 ccgattgttt ttgacagcca gcaattacta ctcaatttac atcagctgct tgcaacccgg
    21361 cagaagtccg gtgtgacctt gattgatagc cttgttagtc agggcttgct tcctatggat
    21421 aattgctacc actacttcaa cggaaaagcc ctagcaacct ttgataccac cagcctcatt
    21481 cgcgaggtgg tctatgtcga agcgccactt gataccgatc aagacggaca gcttgacctc
    21541 atcaaggtca acattatccg ccccaaggcc agcactgcta tcccaagcat gatgacagcc
    21601 agcccttatc accaagggat taacgagacc gccaacgata aaaagctcca tcgcatggaa
    21661 ggtgagctta gccctaaggc tcctcgtagg attaccgttg agccaactga ttttcagccg
    21721 cttgccacca agccctcaag gcttcctgtc aatgagtgcc aagagacctt cagccatatc
    21781 agctcctaca cactaaatga ttattttcta gcgcgtggct ttgccaatct ctatgtctca
    21841 ggagtgggaa cagcaggctc aactggcttt atgacaagtg gtgactacgc ccagatcgaa
    21901 agctttaagg ctgttatcga ttggctaaat ggcagagcta ctgcttacac gagccacaag
    21961 cgtgactatc aaatcaaggc tgattggtca aatggcttag tcgcaacaac tggaaaatcc
    22021 tatcttggta ccatgtcaac aggactggct acaacaggtg ttgatggctt agcagtcatc
    22081 attgctgaag ctgccatttc ttcttggtac gattattatc gtgaaaatgg gctggtatgc
    22141 agtcctggtg gctacccagg agaggatctc gatgtgctga cagagctcac ctactcgcgt
    22201 aacctgctgc caggtgatta cttacgtcac aacgaccatt atcaacagct gctgagccaa
    22261 caatctcaag ctctcgagcg ccaatcaggc aactacaatc aattttggca tgaccgcaac
    22321 tacctgccac aggctgatcg catcaagtgt gaggtcgtct acacgcatgg cctacaggac
    22381 tggaatgtga agcctagaca ggtctacaat atcttcaatg ccctgcctga tagccttgga
    22441 aagcaccttt tcctacatca tggtgagcat gtctacatgc acaactggca gtcaattgat
    22501 tttcgtgagg ccatgaatgc cctgctctgt caaaaaatgc taggacaaaa taatggcttt
    22561 accctaccaa caatcatctg gcaggataac caaaaagaac aaacctggaa agagctaaca
    22621 gcctttggcg gtcacagcaa gcgtcagatt gccctaggcg atgatcatgt cttaattgac
    22681 aatcactatg gcgaagagga ctttaagcgc tatagcaagg attttcgtgc ctttaaagct
    22741 gagctttttg aaggcaaggc aaatcaagca gtcattgata ttctgttaga agaggatcta
    22801 ccaatcaacg ggcaagcctg ccttaagctt aagctaaaat caagtgaaaa caaggggatt
    22861 ttggctgcac agctcctaga ttatggcaag aaaaaacgct ttgctgatat acctgctatt
    22921 cttgagctag acagcattga caacgggcag cagtttgcac gtgaagcgct caaggagctt
    22981 cccttcaagg acagcccata ccgcgttgtc accaagggtg tcctaaacct acagcaccgc
    23041 agcgacctat tgaccattga ggatattcca aatgaccaat ggatgaccat caccttccac
    23101 ttgcagccaa ccatctatca tatggccaag ggagacaccc taagagtcgt tctttacacg
    23161 actgattttg agcatacaat ccgcgacaat agcaactatg ccctaaccct agatttggag
    23221 caatcctatc tcctaatccc tactgatgag gaggaataaa tcaaagcgca tcaaaaaagc
    23281 ctgagatcac aatgagctgc accccaatcg ttagatcctt tgtctaactg ttggagtaca
    23341 gctcaaagct ctaggctttt ttaactattt tgaaaccttt ttaccagcct cagcaccaga
    23401 atgcaggctg tagacggact cgatatgaat caagcctgct gcctttggtg cgcccatctt
    23461 gccttctgcc cattccttgg cagcctcaaa gacaggaccc tctgtaatga tttccgcacg
    23521 ccctacaaag cgataaccac gcaattgctc gcgattgaca taagcgacct caattttacc
    23581 attagcctga atattagagc aggtttggcc gccagtattt tcattataaa ccaaggtttc
    23641 atcgtctaac agtctcatcg aacgcttagg gccaatatta ggattaccct cattatctac
    23701 agttactacc attgctaatt gctcagcaat catttctttc atttcttctg ttaacatata
    23761 atctcctctt aatcgtttct atagtcagct gactacgctt tgattatagc acagttaagc
    23821 agaaaagccg acaaaaatag gttagcttaa aaaagtttta cagtttactt aagattagaa
    23881 tgattctcgc tatctagcca tcacccttga tcacagtaaa aaggcgatta gcaagcaagc
    23941 actctttatt tcataaaatc cgaatcgtcg cccaaaaaaa atatcatcaa ctgatatggt
    24001 caatgcctct gcaatacctc ttaatttttc atacttagct cgcctaagct tttgcacatc
    24061 cttttcatat ctggctagtg tcctaacaga aatcccagtt aacgctgaca gttccttttg
    24121 ggtctttttt tgagcaatcc tcaattcctt taacgttgct tttgacaata ttttccctcc
    24181 gcctctcatc tcaggtaata ttaatgacag atgacaagtt tattatagac ttcggttttt
    24241 atgaagtcaa gtcttttatc gcactttccc cacttctttt tctaaatctt ttgatttagc
    24301 ttgatttgtg gtatcatatc ctatatagaa ataaaggaga atggaaatgt ccgaaaagaa
    24361 aacatttttt gcaactaatt taaaatatct tcggctaaaa aagaatatgg aacaattaga
    24421 acttgctaac cttttaggac gaaaaagctc ttcctcaatc agcgaatgag aaagaggaaa
    24481 gtacactcca aaatctggtc tcctgagtga cattgctgcc atctttgatg tcagcctgac
    24541 agacctcatg gaaaaggatt taacactgga aaataaggga gtgacttatc agcttcccca
    24601 aagagattta gtaatgattt cagagcagct atctgaaaac aattataaca aatggctgga
    24661 ttttggtcag gatctcttat ctcatcagga taaagaagaa aatcacaagc caagcaaata
    24721 aagagcctca cacgtcttat tctcatcaag tttcgaaaaa tcacctacca ctcaagcaca
    24781 caaaaagcct tggcagggct tctaagcata agaaagctgt atcatatcaa tacctcaggg
    24841 accatgatat gatacagctt tttgtatctc acttttagac aaggtagcca cataaagctt
    24901 gcagatgacc tacctctgta ttagctacca caaccaacag ctagctagac tggcaggccc
    24961 tctataagcc tcagcggatt atctaagcac tcccaacagc tccaacaaaa taaagacata
    25021 accaatacca ttatttaaga tatgggctac tgttgaaaaa tagatattct tcttccaaac
    25081 ataaactaag ccgagcaaaa gtcccagtcc accatacaca acgatggaag atagctcgct
    25141 gaaggaatag atatgaacca agccaaatag caatgatgat cccaacaatc gagccagcag
    25201 catacctgtg cctgattggc cctcaccgat taaaatcttg cggaaaataa gctcctcatt
    25261 gaagggacca ataatactca ccaccagaat aaagatcact gtctcgaagc cctcactagc
    25321 attatagcga ttagctaaaa cagctgcatt gctgctctct tctaaaggaa ggctactgag
    25381 caaaatattt gcaacataaa gcactgcaaa aatgaccaag acccacaagg tatttttgac
    25441 ccattttgtt gaaaactgcc gccagtccct ctgataatct gctcgataaa gccaacagat
    25501 cccaagtgca aaaatcagca gatgtctccc gtaaaataaa aaggtattca ataaaggcgg
    25561 aagctcaatc acattgctaa cttgtctata aagatacaca gcaatgatat atagcatgac
    25621 cagtacagct gcacgatgac gtttgatggt atccaattac tcttcctcaa ttctaataat
    25681 tgtcagatta gctaggctat attgccatca gctaatcttg atcttaaatg tgactaattt
    25741 acaagcactc aacttttgaa tcggtaaagc tgacagacag ccctacccta gcttcaataa
    25801 agctatcttc caatagtcct tgcgctcatc agaactgtca aaggcctgac ccagctgagt
    25861 caacagactt atccagtcaa catcacacag aacaagacca tcttaccata tccctgccaa
    25921 ctataaaagc ccctaacctg acctatttga ctactaacag caaaaaagca gcttaaaaac
    25981 accaatcaga cgccaccaag gactcttgat cagcgcagct cgcacagaca cctgaaaaat
    26041 gacagacaag cctcttaaaa gcacctcagc aagctgagcc aacccttcac agaatagaca
    26101 aacaacaaga gctaagtcaa gacctcaagc tagcagatta caggcagaga cgcttgcaag
    26161 gcttacccag caaaaagcaa cagactgata aaggattcac accacacagc cacaagtcaa
    26221 gcagctagcc caaacaaagc actgctcacc aaatcctact atgctttctg gtagccctta
    26281 tccattcaaa atcgtatcca aggcttcttg atattgcttg tctcgcaatt ctctgatcac
    26341 ctgtgataaa tactctgcct gatacatcac aaagtcaaaa ttgaaatcca gaattttggt
    26401 gttctcattc aatgacagcc tctcctcgat aaaagcagtc atctcagctg ttgtcacaat
    26461 caagtcaaaa tcagttctcc aaggcaattc agcctctgac aaaatattaa aacgatagac
    26521 ctttgcaaca caaggactca cctgttgcat gaccaagcta tataaaatat caatgttttt
    26581 cttgttgatt tcgatcactg ctatggctaa aggtggcaga ccttctctaa caagctgttc
    26641 cagtcgcgtg caaagcaaat gcaaattaga gcctgtcagc cgaccaacac cagaaacccg
    26701 ctctgcccag ctattaatca tcagctcgat acgattggcc aagagcttac tgccttgata
    26761 ttcctccgca taataatatt tttgcgggat aaagagcgac aaatcaaaca aggtcttacg
    26821 aaaataagga atcaaggtct gaatacaagc cttgtcaaag gcgatatagt ggccaaacaa
    26881 ttgacgcagc tcacccagca gctcttggta agcaggatcc tcctgaatga tcgtcaataa
    26941 ggccgaagaa tcctcctcag accattgtgt gatcgaaaaa gagttgttaa ccgtcaaata
    27001 aacgagaaaa atataatcaa tctcgctact gggaaagtcc atatcaagca acaatttccc
    27061 ctcacgcttg aaaaagtcct ccaaataccc ataaagcgcc aaagacttta agcgtttaaa
    27121 aatcccctcc tgaggaatcg caacgtcaaa ctctccacgc ttccaagata gcgacaagag
    27181 cacatcaaaa aagcgaaact tcttatccag taacgggtga ggcgtttgtt gctttttgat
    27241 cgaaaagata aagtcatgca caatatccag atcatggtca gtcagctcat agatgacaat
    27301 cccgtactta tcatgcaata aagcaatcaa atagcggata cgccactcct caccaacaac
    27361 actattatcc tctaaggcca agccgcactc ctcaacaaag ggcttcatgt gctgaatcag
    27421 ccgataagct gacggtgtgg aaataaaatg ctccctagca aagcctgaga cagatttgac
    27481 cttatagcaa ggtgccttga tcaagagaaa tttaagaatg tgcagccgta ccgattggcg
    27541 gtaaatcgtc ttcaaaaacg gtttgcccct tttcaaaacg gtgcagcgga caatggtgct
    27601 atcccactca aaggcgatat ctccttggaa aagctcctct aattggtgga tatagcgctt
    27661 tatgttagct aggctaaagc ccgtcttttg ctgaatggcg tggaaactga tccttttttt
    27721 accaagtagt atggtcagca gcaaagcctg atgattaatc actggttcca aatactcttc
    27781 aagcaaaaca ctttctcctc cttaaaccat ttcgttagcg tcattatcat aacaattttt
    27841 accaaaaaag tgatgaaaaa tatttaatat caggacgatt tttctgatag cctttattat
    27901 aacacaaaag ctcaaggcag gtaaaacgat aaagaaatca acttaaaact atgacacagt
    27961 ctcatctcat atgatatagt tattcaggtt tcctaatgga aaacatatta acaacttaat
    28021 aatggagaga agaaagttga aaacaaaatc atttagaaag gtactgacaa cgtcagctac
    28081 ctgtattgtg ctggcaacaa gctttgccgg aggaacccta agagtctggg cagagcagct
    28141 ttattatggg tggaatgatg gaacgagaca aagttcgcca tattttttgt acgtatcgcc
    28201 taaaaatgct ccaaagcgtg aattaaaaga cgagtatgtt gtttattgct ttaacaaaaa
    28261 attgtattgg ccagatcaat gggaatctat atacagcaat tttaatgaca tcagatctcc
    28321 atataacgat ttacctgtat atgagaaaaa actaggatat gatggtatat ttaaacaata
    28381 tgctccagat tacaaaaaag atattagtga tatcgcaagt gctttggtgg cagttttaag
    28441 taatggatac cccactaaca agtcacaact atcaactagc taccatttaa ataatgattc
    28501 ttctagaaaa gttactcaat tagccatttg gtattttagt gatagtttaa caaaagaata
    28561 ccttaaagat acgggtggtt ataacttaaa cgatatggaa aaaaaagctt tagatttttt
    28621 aatcagtaaa ggagaggatt ctaagcttaa atcagagcag agtaattact cattggatat
    28681 ttatgtttat caaagtggcg ggcatgacca tatgaaagat taccaaaatc ttctcggctc
    28741 taccttaatt cctaaagaac cgctaaagcc tcagctaggt ggttttagtg gacataatgg
    28801 aaatggatta agcggccttg aaggaggatc atcaggttca caagaaacta atgaagatgg
    28861 taagaaagga cttataggtt tccatggagg actctcagga agcgagggca aacgagatcc
    28921 tttccaggat tgaagggtga ggctggtgca cctgatacac ctcaaaagcc taatgaccca
    28981 ttgcaaagtc ttgaaggtgg taactctcct atcgtagaac aaaactatgg tagtactgag
    29041 ggatatcatg gtcaatctgg cattcttgag gaaaccgaag acactaaccc acctggtatc
    29101 attttaggtg gctcaggaaa tgtcgaaacg agatcctcat ctgatggggc ttggcggtgg
    29161 tctagctggc gaatcaggag aaacgacacc taaaccagga cagactggtg gtcatggacc
    29221 aatcatcgag acaacagagg acacacaaaa aggcatgtct gggcaatctg gcggcactat
    29281 cgagtcagaa aacaccaaaa agcctgaggt catgattggt gggcagggac aaaccatcga
    29341 aacaacagag gacacacaaa aaggcatgtc tgggcaatct ggcggtacta tcgagtcaga
    29401 agacactaaa aaacctgagg tcatgattgg tgggcaggga caaaccatcg aaacaacaga
    29461 ggacacacaa aaaggcatgt ctgggcaatc tggcggtact atcgagtcag aagacactaa
    29521 aaaacctgag gtcatgattg gcggtcaggg acaaatcatc gacttctctg aaaacacgca
    29581 atcaggtatg tctggacagt ctggagacac tacggtcatt gaggatacca agaagtctga
    29641 gataatcatt ggtgggcaag gacaaatcat cgacttctct gaggatactc agccgggtat
    29701 gtctgggcaa tctggaggca ccacaattgt cgaagacacc aagaagccga cacctaagcc
    29761 taaacctgca cctgcgccaa ttgttaatga cgaaaaacct aacaaaggca ctcagctccc
    29821 acagacaaat gatatgaagc aactcaccct aagcatcatc ggtgcaatgt caatgctgct
    29881 tgtcctatgt ctgtctctat tcaagcgacc atctaaaaaa gactaagcaa cactgacaag
    29941 tgatcattat tgtacggacg tttacaggcg ggctttctgc cctcttaaaa caccgtacaa
    30001 caacaaaacg gtctaaatag aaatatccct caagggttag acaatcgctc tagcccttgg
    30061 ggcttttttt gatacttata atagaagaga gcaagcagtg acactttctt tttgccctat
    30121 atctgctaac actagcggta tgtgcagtta ccataggcta tcaactcgtc gtgcaactct
    30181 agagaaaagc tgatacaaaa aacaagcacc agccttgctg ctgatgcttg ctccggactt
    30241 actgataagc ctttgtgatg tcctagcttt ataaccatat gcctattacc taaaggtcta
    30301 gtctcctaat ggtgggctgg ctggtaaaag caaggagaaa cagctcccct ttccaagctg
    30361 gctctcaaca gcaatatccc cacctagttg gcgagctaac tgcctagcaa tagagagccc
    30421 cagcccatga ccaccagtct tcatattgcg agaggcctca acacgataca ggcgcttgaa
    30481 aatcaaaggc aggtcctctt ttttgatccc ttgcccctga tcaataacat caatgcgaat
    30541 ggactgctcc tgttgataag catgaatcgt caaagccgta ttagcctttg aatatttaag
    30601 cgcattgctg actaaattca gcataatccg agacaaagca tcatatcggc tgctgatctt
    30661 aaccacctct tttgccacct caatatgaac ggagcgtttt tcctgctcta aggtcaattg
    30721 aaattcggat agcatgtcaa tcaatagctt ttcaagatag atgatttgaa gctgctgctt
    30781 gtcgtcttgc ttttgatcat ttaagctgac catatgcaat tcttcaacta attgattcaa
    30841 acggttggtc tgtcgtgaga tggtgtttag atagtgcctt tcctcttccc ttggaataac
    30901 gccatctaaa atcccctcta cagttgcttg aatagaggtc aagggtgtct taatatcgtg
    30961 cgacagctga gcaatcatca tggatttctc atgctcactc tcactcaatg actcaaagct
    31021 gacctttagc tctgaggaca tctgattaaa ggcttcctct agatctttaa actccaaagg
    31081 acacttgatg agctgaccac tatcaaagtt tctttcagaa atagcctgta tctttttctt
    31141 tagcctttta agcgatgaaa aaacattact caaaaggatc atattcacaa ttcctccggc
    31201 tactgaagca attagagcta ttactaaaat atatgaaata tcctcaatgg taatgagcat
    31261 ttggtttaac ccaacaatca ggcctgcaat agtaatcagc atagacatta aatagccaat
    31321 gacaatgtac gttcttaatc gcatgctacc cctctaattt ataacctagt ccccaaaccg
    31381 ttttaatggt tggtgtttgc tcggtactgt attttgccaa gtcattgcgt agggaatgaa
    31441 tgtgaacatt taaggtattg gtatcatcta aatactcctc ctccca
//
LOCUS       DARYMD010000025        31131 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYMD010000025 DARYMD010000000
VERSION     DARYMD010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31131
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TU818_001053"
     CDS             complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TU818_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL0923876.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDEIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
     gene            complement(1584..2021)
                     /locus_tag="TU818_001054"
     CDS             complement(1584..2021)
                     /locus_tag="TU818_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL0923877.1"
                     /translation="MALSKLSSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTIKFADDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCATLAWHALKQAIEKSDEF"
     gene            complement(2008..3234)
                     /locus_tag="TU818_001055"
     CDS             complement(2008..3234)
                     /locus_tag="TU818_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL0923878.1"
                     /translation="MFDPNQIKADFKLLDQYVNDEALVYLDNAATTQKPQAVLEAMQA
                     YYQKDNANVHRGVHTLAERATRQYEASRQKVADFIGAKSSKEVIFTRGTTSSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSITHVSNVLGCVNPIQEIARLAHARGAYFVVDAAQSVPHMAIDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPDRSDERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TU818_001056"
     CDS             complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TU818_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL0923879.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTALGTVPDFMALGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALDEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDG
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDHAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIVTALDDKLARR"
     gene            complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TU818_001057"
     CDS             complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TU818_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL0923880.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDRDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALAIRLEKEGYAGIAEELGIDYKEEV"
     gene            complement(5505..6662)
                     /locus_tag="TU818_001058"
     CDS             complement(5505..6662)
                     /locus_tag="TU818_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL0923881.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTITGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGV
                     LLILGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TU818_001059"
     CDS             complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TU818_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL0923882.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELGLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
                     HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            complement(7553..8392)
                     /locus_tag="TU818_001060"
     CDS             complement(7553..8392)
                     /locus_tag="TU818_001060"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL0923883.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFK
                     SLF"
     gene            8708..10276
                     /locus_tag="TU818_001061"
     CDS             8708..10276
                     /locus_tag="TU818_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL0923884.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            10269..11009
                     /locus_tag="TU818_001062"
     CDS             10269..11009
                     /locus_tag="TU818_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0923885.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            11357..11473
                     /locus_tag="TU818_001063"
     CDS             11357..11473
                     /locus_tag="TU818_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL0923886.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(11997..12887)
                     /locus_tag="TU818_001064"
     CDS             complement(11997..12887)
                     /locus_tag="TU818_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL0923887.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTLNGVDDIRTQVLSALKTR"
     gene            complement(13150..14814)
                     /locus_tag="TU818_001065"
     CDS             complement(13150..14814)
                     /locus_tag="TU818_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL0923888.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            complement(14814..15179)
                     /locus_tag="TU818_001066"
     CDS             complement(14814..15179)
                     /locus_tag="TU818_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0923889.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            complement(15331..15519)
                     /locus_tag="TU818_001067"
     CDS             complement(15331..15519)
                     /locus_tag="TU818_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL0923890.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(15979..16344)
                     /locus_tag="TU818_001068"
     CDS             complement(15979..16344)
                     /locus_tag="TU818_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923891.1"
                     /translation="MADLSISKKSLLKGLGLLSVCLGLAVGTSRTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIKKIKDSDLDGFIMGNYIDTINSHVFLYKLLHLEEYI
                     DFLIAQFDHFTPEQLEKRD"
     gene            complement(16934..17815)
                     /locus_tag="TU818_001069"
     CDS             complement(16934..17815)
                     /locus_tag="TU818_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL0923892.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            complement(18018..18103)
                     /locus_tag="TU818_001070"
     tRNA            complement(18018..18103)
                     /locus_tag="TU818_001070"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18067..18069),aa:Leu,seq:aag)
     gene            complement(18158..19084)
                     /locus_tag="TU818_001071"
     CDS             complement(18158..19084)
                     /locus_tag="TU818_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL0923893.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPDNPLYPAELAFDSLTREKRSITNRGRQQVAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKGSRI
                     SLFGLSMGAATVMMASGEQLPSQVVNIVEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            complement(19444..21057)
                     /locus_tag="TU818_001072"
     CDS             complement(19444..21057)
                     /locus_tag="TU818_001072"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL0923894.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDRVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKKLLGQADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKAGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            complement(21331..21897)
                     /locus_tag="TU818_001073"
     CDS             complement(21331..21897)
                     /locus_tag="TU818_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL0923895.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            complement(22164..23447)
                     /locus_tag="TU818_001074"
     CDS             complement(22164..23447)
                     /locus_tag="TU818_001074"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL0923896.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFDQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKCQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEEAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVATVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            complement(23796..25205)
                     /locus_tag="TU818_001075"
     CDS             complement(23796..25205)
                     /locus_tag="TU818_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL0923897.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLAPLAPANLASAQEVQSD
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIEGAGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAQEADKYGINIIVDAVLNHTTSEIKAVSPKITA
                     IDNWTHGNDKIVNFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEHNSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYGKL
                     IRKVLGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLGWG
                     IIAARNEGAPLFFSRPRGGGGQNGRFPGESQIGDAGSDLFKDPTIVAINQFRNRMNGQ
                     SEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKDFSSTTTLADGDYKDAVTGTVYHVS
                     NHNITGHLAKKSVAVLLPA"
     gene            25656..26495
                     /locus_tag="TU818_001076"
     CDS             25656..26495
                     /locus_tag="TU818_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL0923898.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTAL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVFYFLLIYWILSLLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTVTIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNKREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYYSFYKLYQEALLREGIKLPTASAIS
                     PLA"
     gene            complement(26591..27151)
                     /locus_tag="TU818_001077"
     CDS             complement(26591..27151)
                     /locus_tag="TU818_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL0923899.1"
                     /translation="MNLKVLREEARSILLDIVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKLILEELSFRGIHLAVQGCEHINRALVLEESVAEEYRLEIVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(27164..27637)
                     /locus_tag="TU818_001078"
     CDS             complement(27164..27637)
                     /locus_tag="TU818_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0923900.1"
                     /translation="MKQTRELALVSILTALTVVLGRFVSIATPTGFLSLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLPGRHRFLGVGLAS
                     VIMVGLYFLAAIPMYGMGAAISEISGNAAQNTLGIGVGYLLYLGVKKQLVKVSDD"
     gene            complement(27643..28392)
                     /locus_tag="TU818_001079"
     CDS             complement(27643..28392)
                     /locus_tag="TU818_001079"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL0923901.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLAKQNSGAGCSFAAAIAAYL
                     AKGYSPLRAVEQAKDLVFEAIQQSNDYGVVL"
     gene            complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TU818_001080"
     CDS             complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TU818_001080"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL0923902.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            29318..30682
                     /locus_tag="TU818_001081"
     CDS             29318..30682
                     /locus_tag="TU818_001081"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL0923903.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLTASYLHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
BASE COUNT         9264 a         7451 c         5667 g         8749 t
ORIGIN      
        1 gccaagaagt cttttttatg ccttaggtat ttaaaaacta acctcttggg ttagtaccta
       61 tgtcttttaa aaagcctatc catcaggtca ccctaatgga taaggtcaat gtagctgctt
      121 cttgactagc caactgatcc ttccatttca taggcgatca agcgattcaa ttcaacagca
      181 tactccattg gtaattcctt ggtaaagggc tcaacaaacc ccatgacaat catttcagta
      241 gcttcgctct ctgacagtcc ccgactcatc aggtaataga gctgctcctc tgaaatcttt
      301 gaaacttttg cttcatgctc aagagctacc tgagagttgt gaatttcatt gaaggggata
      361 gtatctgatt ttgagatgtc gtccatcagg attgtatcac attcgatatg agagactgat
      421 ttttttgaca gcttgttaaa ggtaacctga cctcgatagt caaccttacc accacttttt
      481 gcaatagatt ttgacacaat agacgatgag gtgtgaggcg cattatgcac catcttagct
      541 cctgtatcct gatgctgacc agtattagca aaggcaatgg agagcatggt gccacgcgca
      601 cctggaccat caaggtaaac tgaagggtat ttcatggttg ttttagcacc cagattacca
      661 tcaatccact caaccgttgc gtccttgaga gcacgcgctc gcttggtcac caaattatag
      721 acattgtcag accaattttg aattgttgta tagcgcatgt aagcaccatc taaagcaaag
      781 atttcaacaa tagcagcgtg caagctgttg cttgaatagg taggtgctgt acagccctcc
      841 acataatgca cactagcgcc ctcatcaaca ataattaggg tacgctcaaa ctgaccagtg
      901 tgttcattat tgatgcggaa ataggtttgc aaaggaatgt ctaccttgac cccctttggc
      961 acataaataa aggtccctcc tgaccaaaca gcagaattca aggcggctaa tttgttgtca
     1021 gttgggggta ccagcttagc aaaatactgc ttaaatagct caggatattc ctttaaggca
     1081 gaatccgtat ccgtaaagat aatgcccagc ttttcaaact cagccttcat gttgtggtaa
     1141 accacctcag actcatattg tgctgaggcg cccgccagat aagctcgctc tgcctctgga
     1201 atgccgatgc gctcaaaggt ttccttgatt ttatctggaa catcatccca tgaacgagcc
     1261 ggcttatcag atggcttttg ataatagata atctcatcaa aatcaatatc tgaaaggtct
     1321 gcgccccagg tttgcatggg cattttatga aaggcttcaa gtgattttag gcgaaattcc
     1381 agcatccact ctggttcatc tttagcagct gataattctc tcacaactgc ttcatttagg
     1441 cccttacctg ttgagtagat aggctcaaca tcgtcatgaa agccaaattg ataatcacct
     1501 aaatcaattg gctggggggc tactgtttca tttatatcag acattttcta ttttccttta
     1561 tacgttacta aatgagagag gacttaaaac tcatcgcttt tttcaatagc ctgcttgaga
     1621 gcatgccaag ccagagttgc gcacttgata cgctgtggaa agttggcaac cccagctaat
     1681 agctcagctt cacccaagag agcctgattg ctatcgtcat ttccctgaac catatttgaa
     1741 aaaatgtcag ctagggccaa cgcttcttcc tttgtctttc caaggacagc atctgtcatc
     1801 atactagacg aagcagtcga aatcgtgcag ccatccccgg caaaggcaat atcctcaatc
     1861 ctgtcatcag caaatttgat agtaagggaa atcacatctc cacaggtagg attatgaagc
     1921 tggactgcct ctacaccctc aagctggcca tgatgatgcg ggtgtcttga atgatcagcc
     1981 acaacagcca tatataagct gcttaactta gaaagtgcca ttaaaaaact cctttgcttt
     2041 taaaatagct tctatcaagc gatcgcaatc ctccctcgta ttatagagat aaaagctagc
     2101 acgaactgtt gaatgcagtc ccaagtactt atgcaaaggc tgagcacaat gatgtcctgc
     2161 tctaactgca acgccctcat aatctaaagc cgttgcaaga tcatgcgggt gtaagccatc
     2221 tatattaaag gcaaggacgc ctgagcgttc atctgatcgg tcaggaccat ataccgtcaa
     2281 gccagcaata gcctgcagcc ttggcaaggt ataagcaact aaatcagcct catgagcatg
     2341 aacctgatcc attcctatag cctccaaata tgaaatagca gctccaagac caatagcacc
     2401 agcaatatgg ggggttcctg cctcaagctt ccaaggcaag ggcttccaag tcgcctcctg
     2461 ctcataaaca aaatcaatca tttcgccacc aaattcaact gggttcattt ggttaaggag
     2521 agcctccttg ccatacaata caccaatgcc agtcggtccc agcaacttat ggcctgaaaa
     2581 ggcaaggaaa tcacaatcta actcctgcac atcaatagcc atgtgcggta ctgactgcgc
     2641 agcgtcaacc acaaaatagg caccccgagc atgagcaagc cttgcaatct cctgaatcgg
     2701 attaacacag cctaacacgt tagagacatg ggtgatactg acaaatttgg tgctagcacc
     2761 caattttgat tgcagatcat tcatgtctag cttgcctttc ttaagataag catagacaag
     2821 ccttgcccct gttttttgac aaacctgctg ccaaggaagg atatttgcat ggtgctccat
     2881 aatcgaaatc agcacctcat cacctggctt taagacctgc tcagcaaatt ttccaaccca
     2941 atttaagctg cttgtcgtcc ctcttgtgaa aatcacttcc ttgcttgact tagccccaat
     3001 aaagtcagca accttttgac gactagcctc atactgtctt gttgctcttt ctgccagggt
     3061 atggacacct ctatgaacat tggcattatc cttttgataa taggcctgca tggcctctaa
     3121 cactgcctgt ggcttttgtg ttgtcgccgc attatctaag taaacaagag cctcatcatt
     3181 tacatattgg tcaagtagtt taaagtctgc tttgatttga ttaggatcaa acaatgataa
     3241 ctcctttctt tgactagtaa ctaacgacgt gccagcttat catctaaggc agtaacaata
     3301 tcctgacgaa ccgacggcac agggatttct gccactaccg cacctagaaa acctcgaata
     3361 acaagacgct cagcagtctc ttggtctagt cctctactca ttaaataata catgtcctca
     3421 ggatccacct gaccgataga ggcggcatgg cctgctgtta cctcattttc atcaatcagg
     3481 agaataggat tggcatcaga gcgagcctga tctgacagca ttaggacacg actttcttgt
     3541 tgggcatcag caccctttgc tcccttaatg atatgaccga tagcattaaa tgtcaatgtc
     3601 ccgcgctcca agataacccc atgctgtaaa atatgcccaa ccgtatgttt tccataattg
     3661 gttactcggg tatcaatccc ctgaacttga cgaccacttg aagcagcaac caccttcaca
     3721 tcagcctgtg agccttgacc gatcaaatca ctatcaaagt cagcaatgac attgccctca
     3781 ttcatcagag caagcgccca atcaatagtc gcagcatgat ctaagcggcc tctgcgactg
     3841 atataggctg tcacctgatc acccaggcga tcaatcgccg aaaacttaat ctgacttccc
     3901 gcctgagcaa tgacctcaac actaatattg gcactagctg cttgggtctt gtctcctata
     3961 gactcaaagc gctcaaggta ggtcagctta ctttctttac ctgcaatgat gagcacatgc
     4021 ttgttaaagg ggacatcact atcaccatct tgcaagaaga tcccttcaat tggctgctca
     4081 atctcaacat gatctggaac atatagcaca gccgcactgt taaaataagc cgtatgatag
     4141 gccgccagtc tatgctcatc aaaggctaag gcagaaccaa aatgagcctc aagctgctcg
     4201 ggaatctcat ctagagctgt agcaaggtct gtaaaaacaa ctcccttttc gatcaattcc
     4261 ataggaagct gctcaagaac cgtctgtgtt ccgacctgaa ccagcttagg attatcaccc
     4321 aaggccataa aatctggaac agttcctaaa gcagtgcttt ctgtcaggct accatcacca
     4381 aagttccaac ggtgaaattt aacccgttca atagtaggca gctctaaatg tggcatcaca
     4441 tcaaaggcct ttaagcgcag ctcttgcagc caagtaggct cagcatgcgc ttgagaaaag
     4501 gccaatatct tttcttttgt catctatcct tccttttttc tggtaagctt ttcaatcatc
     4561 agcaaacata ctaatcagca cagctatggc gaagccttag acagccttgc agcttagacc
     4621 tcttctttat agtcaatgcc tagctcctca gcaatgcctg catagccttc tttttcgagt
     4681 cgtatagcaa gtgcagcatc ccctgatagg actatccgac catccatcat gacatgcacc
     4741 aagtccggag tgatgtaatt aagcaagcgc tggtaatggg taataatcat cgcaccaaat
     4801 gcctgaccac gcatctcatt aacccctttt gacaccacct ttagggcatc aatatcaagc
     4861 cctgagtcaa tctcatctaa cagcgcaaac ttaggctcta gcatgagcaa ttgcagaatt
     4921 tcatttcttt ttttctcacc gccagaaaag ccttcattga ggtagcgctc tgccatttcc
     4981 tccttcatgc caagcagggc catcttctca tctagcttgg taatgaagtc acgaacagaa
     5041 atcttatccc tgtcctcttt ccctgcattc atagcggctc gcataaattc ggcattggta
     5101 atccctggaa tctcagacgg gtattgcatc gctagaaaaa gtcccagtct agcacgctca
     5161 tcaacctcta gctccagaat attgacacca tctagtaaaa tctcaccctc tgtcacttga
     5221 tagttgggat tgcccataat cgctgctgac agtgttgatt ttcctgttcc atttggcccc
     5281 atgatagcag caatttcacc tgtccttagg gttagattga ccccctttaa aatctcttta
     5341 tcctctatcg aaacatgcaa attgttgatt tcaagaattg acattgtata cctcatcatt
     5401 tctattaggc tctttcagta tcttctttcc tgaaaatagc ctaatgcttt cattatcttc
     5461 attataacaa aaaaagcctc agcaggcttt ttacttgtct gaaatcattt cctttgcttc
     5521 cattttgaaa gcgtcgtctg acggtaatcg ctattaccga taaacttcaa gaggttgaat
     5581 aggggcgttc gtttttctcc ccagatttca ataccttcaa taaagacctc tagggcaaat
     5641 aagagtccca agataagcaa gaccccacca atacgactag agacattcaa caaaagagag
     5701 atcaaggaaa agagcatagc aataccgtaa acaaccagca ctgcaccgcg atgtgtaaac
     5761 cccattgaca agagacggtg atgcaggtgc atcttatcag gctcgtaaaa tttctttcca
     5821 gacaggcttc gacgaataat cgccacaatc gtatccataa ttggaacacc taaaataata
     5881 accggtgtaa caacggctac cgcagttgca tttttcaagc cctgcaatga taacacacca
     5941 atcataaagc cgataaaaag cgctcccgta tccccaagat aaataatagc cgggtgatag
     6001 ttatagggaa aaaagccagc aatagatgca atcaggatta aaatcgtcag ggttaaaaag
     6061 aaatttgtca atggcaaaaa gaaataagct acaatagcca ttgttactaa gctaataatc
     6121 gaaacaccac tgactagacc atctaagcca tcaataagat taatcgcatt ggtaattgag
     6181 ataatccaaa gaacggttaa aaagaaggtc aagaaaggat caaaagccag caagggtcca
     6241 ccaaaaggaa tcttaaagct atcaaattta aagtcagtaa aggcccagac aataatggca
     6301 ccaatgacaa ttcccagcat tttcagctta ggacttagct catacacatc gtctataaag
     6361 cctgttatgg taaccaccaa gcctcctaag acaactggca aaatatactg aaaataggtt
     6421 tgcccgccaa tatgagcacc atttgatgcc agaggcatca gtaccagact cgcaatcaca
     6481 aaggaagtaa agatagccaa gcctccacta gtcggcatgg gaaccttatt aatccgtcta
     6541 gcatttggag tatctaccac accgactcta atgcttagaa aacgtacaat tggcgttaat
     6601 aaaagtgaca tcagcaaggc accaattaaa accaagacat catctatcgt gaacgaaatc
     6661 atcataccct accccaacct gattttttgc agctcctcaa cagcaccatc aaaaatgagc
     6721 tgacaaccat gctcctgcaa ataagctctt gtttttgttc caggactagc atgctcaatc
     6781 aatctggcat acatcacgtt ggcaaagtag gcaggcttgt tttgcacatc aagtaaaatc
     6841 gtcatgtgat aatgacgagg acccttatac aattcagaag cctcgatcgg aaaatcaatc
     6901 accttagcaa agcaaacagc gtctcgaaca gaagcaaaat caagaacata gtgaacataa
     6961 tcaagtggct ctgtcggctc atcaagctca gcagcttcct tactatctgc ttgctcagcc
     7021 aaggtagcat caaccacgtc ctccatgatc tcctcgattt tttcaagctt ttcatgggca
     7081 ttgacatcac ccttttcacg catagactgc tccaagcttc tgaaaaaatc ctctggagtc
     7141 atttgagaaa tatcacctag gtctgccaaa tcctcaaaat taaggtcctt attgaggtct
     7201 gatttggtca caaaaacatc taagcgatcc tttcttggag tcactcgaaa gctaagcata
     7261 ccactgtcct taaaattgtc cggaaggccc aactcgtcca tgacagcata aaagaactcc
     7321 tctgtctttt cttgagggat caagaagtcc ttgagctcca tccccctttc ttctaaatcg
     7381 tccatactaa ttgttatttt tagcgttgtc tcgctaattt gtttcatttc cattgtaaaa
     7441 tacctcgcag gcgtagtcat tttattatac tagaaatact atgatttcgc aatttatgac
     7501 tagccttaca gcaagtaaaa gcagccttcc taggaaaact gcctgacgat ttctaaaaaa
     7561 gtgacttaaa tacactgtag acaatcaata agcttcccaa cacaatccgg taccgcccaa
     7621 agactgtaaa atcatgcttt ttaacataat ctgttaacaa tttgatcaca tacaaactga
     7681 ctgcaaaggc tgttaggctg gcaactaaaa gcactaatag ctgcgagagg gtcaaatggt
     7741 tgccatcaat aaaaaacttc aaagctttta ggccactata gccaaacatc gtcggaatgg
     7801 ccaaaaagaa ggtaaagtcc gcagcaactg tcctgcttgc tccaagaata atcgccccta
     7861 aaatcgttgc tcccgaacga ctggtcccag gaataatgct aagcacctga aagcagccaa
     7921 taaagaaggc tgttttatag gacatacgag atagcttgac gactcgcggc tcaagtgtct
     7981 gatttctctt ttcaatccat aaaaaggcta tcccataaac aatcaatgca atagcaatag
     8041 gaagcatatg attaaaatga gcgtcaaacc aatcatcaag tggtactgca atgataatag
     8101 acggaataca agcaatagca accttaagcc acagctgcca ggttagcctg atttgctgtg
     8161 ggctcttgcc aggctgaaaa gggttcaagc gttcaaagta aataacaata accgcaataa
     8221 tcgctcccag ctgaataaca atattaaaca tctccataaa ggccttatcc tgatgaagtc
     8281 tgataaattc ctgaaccaaa atcagatgtc cagtactgga aataggcagc cactcagtaa
     8341 ctccctcaat aacaccaaag aagatggcct tcagcaattc aataaataac atgttccctc
     8401 cttctaacaa agactctcat atctagcccg tcctaaaaga acaccacttc ctcctccatt
     8461 gccagcggag aagccgcaac cacagtcacc aagcaacagc aatggggtat tgcttttttt
     8521 gcttgttcat attgtaccat aaatgacacc gttaataaat cagtgacttc ataagaaaaa
     8581 gcttattttt aatcatttct tcacttgttt tatgaataaa taatcacctc ttttaaccaa
     8641 tgtattgaaa tagcttgtaa attactatag aatagtatta aacacgtttt taaaaaagga
     8701 gacctatatg aaaaagctag tccttagctg cttggccacc ttacttattt ttcttggagg
     8761 aataggtact gtgcaagcag atcactattt acgagttggt atggaggcgg cttactctcc
     8821 atttaactgg actcaagatg attcgtcaaa tggcgctgtt cctatcgaag gaaccagcca
     8881 atacgccaat ggctatgatg tgcaaatcgc taaaaaaatt gcaaaagcat taaacaaaga
     8941 cttattggtt gtgaaaacct cgtggacagg tcttattccg gctctgacct caggtaagat
     9001 tgatttaatt gcagctggta tgagcccaac agcagagcgc aaaaaagaaa ttgccttttc
     9061 taacagctac tacaccagcg agccagtcat tgttgtcgcc tcaaatggta agtatgccaa
     9121 ggctcgttct atcaaagatt tttcaggtgc taaggtaact gctcaacagg gcgtgtggca
     9181 tgtcaacctg ctaccacagc tagagggggc aaagcttcaa acaccaatgg gagatttttc
     9241 tcaaatgcgc caggctctaa cctctggagt gattgatggc tatatctccg agcgccctga
     9301 ggcaatgaca gccgagactg ccaacaaagc ctttaaaatg atcactctaa caaaaggatt
     9361 taccgtttca gagtcagacg ctgccattgc cattggcatg aaaaaaggag acgaccgcct
     9421 tacagcagtc aatcaagtgc ttgatgccat ttctcaaaag gaacgccttg ccttgatgga
     9481 caagatgatc caacagcagc caagcgagcc caaagctgat gaagcaaagc cctcctttat
     9541 caagcaaacc tggtcaatct ttcaaagcaa ctggaagcag ttccttcgcg ggacaggcat
     9601 gaccctcctg atttcgatga ttggtactat cacaggactt ttcatcggtc tcttgattgg
     9661 tatttaccgt acagcaccaa aggctaaagg caaattggca gcgctagctc aaaggctctt
     9721 tggtggacta ctcaacgtct atatcgaagt ctttcgtggg acgccaatga ttgttcaatc
     9781 aatggtgatc tactacggca ctgcacaggc ctttggcatt tccattgacc gcacactagc
     9841 agctatcgtt attgtctcaa tcaacacagg tgcttacatg agtgaaattg tccgaggcgg
     9901 tatctttgca gttgacaaag ggcagtttga agcagcaaca gcccttggct ttactcatgg
     9961 gcaaaccatg cgtcagattg tccttcctca ggtggttcgt aatatcctac ctgctactgg
    10021 taatgagttt gtcatcaata tcaaggatac ctctgtcttg aatgtcattt cagtggttga
    10081 gctatatttc tcaggaaata cagtggctac tcagacttat caatacttcc aaacctttac
    10141 cattatcgct attatttact tcgtcctaac ctttacggta acgcgtatcc ttcgctatat
    10201 cgaacgtcgc ttcgatgctg atacttacac taccggagca aaccaaatgc aagtttcgga
    10261 ggtcccaaat gtctaatccc attattgaaa ttaaaaacct aaaaaaatct tacggcaaca
    10321 atgaggtcct aaaggacatc tcgctaaccg tcaataaagg agaggtgatt tcaatcatcg
    10381 gttcatctgg atcaggcaaa tcaaccctcc tacgctcaat caacctatta gaagagccta
    10441 gcgccggaga aattctcttt catggtgaca atgtgcttgc agaaggctac aacctgaccc
    10501 attaccgtga aaaattgggc atggttttcc agtccttcaa tctctttgaa aatcttaacg
    10561 ttttagaaaa tgcaatcgta gctcaaacaa ctgtcctcaa gagagaacga tcagaggctg
    10621 aaaaaatcgc caaggaaaat ctcaaggcag ttggcatgac cgagcaatac tggcaagcca
    10681 agcctaagca gctatcaggc ggacaaaagc aacgtgttgc tatcgcccgc gccctatctg
    10741 ttaaccctga agccatgctg tttgatgagc caacatcagc tcttgaccca gaaatggtcg
    10801 cagaggtctt aaaaaccatg caagatctgg ctaaatcagg cttgaccatg attattgtca
    10861 ctcacgaaat ggagtttgca agagatgttt ctgaccgtgt cattttcatg gataaggggc
    10921 tcattgcaga agaaggcacg ccaaagcagc tctttgagca gccaaagcag gaccgaacca
    10981 aagcattttt acagcgcttt ttgtcataag cctaaaagcc agtctaacca taggtgttag
    11041 attggctttt tttgataagt cacatctgct aagcagcata atgatcatat agactacttt
    11101 agatcaaaga aaagacctat tataggacaa tttccctcaa caggcacaga taataaacct
    11161 ccttttgaag gttgtgctgc tactttttca aagctgctaa ggcaactggt ctacaaaaat
    11221 catttctcaa atgagacggt aactgttaag cttgatctct attctaaaat ttcaacacaa
    11281 aatactttac tggttaataa ctttgtgcta tactgtcttt attaacgtta ataatatatt
    11341 ttagtaggag gatagcatgg ccgaaaaaac tgacctcgcg tcagcttaca gaagactaaa
    11401 aagcccaaat attaaaacta aaaaacgtgc tctgaagatt attcacgagc acaaacgtta
    11461 cggtaaaaaa tagtattcta tttttatctc tccaaattta agtcagataa aaaatgatta
    11521 ggacaccatc cctccgtctt aatcattttt tgatggccaa gaaaagaaag ctttaagcat
    11581 tgttaaccat caacaagctg aggacacaca catctgatag agctgccaat agtagcagtt
    11641 aggaaatgct acactcagct tttaggtcca tgcttcagca ttttcaagca accggatacc
    11701 aagaaaacta accttttagc acagcacaaa gcggcacttg aactcacttt gttccctcat
    11761 ttgctctctt agcggctaag cttcaaaggt gattgaaaca acccattgca attggtctag
    11821 cttccaagct gtttgagcct gtgattcttg ctagcatttc agacatagca acatttttca
    11881 atagccatta tgcttaagac aatagtgaaa taaagacgac tgccttactt ttcaagaaca
    11941 ttgacgagcc atcatacaaa aagcaagctg atgctgacca gcttgcttaa tatatattat
    12001 cttgttttta aggctgatag cacctgagtg cgaatatcat caacaccatt tagagtattt
    12061 ggtaggaaaa gggtctgatt accctttgca gcaaaggtat tgagggtatc taagtactgg
    12121 ttggtcagaa gaattgacat gatctgctct tcattcagtg aaatattagc ctccttcaat
    12181 tcctgaatag aatcagccaa gccatcaaca atagccttac gctgctgtgc aataccaaca
    12241 ccatgcaggc gatccttttc ggcttccgct tctgctgcag ttacaatttt aatcttatca
    12301 gcattagcca attcctgtgc tgccacacgc ttacgctgag cagcattaat ttcattcata
    12361 gactgcttga cttcagcgtc tggctcaacc tttgtaatca aggtctttac aataatatag
    12421 ccataggttg acatttcttc tgctacctga tgctgcacct ccaaggcaat ttcatctttt
    12481 ttctcaaaca attcatctaa ggttagcttt ggaacagaag agcgcaaggc atcttcaata
    12541 taagacctaa tttgagcctc tggcttgatc aatttgtaat aagcatctat cacattttgc
    12601 tcattcacac gatattgagt cgcaacattt agcgtcacaa aaacattgtc cttggtcttt
    12661 gtttcaacaa taatctctga ctgcagcaaa cgcaattgca cacgcgcagc aatgcggtca
    12721 atcccaaagg gcaatcgaat atgaatacca ctagtagctg taccttgata tttaccaaag
    12781 cgctctataa tagcaacaga ttgctggcgc accacataca gcgtgcttgc cataatggat
    12841 aatatcacaa tcaccagaaa tccaataatc aaaatagctt ctaacatgtt aatctcctcc
    12901 ttataaagcc ctagctggat agctatacgg ctttttatga ttgcctcatt gttataagac
    12961 aattataaaa catttttgtc ttttgtcaat aaaaatctca acgtctatca gccggcttta
    13021 cagctgctag agaccactaa aagtctacac ctgacgacag gctgcaatca ttgcttctta
    13081 atagtcaagt cttccttcca aagacaaaag gagctaagcc ttgcctaact cctctctttg
    13141 ttctattcat tattcaacac tcataaggta tggatacaca ggctgatctc cctgatgcaa
    13201 ctcaacctct atatcctcat atgtttcctc gaggtaatca gcaagacctt gagccacttc
    13261 actgctgcca tcctcaccaa tgaagatcgt aacgatttcg ctgtcctcat caatcatgtg
    13321 atcaaaggta gtctttaggg tagcttccat gtctggattt gacactacaa tgctgccatc
    13381 gaccattcct aaaaagtcat tttcatgaat atcaaggcca tcaatcgttg tatcgcgcac
    13441 agccagagtc acacttccac taaccacatc agacaggctt gctgtcatat cagctacatt
    13501 atcctccaaa gtttttgaag gatcaaaggc cagcaggctc gtaaagcctt gtggaattgt
    13561 acgtgtctcc acaacagccg caggaatatc cacaacctcg gctgctgatt gggctgccat
    13621 gaagatgttt ttattgtttg gtaagataat cacctgctta gcattgacag cttcgatagc
    13681 cttaacaata tcctcagtag atggattcat ggtttgtcca cctgagataa cgtagtcaac
    13741 cccctgtgcc ttaaaaatct ctgccaggcc atcacctgca acaacagcaa tcaggccaaa
    13801 ctcttttgcc tctgccttag taggctcatt gtctattttt tgtacctgtg cctcatgctg
    13861 attgcgcatg ttatctactt taattttgat cagtgagccg tacttcagac cctcttgcat
    13921 cactagccct ggatcctctg tatggacgtg aaccttaacg atctcatcat catttactac
    13981 taaaagcgaa tcaccaagcc cactcaaata gccctgaaat tcatcataat taaattcttt
    14041 aacataggta ggaccctgct ttagagcaac cataatctca gtacaatagc cataggtaat
    14101 atcctcggta gcaacatgac ctgcaactga tttgtggtgc tcagccttaa tcatctcaga
    14161 catattggca ggagtggcct taaagtcctc agaagctaca taatcaccat ttaaggcaga
    14221 caagaagccc tcgtaaataa agacaagacc ttgacctcct gagtcaacaa caccaacctc
    14281 ttttaaaact ggcagcaggt ctggtgtttt tgcaagggct ccttttgcac catctagcgc
    14341 tgcttgcatc acctcaatgg cattatcagt aaggtctgcc tttttcaagg ctgctgttgc
    14401 tgcaccacga gaaacggtca aaatagtccc ctcaacaggc ttcatcaccg ccttgtaggc
    14461 aacctcaact cccatctgaa aggcctgagc taaatcctta cctgtcagct cctcttttga
    14521 cttgatactt tggccaaagc cacgaaaaag ctgcgaggta ataacaccag aattgccacg
    14581 cgcccccatc aagagaccct tggataggat ctgcccaacc tcaccaaccg ttgaagccgg
    14641 cttatcagca acctctttag caccattatc cattgtcatg ctcatattag tccctgtatc
    14701 accatctggt acaggaaaaa cgtttaagga attgacatat tctgcttgtt taccaagacg
    14761 agttgctgcc gcttggacca tttcttggaa taagcttgtt gtaatatttg acactaattt
    14821 tctcctacaa ctttaatatt ttgcacgtaa acattcacca tatccgcaga aagcccaagc
    14881 tgactctcaa ggttaaattt cacacgctcc tgaatatttt tggatacctc actaatttta
    14941 acaccgtagc tcataacagt atagacatca actgaaatac ccatgtccgt tgacttaaca
    15001 actacaccct tagcataatt ttctttgcga agtagcgatt gaaagttatc ttttagagca
    15061 cttttactag ccataccaac aacgccaaaa atttccgttg ctgaacctcc aacgacagtt
    15121 gcaataacgt catcagatag ctcaattaga ccatcttttg tattaatttt tacagtcata
    15181 gttactacct caaaaagttt ttatcagctt attttatcat aattcaaggt caatgtaaaa
    15241 agatataagc gaagaaaggt cacctctatc atgcttttct aagctttttc tgaaaacgac
    15301 taagaaaaaa agccctaagg cttatttcga ttagatgcgt tctactttac cagatttaag
    15361 cgcacgagct gaagcccaaa ctttttttgg tttaccatca acaaggatag taactttttg
    15421 aagatttggt ttaacagtac gttttgtttg gttcatagcg tgtgaacggt tgttaccaga
    15481 tacagtctta cgacctgtga aataacatac tttagccatt gtaatctatt tcctcctagg
    15541 tagaatatgt ttacggatgt gctagcacca catacttacc tagtctatca caactcttac
    15601 cttttggcaa gctatttttt acatctgcag gccttagcca ctaagcagca aaatgtccct
    15661 cttaatagct aagcactcac ttgctcctct cctataaata ggtctataag aatcaataat
    15721 accctatcta tcacaaatgt ctaagggctg ctgtcagctc gaaagccttc tcttagaacg
    15781 ctaaaactac tctaagaaat agaggttatt taacaggctt tgctgtagtt gcctagctga
    15841 aatcctataa gcatgcacta aaaaagacta aacaagacat cacacaacca cattagtagg
    15901 gagattagcc tgaggagtgc ttcttgttta gtcttttatc ctcttgaaag ccttgatcag
    15961 tatcgtgatt gctgatttct aatcacgctt ctctaactgc tcaggtgtga agtggtcaaa
    16021 ctgggcaatt aaaaaatcaa tatactcttc aaggtgtaaa agcttataga gaaaaacgtg
    16081 gctattaatg gtatcaatat aattacccat aataaagcca tctaaatcag aatctttaat
    16141 cttcttgatt aattccttct ttttttgttc aacctcttca tcagtgcctt tattttgctg
    16201 agacaggtac caggacctat tccaataaaa ggttgataca tgcgcaaaag ctgtccggct
    16261 agtaccgact gctaaaccaa gacaaacaga tagtagtcca aggcccttta aaagagactt
    16321 ttttgaaata cttagatctg ccatagcgag tcctcctttt tatttttcta accaaaccat
    16381 actaaaatat aactatattg taaaataaaa agtattgtat tagaaataag taaaaataaa
    16441 gctatgaata gttgacctaa ctaaacccaa caaataagat gctacatgac aaaattcctt
    16501 ttattctcac cacctgtgat ctcatcaaaa gctctctaaa ccagagaggc atagacagct
    16561 accgaatgaa gccttagtaa tagctgtctc agctcacctt aaactaatag ggtcgataaa
    16621 taaggagaca tttgcgcagc agaagctgat agtgtcaaag gttctacttc agcaagcata
    16681 tcatgagtca cctatttcag cacaggcttg gtaatgtttg gatagtacaa agcgtttttc
    16741 tcaagaacgt tcaagatcct tccagtcata gcagagcagc ccttaccaca gacatctgct
    16801 agcacacacc tcaaaaacaa agacataatc gctcaagtag ggctattctt tatcggcaag
    16861 gggattaggc gaaggaacta taaaaaggcc tatccttgcg gataaaccct gatttaatca
    16921 cgtttagcag tcattaagcc ttgtttgctg agccaaagac atcaatacgt tcttcaacag
    16981 aagcctggat cgccttaaca ccatctgcca agaatttacg tgggtcaaag agttttttct
    17041 tatcgtattc tgcaacgttt gcttcgtaat cacgcgcaaa ggcacgagta gcgttagcaa
    17101 atgcaatttg acactctgta ttaacattaa cctttgcaac accaagcttg atagctgctt
    17161 gaatttggtc atcaggaata cctgaaccac catgaagcac gattgggaag cctggtacag
    17221 catcagtcaa tttcttcaag tgatctagat caagaccagt ccagttttct gggtatgggc
    17281 catggatatt accaatacct gcagccaaga agtcaattcc tgtagcaacc attgccttag
    17341 cgtcttcaat cggagcaagc tcaccactac cgatgatacc gtcttcttca ccaccaattg
    17401 tacctacctc agcttcaact gaaacaccct tagcatgtgc tagcttaaca atttcacgtg
    17461 ctttctcaag gttttcttca actggaaggt gtgaaccgtc aaacatgatt gaagtgtaac
    17521 caacctcgat acattcaaga gcatcttcat agtgaccatg atcaagatgg atcgcaaccg
    17581 gtacagtgat gttcattgat tctacaagag tttcgataag aaccttagct agcttgtagc
    17641 cacccatgta tttagctgca cccattgagg tttggataag aacaggagct tgtttagctt
    17701 ctgctgcacg caggatcgct tgagtccatt caaggttgtt tgtgttaaat ccaccaacag
    17761 catagccgtt atcacgtgct gcttggacaa atttttctgc tgaaacgatt ggcattttaa
    17821 taagcctcct cttatatttt gggttaaccc catttacatt gttcatttta gcacaatttt
    17881 caagaaattt ccagcccctc atcagcttaa agcgttttct cgattcatct tatcacaggc
    17941 tcacaattga gcatttggct agcagcagtc ttttcaggaa ataaaaaaaa agatgaatcc
    18001 aagattcacc tctgcgatgc ggagagtggg acttgaaccc acacgaccta aagcggtcac
    18061 aggatcctta gtcctgcgcg tctgccaatt ccgccatccc cgcttgctct ttagcaacat
    18121 ataaaattat atcagctggg agctttactg tcaatactta tttctcatat ttttgcaaaa
    18181 aggccgcaat cttttccttg tactggtcgg gattggtctc aaaggacttg gcatgcttag
    18241 cccccttaac aaccattagc tctttaggac cttttgttgc ctgatagttt tgatagacca
    18301 tctctgtcgg gacaaaggta tccttgtcgc catgaataaa gaggactggc agcttatttt
    18361 tggccaattg cttcaccgag ctagcctcac catagctaaa gccggcacga attttagaga
    18421 gggctgaaac ctcatacagc aagggaaagg ctggtagatt gtacatggcc ttagcttgga
    18481 atttcaattc gtcccaaaca ctagtatagc cacaatcctc aacaatattg acaacctgac
    18541 taggtagctg ctcaccgctt gccatcataa cggttgcggc acccatggat aagccaaata
    18601 agctaatgcg actgccttta tcctcgctaa cgagcaaatc aatccaggca agtaggttca
    18661 agcgatcatt ccagccatag ccaatcaagt caccctcact ctcaccatga gcctcattat
    18721 ctggtatcag cacattgtag cctaggctgt gaaaaagcat ggcatagggc ttcatgtcct
    18781 ctttatcatt tgtaaagcca tgaacgacaa tagctgtctt atgagtatcc tgcgaggcag
    18841 gcaaatacca tgcaacctgt tgacgtcctc tgttagtgat gctgcgtttt tcacgcgtca
    18901 agctgtcaaa agctagctct gctgggtaca aaggattgtc tggggttcgt tttttattgt
    18961 tgataaatga cttttcctca cgcacctgag caacatggaa gaaataaaag ctagctccca
    19021 cactagccag ggtcaacaag agcagtaaaa tgccaaaata ctttgataat cgaatggttt
    19081 tcataccgac tattctacaa gaaaatatgg aaaaaagaaa gctttatgct aaaaataacc
    19141 gatacctttt tactgccttc ttaaggccaa atctcaagcc agccagtagc taaagcgttt
    19201 tcgcaggaat tgaagctcaa tagtttaaag aatatacaag ctaccttcaa aatagctttg
    19261 accagatcaa gaggaagtcc gctgacagca tttgataaga ggtaaaatgg tgctttttgc
    19321 tatattaaaa gtggctgatg tcatcatctc atcagccact caaagactta ataagcctat
    19381 caaagctgct aactctcagc acctaaataa ggctcaagga tagcctctta cgtcatacta
    19441 gacttaaagg ctttggtttt tatttttcac tgctgctgta acaaaggcag tgtatagctc
    19501 ttcaggacga ttaggacggc tttgcagctc tggatggtat tgggctgcca caaagaattt
    19561 cttctctggt aattctacaa tctctaccaa acgattgtcc ggcgaaacac ctgagaaaac
    19621 aaagcctgct gcttcaaagt cctgacggaa tttattgtta aattcgtaac ggtggcggtg
    19681 acggcgctgc accacctctt ggttattgta ggctgctgca gctcttgagc cagcttttag
    19741 cttacatggg tatagcccca gacgtaatgt tcctcccatg tcctcaatat caatttgatc
    19801 acgcataata tcaatgattg gataggcagt atctggatcc agctcaaacg aattggcctt
    19861 ttccatgcct aggacatgac gagcaaactc aacacaggtt aattgcatgc ctaagcaaat
    19921 gcccagcatc ggcacatcat gctcacgcgc atagcgaatg gcttgaattt ttccttctgt
    19981 tccacgctga ccaaagccgc caggaacgat aatgccatca gcctgcccaa gcagcttctt
    20041 agcgttttca gctgtcaggt cattagcatt aatccaatca agctcaatag cagtgtcatt
    20101 agcatagcca gaatgcttta gggcttccac aacagacaaa tacgcatctg gaagctcaac
    20161 atatttccca accaaagcaa tccttgtcgt tttcttgagg ttcatcactc tatcaaccat
    20221 agctgaccat tctgtcatat ctgcctgagg cacgtctagc ttcaagtgat cacagacgat
    20281 ttgatccatt gattgagcct gcaaattcag tggaatttga tacaaatgct ccacgtcacg
    20341 agattcaata acggcttctg ggttaacatc acaaaattgc gccagcttat tttttatccc
    20401 ctgctcaaca ggctcctcag tacgaatgac aagcatattc ggctgaatgc ctaagccgcg
    20461 taattcctta acagagtgct gtgtcggctt tgttttcatc tcgcctgctg cttttaaata
    20521 aggcagtagg gttgtgtgaa tatacatcac attttcagag ccgacatctg ccttcatttg
    20581 acgaagcgct tctaagaatg gcagactctc aatgtctccc acagttccac caacctcggt
    20641 aataatcacg tcagaatctg tggtcgtagc tgcgcgcttg atcttctcct ttaaggcatc
    20701 tgtaatgtgt ggaataacct gaacagtcgc tccaaggtat tcacccttac gctccttacg
    20761 aagcacctca ctgtagattt taccagttgt cacatttgag tatttattaa gattaatgtc
    20821 aataaaccgt tcgtagtgac caagatccaa gtcagtctct gcaccatcat cagtgacata
    20881 gacctcccca tgctgataag ggctcattgt cccaggatcg atattaatat aagggtcgaa
    20941 tttttgaatc gttaccttta ggccacgatt tttcaataaa cgtccaaggc tagccgctac
    21001 aatacctttt ccgattgatg agaccactcc gccagttaca aaaatgtact ttgtcataac
    21061 actcctttat ccttttgagt taagcctgac taactcgttt ttatttttaa aagatcgtcc
    21121 tactttagct agtaacgatt gggggctaag cttcccataa ggctaagcca tgagaccagt
    21181 aaccaaggct aagttattaa aacaaaaata gccccctatt aactagggag cttacctgac
    21241 ctcttaaaga ggtgcccgat taataatata aactataaga ggacatttgt caaatattac
    21301 tgttgctttt agaggctagc gatactcctg ctattcctcc tcttcctcat cttcttcgtc
    21361 ctcttcattg aggtcaacct cttcaaaatc gtcctctgga atgatttcat tgagctctga
    21421 atcgtaggac tctacttcag atttttcatc gtctggatct tcctcgtcat attcaatatc
    21481 agatgattca cgaacaaaat cctcatcctc tggatcatca gcgctatagt caatagcgtc
    21541 ctcatcaccg tccatgaagg cattgacacg tttcttcttg cgttttggtg cgccgtcttc
    21601 ttcatcttct agggtgatga tttcctcatc aatctcatca atagcatacc atgaacgtag
    21661 accccattta ttttcaccaa gtggaataaa gctaccatct gtattgagat cagtgtaaaa
    21721 aaatggtaaa gcatatcgaa tatcagcgtc agacttgcct aggtaatttt gaatctcatt
    21781 aaccaaatcg ctaaaataca tgtcattatc gcgaccacgc tcttctaaaa tagcacgagc
    21841 aacttcaatc atagaaagtt cgcttatttc ttgtcctgca aatacatcta atttcaaggc
    21901 agttctcctt attttatcat tctcccctat tttacgctaa aaataccgat tcgtcaaagc
    21961 ttttatcagg gaagaacagt attcttttta cccacttctc agccagcaag aacaaagcct
    22021 agcagcaacc agcttgattg ctcctaaacg cgataacaga agcatttcaa agagaagtgt
    22081 taactgtttg cctttaaacc atgaagcaac agcaaaacaa gaccaagtgc ttgcttagtc
    22141 ttgcttgtct atatcataac agcttatttt gcttttgctg agcttgtaat cacttctaca
    22201 gcttttttca taacaatgtc atgctttaac atatcagctg aaagcaatga gcgaacctgc
    22261 tcaactggca tgctatactc agctgcaagg tcgttaattt ctttttcaat ctcatcgtct
    22321 gaagcttcaa agccctctgc ctttgcgata gcctcaataa cgagattagt tttgacacgc
    22381 ttgtctgcct ctgcttcatg ctgcttgtga agatcttctt gacttgtgcc agttagctgg
    22441 aagtacatat caggtgaaat gccctgacgc tgcatgctag ccataaattc attaacggaa
    22501 cggtgaacct cgtcatgaac catttcctct ggtaattcca caatttcagc attctcaaca
    22561 gctaactcaa tagcagcacc ctctagagcg tcatcataag ctgcttcctt tgaagcctca
    22621 agctctttac gatacttagc ctttagctca tcaagtgttt caacttcctc gtcaatatcc
    22681 tttgcaagct catcgtcaag ctcaggtact tcttttgcct ttacctcatg aacagttgcc
    22741 acaaacttag cagccttacc tgcaagatct tcagcttgat aattttctgg gaaggttaca
    22801 ttaacctcaa cagtgtcacc agccttagcg ccaactagct gttcctcaaa gcctggaata
    22861 aattgtcctg agccaagctc aagtgagaaa ttgtctcctt tgccgccatc aaattcaact
    22921 ccatcaacag agcctacaaa atcaataaca actgtgtcac cttctactgc tgcttcttct
    22981 ttgacaacca gctcagcaag attgttgcgc tcgcgctcaa cctttgcgtc aacctcctca
    23041 tcagtaacct cttttgaagc ctcaacctca acagtaaggt ctttgtaatc accaagctta
    23101 acctctggtt ttgtgacaac ctctgcagta agtgtccatt cttgacactt ttccatagaa
    23161 accacatcaa tttttggctg tgcaacaaca tcaagctcaa gctctgcaac agcaccttca
    23221 taggctgctg gcagcacaat attcaaggcc tcctcataaa gaacctcttc accaaatctt
    23281 tgatcaaaaa caggacgagg catgtgaccc ttacggaagc ctggtgcatt taaatccttt
    23341 ttaattttat taaaagcttg atcaagagcg ggcttgattt tatcttgact aatggtaaat
    23401 gtaatcacgc cacgatttgt agctttgttc tcaaatgatg tagacattaa gtcatttctc
    23461 cttaaaataa tttagataca cctcattcta tcatattacc aagtgttttt aaagtttttt
    23521 atgcgtgaaa gtagggacag ggtttccaaa tatcagactc ttaactgaac cattaccaaa
    23581 aacctcatca gcttcaaaga aaaagagact ggaacaaaag tctgcctcca aaataaaaca
    23641 aacgaacaag acttgttttc tgagatccca aaaactagtc ttgttcgctt tttaattatt
    23701 tagactgggt aataaaatac attagctaag actttttaac atgcaactct ttttgtccca
    23761 gagtccaaac agtccttaat ctgtaagcca gatagttacg ctggaagtag gacagctact
    23821 gatttcttag ctagatgacc ggtaatgttg tgattggaaa catgataaac tgtgccagtc
    23881 actgcgtctt tgtagtcacc gtcagctagg gttgttgtag aagaaaagtc tttatcaacg
    23941 atggttaggt tggtgataac agcacccttt tgaccgcgtt caatcatgac tagaccttgg
    24001 tccataccag gattgcgaat atattctgat tgaccattca tcctattgcg gaattgatta
    24061 atcgcaacaa tggttggatc cttaaacaag tcactgccgg catcaccaat ttggctttct
    24121 ccagggaagc gtccattttg gccgccaccg ccacgaggac gtgaaaagaa gagcggtgct
    24181 ccctcattac gagcagcaat aattccccag ccaagcttaa tgtcctcatc tgttagcttg
    24241 gtagactctt catcatcgtt agcataggta tcatgagatt ctacccaagt gactaacttg
    24301 tcctctgaaa cgccatgcac ttggaaattc accaaatccc aatctttcac atagccttga
    24361 cctagcactt tacggattag cttaccatag tttgacgctg tcactcccat gatattgcca
    24421 tagcctgctt cgttgcaagc atcaccctgt aaaatttctc catattggaa tttagcacca
    24481 ttgttaagaa taaccttcca gaaatcgctg ttatgctcac ctggtaattc gatatgcttt
    24541 gcagcatcat acctaaagcc atctgctcca tcagctactg ctcgttttag ataattcagc
    24601 atgtattctt ggacagctcg attttgcgtg ttgaaatcat aaagtcctag caaggatttt
    24661 tgggttattt gataacgatc gttgaagttg acgattttgt catttccatg tgtccagtta
    24721 tctatggctg tgatcttagg gctaactgcc ttaatctcag aggttgtatg attcaaaaca
    24781 gcatcaacaa taatattgat cccatattta tcagcctcct gagccattgc cttaaattcc
    24841 tcttctgttc ctaattggta gttcccgata gtatagtctg ttggctgata atggtaatac
    24901 cagtttttca agtccttact accgccagct ccttcaatga cagcattaat aggtgaggtt
    24961 tgaatactag tgtagccagc ttccttaatg gcactcatgt tttctttgat ggtgttaaag
    25021 gaccagcacc aagcatgtaa aatagctccg tccttcatgg ctaccggttg attatcggac
    25081 tgcacctcct gagcactagc aaggttagct ggggctagag gagccaagcc tgaaagtacc
    25141 aagccaaggg tcaagctggt cactgataga gctttgagaa atctttttgt cttatgtgtt
    25201 accatatgta aactccgttc tttctgcgaa atcgctttcg ttgatgctta aaaaaataag
    25261 atgattctct gtactgtttg caaacaaaaa taggacctat gagagaagta taacatataa
    25321 atttcggtat gcataccatt tttagcaaaa aattagtgat ttttttaatt tttatttcct
    25381 ttgctaaagc ctctaaaacc aatcaaaata atgttgcata agtatttgcc ttttatttat
    25441 ctcataatca gactcattcg ctctaatctt ttgcacatgt taatgtcatt tatttgcaga
    25501 cctacgcaac caattgcaca gagctttgtt tccttcgtca gaaaaacctc aataaaacat
    25561 aaacaagaag ccattactct tcttgataat gtttggtgat ctattttcaa ccaggacttt
    25621 ttttggtaaa ctagctacga tagaaaggag ttgccatgac gtttatatta acatacttta
    25681 atcagctaca cctagaaaat atcatggtgc ttgtgttttc taaattagtg tcaatcacct
    25741 tattattgat tttctttgtg atcttcaaaa aaatcacgac agctttattt gaaaaggcaa
    25801 tcgccaagtc attttcctat tcaagacaaa ctgaagcaag gaaaaaaacc ttatccaagc
    25861 tccttcacaa caccctaaat tatgttttct attttcttct catctattgg attttgagcc
    25921 tacttggtat tccagtatct agtcttttag caggagcagg aattgctggt gttgctattg
    25981 ggcttggggc tcaaggcttc ttgtctgatg tggtcaatgg cttttttatt ctgtttgaaa
    26041 atcaatttga agtaggagac accgtcacca ttgcaggcat tgaaggaacc atctccagcg
    26101 ttggtattcg aaccactcag gtgcgaggct ttgatggcac actacatttt attcccaacc
    26161 gcaatattac agttgttagc aacaaatcac gcggcaatat gagagctttg atcgatattc
    26221 cactttattc ctcaaccgat ctagagcatg tgacccaaat catcaaggct gtcaataagc
    26281 gagaggtgcc aaatttccca caaattgtcg gacagcccaa cattctagga ccacaaacca
    26341 atcccaacgg acaattcacc tttcgcgtta gcatttttac tgaaaatggg cagcaattta
    26401 cgatttacta tagcttttat aagctctatc aagaggcctt actaagggag ggtatcaagc
    26461 taccaactgc atctgccata tcacccttag cctagcagta aaaaccattg ctttcttagc
    26521 atacaaaagc cctatcccgc agccaggtca tcagacttag actgctagat agggctattt
    26581 cttttggctc ttatttccga ataggatcag gctgatacct ggctcttaca ccaccaatta
    26641 atttgggccg acttgctaag gcagtcacat gagcaccacc aagctctcgc tgaataggca
    26701 caagcggcac ctgtacacgc ttaacatgca taccaattga ggtatctcca atgtcaaggc
    26761 ctgcatgagc agcaatggct tcaacctcaa ctggctgctt catgtatttg aaggctgcta
    26821 attgaccact tcctccagca tgcaagctag gcagcacatt gactatttct agccgatatt
    26881 cttcagcaac actttcttct aataccaagg cacgattaat gtgctcacac ccctgaaccg
    26941 ctaaatgaat ccctctgaac gacaattcct ccaatataag cttcacaata acctcgccca
    27001 cctctaagct agaatgctgg ccaatacgac caccaagtac ctcgctagag gacagcccta
    27061 agacaaacag ttgccctttt ttgatagcac tacgctccac aatatcaagc aagatagagc
    27121 gtgcttcttc tctcaatact tttaaattca ttgaatcacc tgcttaatca tctgacactt
    27181 tgaccagctg ttttttgacc cctaaataca gcagatagcc tacacctatg ccaagggtat
    27241 tttgagcagc attccccgaa atttctgaaa tagcagcgcc cataccatac attggaatag
    27301 ctgcaagaaa atacagacca accattatca cagaagcaag gcccacgcca agaaagcgat
    27361 gcctgccagg caagcctgct aagtagccct gagccccatg agcaacaaga ctaatcagca
    27421 tccaattcgg gtaacctgag atcaaatcaa gcaaaaaagc tgataagccc ccaacaagca
    27481 taccctcctt tttcccaaga gaaaaggcag tcacatacac ccctgcatct aaaagactta
    27541 aaaaacctgt cggcgtggca atactcacaa acctgcccag gacaactgtc agggcagtca
    27601 agatagacac aagagctagc tctcttgtct gtttcatatt tatcataaga caactccata
    27661 atcatttgac tgttgaatgg cttcaaaaac aaggtcttta gcctgctcaa cagccctaag
    27721 cggtgaatat cccttagcta aataagcagc aattgcagct gcaaagctac agccagcccc
    27781 actgttttgt ttggccaaga ctggcttttc taaaaagcac agggtttttg cgtcataaaa
    27841 tagatctagg gcaactcgtt gatcaaaacg attcccaccc ttgatcacaa ccctcttagc
    27901 ccccatctca taaagctttt ttgccgcttc taccatttgc tccctgctat taatagcaag
    27961 ccctgccaag cgttctgctt ctcttaggtt gggagtaatc actgctgtta agggaaaaag
    28021 agagcgcaaa gcctgtgtca tttccacaac tgtctgatct tgattttcct taaatactaa
    28081 aacaggatct aaaacaacag ggatatcctt ttttagctct aaaaacaggg ccacctgctc
    28141 tgctatttca ggtcttggca aaagaccaac tttgattgcc tgaaaaggaa tagctgctaa
    28201 gctagacaac tgctttgcca gcaaatcagt cgcaacaggg tgaatgctga aacctttagc
    28261 atcacagctt gttaagcagg tgatagctaa aaatgcaaag ctatcgagct gatgaagcac
    28321 tgccaaatca gcctgcaaac caccaccgct gaatatatca ctcccagcaa tcgttaatac
    28381 cttattcttc ataaatgatt tccttcaaat aaagaccatt accagccgct gtcggtccag
    28441 ctagctgccg attcttactc tctaaaacga gcctgatttg ttcaatgggc aaccgaccat
    28501 tgccgatctt aagcaaggtc ccaaccatat ttctaacctg cttataaaga aagccattcc
    28561 ctgaaaacgt aaaaacaaga aaaccagttt tagggtcctg agtgagggta gctgctgtaa
    28621 tggtacgaac cttattttta acagaggttc ccgcagctgt aaagcctgta aaatcatgcg
    28681 tcccaaccaa atccttaatc gcagcctgca ttttcgcaat atctaaggga taagggtaat
    28741 gggtcgcata atggcgcatc ataggatttt taggacgacc aatatccact aagaattcat
    28801 aggttttgaa atgcttatgg tagcgagcgt gaaaatcatc tgctgcaatc tccagactga
    28861 tcacatcaat atcatctggt gtctgggtat caagtgcaaa gcgaagcttt tcagggtctc
    28921 ttttttgctc caaatcaaag tgaatcactt gaccataagc atgcacacct gcatctgttc
    28981 taccagctcc atgaatctgt atcccttgac cacctgtcaa tttttgcagg gtcttttcaa
    29041 tctcttcttg taccgtacgt gcctgacttt gtctctgaaa accagaaaat aaggtcccat
    29101 cgtaggaaat aattgcttta tatcttgtca tgctattatt ctaccatttc ttccagccat
    29161 cagaaaagag catttacggc ttttgtcccc atacagtttt cgattagctt tgataatcaa
    29221 gcttgatttg acgccaacag gcaaaaaaag gctactgaca aggactagct tttctgctat
    29281 aatttctcta atattcaata agtagactgg agagcaaatg aaggtaacaa aatttggcgg
    29341 cagctcctta gcatctgccc agcagttaga aaaggtcttg gctattatca aggacgatcc
    29401 tgagcgtaaa atcatcgttg tctccgcacc aggcaaacga tcccctacag acacaaaggt
    29461 gactgatgca ctcattgctt attacaaagc ctacgtctca gaccgtcatt atcacaagca
    29521 tttggaatgg attatcaatc gttaccaaca aatctgtaat gacctaactc tagatagcaa
    29581 aatcatcacc caaattaaag cttccttaga gcaattggca cggcttccaa aagaacataa
    29641 tccctattta tacgatacct ttcttgcggc cggtgaggac aataatgcta agctagtagc
    29701 tgcctacctc aaggcaaatg gcttaactgc aagctatctc caccccaaag atgcaggtct
    29761 aatcgtaagc agtgagccac agcatgcacg tcttcttcca atcagttacg ataagctaga
    29821 ggccttaaag gatcatgatg acattcttgt tattcctgga ttctttggtg tgacaaatga
    29881 aaaccagatt tgtaccttct cacgtggtgg ctctgatatt accggctcca ttattgcagc
    29941 aggagtcaca gctgacagct atgaaaattt tacagatgtc aatggcatct ttgctgccca
    30001 ccctggtgtt gttaagcagc cacagacgat cactgaatta acctacagag aaatgcgcga
    30061 gttagcctat gctggctttt ctgtcctcca tgatgaagca ttaatccctg cttaccgagg
    30121 gaaaatccca atcgtcatca aaaacactaa caatcccagc cacccaggta caacaattgt
    30181 tcttgagcac cagaggaaat ccaatcccgt tgtcggtata tcaggtgatg atcactttgt
    30241 cagcattaac ctatctaaat acctcatgaa cagagaaatt ggatttgggc gcaagctcct
    30301 tcagatatta gaggacctca atatcagatg ggagcacatg cctacaggta ttgatgacct
    30361 atcaattgta cttagagaaa gagaattgac ccccatcaaa gaagaagaaa tccttcgcag
    30421 acttgtccag caattagagg ttgatgaggt gtccatcacc aggaaccttt ctattatcat
    30481 gatagtcggt gaaaacatga aaagtcatat tggtgtcaca tctgccgcaa caaaggctct
    30541 atctgaacat catatcaata ttgctatgat ttcccaaggc tcaagtgagg tatctgtcat
    30601 gtttgtcatc aatagcaccg atgaaaaaaa ggccattaga gccttatatc aaaccttttt
    30661 tagccctgat cgacccctgt aaagctccat ataacatctc ttgttaacac caagcttcaa
    30721 aaacagctca caagctagac agtactccta gcctatgagc tgttttgatg atctaaaact
    30781 atcaagatta agcatcggta gtaacgactt aatatgctca cagctatcat aaactctagc
    30841 tttaccttat tgaggaaaag aaaaccagtt ttcacctcag ctaagattaa caacaagcga
    30901 ttaagcactt gctaaaaaca gatagacttc aaaagtgaga catatgtata atttctacca
    30961 gatctaaata aatatagcag cagagcaccg agtttaataa gccatttctg acatgataaa
    31021 ctcgccaagc tctccacaga tcaagatttg ccttatcaat tgatacaaca gccagcattc
    31081 tcaaagatgc acaagatcca tcacagtcta gccatctccc tgcacagtaa g
//
LOCUS       DARYMD010000026        30257 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.026, whole genome shotgun sequence.
ACCESSION   DARYMD010000026 DARYMD010000000
VERSION     DARYMD010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30257
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            116..328
                     /locus_tag="TU818_001082"
     CDS             116..328
                     /locus_tag="TU818_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL0923904.1"
                     /translation="MSQQHRKWSALVEQRLKEKDWTKGDLALAVGLRSSGTITDLLAK
                     GKGSVDLKVRVSKILGIREPWELFER"
     gene            401..652
                     /locus_tag="TU818_001083"
     CDS             401..652
                     /locus_tag="TU818_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923905.1"
                     /translation="MDNILMSLSDWIKEIIEKTVNRLVQIKLDEANAELLTREKVADR
                     LNMSPATFDKYYRYDKNFPSELPGVRWKKAEIIAWLNNK"
     gene            928..1269
                     /locus_tag="TU818_001084"
     CDS             928..1269
                     /locus_tag="TU818_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923906.1"
                     /translation="MTQAERIREFYKENPTASYDEVAEAIGTTNSNVRANIAKDIKAG
                     RCVRLEDKSLDYSAHFGATEALADLVDWKNDTRREWVEMLTRAAEKETDSNTMRLLIK
                     EANKLMKEVTK"
     gene            1269..1751
                     /locus_tag="TU818_001085"
     CDS             1269..1751
                     /locus_tag="TU818_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEL0923907.1"
                     /translation="MAKLYELVGEYRDLYELNLDDETLKDTLDSIDWADRLSEKVEGY
                     AQVIETALAEAKMFEEAEKKFKAKKEAAKKKAAWLQGNVFDAMKLTNQTEIKSGIFTV
                     RIKQNPESVKVDEELLPKKYFNKKITVAPDKTTLKELLKSGKKIKGAELIRTEKLVIK
                     "
     gene            1748..2221
                     /locus_tag="TU818_001086"
     CDS             1748..2221
                     /locus_tag="TU818_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923908.1"
                     /translation="MMILAIDPSSNRIETSTTGIVLLDNARLVDYWVVPFGAENFKKW
                     FKDIGRTLEFDTVVVEKFEVRDNDYSRDNSVVETISAIELCYPDLVLQRNAGYQTDIP
                     NGLLKALGLWSFDKSHHNDVRAAARLGLFWAQRNDIEEVIVDIGNRITQMASGSS"
     gene            2181..3356
                     /locus_tag="TU818_001087"
     CDS             2181..3356
                     /locus_tag="TU818_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923909.1"
                     /translation="MAIELRKWQAEAVKRSDRDCPGIFLEAYGGRGKTICAFEIAKHK
                     EAKKVLVINNRLAILNGWNNTHQDLGYVNDFELEIMTDRRLQNRLASGESIECDVFVI
                     DEWQNMSSDANVKAYKKVKRGYTVGLSATPIRKKGQNFYPLEKTIFGMAEPNQRENWQ
                     LAHGKMKYSKFSYSKQEWDDFRNYESYVANLPNFFRWEDVEAIEEAEENNGFEVIFEP
                     VWCPPANPKELEQFRSLNIVGKDGKFAMAKQTFGRKIFERYLIQTGFEIDFPKLKAIN
                     ADTPMLIQLDLLLASHTEMLIVSKSKQIVEVIRERHPEIGIWTGDKKDALEQTNVVAT
                     TQVLGVGVDGLQYKFKTIVVLDPVNPSDGDYDDYRQLLWRVTGSRQQHDVRVIEFYF"
     gene            3366..4076
                     /locus_tag="TU818_001088"
     CDS             3366..4076
                     /locus_tag="TU818_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEL0923910.1"
                     /translation="MAEHKESGIFIVLRCIQADLIAPKGQYNSFGKYAYRSAEDILEA
                     LKPLLKKYDASIVLSDEIVQVGERYYVEATATLYAMGECVGNKAYAREDETKKGMDGA
                     QITGAASSYARKYALNGLLAIDDNNDADTDAYHNQNNQSAGKTQKTNQKQASQQESTA
                     KAPAKNNGSKTITGAQAKAIRTELKNMAEATGSPAAAIGNWFIGKMGVDKPENIPAER
                     LKEAQQIIADAKKVKGIE"
     gene            4077..4469
                     /gene="ssb"
                     /locus_tag="TU818_001089"
     CDS             4077..4469
                     /gene="ssb"
                     /locus_tag="TU818_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0923911.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGVLIGITGRIQTRNYENQQGQRVYVTEVVADNFKM
                     LEYRQQQQQEDSFDNNNPMDIQADDLPF"
     gene            4483..5310
                     /locus_tag="TU818_001090"
     CDS             4483..5310
                     /locus_tag="TU818_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEL0923912.1"
                     /translation="MGMKEYALAYQKKGFSVLPISPTGKKPMIAFADKPPMTAQEIED
                     FWTQYPDSNIAVRTDKFFVIDIDLHGKANGFESLANWEHLDLITPTLQAKTASGGKHI
                     FYFKHPDVSMTQMIGFLPGVDVKAHLNNYVLVAPSKTPKGVYAWDKDKSKEDGTMVTA
                     SRKLVMAIKQEYNKKNPGSDLDNIYYQISKGAGKRNRTTELFEMIVLGFGDQGGRNDT
                     LARFVGGLLSRSVDPECILRLAETANNNSVEPLGKREMRRTIESMIKKHMRGGGHNR"
     gene            5294..6694
                     /locus_tag="TU818_001091"
     CDS             5294..6694
                     /locus_tag="TU818_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL0923913.1"
                     /translation="MATIGEIVNISIKQFSRRKKKILSEEGEQIEVESIVADSPRNVL
                     LAMKSDNKLNDFLRHNEFTGEHEIVEDVKLDAIQLRRGQLPSTFESYLSVYLENHFKT
                     VFKAGALRDGIEAFFAEKTYNPVQEYMEHAYESWDHRERLAQVFQTWLGAEDSIFVQR
                     IAVMFFVGAVSKVFNPWVKFDYTLDLVGGQGAGKTTFLQKVAVEWYTDSAKDFMDKDN
                     YEIMLKSLIVNDDEMVASRKTTFDELKAFVTKTELSFRRSYGRRAEKFPKNFVIARTS
                     NKVEYLGDKTGERRFLPVLVDADQQLVKPFDMTDRDVLQLWGEAVAIYKKGFTLTFDD
                     DFEDELAVYKERFTYKDEAESQIYDYLDMLVPDEWEEMSVVQQHQYTWAYFNNGSYRN
                     ESGFVYEGVKLQASVSAKQILKNVFDIDSARGERIARKIKLIMDNHQDWEYRIKKIKG
                     RTVRAYFKKNMQNEVM"
     gene            7050..7244
                     /locus_tag="TU818_001092"
     CDS             7050..7244
                     /locus_tag="TU818_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923914.1"
                     /translation="MSYKVLVYFDNMLDEEYKFKTEKDASKCHDQLRRKYQGQRLYKV
                     KMEEVEEEVIITNFREVDHD"
     gene            7237..7464
                     /locus_tag="TU818_001093"
     CDS             7237..7464
                     /locus_tag="TU818_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923915.1"
                     /translation="MTKDDFLTGFVLILLAACIFAVGFAIGHDYSSEHYEQKITDLQI
                     QLVSTQQQLKQSREQNQSQTKRIANLTGNGG"
     gene            7475..8164
                     /locus_tag="TU818_001094"
     CDS             7475..8164
                     /locus_tag="TU818_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL0923916.1"
                     /translation="MEIKCGNCLELLTELTDGSIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGADLLSWIDIASRKLTKNGGMVIFNDWKNLGDIARHCEKTGLAVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGIWVVRKNSKWVFNRKSEKYDRPEYRYPIVSGAEKTQH
                     PTQKPVALMRDIITRHTTKRAVVLDPFMGSGSTGVACLLTERDFIGYELNKDYFNIAN
                     KRIAELTGNGG"
     gene            8166..8957
                     /locus_tag="TU818_001095"
     CDS             8166..8957
                     /locus_tag="TU818_001095"
                     /inference="COORDINATES: protein motif:HMM:TIGR00675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL0923917.1"
                     /translation="MLRVFEAFAGIGTQRMALRNLGIPHEVVAIAEIDKFAIKSYEAI
                     HGPVNNLGDISKINPDTIPDHDLFTYSFPCQDISVAGKQAGLDIDSGTRSGLLWECQK
                     VIVAKKPKYLLMENVKNLVGKKHKPNFDKWLDWLESQGYTNDWQVLNAKDYGVPQNRE
                     RVFCVSILGEHKPYIFPEKQELTIRLKDILEDDVDEKYYLTTNKANELLATIVRENDV
                     SERVVVDSTIKKPKIKNVMNAVIGRYDAGIRNQQSVGGAVIELIE"
     gene            8899..9444
                     /locus_tag="TU818_001096"
     CDS             8899..9444
                     /locus_tag="TU818_001096"
                     /inference="COORDINATES: protein motif:HMM:NF012372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL0923918.1"
                     /translation="MQASEINNRLEVLSLSLLNKNATKKGYLVADDGDGIDTAYPDSK
                     TRKGRVQKNMSHTITTDDSKAFLIGASRGRDPENPNDRSAGNQNLQQRLEINKNGTSN
                     TITSVQKDNYAVEFPDYRIRKLTPLECWRLMGCSDEDFEKAQSVNSNSQLYKQAGNAI
                     VVDVLEAILKQLFLTEAQNEH"
     gene            9434..9952
                     /locus_tag="TU818_001097"
     CDS             9434..9952
                     /locus_tag="TU818_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL0923919.1"
                     /translation="MNIEEAKQKLHNMAYRDLQTKPYDLKLADVIQILNQIKLDKPQP
                     EIPQFVADYIDDMHKNARTLRYAFKYMESNIKMHKWCVFEKQETFVNAFLYGYTIEKE
                     KLYTVEIPNPKNGIAHRHIMLVKTTDGRVVLSEVVDSHIHLRDDLRLTESEIRKDFDW
                     AWREEFPKEVTE"
     gene            9979..10278
                     /locus_tag="TU818_001098"
     CDS             9979..10278
                     /locus_tag="TU818_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923920.1"
                     /translation="MNYDKKKSDLKKRLIIGFTLLPISIVLSGFVIKYGWNNILSTID
                     GVPPINLPQAIAIDVLVSFIIAKTNAEGDFATEVGRAFISPLMTLLLFWVVTLFM"
     gene            10295..10468
                     /locus_tag="TU818_001099"
     CDS             10295..10468
                     /locus_tag="TU818_001099"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923921.1"
                     /translation="MTEELGVLLDKEGVEYVKMVFDDGFVWTIRNPLNAALLKRQDAE
                     QFPQFTWVPLTDL"
     gene            10805..11245
                     /locus_tag="TU818_001100"
     CDS             10805..11245
                     /locus_tag="TU818_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL0923922.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVPSKPVERLALNRVSAEQELDAIERAVNGIFDPEYRLILIDKYLLTYPKTD
                     CDIYTKLGYEKSQYYNMLDNALMSFSELYKEGMLLVEKMEKSWN"
     gene            complement(11643..12020)
                     /locus_tag="TU818_001101"
     CDS             complement(11643..12020)
                     /locus_tag="TU818_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL0923923.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGKDFQEAYEMAVEVLG
                     FALEDYTDYPKASSVSDLKEQYRDSDIALIGIDMIAYMKKYHSKKVRKNVTIPEWLNK
                     AAEDENLNFSQVLTEALELKLQA"
     gene            complement(12072..12257)
                     /locus_tag="TU818_001102"
     CDS             complement(12072..12257)
                     /locus_tag="TU818_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL0923924.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPLHNK
                     DLGKGLEDTILKQAGLK"
     gene            12373..12708
                     /locus_tag="TU818_001103"
     CDS             12373..12708
                     /locus_tag="TU818_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL0923925.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDRKTKQFYN
                     SKIWRETSKQVLLQSDYICAMCGGEATMTDHIVSVKKDWNKRLDWNNLQASCKACNDC
                     KAIRERRKT"
     gene            12871..13338
                     /locus_tag="TU818_001104"
     CDS             12871..13338
                     /locus_tag="TU818_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL0923926.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            13353..15107
                     /locus_tag="TU818_001105"
     CDS             13353..15107
                     /locus_tag="TU818_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL0923927.1"
                     /translation="MTIEYDYSAIGDIYKDDAFYYAKKVVDEEIKASKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPKKAIDPIIFIELLPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDEEIV
                     DDGYFGYVAEQDNEGEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKQSWELARIDKPDTHKRRVWLGVDVGRVSDLFAITPVIM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEVNGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KNGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTSEKILGGETLF"
     gene            15104..15274
                     /locus_tag="TU818_001106"
     CDS             15104..15274
                     /locus_tag="TU818_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923928.1"
                     /translation="MIGFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIFL
                     AIYVDSVGGKHE"
     gene            15267..15533
                     /locus_tag="TU818_001107"
     CDS             15267..15533
                     /locus_tag="TU818_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923929.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEALRNQNRQIAELRSIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWRK"
     gene            15567..16787
                     /locus_tag="TU818_001108"
     CDS             15567..16787
                     /locus_tag="TU818_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0923930.1"
                     /translation="MSFFQPLGSSKVSYDDYVSSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDMLTAKQVKCFAHDVIHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILKMKGAHISGEARKR
                     ARVEFEKMREGAIGGSPLVFDDTQEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLSDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            16765..17430
                     /locus_tag="TU818_001109"
     CDS             16765..17430
                     /locus_tag="TU818_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL0923931.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEQFPEDNSDI
                     VLEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFKWVSGNSDDLDKASNALKSSDKAIVSAYVAKTGLSEDAIMDLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNSMLPQAVIDDYYRSRNKRKQEISNMLLEIEKEEIL
                     RGL"
     gene            17455..18642
                     /locus_tag="TU818_001110"
     CDS             17455..18642
                     /locus_tag="TU818_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL0923932.1"
                     /translation="MFEEKIKEIKANIANLNQAIATKTTEVKNALESDDLETARSIKA
                     EIEEAKANLAEAENDLKLYEASIEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEALRFEGKDEVLIPLNQTTPVAPDTDGIKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKASGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEVKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEAKAGVKTLDDIKKILNVDL
                     DPAYNVSFIVSQSFYQSMDTLKDENGRYLLQDSITSASGKVFLGKPVFVLSDDVIGKD
                     SAFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVAKVDDKAGYYVTFKPEQ
                     LPS"
     gene            18787..19089
                     /locus_tag="TU818_001111"
     CDS             18787..19089
                     /locus_tag="TU818_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL0923933.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFDDDIIKEMIESAQEQICFAIEDG
                     STPEKFKGHAKFNLAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            19086..19433
                     /locus_tag="TU818_001112"
     CDS             19086..19433
                     /locus_tag="TU818_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEL0923934.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAVRKDLYTCWAEVLKTQ
                     LRDFNYQSKYQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFGKRIYKIDKIESDES
                     GKDIIMISGVSMS"
     gene            19430..19807
                     /locus_tag="TU818_001113"
     CDS             19430..19807
                     /locus_tag="TU818_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL0923935.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAKEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAAKVKEGLGL"
     gene            19804..20229
                     /locus_tag="TU818_001114"
     CDS             19804..20229
                     /locus_tag="TU818_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923936.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGPFKNGFKQGIFTYDIPD
                     NPVDLRKVDLAPFMRINTTLDGPADYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLINVRKYRYFDFY"
     gene            20245..20835
                     /locus_tag="TU818_001115"
     CDS             20245..20835
                     /locus_tag="TU818_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0923937.1"
                     /translation="MGKVKFGLRDFQYAVLGDDDQLKTKTGGIKSLPGMKSAKLDITN
                     ELVTVAADDGPYVVLSGGITETKLEIEVLDLTSDARKDFFGIKEEDGIEKYNKELTPN
                     DVACMFRTSDENGKAIWIGLLKGKFNIPGMEMQTKEGAPDPKSDTVTGNFVSRGKEGD
                     VIVIGRESASGFKLEKFKEFVFAGATDIKKGENFEM"
     gene            20887..21213
                     /locus_tag="TU818_001116"
     CDS             20887..21213
                     /locus_tag="TU818_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923938.1"
                     /translation="MYEITLKKGGVDKVFSKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMSVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            21261..21410
                     /locus_tag="TU818_001117"
     CDS             21261..21410
                     /locus_tag="TU818_001117"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923939.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            21423..25082
                     /locus_tag="TU818_001118"
     CDS             21423..25082
                     /locus_tag="TU818_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL0923940.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAKVTELQNRLRSLATETSVFTRFGKAAERIGGKMKSFGDSVAGVDAAFTR
                     GVTAPIVAGAGYAIKAAVDYETAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGVKTGDILSFSRTMIYLGESTNLSAEEAATSIAKIANITGLASSEY
                     SRFGSAVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQSLSAIERAVASGGDNLNKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDDLGLSGIRQSNMLKSLGLASETLGKALDTSNKAWQENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIVKWGLIAAAAGPALSIFGKGVGIIGGTIQAMGKMSRGLGTLSGWLRTFRTGA
                     VAASAGAEAATASMGGMAGAVALLSNPVTWGVLLGGAAIVGIGLIADSMYKAQKRTEE
                     WGIKVSQVQANELQRFKNKVDEANLAMTTFGVRSANNLDKIKTSFKALADEIEALQNK
                     KLKKDLKLAEKLGLSQETIEEIRRQADQTVATVRGMSDKVVDIYRRAKEERRSLTEEE
                     KTVVTKNLNDMIQTELSLMNYSKKEKIAILKAMNGEIETLNYEQLKKAQEVAQKMIES
                     ENKTYKKRRSNLKEMYDNIKGDSETAVRAREEIHRQLETLEDSHTAKMESLGERYLKI
                     RKKLLVDPALDPRVKQAMIDSLDKEFEKLGLSFEKLSKRSEEASSKTKISMQDMTSSF
                     RASIGEAISSLQGWDNLTPQEKQLLIDGNKAVSEILNSKTLLEQWQALTPQQKELLAK
                     NLTQDPTLSAQQAIDNVKQRVPADVKASDKTAPDVASADRAVNRPKQKGPAIIRAQDN
                     ASSVASGVIGWLNSIPRTVTSTITTIVRKITGHKTGTDYHPGGLAMVNDQKGPLYREL
                     ITLPTGESFIPEGRNVILPLPRGSKVLRASRTKQLFSHYANGIGFNDTKIASLTTRLK
                     SVQDKGQVIVNTDPQLAELIKLLKDRDNRNVTNNYTLNATNRSNSDDMFNQENMRRLL
                     RELAYYTNGEKGRLA"
     gene            25082..25789
                     /locus_tag="TU818_001119"
     CDS             25082..25789
                     /locus_tag="TU818_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0923941.1"
                     /translation="MRYIEFNGKKSDSFGLLLERERSIKSTSNDVDLIEVDGRDGVLL
                     KDNGRLKAIEQDFPFSLVGDVAVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVSLVNGGTLQNLGNVQSKPILKIKGTGN
                     GVLTINGFETGLENVQGELIIDMERHLVYKDILSAWDNIVRTERHRMPLFDIGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            25786..27927
                     /locus_tag="TU818_001120"
     CDS             25786..27927
                     /locus_tag="TU818_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0923942.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVRVTRERNGNYSLYIKYP
                     LDGVFASVFKEELKIKSDAGRRTKWQTFEINRVLRNSKDHIEIFARHISMRTQDIALK
                     PFVSGSSIDAESALEVWRDNLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKAPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEASGKPHIGEQEQPEEQLVTLPEFILDGQYLDLYAQRRIQMVDLSSHFN
                     DDKKEPTVEEIRKLAQKYLKDNNVGAPKISIEVDYIDLSQTLDYQDFRVMEEVELCDI
                     VPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVTQRIETLEN
                     NQKVITNNQQQFELNLPKYLNDLNGTKIWYEKPDDNVEHKIGDFWFEKNGKYQRTWVW
                     DGNQWVKIIDTEDLNPNQRAFDEAMAEIEKLKQHQRELDERNQKELEEFRETLKNLSL
                     PEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTDGKTRYNKNLL
                     VGDPNRVKKIDEDFIEVEANDGGFRRGETYTISFSQTCELLKKVAITLTQANNKGVKL
                     VLIPTKAKMEAQTFNLSKDKEVISVYPLSYRAVLTGDWYKSKQIELNAAEVQNLALEM
                     SYRDVVDSNNASLILDWSPNPDVIFDGNGGS"
     gene            27927..28688
                     /locus_tag="TU818_001121"
     CDS             27927..28688
                     /locus_tag="TU818_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0923943.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGPQGPQGLSGDRGPIGQTGPQGKQGVSVQSASVDSEGYLTVLL
                     DNGQSFKSDSSLKGSKGDTGPKGADGKMTFEQLTPEQKQQLKGDKGDPGPKGDIGPRG
                     ATGPQGPKGEPGINGMDGPRGATGPRGLQGPLGKDAVLPDDVVRRGELAAYLLRSEYK
                     AKGSGSGLSYKVVTQSEYDDLYDYNDNELILVTEG"
     gene            28690..29307
                     /locus_tag="TU818_001122"
     CDS             28690..29307
                     /locus_tag="TU818_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923944.1"
                     /translation="MAYKLYTKADVGDNMLLVAGRPLPDDTKRLKIQRETLDVLTITH
                     YGSYDMVHLKSTVKKAYSKNTVVTPVSAAASKPKAKPKHVLNFAKANKVYIGSTRVIA
                     VYLGDRLIWSDKHSSGTKTVSVVGSLDIRQSQKMLYLYLIAPDVADVKSKRIKSIAIN
                     GVKLSSTAQISFEGSSYYYLVTIKQVANIKEIKNIASKNKITLEF"
     gene            29318..>30257
                     /locus_tag="TU818_001123"
     CDS             29318..>30257
                     /locus_tag="TU818_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL0923945.1"
                     /translation="MSRDPTITLDESNLVIGQDGRMHYTFVAQDDNQKVRLASNCLGT
                     AHFNQLMIERGGQATDYVAPVVVEGSGKPTGLFKDLKELSLELTDTANSQLWSKIKLT
                     TNGMLREYHRDHIKTEIIESADGIAKRIADDTGQKLALINETINGIRREYQDADRQLS
                     ASYQAGIDGLKTQLANDKIGLQAEIKLSAQGLSQKYDDQIRQLYSKITTTSSGTTEAY
                     ENKLEGLRAEFTRSNQGLRTELESQISGLRSVQQSTASQISQEIKDRTGAVSRVQQDL
                     NSYQRRLASAEGNYSSLLQTVKGLQSTVSDPKGKIQS"
BASE COUNT        10163 a         5145 c         7010 g         7939 t
ORIGIN      
        1 agtaggaggt gagaatttgg ataatttaca aagacgttta gaacattttg taatcagagt
       61 atcgagacat tgcaacctca cgtttttatt ttaattatat cagaaaggag aataaatgag
      121 ccaacaacat cgaaaatggt cagctcttgt tgaacagcga ctaaaagaaa aagattggac
      181 caaaggcgac ttagcactag cggttggttt gcggagttcg ggaacaatca ctgacttact
      241 cgcgaagggt aaaggtagtg ttgatctaaa ggttagagtt tcaaaaatcc ttggaattcg
      301 tgaaccatgg gaattatttg aaaggtaaca aaaaagtccg acgggaatcg gactcaaaac
      361 aaaaatttac tacttagatt atatcacaaa ggagctaact atggacaata tcttaatgag
      421 tttgtccgac tggataaaag aaattattga aaaaacagtt aacagattag tccaaatcaa
      481 attagatgag gcaaatgccg aattattgac tagagaaaaa gtagcggaca ggcttaacat
      541 gagcccggct acttttgata agtactacag gtatgataaa aattttccaa gcgaattgcc
      601 aggcgttcgt tggaaaaaag ctgaaattat cgcctggcta aataacaaat aagacttttg
      661 gacgaggtct aatcacaagg gaagaaacac tggaaaacaa ttaggagtgt aattatgttt
      721 aataaaaaga aaaaattgca gaagtcattc aataatatta acaagcacat tgatagtctg
      781 acgctgtcag aacaagaaaa gcgtaatcta aaaggattgc tccgtaatgt caaaattaga
      841 acaagggtgg cgtgatgaat gcaattggta tgtatagcat tttagagcgg ctagaccggc
      901 ttgaaaaaat cgtatttgaa acagtagatg acacaggcgg aacgcattag ggaattttat
      961 aaggaaaatc ccactgccag ctatgatgag gtggcagaag ctatcggaac gactaatagc
     1021 aacgtcagag ctaatatagc caaggacatc aaggcaggca gatgtgtccg cctcgaagat
     1081 aaatcattgg actactcagc tcattttggg gcaacggaag ccctagctga tttagtagat
     1141 tggaaaaatg acactagacg ggaatgggtg gaaatgctga ctagagcagc agagaaagaa
     1201 acagatagca ataccatgcg attgcttatc aaggaagcta ataaactgat gaaagaggta
     1261 acgaaataat ggctaaatta tacgaactcg ttggggaata tcgggattta tacgagttaa
     1321 atcttgatga tgaaacctta aaagatacgc tagacagtat tgactgggca gacagattgt
     1381 cagaaaaagt tgaaggctat gcccaggtta tcgaaacagc acttgctgaa gcgaagatgt
     1441 ttgaagaggc tgaaaagaaa ttcaaagcca aaaaagaggc tgctaagaaa aaagccgcct
     1501 ggttgcaagg gaatgtcttc gatgccatga aattgaccaa ccaaacagaa attaagtcag
     1561 gaatttttac agtgcgaatt aagcagaatc ctgaatcggt aaaagttgat gaagagttac
     1621 tgccgaaaaa atacttcaac aaaaagatta cagtcgctcc ggacaagaca acgttaaaag
     1681 aactgctcaa atctggaaag aaaatcaagg gagcagaact aatacgtaca gaaaagttgg
     1741 tgattaaatg atgatactag caattgatcc aagtagtaat cgaattgaaa ctagtacaac
     1801 aggaatcgtc ttactagaca atgcaaggct agttgattat tgggtagttc catttggtgc
     1861 tgagaacttt aaaaagtggt tcaaagatat tggcagaact cttgagtttg ataccgtagt
     1921 ggttgaaaaa ttcgaagtta gagacaacga ttattccaga gataattcag tagtcgagac
     1981 tatatcagca atcgaattat gttatccgga tttagttctg cagagaaatg caggctatca
     2041 gacggatatt ccaaacggtt tgcttaaggc tcttggtttg tggtcttttg ataaaagcca
     2101 tcacaacgat gtgagggcag ctgcaaggtt gggattgttt tgggctcagc gcaacgacat
     2161 tgaggaggtg attgtggaca ttggcaatcg aattacgcaa atggcaagcg gaagcagtta
     2221 agcgtagcga ccgcgattgt cctggtatct ttttggaagc atacgggggt aggggtaaaa
     2281 ctatttgtgc ttttgaaatt gcaaagcata aagaagctaa gaaagtactt gttatcaata
     2341 accgattagc tatcctgaat ggttggaaca acacccatca agatttaggc tatgtaaatg
     2401 attttgagtt agaaatcatg acggatcgca gattgcagaa cagattagca agtggtgaat
     2461 ctatcgagtg tgatgtattt gtcatcgatg aatggcagaa tatgtcgagc gatgccaatg
     2521 tgaaagcata caagaaggtc aaacgcggct atacagtagg gctttctgca acgcctatca
     2581 ggaagaaagg gcagaatttc tacccgttag aaaaaacaat atttggaatg gctgagccta
     2641 atcaacgtga gaactggcaa ttagcccatg gtaagatgaa gtattccaag ttcagctatt
     2701 ctaaacaaga atgggatgac ttccgaaact atgaaagcta cgtggccaat ttaccaaatt
     2761 tcttccgttg ggaagatgtt gaggccattg aagaggcaga agaaaataac ggttttgagg
     2821 taatttttga accagtttgg tgcccacctg ctaatccgaa agagctggaa cagtttagaa
     2881 gtctaaacat cgttggtaaa gatggcaagt ttgcgatggc taagcaaact tttggtcgaa
     2941 agatttttga gaggtactta atccagacag ggtttgaaat tgactttccg aaattgaagg
     3001 cgatcaatgc agatacacct atgctaatac agcttgattt attgttggcc agtcatacag
     3061 aaatgctgat agtcagcaag tcgaagcaaa ttgtagaagt cattcgtgag cgtcaccctg
     3121 agattgggat ttggacggga gacaagaagg acgctctgga gcaaaccaat gtagtagcta
     3181 ccactcaagt acttggtgtc ggtgtggatg gcttgcagta taaatttaaa acgattgttg
     3241 tcctagatcc agtcaatcca tctgatggtg actacgacga ctaccgccag ctattatggc
     3301 gggtaacggg cagccgtcaa caacatgacg tgcgtgtcat tgaattttat ttttgaggag
     3361 acaaaatggc agaacataag gaatcgggta tctttattgt tttgcgttgc attcaggctg
     3421 acctaattgc tccaaaaggg cagtataact cttttggtaa gtatgcctat cgtagcgctg
     3481 aagatatcct ggaggctctc aagcctcttt tgaagaaata tgatgcctca atcgtactga
     3541 gcgacgaaat cgtccaggtt ggggagaggt actatgtaga ggctacagct accctttacg
     3601 caatgggtga atgtgtagga aacaaggctt acgctcgaga agacgagacc aaaaaaggta
     3661 tggacggggc acagattaca ggtgcagctt ctagctatgc tcgtaaatac gctttgaatg
     3721 ggcttttggc tattgatgac aataatgacg ctgatacaga tgcctatcat aatcagaata
     3781 atcaaagtgc tggtaaaact caaaagacta atcaaaaaca agcgagtcag caagagtcaa
     3841 cagcgaaagc tcctgctaaa aataatggtt ctaaaactat tactggagcg caagccaagg
     3901 ctatccgaac agaactcaaa aacatggcag aagctacagg aagtccagct gctgcaattg
     3961 gtaactggtt tatcggaaag atgggcgttg acaagccaga gaacattcct gcagagcgtt
     4021 tgaaagaggc acaacagatt atcgcagatg cgaaaaaagt gaaagggatt gaataaatga
     4081 ttaataatgt agtactagtt ggtcgtatga ccaaggacgc agagcttcga tacactccaa
     4141 gtcaggtggc agttgctacg tttacacttg ctgttaatcg cgcctttaag agccaaaatg
     4201 gtgagcgcga agcggatttc attaactgtg tgatctggcg tcagcaagct gaaaatttag
     4261 ctaactgggc gaaaaagggt gtcttgattg ggattacagg acgtattcag acccgtaact
     4321 acgaaaacca acaggggcag cgtgtgtatg taaccgaggt tgttgcagat aatttcaaaa
     4381 tgctggaata ccgccagcaa cagcagcaag aggattcatt cgataataac aatccaatgg
     4441 atattcaggc tgacgacttg ccattctaat aggaggtact gaatgggaat gaaggaatat
     4501 gctttggctt atcaaaaaaa aggattttct gtattgccca ttagtccaac tgggaagaag
     4561 ccgatgattg cttttgcgga taagccgcct atgactgccc aggaaattga agatttctgg
     4621 actcagtacc cagatagcaa tatcgctgtc cggacggata agtttttcgt cattgatatt
     4681 gacttacatg ggaaagctaa tggatttgag agtttggcca attgggaaca cttggatctt
     4741 atcactccaa ctctacaggc caaaacggcc agcggtggca aacatatctt ttatttcaaa
     4801 catccagatg tgtctatgac gcaaatgatt ggcttccttc cgggcgtcga cgtcaaagct
     4861 catcttaata actatgttct ggtggcaccg tctaaaactc ccaaaggtgt ttatgcctgg
     4921 gataaagaca agtcaaaaga ggatggcacc atggtcacag ctagtcgaaa gttagtcatg
     4981 gccatcaaac aagagtacaa caagaaaaat ccaggtagtg acctggataa tatctactat
     5041 caaattagca aaggtgctgg taagcggaac cggactacgg aactgtttga aatgattgtt
     5101 ttgggatttg gagaccaggg cgggcggaat gatactcttg caagatttgt cggtgggtta
     5161 ctgagtcggt cggtggatcc agaatgtatc ctgcggcttg cggaaacggc caataataat
     5221 tctgttgaac ccttgggcaa aagagaaatg agacggacaa tcgaatcgat gatcaaaaaa
     5281 cacatgaggg ggggtggcca caataggtga aattgttaat atttcaatca agcagttttc
     5341 acgacgaaaa aagaaaatcc tgagcgaaga aggtgaacag attgaagtag aatccattgt
     5401 ggcagacagc cctagaaatg tcttactggc gatgaaaagc gataacaagt tgaatgattt
     5461 tctccggcac aatgaattca ccggtgaaca tgagattgtg gaggatgtaa aactggacgc
     5521 cattcagctt cgacgtgggc agcttccatc tacttttgag tcatatctga gcgtctattt
     5581 ggaaaatcat ttcaaaacag tttttaaggc tggagcttta agagatggca ttgaagcttt
     5641 ttttgcagaa aaaacctaca atcctgttca ggaatacatg gagcacgctt atgaatcttg
     5701 ggatcacagg gagcggttag ctcaagtttt ccaaacgtgg ctaggtgctg aagacagtat
     5761 ctttgttcag cgtattgcgg tcatgttctt tgtcggtgca gtttcaaagg tgtttaaccc
     5821 ctgggtcaaa tttgactata cattggactt agtcggtggc caaggagcag gtaagaccac
     5881 cttcctgcag aaagttgcag tcgaatggta cactgattcg gcaaaagatt ttatggataa
     5941 ggataattat gaaatcatgc tgaagtctct gatcgtcaac gatgatgaga tggtggccag
     6001 cagaaagacc acttttgatg agctcaaggc atttgtaacc aaaactgaac tgtcgtttcg
     6061 taggtcttac ggtcgcagag ctgaaaaatt ccctaaaaac tttgtgattg ctaggacatc
     6121 gaacaaggtt gagtacctag gagacaaaac tggtgagcga cgctttctgc cagtgctggt
     6181 ggatgcagac cagcagttgg tcaaaccgtt tgatatgact gatcgggatg tgctccaact
     6241 ttggggtgag gcggtcgcta tttacaaaaa agggtttacg cttacttttg atgatgactt
     6301 cgaagacgaa ctggcggtct ataaggagcg gttcacttat aaagatgaag cggaatcaca
     6361 gatttacgat tatctggaca tgttagttcc tgatgagtgg gaagaaatgt cagtggttca
     6421 gcaacatcaa tatacctggg catactttaa taatggcagt tatcgtaatg agtcgggatt
     6481 tgtctatgaa ggtgttaaac tgcaagcgag tgtttccgcc aagcagattt tgaaaaacgt
     6541 atttgatatc gacagtgcaa gaggtgagag aattgctcgc aaaatcaagt tgattatgga
     6601 caatcatcaa gattgggaat accgaataaa gaagataaaa gggagaactg tcagggcata
     6661 ttttaagaaa aatatgcaaa atgaagtgat gtaacctttt aggctaaaaa aggctaaaaa
     6721 agcttaaaaa tggcgtttgg gttacatcag gttacatcat tgatgtaacc tgccgaaaat
     6781 ccattaataa caagggttta gggctatttt ttgagaaaaa ttcaaaaaaa gtgatgtaac
     6841 ctatctaaag ccttgatatg actggtttta tgaggtgtct attagtatgg ttacatcatt
     6901 tatataaaaa ctttaataag taaaaatagc aagtgctata aacgttgata ttatgggatt
     6961 cttgtttttt ataaatatat tttttgaaaa gtgatgtaac cttgtaacct cactaaaata
     7021 tgcaaaataa tgaataaaaa ggagagtaaa tgagttataa agttttagtt tattttgaca
     7081 atatgttgga cgaagaatat aagtttaaaa cagaaaaaga tgcatcgaaa tgccatgatc
     7141 aattgcgaag gaaataccaa ggtcagcgtt tatataaggt aaaaatggag gaggtggaag
     7201 aagaggtaat cataactaac ttcagggagg ttgatcatga ctaaagacga ctttttaaca
     7261 ggttttgtac ttatactttt agctgcttgc atttttgctg tgggatttgc gattgggcat
     7321 gattatagca gtgagcacta cgagcaaaaa atcacagatt tacaaataca gctggtaagc
     7381 acgcagcagc agcttaagca atctcgtgag caaaatcaga gccagactaa aaggattgcg
     7441 aatctgaccg ggaatggagg ataaaaaaca ctacatggaa ataaaatgtg gaaattgctt
     7501 agaattacta acagagttaa ctgatggatc aattgatatg gtgataacag acccgccata
     7561 taacatatca gtaaaaaata actttgctac aatggggcgg acaggtatag attttggtga
     7621 ttgggataaa ggtgcggact tattaagttg gattgatatt gcaagtcgaa aattaactaa
     7681 aaatggtgga atggtgatct ttaatgattg gaaaaattta ggagatattg caagacattg
     7741 cgaaaaaaca ggcttagcag taaaagatat tttccgttgg gtaaaagata accctatgcc
     7801 aagaaatcga gataggagat acattacaga tagcgagtac gggatatggg tcgtccgaaa
     7861 aaattccaag tgggtattta atcgtaaatc ggaaaaatat gataggccag aatatcgcta
     7921 tcctattgta tcaggagcag agaaaacaca gcaccctact caaaagccgg tagccctgat
     7981 gagggacatc attacgcgac acacaacaaa aagggctgtt gttttagacc cttttatggg
     8041 cagcggatca actggagtag cttgtctact gacggagaga gactttattg gatatgagct
     8101 aaataaagat tactttaata tcgcaaacaa aaggattgct gagttgactg ggaatggtgg
     8161 atgagatgtt aagagtattt gaagcttttg caggtattgg tacgcaacgc atggcattgc
     8221 gaaacctcgg gataccacac gaagtagtag ctattgccga gatcgacaaa tttgccatta
     8281 aaagttatga ggcaattcat ggcccagtaa ataatctagg tgatattagc aagattaatc
     8341 ctgacactat tcctgatcac gacttattta cttatagctt tccttgtcaa gacatttctg
     8401 tggcagggaa gcaagctggt cttgatattg atagcggtac acgctcagga ttgctctggg
     8461 aatgccaaaa agttatagtg gctaaaaaac cgaaatatct attaatggaa aatgtaaaaa
     8521 atctcgtagg caaaaagcat aagccaaatt ttgataaatg gcttgattgg ctagagagtc
     8581 aaggctacac gaatgactgg caagtgctaa atgcaaagga ttacggtgtc ccgcaaaata
     8641 gagagcgtgt gttttgtgtg tcgattttag gtgagcataa accttatatt ttcccagaaa
     8701 aacaggaatt gaccatcaga ctaaaggaca ttttggaaga tgatgttgat gaaaagtatt
     8761 atttaacaac aaacaaagca aatgaattat tggccacgat tgtccgagaa aatgatgttt
     8821 ctgaaagagt tgttgtagat agtacgataa aaaaaccaaa aataaaaaat gtaatgaacg
     8881 ctgtaatagg aagatatgat gcaggcatcc gaaatcaaca atcggttgga ggtgctgtca
     8941 ttgagcttat tgaataaaaa tgcaacaaaa aaaggctact tagtagccga tgatggggac
     9001 ggaatagata ctgcttatcc agatagcaaa acgaggaaag ggagagtgca aaaaaacatg
     9061 agccatacga taacgacaga tgatagtaag gcctttttga ttggcgcaag tcgtgggaga
     9121 gaccccgaaa acccaaacga taggtcagct ggaaaccaaa acctacaaca aagacttgaa
     9181 atcaacaaaa atggcacaag caatacaatt acaagtgtcc aaaaagataa ctatgcggtt
     9241 gaattcccag attaccgcat ccgcaagcta acaccgctag aatgttggcg gttgatgggg
     9301 tgtagtgatg aggattttga aaaagcacag tctgtcaata gcaatagtca gctttacaaa
     9361 caggcaggaa acgcaattgt ggttgatgtg ctagaggcaa tattaaagca attattttta
     9421 accgaggcgc aaaatgaaca ttgaagaagc gaagcaaaaa ttacataaca tggcatatag
     9481 agatttacaa actaagccgt atgatttgaa acttgctgat gttattcaga ttcttaatca
     9541 aattaaactc gacaaacctc aaccagaaat tccacagttt gtcgctgact acatagatga
     9601 tatgcacaaa aacgcacgta cattgagata cgcttttaaa tacatggaaa gtaacataaa
     9661 aatgcacaaa tggtgtgttt tcgaaaagca agaaacgttt gttaatgctt ttttatacgg
     9721 atatacaatt gaaaaagaga aactgtacac tgttgagata ccaaatccga aaaacggtat
     9781 tgcgcatagg cacataatgc tggttaagac aactgacgga agagtagttt tgtctgaagt
     9841 agtagactca cacatacatt tgagagatga tttaagactc accgagtcag aaatccgcaa
     9901 agacttcgat tgggcttgga gagaggagtt tcctaaagag gtgacggaat gatgaatgaa
     9961 agagaattaa ataaattgat gaattacgac aaaaagaaaa gtgatttaaa aaaacgcctg
    10021 attataggat ttaccctatt gccaatcagc atcgtattgt ctggatttgt tattaaatac
    10081 ggttggaata atattttgtc aacaattgat ggcgtcccac ctatcaattt accacaagcg
    10141 atagcaattg atgtgctagt aagttttatc attgccaaga caaacgcaga aggagatttt
    10201 gccacagaag ttggcagagc ttttatttcg ccgttaatga cgttgttatt gttttgggta
    10261 gtgactttgt ttatgtaatg tttagaggta acagatgact gaagaattag gagtgttgct
    10321 tgacaaggaa ggagttgaat acgtaaaaat ggtatttgat gatggctttg tctggacgat
    10381 acgcaaccca ctaaacgctg cgttgcttaa acgccaagat gcagagcagt tcccgcagtt
    10441 tacgtgggtg ccactgacag atttataacc ccacgcaatg gctctgtggg attacgtgcc
    10501 aggaaccacg ttgaaagcga cttagacacc ttcattttta tcagccttgc ggattgtcaa
    10561 aggttcgtaa ggtgtagacc gaaattaaac acagaaggat gtgatgacaa tctccttaca
    10621 cccaaaaaat ctaacgctgg ttaccggtca ccagctatta tccaaggcgc taatactgac
    10681 atcgtgcgcc tgtgtcaaaa taaaaaaagg aagagagggc ttttctccac aaaaaaagac
    10741 gtccatgcga acgcctcctt ggttatatct gttaacacca ttataccaca ctgagggggc
    10801 ttttatgacg ttttttcccg agattgatat ccaaaaaaca aaatccaatg ccaagcgtaa
    10861 attgaaagag tatccacgct ggcggcggat agctaacgat gtagatactc aaaaagttac
    10921 agctacttac tcatttgagc caaggcaacc tcatggagtc cctagcaagc ctgttgagag
    10981 actagcactt aatcgtgtat cagcggaaca ggaactggat gcgattgaga gagcggtcaa
    11041 cgggatattt gatccagagt atagattgat actgattgac aagtatttgc tcacatatcc
    11101 aaagactgat tgtgatattt atacaaaact tggttacgag aaaagtcagt actacaacat
    11161 gctagataat gctttaatgt ctttttctga actatacaaa gaggggatgt tgcttgtcga
    11221 aaaaatggaa aaaagctgga attaatatgg aataattatg tactttatat ataaatattc
    11281 atgttattat agtactatga aataacaaga agagataacc attttaccaa ctgactattt
    11341 atttagtcgc tgactttaac tacgatcaaa cttgttattt tatgtatgtg ggacgtgcgg
    11401 gttcgaatcc tgccgtctca atcagcgccc agaagaggcg cgaccccata cccctttaaa
    11461 ggcagacacg ttctgatgtg tgggttttta tgattaaccg caagttcaaa aacaagggtc
    11521 gcaaccttgc ttgtggttag tagggacaac ggttgtaagt cggttcgatt ccgactgttc
    11581 ctgtgctagt catcacatcg tgatggcttt ttattatgca aaaaagaacc actaagtggc
    11641 tcttatgctt gtagttttaa ttcaagtgcc tctgtgagga cttgcgagaa attgagattt
    11701 tcatcttcgg ctgctttgtt taaccactca gggatagtca cgttcttacg tactttttta
    11761 gagtggtatt ttttcatgta ggcaatcata tcgatgccga ttaaagcaat atcagaatca
    11821 cgatactgtt cttttaagtc ggaaacggag ctagcctttg gatagtcagt atagtcttca
    11881 agagcaaagc ctaagacttc gacagccatt tcgtaagctt cttgaaagtc tttaccttga
    11941 gtaattgctt caggtacatc tggaaatgta accatgatat agtctgtgtc ttgtgtgaat
    12001 gtagctggat agattaacat aatgattctc cttcgatcac tgtgagataa gcaaaccatc
    12061 tggcaagcgg attattttaa acccgcctgc tttagaatgg tatcttcaag gccttttccg
    12121 aggtctttgt tgtgtagagg aacaatggtt tgatgtccgt tattatctcg gaattttttg
    12181 tgacttccgt tttgactgac ttcatagaac ccattctttt ttagcagttt tatcatctgc
    12241 tttggggtca ttggcatatt gcttacctca ctttctatac ttatattata cacgcaataa
    12301 acatggttgt caataggtat gcgcaaaaaa tgcgtatttt tgttttctat tttttattat
    12361 ggaggttagg gtatgaggcc gcagaagtta acaattgcgg gtggcagacg aacgactgtt
    12421 gactacgatg ataggtcagc tgagtatcgt gactataatc gtaacagatg gaagtatgat
    12481 aggaagacta agcagtttta taactctaag atttggagag agacaagtaa gcaagtctta
    12541 ttgcaaagtg attatatctg tgcaatgtgt ggtggagaag caacgatgac tgatcacatt
    12601 gtctcagtta agaaagattg gaataaaaga ttagattgga ataacttgca agcaagttgt
    12661 aaagcttgta acgattgtaa agcaataaga gagagacgga aaacctaaac gtacataaaa
    12721 agtaacatac gcaatcattg ttcgggaaat accccgccta ttttttaacg gggctatatt
    12781 gttcggaaac ttaagaacgc gcccttttct gtgcaaaaaa atcccttttt gaaatttttg
    12841 aaactgtaaa gtttgtgtaa aggaggtctt atgggaagaa atttaaagct agttgaaacg
    12901 acaaaaaagc atcttacgaa agaagaaaaa atagtgcgag aaaccgcgca aaataaggcg
    12961 tctgacggtc ttaaaaagtt gcaaaagaca cctcctgaac actttaataa tgtagctaag
    13021 tacgagtata ggagaatcat agaagacctc caaaacctac ccctaagaaa tctcgataga
    13081 gggctattag agttatattg cacatggtat gctatctaca aagaaacaag tagaaaacta
    13141 gatgaggttg gttattttac gaatgatcca gacaaaggca ttattcctag tccgcttatt
    13201 ttaacattgg aaaaagccac tgcgaatatt agaagtagtg ccagtcaatt aggactaacg
    13261 gtagatagtc gcatgaagat gtttattccg aaggaagaag aaaaacctaa gagtatattt
    13321 gataaatttg gaggatagag agaaaggggg tcatgacaat agaatacgat tattcagcaa
    13381 tcggcgacat ctataaagat gacgcttttt attatgcaaa aaaggtcgtt gatgaagaga
    13441 ttaaagcaag taagaaggtc tttaaagctt gtctaagaca tttgaatgac cttaaaaaaa
    13501 tagatgatga taattttaaa tttatctatt taccaaaaaa agcaattgac cccataattt
    13561 ttattgagct attgccagac gttaagacgg gaaagcctta tcctttagcg atgtttcaga
    13621 agtttattat cgggaattta tacggatggc gaaagaaaac agatcattcc ttaagacgct
    13681 ttagaaaagc tatgatttcg gttgctcgta aaaatggcaa aacaattctg atagctggta
    13741 tcttgcttta tgaatttttg tttgggcata atccatctat gagtagacaa ttgttttgta
    13801 cagctaatga ccgtacacag gctaaaattg cttgggacat ggcaaagaag caactctcat
    13861 ctttaagagc aaaggacgct gatgtcagaa aagccacgaa aattgttcgt gatgagctga
    13921 aaaacttaca tgatgaatct tatattaggg ctcttagtcg agatactggg gcagtcgatg
    13981 ggttcgagcc ttacgttggc gttttagatg agtttgcggc atcaaagaca aacgaaatgt
    14041 tagagctttt agaatccggt caaggtcagc ttgataatcc gtttatcttg attatctcaa
    14101 cagctggtat ggatttgaat gtccccatgc acacaattga gtatccgtac atcactaaaa
    14161 ttttagacga agaaattgta gatgatggct attttggata tgtcgcagag caagacaacg
    14221 aaggtgaaat taaagatgaa tcaaattgga taaaatcaaa tccaatcctc gaggttgaag
    14281 ctttgcacga taagctaatg gattacctga gaacgcgtcg tagagtgtct cttgaaacag
    14341 gtgaaattaa caaggtactt atcaaaaact ttaacatgtg gcggcagtcg agtgaggaat
    14401 catatattga taagcaatct tgggaacttg ctcgtattga taaacccgac acacataaac
    14461 gaagggtctg gctaggtgtg gacgtcggtc gtgttagtga cttatttgct attacaccag
    14521 ttattatgat ggacgatttt tggtatattg acagtttttc ttttgttgcg acaaagtatg
    14581 ggttaacggc taaagaaaag cgtgatggtg tgtcttacag taatttagaa cgtcaaggct
    14641 attgcgagat aacaacatta gaaagtgggg ttattgatga tgagagagtt ttagaaaaaa
    14701 tagaggagat ggtctattcg aatgactggg aagttaacgg aatctgtttt gacccttacc
    14761 aatttggaac gctgcttacg atgattgaga aaaggcaccc agaatggcct ctcatagagg
    14821 tttcgcaaac gacaatggtt ttgaacatgc caacaaagca atttcgtgat gatctcaaga
    14881 atggcaaaat aaagcactct ggcaatccat tgctaacaat ggctgttaat aacgcttata
    14941 tcaagactga taacaatggc atgaggattg ataagaataa gaatagcaat aagatagacc
    15001 ctctggacgc tgctttagac gggtatgcag tttgttactt agagccattt gacggctctg
    15061 gttactggac aagtgagaaa attttaggag gagagacact gttttgattg gttttatttt
    15121 aaaaaacata catacattaa tcttgttagc tggactaggt ttattgatgt atgggttgtt
    15181 tttgtttggt gataaagttg gttttatcgc tagtggtctt attttaattt ttttagctat
    15241 ctatgtagat agcgtaggag gaaaacatga ataaacgcat taagaaaaaa cgtaaattgg
    15301 aaacagcggt tgtgatgctt gttgcagaaa atgctatgca agctgaagca ctcaggaatc
    15361 aaaacagaca aattgcagag ctgagatcga ttatacaaca aaacgcccaa gcgacaaata
    15421 gagagtttgc agcagttaaa tcagcgacgc tagacaacca agcagccatt aagaaaattg
    15481 gggatgaggt ttattatatc aagcaaaatt ataagcgcaa gtggcggaaa tagatgttaa
    15541 tggtttagaa aggaggtgag aaatcgatga gtttttttca acctttgggc agttcaaagg
    15601 tgtcctatga tgactatgta tcatctgttt tagctggcga tgtctcccaa aaatacttag
    15661 gagtgtcggc tttgaagaat agcgatattt taacagcaac gtctattata gctggggata
    15721 ttgctaggtt tccgcttgtt aaaaaggatg ttaatgggga cattatccat gatgaggata
    15781 ttaattatct tttaaatgtt aaatccacaa aaaatgcgag cgctaggacc tggaagtttg
    15841 ctatggcagt aaatgccatt ttgactggta attctttttc gcgtattttg agagatccaa
    15901 agactaacca agctttgcaa ttccaatttt acaggccgtc agaaacgact gttgaggaga
    15961 cagataacca cgagatagtt tatacgttta ctgatatgtt gacagcaaaa caggttaaat
    16021 gttttgccca tgacgttatc cactggaagt tttttagtca cgatacaatt ttgggaaggt
    16081 ccccgctact gtctttaggt gatgagattg atttgcaaac cggcggcatc aataccttaa
    16141 ttaaattctt caaagatggt ttttctagtg gcatcttaaa aatgaaaggt gctcatataa
    16201 gcggtgaagc acgtaagaga gccagagttg aatttgaaaa aatgcgcgag ggtgcaattg
    16261 gtggtagtcc tttagtattc gatgatacgc aagaatacac gccgcttgaa atcgatacta
    16321 acgtattgca attaattaca agtaacaatt tttcaacggc gcaaatcgca aaagctttgc
    16381 gggttcccag ctacaagctt ggtgttaata gtccaaatca atctgttgcc cagttgatgg
    16441 aagattatgt cacgaatgat ttgccatttt attttgatgc tatcacaagt gagttaggac
    16501 ttaagacgct aagtgataag gataggcgtt tgtatcgtat cgagtttgat acacgaagcg
    16561 tcacaggtcg caatgttgat gagattgtca aattggttaa taaccaaatc ttgacgccta
    16621 accaaggcct cgtagagctt ggtaagcaaa aatcaacaga tccaaacatg gataggtacc
    16681 agtctagtct aaactacgtc tttttagaca aaaaagaaga atatcaagac aaggttggta
    16741 tcaaagggaa aggaggtgag gtaaatgcca aagaggataa atcttaaagg accactaatt
    16801 gcaaataact ctcaagaagt ttacgactat tacggaatgg aagcagcaag tgctaaaagt
    16861 atcattgagc aatttcctga agataatagc gatattgttt tggaagttaa ttcaaacggt
    16921 ggacttgtga cagttgggag tgaaatctat accgctttac gaaattacaa aggaaaagta
    16981 actgcagaaa ttactggcat ggctgcaagt gcagcatctg tggctgttat gggtgcggat
    17041 aaggttgtca tgagtcctac agctcaaatg atggtgcata aagcactctt taaatgggtg
    17101 tctggtaata gtgatgacct agacaaagct tctaatgcct taaaatcaag tgataaagct
    17161 attgtgagtg cctatgtcgc aaaaacaggg ttatcagaag atgcaatcat ggatttaatg
    17221 cgaaatgaaa cgtttatgtc cgctcaagat gccgtagaaa aaggttttgc ggacgaagtt
    17281 atgtcttttg aagcagttgc tagcattgat aattccatgt tgccgcaagc tgttattgat
    17341 gactattaca gaagtaggaa caaacgaaaa caagagatta gcaacatgtt actagaaatt
    17401 gaaaaagaag aaattttacg agggctataa gctctttttt tattggagga atttatgttc
    17461 gaagaaaaaa tcaaagaaat taaagcgaat atcgctaatt taaaccaagc tattgctact
    17521 aaaacaacag aagtaaaaaa tgctttggaa tcagatgacc ttgaaactgc tcgctcaatt
    17581 aaagcagaaa ttgaagaagc taaagcaaac ctagcagaag cagaaaatga cttgaaattg
    17641 tatgaagcta gcattgaaaa aggcggtgca gaaaatactg gaggaaaaga agtgccacaa
    17701 gaaactaaaa cataccgcga aagcgttaac gaatttattc gttcaaaagg aacagtaact
    17761 aatgaagctt tgcgttttga aggaaaagat gaagttctta ttccgcttaa tcagacaaca
    17821 ccagtcgctc ctgacacaga tggaattaaa aagacagacg tgaaacctgt ttctagcgaa
    17881 gaaattctat acacaccagc tcgtgaagtt aagacagttg ttgatttgaa acaatttact
    17941 agcatccacc cagctaagaa agcatctggt aaatggccgg tattgcaacg tgctacagaa
    18001 aaaatggtaa gcgttgaaga attggaaaaa aatccaaaac taggcaaacc acaatttaaa
    18061 aacgtggagt gggaagttaa aacttatcgt ggagctatcc cgttatccca agagtcaatt
    18121 gatgatgcag atgtagattt ggttggtatt gttgctgaaa caatcggtca aatgaaagtt
    18181 aatacaacta atgatgcaat tgctaaagtc ctaaaaacat ttgaggctaa agctggtgtc
    18241 aaaacattag atgacatcaa aaaaatccta aatgtagatt tagatccagc ttacaatgtg
    18301 tcatttattg tatctcaaag cttttaccag tccatggata ctttaaaaga cgaaaatggc
    18361 cgttacctac ttcaagattc aatcacttct gcgtctggca aagtgtttct tggaaaaccg
    18421 gtatttgtcc tatctgatga cgtaattggt aaagactcag cttttgtcgg agattttaag
    18481 cgcggcgtgt tatttgctga tcgtaaagat ttagggcttc gttgggcaga taacgaaatt
    18541 tacggtcaat acttgcaagc tgtccttcgc tttggtgtcg ctaaggtaga tgacaaagct
    18601 ggatactatg tgacattcaa accagaacaa ttgccctcat aaggccactg aagaagtggc
    18661 gaaaccaact agcaaaagca ctgtcgagga gattaagcgc tatttaacaa gcaagggaat
    18721 tgactttaat gggaaaacat taaaatctga tttattaaaa cttgcaggcg ttgaagaggt
    18781 atagctatgg ctgtatcaaa agagttatta gacagtgtaa aactctattg taaaattgac
    18841 tttgattttg atgacgacat catcaaagaa atgattgaat ctgctcaaga acaaatctgt
    18901 tttgcaatag aagacggttc tactcctgaa aagttcaaag gtcacgctaa atttaattta
    18961 gctgtcaaaa agcaagtcaa ggaagagtat gaccatcgcg gtttgtctgc ggatagtttt
    19021 cgctatccgt tggcaaatgg tgttttaaac attatccatc aattgcgatt gagaggtgat
    19081 gattcgtgat tacacgcaag atgaacgtca ggataacgat ttttagccaa tcaggcgggc
    19141 aaaatgaaga tggtgaagta gtatctgctg tcagaaagga cttgtatact tgttgggcag
    19201 aagtgctaaa aacgcagttg agagatttta attatcaatc aaagtatcaa aacgctagca
    19261 atttgccaac aaataaggat actaaggttt ttttaattag gtataaccct gaattatcta
    19321 tagataacac gatgtttgtt gagtttggca agcgcattta taagatagat aaaatcgaat
    19381 ctgacgaatc tggcaaagat attatcatga taagtggagt aagcatgtca tgacaaaagg
    19441 tttagatgaa atattggcta atctgacaaa gcttgaagta aaagcaccaa aaaccgcaaa
    19501 agcagcagta actgaagttg ccaaagaatt tgaaaaagca cttaaagcaa atacccctgt
    19561 ttatgagatt gaaacagatg agcggctaca ggaagatacc gttatcagtg gttttaaagg
    19621 agctaatgtt ggaattgtat ccaaggaaat tggctatggc aaagcgactg gttggcgtgc
    19681 gcactatcct aacgatggga ccatttacca acgcggacaa gactttaagg aaaaaaccat
    19741 caatcagatg acaccaaaag ctaaacaaat ctacgcagca aaagttaagg agggactagg
    19801 actttgattg ctgaaacagc agcttataaa ttattaagta acgataagac gctaaatgag
    19861 ttgttggata ggctcagagg cggtcctttt aaaaatgggt ttaagcaagg catatttact
    19921 tatgatattc cagataaccc agttgacttg cgtaaggtag atttagcgcc ttttatgcga
    19981 atcaacacaa cattagacgg tcctgctgat tatgcagatg atgagatact gtgtaacgag
    20041 caacggatca ccatcaattt ttggtgcaaa acagcttctg aagctgacca aattagcaaa
    20101 tgtatagatg atattttaaa aaaaggcggt tttgaaagat acaccgcaaa cgaaaaacca
    20161 agatataaag atagcgatat tgacttactg ataaatgtaa ggaaataccg ctattttgat
    20221 ttttattaaa agaaagagga aaaaatggga aaagtaaaat ttggactacg tgacttccaa
    20281 tacgcagtac tcggagatga tgatcaatta aaaacaaaaa cgggaggtat caaatcacta
    20341 cctggcatga aatcagcaaa gcttgatatt acaaacgaat tagtgacggt agctgctgat
    20401 gatggtccat acgtagtttt atctggaggt attacagaaa caaaacttga aatcgaggtg
    20461 ttagacttaa catctgacgc acgaaaagac ttcttcggaa ttaaggaaga agacggaatc
    20521 gaaaaataca ataaggagct gacccctaac gatgttgctt gtatgttccg aacaagcgat
    20581 gaaaacggga aagccatctg gattggattg ctaaaaggta agtttaacat tccgggtatg
    20641 gaaatgcaga ctaaagaggg agcgccagac cctaaatctg atactgtaac aggcaacttt
    20701 gtgtctcgtg gaaaagaagg agatgttatt gttatcggtc gcgaaagtgc tagtggtttt
    20761 aaattagaga agtttaaaga atttgtgttt gctggtgcga cagatattaa aaaaggcgaa
    20821 aacttcgaaa tgtaacaatc aggttggatt taaaatccaa ccttttattt ttgataagga
    20881 gtagatatgt acgaaattac cttaaaaaaa ggtggtgtag ataaagtttt ttcaaaggac
    20941 tttattaacg ttgaggataa tttgttggct gttgagcatc aagttagaca aagcgctgtg
    21001 tttagcgatg agaaaagacg cttagattct aaagcgcata gaaaacttaa cgaatcttac
    21061 ttgcaaatgt ttgttgatat gtacgcaggt caatttacag tcgatgattt aaagcaatct
    21121 gacatgagtg ttttaaatac acttaatgac ctgtacattg cagcactcgg tggagagcaa
    21181 gaggaagacg aaagcgaaaa aaaggaacaa taaccccaca agaggctaaa gaaaacttac
    21241 tcttgtggat acagagcctt ttgaaaaacg gttataccat tttagatatt aaaaaaatgc
    21301 gcttatctga tattgaattg atggtacaag cgctagaaat tgaaactgtc gaaaaagaag
    21361 aagtgattga aacgaccttg gataaggcat tcccattcct tttcggctag aaaggaggat
    21421 aaatggggaa tataggtgat ttagtagcaa cggctacact agacatatca ccatttatgt
    21481 caaacacaag aaacctaaaa acctacatga aaggcttaga taactcgtta aaagcagttg
    21541 aaaagagctt tcaagggcat ggcgggcgga tcaaaggtct taaagcggtc tatgctgaaa
    21601 caggtagtgc attaaaaggt taccaagaat tactaaaaac tcagtcgcaa aaatatagcg
    21661 acctaaaaaa agagataggt gatgttaata acgctactgc tgagcaaaag caaaaattga
    21721 ttggcgctaa atcagccatg ttggagactg ctgcgaaagt cacagaattg caaaacagat
    21781 tacgatcgtt agccactgaa actagcgttt ttacaagatt tggtaaagct gctgaaagaa
    21841 tcggcgggaa gatgaagtca ttcggcgatt cggtagctgg agttgatgct gcatttacaa
    21901 gaggagtcac cgctccgatt gtagcgggcg ctggttatgc tattaaagca gctgttgact
    21961 atgaaactgc atttgctggt gttaaaaaga cagttgatga gacggcgaca gtatcttatg
    22021 cgaagctatc acagggtatt agacaaatgg ccaaagagtt gccagccagt gctgttgaaa
    22081 tcgctcatgt cgcggaggcg gcaggtcaat taggagttaa gacaggagat attcttagtt
    22141 tctctcgtac aatgatttat ttaggagagt ccaccaattt atcggcagaa gaagcggcga
    22201 cgtctattgc taaaattgca aacattacag gtctggcttc atcggagtat tctcgctttg
    22261 gtagtgctgt tgtcgcgttg ggtaataact tcgcaacaac tgaaagagac atcgtagcga
    22321 tgactaatcg cattgctgcg tctggtaagc ttgcgggatt aaccaatcaa gagatgttag
    22381 ctttagcaac agcaatgtca agcgttggta tagaggcaga agctggtggt acagcaatga
    22441 ctcaatcatt gtcagctatt gaacgtgcag ttgcatctgg aggagataat ttaaataaat
    22501 ttgctcaaat tgccaatatg tcatctgctg atttcgcgag agcatggaaa gagaagccaa
    22561 ttgttgcatt gcaagagttt attaaggggc ttggccagct tgataaaaaa ggtgaaagtg
    22621 ctacaaaagt gcttgacgac ctcggattaa gcggtatccg ccagtctaac atgttgaaat
    22681 ctttaggatt agcatctgag actttaggca aggctctaga tacctcaaac aaagcttggc
    22741 aagaaaacac tgctttaact gacgaagcta ataaacgcta tgagacaaca gagtctaagc
    22801 taaaaatgct taagaatgaa gttaatgatg tagctattga atttggtggc cctttggttg
    22861 acgctctaag aaatgggctc gaagcaggaa aaccaattat tcaaatggca gcagatttag
    22921 ctaagcaatt taactcgctt gacaaagagc aacaacaaca aattgttaag tgggggctta
    22981 ttgcagccgc agctggtcca gctttatcta tctttggtaa aggcgttggc attatcggag
    23041 gaaccattca agctatgggc aaaatgagtc gagggttagg cactttatca ggctggttga
    23101 ggacattcag aactggagca gtagcagcta gtgcaggagc cgaagctgcc acagcttcta
    23161 tgggcggaat ggctggcgcg gttgccttat taagtaatcc tgtaacttgg ggtgtgctgt
    23221 taggtggtgc agccattgtg ggtataggtt taattgctga tagcatgtat aaagcccaaa
    23281 aacgcacaga agagtgggga attaaagtga gtcaagtgca agccaatgaa ttgcaaagat
    23341 ttaaaaacaa agttgacgaa gctaacctcg caatgacaac atttggagtc aggagtgcta
    23401 ataatctcga taaaatcaag acatctttta aagcactggc agacgaaata gaggctttac
    23461 aaaacaaaaa acttaagaag gatctaaaac tagccgaaaa gttaggtctt agtcaagaga
    23521 caatcgagga gattaggcgt caagctgacc aaactgtggc aacagttaga ggtatgtctg
    23581 acaaagttgt agacatttac cgaagagcca aagaagaaag aagaagtttg actgaagaag
    23641 aaaagactgt tgtcactaaa aatttgaatg acatgatcca gactgagtta tctttgatga
    23701 actactctaa aaaagaaaag atcgccattt tgaaggcgat gaatggagag attgaaacgc
    23761 ttaattatga gcaacttaaa aaagctcaag aagttgctca aaagatgata gagagcgaaa
    23821 acaagactta taaaaagaga cgaagtaatc tcaaagaaat gtatgacaat atcaaaggag
    23881 actctgaaac tgctgtgaga gccagagagg agattcacag acagctggag accttggaag
    23941 atagtcatac agcaaaaatg gagagtttag gagaaagata cttaaaaatt cgtaaaaaac
    24001 ttctggtaga cccagcttta gatccacgag ttaagcaggc tatgattgat agcttagaca
    24061 aggaatttga aaaattagga ttatctttcg aaaagttatc taaaaggagt gaagaggcta
    24121 gctctaagac caaaataagc atgcaagaca tgacaagctc attcagagca tcgataggcg
    24181 aagccattag ttcattgcaa gggtgggaca atcttacgcc gcaggaaaaa caattgttga
    24241 tagatgggaa taaggctgtc agtgagatcc taaatagtaa aactttactt gagcaatggc
    24301 aagcgctgac ccctcagcaa aaagaactgt tagctaaaaa tctaactcaa gacccaacgt
    24361 tatcagctca acaagcaatc gataatgtta agcagcgagt gccagctgat gttaaagcct
    24421 cggacaagac tgctccagat gtcgcttctg ccgatagagc cgttaacagg cctaagcaaa
    24481 aaggtccagc tattattaga gcacaggata atgctagtag tgttgctagt ggagttattg
    24541 ggtggctaaa tagtatacct cgtacagtga catcgacaat aactacaatt gttcgtaaaa
    24601 taaccggcca taagacggga actgattacc accctggcgg tttagcgatg gttaatgacc
    24661 aaaaaggtcc tttgtatagg gaattgatca ctttaccgac gggagaatcc tttatcccgg
    24721 aaggaagaaa tgtcattctt cctttgccaa gggggtcaaa agttcttaga gcaagtcgta
    24781 caaaacaatt attctcgcat tatgcaaacg gaataggttt taatgatacc aaaatcgcta
    24841 gcttaacaac tcgtcttaaa tctgtgcaag ataaaggaca agtgattgtc aataccgatc
    24901 ctcaacttgc ggagttgatt aaactactta aagatagaga taacagaaat gtcacaaaca
    24961 actacacact taacgctaca aacaggagta actctgatga tatgtttaat caagaaaaca
    25021 tgagacgtct cctaagagaa cttgcatact atacaaatgg agagaaaggg aggttggctt
    25081 aatgcgatac attgaattta atggtaagaa aagtgatagc tttggtcttt tgctagagcg
    25141 tgaacgatct attaagtcaa cgagtaacga tgttgattta atagaagtcg atggacgcga
    25201 cggtgtactc ttaaaagaca atggtcgttt gaaagctatt gagcaagact ttcctttttc
    25261 tttggttggt gacgtggctg tcaatcagca aaaaataagt gaatggttac atgtcaaggg
    25321 ttggcacgac ttagctttgt cttgggacaa ggactatatc tatcgggcta gtgttgtcaa
    25381 tctttttgaa atagacgaga tacttaagca atttggtaga ttaaaggtta atttcttaat
    25441 ccaccctatc aaatacctaa aaactggtaa gcaagaggtg tctctcgtta atggtggcac
    25501 tctacaaaac cttggtaatg tgcagtctaa acctatctta aaaatcaaag ggacaggcaa
    25561 cggtgtttta accattaatg gttttgagac gggcctcgaa aacgtccaag gagagctcat
    25621 catagatatg gagaggcacc ttgtctataa agatatcctg tctgcttggg ataacattgt
    25681 gcggacagaa cgccaccgca tgccactatt tgatattggt caaaacaaaa tctcatggac
    25741 tggtaacttt actatcaccg cagtgccaaa ctggggggtt aaagtatgat accagtttta
    25801 tacgaggcca aagaaaccaa atttaggact tttggccttg gtgagatcgc agacgcttat
    25861 gaggtaagag ttactcgtga gcgcaacggt aattactcgc tatatatcaa atatccactt
    25921 gatggtgttt ttgcctcggt ctttaaggag gagcttaaga ttaagtctga tgccggccga
    25981 aggacaaaat ggcaaacttt tgagatcaat cgggtgttgc gaaacagtaa agaccacatc
    26041 gagatttttg caaggcatat ctcaatgcgc acacaggaca tcgctttaaa accatttgtg
    26101 agcgggtcta gcattgacgc agagtcggca ctggaggttt ggcgggataa tcttgtcggt
    26161 gatgatacct ttgatgttaa aagcgacatt ttaacactag gcagctttaa ctgggaagtt
    26221 gacaagatag gcaatgcaag aggcgctctc gggggtgttg ctggctctat cttagatgtt
    26281 tacggtggtg agtacgagtt tgacaatcgc acaatcatct tacataaaca aatggggcgt
    26341 aaggccccta cggttttgga gtatggccgc aatatcgtca gcgtggaaga ggagcgtttg
    26401 cttgatggca attatacctc aatctatcct tacgtaagat atacgccaca accaaagccg
    26461 caagaggaag cctctggtaa gccgcacatc ggtgagcagg agcagcccga agaacaactg
    26521 gtgacgctgc ctgaatttat cctagatggt cagtatcttg acttatatgc ccaacgcaga
    26581 atacagatgg ttgatttatc tagtcatttt aatgatgaca aaaaagagcc gacagtcgaa
    26641 gaaatcagaa agctggctca gaaatatctt aaagataaca atgttggcgc acctaaaatc
    26701 agtatagagg ttgattatat cgacctgtca cagacgcttg actatcaaga ttttagagtt
    26761 atggaggagg tcgagctttg cgatattgta ccgctttact atccaaagtt tggtatcaca
    26821 accgagaccg aaaaagtcgt tgagattgtc tatgacgtct atacagatag caatcacaca
    26881 ataaagcttg gcacgattgg ccaatctatc tctaagagtc tgacaggtgg tgttacgcag
    26941 cggattgaga cgctggaaaa caaccaaaag gttattacta ataatcaaca gcaatttgag
    27001 cttaatttac ccaaatacct caacgatcta aacggtacca agatatggta cgaaaaacca
    27061 gatgacaacg ttgagcacaa gataggcgat ttttggtttg agaaaaacgg taaatatcag
    27121 cgtacctggg tttgggacgg gaatcaatgg gtaaaaatca ttgatactga ggatttaaat
    27181 cctaatcagc gagcttttga tgaggctatg gccgagattg aaaagctaaa gcagcaccag
    27241 cgagaactcg acgaacgcaa ccaaaaagag ctcgaagagt ttagagaaac cctcaaaaat
    27301 ctgtcgctgc ccgaggaagc catcaaaaag ataacagagg ctatcaaagt tgatgatata
    27361 ccgtcaatta aacagtcgtt tgacgacctc aaaaacaaag tcagtgagac gagcgagacc
    27421 gcacgattaa acgctgagat tatcgggaca gatggcaaga cccgctacaa caaaaactta
    27481 ttggttggcg accctaatcg tgtcaaaaaa attgatgagg attttatcga ggtagaagcc
    27541 aacgatggtg gctttagacg cggtgagact tacaccatca gctttagcca aacttgcgag
    27601 ctgctcaaaa aagtggctat cacgttgacg caagctaata ataagggtgt taaattagtg
    27661 ttgataccga ctaaagctaa gatggaggcg cagaccttta atctaagtaa agataaggag
    27721 gtcatcagcg tctatccttt gagctacagg gctgttttga caggtgactg gtataaatct
    27781 aagcagattg agttaaatgc ggcagaggtc caaaatttgg ctctggagat gtcttataga
    27841 gacgtagttg atagcaataa tgctagtttg attttggatt ggtccccaaa tccagatgtt
    27901 atttttgatg gaaatggagg tagttaatgt cagagactat atcagctata gttgtgcata
    27961 aaagcatgac aaaaaacgag tgggagtcta gtgacatcat tttgccacaa ggccagctcg
    28021 tctatgagtc tgacacaggc catagtaaat ttggcgacgg taaaaataga tatgcagatt
    28081 tgatctatca aggtgggcca cctggaccac aaggtccaca aggactaagt ggcgaccgcg
    28141 gtcccatagg acaaacgggt ccacaaggta aacaaggtgt cagtgtccaa agtgcatcag
    28201 tagatagtga gggctattta actgttttgt tagataacgg acagtccttt aaatctgata
    28261 gcagcttaaa aggatctaaa ggagatactg gtcctaaagg tgctgacggt aaaatgactt
    28321 ttgagcaatt gacgccagag caaaagcaac aactaaaagg cgacaaaggt gatccaggtc
    28381 ctaaagggga cattggtcct agaggcgcaa cggggcccca aggtcctaaa ggagagccag
    28441 ggataaatgg tatggacggt ccaagaggtg caacaggtcc ccgaggactg caaggcccac
    28501 taggaaaaga tgcggttttg cccgacgacg ttgttagacg tggtgagcta gcagcttatc
    28561 tgctacggtc ggaatacaaa gctaaaggct caggatcagg tctaagctat aaagttgtca
    28621 cccagtctga gtacgatgat ctgtatgatt acaacgacaa cgagttgatc ctcgtgacgg
    28681 agggttgaca tggcatataa gctttatact aaggctgatg ttggtgacaa catgttgctt
    28741 gtcgctggcc gccctctgcc cgatgacaca aagcgcctaa aaatccagcg tgagacgtta
    28801 gatgtgttaa ctattaccca ttatggctct tacgacatgg tgcacctcaa gtcgacagtc
    28861 aaaaaggcgt atagcaaaaa tacagttgtt actcctgtat ctgcagctgc tagcaagccc
    28921 aaagctaagc caaagcacgt tttaaacttt gctaaggcta ataaggttta tataggcagc
    28981 actcgtgtaa tagcagtgta tttgggtgat cgcctgattt ggtctgacaa acatagcagc
    29041 gggaccaaaa ctgtctcggt tgtggggagt cttgatatca gacaatcaca aaaaatgctg
    29101 tatttgtact taatagcgcc agacgtcgca gatgttaaaa gcaagcgcat taaatcgata
    29161 gcgatcaatg gcgttaaact gtcaagcact gcacaaatca gctttgaggg cagcagctat
    29221 tattaccttg tgacaatcaa gcaagttgct aacatcaaag agatcaaaaa tatagcgtca
    29281 aaaaacaaaa tcacgctaga gttttaggag gtaacaattg agcagagacc caacaataac
    29341 attagacgag tcaaacctcg tcataggaca agatggccgc atgcactaca cgtttgtagc
    29401 gcaagatgat aaccaaaaag tcagactggc tagtaactgt ctaggcacag cgcattttaa
    29461 ccagctgatg attgagcgag gaggccaagc gacggactac gttgcgcccg ttgttgttga
    29521 gggcagcggc aagccaacgg gcttatttaa agatcttaaa gagcttagtc ttgagctcac
    29581 agatactgct aattcccagt tgtggtcaaa aatcaagctg acgacaaacg gcatgttacg
    29641 tgagtatcat cgtgatcata ttaaaacaga aattattgag agcgccgatg gtattgccaa
    29701 gcggattgcc gatgacactg gccaaaagct ggcactaatc aatgagacca tcaacggtat
    29761 cagacgcgag taccaagacg cagatagaca gctatccgcg agctaccaag caggcattga
    29821 tggcctaaaa actcaactgg ccaatgataa aatcggtcta caagctgaga ttaagctgtc
    29881 agctcaaggc ttgtcacaaa aatacgatga ccagatacgg cagctatact ctaaaatcac
    29941 cacaacctca tcaggtacca cagaggccta cgaaaacaag cttgagggct tgcgggcaga
    30001 gtttacaaga tctaaccaag gcctgcgcac tgagttagag tcgcagatta gcgggttaag
    30061 gtctgtgcag cagtcaactg ccagccaaat ctcacaagag atcaaggacc ggacaggcgc
    30121 tgtcagtcgg gtgcaacagg acttaaatag ctatcaacgt cgattagcaa gtgctgaggg
    30181 caattacagc agtcttttgc agacagttaa aggtctacaa tcaactgtta gcgatcccaa
    30241 aggtaaaatc caatcac
//
LOCUS       DARYMD010000027        29896 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYMD010000027 DARYMD010000000
VERSION     DARYMD010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29896
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            336..662
                     /locus_tag="TU818_001124"
     CDS             336..662
                     /locus_tag="TU818_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL0923946.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKATLDGIIEGR
                     LRHDKR"
     gene            649..1074
                     /locus_tag="TU818_001125"
     CDS             649..1074
                     /locus_tag="TU818_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923947.1"
                     /translation="MTRDEYLAELDKYLRKLPKADYYEAAENSSQLELNDGSIKDSSI
                     TVADTKEENDYDYTDPSELAINHVTIKEKNTINGGDININTTLANPRDIAYHVTTRGN
                     IKLSSRFSNAKLNTDAATGATSFHSDIANTVNQSDLSIH"
     gene            1093..2148
                     /locus_tag="TU818_001126"
     CDS             1093..2148
                     /locus_tag="TU818_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL0923948.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEVDNKTKSEASSQKLEPIVDIRYSLL
                     NHDLTIETADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGESDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCNIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(2252..4534)
                     /locus_tag="TU818_001127"
     CDS             complement(2252..4534)
                     /locus_tag="TU818_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL0923949.1"
                     /translation="MLEGLKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKT
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTAGLGQLAADMPAYLDGVSRLSKGANQLNAGLTQLALGSD
                     LSQDKQANIQALMASLPKLNQAIQQLKTNLSLSLAPNVDSGAIAKHLADMTRLVQELV
                     VDDTADKNNQLAALQATATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSE
                     ELEAMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQL
                     LSGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAF
                     GANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSE
                     KDKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGM
                     ISTVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVSWDARYGAFASLI
                     MLLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGF
                     LLSFMAIGVLIYRPKDKQSS"
     gene            4666..5199
                     /locus_tag="TU818_001128"
     CDS             4666..5199
                     /locus_tag="TU818_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL0923950.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
     gene            complement(5406..6017)
                     /gene="rpsD"
                     /locus_tag="TU818_001129"
     CDS             complement(5406..6017)
                     /gene="rpsD"
                     /locus_tag="TU818_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL0923951.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(6541..6813)
                     /locus_tag="TU818_001130"
     CDS             complement(6541..6813)
                     /locus_tag="TU818_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL0923952.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            complement(6830..8206)
                     /gene="dnaB"
                     /locus_tag="TU818_001131"
     CDS             complement(6830..8206)
                     /gene="dnaB"
                     /locus_tag="TU818_001131"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL0923953.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKESDSTEEALEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            complement(8227..8679)
                     /gene="rplI"
                     /locus_tag="TU818_001132"
     CDS             complement(8227..8679)
                     /gene="rplI"
                     /locus_tag="TU818_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL0923954.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLNIAEA"
     gene            complement(8676..10652)
                     /locus_tag="TU818_001133"
     CDS             complement(8676..10652)
                     /locus_tag="TU818_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL0923955.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAEFMESKQVFY
                     RRVNMDRFYFFTDYKILKGLMDDKFSILEQFRKEAQEAQLPLTLSMGISFGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISISQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISATDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTILSMAHIEASFVIVETGADKIAISARSRSKINVQRMMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            complement(10740..12638)
                     /gene="mnmG"
                     /locus_tag="TU818_001134"
     CDS             complement(10740..12638)
                     /gene="mnmG"
                     /locus_tag="TU818_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL0923956.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGRVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQISHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKSLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEGLDAKLIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            complement(12641..13105)
                     /locus_tag="TU818_001135"
     CDS             complement(12641..13105)
                     /locus_tag="TU818_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL0923957.1"
                     /translation="MVQDFRTRIADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAVKREVLEEVGAEVSVAQLAFVVENQFCLEGVNFHQIEFHYIVSLLSDS
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            complement(13310..14434)
                     /gene="mnmA"
                     /locus_tag="TU818_001136"
     CDS             complement(13310..14434)
                     /gene="mnmA"
                     /locus_tag="TU818_001136"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL0923958.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGVVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFISEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            14715..15386
                     /gene="sdaAB"
                     /locus_tag="TU818_001137"
     CDS             14715..15386
                     /gene="sdaAB"
                     /locus_tag="TU818_001137"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL0923959.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQVAVKQIATIPNLHN
                     VNFFD"
     gene            15398..16270
                     /gene="sdaAA"
                     /locus_tag="TU818_001138"
     CDS             15398..16270
                     /gene="sdaAA"
                     /locus_tag="TU818_001138"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL0923960.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALANIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            16304..16939
                     /locus_tag="TU818_001139"
     CDS             16304..16939
                     /locus_tag="TU818_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL0923961.1"
                     /translation="MKAILFDLDGTLVDSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEATFSAFFRNQHDVEVAITHFRDFYRELGIYQARLYSGITELLDNLSQEGLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSISNRCHKLDIVKACLQDFAINKKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(17000..17611)
                     /locus_tag="TU818_001140"
     CDS             complement(17000..17611)
                     /locus_tag="TU818_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL0923962.1"
                     /translation="MFKQDILKQRYFSFGIVAAAIALLAVVFAFSSENVNTDSYAKAS
                     DTKVVKKHHKTKKSTVAKAATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(17867..18676)
                     /locus_tag="TU818_001141"
     CDS             complement(17867..18676)
                     /locus_tag="TU818_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL0923963.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFTLLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDTLAIILVVILGIFLFCLKSPSRLT"
     gene            complement(18669..19511)
                     /locus_tag="TU818_001142"
     CDS             complement(18669..19511)
                     /locus_tag="TU818_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL0923964.1"
                     /translation="MSIHFQNVSYTYQAGTPFEGRALFDVNLDIVDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTTGKVTVAGKEITSQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEELFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVANYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQRLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(19487..20326)
                     /locus_tag="TU818_001143"
     CDS             complement(19487..20326)
                     /locus_tag="TU818_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL0923965.1"
                     /translation="MSNIIEVKNLTFKYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEDNVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIERVHQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKKDGYPIQGIYLTEKELEEQLCQFI
                     SKM"
     gene            complement(20329..20871)
                     /gene="pgsA"
                     /locus_tag="TU818_001144"
     CDS             complement(20329..20871)
                     /gene="pgsA"
                     /locus_tag="TU818_001144"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL0923966.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARKWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGDKVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(20884..21888)
                     /locus_tag="TU818_001145"
     CDS             complement(20884..21888)
                     /locus_tag="TU818_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0923967.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(21938..23221)
                     /locus_tag="TU818_001146"
     CDS             complement(21938..23221)
                     /locus_tag="TU818_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL0923968.1"
                     /translation="MTSLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     RFGSLDTSFTVNCQRFDLPSGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYYPVIKSRSIDMDVATAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAVLLGWTSKTYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDVNEEHLELVKKEMYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(23223..24467)
                     /locus_tag="TU818_001147"
     CDS             complement(23223..24467)
                     /locus_tag="TU818_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL0923969.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSALKAKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRSYIDPSYTLSSWLDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            24682..25095
                     /gene="yaaA"
                     /locus_tag="TU818_001148"
     CDS             24682..25095
                     /gene="yaaA"
                     /locus_tag="TU818_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL0923970.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            25097..26206
                     /gene="recF"
                     /locus_tag="TU818_001149"
     CDS             25097..26206
                     /gene="recF"
                     /locus_tag="TU818_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL0923971.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPNLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDNDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMNQLKTTHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNTRQTKLLGAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIERDSIMID"
     gene            complement(26271..27134)
                     /locus_tag="TU818_001150"
     CDS             complement(26271..27134)
                     /locus_tag="TU818_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL0923972.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTIGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGIIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(27305..29734)
                     /locus_tag="TU818_001151"
     CDS             complement(27305..29734)
                     /locus_tag="TU818_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL0923973.1"
                     /translation="MMILTDEQRQRIAEEEYEKHTVGSPVLIDDDNSEFSIGYVSQIE
                     DSISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGN
                     DLPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVT
                     SVSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKLLHDRIYNYVDPHDIIGMGFDQKE
                     GAVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPIDIDSDNRL
                     DTKVEELYLGFRNYFDSSTSARYGVLSDKQTIVINAGVLTNLAQNLQSSISGDLQTIR
                     HITEKCQAKNDAIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLF
                     DMLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWID
                     SIIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKVDGISDSLKEVFSVELQDI
                     IELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTG
                     LLDDVRDILQAFDEQVEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNIFKNIVTV
                     LERRFSDRVYVERTEIKDETSTTTRSYWGNLGALYPCRIRSGIASARAEVCPLVPALT
                     DTIQRVNTARHRLQNLHGDLSRLIEKGVYSALDLDDIITSQKMVGRLLDKIIVELSFV
                     KATIEASMSGQAASAMVNHLALLLKRLGYFSQLVADCFGTQVTKVPNKAPARASHKVK
                     RFSLNNPLALQ"
     gene            complement(29737..>29896)
                     /locus_tag="TU818_001152"
     CDS             complement(29737..>29896)
                     /locus_tag="TU818_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0923974.1"
                     /translation="INPMGGFSIHLIINDDPDTYLRVRLSRYDLERNLEIASNYRSEK
                     LEKLLKGE"
BASE COUNT         9189 a         6531 c         5479 g         8697 t
ORIGIN      
        1 tgagagatat gttggcttct gatttcatat aagacctgcc atcgcccttc ctgccaaatc
       61 aaaggtaagc aaaccgcata acatcgctcc tcacccaagg gcctagcctg ataatgttca
      121 ataatgctct tcatctgtcc ttctccttat catatccatc actaagctac tttcatagta
      181 taaaatagta atcctttggt caagaaatgg ctccgattac tctctatgat atataaaatt
      241 tttatatata aaatattgac atattaaaac agaaactcta tacttaatat ataaaataat
      301 tatatataaa tacgaggcag gaagggagta accagatgta ttttccagta tctgctacct
      361 tgattgaatt tttgatttta tctattgtcg acaagcatga ttcctatggt tatgatatca
      421 gccaaaccat taagcttgtc gctaatatca gggaatcaac cctataccct attttaaaaa
      481 agctagagaa atcagactat ttaactacct atagtcagga acatcaaggt cgcaagcgta
      541 actattacac cattacagcc aaaggcgaaa agcagctgat tttcttaaag gaagaatggc
      601 aaagctacaa ggccacccta gatggcatta ttgaagggag attaaggcat gacaagagat
      661 gaatacctag cagagctaga caaataccta cgaaaattac ctaaagcaga ttattatgaa
      721 gctgctgaga actcaagtca gctagaactt aacgacggca gtatcaaaga ctcttctatc
      781 actgtagctg atacaaaaga agaaaacgac tatgactata cagacccctc cgagcttgct
      841 ataaatcatg tcacaatcaa ggagaaaaac acaattaatg gcggcgatat taatatcaat
      901 accacattag caaatccaag agatattgct tatcatgtca caacaagagg caacatcaag
      961 ctcagctctc gtttttcaaa cgccaagctt aacacagacg cagcaacagg agctacttca
     1021 tttcactctg acatagccaa tactgtcaat caaagcgacc tatcaattca ttaatcaagg
     1081 gaggatatca taatgactaa acaagatttt ctagacaagc taaagcagca gatcaaccat
     1141 ttacctcaaa aggattacca agaaatcatt gaccatttta cagagtattt tgacgaggct
     1201 ggtcctgacc atgaacaagc tattcttaaa gaactgggaa atccagagga cattgccaag
     1261 gagctattaa aagccttaga tctccccgaa aaaacagacg aagatgactg gacgaattgg
     1321 gaagttgaca acaaaacaaa gtcagaagca agctcacaaa agcttgagcc aatagttgac
     1381 attcgctata gtctgcttaa ccatgattta accattgaaa ctgctgacat tccttaccct
     1441 actatttcat acgatgataa tcgcatcaca ataagccaag atagtgacgg catgctcaat
     1501 atcattgaag actcagcagt acaaacaata cagtatggct ttcatttcct agaccgctgg
     1561 cttgcaaaat atcaacccat taccttgaca ctacctgtca accaccacct gaaaaaaatc
     1621 tctggagaaa gtgacaacaa cgatgtcacc ataaggcata tacattgtga tagcattgtc
     1681 tctaacactt acaatggaac gatttctatc agtcatttat cagatagcac tgtcaaccta
     1741 agcagcaaaa atgggaacat tattttagag cattgcaata tccagtctag taaatgtcaa
     1801 gccaaaaatg ctaacctcag ctgtgacaat agcaccctaa taaattgcca gctgaacaat
     1861 aacaatggaa acatcagatt agaagcaagt cagctaacag aaaccttcat tgaaaacaaa
     1921 aacggtaata tcatagggca gcagctgtcc ttttccaatg acatcactat catcaataag
     1981 aatggaatca ttgacatcaa ttgtcctaga gaaaacctca tctactatga cgtaaaggct
     2041 tcaaataata atggatttgt aacgattagt caagaagcag gtcgtcaaac accctttaaa
     2101 gcacagctta ccatttccaa taataatggt cttatctccg taagctaaac caaccataaa
     2161 aaaagcttct agaaagagct taaaccacaa tttctagaag cttttttatt atatctactg
     2221 tttaacgata acctgttatc tcagctatta tctaggacga ttgcttgtcc tttggacgat
     2281 aaatcagcac tcctatagcc ataaagctta acaaaaagcc aactaataca ctcgtctcta
     2341 aacctatctg ggcagttaat gatattgtct gacgaaggcc agagacaata taagacattg
     2401 gaagataagg atggagaatc tggaagatct gaccactcaa ctcaatagga taagaaccac
     2461 ccgcagcacc aacctgtagc aacagcataa ttaacgaagc aaaggcacca tatcgagcat
     2521 cccagctgac caatgcagtc actaaagcca tcaaggccca tccactcagc ataataaagc
     2581 ctaaggtctt gataccgtca ttagcttcaa agcccagcag ttgaagtgca gcgtaaagaa
     2641 taacagagcc aacggtcgaa atcatgccat tgatcagtaa tttttgcttt gcccaatccc
     2701 atctatcttt aatcggctta ccagataagg cctctgcaaa aataatattt gtagacaagg
     2761 caactaccat tagagacaca gcaatcatat aaggagccat gccaatacca ttggtcctaa
     2821 ccttatcctt gtccttctct gataacgcta ctggatcaga taccatatca gcattctggt
     2881 cctctaccca agccattgaa agctggtcag aagcttttga tagtgaggtc gttaagcttg
     2941 acagacctgt tgacagagtt gtcaagccat ctgtcaactg agagctgcca gaggagagct
     3001 gattggctcc aaaagctagc tgattagcgc ctactgtaag ctgctgtcca cctgctaata
     3061 attgactgga ttgatggtta agagctgttg cccctgtagc aagagtagac aggcctgctg
     3121 taagagcttc attcttagct gtcaattgat taaagccgcc agcaagagct tgactacctg
     3181 ataagagctg ggctgttgtc gctgagtgaa cagcccttaa accagttgaa agctctgaca
     3241 atgccttgcc tgtgctaggt aggatttgat cagcttgata agccagctga ttaacaagtg
     3301 ctttaaagtc cctcagttga tcagctacac cagcacttgt tgacatagcc tctagctcct
     3361 cagacatggc ttgcagtgat gtcaacatag cctttgctga tattgttact ttagttgaag
     3421 tattggaaat agctgagctc agctcctcct gctgctcaga gttgagacct tgataggtag
     3481 ctgtagcttg tagagcggct agctgattgt tcttgtcagc agtatcatct accacaagct
     3541 cctgcactaa acgcgtcata tcggctaaat gcttagcaat ggctcctgag tccacatttg
     3601 gtgccaaaga caaggaaaga ttggtcttta gctgctggat agcctgatta agctttggta
     3661 ggctagccat taaagcttga atattagctt gtttgtcttg agacagatca cttcctagag
     3721 ccaattgggt caagccagca tttaactgat tagcaccctt ggataaccga gaaacaccat
     3781 ctagatacgc tggcatatca gctgctagct gtcctaagcc cgcggtatca agctgaccaa
     3841 caccggctgt ataggcagct ataccactag atagattacc cgctccttga gacaagcgag
     3901 cacttgattc agacaaggtg ttcaaatgcc ttgacattag ctgactgctt gccctagcaa
     3961 ttactaagcc agcggctaat tgctgaccgc catttgaagc ttcctttaga ccagattgga
     4021 gctgatgcat gctcttaaaa acggaggtga tataggtctt ccttatattt ttagaaacag
     4081 cctctctcaa gtgattcata gcagattcac ccattttaga agcgataaag ctatggccct
     4141 tactagtttg atagctaaca atcagcttct ctggctgctg atctaatagc gtagtggcct
     4201 tttgtgacaa atcctttggc aacgtaatcg tcatataata acgacccttt tccaagccct
     4261 tttgtgcggt atctgcagcc acaaaatgat aatccaattc cttattttta gacatattgt
     4321 ctaccatatc gttaccaata gtcagtctct tgttattcaa gtaagcaggc ttatcctgat
     4381 tcacaactgc tacaggcaac tgatcaaccc gaccataagg atcccacatg gaccctaaaa
     4441 aggacaaatt atagagagct ggtactagag caaccccaat cattgtcact actagcttac
     4501 gatttttgat tattgctttt aatccttcta gcattatttt ttctccaaat agacatactg
     4561 ttcaaaaatt atgataaaat atattataca aataaagtga cattttacaa ggaaaaaata
     4621 aattttttag acataatgtc tacaagtgtt caaaaggaga taatgatgga tagccgcaag
     4681 cagcaaacca agaaggccat tcttaatgca atggtgagct tactaaaaac cgaaagcttc
     4741 gatgatgtaa caaccgttca gcttgctaaa atggcaggca ttagtcgttc tagcttttat
     4801 actcactata aagacaaata tgagatgatt gattactatc aacaaacctt ttttcacaaa
     4861 ttagaataca tttttgaaaa agaataccaa aacaaggagc atgctttttt agaagtattt
     4921 gaatttctca agcgagagca actactatct gctctgctat cctccaatgg tacccgagaa
     4981 atccaaagct ttatcattaa caaggttcgt ctgttgatca ctaccgatct tcaggacaag
     5041 ttcagtaagg acatcttgtc cccaaccgaa aaggaatatc gaagcatcta cctagcacat
     5101 gcctttttcg gtgtctgcca aagctggatt gctaaaggaa aaaaagaatc ccctcaggaa
     5161 atgactcgtt tcgtcttaaa aatgctatct aaaacatagt cctgcactaa tgatgtcaaa
     5221 tccagtacca aaaaacaact ttgtaaacta tttcttactg agtttataat gatctttatg
     5281 cctaacaata ccgacctcca atcgttagac ttttggtcta acctttgggg tcggtacata
     5341 aatcagctaa ccgctcaacc aaaaaagccc actgttgtgg gcttcttata atataaagtc
     5401 ttatcttaaa gcattttgtt gtagaattca acgacaagtg cttcattgat ttctgggtta
     5461 atttcgtcgc gctctgggag gcgagttaat gatccttcaa gcttttcagc gtcaaatgaa
     5521 acaaaagctg gacgtccaag agttgcttca actgcctcaa ggattgcagg aaccttcatt
     5581 gatttttcac gaacagagat gacttggcca atctcaacgc ggaatgatgg gatatcaaca
     5641 cgcttaccat caacaagaat atgaccatgg ttaacaaact gacgtgcttg acgacgagta
     5701 gttgcaagac ctaagcggta aaccacattg tcaagacgac gctctaaaag aagcatgaag
     5761 ttgaaaccaa gagttccttc tttgattttt gtagcttgta cgaataggtt acggaattgt
     5821 ttttccccca taccatatga aaagcgaagc ttttgcttct cagcaagttg caagccatat
     5881 tctgaaagct tgctacggtt gttagggcca tgctgaccag gtacgtagtt acgacgtgcc
     5941 aattccttac ctgtgcctgt caatgacaag ccaagacgac gtgattgttt ccatgatgga
     6001 ccagtataac gtgacatgta tcatgtcctc ctctaaaaaa tataacgagg aaataactgt
     6061 ttgaaaaatc ctgattcgtg caggaggttt tcgcctaaac agcaaaggtt actcaattta
     6121 gttaaccgcc tgttgacgag cttcatattt ttctgctgtt atttcacaca aaactaattg
     6181 taacatgaaa aaggtattga ttcaagtttt ttttacattt ttaatatcat atcatcaaaa
     6241 atggttagct gtaagctcaa agatgatgtt aatcatatgg caaacaagct tttacacaac
     6301 acttcccgag taaacaaggc tttttaatac cgataggaaa ttctttgaaa atagcatatt
     6361 atgttttgat atctaatacc gagagtctca gagtaactgc ttttcaagaa agctagtccc
     6421 tattattagt ccgggcttca ttcatttgct aataagttct tcaaggcttc aaattgattc
     6481 atatctttac acagctgtca acaaagtgta aagaaaaagc cctaaatggg cattgatttt
     6541 tcaatcaaaa taacgaatca gtgttttttc cgtcaaaata tctgaatagg tataagactc
     6601 aacataagaa ttattcgctt cccctgaagc atctgggttc ccctgatact caatgataaa
     6661 taaagaaggg taaacctcta tcaatctgcc aaccttattt ttttcacgct tacgaccatt
     6721 ttcaagtgtt aactcaacca actgaccttc atgagcctta atgtcttcct ttattttttt
     6781 cattttggca acatctgtaa atgcatcact cattctcttt ccctctttct tatctttcct
     6841 caaattgagc tattgtcgaa aatttattgt attccttttg aaacatcagc ttaactgtcc
     6901 cacgcgcacc tgccctattt ttctcaagaa tcacctcaat tgtattatcc tcaagagcct
     6961 cttctgtgct gtcgctttct ttacgataat aatcatctcg gtacaaaaat gcaacaatat
     7021 ccgcatcctg ctcgatagag ccagactcac gaatatcaga caaaactgga cgcttgtcct
     7081 gcctctgctc aacaccacga gaaagctgac tcaaagcaat aacaggcact tttaattcct
     7141 tagctaaaat ctttagctgc cttgaaatat cagaaacctc ttgctgacga ttttcaggtc
     7201 ttgtaccagt gatcagttgg aggtaatcaa tgacaattag ccctaagcct ccctcaacct
     7261 cctgagacaa tttacgtgcc cttgctctga tctcagtaat cttaatgcca ggtgtatcat
     7321 caatatagat aggtgcttct gccaaggctc cttgggcaat ggtcacatta ttccagtcct
     7381 gatcagtcaa ctgaccagtc ctcaagctat gtgaattgac cattccctca gcggccagca
     7441 tacgatcaac aaggctttca gctcccattt ctaaggagaa aatggcaact gctctctttt
     7501 gctttgtacc aacattttga gcaatgttta agacaaaggc tgtcttaccg actgcaggac
     7561 gagctgctaa aataatcagt tgatctgggt gtaaacctgt tgtaatcttg tcaagatccc
     7621 taaagcccgt tggtaaacct gtaacgtctg atgtctgctt agaacgaacc tcaagatttt
     7681 cataattaat ctttaaaacg tctgagatct tacgaaagcc actgcgattg ctatgctcac
     7741 tgatatcaac caaggccttc tcagcacttg caataatatc ctccgagtca gatgctcctt
     7801 cataggctaa gtttacagtc tctgtcaacc tattgatgat atcgcgtagc atagcctttt
     7861 cagctactat tttagcatag tattctgcat tggcactggt aggtacacta ttaaccagct
     7921 caacaatata agacaagcca ccaatatgtt gaaggtcccc ttgatcatca agaatcgtcc
     7981 ttaccgttgt tgcatcaata gcatcatttc gatcactaag ccttatcatt gccctgaaaa
     8041 tgaccttatg agaatactta taaaaatcct ctggaccgat aaattctcta acggtaatca
     8101 acttgtctgg ggaaataaag atagagccta gtacagactg ctctgccaat aaatcttggg
     8161 gttgaactcg taactcagca acttcaggca aactcagcac ctccaaatct tttttaggct
     8221 gatgtgctat gcctcagcaa tgtttagttt tatttcagct gtcacttctt tatgcagctt
     8281 aactggcact tcgataagac caatagcacg aatagggtga tctaaaacaa tatgacgctt
     8341 gtcaaccttg accttaaatt gcttttgcaa ttcctcggaa attttcttag ctgtaattga
     8401 gccaaaggta cgcccatctg gtccaacctt ttccttaaac tggacacgag ttttttcgtc
     8461 atctaagatt ttcttaacag ccttagcctc tgctaggatt tcagcctggg ctttttcctc
     8521 agctttttgc tgccctctta gctggccaat tgcttgactg ctagcttcct ttgctaaatt
     8581 tttcttaatc agaaaattct gagcataacc agtgggaacc tccttgattt ctcctttttt
     8641 tccttttcct ttaacgtcaa ctaaaaaaat gactttcatg actctacctc tcttgtttct
     8701 ttcattgtgt tatcaattgt ttctagtaac agctgcttag cctcgctaag actgatatgc
     8761 ttcatctgac acgctgctaa gttgaaatgt cctccgccgc caagcttttc catcattctt
     8821 tggacattga tcttactacg acttcttgct gatatagcaa tcttatcagc tcctgtctct
     8881 acaataacaa agctagcctc aatatgggcc attgatagta tggtatctgc tgccttacta
     8941 gcaatgacat tactataata ttgcccagca agcccagttg caacgataat ggagtcgcta
     9001 aggcgctcac ctctgagaat gatctcatta acctgcttat agtcatcaaa atcagttgct
     9061 gaaatatttt gaatttcgac gctatcacta cctctgcttc gtaaataact ggcaacatca
     9121 aaggttctac tggtgacacg tgttgaaaaa ttcttagtat ccagcataat accagccatc
     9181 aaaacacttg cttgaatctt gtttaagcgc ttcttcgcat tttgaaactg gattaattct
     9241 gtcactagct ctgcggcact gcttgcacca ctttcaataa aggtcaagat agcattatct
     9301 ggaaaatcat catctcttcg gtgatgatca acgacaataa catcttgaaa ttgctcgtaa
     9361 aattccttag acaaggttaa ggaaatctta gagtggtcca ccattactaa cagtgatcta
     9421 ggggtcgtaa gccccattgc ttgagaaata ctgataagac gtgtcttacc atcagcctgt
     9481 aagcgctcaa tagctctttc aatgtctgga ctcatctcat ccggattata gacagcaaag
     9541 ctgttttcaa taatgttact agcaaaaaat tgcatgccaa cagccgagcc taaggcgtcc
     9601 atgtccagtt tacggtgacc tacgataaac acattatcaa ccattttgat acggtctgaa
     9661 atagctgtca tcatggcacg cgtcctagtt ctagagcgtt taaccgtaga aacagagccg
     9721 ccaccaaaat agaccggatt tgtatggtct gcattttcac gaataacaat ctgatctccg
     9781 cctcggacaa gagcaatatt cagattctca agagcaacct gaccaatttg acaatgattt
     9841 tcctctccaa aggaaatgcc catacttagg gtcaatggta gctgcgcttc ttgggcttcc
     9901 tttcggaact gctctaaaat agaaaactta tcgtccatca gcccttttaa gatcttatag
     9961 tctgtaaaaa agtaaaaacg atccatatta acacgtcgat aaaatacctg cttagactcc
    10021 ataaactcag ctatgaaatt agccacaaat gaatttatct ttgacgtatc agcatcagat
    10081 aagtcatctg taatgtcgtc ataattatcc acagaaataa taccaataac tggctttagc
    10141 aagctagaat ctgctgattg tctactacca acagagctat caaaaaagta aaaaatacct
    10201 gatgccacat caatataaga cgtgtatcga ttgccagaaa cctcaaaggt ttgagaaata
    10261 tcacttttac gcttatcagt gagaagctgt tggatcatct gttcctgtaa aaaaccggcc
    10321 tcatcagtga aaatcagctc tgcgtaagga ttgtaccatt caatagcatt ggtttcttga
    10381 tcaaactgaa taacaccaac tggcatgtta tccagtaatg tttttaaatt attttctgtt
    10441 tgttcgttca atagctcaat gtggtctaaa tcagacaatt cgtaaacctt tttttgatac
    10501 caaagcaagg ccgcaacaaa caacaacact aaaaaaatag ctagtgtaat cagcattttt
    10561 gattgcatga ttctaacaca taaggctagt aagccgaata aaatcaactc catcataatt
    10621 aaatgaatgg tttcaaaacg aaatcttttc atctttaacc tcttaatccc gtattatacc
    10681 ataaaacagc cctgaaatac agagctgtca gtggttttga gattacaatt tgatgactat
    10741 tatgttttac ggcgagcctt tccattacct tcaaggtaaa ccattaaaat gctaatatct
    10801 gccggattta cacctgaaat gcgactagcc tgaccaatgg tttctggatt gattttctta
    10861 aatttttgcc ttgcctcagt agcaattgag tcaatagcgt cccaatcaat ggtcttagga
    10921 atccgctttt cctccatacg cttcatttta gcaacctgat caagggcctt tttgatatag
    10981 ccttcgtatt tgatctcagt ttctagtagc tcaatcagct tagcatctaa tccctcagca
    11041 gcaggaccta taaatgacac tacagtggca tagtcaacct ctggtcgacg cataaattcc
    11101 ttagctgtca ttgcgtccgt caaggactta aagccaagct tttgaacacg agcattggtt
    11161 tctttgattg gctttaattt gatactatct agcctcttta attcattgtc aaattgattt
    11221 ttcttgattt caaaggcaga ccaacgctca tcgtcaacca agccaatctg acgaccaatt
    11281 tcagtcaatc gcatgtccgc attatcatga cgaaggataa gacgatattc tgcgcgtgat
    11341 gtcagcaaac ggtaaggctc caaggttcct ttggttacca aatcatcaat cattacacca
    11401 atataagcgt cgctgcgctt taaaatgagc tcaggcttac cctgaacctt caaagcagca
    11461 ttgataccag cgacaaggcc ttgaccagca gcttcctcat agcctgaggt tccattggtt
    11521 tgcccagctg taaaaagccc tgaaatcatc tttgtttcaa gggtagcacg aagctgatga
    11581 ggtaatacaa tgtcatactc aatagcatag cctgttctca tcatctcagc attttcaagc
    11641 cccttaatag agtgaaccaa ttccttttgg acgtcctcag gaagacttgt ggatagacct
    11701 tgaacataga cctcctcagt gtcaaagcct tctggttcta aaaagagctg atgacgctct
    11761 ttatcagcaa atcgtacaat cttatcctca attgatggac aatagcgtgg gcccactccc
    11821 ttgacgactc ctgaaaacat aggtgctcga tataggtttt tagtgatgat atcatgacta
    11881 atctgattag tgtaggtcag ccagcaagga atctgattag ccaaataatc tttgtcctta
    11941 gacataaagg aaaaatgatt tggagtcaca tcaccaggct gaatctctgt cacctcataa
    12001 tcaatagaag aagccttgac acgtggtggg gttcctgtct taaagcggcc aatttcaaga
    12061 ccaagctttt tcaaattatc agctagtgtc actgaggcca agctgttatt cgggccagac
    12121 gaatatttca attctccaag gataatctca ccacgaagag ctgtacctgt tgttatgatc
    12181 actgcctgag ctgcatattt ttgccctgtt gctgtcagca ctccaacaac cctaccattt
    12241 tctactaaaa tatcatcaat catagactgg cgaagagtga ggttttcttg cttttcaaca
    12301 gtatgcttca tctcacgtgc atacaagctt ttatctgctt gagctcgtaa tgctcgaact
    12361 gccggtccct tacctgtatt gagcattttc atttggatat aggttttgtc aatgtttttc
    12421 cccatctctc caccaagagc atcaatttcg cgaacaacaa tacccttagc tgaccctcca
    12481 atagagggat tgcatggcat aaaagccagc atatcaagat ttatcgttgc taataaggtt
    12541 ttacacccca tacggctagc cgctaagctg gcttcaacac ctgcatgtcc tgctcctaca
    12601 acgatgacat cgtaggattc tgtaaattca tgtaccatat ctactccttt atctcaatat
    12661 gttttatatg ctgaggctgc ctgtcccaat gctttatagc cctttttaaa caactaggat
    12721 tgagccttat cttatctaga tcatcaagag caacccactc acaaacccta gtacaatcac
    12781 cctcaactac agaagggcta gaatcagata atagactcac aatataatga aactcaatct
    12841 gatgaaagtt cactccttct agacaaaatt gattttcaac cacaaaggct aactgagcaa
    12901 ctgaaacctc agctcctacc tcctctagaa cctcacgctt gacagcttct tctgtgcttt
    12961 ctccaacatg aatagcacca cctaaaagat aatagtcctc tttgggtgat ttggcaagat
    13021 aaatatagcc atccttaatt attaacgctg aagccctaac accaaagcta tggtctgcta
    13081 tccttgttct aaaatcctga accatctttt ctccttgaca ctgtttttaa gctataaaaa
    13141 tagtcaaaac ctgagaaagc tgtaagccaa aaagacttac aattcccatg agctttgacc
    13201 atcatcgtta ttgttaacct tattctatca aaatctgcca gcttgtcaag acttatcaga
    13261 tgacaaaacc gtcaacttta ttgacacatc tgtcaattaa catgtcaagc taaatatatt
    13321 gacaaggctc gccatcttta tacgccatat caataatacc accaccaaga cactcatgac
    13381 catcataaaa aacgactgct tgaccaggtg taatcgcacg ctgaggctca gcaaaaacaa
    13441 ccttagcttt gtctttcttg acatgaaccg tcaccttaga atctggctga cgatagcgga
    13501 actttgctgt gcattctaag gtgaattctt caggaacttc tcttgtaaac tgaatgacag
    13561 aagcgtcaag actagttgac attaaggact cgtggtaaaa gccttgacca acataaagga
    13621 tattttgtga aaggtctttt ccaacaacaa accaaggctt gttatctcca ccctgctgac
    13681 caccaatgcc aagtccccca cgttggccaa tagtataata catcaagcct gcatgctctc
    13741 ccatatcacg accatcaaca gtcatcatac gccccttttg agctggtaaa taatggctaa
    13801 gaaaggtctt aaaattcttc tcactaataa aacaaatccc tgttgagtct tttttctttg
    13861 ctgttgcaag gcctgcttgt tcagcaatag cacgtacctc tgatttttgc aggtgcccca
    13921 agggaaacat ggttttttgg agttgctctt gtgatagttg gcttaaaaaa taggtttgat
    13981 ccttaccctt atcaagacca cgcagcatat ggactacacc attctcatca cgtttgattt
    14041 gggcatagtg acctgttgcc acataatcag cacccaatgt catcgcataa tcaagaaagg
    14101 ctttaaactt tatctcctta ttgcacatga catcaggatt tggggtgcgt cctgaacggt
    14161 attctgctag gaaatactca aacactctat cccaatactc tttttcaaaa ttaacagaat
    14221 agtaaggaat accaatctga tcggctacgg ctgccacatc tttataatcc tcagtcgccg
    14281 tacaaacacc aaattcatct gtatcgtccc aattcttcat aaagacgcca atcacatcat
    14341 atccctgctc ctttaacagc aaggcagtta cagatgaatc aacaccgcca ctcatgccaa
    14401 caacaacacg tgttttcgag ttatctgtca tcatttattc tcccatcaat ataagataca
    14461 aggacatgag aaaaagaata gaacgaatca acttgcctaa acaagactct agcaaatggt
    14521 tcatttctat attttttgtc tttgtccaag tgttttctca aagctcgatt tgaaggtcga
    14581 tttgaagcgc cgctagacgc atgactatta taacagtatt gtctcttatt tccaacaata
    14641 tcttttttca taacaaacga catttgatta gcgatttgtt ataataaaaa ggataaaaag
    14701 agcatggagc atatatgaac acacaaaaat ttcaatcagt ttttgacatc attggaccag
    14761 tgatgattgg accatcgagc agtcataccg ctggtgctgt tagaatcgga aaggttgtcc
    14821 actccatttt tggagaaatt cctgatgagg tgacctttca tctatacaat tcatttgcta
    14881 agacctatca aggccatggt accgacaagg cactagtagc tggtattatg ggcatggata
    14941 cggataatcc aaacatcaag aattctcttg aaattgctca tcaaaagggc attaaaattt
    15001 attgggatat tttaaaggat agcaatgctc cccaccccaa tactgtaaag attagtgtca
    15061 aaaaggctga taaagcaatg agcattacag gtgtgtcaat tggaggagga aacattcagg
    15121 tcacagagct aaatggtttt tctgtttcct tgtctatgaa tactccaacc ttgattattg
    15181 tccatcaaga tatccccgga atgattgcta aggttacaga tatattgtca gctagtgata
    15241 ttaatatcgc tcaaatgact gtgactcgtg aaagtgcagg tgagaaagcc attatgatta
    15301 ttgaggttga ttctcgtgat tgtcaagttg ctgtcaagca gattgcaact attcctaatc
    15361 tgcataatgt caatttcttt gactagaaag gtatattatg ttttacacaa ttgaagagct
    15421 tgtcaagcag gctgatgata ggtttgatgg taatgtagca gagctgatga ttgctacaga
    15481 ggttgaaatg actggtcgaa gcagggcaga aatcctatcc atcatgtcac agcatttaca
    15541 ggtaatgaag gattctgttg tcagcggatt gacagcaacc aaatctatta gcggattgac
    15601 tggcggtgat gctcttaaga tggatcatta catcaaaaaa ggaaaggggc tttcagatca
    15661 aaccatttta acagctgtga gaaatgctat ggctgtcaat gagctaaatg caaaaatggg
    15721 acttgtttgt gcaaccccga ctgctggaag tgcaggctgt ctacctgctg tccttgctgt
    15781 tgctattgat aagctcaagc tatcagaaaa ggaacagctg gactttctct ttacagcagg
    15841 tgcctttggc ttagtcattg gaaataatgc ctctatctcc ggagcagaag gaggctgtca
    15901 agccgaggtg ggctctgcct ctgcaatgag tgctgcagcc cttgttaagg cagcaggtgg
    15961 taccgcttat caggctagcc aagcggtagc ctttgtgatc aaaaatctat tgggattggt
    16021 ttgtgatcct gttgctggct tagtcgaagt tccctgtgtt aagcgtaatg cattaggatc
    16081 aagctttgct cttgttgctg ctgatatggc attagcgaat attcagtcac aaattcctgt
    16141 agatgaggtt gttgatgcta tgtatcaggt tggtgccgca atgccaacag cctttaagga
    16201 gacagctgag ggaggattag cagcaacccc aacaggtaga cggtatagta aagaaatttt
    16261 cggagactaa tataatcaag taacgataga ctgaggagac gtcatgaaag caatcctatt
    16321 tgacttagat ggtactttgg tggattctag tataggaata ctaaatgcct ttgaatacac
    16381 ctttcaaaaa atgaaaatcc cttgtcctga tcatagcata ttatcgtctt acatcggacc
    16441 acccttagaa gcgacctttt cagcattttt taggaatcag catgatgtcg aggttgctat
    16501 aacacacttt agagattttt acagggaatt aggcatttac caagcaaggc tttattctgg
    16561 aatcacagag ctattagata atctctcgca agaaggtctt gacctctatg tgacaactag
    16621 taaatatgaa cctatggcaa ggcaaatgct tcaggattta acgattagcc attatttcaa
    16681 agctatccta ggctctattt ctaatcggtg tcacaagttg gatatcgtca aggcatgctt
    16741 acaagatttt gctattaata aaaaagaagc tataattgtt ggagatacca aatttgacat
    16801 gattggtggt aaacaagcag gcattacaag acttggagtt acttggggat ttggttgtca
    16861 agaggattta caagcacatg gcgcacaata cattggacac acaccccaag aggtgattga
    16921 gattatccag tcattgtaaa acgatactaa aaacctatca tcacacaaga tgataggttt
    16981 ttaacgctgt tatctgttct tagtagcccc aagctgataa gccctgtgca cgataggcat
    17041 ttaaggctga atttacctga tcctgaacgg ttgcagttga tccccagcct ggcatggttt
    17101 ggaataatcc tgaagcacct gaaggattag ctgcgttagg gtttccattt gactcacgag
    17161 cgataatggc ttcccaagta gcttgtggaa caccagtagc tgccgccatt tgagctgctg
    17221 cttcactacc gatagcccct gcggtattgc cgttagaaag gattactcca ttgctataag
    17281 ccactggtgt agctgcatac tgagcttgag gagcagcctc ttgcacagca ggactagcta
    17341 cctcagaagc tactgattcc tgagctggtg ctgcatcagc agaggaaggc tctgcctgct
    17401 cagctggctg ctccttggtt gcagcctttg ctactgttga tttttttgtt ttatgatgtt
    17461 tcttcacaac cttagtatca gaagctttag cataggaatc agtgtttaca ttttcacttg
    17521 aaaaagcaaa aactactgcg agcaaagcaa tagcagctgc tacaatgcca aaactaaaat
    17581 aacgttgttt caaaatgtct tgtttaaaca ttaaataaat acctcacttt tctctgttat
    17641 ccatattaac tgttaattat tacttgtcta tttaagatat attaaaaata ttacagcaat
    17701 attgatattc caagttttct agcctgatat cagtgttttt tgagcttaag aagctcaaaa
    17761 taaaaacaat gcctaagttc agacctgtgt aacagatgat ttaagcattg ttattattaa
    17821 taaattctag ttgctacagc ctaacaaagg ggctgctgta atatagctag gtgagccttg
    17881 agggactttt tagacagaaa aggaaaatcc ccaaaatgac taccaaaata atggctagag
    17941 tgtcttttaa ttgccagctt agcaggcggt attttgttcg actgtcaccg ccttgatagc
    18001 ctctagcctc catagcgatc gctaaagcgt cagctctttt aaagcttgaa gcaaaaagag
    18061 gaatcaaaat agggataatc gactttacct tttgaataag attgccttct ccaaaatcaa
    18121 cacctcgcgc tttttgcgca ttcataatac gagttgtatc gtccatcaag gttggaacaa
    18181 accgtaagct caaagataac atcaaaccga tctcatgggc aggtacctta aacctaacta
    18241 aaggcttcaa cagcgcttca acagcatcag ataagcttag tggggtggtg gttagggtta
    18301 acagcgtgga aaagaaaata atcaaaacaa atcgcatgaa aatcaaaatg gcttgactta
    18361 atcccaagct tgttatctta attattccaa gctgaaaaag aactgatcct ccctgtgtaa
    18421 aaaaaacttg aaaaagcgtt gtaaatagga taataccaat cataggctta acaccattga
    18481 aaaagaaaga ccattttatc tgtgacaaga aaatcagcag caaggtaaat gctaacagca
    18541 aaagattagt taccacatta ttggcccaaa aaataatgat aatatagata atcatagcaa
    18601 gcagcttgct tcttggatca agccgatgaa taattgaatt cccaggaata tagcgaccaa
    18661 gaatgagttt atccatgctt taatacctct cttaattcct ccaaagtaat gggtaaatag
    18721 ggtaaatcaa agccttgctt agccaggcgt tgggcaaagg ctgtcacctt agggacacct
    18781 aattgttttt cttttagcaa atcaatgtgt tgaaaaatag cctttggctg acctgataag
    18841 atgattttac cagcttcaag gacataaaca aaatcagcat aattagcaac atcgtccatc
    18901 agatgtgtca ccagtacaat ggtcatgcct gattgatgga gcgatttaaa aagactcatt
    18961 aattcctttc gccctttggg atcaagccca gcagtaggct catctaacac caaaatatcc
    19021 ggctgcatcg caagaatacc cgcaatagca accctgcgca tctgcccacc agaaagctca
    19081 aatggatttt taccaaatag ttcctctgaa atccctacta gggttaattt ttcacgcgct
    19141 aaagcttccg cctctttctg agaaacacca aaattttgtg gtccaaaggc aacatccttc
    19201 aaaaccgttt cctcaaaaag ctggctctca ggaaattgaa agactagacc aacctgctta
    19261 cgaataggct taatatcttt attttttgac tgactagtta tctccttgcc tgctaccgta
    19321 accttgccgg tggtcggcag atgcaagcca tttaagagct gcataatcgt tgacttgcct
    19381 gagccagtat gaccaataaa agccgtataa gagccgtcta caatatcaag attaacgtca
    19441 aaaagggcac gcccctcaaa gggtgtccct gcttgatacg tgtagcttac attttggaaa
    19501 tgaattgaca tagctgttcc tctaattcct tttctgtgag atagattccc tgtatagggt
    19561 agccgtcttt ttttagcata ttaacaacag aggttgtaaa aggaatatct aaacctagat
    19621 tgatcaattg attgccccta gcaaatagct cctgtggagt cgagacagac tcaacacgcc
    19681 cattgttcat caccaaagct cgatcactaa gagccacctc atcaagatca tgtgtaatag
    19741 atataacagt tagttggtat tcttgtctaa tagattgaat tgtccgaatc aactccagac
    19801 gcccctttgg atccagcata ctggttgctt catctaaaat gatgatcatt ggccgcatgg
    19861 caacagcacc tgcaatagca acccgctgct tttgaccacc tgataatctg gaaggctcct
    19921 tatccttaaa agcctccata ccgaccagct gcaacgcctg atgaacacgc tctatcatct
    19981 cctgatggga aacacctttg ttttcaagac caaaagcaac gtcatcttcg acagttgcac
    20041 caacaaattg gttatcagga ttttgaaata ccatgccaat tttatgacga atgtcccaga
    20101 cattgtcctc tgtaagaaga tcaccatcaa caaaaatctg gccggcttct gctttcaata
    20161 gcccatcaat taacctaaca acggttgact tgcctgagcc attatgccca atgatagaca
    20221 accactcgcc ttgtttcaca tgaaacgtca catcatctag ggtatatcgc tcctggtcct
    20281 gcttatactt aaatgtaaga ttcttaactt caataatatt tgacattgtt atttaaaggt
    20341 atccttaaaa agaaagcttg ctcctttgaa ataatcgtaa cctgaataaa tcgtaaacaa
    20401 tagagcaata tacagcaaaa cagtgcctaa aacagtccaa tgacacagta aaaagatgat
    20461 ggaaagcatc tgtgctactg ttttgatctt accaggcata gcagctgcta ggaccttatc
    20521 tccagtctca accaatagca aacgaagtcc tgtaacagct agctcacgac agataataac
    20581 cgctgacacc caagccggta ccagctctaa gcccactaac ataataaaag cactcatgac
    20641 aagcatcttg tctgccaatg gatcagcaaa tttaccaaaa ttagtaacaa cctgccactt
    20701 acgtgcaagg taaccatcta aataatcggt caggcttgcc actgcaaaaa taatcgctgc
    20761 aaaggtatgc caaccgactg tctttgaaaa agaggtgatc aacaaaaaca atggaatcat
    20821 gacgatacgg gcgagagtta acaaattggg aatattttct tttttgatca tgcttatacc
    20881 ttattattgt atcttcagtg tgatatagct gatatcagta cttgtcattg ctgataaatc
    20941 taggggctga ccatcaattg ctactgaaac accctttgtt acgcctagtg tcaacaagga
    21001 ttctgttgtc tcagcaggca aggtagtaga ataagtcgga ttgtcctttg ttagggtcat
    21061 accagcctca ccaatttccg aattagtgag ggaaatccaa ctgctctcag catcagtcag
    21121 tgacactgta acatcaacag cttcttttga tttagtaata ttagcaatca agtaattctc
    21181 tgcgccctct gttgtgatca ccgtcttagg ctcagatgag ctggacgctg ttgagtgact
    21241 gctttgtgat gacttaagaa aagacatctc agcctctttt gctttttgac ctttatcaaa
    21301 ttgcttccaa acagcaaaac caataacacc aacaatagcc acagcaataa gacctagtaa
    21361 ggctgatgga aaggctgatt ttttcgtttt agcactattt ccataacgac ttagccttga
    21421 agcactggtc tctctagtcc gtctatggtc agtagcctta aagtgactag ctgtaggagc
    21481 tgatttgctt gaggatagtg acgtcttgac aggaatcact agggtttctg gttgagtcct
    21541 tgaaggctct ggttgagcta ttttttcaga atagctattc tcttgtagcc tttttttgct
    21601 gagcttttct tcaacgattt gtgtgactga tggtgtacct gtttcctttt taaagctcac
    21661 ctgcagctga tacaagcgtt ttaagctatc aaagtctaag ccaacaatat cagcatattg
    21721 ctttagaaaa tgaccaaact tttcttctgg aatgattttg aactggtcaa gctccattgc
    21781 caatagataa tgcgaggaaa tgccagtttt agcttcaatt tcgtctaatg ttatgttttt
    21841 tccgacacgt gtttctctta ataattcacc gagacttgtt tctctcatac gagtacctca
    21901 aaaatattgt aataagacca ttataacaga ttttaagcta tttgggaaag actgtaaaat
    21961 ctgaagtagc tgcatgctca aaaaacaagc ttcctatttc gataatatcc tttaaagcta
    22021 gggtctcaat aatcctagga atatcaaaat aggtctcttg ctctgataaa tgaaggctaa
    22081 attggcttgc cagctgatca atagcgtcta agctttgcat aaaatcccca tacatttcct
    22141 ttttcactag ctctaagtgc tcctcattaa cgtctcttga gcatctaaaa tcggaaatct
    22201 tttttctaat gctgttagac attgcaatag gctgactagt atctgaagaa atcaatacaa
    22261 attggaaatc cctttgaatg tcaacctcta tatcaaagga gtcgtctatc ttgccctttt
    22321 cataccaatc ctgataggtt tttgacgtcc agccaaggag caccgctagg agcagtctaa
    22381 gagctacctg ataggtgagt agagaatact cgcttgacat tagctgaccg cgaaagccga
    22441 ctgctaattt ggcagtcgca acgtccatat caatagatct agacttgatc acagggtagt
    22501 aggtcaatgg agctatctgt acatcatact gcgtctgact tggttgacta tcttgaaagg
    22561 cttcaatagc tgtaaaggct tcttcaatgt caatatcgcc aataatcgtt aagaccatgt
    22621 tagaagggtg ataaaaataa gcatggctgt cagccaataa agagcctgta atgtccctga
    22681 tagactcctt ggtcccagca atatcaacag ctaagctggt attgggaaag aggttctgta
    22741 agataccact gtaagcctga taatcaggat cgtcctgata catctcaatt tcttgagtga
    22801 taatatgttt ttcacgatta accgactcct ctgtaaagct aggagctgct acaaattcct
    22861 gcaaaagtct cagactttct tgccattcat tgacagttga aaagaaatag ctcgttttat
    22921 caaaggttgt aaaggcattt gtttctgatc ctaactgtgt aaatgtaaga gcaatatcat
    22981 taccatcttt atcctcaaat agcttgtgct ctaagaaatg agcaacacct gacggcaagt
    23041 caaacctttg acaattgact gtaaagcttg tgtcaagaga accaaaacga gcagtcagca
    23101 tagctgtttt ctcagaatag ccctctttct ttatcaaata aacccttaaa ccatttgcca
    23161 attgaccgta gtgtaaggtc tctttaatgc tgggatagtc ttttttcagt agtgacgtca
    23221 tcttattttc cctctaaaaa atatacagct tgcagcttga gtagattagc tgtcctgaca
    23281 atatctagct tgctaacctt gtcaatctcg tcaagccaac ttgacaaagt ataggaagga
    23341 tctatataag atctcatgta ttccagctca atcaaggctt tactattatc ctcagatagc
    23401 aaggcgttat tttttagcat tagctttgtt ttcttgacaa ggctgcttga aaagcgcccc
    23461 atcttgatgt cattgagctc tttaaccatt agctgcaggg ctcttgtccg gtgctgtcta
    23521 tctatgccag cataagcctc aaataagcct gtgtaaacat caaatcgact accaatacta
    23581 taggccagcc cctccttctc acgaatttgg gtaaagaagc gagagtgtgt aaaggctcct
    23641 aatagaccat ttaacacaac taaggcataa tactctgctt gcccataaac cagcggaaaa
    23701 tgataggcta gctctaaaac agactgatta agctgctttt gctcgaccaa ttcgttgaca
    23761 acattgacag gctgctgtaa ataaaagaaa tctagctttt tcctgcgtcc ctcaaaggga
    23821 aattggtgta acaattgtac catacgataa tcatcaaaat caccaagaat aaaaatatca
    23881 atctgatcct cattcaacat tttatgaaat tcttgatagc ttgtgtaggc tgtttcttta
    23941 gcaattaact cagtattacc atattttgac agcttcaggc tatcattagc ataaaataat
    24001 tgcttggctt ttagggcact ataataaaag gaatcctcct tatctgcctc gacataggtc
    24061 atcaaatgtc ttttttcgat gtcaaatagt ttgggctggt actgagccac tgataacaaa
    24121 ggagaaaaaa ggatatcctt tagaaattga atcatttcgt ctagaagctt ctctccataa
    24181 aaagcatact gatcctgaat aaaggtaatg tcaatatcca caatatgaac caaacccttg
    24241 gttgacacat gagttgacag gcttgctcca tacatttgtg ctaatttttc tctaaattgc
    24301 ttggcagtag gataggtatc gttagccgtt gctaacattt gagctactaa gactcgcttt
    24361 gctaccgttt tttgattcaa atcacctgaa aagcgaaacg ttatctgatt cgttttaaat
    24421 gttttgtttt ttatcagatg aagctgaact ccctgaataa gtttcataat atttccttat
    24481 taataaatgt gtgatctcta gaattatacc atttttatcg ctattcgttg agtgttaaca
    24541 tcagtctggt agcctatttt gactctttat caaaatgcta tcctgtggct atagtctaga
    24601 ctttagaagg tcagcatttc agcattatta tttagtggct ttttatgcta taatgacttg
    24661 aatgacaaat tggagatgac tatgacatac acactattta ctgactttat taccctacaa
    24721 gctttattaa aggagcaagg tattatccaa agtggtggtg ccattaaagg ttttttagct
    24781 caaacagagg tttttttaaa tggtcaagag gaacaacgac gtggcaagaa gctaagagtc
    24841 ggtgacgtca tcaccattcc atcacagcac atcaagattg agcttgtagc gcctagtcag
    24901 gccgaaaaaa cagcctatga agctgaaaag gcagaaaaag agcgagttgc taagatggtt
    24961 aaacaaatga atcaacaggc taaaaaagca cagaccaagc aagcagctac taccaaaagc
    25021 aagcgtggtc aagctacctc agctgtaaaa gctaagtcta atcaccaaaa gcctattcgc
    25081 ttcccaggat tgtagcatgt ggatcaaaga actaaacctc acccattacc gtaattatca
    25141 acaagcctca gcagcctttt caccgggctt gaatgttttc attggtgaca atgcgcaggg
    25201 caagacaaat tttcttgaag ctatttattt tttgtcagta acaagaagtc atcgcaccaa
    25261 atctgataag gacttaatct actttgacga aagggattgc tctatatctg gaactcttga
    25321 gcgccttagt ggtcgtgttc agctagaaat actgctgtct gataagggac ggatcaccaa
    25381 gattaacacc ctaaagcaag caaagctttc tgattatatc ggagcaatga tggtggtcct
    25441 ctttgctcct gaggatctac agctggtcaa aggctctcct aatcttagac gaaaatttat
    25501 ggacattgac ttaggtcaga taaagcctgt ttacttatca gatttgtcac attacaatca
    25561 tgtcctaaag cagcgaaatg cctatctcaa aagtgttcat cagcttgata atgacttttt
    25621 atctgtgtta gatgagcagc tggttaccta cgggagtcgt gtaatggcgc atcggttggc
    25681 gtttgttcaa tcactagcaa aagaggcaaa caagcatcat caagctatct ctaatggcct
    25741 agagaagctt tcgatctcct atcaagcctc tgtgagcttt gagcaccagc aagagattta
    25801 tcagcaattc atgaaccagc tcaaaaccac tcatcaaaga gatttcttga gaaaaaatac
    25861 tggtgttggc ccccaccgcg atgatctggt tttttatatt aatgacatga acgctaattt
    25921 tgctagtcaa ggccagcatc gtagcctgat tttatcactg aaaatggcag aggttagtct
    25981 gatgaagcaa ttaacaggtg acaaccctat tcttctactt gatgatgtta tgagtgagtt
    26041 agacaatacc agacaaacaa agcttctggg agctgtcaag aaagaaaatg ttcaaacctt
    26101 tatcacaaca actagcttag agcatttgtc tcagctacct aaggacatta gtctctttaa
    26161 ggttaataaa ggaacaatag aacgagattc tatcatgatt gattaactga gcaaactaaa
    26221 aaaagggcac cttaatagtg acccttttta cggttaaatt agttgatact ctatgatttg
    26281 acgataccta agaggatagc gccaacaata aagcaaagga tacctgtaat gacccagcgc
    26341 atctcttttt tggtttttgt ctcacctaag aataaaatac ctccgacaat agagataata
    26401 gcgcccaatt gtgaaaagct aaaagcaatc gccagaccag cctttgaggc tgctagcagc
    26461 atgaagatat ttccaactcc ccaaagcaag ccaacaacac tatttttgat aacatactgg
    26521 tcaaacgata ccttaaacga cataaacatg gctgcaccaa gcaccattcc cactgccatc
    26581 ggtaaaataa ccgacaacac atcaaatttc ataatgttat tgaacagcac agcatacatc
    26641 acatagccgg ttgtcgagta ggttaaggct ctaaagccct ttgaaaaatc atgcaattga
    26701 ttacttgctg cattcgtctc gtcctgcttg cttgaaaaat aaaaaccaac aatcaaaaga
    26761 agtaaggcaa tcgtaccaac gacaaattga ataggcttgg tccactcatg aaagaccagc
    26821 acaccaatca ggctacctaa aactagctga gaaccactag acaagggatt tgctactgaa
    26881 acacccatat actgcatggc atgaaattgc ccagtctgac caacagacca gataatacca
    26941 cctaaaatcc caaaaatcca gagcttcata gacatctcag gtctgactac taaccaaaca
    27001 actagagcaa atagtaaagc tcctatggtc attccaaagg tctgctgtga gggtttaccg
    27061 ccaattttat tactaacaaa gccaatactt ccccatgcaa acattgggac aagtgcaaat
    27121 aaaatacctt ccaaatttac atctccttta caataagttg acacatgatg ttaacgataa
    27181 aagtgctttc atacggagaa ttattatagc ctatttcctt agaaaataca ataacatgat
    27241 gtaaaaaatc atctgctcac acgcttctcc ctaaaaaggt gtcaaagtag ctgacagagc
    27301 ttatttactg caatgctaga ggattattta atgaaaaccg tttgacctta tggctggctc
    27361 tagctggagc tttgttaggg acttttgtga cctgagttcc aaagcaatca gcaactagct
    27421 gactgaaata gcctaagcgt ttgaggagta gagcaagatg attaaccata gcactagctg
    27481 cttgaccgga catgcttgct tctatggtag ctttgacaaa ggatagctca acgatgattt
    27541 tatccagcag tctgccaacc atcttttgac tagtgatgat gtcatctaaa tcaagagcgc
    27601 tgtaaactcc tttttcgatc aatcgactga gatctccatg caagttttga agccgatgcc
    27661 ttgcggtatt gactcgctgt atcgtatcag tcaatgccgg tactagagga catacctcag
    27721 ctctggcaga agcaataccg gatcttatgc ggcaaggata taaagcaccc agatttcccc
    27781 aatagctcct tgtcgttgta gaggtttcat ctttgatttc tgttcgttca acataaaccc
    27841 tatctgaaaa acgtctctct aatactgtca cgatattctt aaagatattc acctcagtag
    27901 tccaataatc aagtgtatca aatagccttg aaaaggttga cgcataaaca gaggcaacct
    27961 ttctggaata gtcccgactc ttttgttcca cctgctcatc aaaggcttgg agaatatctc
    28021 tgacatcatc taaaagacct gttctttcta ggtaagcatc atagctgctt gggacacaga
    28081 cgacatcagc acttccttga aattgaccat tttttaggct gttgcctagc cagttatctg
    28141 tagctgtgac attttgtgat acccctagga tcagctcact ggtattgatt atcatttttt
    28201 ccagctctat gatatcctgt aattccacgc taaatacctc ttttaaggaa tcgctaatac
    28261 cgtcaacttt actttcacgt aaacccgttc cttcaaaggt cttatcactc tccttcaata
    28321 gctgacgact ggcctcatca ataatctgcc aagatttcaa aagtgtcgag cgaccgataa
    28381 tactatcaat ccagcctgac ttttcatgct gagcagatga ggcaagctga agcgattttg
    28441 tgtttaagct cgctaattct gaatcataca tggccagatt gaggcgatta ttattcacat
    28501 atgggatctc atcataggaa aagggatagt ctaggctagc cgaatgagac agcatatcaa
    28561 acaagtcctg ctgaccaact aatctctcca aagaactttg caggctatta aaagtatcgg
    28621 ttaggccatt tgtagcaagc agggctttga tgttttctga aactcgcttt ttcctctctt
    28681 caaaggagtc ttttatggca tcattttttg cctgacattt ttcagtaatg tggcgaatcg
    28741 tttgcaggtc gcctgatata gaggattgaa ggttttgtgc aaggttagtc aggacaccag
    28801 cattgatgac aatcgtttgc ttatcagaaa gcacaccgta ccgagccgat gttgacgaat
    28861 caaagtaatt tctaaagcct aagtacagct cctctacctt agtgtctaat cggttatcgc
    28921 tgtcaatatc aataggcaac aggacattag catgaacaaa ccggccattt acgtctgtca
    28981 tgttgccata ttgatcatac tgatagccat gccacatatg ctgtaagact atatcattga
    29041 ccttttttgt attgacaaca aagacctgac cgactgctcc ctccttttgg tcaaagccca
    29101 taccaatgat gtcatgcgga tccacatagt tgtaaatgcg gtcatgcaag agctttgcac
    29161 gttttctttg atactcatta agcacacgat aggtgttggg gccattgtag atatagactc
    29221 cagagatacg agataagttt ttatcactaa cagaggtaac accgtactga actgtcatgg
    29281 agcctagcga atgaccataa aactcaaatg ttgcgttagg gtattgcttt aatgtcttat
    29341 tggtaaaggt tgctgccttt cggagctgag ctgtcccttt agttggtgtc tggtccggta
    29401 aaagaatgcg catagccata ggcaaatcat tgcctaccca atctgcaacc acatctactg
    29461 ggtgtttctg ccactggtct gggccagtag agccccggta cagcatggtg acatgcttga
    29521 cctgagcata gtctgccttg gtaggatgag ggggaagctt gacatctgtc acgacatagg
    29581 cttgaaaacc tgatatcgaa tcctctatct gagacacata accgatggaa aactcagaat
    29641 tatcatcatc aattaaaact ggtgaaccta ctgtatgttt ttcatactct tcctcagcaa
    29701 tccgttgtct ctgttcgtct gtcaggatca tcattttcac tctcctttta gtagtttttc
    29761 taacttttct gagcgataat tactagcgat ctctaaattt ctttctaaat catatctact
    29821 aaggcgaacc cttaaataag tatctggatc atcattgata atcaggtgaa tagaaaaacc
    29881 tcccattgga ttaata
//
LOCUS       DARYMD010000028        28033 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYMD010000028 DARYMD010000000
VERSION     DARYMD010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28033
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(298..813)
                     /locus_tag="TU818_001153"
     CDS             complement(298..813)
                     /locus_tag="TU818_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL0923975.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAIIPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLIHIGVDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVSLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAARA
                     EVGQVRLKATL"
     gene            complement(815..2326)
                     /locus_tag="TU818_001154"
     CDS             complement(815..2326)
                     /locus_tag="TU818_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL0923976.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTDLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTNTQSSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            complement(2316..3041)
                     /locus_tag="TU818_001155"
     CDS             complement(2316..3041)
                     /locus_tag="TU818_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL0923977.1"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRSIRKKYPEQLFMADISTLEEGLVAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEEKSHGF"
     gene            complement(3570..3992)
                     /locus_tag="TU818_001156"
                     /pseudo
     CDS             complement(3570..3992)
                     /locus_tag="TU818_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678587.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4136..4642)
                     /locus_tag="TU818_001157"
     CDS             complement(4136..4642)
                     /locus_tag="TU818_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923978.1"
                     /translation="MTQTFFNNDVDERRRQLYLDARSKGHLEKCFRGDSGFKINAKDS
                     YFQSITDINVLIERCLYPLYDLGDSIIPHETERILSQFSTSKNVVELYQVVSYIFYQK
                     NNKLLKKNFSFYIDFNPMIPDLVFSVKRLSPENIVTDDEKAMVGFIKNMFQKIPQVQS
                     YLEAQNCK"
     gene            complement(4644..5570)
                     /locus_tag="TU818_001158"
     CDS             complement(4644..5570)
                     /locus_tag="TU818_001158"
                     /inference="COORDINATES: protein motif:HMM:NF019104.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923979.1"
                     /translation="MNEPIAARVTKPTYNRQQLLKNLENSRLATESSRFKSYVAREKL
                     INTLRKQNADLNLITFREKAIEIFNRDLKGNSWVSIRQADEFVETLDDYAQLSVDNGA
                     VSTKADFYKMYSNKNYIYLDGFIKNIKQLYIKTGASSIVNGQDLYNAIEQYGTIGRGK
                     SGNFATSMAEDIALLYDSSGNLVSSGMIEAIKGVDEGKYLSGAFQYEYSPQFVKSFDQ
                     IGEVRTVTGKTPGSSLLNIPGAKTWAGKNMALSQSELMMPSIDTSNLKLEDVLLSMES
                     TGIYTLNNPTIVLKDGTKKIVEGQFIIRKLGN"
     gene            complement(5712..6134)
                     /locus_tag="TU818_001159"
     CDS             complement(5712..6134)
                     /locus_tag="TU818_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923980.1"
                     /translation="MEHSQLEWEDVSQYEEVKGYGQQVWKRQGTYYLVTNEGGIAEQR
                     VVYELPYDLFELLEQGKRNLGEIAFKLRYDCWPPTEEEKIASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
     gene            complement(6457..6717)
                     /locus_tag="TU818_001160"
     CDS             complement(6457..6717)
                     /locus_tag="TU818_001160"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923981.1"
                     /translation="MDNNNCFQYTQRLRELIELEYPKQKNYSGILRDLYVLTNDIDNN
                     RIVGNINFSSLARQFVDDTTQYDSPILKTLKDLEVCLNRKRR"
     gene            complement(6732..8540)
                     /locus_tag="TU818_001161"
     CDS             complement(6732..8540)
                     /locus_tag="TU818_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923982.1"
                     /translation="MSYNIKYDEITSLQQSTQTTISAWGDGITSIQTALSALIGDSRL
                     QGQTASSIKSYLSEVHGTLLQTLQSLMNDYSASLLLYKDGYYQIDSNSHAQLPGQVFK
                     TLQSELRLSQAHLKDQLELLQNTRAKLSDLVHYSGVSHAKTVVDYSELITDIHRLDEA
                     IIQYESNHASQDLAAFKELLASTKALIAEYSSKPKRAGSYQVGDIGQLNTIKRFATAY
                     QGVARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLVTIAVGVAAIVMT
                     AGAATPLVVGAFVVGSGTVAYGASNLYEAGHNIYLGSVGDGLTVATNPLRDTLFMGND
                     RLYHQIGGLFTTASAALILIGQTKSVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSE
                     QDAQRATLVGNILAGYAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARES
                     SNFGGYIKKESVTKYPTQIDSKVTVGAKENLPGWIADSFTDSHYRTVITGEEITLYRT
                     FGGASDAGGGFVTTVPATNRIQAKIDTALLPEWKNTRQYEAVIKIPKGSQLNIGKVAP
                     QTVKSSGTTLIGGGDQVLLPNRWPLEWIQEIRIVPN"
     gene            complement(9181..10080)
                     /locus_tag="TU818_001162"
     CDS             complement(9181..10080)
                     /locus_tag="TU818_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL0923983.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRSVPEEINRQNAPVINPDEVELEEMKAVRSQDRRA
                     AESDAHQPTGPLSTAQSAPTQSKAQPVSSAAGASQLDPAAADMSKDIELAAQEISDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            complement(10092..10901)
                     /locus_tag="TU818_001163"
     CDS             complement(10092..10901)
                     /locus_tag="TU818_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL0923984.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLTRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPVFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TU818_001164"
     CDS             complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TU818_001164"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL0923985.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKSEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            complement(11736..12476)
                     /locus_tag="TU818_001165"
     CDS             complement(11736..12476)
                     /locus_tag="TU818_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0923986.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            complement(12480..13778)
                     /locus_tag="TU818_001166"
     CDS             complement(12480..13778)
                     /locus_tag="TU818_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL0923987.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGTCFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     SSIRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPETLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            complement(13790..15136)
                     /locus_tag="TU818_001167"
     CDS             complement(13790..15136)
                     /locus_tag="TU818_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0923988.1"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLIIDPLLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGSYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDPFLDLKSPIMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     FLKQELKKEQQAYIANLETYGKHLEKLYKGVKVFQLVYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDRI
                     RDSYISELDLLLLVSIFCDNAIEAALETAQPAVAIAYFLSDDQQIFTVTNTTKDERVM
                     ISRIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
     gene            complement(15581..17026)
                     /locus_tag="TU818_001168"
     CDS             complement(15581..17026)
                     /locus_tag="TU818_001168"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL0923989.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSAYEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDEIRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            complement(17628..18341)
                     /locus_tag="TU818_001169"
     CDS             complement(17628..18341)
                     /locus_tag="TU818_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL0923990.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            complement(18469..18975)
                     /locus_tag="TU818_001170"
     CDS             complement(18469..18975)
                     /locus_tag="TU818_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL0923991.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            19358..19636
                     /locus_tag="TU818_001171"
     CDS             19358..19636
                     /locus_tag="TU818_001171"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0923992.1"
                     /translation="MKQTKIICLLAAAAVLTLGPISTGQTQPQTVYASQVSGDSCIDL
                     GNGWFKCPKDIGGWDILFNQDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TU818_001172"
     CDS             complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TU818_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL0923993.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHINGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGDIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDLPKGIEVVGVTTVGEVLKA
                     VFT"
     gene            complement(21225..21671)
                     /locus_tag="TU818_001173"
     CDS             complement(21225..21671)
                     /locus_tag="TU818_001173"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL0923994.1"
                     /translation="MTRIRGFELVSGFTDTDLLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            complement(21873..22640)
                     /locus_tag="TU818_001174"
     CDS             complement(21873..22640)
                     /locus_tag="TU818_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL0923995.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKVWARESIRPRILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFVKTVRGLEKESEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAANI
                     QGIDLVQVKKDAKAFMADKDLEADFPRIRFSYAGKEI"
     gene            complement(22802..24598)
                     /locus_tag="TU818_001175"
     CDS             complement(22802..24598)
                     /locus_tag="TU818_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923996.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLAYLFTAVANLIYSLLFTR
                     VISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLLNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGAGRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISAPKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQKEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            complement(24598..26307)
                     /locus_tag="TU818_001176"
     CDS             complement(24598..26307)
                     /locus_tag="TU818_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0923997.1"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDTFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PSISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            complement(26300..26749)
                     /locus_tag="TU818_001177"
     CDS             complement(26300..26749)
                     /locus_tag="TU818_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL0923998.1"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            26959..27978
                     /locus_tag="TU818_001178"
     CDS             26959..27978
                     /locus_tag="TU818_001178"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL0923999.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHT"
BASE COUNT         8373 a         6755 c         5154 g         7751 t
ORIGIN      
        1 ctctattttc ctttttcagc ccttgtatac tggggaggat ataatagccc ccctaaaata
       61 aaatgtgcta agcaatatga gaaacaggtc gctgagcttt tcttttattt gccacaaggc
      121 acatacgaca gctgttaaca tttaaataga ggttaaaaga taggacaatc aaagcctgct
      181 gattgctgac aataataaaa gcaccccaag gcattgaccg acttagccaa gtgctggggt
      241 gcagtttttt catatgacct tttagttgtc atcaaggact ggatcgatag cctctagcta
      301 gagagtagcc tttagcctaa cttggccgac ttctgcccta gcagcaactg ctccagcatc
      361 agcaagacgc atatcagcaa tgtcctgtga gtttgtaaag acaaccataa cggtgctgtc
      421 tttttgagca gcttcaagca ctggcaaaga gacctgagcc aataactgcc cagctactac
      481 ctcctgacca gcaacaatat cagagctaaa ggcagcttct cccagctcaa cagtatcaac
      541 accgatatga atcaagacct caagaccagc tggagtaacg atgccataag catgcttggt
      601 cggaaaaacc gtcatgaccc ttcctgttac gggtgcataa atagcgccct cctgaggaat
      661 aatagcaaag ccatcgccca ttagcctttc tgaaaagaca ggatcactga cactggtaat
      721 aggaactaat tgtcccttag ccactgataa aatacgatcg cttaacgcat cagctttttt
      781 tgctgataat aattgcttcc acttctttat catgttaatc ttctctacct aatagttgat
      841 tgatttcttg actatacaag atagccttac caccataaat agcctgaatg ccatttttaa
      901 catctaatac agctgttgct cccagtgagg ttaaaacatt cttgttaacc aagctgctat
      961 ctgacagaga cactctcaag cgagtcgcgc aagcggttac atcttcgatg ttagcttgtc
     1021 ctcccaaagc ctcaataata gctaatgaca cctcacgaag tgatgagctt tgagtattag
     1081 tagtctctgc ttgtccttct gcttctacct gagctaccat tcccggtaca gcaacctgga
     1141 atttgctcac aaagaattta aagacaaagt aataaaccat aaaccacacg ataccaacag
     1201 ggataacaag tagccagttg gtatgatcat ttccttggaa cacaccaaag attaaaaagt
     1261 caatcaaacc acctgagaag gaattaccga tacgaatctt taataaatca gcaactaaga
     1321 aagaacaacc atctaagaaa gcatgaacta catagagcca aggggctaca aataaaaagg
     1381 caaattcaat aggctctgtg atccctgtta gtaaggaagt caaggcacta cttgaataaa
     1441 agctaccaac ctttttacga ttagcctttg gaatagcgtg atacatagca agacaggcag
     1501 caggtagtcc aaacatcatg gttgcaaaac gtcctgcaaa aaagcgtgtc ccgtaagtaa
     1561 acaagtcggt atggttagca tcagccaatt gcgcaaagaa gatattttgt gctccttgga
     1621 tagtctcacc tgctacaacc tcactaccgc caagtgatgt ataccaaaac attgggtaaa
     1681 tggtgtggtg cagccctact gctcctgtca gacgtaaaaa gaaaccgtac aagaatgttc
     1741 cgatgctccc catatccgca attttttcac caaacactac taggagattt tgaataggtg
     1801 gccaaatgac atagaaaaca ctaccaatca caatcgctgc caatgaggaa acaatcggaa
     1861 taaaacgaga gccgccaaag aagcctaaaa aggctggcag ttcgatcttt cggtacttat
     1921 tgtgaaggct aacaacaact aagccaaccg tcaaagcccc taaaacaccc gtatcaatct
     1981 gagcgtcctt tgctgaaaaa agagtcagat agccgctaat ggttgccgta aagaccaaat
     2041 aagccacagc acctgaaaga ccggctgttc ctttatctcc gttggctaag ccaacagcaa
     2101 caccaatcgc aaaaatcaag gcaatattag caaaaacagc gttacctgct gtgctcataa
     2161 tggtaaaaat agcctgtagc catgcttgat ttaatatcgg aaattgtgca atggcattgc
     2221 tatttgacag ggccccacca atccccaaca acaaaccagc aactggtaag attgagatcg
     2281 gcagcataaa ggcttgaccc aattttgaaa atttcttaaa atccatgtga tttctcctcc
     2341 ttcttgagag ccgccacaaa gcgctctgca atttcctttg gtctggtaat agcaccacca
     2401 accacaatac cagctactcc caaagcctga acagccctgg cctcctctgg actatgaatc
     2461 ttgccctcag ctatcactga tacccctgca tcacacaagg cacttatcag ctccatatcc
     2521 ggacctgtcc cctgacgact ataaggcgta taccctgata aggtcgtccc tacaaaatct
     2581 ataccagcct cataggctac tagaccctct tcaagcgtac tgatgtctgc cataaacagc
     2641 tgctctgggt acttcttcct tatcgatcga ataaagtccg ctatcgctaa gccatcatga
     2701 cgctcccttt gcgtacaatc caaggctatc accgctacat ctaaggccgc taaggcgtct
     2761 acctctgcca tggttggcgt gataaagggc gcttgcggag gatactcctt tttgatgatc
     2821 cctatgattg gcagatccgt caccgcttgg atttccttaa tatctcgaac cccattagct
     2881 cttatcccta ctgctcctgc ttcctctgct gcctttgcca tcagaggcat gatacctcct
     2941 gcctctgaat agagaggctc gcccggcaga gcttgacagg aaacgatcag cccgtctttc
     3001 agagctgtca gtagctctgc cttgcttggt ttttcaagca tgctttctac tccttttatt
     3061 aattttagag aacgttcaca tctttattgt agcagatatt aaaacacttt caatagacag
     3121 cccactttta ggaagtactt tcattttcag agaaaaatcc ttgttttctg aaagtatatt
     3181 caatagcctt aagtatggca aagagctagc ctattgagct atttactaat tgatacaaca
     3241 acagcaaaac cttacaagac ataccttctt accataaaag cctttttgcc agccagctaa
     3301 ggccaaatac ggcaatatgt ctcaacaaga actaccttag gtcctattat tgcttgataa
     3361 gcttgacaaa gagacaaaaa agagagaacc agtccagtcc tctctcgcac ccagcttttc
     3421 aagctctaca atacccgtag tgggtaactc caccgcaagg gttatatata gaacttttga
     3481 ttgtacccaa aaataaccac ttttcaccta cctaatacag ctaacaacgg cccctaacat
     3541 agctgccctc agatccgcta tcttaaacat tatttcaaag gactgacata atcatctggc
     3601 agttttccct tccaatctat ccatttttgc tccgcaattg gaattagttt tcttagctct
     3661 tcttaggtaa acagttccca actggttgga tctgcaatta atgctattgg ggatctttgt
     3721 agaaatgctt tatcactagc tattttctcc tcttctgttg gcagccagca gttatttttg
     3781 acataaaaat ctatttctaa taaaaatttt cggtcacttt ccagtaattg gaaaagctca
     3841 ttagggagtt tatacactac tcgttgtaca gcaattcctc cttcttctct gactagataa
     3901 tattctccct gatgcttcca aacctgttgg ccataaccct tgatttcctc atattgacta
     3961 acatcttccc atgttaattg actgcgtgcc atgtgtgtta tctttcgttt ttatagctta
     4021 atcgataaat actgctcaat ctttttccaa taataccctt acctcgtctg attgaaaagc
     4081 atactctatt tttatttaag ctatttcaaa tccatttttc aagtattcat ctaaactatt
     4141 tgcaattttg agcttcaaga taagactgta cctgaggaat tttttgaaac atgtttttta
     4201 taaaaccaac catcgctttt tcatcatcag tcacgatatt ttcaggagat aaccttttaa
     4261 cagaaaaaac taaatcaggg atcataggat taaaatcaat ataaaaggaa aagttcttct
     4321 ttagtagttt gttgttcttt tgatagaaaa tatatgacac aacttgatat aattctacaa
     4381 cattttttga agttgagaat tgagacagta ttctttcagt ttcatgtggg ataatgctat
     4441 ctcctaaatc atacaaggga tacaagcagc gctcaataag cacatttata tctgtgatcg
     4501 attgaaaata tgagtcttta gcatttattt taaacccaga atcccctcta aagcacttct
     4561 ctaagtgtcc ctttgaacga gcatctaagt aaagttgtcg acgtctttca tcaacgtcat
     4621 tgttaaaaaa tgtttgtgtc atattaatta cctaattttc taattataaa ttgtccttca
     4681 acaatctttt tagtgccatc tttcaaaacg attgtaggat tattcaaggt ataaattcct
     4741 gttgattcca tacttaataa tacatcctcc aattttaagt tactagtatc aatagatggc
     4801 atcattaatt cagactgtga caaagccata tttttacctg cccaagtttt agcccctgga
     4861 atatttaaaa gtgaagaacc tggagtttta ccagtaactg ttctcacttc accgatttga
     4921 tcaaaagatt taacaaactg aggactatat tcatactgaa atgcaccaga caaatactta
     4981 ccttcatcta cccctttgat agcctctatc ataccggaag aaactaaatt accactacta
     5041 tcataaagta atgctatatc ttcagccata cttgttgcaa aatttcccga tttacctctt
     5101 ccaatggtac catattgctc aattgcatta tacaaatctt gaccattcac aattgatgat
     5161 gcacctgtct taatataaag ctgttttata ttctttataa agccatctaa atatatatag
     5221 ttcttatttg aatacatctt ataaaaatct gcttttgtag aaacagcacc gttatctact
     5281 gataattgag cataatcatc taatgtttct acaaattcat cagcctgtct tatcgaaacc
     5341 caactatttc ctttaagatc cctattaaaa atttctatgg ctttctccct aaatgtgata
     5401 agatttagat cagcattctg ttttcttaaa gtattaatta acttttctct tgctacatag
     5461 ctcttaaacc ttgagctctc tgttgccagc ctgctgtttt caaggttctt caaaagctgc
     5521 tggcggttgt aggtcggttt cgtcacccta gctgctattg gctcattcaa gctaaaccgt
     5581 ctggcggcgc ttggagacgc ttggcattgg cttcaaggtg acgagctact ccctgataag
     5641 ctgtcgcagg ctaattatta agaacatgct ttaaaatagc agagctaatc tcggctccgc
     5701 tatcttaaac attatttcaa aggactgaca taatcatctg gcagttttcc cttccaatct
     5761 atccattttt gctctgcgat tggaatcagt tttcttagct cttcttgggt aaaaagttcc
     5821 caacttgttg gatctgcaat taaggctatt ggggatcttt gtaaaaatgc tttatcacta
     5881 gctattttct cttcttccgt tggtggccaa caatcatatc gcaatttaaa agcaatctcc
     5941 cctaaattcc gttttccttg ctccaataat tcaaataaat catacggcag ctcatatact
     6001 actcgctgct cagctatacc accttcatta gtcactagat agtaagttcc ctgacgcttc
     6061 cacacctgtt gaccataacc cttgacttcc tcatattgac taacatcttc ccactctaat
     6121 tgactatgtt ccatgtatgt tctcctttac ttgtactgat atctttcata actccctctg
     6181 gcatatcacc cggataagta cgacctccag gtcgccacca gctattagca cccttttcat
     6241 taccacttgg aatagaaatc cctttctccg aaacaacctc tggtgaaaca tctaagcgat
     6301 agagcggatc attgccaaga taaccctcgt cgaagccgag taagctttca taaaagattg
     6361 atgcatagtc agcttactct tgttcctcct ttcttcagtt ttttatcata atttcatctt
     6421 aaaatttaat caattcgagc aatctaatct cactcatcat ctccttttcc tatttaggca
     6481 tacttctaag tccttcaaag tttttaaaat tggactatca tactgtgttg tatcatcaac
     6541 aaattgtcta gctaaacttg aaaaattaat attcccaaca atccgattat tatcaatatc
     6601 attagtcaaa acataaagat ctcttaatat tcctgaatag tttttttgct tgggatactc
     6661 aagttctatt aactctctaa gcctttgtgt atattgaaaa cagttattat tatccataaa
     6721 tttctccttt tttagttagg aacgatcctt atttcttgaa tccactccaa tggccaccga
     6781 ttgggaagta agacctgatc tccacctcca attaaggttg ttcctgaaga tttaaccgtc
     6841 tgtggggcaa ccttgccaat attcaattga ctcccctttg gtattttaat tacagcctca
     6901 tattgtctag tatttttcca ttctggaagt aaagctgtat ctatttttgc ttgtatacga
     6961 ttagttgcag gcaccgttgt gacaaaaccg cctccagcat ctgacgcccc tccaaaagtc
     7021 ctataaagtg ttatttcctc acctgtaata actgttctat agtgactatc tgtaaatgaa
     7081 tctgcaatcc aaccaggaag attttcctta gccccaactg ttactttact atctatttga
     7141 gttggatatt ttgtaacact ttcttttttt atatagcctc cgaaattaga actctctctc
     7201 gccagcctgc tgttctcaag gttcttcaaa agctgctggt gattgtaggt cggtttcgtc
     7261 actctagctg ctattggctc attcaagctg aaccttctgg cggcacttga ggcggcatag
     7321 cctgctagga tattccctac caaggtagct ctttgggcat cttgctcact gccgcctaag
     7381 agcttggtgc catgatagct ggcctgacca ccgataaagc cgccaacctc accgatcgta
     7441 aactctgtca agcccttggc aacactcttg gtctgaccaa tcagaattag tgctgcactg
     7501 gctgttgtga acagcccgcc gatctggtga taaagcctgt cattccccat gaacaaggta
     7561 tcccgaaggg gattggtagc cactgtaagc ccatcgccaa cgctacctag ataaatgttg
     7621 tgcccagcct catacaggtt cgacgcccca taagcaactg taccactgcc aacaacaaag
     7681 gccccaacca ccaagggagt cgctgcccct gctgtcatga cgatagccgc aaccccaacc
     7741 gctattgtca caaggctgag tgctagatct atccagccct gcttggccct gtcctctgca
     7801 gctactgcct caaaacgggc atgatcccgc tcctgcgctg cttggagacg cttggcattg
     7861 gtctcaagat gacgagccac cccctgataa gctgtcgcaa agcgttttat ggtgttgagc
     7921 tgtcctatat ccccaacctg atagctccca gcccgcttgg gcttactgct gtactctgct
     7981 atcaaggcct tggtcgaagc caaaagctcc ttgaaggcgg ccaagtcctg actggcatga
     8041 ttgctttcgt attgaatgat ggcctcgtcc aagcgatgga tatcagtgat cagctcacta
     8101 taatccacta ctgtcttggc atgactgaca ccagagtagt gaaccaggtc tgataactta
     8161 gctctggtat tctgtagtag ctcaagctga tccttgaggt gggcctgcga gagccgaagc
     8221 tctgactgca gggtcttaaa gacctgaccg ggtaactggg catgactatt actgtctatc
     8281 tggtaatagc cgtccttata cagcaagagg ctagctgagt aatcattcat caggctttgc
     8341 agggtttgta aaagtgtccc atgcacctca ctcagatagc tcttgattga gctagcggtc
     8401 tgaccctgaa ggcgactgtc tccaatcaag gctgacaggg cggtctggat actcgttatc
     8461 ccatctcccc aagcactgat cgtggtttgg gtgctttgtt gaagggaggt aatctcatca
     8521 tatttgatat tatagctcat ttcttcccct aacgttttca atgcgatatc aaaatgtttc
     8581 accaataata gcaatacatt tctttaatat acctctttta ttatatcaaa aaaaacttaa
     8641 tgattatcac accaagctaa gagcattgat gggtaataac atatagctta tccaaccttg
     8701 ttagcaggag tattacaaat aatgtattgc caagaggaaa agctgatata aataggtggg
     8761 acaaacgtgg tcaagaaaac ctttaacacc aagaaaacca tgataattct tgataacatc
     8821 aaatagtgcc tcagctaaat gattatgatg acctttacca aatcattctt tattatctgc
     8881 aagaaaagaa cagtgacatc tcttcgatcc gattacgaat ataaatcaag cttcaaaacc
     8941 gctcttagta cctttattcg ttgccaaaaa tatctcattg aactctctta ttcaaacgct
     9001 aagctagaag caaccaataa actgagcaaa aacataaagc ggcaagcttt ggctttagga
     9061 acttcaaagc taagattccc aatactttta acatcacaaa agagagcacc aagctggtcc
     9121 tctctagata ttagttatta gtcaccccac tacagttgac attgagcctc tttgatgaca
     9181 ctagtcgtga attagtgaga caacaacata gcgattaggg tcgttgccct ctgaatagct
     9241 ctcaacccca tcaatagcag aaactgtttt atgaacaatc tttcgctcgc tgttactcat
     9301 aggatccatg gtataatctt gaccagactc aagcacacgc ttggatacct ttttggtaaa
     9361 gtcaatcagg gtttctgtcc gatgctctac ataatcatga acattcaagg agacagaaaa
     9421 attcttagaa tagcggtcat gtaagaaatt ttgggccagc aattgcagtg atttcaaaac
     9481 cttaccatga tagccaataa cacgacctgc ctctggtgtc tctatctgaa gattgatctg
     9541 acgacgattg ttggtcctct caatagaggc ttcaatatcc atctcataga taatcttggt
     9601 cacatagtca gaaatctcct gtgcagctag ctcaatatcc ttactcatgt ccgctgcagc
     9661 tggatccagc tgactcgcac cagcagctga cgacacaggc tgtgcctttg actgagtagg
     9721 agctgactga gctgtgctta atggacctgt tggctgatga gcatcagact cagcagccct
     9781 tctgtcttgt gatcgaacag ccttcatctc ctcaagctcc acctcatcgg ggttaataac
     9841 cggtgcattt tgacggttga tctcctctgg aacactacgt acggcttttt tatcagcctt
     9901 atagactgtt ttttcattaa tgccttcaat atcaacctga gctggctttt taccaaagcc
     9961 caaaaagccc tttttctcct ttgaaatcac cttgatgtgt gcttttagac gtgacaaccc
    10021 caactcttga agtccttttt caattgcttc ttcaacagtc ttacctgtaa acaataccat
    10081 atcctaaact cctattttct tttcattgct ctcttacgag cgcgacgttc cttagctcga
    10141 cgctcttttt cttcatctgc taaacgttgc ctttcggcaa taaccttaaa gggattatta
    10201 aacagcaaga gctgaacaac ctgaaaggca ttggaaactg cccaataaag caccacacca
    10261 ctggccagat taaagcccat aaagaagatg aacacaggca tcacgtaggt catgatcgtt
    10321 atcatggccg tcttttctct agccgctaga ttggttagcc atgttgataa aaaggtaaag
    10381 acagccgcta aaataggcag aataaagaga tgatcatgtc gcgccagctc aacccataaa
    10441 aaggtgcctt ctcttaagaa agccacacga gtcagagact gaaacaaggc aaacatcacc
    10501 ggcatctgaa tcagcaaggg caaaaggctc atgtaaggat tgacaccata ctttttgtac
    10561 agagcttgac tttcttcagc tagcttcata cgagttgctg tgtctttagc agcatatttt
    10621 ttttgcaggg cctttagctc tggttgaatg tcctgcattt tctgccctga cttgatttgc
    10681 atgttaaaca atggcagtaa aagcaagcga atcattatcg taaataggat aatcccaatc
    10741 ccagtcgatc catcaaagga caaccattgg atcgccttgg caaaaaaata aaccaattgc
    10801 tcccagctac tagatgattg tgctgtcacc tctccacgcc cacaggctac tagtagcaag
    10861 acaagcggca ctagggctgc tgttttaact ctttttttca atctcaaaac cttcctcaag
    10921 caattttgct agctttaaaa catgatgtaa attttgtttg actgcttgat aatctaattc
    10981 ctctgcacct ctcctagcaa taacaacgaa atcctcagac ttgaggtgat cacccagctc
    11041 cattaaaaca tgtcgtatct tgcgctttac cgcatttcga gtaacagcat ttcctagctt
    11101 tttgccaaca gaaatccctg ctcgaaaatg cttgtgctcc cctttcaaat ggtaaatgac
    11161 aaattttcga tttgccatgc tctgaccaag cttaaaaatc gcctggaaat ctttctctcg
    11221 cttgacacga tagcttttct tcaaaactta actcccatat ctaaattatt accattatac
    11281 cataaaacat taaaaagcct caacccttat caatgggcct ataataagag attggaccca
    11341 ctatctaaag gatcagaaca aaaaatgctt ttagtgaatc acggtagctg tcaagtcttg
    11401 atagccttat caatcatact agcaaagaaa caaaaaaata aagcccggta aaccgagctt
    11461 tatctccgct gacttgagca tcagcaaata tgatatccaa acaaagacaa ctgaaacaat
    11521 cattttaata acaagcagcc atatcaaaaa tactatttgt ttatggagag agagagaaaa
    11581 caatattttg attgaattgg ggatggacca ctccattacc taatgatttc gtaaatcttt
    11641 attcatacta gacattatag cgaaaaatca ctaaaaaaga tgacaatttc ctgaaatgtt
    11701 catttttcgt cctaaaatgt cattcaactt aatttttagc gaaaagactt ccacttttca
    11761 aaaagctgtt tcattctcaa acgagagacc atacaagaat caccattttc aaaatacacc
    11821 aattgcttag ccttatcaat tcgaacaaca ttgtcaagat tgaccaagta agaacggtgg
    11881 cataaaaaca gcttaggagc taccgcatga atctcagata agttcccata aaattctaag
    11941 cgctctgttt gcgtccacag gcacaccttg tgaggcgttg ttgcagttgc aaaataaaga
    12001 atgtccttat aaggcagctt taggcgggtc tgcggggtct caaacaaaaa catctcttct
    12061 acttgacgac tcgacatcat ctcataggtg tagcgaatac attcctcaat gcgctcttta
    12121 aattgctgac tatcaaccgc tttatcaata aaatccaagg cagacacctt gtacctaaag
    12181 gaaatagggg cgaactctga atgcgtcgtg acaaaaacaa gcacagcatt gggatccttc
    12241 tggcgaatat ctgaggctag ctctagccca cttcttgatt tgtcaccaat ttcaatatct
    12301 aaaaaataca gctgatgatc tcctctctcc tgaatgctat caaacagctt ttgaggattt
    12361 gaaaacacct ctaattgatt atgaggaatc ctaccctctt ctaatatgga cgccacaatg
    12421 gcctcaatac gactttgttg aatcagattg tcttccagaa taaaaatgtt tagcatggct
    12481 tatctcattt ctaacaattg tctcaaacgg tagtgatcac ttttggttga aaaggtgatg
    12541 tggggatagc gctctaacac agccgagaac tgtagcaggc gcttatgagc atggcttcct
    12601 agctccaatc ggctagcatc aaattgcttg gcaatatcaa cccgcttgag ccttgtacta
    12661 ttttcaatga taaaaaatcg cttgccatct tgattaaaat aggcaatgga taaaaaagga
    12721 cgagagctgc ctttagctga caaaatagca ttatcaataa ctaccttgaa aagaacgatg
    12781 acatctaaca gcctgacaga agagctagca agcgtttcag gaatatcgat gtaaacagca
    12841 atgccctgca gctttgcttc taatagcttg gcatgcaata ggctgcgaat caccgaatcc
    12901 tgaacattat caagggctga taattcaggt gttagctgcc tgatagagct tgctgattct
    12961 tggataactg tttgatagac cttagaaata gcagctatat ctccactatc aatactatcc
    13021 tttagactaa ttagaatatt ttctgaatca tgcttaatag ccctgatctc acgacaaagc
    13081 cgctcaatat actgattgtg cttttcaagg taagcaacac gctccttttg tgccagagcc
    13141 aatctttgag atagctgatc cttagcaaag cggtccagct tgacaatgac ccagatgagc
    13201 agcatgaggt aaagaaaaat catgacagag cggtaacgaa aataaatctt gaaaaaatct
    13261 ccttggatat tgatcatgca gtgaaccatc acatagtaga aaagtaaggc tgcattcatc
    13321 caaaagaccc acttctttag cttgtcctca ctgataaact taatcaaggt caaatcaacg
    13381 ctaaaaatat agctaaacag gtaaaaggcc ggcaaaacca atgcatgaca gaccatcaat
    13441 agacctatgt cattattgat ttgatgaatg ctgtagccta aaaccgctgg caaaaggaaa
    13501 gagccaataa tacgaaagag cagctcaaca atcataatcg caaacaagcc attaaacaga
    13561 tgctcagaag cctttttatg aggtgcaaag ccaacactga cagcaacaaa caccagctga
    13621 tcaactagca gcacatgatc cagcagcaga ttagcaacaa caaagcaggt accaaccaaa
    13681 agcaatgatc taacagctag cttaatgcct gaaaatgtcg aaaagatgac ccagctattc
    13741 acaaagatca gagcataaaa gaatgacata cctagcataa aataaaactc tactctttct
    13801 ctatttttgg catgattagg gtctgactaa actgataatc atgactcctg gtgcgcaagg
    13861 atagctcagg atatttctgc aaaatccgct tggcattaga caagcctatc cctcgaccgc
    13921 tcccctttga ggaatagccc tcttcaaaaa tcctactaat catgaccctt tcgtccttgg
    13981 tcgtattggt tacggtgaaa atctgctgat catcagataa aaagtaggct atcgccactg
    14041 ctggctgggc tgtctctaga gcagcctcaa tagcattgtc acaaaaaata gatacaagca
    14101 gcaataaatc aagctctgag atatagctat cccgaatccg atctggaact tctaggctta
    14161 aggcgattcc tgccttctca gccttaatga tttttgatga tagcaagctt tttatcgagg
    14221 atacactgat tttactgagc tttgaaatat tgtaatgctt atcgtcccaa taatccgtcg
    14281 cctcatctac cgtttgggca tagacagtct gtacatctga cacagagcca gagtcaatag
    14341 cctgccccag cctttctagc ctcttgaggt aaactagctg aaatacctta acacccttat
    14401 aaagcttttc tagatgcttt ccataggttt ccagattagc aatataagcc tgctgttcct
    14461 tttttaattc ctgttttaag aattcctttg attgatgatt aaaataagac agtaaataaa
    14521 tcaacaatag ggtaaagatg agaaacagca ccttataaga cgttgacatc attatcgggg
    14581 atttaaggtc aagaaaggga tcagtaaatc ctaaaatcat aaagagatca atatagtagg
    14641 ccaaactaaa gagcaaaaac aagctataaa agctactggc cttatcaaac ctgtcagctt
    14701 taacaatctg cttgtaatcc tttcccacaa aataattaat caaagcaaag cttgggaaaa
    14761 tcatcacata agcaataaag tctaggacaa ggtgtctgac atagctgcca ttaactgaaa
    14821 aaatataggg aagtacaatc gctaaaataa agcgtgataa caaatcaaca aacactccgg
    14881 gaacaaaggc caagaataga gcctttaagc taaagcaggg ccgcttttct aaggctaata
    14941 cagctagcag caataaagga tcaattatca agggcggcaa taaagcaaac tgattcaaaa
    15001 agagagctgc tgtcaggaca aaaatctgct tccaaagtgc cagtttaatg tctgataaaa
    15061 aggaaaaaat actaatttct gtcacataat aaatcatcag tgatagtaat aaaaagagat
    15121 aataaatatc agtcattctg cctccttacc aactttatta ttttaacaca ctttgtgtca
    15181 atccctatta tatgaatttt ttatataatt cagcaagcgc aaaaacagtc catagctggt
    15241 ttgtgacagc gtttgcaaat cagatgtcaa tcattaaagc aaattaaaat atctgaccag
    15301 ccttacctta tctagggaaa aatattgtat aacaaataat ctaagaaaac cagtgacaat
    15361 ttaatattta ttttaataat atcttccacg ctcatcaaaa attaagcaga taagcctgct
    15421 ggattatgac atctagctat gcgctactgg gcgtcgtgtc gctagctcaa gcacactaaa
    15481 aaagaatgaa gcaaacatca gatatctcat ctctgcttca ttcatgatgt tatttatgat
    15541 catcgtccag cctagaccaa actactagct gcgatagtgt ttaaagcata ttggcaatat
    15601 gctcaatcga ttgttcacgt ccaaggaggt aaatggtatt tggcagctct gggccatgca
    15661 tttctccaga aacagcaata cgaattggca taaagaggtt cttgccctta atgccggttt
    15721 ctttttggac agccttgatt tgtgggaaaa tgttttctgg cttaaagtcc tcatctgaca
    15781 tcgcctctag cttttccttg aaggccttca gaactgttgg aacagtctca gctgccatca
    15841 cttctttttc ttttgcggtc agctctggga aatctgagaa aaataaatca gtcaatggaa
    15901 caatctcatc agcagagctt aattgaggct gatagagctc aactagcttc tctgcttttt
    15961 cagtcaagcg gcctgctgct tcaagaaatg gcttacaaag cgcatataca gcgccaagat
    16021 cagcatgctt aaagtactca ttgctcatcc agtccatttt tttctgatca aaggctgctg
    16081 gcgacttgct aagacgaatc tcatcaaata aggcaatcaa ttgctcacga gaaaagatct
    16141 cagcctcccc gccaggattc cagcctaaaa gggcaataaa attaaagact gcctctggca
    16201 tatagccttt tttgcggtaa tcctcaataa actgcagggt attggtatca cgctttgata
    16261 gctttttacc tgtctcagaa ttaatgataa gggtcatatg accaaagacg ggtgcttccc
    16321 agccaagcgc ctcgtaaacc atcaactgct ttggcgtatt ggcaatatgg tcatctccgc
    16381 ggataacgtg tgagatttgc atatcgtgat catcaataac aacagcaaaa ttgtaggttg
    16441 gatagccgtc ttttttctgg attacccagt caccaccgac attgccaccc tcaaatacga
    16501 tatcgccttt taccatgtct gtccatttgt aaacaccagc ctcattgacc gctaaacgaa
    16561 ccgtaggcac aatacctgct gcttcacgct ctgcaatata ggccgccttt tcatatgctg
    16621 acatgccaag gtattcattg acatagcgag gtgtttcacc agctgcctct tgacgctcac
    16681 gctctgctgc cagctcctcc tcagtcacat aagacttgta agccttgcct tctgccaata
    16741 attggtcaat gtattgttga taaagggcta gacgctctga ctgacgataa cgctcgtgcg
    16801 tctcaggact ttcgtcccaa tctataccaa gccattttaa attttccagc tgagaacgct
    16861 cgccgtcctc gacatgacgc ttacgatcag tatcttcaat acgaataata aagtcaccgc
    16921 catgatgacg agcataaaga tagttaaaga gcgctgtccg cgcatttccg atatgtaaaa
    16981 ggcctgttgg gcttggtgca tagcgcacac gaattggttt agacattctt tttctcctat
    17041 ggtttcattg aaagaaggga tcctgggcta taaaccgttc ctacggtagg cttgctctat
    17101 gagaaaatgg tcgataagga acaaaaatac agctaatccc ttggaaatct aaagatttca
    17161 atcgctccta ttatagcaca acttcaagca ttgggcgaca aaaatcaact tagaacagct
    17221 gcataacgaa aatgcatgta accattttct agctacatgc attgttttca tctacttctg
    17281 atattttgat atcatcagct gttcacattc agcttaattg tagcctgaat tgatttgaaa
    17341 aagaccatac cactgatgag aaaatcgcta tcaaaaacgt aaagatcctt atgcgtttgg
    17401 cgtggcctag agctaggata gctctataag cagctcattg gcaagcagtg ctgcctcttt
    17461 caatagcttc atagcatgcc tagctataga tattagtcag gctattgacc tgcattgatg
    17521 tcaagctaca ccccagcaaa gaaagcgaca atatactctg gcaaccacga acctgtcata
    17581 tccatttcaa tccatcaatt ggcaaggctt ggtttacttc caactgctta atggccgcct
    17641 gtgacaatat agctctgtaa aactccagca aattgctgaa ggttcaggct ttgcacatag
    17701 acatctccgt atccgctaaa ggtattgacc actccctcac ctgtaccaat agactgcata
    17761 aagccatttt ccaaatgaat atcataatcc aaatcctgac tccaagccac cacatggcta
    17821 ttatcaatcg tcatgctgtc gccatgaagc gtgatttttt taatcgaacc aaaagcattg
    17881 accaataggg ttccttctcc ttgtgttgac atcacaaaga agccaccctg accgctaaat
    17941 aaggccttac caagtttttg gcgcttcatg gtgtagtgag ctgagccatc taaagccaag
    18001 aaggctccgt cattcaaacg gtattgatct acccctagct caagagcaat aacctgacca
    18061 ggcattgaag gggcaagcgc tagcttgcca ctaacatcat tagcaatcgc ctgtgtgata
    18121 aacatggatt ctcctgaaac cattgaacgg ccaatggcac caaccagctt gccaagacct
    18181 gagccacgcc cattgagctt ggtgtttaag ctgattgacg gtgtgtggta aaccatactg
    18241 cctttttgta gaaagacaga ctcccccatg tccaaatcaa tttcaacaag aggaaactgc
    18301 atgctgctgt caatagtata ggtcattcga ttataggcca taacaccact cctttgtatg
    18361 attttgttga tacaatcaag tatagtcttt tttggcagca ttgtccacta gctactgtcg
    18421 ccgccattcc taaccagtct caaagccata ctacaaaccg atcagctgtc aggatttcgg
    18481 catcgccacc tgagacatac gtccagtggc aacatcatag accgcaccac taatgaccac
    18541 gtcttttgga atcaacggtg attgctgcaa tatagccata tcctcacgaa cacttgcttc
    18601 cacatcagta aaggggagaa aatcacagtc agacacatct actcccagag tatcatgaag
    18661 ctgcgctgta aaggcttcat tggtaaaggt ttgcgcccca caatccgtat gatgaagaac
    18721 aacgatctca cgcgttccca gctgctgctg cgaaatcaca agagaccgaa gcatgtcatc
    18781 tgttatccgt ccaccagcat tgcgtaaaat atgggcatca ccaagcgcta aacccaaggc
    18841 ctgcgccaca tgcagtcttg agtccataca ggtcacaata gctaccttag ttttgggctt
    18901 taggggcaaa tgagcagtcc catgtaaggc gacataggct tcattggcag ataaaaagcg
    18961 ttcaaaatat gacatgaata cggtcctccc agactaatct ctaagctatc tcagccttga
    19021 gctgtctgtc tatcttatca tcttttgcct gaaatgtctg aatgctgaac tgctttttaa
    19081 cacaagcaga tagcactagc ctaactgaaa ccagaggtag gtgagccagc cttgacattg
    19141 gaagcaagct tagcagcccg ccctttgagc cgctaaagta agggcagcaa gaacgtgaca
    19201 aaatcagtta attgtcattt taattaaaaa acgaaactac ggagacaaac tgataaattg
    19261 ctatttctcg ctatcagcca gtatgctaaa ctcttctcag aaggccttgg cagtcgctag
    19321 ctgctaagcc aataatacta aattaaggag aatagcaatg aaacaaacaa aaataatctg
    19381 cttattggct gctgctgctg tcctaaccct aggtcctatc agcacaggcc agacacaacc
    19441 acagaccgta tatgccagtc aggttagtgg agacagctgt atcgatctag gtaatggatg
    19501 gtttaaatgt cctaaggata ttggaggatg ggacattctt tttaatcaag attaccaagc
    19561 gccttcacga tcgccatttt tcacttggat ttcaggctgg tttaacttta tatggcagtg
    19621 gtttaaaagc ttctaagatc tactaatacg ctatccatat cataaggctc ttagaggcta
    19681 gctctctaag ggctttttgg ttctacggaa cactataagg accttccaat actactggtc
    19741 ttaaaataaa aaagactagg aatagctccc ctagtcctca tgttaaaaac aacaacctaa
    19801 gtaaagacag cctttaagac ctctcctact gtcgtcacac caacaacctc aatccctttt
    19861 ggcagatcaa tcccctgcaa tgagcttttc ggagcgtaaa gcttggtaaa gccaagctta
    19921 gcggcttcat taatccgctg ctcaatacgg gtcacacgcc gaatatcacc agtcaagcca
    19981 atctctccta aaaaggcctc ctgagggttg gttggttttt ccttgtagct agaggcaatg
    20041 gccacagcaa ctgccaagtc aatagcaggc tcatctagct tcacaccgcc tgctgacttg
    20101 aggtaggcat cttgattttg tagcagcagc ccacatcgct tttccaagac agccataatc
    20161 agactgacgc gattaaagtc caacccagtt gtcgttcgtc tagcattacc aaaaacagtc
    20221 ggtgtcacca aggcctgcac ctcagctaaa atcggtctgc tcccctccat ggtgacaacc
    20281 acagcagagc ctgttgcgcc gtctaatcgt tcctctaaga acacctgact gggattgagg
    20341 acctccacta gcccacctga ttgcatgtca aaaataccaa tctcattggt tgagccaaaa
    20401 cgatttttaa ccgctcgcaa gatacgaaag gtatgatgcc tctcaccctc aaaataaagg
    20461 accgtatcaa ccatatgctc cagcatgcga ggccctgcta gggtgccctc cttggtgaca
    20521 tgtcctacaa taaaggttgc aatatgatta gacttagcta gctggagcag ctcagcagtg
    20581 acctctcgaa cctgactgac cgagccctga acacccgaaa tctccggact catgatcgtc
    20641 tgaatagaat caataatcaa aaaatccggc tgaatggctt caatctctgc tcgaatagcc
    20701 tgcatattgg tctccgcata gaggtaaaaa tcattgtcgg tctgtcccaa acgatcactg
    20761 cgcatcttga tctgctctgc cgattcctct ccagagacat ataaaacagt tcccttatcc
    20821 gcaagctgga tagaaacctg caagagcagc gttgacttac caataccagg atcaccacca
    20881 atcaaaacca agctccccgg cacaacacca ccgcccagca cacgattgaa ctcattcatc
    20941 tctgtctgga tacgctggta gcgaacgcca ttgatatgct ttagcttgat gggcttactt
    21001 ttttctccag tcaggctaat acgggcattt ttgacgtcct tgacctctgt ctcctctaca
    21061 aaggaagacc aggcagagca attagggcag cgccccagat atttgggtga ctgatagcca
    21121 cattctccac agataaacct cgcctttttc ttagctataa cacatttcct ccttgaatct
    21181 aagcatcaac tggctacaag cacgtgaagc agcctgctaa taccttatcc tcctgtcgaa
    21241 ccaaaaccac ctgtccgctc accaccagcc tgatcaccat cagcaatcaa aaaaggcata
    21301 aatacgccct gaacaatgcg ctcaccagct gacaaggtaa tggtttgatc cgtaatattt
    21361 ttcatctgag caaaaatatg cccttcattc gcagggttac catagtagtc accatcaata
    21421 acacccacag aattgatcag aaccagtccc tttttacgag gattgctgga gcgatcatag
    21481 agataaagca cctcaccgtc ttgcatatac gccttgaccc ctgttggcac aagtacaatc
    21541 tcacctggtg caatgctggt ctcctctgca acagataagt catagcctgc tgcatgagct
    21601 gtctcacgtt ttggtaataa atcagtatca gtaaagcctg acacaagctc aaagcctcga
    21661 atccttgtca tgattaacct caagagccct tgtcagtgcc tgcagcagct gtaaaatcac
    21721 ctgccaggac agcagacaaa agcactctta tcccttttct ttttttagtc ctcttattat
    21781 aaaatattcg taaaggaata gcaaaaaagt aggggctgca ccccaaaaat caccgactgc
    21841 ccccctctat aacgcaacaa aatgcaagag ggctaaatct ccttgccggc atagctaaac
    21901 cgaatccttg gaaaatcagc ctccaaatcc ttatctgcca taaaagcctt ggcgtccttt
    21961 ttcacctgaa ccagatcaat cccttgtatg tttgcagcat agacgcagcc gcaatagcac
    22021 tggcggtaaa tatcatattc ctcacacatt tcgaccgacc tgcgatagcc attatttttc
    22081 ttgaaatcac taggcaaata cttagtggtg taaacctttt gcacatcaat gcctacatcg
    22141 ttaatcgtct gtgagttttt atgagggctg atggtcaagg cactagcaaa ataatcaaag
    22201 cccagctcca cagccttttg tgccgtcttg tccaagcgat aatcaaagca aacacgacaa
    22261 cgatccccgc cctcagactc tttctccaag cctcggacag tcttgacaaa ttcatttggc
    22321 acataatctg cctcgataaa ctgcacgcta ttacctgttt tatcgttgaa ctctgctaca
    22381 aatttctgag taacataggc cctgcggtgg tattcgtcct ttgggtgaat atttgaatta
    22441 gcaaaataaa ccgtaatatc agcgtactgg gttaaatatt ccagcgtgta ggttgagcag
    22501 ggagcacagc aaacatgcat caaaatgcga ggacgtatag actccctcgc ccagaccttg
    22561 gtcatctgct gcatgacccg atcatagttt attttctggt ttggattcat tctagctaga
    22621 atctcttgta agtcaatcat tacatcttct accttctatt gtctgtctct tttattatag
    22681 cacattgcct tgacatgctt tgcatcaaaa aactccgcca aagcggagtc gatcggcaaa
    22741 agctgttttg atggttttta agaataacaa cagcagctta tgtaatgatc atttttagaa
    22801 gctactcaaa cacaaactga ttgtgataaa gctcggcata aaagcccttt tgccttagca
    22861 gctcatggtg acttccctgc tcaataacct taccgtcctt tagaacgatg atttcatcag
    22921 catttaaaat ggtttttagg cggtgggcaa tcacgaagct tgtgcgacct gccacgatag
    22981 cctccatagc cttttgaatc ttactttcag taacagtatc aacatttgat gttgcctcgt
    23041 ccaaaatcaa gacctgagga tcggttaaca gcgtacgagc aattgaaata agctgctttt
    23101 gaccagttga aaagacattc tcatcatctg acacctgagt ttggtagcca tcaggcaagg
    23161 acatgataaa ctcatgaata tgcgttgcac gcgctgctgt ctcaacctct ttttggctga
    23221 ttgtctgatt accaaagcgg atattatcag caatagtccc agaaaacaag actgactcct
    23281 gtaggacaat accaacccgc tgacgcagac tatccaagtc atattcccta atatcacgac
    23341 catcaaaggt aatagagcca gcatcaacat cataaaaacg attaatcaga ttcatgatcg
    23401 tggtcttgcc agaccctgtc ggtccaacaa cagcaaccat tttccccttt ggagctgaaa
    23461 tcgacacatc tgacagaatt ttttgtcccg gcagataacc aaagtcaaca tgcttaatct
    23521 caaccccttc ttttaatgct gtaaagacag gagcatgctc agggcgaacc tcttcttttt
    23581 catcgaacat ttcttggata cgaccagcac ctgtaaaggc cagctgcaat tcaccccagc
    23641 tagaggcaat ctgcataatc ggttgataat actgctgtga atactgaaca aaggtcacca
    23701 ccaagccaag agcagcagct gttgacatgg acttgtcacc aaggacaatg gttgagccag
    23761 caaagatgac aatagctgta ttcaaaagac tcatcccatt catcacagga aacagcagac
    23821 cagcaaaaag gcgtccctta aaggttgctg cacgcaccct ctcattgtgc tcaataaagc
    23881 catcaatagc atcctgttgc accccttgaa caataatagc cttctggcca gaaatcttct
    23941 cgtccatgta agcatttaaa gcactgacct ccttttgctg caaatcagta tatttgcggg
    24001 ccattgtaat gatgacaacg agaagaataa gcgccacagg ggttgaggct atcgttacca
    24061 aggccaagcg actatcctgc ctaaacatca tcagcactag accaatatac aaagcaatat
    24121 ttgtcaagac ctgaatcaga gattggttca tggagttttg aatattatca agatcactgg
    24181 taaagcgtga tagaatagca ccgtccttgt gactatcaaa aaagccaact gtcaagcgct
    24241 ccaatttgcc aaataagccc ttacgcatgc gattggtcga atgcgaaata acccttgtaa
    24301 agaggagact ataaataaga ttagccactg ctgtaaagag ataagccaac aatagctttc
    24361 ccataaccgt cctaaaaggc gccatagagg gctcaactaa gggctgaccc gtcattttgc
    24421 taagcgcctg agccttgtaa tagcgctgca cccattctcc cagctcagct agagagtctc
    24481 ccaaaaagac aggggcctta acctgcaggt aggttgccag gacaatagca aagaatatca
    24541 caacaaaaga gagcttataa cgtttaaaat aaaaccagaa aaatcgcagg atcttcatta
    24601 gttctcctct cttccctttt gagtttcgta aatttcacga taaatcggat tggaagcaac
    24661 cagctcagca tgcgtccctt ctccaatcaa tcgaccatta tcaagaacaa gaatcttatc
    24721 tgccttgaca actgacgata ttttttgtgc gatgatgact gttgttgtct ctttgagctc
    24781 cttattcaag gcctcctgaa caagcttttc agatttggca tctagagctg atgtcgaatc
    24841 atcaagcacc aaaatcttag gattgttaat cacaccacga gcaattgaca ttctctgctt
    24901 ttgaccgcca gaaaaattat tgccacgctc ttctacctca ctctggtagc cagcgtccat
    24961 acggtcgata aattccttgg cctgcgcaat gcgtgctgca ttttctaaag ccaattggtc
    25021 agcataggga ttgccctgac gcagattatc cgcaatagtc ccagaaaaaa gaatagcctt
    25081 ttgcagcaca atagagacgg tgtcgcgcag agtctcttga ctgatgcttg gcagagcctt
    25141 accaccaatc aggatttgcc cttcctgtgg gtcaaacaaa cgcggaatca gctgcgcaag
    25201 ggtcgacttg ccagcacctg tcgcaccgac aataccaacc atttgaccgg gctcaacctc
    25261 aaacgaaata tgctttagag tggcttcact gtcatttgga taggtaaagc tcacatcatc
    25321 aaagacaata ctgcctgtca gctcctcctg ctcatggtta acaaaggtca tagcaggctc
    25381 tgtttctaaa atctccctga tccgaccaat cgaggtcaag gcacgacttg cctgcattcc
    25441 cataaaacca accatcgtga tcgcaaagct gatttgtccc atataggtca taaaggaagc
    25501 catatttcca ataacagcag gatctgtttt gaccagccct gaaaccagat acaaggacaa
    25561 ataaatggcc atgtaagaca ccaacatcaa aataggctgc atgattgaaa agccatagcc
    25621 gataaacaaa ttcaagccca gtaggtcatt tgaagcctcc ttaaatgtgt catactggct
    25681 tttttcctga acaaaggact tgaccacacg cacaccgcgt aggttttcct tagcaatctg
    25741 attgatccta tccatcaagc gctggaagat cccaaagcga ggacccatct ggctcatcac
    25801 cagcccaatg actaccattg tcatcacaac cacaagcacc aagacccacc aaaggctcgg
    25861 taaggcctgc accgctaaaa taaaggcacc gacaaataaa atcggcaagc gcaacaatat
    25921 ctgaaaaagc atcatcacaa agttttggat ttgattaata tcatttgtca ttctaacgac
    25981 aagatttcca gcattgaagg cttccacatt ggcataagaa aaggattgga tctttctaaa
    26041 ggtctgctca cgaatatcag cagatacccc ttgagcaatc ttggcagaca agatggtatt
    26101 gaccgcacct gacaccaagc caatccctgc tatcactaac agccaaaaac ccacctctgc
    26161 aatccttgtc tgatcatttt ccataatagc agctagaaca tctttgaggt aatgtggctg
    26221 gagcagggca ctggctacga ccccagaaat catcactagg gacagagccg cataccattt
    26281 atacttcatc acagcatttc taagcatctg tatctccttt ataagctcgt atattttgtt
    26341 tcagctgatc gataaccttt tttaccgtca gcagctcttc tcttgaaatt tccttgaaaa
    26401 aatagcgctc aatatctctg cggcactcct ttaataccgg cagcttagcc ctaccagccg
    26461 aggtcaagac aacctgcttg cagcgcttat ctgtagccga ggcaacaact cgaataaagc
    26521 catttttttc catacgcttc accagattac tcgtaaccga ttttgagatt tgaagctcct
    26581 tttcaatgtc cttgacaaaa atgtctctgt cttgatggca atgcaaaaag acaagaacat
    26641 gcccttgtgg accagcaaga tgctggaggt catacttttt agcaatctct tcgctaattt
    26701 gctcaacctg atgggtcaat tcacgaagct cagcaatgat tcttggcatt tccttcctcc
    26761 ttagttctca tgataaccat tttagttctc ttgggaacta ttgtcaacca aaaaggctta
    26821 cgatctgact atcttccctg ctacttaccc tttgctagca ccactgagct gacaggctag
    26881 gccagcagac cttttctatt agagttaggc cttgtcttat gatataataa ggtgattagc
    26941 tcttaaagga gaataaaaat gccaaaacaa aaggtagcca ttttgggacc tggctcttgg
    27001 ggcacagccc tggcacaggt cctaaatgac aacggacatg aggtccgact atggggaaat
    27061 atccctgaac aaatcaacga aatcaacaca cgccatacta atagtcatta ttttaaggac
    27121 attgtcctag atgaagccat caaggcaacc cttgatttga aggaagcatt ggctgatatt
    27181 gatgctatat tgtttgttgt gcctaccaag gtgactcggc ttgttgccaa gcaggtcgct
    27241 caggtcctag accacaaggc tattgtcatg cacgcctcaa agggattaga gcctggaacc
    27301 catgagcgcc tctcaacgat cctcgaagag gagatccctg cccagctgcg cagtgaggtc
    27361 gtggttgtgt ctgggcctag ccatgccgag gagaccatcg ttcgtgacat taccctaatc
    27421 actgcagcct caaaggacat cacagctgct aggtatgttc agaccctctt tagcaaccac
    27481 tacttccgtc tctacaccaa tactgatgtg atcggtgttg aaaccgctgg cgctctcaag
    27541 aacatcattg ctgttggagc cggtgctctg catggccttg gctatggtga caatgccaag
    27601 gctgctgtca tcacacgcgg tcttgcggaa atcacacgac taggggtcaa gcttggggca
    27661 gaccctctga cctatagcgg cctatctggt gttggtgatt tgattgtcac aggaacatct
    27721 gtgcattcac gcaactggcg agctggtgct gctcttggtc gcggcgaaaa gctcaaggac
    27781 atcgaaaaca atatgggcat ggtgattgaa ggcatttcca caaccaaggt agcctacgaa
    27841 attgcccaag agctaggggt ttatatgcca attaccagcg cgatttacaa atctatctat
    27901 gaaggtgctg acattaaaga aagcattctg ggcatgatgt caaatgaatt tcgctcagaa
    27961 aatgaatggc acacataagg aaccacaaat caaggaggaa ctcatgacaa aggtcagaaa
    28021 agccattatc cca
//
LOCUS       DARYMD010000029        25751 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYMD010000029 DARYMD010000000
VERSION     DARYMD010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25751
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(18..455)
                     /locus_tag="TU818_001179"
     CDS             complement(18..455)
                     /locus_tag="TU818_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL0924000.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYFVFRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYYIFKQHRSR"
     gene            656..1348
                     /locus_tag="TU818_001180"
     CDS             656..1348
                     /locus_tag="TU818_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0924001.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQKEKIIALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQDSFDYDGAIYAVEWEEQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
     gene            complement(1724..2200)
                     /locus_tag="TU818_001181"
                     /pseudo
     CDS             complement(1724..2200)
                     /locus_tag="TU818_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515631.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2413..3975)
                     /gene="guaA"
                     /locus_tag="TU818_001182"
     CDS             complement(2413..3975)
                     /gene="guaA"
                     /locus_tag="TU818_001182"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL0924002.1"
                     /translation="MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4262..4960
                     /locus_tag="TU818_001183"
     CDS             4262..4960
                     /locus_tag="TU818_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0924003.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLENN"
     gene            5172..5504
                     /locus_tag="TU818_001184"
     CDS             5172..5504
                     /locus_tag="TU818_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL0924004.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            5519..7090
                     /gene="ffh"
                     /locus_tag="TU818_001185"
     CDS             5519..7090
                     /gene="ffh"
                     /locus_tag="TU818_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL0924005.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(7243..8466)
                     /locus_tag="TU818_001186"
     CDS             complement(7243..8466)
                     /locus_tag="TU818_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL0924006.1"
                     /translation="MINVAFNSKIGISAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQN
                     ERIGIFQGDNQVASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKK
                     KRALLIKFDPMILLKQHQLGEKAPDNSKALTIIKHLKRFGAHWTGPTTKLSDTIQPRF
                     QANCYTNADIEASFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVAL
                     RNEAYFRQLMTTYGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARL
                     TDQKQSLQRYLSEFKDFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYL
                     LYPKVFMDAYHDDIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHL
                     ANLLYKIRKQLKHRH"
     gene            complement(8691..9662)
                     /locus_tag="TU818_001187"
     CDS             complement(8691..9662)
                     /locus_tag="TU818_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL0924007.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEENKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDSLMGN"
     gene            complement(9975..10415)
                     /locus_tag="TU818_001188"
     CDS             complement(9975..10415)
                     /locus_tag="TU818_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0924008.1"
                     /translation="MTKKAYLSLFTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(10412..11347)
                     /locus_tag="TU818_001189"
     CDS             complement(10412..11347)
                     /locus_tag="TU818_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL0924009.1"
                     /translation="MIRGFKKTIVAVGLLAVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAQNTSIHSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHFTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     DLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKMNLETLYRVLESET"
     gene            complement(11785..12198)
                     /locus_tag="TU818_001190"
     CDS             complement(11785..12198)
                     /locus_tag="TU818_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL0924010.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPDRHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDKEACGLRHLAFHVKPIEAYIEQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(12296..13051)
                     /locus_tag="TU818_001191"
     CDS             complement(12296..13051)
                     /locus_tag="TU818_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL0924011.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDDVLKAFNHSYNQMST"
     gene            complement(13056..15551)
                     /gene="gyrA"
                     /locus_tag="TU818_001192"
     CDS             complement(13056..15551)
                     /gene="gyrA"
                     /locus_tag="TU818_001192"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL0924012.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILARPERIEAIIKEEMEEIKRKYANPRRTELMIGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAIAQTDTALTEAPINSSKE"
     gene            15743..16726
                     /locus_tag="TU818_001193"
     CDS             15743..16726
                     /locus_tag="TU818_001193"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL0924013.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKTIIDEAFSKEEFASAAKN"
     gene            complement(16931..18298)
                     /locus_tag="TU818_001194"
     CDS             complement(16931..18298)
                     /locus_tag="TU818_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL0924014.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYGVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(18548..19150)
                     /locus_tag="TU818_001195"
     CDS             complement(18548..19150)
                     /locus_tag="TU818_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL0924015.1"
                     /translation="MFRVLKRILGLAVLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEADVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHTIELATNYSRTVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(19151..20128)
                     /locus_tag="TU818_001196"
     CDS             complement(19151..20128)
                     /locus_tag="TU818_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL0924016.1"
                     /translation="MLDIYIKGIVIHQFTPNDTELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTIGTELLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     EGVPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(20131..21390)
                     /locus_tag="TU818_001197"
     CDS             complement(20131..21390)
                     /locus_tag="TU818_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL0924017.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETEKLDYAAIL
                     KQAKAVQPKLIVAGASAYSRQIDFEQFRFIADQVGSYLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAISRKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HQQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(21402..21833)
                     /locus_tag="TU818_001198"
     CDS             complement(21402..21833)
                     /locus_tag="TU818_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0924018.1"
                     /translation="MLRPLDQTDCQAICDINDQSLGYKVSLELTKSQLEKLRSDKHHY
                     LLGYADTKTNLLLGYLHAECYESLYSEKGFNILALAVRLDHQGRGIGRRLLAALEEKA
                     KQEKVSFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(21847..22440)
                     /locus_tag="TU818_001199"
     CDS             complement(21847..22440)
                     /locus_tag="TU818_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL0924019.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAQTPYWINSGLK
                     TVGFRLPSHPLTAKIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKVDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(22412..23260)
                     /gene="prmC"
                     /locus_tag="TU818_001200"
     CDS             complement(22412..23260)
                     /gene="prmC"
                     /locus_tag="TU818_001200"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL0924020.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEQSDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFSIYRR
                     IIEQASAYLTTSGKLYFEIGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(23257..24339)
                     /gene="prfA"
                     /locus_tag="TU818_001201"
     CDS             complement(23257..24339)
                     /gene="prfA"
                     /locus_tag="TU818_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL0924021.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(24381..24950)
                     /locus_tag="TU818_001202"
     CDS             complement(24381..24950)
                     /locus_tag="TU818_001202"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL0924022.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            25137..25322
                     /locus_tag="TU818_001203"
     CDS             25137..25322
                     /locus_tag="TU818_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL0924023.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            25377..>25751
                     /locus_tag="TU818_001204"
     CDS             25377..>25751
                     /locus_tag="TU818_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL0924024.1"
                     /translation="MIATDQIKMMGTIIDICIDSSKAKQQAATIRELLTLYNHRFSAS
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHII"
BASE COUNT         7549 a         5408 c         4870 g         7924 t
ORIGIN      
        1 gctaagctaa ggctgtttta tctgctacga tgctgcttaa aaatatagta tttactaaca
       61 ataaaattca agctaatcat tatggcttgg ctcaaaatgc tttcaacaga attaatgctt
      121 tcagaatcat gttcaacaag gcttccaatg acctctgggt atttttcgac taataaatag
      181 gctaatagca tatctaagcc taatgttact actctagcta ggaaaaacat ggcaaatcta
      241 aacaagcgtt tttcagaagt ttgcttaaaa acatagctat cgttcatcaa gaaggcagct
      301 atgatcgcta taatattggc aaagcctgct gatatggtgg cctgatgtaa ccatgaatag
      361 atgacatacc gaaaaacaaa ataaagaatg gttgttagaa gaccagatat caggtaatga
      421 ctgatttcaa gtgataattt ttgtttgcta agcatttttc tttcctatgt gtatttatct
      481 tgactgttat attttgatgg atctatataa gtataacatg tttggcatta aacctaagac
      541 agcttactgt cttttcgata taaacataaa aagcttgaat attcttataa gctatgttat
      601 actctggtaa agttaatact ttactagagt atactgacaa aggagattta tgctgatgtt
      661 ttctggtatt caattaaaaa cagcacgttt atcaaggcat attagccaag aacagctagg
      721 acagctttta ggagttaata aaatgactat ttccaattgg gaaaaggaga aaaatagacc
      781 aaatcaaaag cattttgaag agcttgtgag catttttcaa ttacctgctg agtactttta
      841 tcaagaaaat cgtcttttac ttccctatag tcagttaagc gcctctaata aagaaaaagt
      901 tatcagctat tctgagagct tacttgaaca aaaagaaaaa ataattgctt taccagctaa
      961 gaaaaagaca ctttaccctt atcgtgttta tgaaaggttg tctgcaggga ctggctattc
     1021 ttactttggt gatggtaatt ttgatgttgt cttttacgat gagcagttag attatgattt
     1081 tgcttcatgg gtttttggtg actccatgga gccaacctat ttgaatggcg aggttgttct
     1141 catcaaacag gatagctttg attatgacgg tgctatctat gctgttgagt gggaagaaca
     1201 aacctatatc aaaaaagtat atcgtgaaga aaatggtctg cgtttggttt cattgaacaa
     1261 aaaataccct gataaattcg cttcctttga tgacaatccg cgtattattg gaaaaatcat
     1321 tgccaacttt atgcccttag atgtataagc ctttgtatta gcttaaaagc atgactgttg
     1381 tacaaccaaa ctcattgcat gacattggtg cattattttt gaagtggctt ctacttcttt
     1441 gatttacttt tctgcattaa aaagcccatt aaaggttttt gaaacttatt acttagacaa
     1501 aggctctatt aaaaatcata accaaccggt ggtggtttat ttgtcatgta ccttgcattt
     1561 tgtgacagac ttcataaaac gaacaaaaca catcgctaaa agattttacc atcttaaagt
     1621 tatgtgtttt ttgtataaaa acttatctat atgcttgatt aaccaactga gataaataga
     1681 ttattatttc atagagaagt ttgttatcta atccaaataa tcgtattatc ctcttaagtt
     1741 cctcaacatt ataaccatca caatctgttg gcagtttatt tttttcaagc cacttatcaa
     1801 ccactgctat tcccaaagaa attgaaaaat ctttttcttt atcaaactta cacaattcca
     1861 ctgccaaagt caatacaaaa ttcctgtgaa tattatcgta attttcatca aataattgcc
     1921 tttccaaacc cacaatagat agccgactaa atatgtatct ccctatttct tcgtcaatac
     1981 cttcagtagc cttaatagct tcttggacaa cattattcca gaaagcattt ttattacgct
     2041 cttctataaa agttttaagt ttcattttga aaatatcagt aatttgacca actgctttat
     2101 caataaccta tgaaacaata ttcttcatca ttatgatttt ctcctcgtat acataaataa
     2161 ttgtatcttt gctatataat tgtggtatct cttcaatcaa ccaatattgt tcttaaacta
     2221 ttccctcaaa agccttccac caaaacgatg gaaggctttt aaaccattca cctaaattca
     2281 acaactccct tttgaacttg ctattttagc tttttagtat caaagcagta tcactcaaga
     2341 gttttttgtt tccacaaacc gcaaaaaccc actgttttca acactttcat ggcagtaata
     2401 tatttgcttc tgtcactccc actcaacggt tgctggtggt ttgctggtga tgtcgtagac
     2461 aatgcgatta acgtggtcga cttcattgac aattcgaact gagattttct ttagaacttc
     2521 ccaaggcaat tgggcaaagt ctgctgtcat accatcaatt gaggtgatag cacgaatagc
     2581 gatggtatag tcataggtgc gaccatctcc cataactccg acggaacgaa cacctgtgtt
     2641 aactgtaaaa tattgccaca catcacgctc aagtcctgct ttagcaattt cttctcgaag
     2701 gatagcatct gactcgcgaa cagtttcaag cttttctgct gtgatctctc ccatgacgcg
     2761 aatggcaagg cctgggcctg ggaaaggctg acgccagacg acttcatctg gcataccaag
     2821 ggccgtacca agagcacgaa cctcatcctt aaagagtgta ttgaggggtt cgattaattc
     2881 aaactgcata tcctctggca gaccaccaac attgtggtga gattttatcg tttgagcagt
     2941 ttctgttcca gattcaatga tgtctgtgta aagcgttcct tgtgcaagga agtcaacgcc
     3001 cttaagcttg ctagcctcgt catcaaagac gtaaacaaac tcattaccga taattttacg
     3061 ttttttctca ggatcctcaa cgcctgcaag aagatctaaa aagcgctttg aggcatcaac
     3121 acgaataata ttgagaccaa atcttccacc aagcatttcc ataacttggt caccttcatt
     3181 tttacgaaga agtccatggt caacaaagat acaggttaat tgatctccga tagctttttg
     3241 taaaaggaca ccaacaactg aagaatcaac accaccagac aaacctagca aaaccttacg
     3301 atctccgact gtttcgcgaa ttttagcaat ttgcatgtca ataaaattat ccattgacca
     3361 atcaccacgt ccaccacaga tagagatagc aaagttcttc aaaatatcat taccatagac
     3421 agagtgtctt acctctgggt ggaattggat accgtagagc ctcttttttg tattttccat
     3481 agcagcgtaa gggcaatcgt tagaatctcc tacaagatga aagccctctg ggatttctgt
     3541 aacagcatca ccatgactca tcaaaacaag ctgctcatct ggagtgcccg caaataatgc
     3601 tgatgcagaa cgtaaacgta atgatgattg accatattct cggtgacctg cttgaccagc
     3661 tgggactacc ttacctccta aggtatgtgt gattagctgc atgccatagc aaatccctaa
     3721 aattggaatc cctaattcaa agatttcagg atcaatacca aaggcatcag ttgcataaac
     3781 agaatttggc ccaccagaca ggacaatccc gattggattg atgtcacgaa gctcttgcgc
     3841 agtgatgtga tggcttttga gctcagaaaa aacaccaaac tcccgaatac gtcttgcaat
     3901 cagttgattg tactgactac cataatcaag aacgataatt ttttgaatat cattcaacat
     3961 tgaaatttca gtcattataa ccctttcatt atataccaga accttgttag ctgatagttt
     4021 tcaattaatt gtagcatatt ttcactaaaa aggcattagc ttttcaggtg atgtgatgaa
     4081 aaaataagct ttttgcagag atattaaaat gaatgacctc aactatctta tgtatgacta
     4141 ctattgtcag tcttagcatg aaaaagctga ttgatgatga gtgtttttgg taataattgg
     4201 gctgctattt aggctgaaaa tatgataaaa taaaaccatc atcaccctca aggagtaaag
     4261 catgctgcca gcttatataa aaattcatga cgctattaaa aaagacatcg aaaaagaagt
     4321 ttggactatt ggtagtcgcc tgccaagcga acgagattta gcagaacatt ttgaggtcag
     4381 tcgcatgacg ttgcgtcagg caataacact gcttgtagag gagggaattc tagaaaggcg
     4441 tgttggtagt ggtacttatg ttgccagcca tcgcgtacaa gagagaatgc gtgggaccac
     4501 tagctttaca gagatcgtga attctcaggg acgtaagcca tcttcaaaac tgatttccta
     4561 tcaacgtcag ctagcaagtg atacagaaat aaatcaattg cacttagaag aatcagatta
     4621 cgttattcga atggagcgca ttcgttatgc agataaggtt cccttagttt acgaggtagc
     4681 atctattcct gagaaattta ttaaaaatgt caaaaaaact gatattacag agcacttttt
     4741 ccaaacccta acctcaaacg gttatgaaat cggcaaaagt caacaaacca tttacgcgaa
     4801 aatagccagt gagcgtgtcg cctcttatct agaggtcgct aaggggcatg ctattttagc
     4861 attgactcag gtttcctttt ttacagacgg taggcccttt gaatatgtgc gtagccaata
     4921 tgtaggtgat cgctttgaat tttatttaga aaataattaa tcataagcaa tgatgtttaa
     4981 ataacattga taggaagtgg ctcaccactt ctttttttca acacttgtca agtatatcaa
     5041 tatttcaaga acagttatta aaacaagcta ctattatcct catttttgct ctaagaaagc
     5101 ttcctgataa aaggctgatc gctatcattt accactgtta aaaatgctca tgatgtgata
     5161 aaatgaagat tatggaaatt gaaaaaacaa accgaatgaa tgctcttttt gaattttatg
     5221 ctgccttatt gactgataaa cagatgaact atatcgagct ctattacgct gatgattata
     5281 gtctggctga aattgctgaa gaattcggtg tcagccgcca agcagtttat gataatatta
     5341 agcgcactga aaaaattctg gaagcctatg aaatgaagct tcatatgtat tcagattata
     5401 ttgtacgtag tgaaatattt gatgatattc ttgcaaaata tcccagtgac cactatttac
     5461 gtgacaaaat ttccatttta actagtattg acaacagaga ttaagaggag ttatagctat
     5521 ggcatttgaa agcctaaccc aacgtttaca ggacgttttt aagcacattc gtggtaaaaa
     5581 aaccttatct gaagccgatg ttcaggaagt gaccaaggag attcgtctag ccttattaga
     5641 ggcagatgtt gcacttccag ttgttaagac ctttatcaag cgtatacgtg agcgagctgt
     5701 tggccacgaa attattgata cccttgatcc aacgcaacaa atacttaaaa ttgttaatga
     5761 ggaattaact ggtatcttag gatcagaaac cgcggagctt gataaatcac ctaaaatccc
     5821 tactgtcatc atgatggtgg gcttgcaggg agctggtaaa acgacctttg caggaaaatt
     5881 agccaataag ctcatcaagg aagaaaatgc tcgtccattg atgattgcag cagacatcta
     5941 tcgtccggct gctattgacc agttgaaaac cttgggacag caaataaatg ttcctgtttt
     6001 tgatatgggg acaaatcatt cagcagttga tattgttgcc aatggtttgg cacaggcaaa
     6061 agagaaccgt catgactatg ttttgattga tacggcagga cggttacaaa ttgatgagaa
     6121 actaatgggc gagcttcgtg aggttaaagc actagctaaa ccaaacgaaa tccttcttgt
     6181 tgttgacagc atgatcggac aagaagctgc caacgttgcc tatgaattta acaatcagct
     6241 cgatatcact ggagtagtgt taacaaagat tgacggtgat actcgtggtg gtgcggccct
     6301 ttctatacgt gaaataactg gtaagccaat caaatttacc ggaactggtg aaaaaatcac
     6361 cgatattgaa accttccatc cagaccgtat gtcaagtcgt atcttgggaa tgggagacct
     6421 tcttaccttg atcgaaaaag caagtcagga atatgatgag aaaaaatcat tagagcttgc
     6481 cgcaaaaatg cgtgagaata cctttgattt taatgacttt atcgagcaat tagaccaagt
     6541 gcaaaacatg gggccaatgg aagatctgtt aaaaatgatt ccaggtatgg caactaatcc
     6601 tgctctagcc aatattaagg ttgacgacaa gcaaattgct cgcaagcgtg ctatcgtttc
     6661 ttctatgaca cctgaggagc gtgagcagcc agagctttta acaccaagtc gccgccgtcg
     6721 cattgcagct ggatcaggta atagtttcgt tgaagtcaac aaatttatta aagattttaa
     6781 ccaagccaaa gccatgatgc agggtgtcat gtcaggtgat atgactaaaa tgatgaaaca
     6841 aatgggaatc aaccctaata acctccctaa aaacatgcca aatatgccag gaggcatgcc
     6901 tgatatgtct gcccttgaag gaatgatggg gcaaggtggt ttacctgaca tgtctgcatt
     6961 gggtggtgat atggatatga gccagctctt tggaggtggt ctaaagggta agattggtca
     7021 atttgccatg aagcaggcca tgaagcgtca agctaataag attaaaaagg ccaagaaaaa
     7081 acgaaaatag actaaaagaa tggttgcctt gtattctgcc tctaatcgtt agatgctatt
     7141 ctaatttgga gtgcaggtca gtagcgacca tcttttttat aaatacaatc actagatctt
     7201 tggttctaac cattaaacat gatatcattt cactattagc tgttagtgcc tgtgctttaa
     7261 ttgctttctg atcttatata gcaaattagc caagtgataa aaaggactga ttgctaggtt
     7321 gaattctcca ataaactctt cgatagttgg actgaaattg gacttaaatg ctgtcaatcc
     7381 gtccttgaag gagccatcaa tgccgcccat attcgcccaa gctatatcat catgataggc
     7441 atccataaag actttaggat aaagcaggta ctgaggataa aactttttaa agtcatcatt
     7501 catgccagca tagagcattt ccatcgtgtt gccatatgaa atcgataaaa tgcccgcaat
     7561 gacaacctca tctggatatt tatccaagaa gtccttgaat tctgatagat aacgctgaag
     7621 cgattgcttt tgatctgtta gtctagccag tcgctttttt tgatgcgctt gcgtttgagc
     7681 aagctcttgt tcaacagctt tcagctgaag ctcgtaattc ttgagttttt ctggaagatt
     7741 aacctttgct aaatgcaaat aagcattgtc gccataagtc gtcatcagct gtctaaaata
     7801 agcttcgttt cttagagcaa ctccttttct cttttcagtt aaagagataa ggtcagcaaa
     7861 tgtatggaga tcagactgat tacctcgata agctatcacg ccacgttgcc tagcatcctt
     7921 catcaatcgc ttggtatgct taggaaagga cgcttcaata tcagcattag tgtaacaatt
     7981 tgcttgaaaa cgcggctgaa tagtatcaga tagcttggtt gttgggcctg tccaatgggc
     8041 accaaatcgc tttaaatgct taataatggt cagagccttg gaattatcag gtgctttctc
     8101 accaagctga tgctgcttta gcagaatcat aggatcaaat ttaatcaaaa gagctctttt
     8161 tttcttacca tatgccttca aggttttaat cgtaaatgcc actagatcag cattggtata
     8221 gtccatcact ggacctcttg gaatataaat catcgtcata ccaaacggca aaggcttaat
     8281 cagcaaggac atagaagcca cctgattatc tccctgaaaa ataccgatgc gttcattttg
     8341 ccactgattt ttaacagctg cccatgagct gctctgcaag aggttaacct gctggtgctg
     8401 tttgacaaat tggtcatgct cttgagctga aataccgatt tttgaattaa aagctacatt
     8461 tatcatcata tttcctcatc tttaagtatc taaatatctg atcttgaaat agatctgctt
     8521 ctacttaatt tattcgaaaa atagtttgaa aaataattgc tttttttgat tttcaatttg
     8581 attattttta gctgctcaaa tgaataatcg atttcggttt aaataagttt aaaaaatagg
     8641 actaattcct aatgaaatca ggaattagtc ctactacttt tatctattta tcagttaccc
     8701 attaggctgt caatcaatcc tctaaagaaa tcaataattt gctgaaggat tccctgtcca
     8761 gtctttaagg cttcagtagc atcaaagttc acgttgatat ttttaaaggt agatccggcc
     8821 ttttcaacaa tactatcctt taaagcattc agcgttttgg tgaagttttc attggaaatc
     8881 acgccactat ttgagaggtt aagcgcgaaa ttgataataa ggttaatctg atcaggtgtt
     8941 actgccttgg ttaacccata atgatctaag gtttctgtta caatttggcg caccttttcc
     9001 tcattaaccc cttctccagc ctttgcgaca gcagctttaa tatcagtaag cgcaacattt
     9061 agcttatctg catcatagcc tgttttacct gcattttcgg tattgatatt agatagggtt
     9121 gatagctcct cttgtgccag cttcttgttt tcctctggga ctttggcacc atttttttcg
     9181 agtgaataat aaataccggc taaagctgat tctccagtaa ctgggattgg tgcagctaca
     9241 gtaatattgg catgctcaat gcccaaggtc acagcggcgt tacgatacat atcttgcgtc
     9301 accttagtga tattttcagg tgttacaata gttaccttaa gcgtttcttt agctcccagc
     9361 ttttgaatcc taactgagga ataaagctgt aggctcggat catctgctac attcatgata
     9421 ctagcatagg cagttgtatt tagggtgctt aatttgttat cagaagcact attgtagtga
     9481 agcaaggcca aggtttgctc tctttgctca gcagacagtg aatagcctaa aacgtaatca
     9541 ggctgaacat aggtttcatc aattacctgt tgaacattat tagctgcagc gtgtactgtt
     9601 tgaagcataa ataccgaagc caaagccata ctggctgcta ttaatttctt ttgataagtc
     9661 atttttctac ctcttttgtg ttataaattt tcctttacga gaatcctcca gaaaagacga
     9721 ttaaagccaa agtatctagg tgcctagtaa gaccgtttta cttagctctg caaagggcaa
     9781 tattcctagt ctttttcaaa atctaacgcc tctattgtag catttttacc tcaataagac
     9841 gattaaaaag ctgaaacaaa gcatagctag aatggccaag cactattttt acaacaaaaa
     9901 aactagtgca taatggcagc ttagatgtag ctactatcac tagtccaatg attatcttat
     9961 gcagcaacca gtctttatga tctgaggttt tcttgatggt tattgtcctt taaatagaaa
    10021 taataatgat catcagtttt gatgacatag ccatttttaa cctcattaat cacgtccttt
    10081 tgatcaaact ggtagtcctt aggcggtaat aactctgagg aaaaaaggct atcataaggc
    10141 acctcaccat tgtaaaaatg gtaatggtca ccatgagagg taacaaaacc atcatccgag
    10201 atagacacaa taatttgctc tgctgctatc ccctcttcct tgctaacttc attaggactt
    10261 ttgtcagtct ctttctttaa ggctttgcac cttttttcca attgatgaga tgattttagc
    10321 ttcttgcctg tgctatcttg ggctttaaag tcacaagcgg acaaaggaaa taatagtaag
    10381 atagtgaata acgataaata agcttttttg gtcatgtttc actctccaat acacgatata
    10441 gtgtttctaa attcattttt aaatgctcta gataagtttt ttgatcagct ggaaccacct
    10501 caagcgggct taggatatca attgctacac cgttactttg agccaaggtt ttggctagct
    10561 tatctgaagc attttcttcg acgaaaatcg tcttcacatc atattttttg ataaagcggt
    10621 caatttgagc taattggcga ggactaggct cttgctcagg agatatccct gcaattccca
    10681 attgctttag atcaaatctc ttagctaggt aggaaaaggc tgtatgctgt gtcacaaagg
    10741 ttttcctacc tagagattca aacttttcct tataggtctt cactaatttt tgagccttag
    10801 ccttaaaacg cttagcattt tgcaaataaa ctgccttgtg agcaggatct ttttgactca
    10861 ataaagctgc aatctgctct gcctcttgac tagctaagat aggatcagtc caagtgtgag
    10921 gatcatacaa ggcatcggta ttcattcctt tttttatggt gaagtgctcc aagccttgaa
    10981 ccttgtctaa tgttagatgt gatgtcccct ccatgactgc taatcccttt ttttccagct
    11041 gtggtgccaa atccgcagcc caagcttcta atatcttgga atggtaaata aagacatctc
    11101 catcgtaaac cttagcaaca actgtcggac ttggctcata cgagtgtatg ctagtgtttt
    11161 gggcaatgac ctgaacatca tttaaatccc cgcaaatctc ctttgtcata gcataaatag
    11221 gataaaagct tgtttttatg accaaaccgg ccttcctact gctagagctc tgatgacagg
    11281 ctgatagacc caaaagtact gctaatagtc ctactgcgac aattgttttc ttgaatcctc
    11341 taatcatatc tactctctta actagttaat gacctaaaaa ggataccatg atttaactga
    11401 aatgtcaata ttttatcatt ttagcgcacg acgtacacgc atgaagaaaa tgcatgtaag
    11461 ccttttttag ccccatgcat tttttaatct atttctagcg ttttgacatt gcaatatcat
    11521 cagtttgtca atttcaatgt gatgacttca tcacattttg ctaaaaaggc catagtgatg
    11581 ataaaaaacc gctaccagaa agcgtaaatg tcttcttgct tttgtcgtga ttttagtgaa
    11641 ccgcctacca actgaactga tgctggctta accatttcct ggccaccatc aaaagcctgc
    11701 ctctcaatta acaagcttac tcaaggaaga ggtgactgag ccatgcatcc gtcttagtta
    11761 tgactaacag cttatcttgg catttcattc atgtaattcc agtggcaggc catcaggatc
    11821 aaaaaagaag gtcatcttct taccagtata atcatcatac ctaagaggct cgacagcaat
    11881 gcccttagcc attaattgtt caatataagc ttcaataggc ttaacatgaa aagctaaatg
    11941 acgaagccca caggcctctt tgtcatattc gggcctaccg atacgcttag gcggtgcctg
    12001 ataagctgga tcagtctttt tattgccaaa aatctctaat tcaatggctc cacattttaa
    12061 atccaatttg taatcatgtc tatcaggccg gtgattttca cgaataatct caaagccaag
    12121 cttattgaca taaaaatcct tagagacctc ataatccgaa acaatgatag caatatgatg
    12181 aatagcctta agctccatat gatttagttc ctttattaaa taaaaaaagt gaaacaaagc
    12241 aatgccaaga ttactttgtt tcacccctcg tagcgacccc tcgcctagat taggcttagg
    12301 ttgacatctg attgtaagag tgattaaagg ccttcaaaac atcgtcaggt gctttgttaa
    12361 actcatactc gtttttgatt gctcctttga caatgattcg ctctgttgcc tcataatccg
    12421 tacaggtgac caaggttacc tcctttagcc ctggtgtgtc attgataaca tctattctct
    12481 caggtgtgac cgtaaagacg gcattgatct cgtactcgta aatacgctcc ttatctgtaa
    12541 ggtaaataga catcccttct tttgctcttt caagcggtga gaataacatt tcagaagagc
    12601 ctgttagtcc aaaaatatga tgactggcta aggagtaatt gttttctcct cccataacct
    12661 ggtcctcttt catggtacca gcaccgtata taagctctgt gttgccaagc cctttaaaga
    12721 ttggtaggtt aataccaagc tctggtatgg caatacctcc tattactgga agctgctggg
    12781 cgtccatttg agcctgtaag acactttcgg tgctaactgg ctgaactgct tgaaaatcaa
    12841 agcttgactt tgcttcctta ttctttttaa tcgtcttttt tgaaaccttt gtaacttgat
    12901 atttattaga attccaagca atcagggtgt ttctaatggg cttgttaaat aacaaggcta
    12961 agcctatgat taacaataag acgactagaa tacctctagc aaaggacatc tttcttcgtt
    13021 tttgtcttct cctgtgggtt ctttttgcca ttcatttact ccttgctaga atttattggt
    13081 gcttctgtta aagctgtatc agtctgagcg attgctgttg gatcgttgtc ttcagcctgt
    13141 accaaggtaa aggtaacaat cttagaatct gtatctagcc tcataacctt aacaccaagt
    13201 gttgaacggc cagtctgaga aatacttgaa acattggtac gaataatcac acccttcgtt
    13261 gtgatcacca taatatcctc actgccatca acagtcatca ggccagccaa ctggccattt
    13321 tttgcggtga tattagctgt tttgattcct tttccacctc gacccttagt tgggtattcg
    13381 gctgcactgg tacgcttacc atagccattt tcggtgatga ctaagacctc ttgcttgtca
    13441 ttgatacgag aagctccgac aacccaatct tcctcacgaa gcttgacacc acgaacaccc
    13501 gtagcgctac gccccatgcc tcgaatggta gcttcattaa agcgaacaga ataacctgat
    13561 cttgttccaa tgataatatc ttcctgacca tttgtcaaga gaacattaat cagctcatct
    13621 ccttccttga gattaagggc tcgtagacca ttctgacgaa tattgctaaa ctctgatacc
    13681 tcagttcgtt tgacaatccc ttgctttgtt gtaaagaaga aatatttatc aagaatgtct
    13741 tcttttttag cattgataat tgtttgaatg gtttcaccat catctagctt tagtagattg
    13801 ataacaggaa gtccttttgc agcacgtcca tattctggaa tctcataggc ctttaagcga
    13861 tagacgcgcc caaaattggt aaagaaaagc aatgtgtcat gtgtacttgt tgagacaagc
    13921 tcacgaacaa agtcatcgtc attgacacct gttccctgta caccacgacc accacgcttt
    13981 tgagatcgaa actcgtcttg agcaaggcgc ttaatgtagc cattgtttga tagggtgatc
    14041 aaaacatctt cttcctcgat caaatcctca tcttctaatg acaatacctc accaatcatc
    14101 aattctgtgc ggcgaggatt agcgtacttg cgcttgatct cctccatttc ttccttgatg
    14161 atggcttcga tacgctctgg ccttgccaaa atatctgcca aatctgcaat caaagccagt
    14221 aggtcatcgt attctgattg aattttatca cgttccaagc cggtcaaacg gcgaagacgc
    14281 atgtctaaaa tagcctgact ttggcgttca gacaagtcaa aacgagacat caattctgct
    14341 tgtgcgataa tatctgtctc gctattgcgg ataatggcaa taacctcatc tagatggtca
    14401 agagcgataa gtaagccctc taaaatgtgt gccctagctt ctgccttgtc cttgtcaaat
    14461 tgagtcctgc gtgtaatgac gtccttttga tgtagaatat aattatcaat aatctgtctc
    14521 agtgacaaga ttttaggaat cccgccttca atggctagca tattgaagct aaagtttgtc
    14581 tggagacttg tcaatttgaa taggttattt aaaatcacat tagcagatgc atcgcgacgg
    14641 acttcaatga caaatcgtac cccttgtcgg cttgattcgt cacgaacagc tgtaatgccc
    14701 tcaatacgct tttcttgggc taagcgaaca atatgctcat ggacctttgt tttattaatg
    14761 ccataaggga attctgtgac gacaatccgc tcccgtcctg tactagtggt ttcaatctcg
    14821 gtgcgtgaac gcaaaacgat tgatccctta ccagtctcat aagccttatg aattcctgaa
    14881 cgtcccatca ccaaggcacc tgtaggaaaa tccggccctg gaagaacctc cattaaatct
    14941 ctggtagtgc agtcaggatt ttccatgacc atcttaacag cgtctatggc ctcagctaaa
    15001 ttatgaggtg gaatattggt agccatacca actgcgattc cggtggcacc attgaccaat
    15061 aaattgggga agcgagccgg taagactaag ggttctcttt cattaccatc gtagttatcc
    15121 tgaaagtcaa cagtattttt attaatatcc tttaagagct ctagcgcgat tttgctcata
    15181 cgagcctcag tataacgctg agccgcagca ccgtcaccgt ccatagaacc aaagtttcca
    15241 tgaccatcga caagcatgtg acgatagctc caccactggg ccatacggac catcgcttca
    15301 tagatggacg aatccccatg tgggtggtac ttacccatga catcaccggt aatacgagca
    15361 gattttttat gtggcttatc aggtgtgacg cctagctcat tcatgccata aaggatacga
    15421 cgatgaacag gctttaagcc atctcgtaca tctggaagtg ctcttgctac aataacgctc
    15481 atagcataat caatgaaact cgttttcatc tcacttgtca gattgacgtc aactaaatgt
    15541 ttatcttgca tttaaggaat gctccttttc tagtcaatac tcttttaatt ataccataaa
    15601 atccttattt tttctgattg gaaacgctgt ccgaaaacaa ttttcataat ttggtcgaat
    15661 atcatgacaa agacattaaa atgtgttaaa ataagatcgt atgagcaatt tgctctaact
    15721 aaaatgaagg agatgtttag aaatgactgc aactaaacaa cataaaaaag tcatcttggt
    15781 tggcgatggt gctgtaggct cttcttatgc ctttgcacta gtaacccaaa atattgccca
    15841 agagcttggt attattgata tttttaaaga aaaaactcaa ggagatgctg aggatttaag
    15901 ccatgcgctt gcctttacct cccctaaaaa gatctatgct gctgattatg ctgactgtca
    15961 cgatgctgac ctagttgttt taacagctgg cgctcctcaa aagccaggtg agactcgtct
    16021 tgaccttgtt gagaaaaatc tacgtattaa taaagaagtg gttactcaaa ttgtggcctc
    16081 aggctttaag ggaattttcc ttgttgctgc taatccggtg gatattttga cctattcaac
    16141 ctggaaattc tcaggtttcc ctaaggaacg cgttatcggt tctggaacat cacttgactc
    16201 agcacgcttc cgtcaggcac ttgctgccaa aattggtgta gacgcacgtt ctgttcatgc
    16261 ctacatcatg ggtgagcatg gagattcaga atttgctgtt tggtcacatg ctaatgttgc
    16321 aggggttgga ttgtacgact ggcttcaagc taatcgtgac gttgatgaac aaggcttggt
    16381 agacctcttt atctctgtac gtgacgcagc ttactctatc atcaataaaa agggtgctac
    16441 cttctatggt attgcagtcg ccctagcacg tattacaaaa gctatccttg atgatgaaaa
    16501 tgcagttctt ccactttctg ttttccaaga aggccaatac gaaggcgttg aggattgcta
    16561 tatcggtcag cctgctattg ttggtgccta tggtattgtt cgtccagtca atatcccatt
    16621 gaatgacgct gagcttcaaa aaatgcaagc ttcagcaaac caattgaaga ctattatcga
    16681 cgaagccttc tctaaagaag agtttgcgtc tgctgctaaa aactaattaa aaaatgaatg
    16741 tgttagatct tgctctaacg ttttggaatc actacaaaaa gcctaatcca atcggatagg
    16801 cttttttcat gcgtctaaca gcgaggtgca agacaaagca cgctttcatt aagcatcgtg
    16861 tgtgctatgc ttatagtctt aagtcacaaa aaagacaacc agctttatga gctggctgct
    16921 tattagcttg ttattcagca ccaagtgctg ccattgtaat gtagttatat ggcttgttaa
    16981 agtgcggtaa gaagaaaata tcagtcaaag ctaatttctc aatggtcact ccttcttgga
    17041 tagcaagtga gaacatatga attcccattg aaatatcttc atgtgaggcc atttgagcac
    17101 ctagaatacg acgtgattct ttatcgtaga caatcttaat ggttacttgg aagttaccat
    17161 gctcgataaa ttctggtttt tgattgtcag tgtattctgt tactgctgca tcaaagccaa
    17221 ggcattttgc tttctcaaga gttaagccag ttgataccat gtgcaagccg tagatagaga
    17281 taccatttga tccctgcaca ccaataccct caagagctgt gccacaagcg ttatgagctg
    17341 cgacaatccc tgtacgaaca gcatttgaag caagggcaat ataattggta tcgcgagttg
    17401 cgttgtcata gatggttgca caatcaccga ttgcataaat ccctggaata gatgtttctt
    17461 ggtgtttgtt aacaaggaag gcaccattac ggaaaagctc aatcttgcca gcaccaagag
    17521 ctgtatttgg acggaagcca actgcaagga taaccatatc aacaccatat tcattcttat
    17581 cagtgattag cttttcaacc ttgccatcac cagcaacctc tttgacagtt tccccaaagg
    17641 ccaactgaat accatgctct tctaggtttt tagacatgac atctgtcaaa tcacgatcat
    17701 agtagcctgc tagacaagta tccgcaacat caatcagaat aacctctttg cccttacgtt
    17761 ggaaggcttc tgcaagctct acaccaatgt agcctgcacc aacgactgca acgcgcttaa
    17821 tgtctttgtt ttctaatttc gaaatgacat ctgctgaatt ttggtacaat ttaacgaatt
    17881 gaagattttc aagtgttgct tcaaactcta atgagccctc tttgatttct gcacctttaa
    17941 ttggtggcaa gataggctgt gaaccagttg caaaaattaa tttgtcatat gactcaacat
    18001 gctctttgcc atcaacaagg gctgtcactg ttttagcatc gtagtcaata gattgaactg
    18061 gtgattccat gtaaacctta gcaccaaggg actctagctc ttccttattt gagtagaata
    18121 agccctctgg gccagaaatt tgttcgccaa tccaaagtgc cataccacag cctaagaatg
    18181 aaatatttga gttttggtca aatacaacaa tctcattagc atcaccatag tttgttaaca
    18241 tagtcttgat acatgccgta cctgcgtggt ttgcaccgat aacaacgatt ttactcatat
    18301 gattatgttc ctcatttcac aatttatatt aggtctctat tataacacag ggaaaaagcg
    18361 cttccaacta aaatgctcat ttttcttgct tttttatacc gttttttagt caataaataa
    18421 gacagcctat catttgttga agggtcgtac aaagaccggt ttgcttcagt taagtcaaga
    18481 cgacattctt attcaactat tttcccaaat tcattacatg attaagacca ttttttgtcg
    18541 ttaacttcta aaaaagactc ataagctcaa tcaggtaaag attgacatgt acctcttgag
    18601 cataataaat attgccgccg ttgcaataaa gctttccacc agagaggagg gctaaggggt
    18661 ggtaataaaa ataggttttt ccagtagtat ttcctaggct gggtgcaacg acagttctag
    18721 aatagttagt ggctagttca attgtatgct gaccgccatt tttagcaacg taatcaatat
    18781 aggcggttcc aaaattgtaa gcttgaacag ctgtccaagg gtctacgccg gctttttctg
    18841 ctaaagctaa attgtgagat agcaatctga caccatactc aatgctagat tgactatcgg
    18901 tgatcgaatc ccttatgcca gagctgcttt cgcttgactg cataacgtca gcttctcctc
    18961 ccttagtttc cgtgtatatc atggctagta ccagatcgac gtctgctttg ttaccgtttt
    19021 ctgctaaaat acgctctact gttggcttgt attgtaggac tctgtgcaca ttcttatgaa
    19081 tggtaactgc ttcgtacagg caaaaaatga ggacggctaa tcctaagata cgctttaaca
    19141 ctctaaacat ttagttattt ttgatatcct ctatattttt tatcaatatg gaataggttc
    19201 cgttgtcatt caagataaac tctactgact cagcatcttg ataaactgca ttagggacaa
    19261 gaagctcaat tccatttgac agcgacagct tttgcgtctc tagctttttt agctgtctag
    19321 aatgatcaat atcactgacc tgaattggtt cgggaatcat ttccttgacc tgatccacaa
    19381 aggttaacct tgcagtcagg ttctggtcaa ataattgatc tgctagcttt tctggagata
    19441 gagctgtttc ttcttctaga tttttagcca gtgctacttt catctttgat tgaaaagcaa
    19501 agtcatcttg gttaaaattc tcggcaacct tttgagcggt ctgctcaagc atttgaatag
    19561 attttttgac agattgctca ggtgttacct ttagcagctt ctcagaaaag taatgagcaa
    19621 agcttccatt gtgcttcatg cgtttttcga ttaagtagta atagcctgtt tgacggttaa
    19681 tgaccaaggc ttcatcaggt gcctgagtag ggcttggcaa attattttgc gtgatcgtaa
    19741 taggattttc atgatcgtct gatagatggg caaaatgctc ttttagggca atgcgtaaaa
    19801 aggccagata aggcactcct tccttatcaa actgaataaa aaccaaatcg tttgtctttt
    19861 gatgttcaga agcgacaaat tcttccttcc aaagcttggc aattgttact gatgtttcca
    19921 aaagctctgt accgattgtg gtaaaaaaag catgatcagc ttctaattgc ccacgtttag
    19981 cgtcgtcaga aaaaaccttg gctaattttt tgcgaaaata ctcatcaatt cttggtgtta
    20041 tagctactaa agcatctgat aagatcagct cggtatcgtt tggtgtgaat tggtggatca
    20101 caattccttt tatataaata tctagcattg ttagttcttc ttgtataatg ggaaggcgtc
    20161 agtcaatcgg cgaacctcat aacggacctc ttcaaggatt tcaggctgct ggtggttaac
    20221 caaggccttg ataattaaat gagcaatagt cctactttcg tctactccca ttccacgact
    20281 ggtaatggca gcgcagccta tgcgaatgcc tgatgtttta aagggagata gggtctcaaa
    20341 aggaatagca tttttgttaa gggtaatatt aacctcatca agcaaggctt gagcaagctt
    20401 gccattttca atcaccttag tcacatcaac aaggaaaaga tggttatctg taccgcctga
    20461 gatcagacga aaacgatcat ccttggcaaa aacctctgcc attgctgctg tatttgctat
    20521 aacagccctt gcatagtctg taaaggcagg atcaagcgcc tccttaaacg caacagcctt
    20581 cgctgctatg acatgctcca aaggcccacc ctgtagacca gggaaaatag ctgcattcat
    20641 tttccttgaa attgcttcat catttgtcaa aagcaggcca ccacgaggac cacgaagggt
    20701 tttatgagtg gttgaggtca caatatgagc ataaggtact ggattttgat gcagacctgc
    20761 tgcaaccaag cctgcaatgt gtgccatatc caccatcaaa taggatccca cctggtctgc
    20821 aataaaacga aattgctcaa aatcaatctg ccgagaatag gctgaggcac ctgcaacaat
    20881 caacttaggc tgaacagcct tagcttgctt taggatagct gcgtagtcca gcttttcagt
    20941 ttccttatcg acagtgtagc cgacaaattg ataggttttt ccagaaaaat tgacaggtga
    21001 gccatgtgtc aagtgacctc cagctgccaa atccatacca agcacagtgt caccagcatt
    21061 aatcagtgcc atataagcag cagcattggc ctgactacca gaatgaggct gaacgttggc
    21121 ataggctgca ccaaagagct ttttggcacg ctcaatagca aggctttcaa caatatcaac
    21181 atactctgtg ccgccataat aacgcttgct tggatagccc tcagcgtatt tgttggtcaa
    21241 gacagagcct tgtgcttgca taacagcctt tgagaccata ttttcagaag caattagctc
    21301 aatattatgc tcttgcctgt cctcctcggc ctgaatagcc tcccaaagct cctgatcata
    21361 gtctttgtag ttctcgttgt taaacatcat tattgtctcc tctataatag cttcataaat
    21421 cgtaattgtg tcttatcatc tacatagctc agcttacggt aaaaggcatg tgcctcggtc
    21481 ctgtgactag cagaattaag ccgaataaag cttactttct cctgcttagc cttctcctct
    21541 aaagcagcta gtaagcgacg accgatacct ctaccttgat ggtccagcct cactgctaag
    21601 gccaaaatat taaagccttt ttccgagtaa agcgactcgt agcattcagc atgcagatag
    21661 cctaagagca gattggtctt agtatcagca tagcccagca aataatgatg cttatcggat
    21721 cttagttttt ccaattggct ttttgtcaat tcaagagaaa ccttgtaccc caaggattga
    21781 tcattaatgt cacaaatagc ttgacaatct gtttgatcta gtggtcttag catagcctta
    21841 cctcctctaa aatggcagct ctggaacctt agctaataat tgctccttag taatagcacc
    21901 ttgtcgtaaa atactgacct taggtgacga taaatccaaa atagtagaat ccttccctgt
    21961 caaataggca tcatcagcat aaccatcaac ctttccatca aatgccttga caatgtcatt
    22021 aaagcatttt ccactctttg agcctgacag gttagcagat ggcccaatca agggacccgt
    22081 tgctctgata attttagctg tgagagggtg actgggtagt cgaaagccaa ctgtttttag
    22141 cccagaatta atccaatagg gtgtctgggc attggctttt aggataatcg taagtggacc
    22201 aggtaaaaaa gcctcgtaca gcttgttaag ataggcaggc tgctgcttag aaaaagccaa
    22261 aatactctca aaatcagcca cattaaggtt catagccttg tcgcgaggcc tttttttgag
    22321 acgataaaca gcattaacag cctcttcatt taaggcctga gcaaaaagac cataaactgt
    22381 ctcagttggt aaaataagag ctccaccagc cttaattgtc tctatcaaat gtgttatcat
    22441 caacaaccac cattctttct ttacccagca tatccttaag cactctgata cgcttttgag
    22501 ggaaacgctt ggataagagc ctttttaagc cttctccctg cttgtagcct atttcaaaat
    22561 agagcttacc acttgtcgtc agataagcac tagcttgttc gataatgcgt cggtaaatag
    22621 aaaagccatt ttctgcagca aataaggcca aatgcggctc agattgataa acattcaagc
    22681 caacctcgtc cttatcctca taggcaatat agggagggtt agaaacaatg atgtcaaact
    22741 gccctgatag cttgctaaaa aggtctgact gctcaaaggc tatctctaca tgatgatcta
    22801 aagcgtttga gtaagcaagg ctcaaggcat cagctgaaat atcagaggct gtgacctgcc
    22861 agttaggtct tgcttttttt aaagcaattg caatagcacc actgcctgtt ccaatgtcta
    22921 aaacggattt gcgagtagcg tcattttcct tcaagataag ctcaactaat tcttccgtct
    22981 ctggtcttgg gattagcacg cgcgaatcca ctgcaagcac cagatctcta aaataagccc
    23041 tgcctgtgat atattgtggc gatacatgct ggctaagcgc taaaaaaatc cgctctaata
    23101 aggcttgatc ctctgaagtg acctcttgat tttgatgaag caaaaagtca aggcttgtcc
    23161 actgctttaa ttctttaaaa acataggcga ggttttcacg atcctcacct atgttttcta
    23221 gcctgtcttc gtaggctctt agttgcttag catagttcat tggttattta gcgattctaa
    23281 tttctgagtt tgatcatata gcactaaagc gtcaacaatc tcgtctaact ttccagacaa
    23341 aatggtgtct aatttttgca gggttagacc gatacggtga tctgtcacac gattttgtgg
    23401 gaaattatag gtccgaatcc gttcagaacg atcacccgta ccgatagttg atttacgctc
    23461 tgcgtcctgc tcgtcctgtg cgatctgtgc aaaatgatct gctacacgtg cccgaataat
    23521 cttcatagcc ttgtcacgat tcttttgctg cgttctttcc tcttgcatct caaccttgat
    23581 gtttgttggg agatggacga tacgaacagc ggttgccacc ttgttgacat tttgtccgcc
    23641 agcaccagaa gcatggtaaa tatcaatacg aaggtccttt ggatcaatgt cgtactcaac
    23701 ttcttctacc tctggcatga ctaagacagt cgcagttgaa gtatgcacgc gcccttggct
    23761 ttctgttaca ggaacacgct gtacgcgatg agcacctgat tcgtatttta gcttggaata
    23821 aacagattgt cctgaaacca tagcaacaac ctctttaatc cctccaacac cattatagga
    23881 agcctccatt acctcaaagc gccagccttg gctttcggca aatttttggt acatggctaa
    23941 gagatcaccg gcaaatagag cagcctcatc accacctgcg gcaccacgaa tttccaagat
    24001 aatattttta tcatcatttg gatctttggg aagcagcaaa agctttaact tgtcctcata
    24061 ggcttccttg gcagacttgg cctcttttag ctcctccttg gccatctctt caatgtcagg
    24121 atcgccgccg gcttccttaa tcatctcctc agcgtcatca atggattgga taatagcctt
    24181 atactgacga taagctgcta ctgtttctcg tgtgctagcc tcttcctttg acagagccat
    24241 aaaacgtttg gtgtcagaaa caacctccgg atcacttaat aattcgccta attcttcata
    24301 acggtcctca acagcctgta attgatcata aatattcatt agggggtatt ctctcctctt
    24361 tttacttgtt ttagttgtta ttagattggt gggtgaaaat aatgcttgcg acaaactgga
    24421 atataggtct cattgccacc aatttgaatc tgtgctccct cataaacggg cttaccatgt
    24481 tctgttcgca ataccatagt tgcttttttg ctgcaatatt gacagatggt ttttatctca
    24541 tcaatcttat cagctaacag taacaggtat ttggagcctt caaacaattc attttgaaaa
    24601 tcatttttta agccaaaggc catcactgga acatttagct catcaaccac acgtgctaaa
    24661 tcatagacat tttgcttgct taaaaattga cattcgtcaa tcaagacgca atagggcttc
    24721 tcctgcaatt cagcaataaa tgcaaaaata tccatatcat tcgaaattgg tacagcctca
    24781 cgacgcatgc caatccgact agaaacaatg ccaaagccat cacgtgtgtc tagcgcactt
    24841 gtcataatca caacaggctt cccctgttct tcataattgt gtgctacctt caagatttca
    24901 atggtctttc ctgaattcat tgttccatat ttgtaatata attgagccaa aatggagatt
    24961 cctaccttct tcttttgtcc tacttattct atcatatttg tccctatttg gcgattgcct
    25021 tatctgaaaa tcttattttc acaacagcta aatcctgtgc tgttgagcta aggttaggct
    25081 ttttgaagct gacatgctac aatagaggta tcattaaaaa aaggagattg actattatgc
    25141 catttgtaac gattgacctg tttgaggggc gtagccaaga acaaaaaatt gccctagcgc
    25201 gtgaggtgac agaggttgtt tctcgtatcg cacaggctcc aaaagaagcg attcatgttg
    25261 taatcaatga catgcctgag gggacctatt tcccgcatgg tgagatgaaa accaaagcct
    25321 aatgcctaag tcccacttat ctaggtgggc ttttcctatt tgaaaaggag ggcctgatga
    25381 tagctactga tcagatcaag atgatgggaa caatcattga tatttgcatt gactcatcaa
    25441 aagcaaagca gcaagcagct actatccgag agctactaac cctttacaat caccgttttt
    25501 cggccagtga cgacagctct gaattaatgg caatcaacca tatggcaggt attcagccag
    25561 tgcgtgtgca ttcagatttg tttgacttaa tctcaatcgg aaaagagcat agcttggctt
    25621 atccaagcaa ccttaatatc acacttggtc ctttagtgca aagctggcgc atcggctttt
    25681 cagacgctaa gcttccagat gaagcaacta ttgatcgcag actaagacta accaatccta
    25741 atcatatcat c
//
LOCUS       DARYMD010000030        25543 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYMD010000030 DARYMD010000000
VERSION     DARYMD010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25543
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..313)
                     /locus_tag="TU818_001205"
     CDS             complement(<1..313)
                     /locus_tag="TU818_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0924025.1"
                     /translation="MDVKIQDIRKSYKDRDILKGVSFEIQKGTICGLLGINGAGKSTL
                     MKIIFGLEKADSGNVIFYNQKDQHVNYEIGALIESPAIYMNLSAFDNLKTRALLYNIS
                     GE"
     gene            complement(797..2149)
                     /locus_tag="TU818_001206"
     CDS             complement(797..2149)
                     /locus_tag="TU818_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0924026.1"
                     /translation="MTKTYSIRYRVGITVGEILIGIAILVISLLIIPYLLVFTKQLNI
                     HGTSFDIVLGDKVSTEEITKQMDTLTFDYVLFNRKNGEVLNGNYQKTELSYYETVFED
                     KKPINVGTIDYKAYSNDQILLVVRQPTLPEFVNPSLRKVSFNTLSIILFIVGTLSIVF
                     ISVTKLLREFAHDFRLIQKISLNMGSRDYKIERSTTKISEFNDILAMLYQKDDELTIL
                     LEAERAEKKDLSFQVAALSHDIRTPLTVLKGNLELLEMTDLSNQQISFIGSINHSVSV
                     FEKYFNSMITYSRLLIEERDYQEVIEVTEFMSGLQIEIQEIMHTEQVDFDMKNNLRIT
                     HFKGNRFNLERALINILVNAAQHATDVKQVSLTAKEEQDQLIFEIWNSGSKFSKQALN
                     GANKLFFTEDNGRSSKHYGIGLSFAQGVAVRHQGKLQLLNPLKGAQVNLIIRKYELLL
                     "
     gene            complement(2142..2825)
                     /locus_tag="TU818_001207"
     CDS             complement(2142..2825)
                     /locus_tag="TU818_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0924027.1"
                     /translation="MYKILVVDDDYEILKLMRTILEMKNYKVTTYQEVTFPINFRDFQ
                     GFDLILLDVMMPNVEGTQICQLIRDKVASPIIFVSAKDTEDDIIKGLNLGGDDYLPKP
                     FSVNQLIAKVSAHLKREERVKHGENVEKITRELLPITFYLQEKMLCVSGKPVPLTSRE
                     YHILELLSSHPNKVFTREDIYEHVYDDEANALFRSISEYVYQIRIKFAPFNLNPIKTV
                     RGVGYKWYD"
     gene            complement(2862..4238)
                     /locus_tag="TU818_001208"
     CDS             complement(2862..4238)
                     /locus_tag="TU818_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL0924028.1"
                     /translation="MLTMKHKMLIFCLLLSIFVSQFHMLHVYAETSSKTQYNILIKES
                     LDTNKVKKQLNDQGMIVLDEIPEINVLTIAAANDSSMILEKNCNYIDDISRNNTFTVN
                     PKMTYQFGHAFYLDSDLNYWNKQWDMQRSISTSSRFWHKSSGEVTIGVIDSGITDNNT
                     DISSKIISVQNFTEDPVTKAIDVNNVLDKTGHGTSVVGQMSSNGYYTGIAPGMKVRMY
                     KVFEEGNAQDEWILKAIIQAAKDDVDVINLSLGQYLLKASSNIDEDRTALINSYQRAI
                     NYAHKQGSVVVASVGDEGANLNNQAELKNLVSALTGRAFSSVDGTIEDIPAQLDNVVT
                     VGSVDGDGAISNFSNRGRNVVDIFAAGGGSKKLALHGYDTWINNKLFEQDWVIIPTLE
                     GKYTYGYGTSIAAPKVAAALGLIIEKYDLKDKPDEAITILYSNSWSSLDDNGKPIRLL
                     NITDFISK"
     gene            complement(4406..4537)
                     /locus_tag="TU818_001209"
     CDS             complement(4406..4537)
                     /locus_tag="TU818_001209"
                     /inference="COORDINATES: protein motif:HMM:NF022534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924029.1"
                     /translation="MEEETKLNQETMTTMIGKYECYARQLEKLAFVFNYKSELRTKD"
     gene            complement(5646..7592)
                     /gene="thrS"
                     /locus_tag="TU818_001210"
     CDS             complement(5646..7592)
                     /gene="thrS"
                     /locus_tag="TU818_001210"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL0924030.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIRVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGADYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPRQVTVIPISNEAHIDYAWEVA
                     KILRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAISAFVDNILADIARKSRPAEG"
     gene            complement(8183..9517)
                     /locus_tag="TU818_001211"
     CDS             complement(8183..9517)
                     /locus_tag="TU818_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL0924031.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIKKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSLGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDKMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSGSIKLVQGAIHLPKRAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            complement(9519..10517)
                     /locus_tag="TU818_001212"
     CDS             complement(9519..10517)
                     /locus_tag="TU818_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL0924032.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYEGWIDQ
                     DSAELANDTSGFVAALRRILSGESNKTEAGYRVAEGRSLDRIAHQLVAIYQKVMEL"
     gene            complement(10813..12288)
                     /locus_tag="TU818_001213"
     CDS             complement(10813..12288)
                     /locus_tag="TU818_001213"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL0924033.1"
                     /translation="MSHQLLMQAFEWYLPADGRHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFNQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQALTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDAKANETGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQPLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            complement(12358..13359)
                     /gene="ccpA"
                     /locus_tag="TU818_001214"
     CDS             complement(12358..13359)
                     /gene="ccpA"
                     /locus_tag="TU818_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL0924034.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            13533..14618
                     /locus_tag="TU818_001215"
     CDS             13533..14618
                     /locus_tag="TU818_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL0924035.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIKSVLPSTAAKTIYAEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(14792..16375)
                     /locus_tag="TU818_001216"
     CDS             complement(14792..16375)
                     /locus_tag="TU818_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924036.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMVRAFNCLIAKKALYHFYHKQLNYFTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLASITDFTKGADTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVSPLIIGLLVMSYSSLSLTTLIAMITASTNLVS
                     PLQQLLEATSSLQSATAVKEKMVRVLALEEETKHQALTPTDDLTLDIYFKRLDKYFDH
                     RLIFQGIDGHISAGHKTLLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLILKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKELVRCS"
     gene            16613..17464
                     /locus_tag="TU818_001217"
     CDS             16613..17464
                     /locus_tag="TU818_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0924037.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKIAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQLQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFFLEYWTNLDVGLLGNIVHY
                     MTTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            17725..18393
                     /locus_tag="TU818_001218"
     CDS             17725..18393
                     /locus_tag="TU818_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL0924038.1"
                     /translation="MSHKSIHQQLRNAFSFRTAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADDPRALFDWTAKQTYIALANMMTTAAFM
                     GIDSCPIEGFNYDKVNAILAKHGIINPDTEGISSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            18508..19434
                     /locus_tag="TU818_001219"
     CDS             18508..19434
                     /locus_tag="TU818_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0924039.1"
                     /translation="MTLLSVIIPCFNEEDTIIPYLEEMKQIEAAMTSQLAFEYLFIDD
                     GSTDQTLSVLRELAGRFSNVHYLSFSRHFGKEAGLLAGLEEAKGSYITVMDVDLQDPP
                     ELLPLMYSKLQEGFDVVATRRQSRQGEPAIRSFFARLFYRLVKHVSNTEIVDGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYNTAYISFDNRKRQYGKTSWNFLELLNYSI
                     DGFINFSEMPLTIATWTGTLSFLLSLLAICFIVIRKLLFGDPVSGWASTVSIMLFIGG
                     IQLFCMGIIGKYISKIFLETKKRPVYIIKEKK"
     gene            complement(19418..19606)
                     /locus_tag="TU818_001220"
     CDS             complement(19418..19606)
                     /locus_tag="TU818_001220"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924040.1"
                     /translation="MTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQSLS
                     ASLAADRGLDDCSVISFL"
     gene            complement(19718..20185)
                     /gene="smpB"
                     /locus_tag="TU818_001221"
     CDS             complement(19718..20185)
                     /gene="smpB"
                     /locus_tag="TU818_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL0924041.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLIPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(20188..22512)
                     /gene="rnr"
                     /locus_tag="TU818_001222"
     CDS             complement(20188..22512)
                     /gene="rnr"
                     /locus_tag="TU818_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL0924042.1"
                     /translation="MMIENITNYLKEHGQSNIHDLAAALEMTDARSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRVQGIFRANKAGFGFLSVDDNEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKATAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGTVCDIIGHQHDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDHQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDSEALRE
                     FDRIADDVSTMVELHQILEAMRVKRGALNFDTQEARIIVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAVSSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVIASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFDYLASDYDVVEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRS"
     gene            complement(22599..22835)
                     /gene="secG"
                     /locus_tag="TU818_001223"
     CDS             complement(22599..22835)
                     /gene="secG"
                     /locus_tag="TU818_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL0924043.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLGIALVLAILSSK"
     gene            complement(22881..23027)
                     /gene="rpmG"
                     /locus_tag="TU818_001224"
     CDS             complement(22881..23027)
                     /gene="rpmG"
                     /locus_tag="TU818_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL0924044.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
     gene            23515..25401
                     /locus_tag="TU818_001225"
     CDS             23515..25401
                     /locus_tag="TU818_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0924045.1"
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEKYYGFNDGTGEH
                     SPFPVYVTPITKPNRNTAKVVYCFNKDMKWPETWDKAAPKKPDNLPLYYDMEGTDQLF
                     STYASGQLTPNVSKVLANIMAKGYPNNNEFAHHFKLTPNSAVKVTQIAVWTVTDNLKN
                     YSQYSLTREEEAALNYLTDKNGDDFSDSIKLKLYIPQNPRTIKYQNLLGYDLIVKTPE
                     KKDNCKCTKIYIEDNGKDGYYLYIYYDNNENNRYDSDKDSLLQKKYIKNGKDGKPGRP
                     GVPGLPGPAGPQGPRGDKGETGERGPKGEKGLDGKPGEKGPKGDTGKDGKDGQPGPQG
                     PKGDPGRDGKDGEPGKPGERGEKGPQGERGPQGLPGPKGEPGIPGPKDEDGKDGAPGH
                     DGQPGPKGEKGDPGQQGIPGPKGEPGRDGKDGEKGERGEQGPQGERGEQGPQGERGEQ
                     GPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQG
                     ERGEQGPQGERGEQGPRGENPTPTPDPMPQPEPQPEPQPMPDPAPKPESKPEPKPIPQ
                     PEVKPQPETKPQQPNKPSTITSQSSGKSLPKTNDTGSLITAFGTGLLTLLGLGFLAKR
                     KRKQ"
BASE COUNT         7804 a         5809 c         4640 g         7290 t
ORIGIN      
        1 tttcaccaga aatgttatat aagagtgctc tggtttttaa gttatcaaaa gctgacaaat
       61 tcatatatat cgctggagat tcaattaatg caccgatctc atagttcaca tgctgatcct
      121 tttggttata aaaaatcaca tttccactat ccgctttttc taaaccgaaa ataattttca
      181 ttagcgttga tttcccagca ccgttgatac caagcagtcc acatatagtg cctttctgta
      241 tctcaaatga aactcctttt aaaatgtctc tatctttata agatttccta atatcctgaa
      301 tttttacatc catgattaca cctccttttt tatttaatca tacggtttct ttttcaatat
      361 ttgttcagaa aataatgaaa gcatcaagat ttggaataaa aagaaaatca aacattttta
      421 tagaagcaag caaccaaatg ttcttacaac gtgaatatgg aacctatctt tgtccggtta
      481 aagacttatt tgggctacaa acgttgcata accttcatta tgactaaaag ctataatgtc
      541 agtaaaataa tattcagttg attcttgagt atttaagaat atgaaggcca gcgagttcag
      601 aatatgaaaa aagcccgttg aacgggcgat aatcaagtaa acactgttca gtgattgtct
      661 ttaggctcgg ctgaggagat caacctacag aagccaaggc acttgttttt gaagcaatct
      721 ccaaaaagtt agacagaaac tctaacgaat ggaagtacag ctcatctaac gggtggtcat
      781 gatttaacta tctactttac aggaggagct catactttct aatgattaaa ttaacctggg
      841 cacccttgag tggatttaat aattgtaact taccctgatg ccttacagcg acaccttgag
      901 caaaagataa accaatccca taatgcttgc tgcttctacc attatcctca gtaaagaata
      961 atttattagc accatttaat gcttgttttg aaaacttcga accactattc cagatttcaa
     1021 aaattagctg atcttgttct tcttttgcag ttaagctaac ttgcttcaca tcagtagcat
     1081 gctgtgcagc attaactaaa atattaatga gagctctttc taaattgaat cgattacctt
     1141 taaaatgagt gattctaaga ttgttcttca tgtcaaaatc aacctgttca gtatgcataa
     1201 tttcctgaat ttcaatctgc aaaccgctca taaattctgt tacctctata acttcctgat
     1261 aatctctctc ttctattaac aagcgagaat aggttatcat tgaattaaaa tatttctcga
     1321 atactgaaac actatgatta atagaaccaa taaagcttat ctgttgatta gaaagatctg
     1381 tcatttcaag taattctaaa tttcctttta aaaccgttaa aggtgtcctt atatcgtgtg
     1441 aaagagccgc tacttgaaaa gagagatcct tcttttcagc tctttcagct tctaacaata
     1501 tcgtcagttc atcatccttt tgatagagca tagctaatat atcattaaat tcacttattt
     1561 ttgttgttga gcgttcaatt ttataatcac gactccccat atttaaagaa attttttgaa
     1621 ttaaacggaa atcatgagca aactctctca atagctttgt gacagagata aatacaatag
     1681 atagtgtccc tacgataaac aggataatag ataaggtatt aaaggaaact tttcgaaggg
     1741 agggattaac aaactctggg agtgttggtt gtctcacaac caataatatt tggtcattac
     1801 tataagcttt atagtcaatt gtacccacat taattggctt tttatcctca aaaactgtct
     1861 cgtaataact taattccgtt ttttgatagt tcccattaag aacttcacca ttctttcgat
     1921 taaaaaggac gtaatcaaac gtaagtgtat ccatctgttt agtgatttct tctgttgaaa
     1981 ccttatcacc taaaacgata tcaaaacttg tcccatgaat atttaactgt ttagtaaaca
     2041 ctaacaaata gggaatgata agaagagata taactaaaat tgctatccct attaaaatct
     2101 cgccaactgt tattcctact ctatacctta ttgagtatgt tttagtcata ccacttatac
     2161 cccactccac gaactgtctt aataggattc aagttaaaag gagcaaattt tatacgaatc
     2221 tgataaacat actctgaaat agagcgaaat agagcatttg cttcatcatc atagacatgc
     2281 tcatagatat cttcacgagt gaataccttg ttaggatgac ttgaaagcaa ctctaaaata
     2341 tgatactctc gactcgttaa tggtactggt tttccactaa cacaaagcat tttttcttgt
     2401 aaataaaagg tgattggtaa taattctctt gttatctttt cgacattttc cccatgcttt
     2461 actcgctctt cacgtttcag atgagcactc accttagcta taagctgatt cacactaaaa
     2521 ggcttcggga ggtaatcatc tccaccaagg tttaatcctt taataatatc gtcttcagta
     2581 tctttagcac taacaaagat aataggagaa gcaactttat ctcggattaa ttgacaaatt
     2641 tgtgtacctt caacattagg catcatgaca tctaataaaa tcaagtcaaa cccttgaaaa
     2701 tctctaaaat tgattggaaa agtcacttct tgataggttg ttaccttgta atttttcatc
     2761 tcaagaatgg tccgcataag ttttaaaatc tcataatcat catcaacaac tagaatctta
     2821 tacatagtct tacctcataa tagttacact gttattttac actattttga gataaaatct
     2881 gtaatattta acaatctaat tggttttcca ttatcatcca agctactcca agagttacta
     2941 tacaaaatag ttatggcctc atctggttta tcttttaaat catatttttc gatgattaaa
     3001 cctaaggcag cagctacttt aggggctgca atagaggtcc cgtagccata agtatatttc
     3061 ccttctagtg ttgggataat aacccaatct tgctcaaata atttattgtt aatccaagtg
     3121 tcatagccat gaagcgctag cttcttgctt cctccacctg ccgcaaagat atcaacgaca
     3181 ttccttccac gattggaaaa gttagatatt gcaccatcac catcaacaga tcctactgtc
     3241 acaacattat ctagctgtgc gggaatatcc tctattgtcc catcgactga actaaacgct
     3301 cttcctgtga gagcactgac taagttctta agctcagctt gattatttaa gttagctccc
     3361 tcatcaccaa cagaagcaac taccactgag ccttgtttgt gtgcataatt gattgcccgt
     3421 tgatagctat tgattagagc agttctatct tcatcaatat ttgatgaagc ctttaataaa
     3481 tactgaccaa gactcaaatt tatgacatca acatcatcct ttgctgcttg aataattgct
     3541 tttaaaatcc attcatcttg agcgtttccc tcttcaaaca ccttatacat tctaaccttc
     3601 atgcctggag caattcctgt ataataacca tttgaagaca tttgtccaac aacagatgta
     3661 ccatgacctg ttttatccaa aacattatta acatcaattg ccttagttac tggatcctcc
     3721 gtaaaatttt gaacagaaat gatctttgaa gaaatgtcag tattattatc agtaatacca
     3781 gaatctatta caccaatggt tacctcacct gatgacttat gccaaaacct actactagta
     3841 ctaatacttc tttgcatatc ccattgttta ttccagtaat ttaaatcact atctaaataa
     3901 aatgcatgcc caaactgata tgtcattttg ggatttactg taaaagtatt attccttgaa
     3961 atgtcatcaa tatagttaca attcttttcc aaaatcatag atgagtcatt tgcagcagcg
     4021 attgtcaaaa cattaatttc aggaatttca tcaagcacta tcattccctg atcatttaat
     4081 tgctttttta ccttattggt atctaagctt tcttttataa gaatattata ttgagttttg
     4141 ctactagtct cagcatagac atgtaacata tgaaattgag atacaaaaat agacagtagc
     4201 aaacagaaaa tcaacatttt atgcttcatg gtcagcactc ctttaagtat tgtttttaca
     4261 cttatcgtat gactaacatt tcagatttgt ttcagattct agaaaataat acttactatt
     4321 gtgcttattt aagtccaaaa attagcatta cactcattaa gtatctgaga ttaatctagc
     4381 taacattcta aattgttttc tcccactaat cttttgttct taattccgac ttataattaa
     4441 agacaaaagc taatttttct aactgcctcg catagcactc atacttgcca atcattgttg
     4501 tcatcgtctc ctgattgagc ttagtttctt cttccacctg ctccagttta ctagctgata
     4561 tgcaagtgca atggtcgttt tttgtgaatc acacctactt tgaatctggt aaaatcattc
     4621 tactaacaaa cttcctgtgt aatttctagt agcctaggta gcctgataaa gagatttctt
     4681 caaataaaaa taaccatgtc gaatgccagc gctccatttc ttaccagcat tttcattatt
     4741 ccccagctaa agctctatcc atgaggctaa gtgacctgtg cttagaatta actcatatcc
     4801 acactagtct cagaaataaa gactgaagct atcatgatgt cactactagg aatgaatgaa
     4861 atctagggtt tctacttgac agtcatagtg agacaaacaa gcggcaattt gctcttctaa
     4921 actcccgatt tgtttctaat agcaagcata aatctccata gactaccccc atagaaaatg
     4981 gtggtgattg gagaaatcac cattaagtgc ttcacgacgt tgaggagctt tcttcttcaa
     5041 actagtataa acaattaatg gactacttac tctagctgtc ataggcgttt gagcaatcag
     5101 tagttgaaat agcttgcaac cgaaagcacc cagcatactc tcaatgcgga tcggaagttc
     5161 aatgccacct aactgtagaa ttttataatg caaattgtcc tttattaaga accttattga
     5221 tcattttaag ctttagttcg ggagaggaac gaatcttttt ccttagcagc tttacaatca
     5281 attaatcgtg ctaaatactt taaatggaat tgattgatat caaattgttt gaatgaataa
     5341 ctctggtttt gtaggccgca gatttctacc ttgtcttgat gtcttaatgt catgttaaaa
     5401 gcaccccatt cgttagatag tttgtctaac ttttggggcg cagttcattc attagatttt
     5461 ttatctaatt tttgagaagc agtttacttc tgatgagggc ttctatattg ctttcattag
     5521 ttctatgagt gagagcaaag ctcttgtagc tatttgtccc agattttttt atgtcatctg
     5581 ttttgcaagt caagctgacg tctgcttaat cagcctatct aaaaccagct tgcttggtct
     5641 gctttttagc cttcagctgg gcgtgatttg cgggcaatat cagccaaaat gttatcaaca
     5701 aatgctgaaa tagcttcggt atgtgttgcc ttactgccat agcggcgcac attaactgac
     5761 ttgtcctgca tctccttatc accaacgatt aattggtaag ggattttact ggtttgagag
     5821 gcacgaatct tatattgcat tttctcatta cgatcatcca catctgcacg aatcccatga
     5881 tcacgaagga ttttagcaac ctcccaagca tagtcaatat gggcctcatt ggaaattggg
     5941 ataactgtta cctgacgtgg tgccagccat gttgggaaag ctcccttata ggtttcaatc
     6001 aaaatagcag taaagcgctc catggttgaa atcaccccgc ggtggatcat caccggacgg
     6061 tgttcttctc catcagcacc aatatagctc agattaaaac gctcaggcag taagaagtcc
     6121 agctgaatgg ttgatagggt ttcttcattt ccaagggctg ttttgacctg aatatcaagc
     6181 tttggcccgt aaaaggcagc ctctccttct gcttcaaagt aatcagcgcc catttcatca
     6241 agcgcagcct tcagcatgct ttgagcattt tcccacatct catcgttatc gtaatattta
     6301 tgtgtatcct ttggatcacg ataggacaga cggaagcggt aatctgttag gttaaaatcc
     6361 tcataaacgt caataatcag ctgaagagct cgctggaatt cctcctgaat ctgctctggc
     6421 gtcacaaaca ggtgcccatc gtttaaggtc atctcccgca cgcgctgaag ccctgaaaga
     6481 gcccctgatt tttcatagcg gtgcatcata ccaagctctg caatacgaat cggcagctcg
     6541 cgataggaat gcacatggtt tttataaacc tgaatatggt gtgggcaatt cattggacga
     6601 aggacaaatt cttcaccatc tcccatatcc attgtcggga acatatcctc ctgataatgc
     6661 tcccagtggc ctgatgtttt ataaagctca actgaagcaa gcggcggagt ataaacatgc
     6721 tgatagcctg atgccagctc tttatcagtg atatagcgct caagcgtgcg acgaatcgtc
     6781 gctccatttg gtagccaaaa tggcaagcct tgtcctacct cctgagagat cataaacaaa
     6841 tcaagctcct tgcctagctt acggtgatcg cgctccttag cctcctcaag gcgtgtcaaa
     6901 taggccttga ggtccttttt atcaaaccag gctgtcccat agacacgctg catcatgtta
     6961 ttatcgctat tgccacgcca gtaagctcca gctacattta acaaatgaaa gacccgaatc
     7021 cgacctgttg acggcacatg aggaccacga caaaggtcca caaattcacc ctgacggtaa
     7081 acagttaagc cagccgcatc atctgcatgc tcattaatca actcaacctt ataagggtca
     7141 tccttaaaaa gctcaagagc ctcttctttt gtgatctcct cacgaataca tggaaagttc
     7201 tctttgacaa tttttttcat ttcctcttca atgcgaggca ggtcttcgtt agagatttga
     7261 ccatcagcat tatctgtatc ataataaaaa ccatctgcaa tggcagggcc tacaccaaga
     7321 tgcagcttgg ggaacaagcg cttagcagct tgagcaaaca agtgagccgc agaatgacgc
     7381 agcacctcaa aagcgtcctc atgatcagca gttataattt ctatactacc gtcctcttca
     7441 atggcgcgcg tggtatcaat taattgacca ttaaacttac cagccaaggc ctttttagct
     7501 agagatttgc tgatagagtc agcaatctca aaggttgtga caccagattc aaattcacgc
     7561 accgcgccgt ctgggaaagt gattgtaatc atctgttttc tcctataaac catctagata
     7621 cttaaaacaa gctaatcaag cagggctata tctcccaagc cttctgctgc tacgacaaaa
     7681 taaaaactga ctgcctccca aaggacgcaa tcagcgtggt tccaccttta tttatgcatg
     7741 acaaagaaat cctgtcctgc acctcagctt ggctatatcg tgaccaccgt tttatgtttg
     7801 cataaaagca aggaaggagt attacactag acaccctgtg ctcttctcac caaccagcac
     7861 tcgcttaaag gatgcgacct aatctaactt gtcttcctga ttattatagc aatatttgga
     7921 aataattcaa gtgatttttc ctaaaaaagc tgagataagc ccacagacct ccaagcccac
     7981 aaggcaagaa tgactaggca aggaaccctg aaacttctgc cacaagcctt tgaagaacag
     8041 ctcaaacagg acttgccgcc tgtcgtctca gttcacaaga caacaaacta aatcctttag
     8101 acaaatgatt atcctaaaga gctatctgct ctctcacgca gaaccaaagc ctgtaattgc
     8161 aggcttcttt gtttatttag ccttagtcca aaaagtctcg gatcgcattg accagcttga
     8221 taggggcttt gagcaccttg acagatgtca gtgcagttgc cttagctgct cgcttaggca
     8281 agtgaatcgc tccttgaacc agcttgattg agccactctt ttctgttcga ttgagataga
     8341 gacttagctt tttcgtctct ttattgtgtc gcgaaatcaa ggtatctaaa taaaaggtgt
     8401 acactgattt gccaaaatgc tgagctgaaa tctcatagcg cttctcatct agcagcctct
     8461 ggttcatttg aggtgtttct aaaatggcat caataatcgc atctgacaat tctgactcag
     8521 cataataaag tgttccaaac atcttatcgg taatcaaatc atctaggtag ggattgccat
     8581 gagcgatgat gggcttgcca ctagcaaggc tctcaatata agttagcccc tgtgtctcac
     8641 tcgttgacgc tgaaataaag aaatcacagg ccttataata aagcccaacc tgatcatgag
     8701 caatcatacc agtaaagacc acatgatcct caacgcctaa gctgacagcc agctccttta
     8761 aggcttgaag ataaggacca tcaccaacaa tgacaagctt gatcctgcta ttttcactca
     8821 aaacagctgg cagctgatgg ataatagcct gaatattctt ctcataagac acccgcgaca
     8881 ggctcaatag catggtctca tcatcagaaa tggccaattc ctttctcaag gcagcgacat
     8941 cttctttttt aatatcctca cgaacatagt tctctagtgc aatgccagtc ggaatcacac
     9001 gcttaggaat ggttacctcg tacccttcca aaagatttag cacaatccga cttgggcaaa
     9061 taacaccatc aaggtccttt aaatacccac gaagcagggg cttgaccatg ctaggtcgaa
     9121 tgatcttacc attagcaata tagctcacat aatcctcata ctgggtatga taggtgtgaa
     9181 caaccggaat tcttaaggcc ttgcccacca ttttgcccaa caaacctaag ctaaactctg
     9241 tttgagtatg gataatgtct aaatgatatt ccttagcaat cttgtaggag gaaatgagcc
     9301 cacgataaac cacacgacga tccgtaaagg acacaaaagg aacacttggt aaccgaataa
     9361 tggtcggatc ctcaaagcgc ttaacatgct tgtctgttgt tgtgaaaata tagacctcat
     9421 gcccctcttt ttccagctcc tcctttaggg tgcgaatact ggtagccact ccggaaacct
     9481 gtggaaaata ggtatctgta aatagaccta cacgcatctt ataactccat tactttttga
     9541 taaatagcca ctaattgatg agcaatccta tcaaggctgc gcccctcggc gacacgatag
     9601 ccggcctctg ttttgttgct ttcccctgaa agaatgcgtc ttaaggctgc aacaaagcct
     9661 gaggtatcat ttgccaactc agcactgtct tgatcaatcc agccctcata gactggtata
     9721 tcgcgtaaaa caagatgctg ccggctggct aaggcttcga gaaccacaat gccttctgtt
     9781 tcctcacgac ttgggaagaa aaaggcgtca gccccagtca tagccccctc atacacatct
     9841 cccttgatat aaccagggaa gatcacatta tcggggtgct taccgttgac aatctggcgg
     9901 acacgagcag gaataaccca tttattggta tcaccaaacc agataaaccg aacatctggc
     9961 atcatctcag caaccttaac aaactcatca atcccttttc taagaaagaa aagccccgct
    10021 cccatgacta ccttctcacc ctctttgagg ttaaaataac gccgaaaggc agcttctttg
    10081 tcagcattag caccatattg ctccaaatca atcccattag atactgcaaa aataggagtc
    10141 ttaaccccgt aatgctcaat caaggcttta gaataagggg tcggtgtgat aatggcgtcc
    10201 gccttattgt aaaagcggca gagataggct ttgaataaag gagacactag atttgaaaaa
    10261 ataaaggaat ttctaaaatc ctcctctgtc gaatgcccat gcatgatcac ctttttaccg
    10321 gccttttgag cctttgacat caaaagccag cttttaagcc cataggtatt gagatgaacc
    10381 aaatcatagt cgtcctttgg atcagtggtg aactcctgtc ccacaagcga tagcgctttt
    10441 gcctgatgct taatcgctcg cccgatacct gattttctta aataattttc tgcttctaaa
    10501 tacaataaga ctttcatact gtctattata gcctatttta tggtattttt cactaagaga
    10561 gttaaaaatc agcccttaga ctgattttag ggtaaggctt cttctacccc tatactcatc
    10621 tcaaaaatgc ttttaagtcc tgcttttgct gtcatcaaat ggctgatctt ggtaatatca
    10681 gctagaccaa gatcgtgaaa gctccagctc aaggctcacg tattagccct ttcaagaaag
    10741 cctcccacct ttctcactgg ccaaaaagcc agcaagacct ggccttttct tctgattaat
    10801 tcagcctatc agctaagctt cttcttttgg ctgtgctttt tgtaacaccc aggctgagat
    10861 agagcctgcc tctaccttga aatctgccca gccatcctca gcaacaacaa cagtctcctg
    10921 acaattgtct aagaaatcac aaaaaacttg accagcatag gcttgaccaa cctccatgtg
    10981 cttccagcct gcatcgccat tagacaaaac aactgccaaa ggctgaggac gctgatcatc
    11041 tcctaagcag gtccagccga tacaattggc atgatcaaag taatcaatct gctccccata
    11101 gaccagctgc tgcctgagct ctgccatttt tgtgataacc tccttaaaac tttgctgagg
    11161 gtagtctcca gaaataccat aataatcacc ataaaaaaga cagggcttgc cctcttgtcg
    11221 taaaagaatc aggccatagg ctaagggctt gaaccattcc tcaacagttg actctaaggc
    11281 ttgccctctt tgggtgtcat ggttttccac aaaggtaata gcaaggtctg gccgactagc
    11341 cacaagactg ccatcaaaaa tagtggtcaa atcaaaatca gctccctgct ggctagcatt
    11401 aaaaaaggac atgtgcagcg caacatcaac tagagcaaac tgagccttcg ttgcttcgag
    11461 gtaatcctcc atagattcct gatcagactt ccagtattct ccaaaaacct ctaaatcggg
    11521 ctttagctgg gtacgaatat cattgataaa ggtctgaata aaataagaat caatatgctt
    11581 cacagcgtct aaacgaaagc cctcaatacc agttgtctca ataaaccact tggcccaatc
    11641 ctgtaaattt tggattacct caggatgctt gaaatctaag tcattgtaca ttagataatc
    11701 aaaattacca tgctcatcgt caatcagctc atcattggcc cagcccttgt tatcaccggt
    11761 gatcatgtaa atacctgttt cattagcctt ggcgtcataa tccaatcccg taaaatggta
    11821 ccagtgccat ttaaagtcat tataggtatt ttgtctgccg ggaaaatcaa agcctgtcca
    11881 gccttcaatc tcatagggct ctgtaagggc ctgctgacgg ttctctggat tcattttgat
    11941 cacagaaaag cgttccttgt gatcaccatt agccttgtgg ttcagcacaa catcagcaat
    12001 aggctttatt tttgcctctt ttagggctgc aatcagctgc aaataatcct ctttgctgcc
    12061 atattttgtg ctgacagttc cattttggtt aaactctccc aaatcaaaca aatcgtaaac
    12121 accgtacccc acatcatcag agctagtgcc cttaaaggca ggcggcagcc acagctgact
    12181 aacccctagc tgttgtagct caggaatact gcttttcagc ctttgccaat gccttccatc
    12241 ggcaggcaaa taccattcaa aggcctgcat taatagttga tgactcatct taacctccta
    12301 aaaaggacaa accagaaaac tcctagtttg tcctcaaaac tgcctaaaca ggcagaacta
    12361 ttttgttgtc ccacgctttt taatgccatg gttcaataaa atttcttttt cttctaattc
    12421 ttccttattc atgatcttag tgagcatacg catgctaaca gcccccaagt catagaccgg
    12481 ctggctgata gagctcaaat ttggacgtgt gtactgaacg actggagaat cattgcttgt
    12541 gataatctca aagtcttctg gaacacgctt accagcttca aaaagaccat tcaaaaggcc
    12601 tgctgccagc tcgtcctctg caacataggc agctgtcgct ccggaattga tcacacgctg
    12661 agccagctca aagccttcct tataagaata gttggcctca aacaccagac cctctttaaa
    12721 gtcaagcttg ttcttcttga gtccgtcctt gtagccagct aaacgcacct ttccgttgat
    12781 atcatcaatg agcggccctg aaacaaaggc aatgctttgg tggtctttag ctaaaatatc
    12841 caccacatca gcaacagccg ccttataatc aatgttaaca cttggcagct gatgatccag
    12901 atcaaccgtt cctgccagaa cgattggcgt acgcgaacga gaaaactctg cccgaatctt
    12961 gtcagtcaag tgatgtccca tgaaaataat gccatcgacc tgctttgcaa agagggtatt
    13021 cacaacattg acctctttat catcgtcctc atcacttgaa gcaagaacaa tattgtactt
    13081 gtacatagca gcaatatcat caattccctt tgccagaata gaaaaatagc tatttgcaat
    13141 attaggaatc acaacaccga ctgttgttgt ctttttactt gcaagaccac gagcaacagc
    13201 atttggacga taatcgagac gatcaataac ctctaagacc tttttgcggg tattttcctt
    13261 tacatttttg ttaccattta caactcgact aactgtcgcc attgaaactc ccgcttcgcg
    13321 agcaacatca taaatcgtga ttgtatcatc tgtattcatt cttcatcttc ctttctaact
    13381 gaaaatgacg ctttcaaaaa gtattttagc atgatttgta accactttca agtattaacg
    13441 gttgattttt gaaaaagttt tcaaaaattc ataataagct tgctttttta agtatttttt
    13501 ggaaaaatag aaggcagaaa gaaggtttat ctatgactaa attagatcaa attcgtttgt
    13561 accttaatca ggaaaaggct gagcttgcta tcttttctga ttctgtaacg atcaattact
    13621 taactggttt tttatgtgat cctcatgaaa ggcagatgtt cctatttgtc tatcatgaca
    13681 aggctcctgt tttgtttgta ccagctttag aggttgcaag ggctgaacaa ttgctggact
    13741 tccctgtttt tggctacgtt gactctgaaa atccttggga aaaaatcaag tctgtcctac
    13801 caagcacagc agcaaagacc atttacgctg agtttgatca tttgaacatt accaagtttc
    13861 aagggctgca gagtgtcttt tcaggacgct ttgacaatct aaccccttac attcaaagaa
    13921 tgcggctcat caagtctgct gacgaaattc aaaaaatgct gattgctgga gaatttgccg
    13981 ataaggctgt caatgtgggc tttgataata tttcacttga cgtcaccgag acagatatca
    14041 tcgctcaaat cgaatttgaa atgaaaaaac aaggcatcag caagatgagc tttgaaacga
    14101 tggttttaac tggtaacaac gctgcaaacc cacatggcat tccaggaacc aataaaatcg
    14161 aaaacaatgc cctgctgctc tttgaccttg gtgttgaaac attaggctat actagcgaca
    14221 tgacgcgtac agttgccgtt ggaaagccag accaatttaa gcttgatatt tatcagcttt
    14281 gcttagaggc tcagctaact gctcttgata tgattaagcc aggagtgact gcagctcagg
    14341 tagatgccgc tgctcgccaa gtgattgaaa aggctggcta tggcgactac ttcaatcaca
    14401 ggctcggcca tggtatcggt atggacgttc acgaatttcc atcaatcatg gctggcaatg
    14461 acctgattct tgaagaaggc atgtgcttct cagttgagcc tggtatctat atcccaggca
    14521 aggttggggt tcgtattgag gactgtggtc acgtaactaa agacggcttt gagctcttca
    14581 cccaaacacc aaaagaatta ctatactttg aagggtaata ggaggcttaa aaagcctgaa
    14641 acaaaatgtc tcagacccta atatctaaag caacagcact tggtctgtta cttttcatat
    14701 tacaggctat tttctcacaa ggaaaagtca aagcacccct tgatgggaaa tcagaggggc
    14761 aaaagctatt tgtactaagc tcaaaagcta atcaagagca cctgaccagc tctttatcct
    14821 ttaagtgata aatgcaatca taagactgtg cattatattt atgagctatc tcaaccatgg
    14881 tgcaggggag tgaatggagt aactcacgaa tctctctggc gctttctttg tctagggcag
    14941 ctgtgacctc atcagccagc aaaatcggtt ttagtatcag caagcagcgt gcaatttcca
    15001 gcttcatgat ttgcccgcca gagagatttt gcccatctag atggagatca agatctccgt
    15061 ttagctcatt ccaaagatga acctgctgta atatctcctt tagtcgctgg tccgaataat
    15121 cctgaaacag cgtgagatta tctcgcaagc ttccttcaaa tatgtaaggc ttttgatgta
    15181 tcaaagacac aacatcatag gaaggaaaat agcgttttcc attggcagct tcaaaataaa
    15241 tagttccaga ataatcctta tcctcaccac acaaaagagc aaataaagta gatttcccac
    15301 taccactggc tcctgttagc aaggttttgt gccctgctga aatatgacca tctatccctt
    15361 gaaaaataag cctatgatca aaatacttat ctaacctctt aaagtagata tcaagtgtaa
    15421 gatcatctgt aggggttaag gcttgatgtt ttgtctcttc ctccagagcc aatactctaa
    15481 ccatcttctc cttaacagca gttgcagact gtaaactcga agtagcttct aataattgct
    15541 gcaagggaga gacaagattc gtagaagctg ttatcatagc aatgagagtt gttagtgata
    15601 gacttgaata gctcatcacc aacagaccaa taataagagg actaaccaag ccaatccctt
    15661 ttaatggacc agtccaaaac attaccagat tgtgggtagt ataatagcta tattgcttgt
    15721 cttccatatg ctgaatcatt tctaacacat ggtgagcaaa agcttcgttg gcttgattac
    15781 tctgtatcgt gtctgccccc ttagtaaaat cggtgatact ggctaggctt ttctccctcg
    15841 cctgactaag ctctaagcct cgtgattgaa gtaagtgatt gaacacaaac tgtggaataa
    15901 tcatcaaaaa gccaccaata gtaaaggcaa taccaatata aatatcctgc aaaagaaggt
    15961 acaagacaga ggctaagata gataggccaa aaacaggata aatgaataag gggaccaaat
    16021 actcctgcca aaacatagga atatcttggg tcaaaaacga atttaaggct gaagtaaaat
    16081 agttgagctg tttatgataa aaatgatata aagccttctt tgcaataagg caattaaacg
    16141 ctctaaccat agaacgtgct aaaatgttat taagatacat gcacatataa ataaagacaa
    16201 aaaaagctac gcctccaaga ccaaaaagca ataccattcc tttattgttc atatcaattt
    16261 gccctgctat ctgaattaat actgataaca atagtccctg caaggaatag agcaaagcca
    16321 ataaactata caagcaaagc tgccattttg aaatgacttg taaaatactt ttcatatcaa
    16381 tcactcctca cctgaaacct aaatgtatcg ctctcttgga aagtataaac gaaacatcct
    16441 catacaccaa tcatttccac cacaaactag attcttgaat gttaaatcaa gctcttgatc
    16501 aaaatcatgt tctctgattt cttgaacaac cattggttct ctcctttcat tcttactatt
    16561 tctagtatat aatgggaaaa aatacgaaag gaaaaatttc ggaaatccgg atatgaatat
    16621 cagagagaaa tttaaagcaa ttcgtaaaca aagaagacta tccttaaaaa cgcttggtaa
    16681 aatagctggc tcagccacta gtatttctga cttcgaaaat ggaaaaacga acctttctaa
    16741 tgatgtttta ttgcagcttt taggctttat gattgttgaa ataaacgagc tattcgaatg
    16801 ggaggatttt cacgaaaagg aattggttga agccatcaag caaatcgaac tggcaataaa
    16861 atctaaacat attcctgctc tatctcagct acagcaggac tttcaaagct tatctaagac
    16921 aaaggaacag tacatttacc acatcatctc actgatccta accatcacca ttgcagaata
    16981 tcaaaacaaa gagatcgatc cacacatcat gtctgagcta acagactact tctttttctt
    17041 ggagtattgg actaaccttg atgtcggcct actaggaaac atcgtccact acatgacaac
    17101 agatgcccta atcttattga caaatgacat cttagagcat acgcctcaag tactccgaaa
    17161 taacctagat cgtattagga tcgatactgt attaaactgt cttactgtct tgattaatcg
    17221 taaagaggag aaggcaagca gaacacttct taaattatta tttaacaaac attatcctaa
    17281 ttactttgcc tttgaaaagc tctatttaca tgaattacaa gcagtctatg attttaactg
    17341 gaaagataaa gaacaggcgc ttgcagctca tcacgtcata ctggctacca tttcattact
    17401 atttacagct gatgaagcca aagaatggga cagcttcttt caagaaagta ctagctcttt
    17461 gtaatactcc agctcataca ctaaagaaaa gcaaggataa tcacataaaa actaatcaca
    17521 tcactttgcc ctgctagctg aattagcttg ggtcatctct tatgcccagc aaaacatcat
    17581 ctagtctcag ctttcttcca aagcttcttg tctctctggg cttgcaagct tttgatagct
    17641 taagaggcac aagcattaac aaaggctaac aaatgcctgt aaaaatatgc tatgataggg
    17701 gtaacaaaaa cctaggaggt gcttatgtca cacaaatcca ttcatcaaca gcttagaaat
    17761 gctttttcct ttcggacagc ggtacgcgtc tacaatgacc aaaaaatagc caaagaagac
    17821 ttagacctga ttttagatgc tgcctggctc agtccttcct ctatcggcct tgaggcctgg
    17881 cggtttgtcg ttttagaaaa cgaagctgtc aagcatgagc taaaggaggt ctcttgggga
    17941 gcagtttatc agtttgagac agctagtcat atgatccttt taatcagcga aaaaaacgcc
    18001 agatatgatg gcgcttctat caagcaaagc ttattgcgca gaggcattac tgacgagcaa
    18061 gccttggcca gtcgtctggc atgctacgaa gccttccaaa agcatgatat gaaaatagca
    18121 gatgatcctc gggctctctt tgactggact gccaagcaaa cctatatcgc gcttgctaat
    18181 atgatgacca ctgctgcttt tatggggatt gactcttgtc cgattgaggg ctttaactat
    18241 gacaaggtaa atgctatctt agcaaaacat gggattatca accctgatac cgagggtatc
    18301 tctagcatgc tgtctttagg ctatcgcctg cgcgatccca aacactcaca aaccagaaag
    18361 cccagagaag aggttatttc cttctttaac taagcccctt ttgccattgc tcccaaagaa
    18421 agtgcaaaga cagtcctttg ccttttcttt ttcataactg tcgaattatg gtacaatgtg
    18481 tcaaaagacc tatggaaagt gatgcctatg acattattat ctgtaattat cccctgcttc
    18541 aacgaagaag acacgattat tccttatctt gaagaaatga agcaaatcga agcggccatg
    18601 accagccaat tagcctttga atatcttttt attgatgatg gctctacaga tcaaaccctg
    18661 agcgtgctaa gagagcttgc ggggcgcttc tctaatgtgc attacctctc cttttcacga
    18721 cattttggca aggaagctgg actattagcc ggcctagaag aggcaaaagg aagctatatt
    18781 acggtgatgg acgttgacct ccaggaccca cccgagcttc tcccgctgat gtatagcaaa
    18841 ttacaggagg gctttgatgt ggttgccaca agaagacaga gccgacaagg agagcctgct
    18901 atccgttcct tttttgctag actcttctac agattagtca agcatgtctc caacaccgaa
    18961 atcgtcgatg gggtacgtga ttatcgttta atgacaagac aggtggtgga tagtatttta
    19021 gagttgggag aggtcaatcg cttttccaag gggatttttt cttgggttgg ctacaatact
    19081 gcctatatca gctttgacaa tcgtaagcgg cagtacggca aaaccagctg gaactttctt
    19141 gagcttttga actactcgat agacggcttt atcaattttt ctgagatgcc cttaaccatt
    19201 gctacctgga ctgggacact tagctttttg ctatctctgc tagccatttg ctttattgtt
    19261 atacgcaagc tgctttttgg tgatccggtt tcaggctggg caagcactgt atccattatg
    19321 ctatttatcg gtggaattca gctgttttgc atgggaatca ttggaaaata catttccaag
    19381 atcttccttg aaaccaagaa aagacccgtc tacatcatca aagaaaagaa ataacagagc
    19441 aatcatcaag gcccctatca gccgccaatg aggccgataa ggactggttg ccctcatcat
    19501 gacaagcacg acaaaaagac ttgatggtcc caatcaaaac catcaagtct tttttagtat
    19561 gtgaccttgc gtctgcctcg cacctaaaaa gacgagataa tgtcataacc accgtctatc
    19621 tactgacccc aaaaagttgg acaatttagt tttaagcaag ggatttagtt ctgtattgca
    19681 caggactaag caaggccatc agcttgtaaa cagacgctta gcggcggttc acactcttca
    19741 tcacacgccg aatgtcacga tcctgctcgc gtcgcttgat cgattcacgc ttgtcataat
    19801 catgctttcc tttggcaagg ccgattaaca ccttggcaaa gccatcctta agataaacct
    19861 ttagaggaat aagggtcatt cctgtgccct ttagctcatc tgctaggtgc tgaatctcac
    19921 gctttttgag caataatttg cgcgtgcgct ccggatcagc attccagata tttccctgct
    19981 caaagggagc aatatgaaca ttgaccaacc aggcctcacc attcttgatt tgggcaaagc
    20041 cgtccttgag ctggatacgc gcggcacgaa cactcttaat ctccgtaccg gtcaacacaa
    20101 ttccagcctc aactgtctca acgatatgat agtcatgacg agcctttttg tgttgcgcta
    20161 atacattacc ttcacctttt gccatgctta actcctttta cgacctttct ttttagcagc
    20221 tttttggtaa aatggtttct ttgctttttt tcttgtcttc tgctttgatt ttggctttga
    20281 gggcttggac tccttactcc tgctagccct tgaagcagcc ttttgcctgt gcttatgctt
    20341 agctttagct gaccttgtgg tcttttcaac cacatcatag tcactagcca agtaatcaaa
    20401 atcaatgtca cctgtttcct tgtcagccct caccaatcta acccgaatcg gctgacctgc
    20461 tctaaatacc tttcctgagc gttcaccctt taaggagagt gtccgttcat tatagtgata
    20521 atattcaggc aaattggtaa tatgcaccag accttcaatt gtatttggca attcgacaaa
    20581 catgccaaac ttaaccacac tagcaatcac gccatcaaac acatcaccaa tataatctgc
    20641 catgtattct gcttttttca tcgcctcaac cacacgctcc gcgtcaattg cacgacgctc
    20701 tagctgagat gacgatactg ccaattctgg aataacctgt gcaaaatgat ccaccttctc
    20761 ctgcgtgatc tgattgtatt ctcgaatcat gcggtgcacc agtaaatcag ggtaacgacg
    20821 aatcgggctg gtaaaatgcg tgtagtagtc tgctgctaag ccatagtgac catgattatg
    20881 ctcagaatac ctagcctgct gcatagagcg cagcagcatc atattcaaaa cctctgctcc
    20941 aggacttcct tctacctttg ccataaaggc ctgcaaggct tcttgagaaa tcttattagc
    21001 agttccctga atctgaatcc caaaggcact agcgtaatca ataaaggtct gcaatttctc
    21061 tgcctttggc tcctcatgaa cccggtaaat aaatggcaag ccagcccttg aaaaatgctc
    21121 agcaacacat tcatttgccg ctagcataaa ggactcaatc atgcgctctg caacacctcg
    21181 ctggcgcaag accacatcaa ccggcatgcc cttatcattg acaataatcc tagcctcctg
    21241 cgtgtcaaag ttcaaggccc cgcgcttcac acgcatcgcc tctaagatct gatgcagctc
    21301 aaccatagta ctcacatcat cagcaattct atcaaattcc ctaagcgcct cactgtcacc
    21361 tgcaatcatc tgattgaccg cgctgtaggt cattctaaag gttgtgttaa tcactgactg
    21421 acacagctga taatcaacca catgtccctg atgatcaatc tccatgatcg ctgactgggt
    21481 caaccggtca acctttggat tgagagagca gataccattt gacaaccgct ccggcagcat
    21541 tggcaccaca cgatctgtca cgtaaacaga ggtcccgcgc gcagctgcct cacgatccaa
    21601 ggctgaccct tccgtcacat agtaggacac atctgcgata tgaaccccaa gctcaacgtt
    21661 tccattggcc aatctcttga tatggatggc gtcatctagg tctttagcat cagcaccatc
    21721 aatagtgatg gtcgtttctt tgcgcaaatc aacacgcccc ataagatcct gatcactcgg
    21781 agcatctgga atggcattgg cctcagctag aacgtcatct ggaaacgccg atacaatatc
    21841 catagattcc aaaacctcca gcacatcaat gccgacatca tgctgatgcc caataatatc
    21901 acacacagtc cctacaaaat aatcctgccc agccttaggg tattgcacaa tatcagcctt
    21961 aatgatttca gtaccatcta aggcaattgg agattttgcg atataaatcc tctgttgaat
    22021 cctttgattt ttcgacttga tgtagccagc atacttaggg tgatcatcat ctaaaataac
    22081 cctaccaaca accgtcttta aagagcgctc cacgatagct accacgcgag cctctgctgc
    22141 tgtagcctta agccgattag ctggtttttt aataacagcc tcaaccctat cgccatcact
    22201 agcatacccc acatcatcac gaccaataaa aatgtcgtcc tcattgtcat caaccgacaa
    22261 aaagccaaag ccagccttat tggcacgaaa aataccttga acccttatct ctggcttttt
    22321 ttgctgtggt gctctaagaa acacctcacc ctcatctgaa aaagacaaaa gtcccttgcc
    22381 ttccattttg gaaatggctt taatcaggcg aggaaagctc ctcgcatcag tcatctctag
    22441 tgcagccgcc aaatcatgaa tatttgattg gccatgctcc tttaaataat tcgtaatgtt
    22501 ctctatcatc atacctatct tctatttcta acaccatact tgatggttgt gctcattgat
    22561 aaaaaaatga gctagactaa ctctgtcaag ctcactcctt atttacttga taaaatggca
    22621 agcactaacg caattcctaa ccaaaaaaac actagaactg ctgtaaaacg ttgcataaaa
    22681 gcttcaaatc cgcgagcttt tgtacgctca aacaaggctt ctgagccact gctatcaaaa
    22741 acattgctac taggattttt ttgtggctgc ataaagatag caatcacaag caacactgat
    22801 aatactagca atatcgtaag tagtaagtcg tacatgttaa ttcctccact gtagtctcaa
    22861 tcattctaac acaaaaccaa ctaagattca acatgcagcg ttacttttct ctccttagga
    22921 cagtatttag gaaccttaat cttctcaggg tgacttgttt tatttttact agtcaaataa
    22981 tttttgctgc cgcaatggct gcactccaaa tgaatcttta ctctcacatc atttccctaa
    23041 tcttactata ttttatcagc gtcataaggc ttcaaatcac ccgcagcttc tttattaaag
    23101 atatctctag ttattatagc atattatcca gtaagaaaac aaactcagga cttttagcaa
    23161 aaaaggctta agcgccaacc aataaacatt ccaaggctat cggggaatat tttctaatgg
    23221 ttattataaa tcatgaacaa ttacctaaca aagcaactcc aaaacaaaga taaaagacga
    23281 acattcacct tgctgctcag ctatcaagat aaacaatcct gatagcatca attttcttta
    23341 ggtcctcagc aatcggttgt aatatcagac aattcaggtg ttgattaaaa aaaacgaaac
    23401 tacggagacc aattgtcaga aagctattca cagcccgcag gcgtcgtgct aaagtattgt
    23461 ctggaaaaag aaaggtttag gaatgattat acctaaactc aaaggagaga aacaatgaga
    23521 aaaacaatga agaagatgct agcagcctcg acgctctgca tcatcatgtc aggcagcttc
    23581 atcagcggct cagctagagt gttggcggag aagtattatg gttttaatga tggcacagga
    23641 gagcattcac cattccctgt atacgttact ccaattacta aacctaatag gaatactgcc
    23701 aaagttgtct actgtttcaa taaagatatg aagtggccag aaacttggga taaagcagca
    23761 ccaaaaaaac cagataattt acctctatac tacgatatgg aaggtactga tcaattattc
    23821 agtacatatg caagtggaca acttactcct aatgtcagta aagtcttagc taatataatg
    23881 gctaaaggtt atccaaacaa caatgagttt gctcaccatt ttaaactcac tcccaattcc
    23941 gctgtaaaag ttactcaaat cgcagtttgg actgttacgg ataacctaaa aaactattct
    24001 caatacagtc taaccagaga agaggaagct gcattaaatt acctaactga caaaaatggg
    24061 gacgacttta gcgatagtat caagttaaaa ttatacattc cacaaaatcc tcgaactata
    24121 aaatatcaaa atcttctagg ttatgaccta atagttaaaa ctccagaaaa aaaagataat
    24181 tgtaaatgca ccaaaattta tatagaagat aatggaaaag atggctatta tctgtatatt
    24241 tattatgaca acaatgaaaa taatagatat gactcggaca aagatagcct attgcaaaag
    24301 aaatacataa aaaatgggaa agatgggaaa ccaggaagac caggggttcc aggacttcct
    24361 ggccctgctg gacctcaagg gcctagagga gacaaaggag aaaccgggga acgtggacct
    24421 aaaggtgaaa aaggtctaga cggtaagcct ggtgaaaagg gtcctaaagg cgatacagga
    24481 aaagatggta aggacggaca acccggacct cagggaccta agggtgaccc tggacgtgat
    24541 ggaaaagatg gcgaacctgg aaaacctggc gagcgcggtg agaaaggacc tcaaggcgaa
    24601 cgtggacctc aaggacttcc tgggcccaaa ggtgagcctg gaattccagg gcctaaggat
    24661 gaagatggaa aagatggtgc tcctggacat gacggacaac cggggcctaa aggtgaaaaa
    24721 ggggaccctg ggcaacaagg cattccagga cctaaagggg aacctggacg tgatggtaaa
    24781 gatggagaaa aaggcgagcg tggagagcaa ggacctcaag gcgaacgtgg agagcaagga
    24841 cctcaaggcg aacgcggaga gcaaggacct caaggcgaac gtggagagca aggacctcaa
    24901 ggcgaacgtg gagagcaagg acctcaaggc gaacgcgggg agcaaggacc tcaaggcgaa
    24961 cgtggggagc aaggacctca aggcgaacgc ggagagcaag gacctcaagg cgaacgcgga
    25021 gagcaaggac ctcaaggcga acgtggagag caaggacctc aaggcgaacg tggggagcaa
    25081 ggacctcgtg gagaaaatcc tactcctacc ccagatccaa tgccacaacc agaaccacaa
    25141 ccagaaccac aaccaatgcc tgatccagca cctaaaccag aatccaagcc agaacctaag
    25201 ccgatacctc aaccagaggt taagcctcag ccagagacaa aacctcaaca accaaacaag
    25261 ccatcaacca ttactagcca atctagcggc aaatcactgc caaaaacaaa tgacactggc
    25321 agcttgatca cagcatttgg tacaggctta ctcactcttc ttggactagg cttcctagca
    25381 aaacgcaaaa gaaagcaata attaaaacac tacccatagc cttttaatca ttggctatca
    25441 actagataac aaaaagctta tcgttttact cctaacgata ggctttttcg cattccctat
    25501 tgcttggtct caatactatt tttccagctt taggctggtt ttg
//
LOCUS       DARYMD010000031        25286 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYMD010000031 DARYMD010000000
VERSION     DARYMD010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25286
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(122..1381)
                     /locus_tag="TU818_001226"
     CDS             complement(122..1381)
                     /locus_tag="TU818_001226"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL0924046.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
                     DTISVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAVGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRTEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            complement(1697..2902)
                     /locus_tag="TU818_001227"
     CDS             complement(1697..2902)
                     /locus_tag="TU818_001227"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL0924047.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYRQTAAYGHMGRTDIDLPWEQLDKVSPLTE
                     AVAALSEGA"
     gene            complement(3235..5454)
                     /locus_tag="TU818_001228"
     CDS             complement(3235..5454)
                     /locus_tag="TU818_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0924048.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQPTNQPKTKQTAKKATK
                     KKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSAPSSPSGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRNSKWKHLIEQPKEEAPAKPQSDLEKTIALKKAYLA
                     KSLNIPEDSIRVEHTEEGIILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHANAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLIQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNNYLALEAINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAESG
                     QFPQGIIKNFKAAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            5981..6922
                     /locus_tag="TU818_001229"
     CDS             5981..6922
                     /locus_tag="TU818_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEL0924049.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDILLPELISQELNMPLSYHEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFSENLK
                     ERAGSLFSNKPSITRNALIIDIWKLFTTIPIKDHIKVYKEKSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(6897..7100)
                     /locus_tag="TU818_001230"
     CDS             complement(6897..7100)
                     /locus_tag="TU818_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HEL0924050.1"
                     /translation="MTIRQFMFMAFICAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(7481..9157)
                     /gene="dnaX"
                     /locus_tag="TU818_001231"
     CDS             complement(7481..9157)
                     /gene="dnaX"
                     /locus_tag="TU818_001231"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL0924051.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESEKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQPAICEHLAAILDKEGIAYEIEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNRVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSALFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQAADTAIPSSLLADVDDLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKESEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(9157..9654)
                     /locus_tag="TU818_001232"
     CDS             complement(9157..9654)
                     /locus_tag="TU818_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL0924052.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGESAQSGQTIIVDDVKKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLENTSFRFDM
                     FGVEN"
     gene            9834..10604
                     /locus_tag="TU818_001233"
     CDS             9834..10604
                     /locus_tag="TU818_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL0924053.1"
                     /translation="MLLVFNGIEYECLNLVSPKQTFYQSAALILSTSLLGIYLIPFSL
                     AIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWISLIKPNIALEEWTGA
                     LTGPFVEEPIKAFAAMLVIYLLPAINLKQKLVISLISGMGFQLTEDISYIASAADRSI
                     NDILPTTLARISSSPNSHWVYTGIFTMGAYLLIKKSQLFPRSLQIFWVVSPLALHFIW
                     NSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(10786..11058)
                     /locus_tag="TU818_001234"
     CDS             complement(10786..11058)
                     /locus_tag="TU818_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL0924054.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILMTLVLCYYLYQWYIL"
     gene            complement(11081..11707)
                     /gene="udk"
                     /locus_tag="TU818_001235"
     CDS             complement(11081..11707)
                     /gene="udk"
                     /locus_tag="TU818_001235"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL0924055.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            11803..12897
                     /locus_tag="TU818_001236"
     CDS             11803..12897
                     /locus_tag="TU818_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0924056.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHYAPRDHQMIYMSATNKIEQASLADHTLVIDLSKQALPCIEHCYMLVDKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFTKVTEMYLKHQQLYQKEIRG"
     gene            complement(13162..14448)
                     /locus_tag="TU818_001237"
     CDS             complement(13162..14448)
                     /locus_tag="TU818_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL0924057.1"
                     /translation="MKKLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTAS
                     KDSPKIKKVKYLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLE
                     ASHIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSRYHVKEDYSPFKLEELVAGRLDRIE
                     EEVGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILFGHMSIPLASLFDVINPDF
                     LEGSDKTAYEEYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTF
                     FMMGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACG
                     KRPVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVL
                     MHDIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
     gene            14870..16033
                     /locus_tag="TU818_001238"
     CDS             14870..16033
                     /locus_tag="TU818_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0924058.1"
                     /translation="MSQKLGKQLIRSVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWPLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEADYLHSKS
                     KIKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYSGISHDKGMEASSESEAEDITDESTPVAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(16156..18774)
                     /gene="alaS"
                     /locus_tag="TU818_001239"
     CDS             complement(16156..18774)
                     /gene="alaS"
                     /locus_tag="TU818_001239"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL0924059.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETVASRLSVIIVDNERSEMVSEGQALLVFDQTPFYAEMGGQVA
                     DHGVIKNDKGDLVARVIDVQKAPNGQPLHTVEVLASLALDTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKVIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDILKEIAHTLKVPQIEQLPSKVVSLS
                     EQLRDLQKEMAELKEKAAAAQAGDVFKKVQEANGLRYIASEVSVSDAGVLRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(19130..20131)
                     /gene="prsA"
                     /locus_tag="TU818_001240"
     CDS             complement(19130..20131)
                     /gene="prsA"
                     /locus_tag="TU818_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL0924060.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKRTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVTTLDNEET
                     AKAVLGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(20194..20901)
                     /locus_tag="TU818_001241"
     CDS             complement(20194..20901)
                     /locus_tag="TU818_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL0924061.1"
                     /translation="MVKSYSKNANHNMRRSIVKEDIVHYMRTQLKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENAPEAEIITIDRNA
                     EMIGFAKENFAKYDSRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(20984..21622)
                     /locus_tag="TU818_001242"
     CDS             complement(20984..21622)
                     /locus_tag="TU818_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL0924062.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLERDGVKAIAGAAQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDSKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVKQLKAVCELL"
     gene            complement(21672..22304)
                     /locus_tag="TU818_001243"
     CDS             complement(21672..22304)
                     /locus_tag="TU818_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL0924063.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALGLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKP
                     FIVTHKGRTTQAVLQRLGIADYFTEVITADCGFKRKPDPEALLFLIHHYQMDKSQTYY
                     IGDRPLDLAAARAAGISSINLLLPDSDDNHHISQLSDIVELFSGKNSSSN"
     gene            complement(22294..22851)
                     /locus_tag="TU818_001244"
     CDS             complement(22294..22851)
                     /locus_tag="TU818_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0924064.1"
                     /translation="MKEIRTIALADQAAFKRFQDILLAEKASGNTFVETKKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATIGGHIGYVTRT
                     DYRGRGIMTDLLAFALQQYQERGIKRVLITANKDNIASRKTIEKAGGILEDIVQVADD
                     YPTTSLAGQAIARYWIDLRGKDCDS"
     gene            complement(23050..24852)
                     /gene="pepF"
                     /locus_tag="TU818_001245"
     CDS             complement(23050..24852)
                     /gene="pepF"
                     /locus_tag="TU818_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL0924065.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKVYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMALSQEAYQAFLAETPELTVYDHFFDKLFKTREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLENVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNNLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFRVFEERLTELEDLVARGAHL"
     gene            complement(24842..>25286)
                     /locus_tag="TU818_001246"
     CDS             complement(24842..>25286)
                     /locus_tag="TU818_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL0924066.1"
                     /translation="MIHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQLQMD
                     KHLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSAGFCQIHE
                     DLSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMISNRNLGGPYDR"
BASE COUNT         7317 a         5880 c         4841 g         7248 t
ORIGIN      
        1 ggatagacag ggggttctta aaaatcaaaa gcccctaaaa ccactctcat accaagcagt
       61 cttaggagct ctaagcattc atgtcaggtg ataatcatta ggctatgaaa gccttcagtt
      121 cttaatcctc aataagctga atatcagccc ctaaggctgt tagcttatca ataatgttag
      181 catagccacg taaaataaac tcaatattgc taatctcggt tttaccctga gccattagac
      241 ctgcaatcac caaagcagca ccagcccgca aatcagttgc cttaacctgt gccccactga
      301 ggcgattaga gccatgataa acaatttggc tgccaagaat ggcaatatct gctcccatac
      361 gagcaagctc tggcacatgg ttgacacgct tttcatatat cgtatcaatg atactaccac
      421 gaccctcagt ccttaaaagc agaggagtca aaggctgctg taggtcagtg gcaaagcctg
      481 gatagggaga ggttttaata gtgactgctt tcaaggcttc ctgcttttcc acaaaaatag
      541 aatcctcttc aaccgtcatt ctcacaccca tttcctctag cttagcaata aagctctcta
      601 agtgctcgta aaggacattg gtaatcctta ccccactacc aacagcggct gccaaggcaa
      661 tataggtacc agcctcaatg cgatctggga tcacctgatg tctggtgcca tgaagccttt
      721 caactccctc aatcgtaatc acatcagtac ctgcaccacg aatatgcgcc cccatgttat
      781 ttaacagtgt cgcaacgtca ataatctcag gctctctagc tgcattttca ataatggtct
      841 taccctttgc ctttgtcgca gcaatcatag tattaatggt agcgcctaca ctgatagtat
      901 ccatgtagat atgagcgcca tgaagctgct gagcctctgt catcaggtgc atgcttgctc
      961 cctcataaga tatctgggcc cccattgctt caaaagcctt cagatgaaga tcaataggcc
     1021 tagggcctaa gtcacagcca cccggcaagc ccacaaccgc ctgcccaaag cgtcccaata
     1081 gactgccata aaaatagtaa gaggctctta ggctgttaat tttaccataa ggcataggaa
     1141 tatcttgaac ccctctgggg tcaatctcca aggtatcccc ctgataggtc accatagctc
     1201 ccatgagctt catgatttca ataagactgt caacatcact aatagctggt accccatcta
     1261 aagtgacaac atcgtctgcc aaaataatcg caggaatgag agctacaacg ctatttttag
     1321 cgcctgaaac tgccacctct ccggataagg cttttccacc attaataata atttttcgca
     1381 tactttcaaa actttctgat actagaattc aaccttttta ttttatcaca aatagcggtc
     1441 tattacaatc acctcatcac cagctgctgc aacaggctta acaacctgcc tcttgatcac
     1501 ttttcataac aggtttttga gaagccagac tcttatctgg atctttcttc tgctgcgcag
     1561 gcctttttgt ctttcatagc cgccaagcct gacaagtttt gctggactaa aaaagctccc
     1621 aaccagcagc acagccgcta gctcaggagc tattatacct ttaagtcaat catcaactaa
     1681 ccggcgctca atctgcttaa gcaccctctg acagtgctgc caccgcttct gtcaatggag
     1741 ataccttgtc caattgttcc caaggcaggt caatgtctgt tcgccccatg tgcccatagg
     1801 ctgctgtctg cctatagatt ggacgcttga gatcaagcat cttaatgatc cctgctgggc
     1861 gcaggtcaaa gacctgacga acagccgctt ccaaaatact ttctgacact gttgatgtcc
     1921 caaaggtatc cacacgaact gaaactggct gtgcaacccc gatagcatag gctaattgaa
     1981 cctctgcttt acttgcaagc cctgctgcca caaggttttt ggcaatataa cgagctgcat
     2041 aagaggctga gcggtcaacc ttagttgcgt ctttaccaga gaaggcacca ccaccatgac
     2101 gcgcatagcc accataggtg tcaacaatga tcttacgacc agtcaagcca gaatctccct
     2161 gaggaccacc aataacaaaa cgcccagtcg gattgataag gaatcttgtc ttctcatcta
     2221 gataatgggc tggaataaca gccttaatca cctgctcaat catatcttga cgaatctggt
     2281 cattgcttac ttctggatca tgctgggttg atataacaac tgtatcaaca cgaacaggct
     2341 tatcatgttc atcatattcg accgtaacct gtgatttagc gtctggacgc aaatagctga
     2401 tctcacctga ttttcgcagt gtcgccaaac ggcgtacaag ctggtgagat aaggaaatcg
     2461 gcagtggcat tagttctggt gtctcatcaa ttgcaaagcc aaacattagc ccctgatccc
     2521 cagcaccaat cgcattgaaa tcatcgcttt gtccttcacg tgcttcaagt gcttcattaa
     2581 cgccttgagc aatatctggt gactgctcaa ccagagatgg atgaacaccc actgattctg
     2641 ctgaaaagcc atattctgcc tcagtatagc caatctcagc gatggtatca cgaaccacac
     2701 gattaatatc cacataggca gttgttgaaa tttctccaaa aacgtggacc gagcctgtgt
     2761 aaacgcaggt ctctgcagca acgtgtgcct ctggatcctt ggctaaaata gcatctaaaa
     2821 tagcatctga aatttggtct gcaatcttat ctggatgccc ttcagatact gattcagacg
     2881 tgaaaagttt acgttctgac ataaaaatgt ccccccttaa aaagaatgat acccaccagc
     2941 acacatgcca gataggattt tcctagcctc actcatcaag ccagccgcca atacaaaagg
     3001 actgtatcca agctagccta tgactaacgc ttagcgagtt acaaagtacc ggcttttaga
     3061 ctgctatcct cagataacaa agccgtctta tcgggactta ataacttatc tattatacca
     3121 cttttagcgg gatttgtaag agctccatca gcttttttct caaaataaga aaaggaatac
     3181 cgctacaggc gtattcctcc tcttaatgtc gtgataatca gcgcaagcta tcgattaacc
     3241 atggtggtgc tcatcgtgat catgatgctc atggtcatgc ttatctgctg cctcttgatc
     3301 agtatcagcc ggcttatgct cgtcttcaac agcttctgct ggtgtggcat tatttagact
     3361 accaccctct gctgccttga agttcttgat aattccttgt gggaattgtc cgctttcagc
     3421 agctagctcc tcagctggga agtggttacc atcagcctga atgtatttca gggtttggtt
     3481 aggctccttc aaggccaagg tgttaatctt gttacgatta acattaattg cttctagggc
     3541 gagataattg ttgacaccct caaaattagt cagctggttc tcttcaaggt taagagactg
     3601 taatgagctt tgtgtacctg gtaaggccaa gctattaatc atgttctggt tagctgatag
     3661 ctgaatcagg ctcttattgt gctcaagacc tgtcaagctg ttaagcttgt tttggtcaac
     3721 cactagctgc tctaatgccg gtagatcctt gacaaagcta aggctttgta aattaacctc
     3781 cttggcagtg atttccttga gagcagagga ttttaaggtt gacaaatcaa ggtcagggtt
     3841 gtttgacaca aagagtttgg tcaattgtcc cttgtttgac aaggcactca agtccttaat
     3901 ctgattgtgc tctaggctga cagcgactag cttttgagca tttgccaagg cagaaagatc
     3961 tgtaatcttg ttaaagtcaa ggttaacgga ctctaggttt ggcaattctt tcaaaataga
     4021 aatatctgtg atatcatttc ctgctgccga aattaccttg taatgcggaa aggctttaag
     4081 gaagctcaaa tcagaaacac cattttgaga aatatcaatt ccttcaagcg ttggcaggtt
     4141 cttcaagaaa tcataatttt taatgccggt ctgtgtcatc cacaattgtt tgaggttctt
     4201 gaactggtag actggggtaa tatcagtgat tggggtaaag ccaataccta aaatctgtat
     4261 attaggcatc aggtttaaac ctgcccgctt aagaggatcc ttaatctcac cgatattgag
     4321 gtattcaaca gtcgccaacc atgccttcat tttctctagg tctcgctctc ttgatggaaa
     4381 ctcagttggt gcatttgcat ggataatgga cgaaatcact tcctcatcaa agccaagctt
     4441 tctcagagtt gccataccga ttctatcctt agcatgcgga tctactgcat gaggatcaaa
     4501 aggttttgat aaatcaatat cgtcaatata ggttgcatga cgatggtcac catgtggata
     4561 gtcaagaatg ataccttctt ctgtatgctc cacacgaatg ctgtcctcag gaatatttaa
     4621 tgacttagcc aaatatgctt ttttcaaagc aatcgttttc tcaagatcac tttgtggctt
     4681 agctggtgct tcttcctttg gctgttcgat taaatgcttc cacttgctgt tacgcaagct
     4741 ttcataagtg actaaatgat tgtggccatt gtgatcaaca atcaatccat atgatgttcg
     4801 accgacaata cctgtcccgt caaacaagaa gccatcactt gttgggtaat caacacctgc
     4861 aaattttcca gacggtgatg atggagctga tagtggcaca tggttaggca ctggataagc
     4921 tacctgacca cctagtgagc tttttaggat atagtggtaa tgatcaccat gacggacaat
     4981 atagcccaag gcgtcctcag ctacaatatc agctgggtta aacacatagt gatggtgcgg
     5041 gtcattagca ctagtatggt gatgacctga tgctgccttg gtctgctcag gcttgtttag
     5101 gtcagcgtcc tttggaatca ggtactcaaa cttgctgccc ttgagatctg cataaaaaat
     5161 aaaatgcgaa tgcccattat gctcaacaac aataccgttt tctgttctag ataagatttt
     5221 tgaatccttg gtcaagataa aaccgtcatc agttggaaag tcaatccccg ctactccctt
     5281 acggtctttt cttgtttgct taaccttttt agactgtttc tttttggtcg cttttttagc
     5341 tgtctgtttt gtcttaggct gatttgttgg ctgctttgtc gactgacaag ctgtcagggt
     5401 caggtgacaa gccataaaca ggctagccat tagcattaat tttttacttt tcatctttcc
     5461 tccataaatt aactggttaa ataagatatt aactagttaa atataccaaa aaaacaaata
     5521 atttcaactg ttttcttatt tttaattcat tctcattcaa caatcatagt agcttggcta
     5581 ggttggcaga aaaatgagcc tctcctactc tcatcaaata aacagatagc cttaatgatg
     5641 gctgagataa cagcatacaa agtcgttaaa gtcacttgta agaaaaagaa ggacatatct
     5701 taccaccact atcttgctca tcaaagccct acggctttca gacaaaatct tcataacagc
     5761 ggaaaggctg atgaagcagc tcagacaaaa agagcaagct ccttaacgtc aaggatcaga
     5821 gatcagcaca aaaataacag caggctacat taagaactgc aattccttga aatagaattg
     5881 cttttttaca aaaaaatcgt ctccctagac tgttccatca tctcacgtca tttgtattat
     5941 ttgctcttga aatccagtca ttttatacta tactagaatt atgaagacat ctgaaaaaat
     6001 ttaccaatta ctagcttgca gcgacgacta tgtcagtgga gaatacttgg cagagcagct
     6061 caagctttct agaacctctg tctggaaatc catcaaaagc cttgaaagtc aaggccttca
     6121 cattgaatcc ctcaagcata agggctatcg ccttattcaa ggagatatat tgctgccaga
     6181 gctcatcagc caagagctca acatgccttt atcttatcat gagaaaagcc agtcaacaca
     6241 gctagacgcc aagcaaggaa tcgagctaaa gcatactgct cctaggctct atctcgctcc
     6301 aagtcagtat gcggccaagg ggcggcttaa tcgccaattc tttgcgtcac ctcatggcgg
     6361 catttacatg tccttgcatc tcaagccaaa tgttccttac gcagacatgc ctccttacac
     6421 catgatggtg gcctctagta ttgttaaggc tatttcaaga ttgaccggta ttgacaccca
     6481 aatcaaatgg gtcaatgata tttaccttgg ccataaaaaa atcgccggta tcctgactga
     6541 ggccattacc tctgtggaaa caggcgtcat tactgatgtg attattggcg tagggcttaa
     6601 cttttttgta accgaatttt ctgaaaacct caaagaacga gcaggctctc tttttagcaa
     6661 caagcctagt attactcgaa atgccctaat cattgacatt tggaagctct ttaccacaat
     6721 accaatcaag gaccatatta aggtctacaa agaaaaatca cttgtccttc aaaaacaagt
     6781 gagcttccaa gaaaatgatc gtcaaaaaac agcaactgcc attgacctga ctgatgaagg
     6841 acacctcatc gttcaattag acaatggtca gctacaggtc ttaaggagcg gcgaaattag
     6901 tctttcttcc tggggggatt aacagcatta atgatgtttt tggtaaattg gtcaatagca
     6961 taagcacgcc ttaaatctct aaagagcaaa agaccccaaa acagagcaaa aatataatcg
     7021 cctgaaaata ataaatcgct gaaaaaataa gcttcaaagg cacaaatgaa tgccataaac
     7081 ataaattgtc gaatagtcat actactatta taccaagaaa actaaatttc cactaacgat
     7141 tttcacgcag cttgaagaaa aaggcagtta gcctgcttca agcttttttg ctgctctttg
     7201 atagcctgta acagtcaaat aaaaaagagc tcactctaaa aacgacgcca aaagccagct
     7261 tgattgctag gcttgtagtc aattgtctca aatcagtgaa tcactaagcc ttataagaac
     7321 tcagtcattg ggtcacaatg acacctagct ctaagcagca aaaaagagaa ccacaccggt
     7381 cctctctagc ttggcttgtc agctatctat tagtgctgac aatgagccct gtcatctcct
     7441 tattctagac aattgataca ctaccaatca tcagctagcg ctaatcctct atgagatgaa
     7501 tcttatcagt taaaaagtca aacccctcag gcatgtcaaa ggtcgcttgc tcagactctt
     7561 tggctgtctc ttttttggtt ttgatggtca tggcaaactc cgagcgaata tggtggaagt
     7621 ctgcctttgg tactgccaag atatgaggag aaaaccctgc tgccttactc atgatattcc
     7681 caaacatatc attcaaatcc tgacgcttca tggcctgctc agcgttaaag gcggcctcaa
     7741 aggccaaaat agcattttca ctattggcta aaacaggctc cgagcctagt aacaaagctc
     7801 gatcctgtgc agaaatacta tctaaaatct cattccaagc actttttagc gcttctaaat
     7861 attgtcgtga ctgctggcta tcttgaacag tttcctccat gattttcaat atcttttccc
     7921 gatcaacctt gtaggtaaag gcctttggct tgatggaatg agctggtgta gcctgcgcag
     7981 ttagaccctt ttgagcctgt agctgtgata tcgtctccct cagctgacta atctcatgct
     8041 tcaagtcatc aacatcagct agcaggctag acggtatcgc agtgtctgct gcttgtcctt
     8101 gctctgccag ctgaatggtc atcatttcag cgtagattct aggatgggtt ccttttttga
     8161 tctcaggcaa atgcttggtt actgtagcaa tcattgtaaa aagctgatca aaagacactg
     8221 caaggttatc atcaaaaaga gctgactgcc tgtgatgatc accacctgat ttcacaatga
     8281 gcaggtctct aaaataggtt agcagatccg ttgcaaagcg actcatgctc ttgccactat
     8341 cataaattgt ttctagatta gctaaggcct gacttgtttt ttgcctgatg agatgctgaa
     8401 cgtagtcgtc taaggccgaa atagaaatag agcctgtgat ttcttctgca atagcaagcg
     8461 tcactcgatt gtcaaaggat aggctcaagg cctgatctaa aatggatagg gcatcacgca
     8521 tgccaccttc tgctcgtctt gcaattaaat gaagcgcctc tatttcatag gctatgccct
     8581 ccttgtccag tatcgccgcc aaatgctcac aaatagctgg ctgcttaatg gctttaaatt
     8641 caaatcgctg gactctagac aaaatagtag ctggaatctt gtgtagttct gttgtggcta
     8701 ggataaaaac cacattgtca ctcggctctt caagggtctt taggagcgca ttgaaggccc
     8761 ctgttgatag catatgcacc tcatcaataa tataaacctt gtaggttgcc cggctaggag
     8821 cataggttga cttatctcga atatcgcgaa tttcatcaac accattatta gaggcagcat
     8881 caatttcaat cacgtcctcc aggctgccag ttgtaatatc tcggcaaata tcacaatgat
     8941 tgcagggctc tcccttgacc tgattagggc agttcattgc cttagcaaaa attttggctg
     9001 cgctggtttt accagttcct cttggacctg aaaagaggta agcatggctt atcttttctg
     9061 actcaacagc ctgctttaag gtggtcgaaa taactgactg cccaaccatt tcagcaaagg
     9121 tctggctacg atacttccgg taaagggctt gatacattaa ttctcaactc caaacatgtc
     9181 aaaacgaaaa gatgtatttt ctagtaataa ggctacaaat tgctctaaat agtcttgatc
     9241 tatctgatca taatcagcaa caagactgga atccaaatcc agaacaccaa caagcctgcc
     9301 agccttaagc attggcacaa caatctcgct catggctgct gaatcacagg aaatgtaatt
     9361 agcatgcttt ttgacatcat caacgatgat ggtttgacca gattgagctg attctccaca
     9421 tactcccttg ccaagcttga tatgcacaca ggaaaccttt ccctgaaagg gaccaaggat
     9481 caattcttga ccatcaaaaa ggtaaaagcc tgcaaaaaca gaatgaggca gggtcatttt
     9541 taagagggca ctagcattag agagattggc caaggcattg ctttcattag aaaataaggc
     9601 tttagcttga gccaataata gctgataatg ttcaattttt gtcgtcttat tcatggttct
     9661 tattataaca tatctgctac taatcgttaa acgatttcca caggaaaaga attttaatca
     9721 gcctctctag aaaagaaaga gattttatga taaaatagtg agtaatatta aaaaaatagg
     9781 agagtcagat gccgttgttg agatataaaa agattatcgc tacgacctta tttatgttat
     9841 tagtgtttaa tggtattgag tatgaatgtc taaaccttgt cagtcccaaa caaacctttt
     9901 accaatccgc tgccttaatc ctctcaacca gcctactagg gatctatctg attccctttt
     9961 cactggctat tgcttatctc aagcgcatct accagataag gatctcaacc ctgctattag
    10021 ctgggctagg cggtctttat attagtggct ttttagcctc ctttggcaat caggttttag
    10081 agcaattttg gattagcctg ataaagccca atattgcctt agaggagtgg acgggagctt
    10141 tgacagggcc ttttgtggaa gagcctatta aggcctttgc agctatgctt gtcatttatt
    10201 tgctgccagc tattaatctt aagcaaaaat tagtcatcag tctcatttct ggcatgggat
    10261 tccagctgac tgaggacatt agctatattg caagtgcggc tgatcggtcc ataaatgaca
    10321 ttttgcctac aacgcttgcc aggattagca gctcaccaaa ctctcattgg gtctatactg
    10381 gtatttttac aatgggagca taccttttaa ttaaaaaatc tcaattattc ccaaggtctc
    10441 tgcagatttt ctgggtggta agtcctctag ccctacattt tatatggaac tctcctatct
    10501 cagatttagc tggtgtcgca gttattcatg gaacaataac aacccttatc tttatcagtc
    10561 tattcaaaaa aatccatgcc ctagacgaca gcatcgccta ctagcgtcat aggacacgag
    10621 caaccaagcc cagccgcatt tgggcatgtg atggctcata tgcatatata gctactcacc
    10681 tctcgcttaa gctataggca gctaaatacc tatcacaata gcagaaaaaa tgactaccag
    10741 tcttaaaagg gctagtagtc attttaagct aaaaacaagc acttcttaca ggatatacca
    10801 ctgatacaga taatagcaaa gcacaagggt catcagtatc cccatatacc atgaaaggac
    10861 aaaataccat ttcttcgttt tatggttaaa ataatgccca gctagatagg ctccaatccc
    10921 accacataag agtgacaacg ttaatagcat tttctcagaa agtcgccatt gacctttttg
    10981 ggctctgtgt ttatcactgc cataggccgc aaagaccaca gcattccaac caaaaagcaa
    11041 gattaggctt ggtagcattt gtctgtctcc aatcacagca ctacagctca cctaagatgc
    11101 tggcaatctt tgtgttgatg agatcaatag caaccacatt gctaacccct tctggaatga
    11161 caatatcagc atagcgctta cttggctcaa taaattgatg atacatcggc ttgacaacgc
    11221 ttgtgtactg ctcaataatg ctctcaaggc ttctgccacg ctcaaccata tcacgctgaa
    11281 tacgacggat aatccgaatg tcatcatctg tatcaacaaa aagcttgata tccatcagct
    11341 cacgcaaacg ctcgtcctct aataccagaa tcccctcaac aataatgacg tcctgaggct
    11401 cttggcgaaa agttctgttg ctgcgagtat gctccttata atcatagatt ggaatatcaa
    11461 caggccggcc agccaagagt tcctttagct gctgaatcat gaaatccgta tcaaaggcta
    11521 acgggtgatc ataattagtc ttaacccttt cctcaaagct gatatgtgat tgatccttgt
    11581 aatacgaatc atgctgaatc atcgcaattc tcgcatttgg aaagctattt aaaatggcac
    11641 gagacacgct agtcttacca ccaccagaac caccagtcac accaataata atgggttttt
    11701 taagcattgt aaactccaaa tctaaaagtc tttcggtcta ttttaccaaa tttgccacta
    11761 taatgctata atgaagagaa aacaaaataa aaggatagat atatgataac caaccttccc
    11821 actcaatggc aggaaaagct ggcaaagctt ggctttacta atctcacccc aatccaagag
    11881 caggtctttc agcccattgt tgatggcaaa agcctattag gcattagccc caccggaaca
    11941 ggcaaaactc tggcctattt atggccaagc cttctcaggc taagccctaa aaaagcccag
    12001 cagttgctga ttttagcacc taatactgag ctagctggac agctttttga ggttaccaag
    12061 gaatgggcag agcccttagg attaactgcg cagctcttta tttccggaag cagccaaaaa
    12121 cgccagatcg aacgcctcaa aaaaggccca gaaatcatta tcggaacacc gggacgcatt
    12181 tttgaattag taaggcttaa aaaaatcaaa atgatggcca tcaataccat cattttagat
    12241 gaatacgacg acctactgag tgactcccaa taccagtttg tccaaaaact ctcccattac
    12301 gcgcctcgtg accatcaaat gatctacatg agtgctacta acaagataga gcaagccagt
    12361 ctagcggatc ataccttggt cattgatctg tctaagcaag cattgccttg cattgagcac
    12421 tgctacatgc tggttgacaa aaggcatcgg accgatatcc tacgtaagct agcaaatatt
    12481 cctgactttc gtggtctggt cttttttaac agcctgtcag acctaggtgc tactgaagaa
    12541 cgcctgcaat atagtggagc ttctgttgct tctctagcca gtgatgtgaa tgtcaagcag
    12601 cgaaaggcca ttttagaagc ctttaaagag cagagcattt cactgctgct tgcgacggac
    12661 atagtcgctc gtgggattga tattgaccag ctagaatacg tcattaacgc tgaggttccc
    12721 cgtaataaag agcaatatac tcatagagct gggcgaaccg gtcgtatggg acgatcaggg
    12781 attgtcataa ctcttgtcag tcaccctgaa gacatcaagc gccttaaaaa atttaccaag
    12841 gtcactgaga tgtacttgaa gcatcagcaa ttataccaaa aagaaataag aggctagctc
    12901 aaaggatata aacctaaaaa gcttgcctcc aagtatgatg taaagcaact aatcactatt
    12961 tcttaccctt gctactaaaa aaacgaacgt aaagtccttc tgacatgaag tcaaaacctt
    13021 acgttcgttt tatattatac tgacaccact ggctttatta gtatagtaga tactggccat
    13081 gcttagccag actagatact ttcttgaagt gagcccgcca tttagtcatg ctctagagcc
    13141 ttacttgctt tttctgactg actagcggct accatatagc tcagataagg tcacacattt
    13201 gtatccttcc gcttttaggt attccataat acttggcaag gcatctacac tggtctggtg
    13261 aatatcgtgc attagaacaa cccctccagg ctgcaattgc tgcttgacat ttgccatgat
    13321 agcagcagta ttacgatttt cccaatctct ggtatcaact gtccaaagca tttccttaag
    13381 acccgatgcc cttctaacaa tatcattagt agctccataa ggaggacgaa gatagactgg
    13441 gcgttttcca caggcctttt cgatggcttg attggtcgta ttgatctgtg tttggatctg
    13501 atcaacggtt agggtcgtca aatcagggtg atcccaagaa tgattctcaa catcatgacc
    13561 agcagcacta accttcttaa ccaaagcctc atggccaaca accttagacc ccatcataaa
    13621 aaaggtcccc ttggcctgat atttggccaa aatatctaaa acctgcggtg tggtcacagg
    13681 gtctggacca tcatcaaagg tcagagcgac tagcttttgt ccctcttttt ctgcctcttt
    13741 tgccttcttt tcctccaaat actcttcata agcagtcttg tctgaaccct ctagaaaatc
    13801 tggattaatc acatcaaaca ggcttgcaag aggtattgac atatgaccaa ataaaataag
    13861 attacccgaa tcaatggcaa agccatcgct taatacctga tttttttcta tcatcgtatc
    13921 agtgctcagc ttgatctctt tgcctggata aagcttgcca acctcttcct cgatgcgatc
    13981 taagcgacca gcaactagct cctctagctt aaaggggcta taatcctctt tcacatggta
    14041 acgactaaca gccttttctg tagtcttttt tagaccaaat aactgaggct tgtagaccgt
    14101 cttgtagata accaattgat tgacctgctt gatatgtgaa gcctcaagct taggctttac
    14161 catgataaca gccttgtcag tctgcttgcc ttgatacaga gacataggca gatttgacac
    14221 ataaaaatcg tcagccttct caatcggaga caggtaatac caatcctgct ttcctttctt
    14281 gagatacttg acctttttga tctttggact atccttagaa gcagtctgtt cgagcttaat
    14341 gactctctga gtatcctgcc ctattttcca agatctaatg aaggtaaacg caacaccgac
    14401 caacaataaa cttaataaaa taatgagaat ataatttagc tttttcaatc tcgtcctcca
    14461 attaccctac aattttaaca caagatagtt ggaaaataaa taaaaaaagt taggtttcct
    14521 taactttttt cagtccaaaa taagggcaaa aaagtgtttt atggtgcagg atttgcctga
    14581 gttattttcc ctttatcaca gccatttgtc actggataag gggctagata ttatacctaa
    14641 agcttctctt tattgctatc attattctga cattcttagg catgctattt cccttgatag
    14701 gacttgattg ctgtttcttt agcttgtaag gatctcctaa aaatgagagt atttttaagc
    14761 ctataattta tatattcgaa aaattttgac aaaaatgagg aaaaatattg atttatttag
    14821 ctttagtgat aaaatgaggg tgaaaaatta aataaaggag gacattgata tgtctcagaa
    14881 gttgggaaaa caacttattc gctctgttgt tactgcctta gccgccatag catttggaat
    14941 atttcctgca agcgagacga ctaatcatat cacctatgca gaggttaact ccttaacccc
    15001 ttcggtagaa tggcctttag agcagtatcc taattactat agcatagaag gaaagtctaa
    15061 tatcaacacc aaggattttc ctaagctata caccactacc gaaaaggttt acaaaaaaag
    15121 tggtcgaagc actaagcgcg ttactgtttc tgatctgcaa tacgctgcac ttgatggcta
    15181 tggccgttca ggagctgcct atggtattat cacaaaggat atgatcgcga tgtcagccgg
    15241 ataccgcgaa aaatgggaaa gcaatcctga gccaagcggc tggtatacat atcatttcaa
    15301 agaaactggc aagctagcta ctgaggccga ctaccttcac agcaaaagca agatcaaacg
    15361 aacctcaaac aatagctatg aaagcatcgt ccttagcaac ggtaagattc gcaacggcta
    15421 tctttttgat cgtagtcatt taattgctga cagcttaggt ggtcgtcctt ttagaaataa
    15481 tctcatcaca ggtacacgta ctcaaaacgt tggcaacaac gaccgcaagg ggggtatgca
    15541 gtacattgaa aacaaagtcc taaactatat taaccacaac cctcaggttc acgtttatta
    15601 caaagccgta ccaatctact caggctctga attactccct agggccgttg tggtttcagc
    15661 gctctcctct gatggtaaaa ttgatgaaac cgtaagagtc tttaacactg tcaatggctt
    15721 taccatcaat taccaatata gcggcatcag ccatgataag ggcatggagg cttctagtga
    15781 gtcagaagct gaggatatta cagacgaaag cactccagta gctgaaccag ctgatgagga
    15841 ggctatggag acagaggctg ctgctaacga cacaatagtc tatgttacaa gtaatggcca
    15901 atcaaaggta tactggtata ataaggacca tctgccagag aaggtcaatc tcaataaggt
    15961 tgtagaaatg accgagcagg aagccctaaa tcgaggaaag caccattcct ccttagaaaa
    16021 aataaatcaa tagtctcata acgactaaca caagagctgg ttgaagcaac cagctttttt
    16081 tgtgtgatga aggattagac agctccttag ctaaaagata aagaggctga taaagcactc
    16141 aacctcttat cgcttttata aatgctctgg tactgcggct aatagctctg atagcttgct
    16201 tgcatcacta ccacctgcca tcgccatatc tggcttaccg ccaccacgac ccgacacgat
    16261 tggcgctaag gccttaatca gattgccagc gtgagctctt ttatccttac ttgcaacaag
    16321 aacattgacc ttctcaccaa tgcttgcagc cagcacaagg acatctgaat aatctctttg
    16381 cttccaatta tcagcaaagg tacgcaagac tcctgcatct gatacggata cctcactagc
    16441 aatgtaacgt agaccgtttg cttcctggac ctttttaaag acatcaccag cctgagctgc
    16501 tgctgctttt tcttttagct ctgccatttc tttttgcaaa tcgcggagct gctcgctgag
    16561 gctcacaacc ttacttggaa gctgttctat ttgcggcacc ttaagcgtat gtgcaatttc
    16621 ttttaggatg tcttcttgct tgcggaagct ttcaaaggcc tgctgacctg tcactgctat
    16681 gatacgacgt gttcctgagc cgatcccctc ttccttgata atcttgaaaa gaccaatttc
    16741 tgatgagttg gacaagtgag tccctccaca aagctcaaca gaataatcgc caatctgaac
    16801 aacacgaaca gttttgccat atttttcacc aaagagggcc atagctccca tagcctttgc
    16861 tgtttcaata tcagtttctg tggttgtaat agctaatgcc ttccagattt gctcattgac
    16921 ctcttcttca atacgacgca gctcctgggc tgtaacggct tcaaagtgtg taaagtcaaa
    16981 gcgtaaaaag gcttcttcat ttaaggaacc tgcctgagtg gcatgttctc caataacctt
    17041 gtgaagggca gcatgaagca gatgagtagc ggtatggttt ttctcaacag catagcggcg
    17101 cttgtgatca atagcaagag tataaacagt gtctaatgca aggcttgcaa gaacctcaac
    17161 agtgtgaaga ggctgaccat tcggtgcttt ttgcacatct atcacacgag caacaaggtc
    17221 acccttatca tttttgataa ccccatgatc ggcaacctga ccacccattt cagcataaaa
    17281 cggtgtctga tcaaacacaa gcaaggcctg tccttctgaa accatctcac tacgctcatt
    17341 atcaacgatg ataactgata agcgagaggc aacagtctct gtttcgtaca aaaattctga
    17401 tggctctgtg atgcctgcca gtgtctcatt ttgcatgccc attgagccac ccttaacagc
    17461 tgctgcacgg gcacgatcct gctgctcctt catagctgcc ttgaagcctt catgatcaat
    17521 cttatagcca gcatcttctg ctaattcttc ggtcaattca actggaaagc cataggtatc
    17581 atacagctta aagatatcct tgccatcaag cctgtcttgc cccttttcct ttagctgcgc
    17641 cagcaattga tccaaatgcc ctgatcctgc atcaatggta cgtgcaaagg tttcctcctc
    17701 acgcttgata attttttcaa taaagtcacg cttctcaaga atctctggat aataggactc
    17761 catgatatga cctacagtag ctactagctt ataaaggaag gtctcatgaa taccgagcct
    17821 acgaccatgc ataacagcac gacgaagcaa gcgacgaagc acatagccac gaccttcatt
    17881 accaggtagg gcaccatctc caatcgcaaa tgacaaggca cgaatgtggt ctgcaatgac
    17941 cttaaagctc atgttgtcac catcttggtc gtaagtatgg ccagatagct tttccacttc
    18001 cttgatgatc ggcataaata ggtcggtttc aaagtttgtt tttgcgccct gcataacagc
    18061 cacaagacgc tctaagccag cacccgtatc aatgtttttg tttggaagct ccttgtactc
    18121 tgagcgagga attgtagggt ctgcgttaaa ttgagacaaa acaatattcc aaatttcaat
    18181 ataacggtcg ttttcaatgt cctcttccag caatctaatc ccaatatgat caggatcata
    18241 agcctcacca cgatcaaaga aaatctctgt atcaggtcct gacgggcctg caccaatctc
    18301 ccaaaaattt tcctctaatg gaatcaaatg gcttggctca acgcccagag caatccaacg
    18361 attgtaagag tccttgtcat ctgggtagta ggtcatgtat aatttttcct ttggaaaatc
    18421 gaaccattcc ggacttgtta acaattcaaa gccccactca atcgcttcgt cgcgaaaata
    18481 atctccgata gaaaaattac caagcatttc aaacatagta tggtgacgag ctgtcttacc
    18541 aacattttca atatcgttag tgcggattga cttttgagcg ttggtaatac gaggattttc
    18601 aggaatgact gacccatcaa aatatttttt gagggtggcc acaccagagt taatccaaag
    18661 cagggttggg tcattgactg gcacaagatt ggccgaaggc tcaatagagt gaccttttga
    18721 tttccaaaaa tcaagccaca tttggcggat ttgggctgat gttaactgtt tcatgattaa
    18781 gataccaaga gcgattagag agactgggta tgattgtcct tagcataagt agcctgggga
    18841 gacgatctct actcgcattc agttcctttc gttgattttt tatgggatta ggctaaaagc
    18901 catcaaaaca aaacaagccc atatcacaga gggcgaaaac cgcggtacca cctctattca
    18961 atgagcttgt cattcttaat tacttatatc agataaaatc acattaagca gcatgcctat
    19021 cagattatcc gtaactcaca gcaaccgtca cttctctggg tcaaatcctt gataaacaat
    19081 tcttaactaa accagtataa agcttttttg agcattcgtc aatgaaaatc tatttttctg
    19141 acttagattt agaagattga ctatccttgc ttgagtctga agatgatttc tgatctgact
    19201 tgcttgtgtt cgccttgctt gcttttttat cagtattggc atactgtgcc aagatattag
    19261 caaatgcttg gtctttgatc ttaacatttg ccttgtctaa ggcctttgca atgaccttat
    19321 tttggaaatc aatgttttgt gtcttttcag ccaagacaat ttcttttaga cgtttcttat
    19381 atttcttcca atcagaagcc ttttcggctt ttttggttac cttaacaata tagaacttgt
    19441 tttgataagt agccggatct aagacagaaa ccacctctga aatatcaccc tcttttaatc
    19501 ctgaggcggc cttgatcaca tctgctggta acttagtgtc tcctgagtca aacttatagt
    19561 ctaccttctt gtctgctgct gttgtctttt ccttagcaat agcagcaaag tcagcaccct
    19621 cagccttaac ctcacctaaa acagcctttg ctgtttcttc attgtctaga gtagtgacct
    19681 gagtagtcat ttctggtgtg tatgactcat aggctttttt gtaatcagca tctgtcagct
    19741 cttttttagc tgcttcttta acagcatatt caaccagcat ggctgagcga atttgacgct
    19801 tgtaggtatc tgttgtcaag ccagactgcg caagggctgc agagaatgac gcaccgtatt
    19861 gctcagctga tttattgtaa gcttcttccg ttcttttctt agaaaccttt ttaccgtatt
    19921 ggtcctcaaa aacacgacta accacaaggt ttagcattgc tctttgagaa atctctgtat
    19981 tttttgtttc attgtaaaaa tcactaacac tgatagtgtc gcccttcatc gtaatgacac
    20041 ttgtattgtc atttgtagac tgacaggctg ctagggtcat tgctgatgct agggttacga
    20101 taccagcaag taatttagtt gattttttca tgtgattttg tgctcctttt tgtcattaac
    20161 cagtatatta tatcacaatt tcttaaacgt aacttaatct aacaaacgaa tatctgcttg
    20221 atttttacga atcatcagca agccatcact aagcggcagc aggctggctg tcaatccagg
    20281 attatcaaga gttgctgcaa ataagtcctg aaggccacga taaatcgtgc gctgtcctct
    20341 ccgaacctcc ttgatcggct tagcaatgtc acccccctga aacacatcat ctaaaacaac
    20401 cattccacct atttttaagt gctttaacac ctctggaaga aactgaatgt attttgattt
    20461 tgcagagtcc ataaaaacaa agtcaaactc gccagtaagt cctgctaaaa gatcagccgc
    20521 atctccttca agaagggtaa tttgcttgcg gctatcgtat tttgcaaaat tttccttggc
    20581 aaagccaatc atctcagcat tgcgatcaat cgttataatc tctgcctcag gagcattttc
    20641 tgccattagc aaggcagaaa agccaatagc tgtgccaatt tctaaaatcc ttttgggctg
    20701 caagctttgc aataaaagcc tgaaataagc aacaacctca tgctggataa tgggaatatt
    20761 ttcttgtctg gcaaaggcct caagctctgc taaaaagcct tcgttttgct ttagctgcgt
    20821 tcgcatgtag tgaacaatgt cttctttgac aatagagcgg cgcatattat gatttgcatt
    20881 tttactatat gatttaacca tgctatccat tatataaaaa aactctaggt aatgctaggg
    20941 ctttcactag cctattcacc tttgacgatc tgagtagtat ctatcaaagg agctcacaga
    21001 cagccttaag ctgcttgaca atgctatcac aagcagacaa gtcctgtaag ggataatcag
    21061 gattggcaaa gccgatacag gtcatctgag cagccttagc agcctgacta ccatgcttac
    21121 tatcctcaat gacaaggcag gtcttgggat caacgcttaa ccattcagca gccttaagaa
    21181 aaatatctgg cgctggcttt gagcgagcaa cctcttcacc actaactaac acctcaaagc
    21241 agtccaaaag acctagtgca gtgagatttc taataatatc tgccttaggc gatgaggaag
    21301 ctactgccaa gcgatagccc ttcgcatgca ggtgcttgat taattgagca gcacctgcta
    21361 tggccttgac accgtcacgc tcaagcattg cttgacgacg atgattcatc tcagcgatga
    21421 gggcttcaac agaatcctct agctgacact cctttttcat agttgtccac atatcgtcaa
    21481 aggtggttcc cataaactgg tactgatacg cttcattggt atctatgcct cggtccaata
    21541 gcatttgtgt cttggttgac aaaaagatat attctgagtc aacaatcaca ccgtccatat
    21601 caaaaataag gcttgttttc atcatctacc tcctcttatg ctatatctca gtcaggtcaa
    21661 gagcaagact attaattact agagctattt ttaccagaaa aaagctcaac aatatctgac
    21721 agctgactaa tatgatgatt atcatcacta tctggcagca ataggttgat agagctaatc
    21781 ccagctgccc ttgctgcagc aaggtctaag ggcctatcac caatatagta ggtctgcgac
    21841 ttatccatct gataatgatg aatgagaaaa agaagcgctt cagggtccgg cttacgctta
    21901 aagccacaat ctgctgtaat cacctctgta aagtaatcag caatccccag acgctgcaaa
    21961 acagcctgag tggttcgtcc tttatgagtc acaataaaag gcttaacccc ctgctgagag
    22021 gttaaggcta atgtttcctt ggctgtaggc attagtgcta ttaggtgatc acgcgcttcc
    22081 tgctctcggg taaagaaggc cagcaattct gaaaaatcca gctgatgtgc ctctgctaac
    22141 ctcttcaaaa gctgtccgat ggattcttga ataatcgtat ccataaccca agcctcatca
    22201 aagggcagct gataggtctg atacaataaa cctagcgcct gacgaatagc ctcagaggat
    22261 tggactagag ttccatcaaa gtcccaaatg agattaactg tcacaatcct tacctcttaa
    22321 atcaatccaa taacgagcaa tagcctgccc tgctaagctt gtagtagggt aatcatctgc
    22381 cacctgaaca atatcctcta aaataccacc agccttttca atggtttttc gactggctat
    22441 attatcttta ttagctgtta ttaagacacg cttgatccca cgctcttgat attgctgtaa
    22501 tgcaaaggcc agcaagtctg tcataattcc acgcccgcga taatctgtcc ttgtcacata
    22561 gccaatatgt ccgccaattg ttgctaagtc tcctttttcc aactgccagc gacagcctat
    22621 tctagccact agctgaccat ctaaaaaata gtaataatta gtgctagtgg accagtcagg
    22681 atgatcagtt tggacctcaa accgtctaga ttgctcaaca aaggctgcaa agtcctctac
    22741 ttttttggtc tcaacaaagg tattacctga agctttttca gctaacagta tatcctgaaa
    22801 gcgcttaaag gctgcttgat cagctaaagc aattgttcta atctctttca tgcctggctc
    22861 ctttttatta tgctaaaaat caactgggca tttctcaagc attcatcatg ccaacgaaaa
    22921 agagctgccc ctagaactgt tgatgtaata ctacgtctag aggctgccca caggccttta
    22981 agctaggctg atagacactg actgctgcta tttaccaata gctcaaaacc taagaggaga
    23041 tggcaactat tagagatgtg cccctcttgc cactaagtcc tctagctctg tcaaacgctc
    23101 ttcaaagacc ctaaaggctg cttctaggta atcaccctta gccatatcaa caccagcctt
    23161 ggcaatcacc tcaagcggat aatctgaatt tccagacttc agataggtca agtagtgatc
    23221 aatatcctct tgagtaccat gcacgatctt atcagccaag tagctggctg cagcaaagcc
    23281 tgttgcatat tgatagacat agtagttgta atagaaatgc ggaatgcgag cccactcata
    23341 ctggataaaa tggttgtcct ctttttttaa gccataatat ttttcgttta aatcagcata
    23401 gagattattg aggtattcac ttgttaacac ctcgccattt tgatccgcct gatgaatagc
    23461 gtgctcaaac tcagcaaact gtgtttgacg aaaaaccgtt ccacgaaaac catctaggta
    23521 atgattcaaa atagcaaagc gctccttatc atcctgcacc tcatgtaaca aggcctcagt
    23581 catgatattt tcattagtgg ttgaagcaat ctcagctaag aaaatgctgt aatctccata
    23641 cacgtaaggc tgtgtttcac gcgtaaaggt tgagtgcagg ctatggcctg tctcatgcac
    23701 tagcgtatag aggttatcaa gcgtgtcctg ccaatttaag agcataaagg cattggtatc
    23761 ataggaacca ccagagtaag ctcctgagcg tttgccctta ttgacatgca catcaatcca
    23821 acgctctgta aaggcacgat gcacacgctc tgaataatcc tggccaaaaa cagccaaaac
    23881 cttctctgct ttttccaagg cctcatcata gccgatagca agatctgtct cagataaagg
    23941 agtataaaca tcatacatct ttagatcatc taaaccaagc acctcttgac gtagcttcaa
    24001 ataacgatga agcagcggca aatgcttatt aacgttttct agtagggtat cgtaaacagc
    24061 ctctgggata aagttggctg acatcgctgc ctgacgggct gaagcatatt tgtgaacacg
    24121 tgccttataa ttttgcacct ttacattggt ttgcagggtt ttagcatagg tgtgctggaa
    24181 ttgctcataa gtactataca tggcttcata ggcagcccta cgcaccttgc ggtctttcga
    24241 ttccatcaag ctaatgaaat taccatgtgt tagctcaacc tcttctccct tatcatttgt
    24301 cacaatagga aaagcaatgt cggcattatc taggatacta aaggtctcct cagcaccatt
    24361 aaagatttct tgtgcccctg ctaatagctc ctcctcagcc tgactaagga catgctcacg
    24421 cgtcttgaac aatttatcaa agaaatggtc atagactgtt agctccggtg tctcagctaa
    24481 gaaggcttgg taggcttcct gacttaaggc cataaattct ggctcataga atgaaaaggc
    24541 ttcactaaat ttagcataaa taccagaggc cttagcttga tattcttgat acttggcaac
    24601 tgtcgtatcc tgatcatttt tcatgctagc ataaacataa accttttcaa cacgacgagc
    24661 cagctccaaa tgcagctctg tgatatctaa gagactgctg cttgaatcca acaaatgccc
    24721 agcctgctgc cttgcagcct caattgctgc cagcagacta tctgcctctg tctcccaagc
    24781 tgcgtctgtt gcaaaaatag tgcttaaatc ccaagtgtac ttttcctcta gatgactacg
    24841 attatctgtc atacggacct cctaagtttc tattactaat cattttaaca taatatgctg
    24901 gtgaaaaaag cttttgcacc tctttatttg ctgcttttgc gtaatatttt tcaaagcaat
    24961 cgtaatagtg gctcaaatcc tcatgaatct ggcaaaagcc agctgagcaa gcaatcggct
    25021 taacctgtgg ataataagcc tctaggggcc tatcaagcag gttatcccca gctagataag
    25081 cctcttcttg ctttttcaac catttgctat cttttgctag taaggctttt tgaatccttc
    25141 tcagcaagtg cttatccatc tggagctgat aggctgacag gccttttctt tggtaaggca
    25201 gccgcaaaaa ggccaacaaa tcatcatcta aggaacaggt ctttactaga tagctgacct
    25261 taccaaataa atcctcatga atcata
//
LOCUS       DARYMD010000032        24197 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYMD010000032 DARYMD010000000
VERSION     DARYMD010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24197
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(93..869)
                     /locus_tag="TU818_001247"
                     /pseudo
     CDS             complement(93..869)
                     /locus_tag="TU818_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            complement(965..2512)
                     /locus_tag="TU818_001248"
     CDS             complement(965..2512)
                     /locus_tag="TU818_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL0924067.1"
                     /translation="MKTSLKKNNKFWTAALAVIVSISCILGLWTVVYAKEKSSDAPTK
                     NEAVQTEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGNDEIIRKVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISK
                     MEKEAKELQEKFDKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKK
                     EIDKLTDKVKELEKKATETKKSSEAINSVTPISPISGIKTSSSISPQTPQTSVSSSGK
                     GSSDTVSSGNATKDTSKTEVKEKEKEVRYSNKLTAKAPANNSSQDSSMEGASSNVNTN
                     KGVASSPSKARGTVTENKDNGNKDYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEIVKEEPVKEEVKPEKKEEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEETNDVDE
                     VEAEDEQ"
     gene            complement(2487..2726)
                     /locus_tag="TU818_001249"
     CDS             complement(2487..2726)
                     /locus_tag="TU818_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0924068.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIMI
                     CRKNNITISDLMTKVNREKAELKKERTNENQFEKE"
     gene            complement(2739..4862)
                     /locus_tag="TU818_001250"
     CDS             complement(2739..4862)
                     /locus_tag="TU818_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0924069.1"
                     /translation="MDGKLKKDFRERHKASLEREMLKAETSSIPEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKISKVRSENEQIEGTSKRNAKYRASDKGSVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     NKYKRKNYSESLYTRKKDDVPKENKPEDKKAGKDVAGEKEHSSLSKDQKKKLKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     ELTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFVGIIILGNFVINFAGTGMTGFMNSTNSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKSVSEVETILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRRVFKDYPDNLKHYEALFLAQGNMGEAFRNSDLI
                     SANGGVGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGYIRVT
                     TLDDWIATFCKHHPVGFGFPPNVNR"
     gene            complement(4866..7295)
                     /locus_tag="TU818_001251"
     CDS             complement(4866..7295)
                     /locus_tag="TU818_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL0924070.1"
                     /translation="MNKKRKIQQLKLEENKKALKKERKDLKQSKGKSNKEKSGLLDLI
                     FRKEQKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLDIDILSNLKSMGVRAESLTVEERLKILHD
                     ILNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFNGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYERYFENPTYDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            complement(7207..7596)
                     /locus_tag="TU818_001252"
     CDS             complement(7207..7596)
                     /locus_tag="TU818_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL0924071.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAFIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSATKVRRKQKGIKKGEKGLKAK"
     gene            complement(7600..7863)
                     /locus_tag="TU818_001253"
     CDS             complement(7600..7863)
                     /locus_tag="TU818_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0924072.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLHNKAAELEERTQDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEEFSKGKEDGR"
     gene            complement(7883..8749)
                     /locus_tag="TU818_001254"
                     /pseudo
     CDS             complement(7883..8749)
                     /locus_tag="TU818_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8769..8984)
                     /locus_tag="TU818_001255"
     CDS             complement(8769..8984)
                     /locus_tag="TU818_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL0924073.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            complement(8988..9299)
                     /locus_tag="TU818_001256"
     CDS             complement(8988..9299)
                     /locus_tag="TU818_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0924074.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGKEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKADKAKDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            complement(9463..11244)
                     /locus_tag="TU818_001257"
                     /pseudo
     CDS             complement(9463..11244)
                     /locus_tag="TU818_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565754.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            complement(11241..11726)
                     /locus_tag="TU818_001258"
     CDS             complement(11241..11726)
                     /locus_tag="TU818_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL0924075.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALAQSEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            complement(11723..12497)
                     /locus_tag="TU818_001259"
                     /pseudo
     CDS             complement(11723..12497)
                     /locus_tag="TU818_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(12494..13273)
                     /locus_tag="TU818_001260"
     CDS             complement(12494..13273)
                     /locus_tag="TU818_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL0924076.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDSKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKEDDLQKLKNFTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYNFSENGLGTFQNVFLAAEDISDLQIIMNSQLDNYIERLSAYIKSTG
                     KTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            complement(13360..13641)
                     /locus_tag="TU818_001261"
     CDS             complement(13360..13641)
                     /locus_tag="TU818_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924077.1"
                     /translation="MRWIIKIILFPFSLLLSVLTAFLTFILGIGTTILYFLMLMCIVA
                     AIGSFMQKDISLGIEALVLGFLLSPYGIPMVGAAVIAFFKGINEAIKSI"
     gene            complement(13661..15292)
                     /gene="rlmD"
                     /locus_tag="TU818_001262"
     CDS             complement(13661..15292)
                     /gene="rlmD"
                     /locus_tag="TU818_001262"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL0924078.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVETYLTTSPMRQKKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDIKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKYISVEIELDELDLTSAESKATYAKIKEYILEKFGFKVSTLYIAQIKRKCGIEL
                     RENYNKSKKDKQVIPQCTPEKEKAIMDALRHFKMI"
     gene            complement(15370..16800)
                     /locus_tag="TU818_001263"
     CDS             complement(15370..16800)
                     /locus_tag="TU818_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL0924079.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRILFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            complement(16999..17493)
                     /locus_tag="TU818_001264"
     CDS             complement(16999..17493)
                     /locus_tag="TU818_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL0924080.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     ALYDRLKKDRLCQRPLFLNHSEAELYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            complement(17486..18769)
                     /gene="aroA"
                     /locus_tag="TU818_001265"
     CDS             complement(17486..18769)
                     /gene="aroA"
                     /locus_tag="TU818_001265"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL0924081.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRI
                     SYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            complement(18902..19840)
                     /locus_tag="TU818_001266"
     CDS             complement(18902..19840)
                     /locus_tag="TU818_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL0924082.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFVGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMIFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK"
     gene            complement(19842..20702)
                     /locus_tag="TU818_001267"
     CDS             complement(19842..20702)
                     /locus_tag="TU818_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL0924083.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEINTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(20719..22002)
                     /locus_tag="TU818_001268"
     CDS             complement(20719..22002)
                     /locus_tag="TU818_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL0924084.1"
                     /translation="MSKHQDILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            complement(21995..22549)
                     /locus_tag="TU818_001269"
     CDS             complement(21995..22549)
                     /locus_tag="TU818_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0924085.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQPFYDMISHNSHYQFV
                     FPESMTKAESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            complement(22843..24132)
                     /locus_tag="TU818_001270"
     CDS             complement(22843..24132)
                     /locus_tag="TU818_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL0924086.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTTSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHKSDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKTFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
BASE COUNT         6490 a         5527 c         3925 g         8255 t
ORIGIN      
        1 gcattaaagc aaagctaaaa ggacttagcc ctgtgcaata cagaactaaa tcctttcaat
       61 aattattcgt ccaacttttt gggggcagta catttagtaa tcttttcttt ttgaatgaca
      121 tcagttattt caatcttatt gcccactaaa gttaagagct gctctgctgc tatttcatca
      181 tcaattctat ctgttgaaag tgtaaagcta tttgtagaaa gctctaccgt ataatatttt
      241 tctttcttaa agtttgctat ctcatcatct ctttttacga tcatagcaag agtcggtgtt
      301 tgtactctgc caacactgta attttgctta tacagacaag aatagagcct gctgatattc
      361 attccgacaa gccagtcagc gatagctctt gcctgtgccg actcaaagag attatcgtaa
      421 tcttttccgt cttttagatg atcaaagcca tctttaatgg cagtatcttc catagatgaa
      481 atccaaaggt gtttcatctt ctttttacaa ttcacttgat tatatacaag tctaaaaatg
      541 ctctcccctt ctctacctgc atcgcacgca ttgataaccg tatcaatttc tttgtcgttc
      601 atcaactttt taaggatgtt aaattgtttc ttggttgact ttgccacttc atacttatag
      661 tccttgggga taatcggtaa atcaaccata ttccacttgg catacttttc atcataaaca
      721 tccggatttg ccatttgaat taagtgtcca acacaccaag atactttgta tccatttccc
      781 tcataatatc cgtctttctt tttatttgct ccaagtactt ttgcaatact taatgctaca
      841 cttggttttt ctgcaatgac taacttcatt tctgtactgc ctcctgtttt caatataaaa
      901 gggcgaaaga ttttattctc ccgccctgca tttgcaccaa atactgtatt tttttggtgc
      961 agcattactg ctcatcttcc gcttctactt catctacatc atttgtttct tcctcgcttt
     1021 cagcttcaga aaagaaatca tcatcttctt cctctaatgc ttcaagctcc ttatcttctt
     1081 tcttttttac aaccttaaag tagtatcctg ctcccaatgc tccgcctaca acaagaagca
     1141 gaataatata tgttcctaaa ttactctttt cttctttttt ctcaggcttt acttcttcct
     1201 taacaggttc ttcttttaca atctcctgct ttggagcttc ttttttctct accatgttaa
     1261 gcaaatcatc ttcggatact tctgtaagaa gcatgacatt ctcactatcc tcatcgtggt
     1321 tgatgatgag atgaaaggtc ttaccgtttt tagtttgaaa ggtaataaac tgtcttgcat
     1381 cagcggaata ttgatccgtt tctttattat cgctgctatc cccatgatga atcggataat
     1441 ctttatttcc attatcttta ttttctgtaa cagttcctct tgcctttgac ggagatgaag
     1501 ctactccctt attggtattt acattactac ttgccccctc cattgacgaa tcttgactgc
     1561 tgttattagc aggtgctttt gctgtcaatt tattagaata gcgaacttcc ttttctttct
     1621 cctttacttc tgttttgctt gtatcctttg tagcattccc tgaactcacc gtatcagatg
     1681 agcctttacc ggaactactt acagaagtct gtggtgtttg gggagaaatg cttgagcttg
     1741 tcttaattcc ggaaatagga ctaatcggtg taacagaatt tattgcttca gaagatttct
     1801 ttgtttcagt tgcctttttc tcaagctctt tcaccttatc agtcagctta tctatttcct
     1861 ttttcatatc ttctgataag tccttatttc ctttatcttt cttcattttc tctttcaggc
     1921 tgtcaatttc atcttcaagg tctttgattt tttctttctg cttatccttg tctttaagct
     1981 caccatttaa cttatcaaat ttttcttgaa gctctttagc ctctttttcc atcttagaaa
     2041 tatcgtcttt agaaagctct gtctgtgtgc ctttatcctc cgtttttgta gcttctgttt
     2101 gcgtgctttc gtcctgcttt ggtttttctt cttccgtttg cgtttcctta tccttaacct
     2161 cagtctttgc taccttacgg ataatttcat catttccatc tccctttact tcataaaaca
     2221 ggaattcatc aataaatttc atatcatcag ggagcattgg aagatcgcca ctatcaagaa
     2281 gctgtccttt ctctgcctta atcttttctt ccttaaatac cttttcatct tcaaagatat
     2341 actttacatt tacttcaact tccgtttgga cagcttcgtt ttttgtagga gcgtcagagc
     2401 ttttctcctt ggcgtaaaca accgtccaaa gtcctaaaat gcagctaata cttacaatta
     2461 ctgcaagtgc tgctgtccaa aacttattat tctttttcaa actggttttc atttgtcctc
     2521 tcctttttca gttctgcttt ttctctgttt acctttgtca ttaaatcaga aattgtgatg
     2581 ttgttctttc tgcaaatcat gatgatttct tcattttcaa gttcttcttc acgaataaat
     2641 aaaggctcca attcttcatc aatcagagcc tttttatcct ttaacttttt tattctgttt
     2701 tttactgctg tcagttcttt tttcatattg ttccctcctt atctgtttac atttggtgga
     2761 aaaccaaagc ctaccggatg gtgtttacaa aaagtcgcaa tccaatcatc taaagtagtt
     2821 actcttatat aaccgatatt atcaataacc ttgccgtctc cgatatagat tccgacatga
     2881 ccataggtaa gtcctgctgt gcttccgcta ctgctgcttt ctaccgctac aagcattcct
     2941 accttgagct ttgacctatc ggatgtaaag gtatagtttc gatacatatc attagcattt
     3001 cctccgatat atccaagtcc cgcattttgg taaacttgcg atacccacat ggcacaccag
     3061 cctgcacccg gagatggagt gatatatgca gcattaacaa tcttcttttg tacttccgaa
     3121 gatgcctcat actctttccc accacctaca ccgccattag cactgataag gtcagaattt
     3181 ctaaaggctt ctcccatatt tccttgagca aggaataagg cttcatagtg ctttaaatta
     3241 tcgggatagt ctttaaagac ccttcggata atgctgtcca tctctttttt atgaagcgtt
     3301 acaatgagct tcttatattc ataaggctct tcatggcttt cggtatattc attgccatct
     3361 tcatcggtat aggtttctgt aactgtcctg tatctgattt caatttcttc cctgtattca
     3421 aggtcataca tggactcaaa caattctttt aatatggttt ctacttccga tacactcttt
     3481 acctctccgc accttgatgt aatgtaggat aaaagctcat ggacattatg accgatatac
     3541 tctgtgttgt ttaagatata ctcatcatat ccgggataat tctcttctac atgatccact
     3601 tcactttgaa gctcactctc catagcagaa aacttctgat tgatttcact tagaacattt
     3661 ggctttgata aatagcttgt tgtaagaaca gagtttgtag agttcataaa gcctgtcatg
     3721 cctgttcctg caaagttaat cacaaaattt cctaagatga tgatacctac gaagataagc
     3781 attagtcctt tggcttttcg gataatcata tcctttgagc ttttcagtgt tccgataagt
     3841 ccctctttaa tccgatctct gagtcttgac ttattctcac gagaaatcgc tgcctttacc
     3901 tgatttttct tttgaaatct tttataggca cttgctcttt tatactcatc tgtctttttc
     3961 agttcctctt tggcatcacg aaactctaac ttggatttac gctttctgat tttatagtcc
     4021 ttatttgtaa gctcatatcc ttttttagct cttttcttat ctgagtatct ctttatacca
     4081 tgaatgagtt ttgaacttgc atcggctgtt ttttctcccg cttctacgcc tttattttca
     4141 tcacttccat gagaaaggta atctcttacg gtttcacttc ctttggcaag tcctgacagg
     4201 gcagatactt ttaccatatc tttcttcagc tttttctttt ggtcttttga aagactgcta
     4261 tgttcttttt cgcccgcaac atctttccct gcctttttat cttcaggctt attctctttt
     4321 ggtacatcgt ccttttttct tgtatagagg ctttcggaat agtttttcct tttatactta
     4381 ttcttttgag ccttatgatt tttagaggga ttttctaatg atttttcttt ttgaggtaga
     4441 ttatcctcta catcataggt tgattcaaag tagtcgctgt ccctaaaatc attatcgtat
     4501 ctgtctatga ttccatcatt atcaaggtct tgtcctaaag aatcatagat tttcccgttc
     4561 tttacctcag tatcatagtc agcctttcct gcttcattta cacttccctt atcagaagcc
     4621 ctatactttg catttctttt agaagtcccc tctatctgct cattttcaga tcttaccttg
     4681 cttatcttct catgaacctt gtcctgaaat ctatctttgt catggacaat ttttcctctg
     4741 taatcatcgt tatgctttag cttactttct tcaggtatag agcttgtttc agctttaagc
     4801 atctcccttt caaggcttgc cttatgcctt tctctaaaat cttttttcag cttcccatcc
     4861 ataagctacc tcacttcttc aggcttggta gtcatcttct gataaagaat tgtatctttc
     4921 ggaaacttat caaggaaagg cacaatggta tttccaaaga aaagtagtcc ctcgccctca
     4981 ttggagttcg taacatatct aagctgcgga agtgagattt taagtttcct tgcaagtatt
     5041 tccctatctc ccgaagcctg atttaacatt aagacaaagt ccgtattatc aaagatattt
     5101 tcaatttcct tactcataag taggtctttg acattttgcg tgataccagt cgggattcct
     5161 ccccattttc taaaacgctt ccaaatctct accgaatatg aagctgtctg ctcatctttt
     5221 aacagcaagt gaaactcatc tatatagtac cttgtagcct tgtttcctct gttttgcgat
     5281 accttattcc acacctgatc ctgtataaca agcataccta ttttctttaa ttgacttcca
     5341 agctccttaa tatcaaaaca aagtagcttc ttatttaagt ccacatttga cctgtgatta
     5401 aagacattaa gagaacctga aacataaatt tccatctctg ttgccagctt tttccctacc
     5461 ttttcttcct gcccttttaa catatcgtat aggtcttgaa gtataggcat attgtcataa
     5521 gtcggatttt caaagtacct ttcgtaaatc ttaggtaagc atctatctat aacggacttt
     5581 tcttccgctg taagtccact accaccaact acaagctcaa gcatagacat aatgaagttt
     5641 gccttgtctt taagaggtgc gtccccatca ccgtagttca tatttatatc aagtggattc
     5701 aggtaatctt ttgacttact gctgacctta atgacttctc cattaaactg tcttacaagg
     5761 tttccatact ctccctccgg atcacagata atcacatcat cgtccgttac taaaatcgca
     5821 tttgccatct ctcttttggc actaaaggac ttaccactac ccggagttcc taagattaga
     5881 ccgtttgggt tctttaattt ctttcgatcc gccataatca ggttatggct taaagcgttt
     5941 agtccatagt ataggctatt acttgaattg ataaaaagct cctctgttgt aaaaggcata
     6001 aagactgctg ttgatgatga ggttagccct ctatctattt caatcttgtt taccccaaga
     6061 ggcagcacgc tcactaagcc ttgttcctgc gtatggtcaa gtcttttcaa tttacagtta
     6121 tgcttgtttg caatggagct tatctgagct atggtgttat cgagcttttg cactgtcctt
     6181 gcaaaattca taaagacaat acttacaaca aacatacgct catctcttgt ctgtaaatct
     6241 tttaaaagac tttttacatc ttctccgtaa gtaattaaat cacttggaag aatgtccatg
     6301 tcatagcctg accttacagc tttcttgttt tcctcaattc gcatcttatc aatatcggtg
     6361 ttttttcgtt ttaccatctt gatggcttct gactggtcaa tcgccttaat atgaaaagat
     6421 atattgatgt tatcatcaat atccaaaaac tccgataaca tacggtctga aagctcactt
     6481 gcaaggattt gaaaatgact tgttgctccg ataaacttcc caaacttgaa atacctgctt
     6541 ggcataaagt taaattcatc aggcacgata tatgttttgg tactttcctt tttcttcagg
     6601 tctttgtagg aaaactcaaa ggtcttattc ggatttaata tatcgtgaag aatctttagc
     6661 ctttcctcta ctgtaagact ttcagctctt acccccatgc ttttgagatt agataatata
     6721 tctatatcca atctttcaag ttttgatgta gcctgttcta aattgtctgc ctctactgta
     6781 aaggttacat actttgattt tttcagtccg ttatttcctt ttacaatctg actttttagc
     6841 atctctctaa actcaagtcg tatatcgtca aatccgtccc ctttatccgg tatctgaatt
     6901 gccgatttca tttcttcgtt tcgtccaagc tgattgatgt aggaaaactc aatcgctatg
     6961 cttggatcaa aggaatttag aaagtttgca aactgattaa aaatcaaatc cctatcttca
     7021 tctaaagcaa gctgatagtt aatgtcctga aaggctatgc ttttactgaa gtgcttttca
     7081 tcgagctggc atatcccgct ttttaagagt ctaagatagg gaatggtatc ttctaccgta
     7141 tagcgttttt gctcttttct aaagataaga tcaagtagtc cgctcttttc tttgttagac
     7201 tttcccttac tttgctttaa gtcctttctc tcctttttta atgccttttt gttttcttct
     7261 aactttagtt gctgaatttt tcttttcttg ttcaaggtaa acctcctttc tcactctctt
     7321 tgccggctga taaaacttat gaaggtagat atgcttaaaa tatttctcaa aggtcagtcc
     7381 gtccttttca aaaagtgtga taaaaaagat tggaagtgtg gacacgataa ggaatatgaa
     7441 agctatatcg tttggtacta cctttctcat aaataaatag acaggtattc caacaagtcc
     7501 tgcaatggta aatcctatga gctgtctttt tgtaaggtta aaggctacct ttgtcttgac
     7561 cttctttaag tccttgggta ttggtacata cgccatagct tacctcccat cttctttacc
     7621 ctttgaaaac tcctcaaagt gttcatatac agagccgatt tcatcctgaa taattgcaag
     7681 ctgttcatct gtattcttgt tatatctttg ctgcattaag caaaaatcat tatggcagcg
     7741 accgatgtcc tgtgttcttt cttctaattc ggcagctttg ttatgaagcc tgattctatc
     7801 aattaccgcc ataatgcctg cgaccattac tactgctgta aatactgttt ttcttttatt
     7861 catactatct ttcctttctt ttttagtgtg catttaatac gcttttggcc agtgttccgc
     7921 tctttagcat cattaacccc agcaaaaccg cataaccaag tatcgtcatg gtacttgtgt
     7981 gtatatctgt tatttcaatc gtcttaacta atactgcgta aattccaaga caaaccatta
     8041 aaaagagtcc ttgtagtcca agtgcaaata atcctttgat gtaatttgtg ccaatttgcc
     8101 cccattcttt gtttcccatc gtggcaaatg gaatggctga aaccgatgaa taaacataaa
     8161 tctcaaacat ccttccgtaa accacaagca taatcactat ggaaattgcc tgtatggcaa
     8221 ctttaatgag cgaggtttca aagagaatca tgataagctc tccaagtccc ttttctttta
     8281 gggtatccat catcgccact atctgatctc cggaaacggt ggcagaggtg tttatcaccc
     8341 ctgccgcctt atttaccata tgctgtgcta catcaaagac cgccattgaa aattcaaaag
     8401 cgtgagatac caaccataca gcaattcaca tcttgatgat gtacttgaaa aattcaaatg
     8461 tatccgtatt atcatgtagg ttatttttct gtataaccat attgataagc tcgatacaaa
     8521 ggactgctgt gataattagt cccgctatgg gaataatgac cgaatcgtta atgcttttaa
     8581 taaaggtaaa tacatctcca ttccacccca taggagtttt tcctacatct gttgcaactg
     8641 caccaacctt gtcgttgatg tcaagaaaca tggactctaa gtttgcttgg ataccgccca
     8701 gtagaagctc cttaaagaat tcttctattt tgtcgaatat cccaaacatc taagctctcc
     8761 ttttcttctt atctgagtac atttgcaaga agtggaatca gcttaagtcc gataaggaca
     8821 atacctcctc ccgccatcaa ttgcttgatc ccttgacttt tggctcccgg attatcgtta
     8881 ccataacctt ccatcaggtt aatgacaccc catgctccaa gtcctgctcc tactgccata
     8941 accaaaatct ttaatacatt tactgcctgt gcgaaaaatt ccataattta ttcctcctca
     9001 ttttcttctt tcttttcaat cttgttgtat gacttcacta caaaattttt gtaagtcttt
     9061 ccctcttttt cacgcttctt aaagtagccg aatacatgaa tcaaatcgcc cttttcaaag
     9121 tcctttgctt tatccgcttt ttctccatag gctgcacaat tgatgtactc cttgccttta
     9181 ccgtacttct ttacaagcgt aaaatttaca acttctactt ctttaccctc tttttcaaaa
     9241 cttgagaaag taggttctgc cactaagttg gcgttgatgt taatcatttc ttgcttcatt
     9301 aaaaatttct ccttttcatt tcaataaaaa aagcgaccgg aagtattact tttccaatcg
     9361 ctatactcat actatttagt tttttactca gtgggacttc tgatccttat catcttgcct
     9421 ccttactttt gcataaaaaa gcagcaaatc tattttgtag acttactgca ttcttgtaat
     9481 aactgtttcc ctattcagtt ttgcttttcc tttccgtttc atgtagcttt ctatatcaaa
     9541 taaatttttc ttatcatagt cctcaagcag cttatagttc ttgtgctttg taatatcgta
     9601 cttatctgaa agaaaaggtc tgacacctct aagctgaaag atacattttc caccatccat
     9661 gaccgtaatc tcatcctgac tcatcagctc tttgcctgtt ttttgatagt taagtccaaa
     9721 gctcttttga tttgaccttg tttccgatgt gttgtaaagg tcgatagttt ctttaccaag
     9781 cgtttcggac agctctttta gtgttttttt cctttccacc taagaataag gtactatcac
     9841 agttacccac aatggtatca gcattatcct tatatattgc ctttagctga gattgtgcct
     9901 gtaagataat actcgctgaa atttctctac ttctaattgt ggctatgagc ttctcaaact
     9961 ttggaattaa gccgatattt gcaaactcat caagtaagca tcttacatga acaggaagtc
    10021 tgccaccata tacatcatcc gccttatcgc aaagtagatt aaataactgt gaatacataa
    10081 tagacactac aaagttaaag gtatcatctg tatcagagat aataacaaag agtgctgtct
    10141 ttctatctcc caatgtatca agctcaagtt cgtcttcact catcaaatct ctaagttcct
    10201 gaatatcaaa tggagcaagc cttgcaccac aagatataag aatagatttt gctgtctttc
    10261 ccgcagccaa tttatatttt ttatattgct tgaccgcaaa gtgcgtaggc tcctttttct
    10321 caagtgcttc aaagagtctg tctattggat tcatataggt ttcatcatct tctcttactt
    10381 ctgaagcgtc tatcatatca aggagcgttg caaagttctt ttcttctctt ggagcttcat
    10441 agaagatata tccgataagt gctgtgtagt agagtttttc cgctttgacc caaaaatctt
    10501 cacccgcttt ttctccctca ccttttgtat ttgcaatgat tgtctgcact aatttgagta
    10561 tatctttctc agaatggata taggcaaagg gattgtattt catgctcttt ttgaagttta
    10621 tggtatttag aatttttatc tcatatccat tgtcttcaag catcttgcca cattcaatga
    10681 ctatcgttcc tttcggatcg gttacgcaat agctactgtg catctgcata aggttcggtt
    10741 ttacataaaa tcttgtctta ccacttcctg atccaccgat tacaagtaca ttcttgttac
    10801 gagcatactt tggattagcc ggtctaccat tcatagttag gcgttctgtc tgggtaagca
    10861 agatattgtt ttgaaacttt tcatccatgt atggctcaat atctttctta tttccccatc
    10921 ttgctgagcc atactctttc ccctgtctaa actttttagc attttacctt tggtatagac
    10981 aataaattta attaaagcag ccattcctat gcccattaaa atatccgccg gatgaatact
    11041 tggaagaaaa ctcatcgtgt tgatctccaa tatcccttga aagattttat ctatgacatc
    11101 accaccggta tagcttctca catgatgggc aaagatgttt cctaaataga aaaatgcaag
    11161 atagggaatg ttttgcttta caaactttgt cttatcctgc accttaaata agcctttgat
    11221 gtcctttaat attttatcta tcataggctc tgctcctttt gtttattctt gattttatct
    11281 ttggaaacag agttcttagc catttcctta aacttctcaa tattcttgtg aatagattct
    11341 ttcctttccg ttttcttttc agactgtgct aatgcgtgct taaaggcttt atccatcact
    11401 ttcatatctt tggcttgaaa gaatacagag tattttcctg tttccttatc cttcatcact
    11461 gaaaacttaa caccataccg attaagttct tttttcagtt ccttaagctc cgcttcttca
    11521 acaggaattt cttcaagctg tccctttttt accatatctt ttagctttac ttcatttccg
    11581 ttagcattaa ccagcttttc aagtcctcca agtttttctg cttctttcat caatttcttt
    11641 aataagttca gaattaactt tcctgttact ttagcagctc ttacttccat attcagcgtt
    11701 tttcttgcta tttcttcatt gatcaagttc tctcacctcc attcagtaac ctatctttat
    11761 ttcgattcaa tttatctctt tgaataatct ttctaaaatc ctctttggat tgtgtcgtag
    11821 gaaaggttag tggtgaagat agtcggtttc tgctttaagt acctgttgtt gacaatgtta
    11881 tatacctgct ctttggcata gcttgtatct ctttctattc ccaagtcatc caagataaga
    11941 acggaagtat ttacaaggga ttcaatatat gcgttcttat caaaatcaaa tcctcccttt
    12001 tgcagctcat tgataagctg tgcaaaattt cttattttaa cgcctatttg atactgttca
    12061 ataaggctat ttgcaatgga gcaggcaaga taggtttttc cacttcctac tgagccgtaa
    12121 aatagcagtc cgatattttc ttttttcatc tgctcatagt cttttacaaa attctttgca
    12181 atgataagac tttgattttc ttctccctga taattttcaa aggtgtatga ccactgaata
    12241 atagagttaa agcagttctt ttttaatcgt tctatttcca tctgcttttc tctttctttt
    12301 tttcttgcct ctctatctct atcgcatttg caagaaatct taaatatcat cttgttatca
    12361 aagaactcca tcacttttct gtcttttctt tcatgacaaa ctttacaaaa ggcgtgtccg
    12421 tccttgatat attctttttc aggatcgtaa gaatactcta catcctctat cattactttt
    12481 tctaattctt ttatcatagg tgttctcctt tatcatattc ttcccatgtc gggatatttg
    12541 atgttttcac ttctttgccc cttccctgat ctttataaaa ccatgaaagg attgttgcct
    12601 tatggtcttt ataggtcttt ccggtgcttt taatatatgc agataatctc tcaatataat
    12661 tatcaagctg tgagttcatt atgatttgta agtctgatat atcttcagca gctaaaaaca
    12721 cattttgaaa tgttccaagc ccgttttcac taaaattata ttctctctta ctatacttac
    12781 tcttattatt ctctatatag ttagagtcaa ggttcttaac ctcttgaagt tcattttctt
    12841 tacttctgag gttaaaatct tttacttctg aagtaaaatt ttttaacttc tgtaagtcat
    12901 cttcttttac ctgaaatatg ctcataaaat ctttgacata aatgatattc ggctttccaa
    12961 gtccaagccg tacccgttca atcagtccaa ttcctttttt actatctaat tcatctaatg
    13021 tttttatggc agtcggcttt gagatatttc ttcttttcat aatttcttcg actgtgaaat
    13081 agataaatac cctgccttcc ttatcaatcc agttattctt aaaggacatt cctgtccgtt
    13141 taagaagcat tgaataaagg ataattgctt cagcggataa tcctttaaat tcttctccat
    13201 caaccaatat ctccggtact tttaagaaat taaatctttc cgcttctctg ttataaaaat
    13261 agtcaaagtc catcgcttca cctccctcct taaaaatttg caaagaaaaa gacgatagtt
    13321 tttctctatc gcctttggta accattttta tgaaattttt tagattgatt ttattgcttc
    13381 attgattcct ttaaagaatg ctataactgc tgctccaacc atcggtattc cataaggact
    13441 taacaaaaat cctaatacta atgcctcaat gccaagtgat atatcttttt gcataaatga
    13501 tcctattgca gcaactatac acatcagcat taagaaatac agaatagttg ttcctatgcc
    13561 aagtataaat gtcagaaagg cagtaaggac actaagtagc aagctgaatg gaaacaatat
    13621 tatttttatt atccacctca tataatacct ctcctttctc ttaaatcatt ttaaagtgcc
    13681 ttaacgcatc cataatagct ttttctttct caggtgtaca ctgcggaata acttgcttat
    13741 ctttttttga tttattgtaa ttctctctaa gttctattcc acattttctt tttatctgtg
    13801 ctatatatag tgttgaaact ttaaaaccaa atttttctaa tatatactct ttaattttag
    13861 cataggtagc cttgctttct gcacttgtca aatcaagttc atcaagctct atttcaacac
    13921 ttatatactt atcgacatta agtttggaca ataatgctac cgtctcgaca tgatgtgtca
    13981 ttggaaacaa gtctactggc tggactttct ggagtttata gccgagttcc tcgtagcgct
    14041 tgatgtcacg cgccatggtg gcggggttgc aggatatata ggttattttg tcaggctgca
    14101 tcgctgcact ggccttgata aagctctcag ttagtccctt tcgtgggggg tctacaatga
    14161 taactgttgg ctttatgccc tcctgacacc agtttgccat cgcattttca gcgctgtcag
    14221 cgacatagta ggcattggta ataccgttta gcgctgcatt tttctcggca tcacgcactg
    14281 ctgcttcgat cacttcgaca ccgtatactg ctttgacttc tttagcaaag gatagcccga
    14341 tggttccaat gcctgaatag gcatcaatca ccacatcgtc agcggtcaat tcagaaaaat
    14401 caatagctgt ttgatagagc ttttcagcca ttgttgtatt gacctgatag aaggactgag
    14461 cagaaataca gtattgattg cccaagatcg tatctgtgat tgtctctttt ccataaagcc
    14521 ttgtaaacgc cttaccaaag ataacattag taggcttgtc attgatattt tgcaggatag
    14581 aagtaatcgc tggaaattct gcgacaaggc tatcaatcat ctggttgata cgaaagattt
    14641 taggtcgtgt tgtcactaaa accagcatga tttctcctga ataatgccca cgacgaacca
    14701 caagatgacg aatcaggcct gactgctcct tttcgtcata gggcttgatg tcaaaacggc
    14761 gcaaaaggtc gcgtgtaaag gcaatcaagc gatcaatttc cttatcttga atgtaaaaat
    14821 cagaaatcgg cactagctca tgagaatgct tacggaaaaa accagtctct agctgaccat
    14881 tgacacgacg aacaggaacc tgggctttat ttcgataagc ataaggatat tccataccaa
    14941 ttgtttcttt gacctcaaca ttgctaatcc ctgcaatctt atagagacta tcctgaacct
    15001 gcttttgctt aaagagcagc tgctgcggat aaagcaagtg ccccaaatca gcaatacctg
    15061 tacgcagata ggtcacatcc agcttttttt gacgcatcgg tgaggttgtt agataggtct
    15121 ctaccttgcc aaagccactg tttttattga cctttaggac acgcatctga atgatctcac
    15181 ctggaagagc attttcaaca aagaaaacaa agccttcatg cttagcgatt cctaagccat
    15241 catggcttaa atcagaaatt tccacctgaa caatatcgtt tttacttaac atttactttc
    15301 cttttctttt actacactaa tcactcaaaa aagaagagca accatcgtta cccttcatta
    15361 tagcatatct tagcgtaatc ccagcttaga taatcgattt tgatacttag caaaatcaat
    15421 aaagagagcc tgaccaccat acatgtcata ttcatcaatc caatccccat tttcaggaat
    15481 cgtcacatgc tccacaccgt ttttgccatt agtcaagacg gacactccat ttttaaggac
    15541 aaatgggaag gagacattgg ttgaggttag ggcataaatc ttaccaatag ctgctgagcc
    15601 cgtaaagagc ttggttggat ccttgatttg agacatgata gcagccatca cctgctgctg
    15661 acgtacggtc cgaccaaaat caccctcatc gtcctttcgg aagcgagcat agttgagcag
    15721 ggtacgacca tccatttttt gctcaccaac cgttatggtt tggttgggaa ccactccgtc
    15781 tttcattcgt aaatcatctg gtacatcaac agcagcgact gcttcgccat ttacagtagc
    15841 aaatttggca tcaatggtaa caccatctgg aaacagtgtg tcaatagcct cagcaaaggt
    15901 ttcaaagtca accatgacat aatatttaat gtcaatatca aaattatgct tgagtgtctg
    15961 acgcacaaat tctgctcctt gatgattttc ctgctctcct aaattaaagg aggcgttcaa
    16021 ttttaaatca taggaatcct gattattata gctatagcca ggaatattaa ccaaggtatc
    16081 cctcatgaag gagaccattt tgattttatt ctccttattg ccaacattaa ccaccatgat
    16141 tgtatctgtt cgagcatctg ttgagccttg cgtaatcctc tggtctgagc ctagaattaa
    16201 aatattagtg ccatcgctag tatcctgacc atgaaagacc tgcgaaactg ctggcttata
    16261 attggccttg ttagtagaca cgtccatcat tcccttgaaa aacatgaaag ctatccctgc
    16321 aacaagcagc agcaacaaga aaaagagtat tctgaaaaaa cgtctcagac gtcccttctt
    16381 ttttttcctt ctaccctttt taggcatagc ctcaggcgca agctcctcat agatcgcctg
    16441 atctgggtca tcatagaagt cctgctgagg ggctagtatt ggcttttgct gatgcctttt
    16501 gctacgtctt tctgatcttg gataaagagg caggccatta ggcccagcct gctgctcatc
    16561 actcatatca taagcatcag cattatcctg tgaagcttga gcataatcgt cacgcccacc
    16621 cctagtataa tgagtcaagg agcgctgaga acgagaaggc atagcccttg actccatctt
    16681 tgactttaaa aaggtaaatt ctctgcgttc agtctcagtc aaataattta aatttcttaa
    16741 taaataaaaa tatcgtaatt cttcgtggtg gcttagacca cccttttggt atctcgtcat
    16801 gctcttccaa ctcttagtat tctaatacaa tttcttctat tctttgtcta atgattctat
    16861 tataacctat attaacgaga ttgtcctcta aaatcgttag aattcaactt tatttcaacc
    16921 tatatattag cttttcatac ctaatcatta agaaaagctg ggctgcgaat aggaggccaa
    16981 aagtctaatc ctcagcagtt acgacatatt ggcaatgatt gctgcaacct cctttggtgt
    17041 tctatgctca acattaatca ctttgtctgc caatccctca tacaaggcca tgcgctgctg
    17101 aaaaatagca tagagttctg cttcagaatg atttaaaaac agtggtcttt ggcatagcct
    17161 atctttttta agccgatcat acaaagcctc aaaggaggct gttaagagga tattattttt
    17221 gtgatttttt ctgattaatt ctcggtttgc cttactaagg acaacacctc caccagttga
    17281 tacgatagtc tcattatcaa gtgccagcac ttcctgtaag gtatctgact caagctttct
    17341 aaaggctgct tcaccacgat aggaaaaaaa tgctgatatg ctcatgccta ttttagcctc
    17401 aataagccta tccatatcca aaaaatgctc atctaattgg gctgcaactg tcgtcttgcc
    17461 aactcccata aatcctaata gcagcttagt catgccataa cctctctaaa tccttaaaaa
    17521 agtcaggata agaagtcagg atagcttctg ctcgctctag ggtgacctgt ccttcttcaa
    17581 ccagtagggc tgcaatagct gtcatcatgc caattctatg atctccacag gtactgacag
    17641 ctgcaccatg taatggtgtt ttgcctctag tcaccatacc gtcctctgtc gcctgaatat
    17701 cagcacccat ctgtcctaat acatcagtaa cagcctgaat gcggtcagtt tccttgaccc
    17761 gtaattcttg agcgtccctg atataagtcg ttccctgtgc ctgagttgcc agcaaagcaa
    17821 taacaggcaa ttcgtcaatc aagcgaggaa tcaagtcacc agaaatctca atgcccttta
    17881 gggtggaata agacactttt agggtagcag cctgcctgtc cttatcaaca gcctgatagg
    17941 agatacgacc acccattttt tcaatgacct ctaaaagacc tgtccgcgta ggattaatcc
    18001 ctacattttc gagcacaaga tctgaccccg gaacaatcag accagcagct aaccaaaagg
    18061 ctgcgctaga gagatcgcca ggaatctgta aggtctgtcc ctgcaaacgc tgcggtcctt
    18121 tgatactgat ttgctttcca gctactgaga gctttcctcc aaattgttca atcatctctt
    18181 cggtatgatt tcttgtcaat tccttttcaa ggataacagt ctctccctgt gtctgcaaag
    18241 cagctaataa aatagcagac ttgacctgag cagacgctac aggcagctga taatggatcg
    18301 gccgcaactc ctgacagccc tttacaatta gtggtggaag ctctttttct ccttgaccag
    18361 atagctctgc tcccattaga gacaatggta tggtaatacg atccatagga cgccttgata
    18421 ggctatcatc tccaagcagc tgcaccgaaa aatcctgtgc tgctaatagc cctgcaagca
    18481 ggcgcataga agtacctgaa ttgcccatgt ctagaggctt ttgagctggc tttaggcctt
    18541 taaaacctct tccttcaatg attaaactat cagctgactc gtaaatggtg acacctaggt
    18601 ctcgaaaggc ttgaatggtg gctaaaacat cttgccccct taaaagacca tgaatcaccg
    18661 tttgcccctc tgctatagca ccaaaaatga ctgcacgatg gctaattgac ttgtcacctg
    18721 gtacccttag acgtccccta agcgccttag cttttgtttt taatttcatc attactccta
    18781 tttttagtac accagcatta gctcagcaaa gcaaataaaa gaaaatgaag taaggacaag
    18841 ggcccttacc ccatcaacta atcaccaagc accgtcttgt ttttcattct aagacaagcc
    18901 gctatttctt gggcggcgca ccatcattgc ctaatgtctt tttgatgaga gaaacaacat
    18961 tgccgctgcg cccctctaat ttgccgatgg atagctcttg ataggtagcg ttaaaaaccg
    19021 cccccataat caatatcctt gccaggaaaa taaaccatag catgatgata aaaatcatca
    19081 ccgaaccaaa ggttttaata tcgaccattc gctccacatt atgcaccaca taattaccaa
    19141 ccatattgct caaaaaaatc atgacaaagg tggtaaaaaa tgttcctggt aagatatacc
    19201 tgattttctt gattttgata tttggcaaca aaaaataaag caacatcaga ccaacaaata
    19261 taatcagtat cgtaatcggc tgaatcagga acaaaaagag cgtcgtgatg ttatcattta
    19321 agtgataatg cctatccagc acctgaatcg ctgccttaga aaaggttgaa aaaatcaagg
    19381 caaaggtcaa caaaaacagg atcagcaggc tcgtcagcaa gcctaccaaa tgaccgagca
    19441 aaaagtcacg atgctcagaa gcatcataag ccttattaaa ggccttttgc agagaggtta
    19501 ggcttcgcga cattgtccaa agccccgtca aggtcgctac tcccagcaca ctgcctgatg
    19561 gcttagaaaa aatattaacc acaatggagg aggcagagcg ataaatatcc ttaggcagct
    19621 gctccttcat taagcgtaat aaatctgaaa tatcaatatt taaataagga aaaatattag
    19681 ccgcaatgac aatgagtgga aaggctgtca aaataaggta ataagcaact gcaatcgctg
    19741 acaaatccat ctctgcactc tgaaaatggc gcataaaggc ttggattggc tcatattgcc
    19801 attttgatat gaccttgtcc aagaatttct ttattgacat tctaataagt tctttcttcg
    19861 ccctgactag ttaaaatcac tggaccatcc tttgtaatca caaattgatg ctcatactgg
    19921 caggacaagc caccatcaag tgttttatgg gcccagcctg ttttcatatc tgtattaatt
    19981 tcccatgtgc cagtattgat catcggctct acggtgagca ccatgccctc cttcagacgt
    20041 agtcctcttc ctgctgtacc atagttaggc accatcggct cttcgtgcat ggttggtcca
    20101 acaccatgac caacaaggtc tcgaaccaca ccgtagccat gactttcagc atattgctgg
    20161 actgctgcac caatgtcacc aatgcggttc cccacaactg cctgctcgat cccacgatac
    20221 atggcttcct tggtcacgtc catcagcctt ttgacctcat cagacggtgt acctacagca
    20281 taagcccagc aggaatcagc caaaccacct gtataagatt ctgtccactt cttcatttct
    20341 gccacattat caaaatccaa ggccgctaca tcaacgacag ccttatcaag tggctcactt
    20401 agcaccatat ctaccttaag caaatcccct tcctgtagaa tataatggcg cggaaaagca
    20461 tgtgcaacct catcatttag cccgcagcag gtagcgtaag gataatccat taattggcca
    20521 tcaacaccga tctgtaaagg aagcacattg tcctccttgc agcgcctgcg cacatattct
    20581 tcgacctccc acatgtcaac cccaggctta atgatctgtc tgaggccaat gtgaatccca
    20641 gcaagaaagt ctcctgctct atccatagct tctatttcac gcgcagattt taatgttatc
    20701 attgtttttg tttctcctct aattaagctt agttgtaata atggctttag caatcacctg
    20761 atcatcaacc atgacctcca tatcaagtgt actgcttctt ctattttcag ttataatttt
    20821 agggtatatc ctcaattgat catcaatttg gacagcatgt agaaagtata tcatcatttg
    20881 ctcgataatg atattttttt ggtgtttttt cgttagcact ctgacactga tttcctttaa
    20941 gaattcagca accactccat ttgacagatt gccagcacta tcaatcatgg taggctcaat
    21001 catgacctga taataatcca aggtctcctc aaggcttgat agcatttgct ggctataggt
    21061 gtaaagattt cccggctggt gattcggcag gttttccata gcctgtcgtc tggtaataat
    21121 ccccagcaga aaatgatgat catcaactac tgggagcatg ttcaaatcct caaagatcat
    21181 tttttgacta atattagcca ggctagcatt gggctttgca gtgataggat ttggagacat
    21241 cacctgctca agtctagtct cagcaggctg atccaccaca tcacgcatac tgaccacacc
    21301 aaccacctga tcaagcgcat ctacaattgg aaaccttact tgacctgtct ttttaatcag
    21361 tgcattaaat tcctcgacag tgtctgtctc ataaaggcag ccgtattctt caactggaat
    21421 cagaacctga gcaactgttt ttaaatcagt cttaatgcga atattagaca aggcatggtt
    21481 aatcatcgtt gccactgtaa aggtatcgta atgtgtcacc ataaccggaa taccttggct
    21541 atcagctgtt tcaataacct gcttagacac cggaaagcca cccgtcacta agatagcatt
    21601 gtgattttta agggctaaca gttggatatt ttcacgatcg ccaacaatca aaagccctcc
    21661 tttgatcaaa taacggtgaa tattttgctg ggtcatcgct ccaatagaaa acttgctaaa
    21721 ctcatgtccc aaaccagcat gaccggctaa aacctcagaa tcactgatcc ttgcaatttc
    21781 ggcataggtc aaacggtcaa tacgaacccg tccttttttc tcaatgcgga cagtaccact
    21841 acgcggcttg gtctcaacaa tcccccgatt ttcagcctcc ttgatcgctc tataggcagt
    21901 accatcacta acctttaaat gatttgaaat acttcggacg ctcacacgct ttccaatagc
    21961 aagtctttct aaataatcta aaatgtcttg atgcttactc ataatgatac tcacctatcg
    22021 ttagttgata ttctaaataa tctcgtatgt gatgactatg ccgatcactg cccttaaatt
    22081 gctttgttaa tcgaaagccg gctttttcag caaccctctg gctggccttg ttttccagat
    22141 gtgtcacaat gatcagctgc ctcaagccaa actcctgaaa agctaaaaag gtaagcgtct
    22201 ttaagacctc ggtcattaag ccctgtcccc aaaagggctg cgctaaaaaa tagccaatct
    22261 cagcacttgc ctgctgctta tcatattttt ctagtctaat agagccaagc atgctatggc
    22321 tggtcttatc ctctattaac cagactccca agggctcttt cataaaagca ttgaccatta
    22381 agaaatcact ctcagccttg gtcatgctct ctggaaacac aaactggtaa tggctgttat
    22441 gactgatcat atcataaaac ggctgatgat ctgcatattg aaagggcctc aagagcagtc
    22501 gttgcgtctc aacaaaagca aaccttgcta gctgtgtcca aatatccata gcctcccctt
    22561 caacatgcct gtaatactat tattatagca gatatcacct aaacattcta taactgtcat
    22621 gagttttgcc atgatgatca taataacctg acaagccata tcatagctca atcagactct
    22681 aagctgttaa actattacta acagtcaaaa ccaaaaaaga gaagaccgtc tgatcttctc
    22741 ttgctatctt atctgctaat gcttaaatgg gctacatcat agaaaagtcc tatgagtaag
    22801 ctcatccttc taaggctaaa catgcttcca taaatacact gcttagtcct gctgacgctt
    22861 tgaagtcact gctaaagcac ctgcactcgc cataatggca agagccgctg ctgtaaagaa
    22921 tggattagcc ttctcaccag tcgttggaag agtcttagcc ttttgcttat ctttttgctt
    22981 agctggtgct gtcttagttg ctggtgtaag cggtgtcaac ggaagagaag ctgatggctt
    23041 ttctggatca gctggactct cctctaaagc ctcagtgact gtaaatgtct ttgtagcagc
    23101 gtcataagcc cattcaccag taacgccatt gtcattggca tattgcctga aggtctgctc
    23161 ggctgtggct gcgtctactg ccttggtagc tgtttcacct gagaaggtaa cccccttaat
    23221 aacaagccta taggtggtca aagctggtgt taattctgcc gcctcaatag tctcagctac
    23281 aggctgttca gtgactgtaa atgtctttgt ggcagcatca taagcccaaa cgccgtctac
    23341 accattttta ttagcatagt ctctgaaggt ctgctcagct acagctgcgt ctactgcctt
    23401 agtagctgtt tcacctgaaa aagttgctcc cttgatgaca agcttatagc tagtcaaggc
    23461 tggtgttagt tctgctgcgt caatgacctc agaactcggt agagctgata aaatctctgc
    23521 cttaagcgca ttgacacctt caacagtttt ggctttgttg attaaggtca catagtaatc
    23581 actaatgcca tactgcttta gttcattgat agcagcttct ttagcctcca acaaggctgc
    23641 tcctgtaatg tccgcaatag ctgtatgagc atcattaatg gctgcattca cttgatcaac
    23701 tgaagcagca tctgccacct tagctgctgc agcaactaga gctagctgaa ccttttgatc
    23761 gcttttgtgc tgatcactta aggcattgat tgttctgtaa gcctcacgtc ttgcttcatc
    23821 aagctgaaca ccagcaacag ctgcctttgc tttgtcaaga gctgctttag cctgatcaac
    23881 agtatctgca gcaagtgcct caactccagc attagcaaga acagcctgaa gctcttgatt
    23941 gtcagcgtag tcatcactca gctgattgat ttccctaaca gcttctctaa tgaaggctgt
    24001 tgtaggctct aacactgttg ctgcgtctaa agcacccact gaagtcgttc caaccagaaa
    24061 ggctgccgac actgaagcta aaccaacagc tgattgacgt aaaaagtagg ataccttttt
    24121 gtttttttcc atttttcctc cctcgctttt tgtaaaaaaa actttgacac taaaaactat
    24181 taatgtcact tctatta
//
LOCUS       DARYMD010000033        23470 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYMD010000033 DARYMD010000000
VERSION     DARYMD010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23470
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..641)
                     /locus_tag="TU818_001271"
     CDS             complement(<1..641)
                     /locus_tag="TU818_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000600261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0924087.1"
                     /translation="MILGETYRKMREEKGISISSLAGYEISKSQISRFELGETEISIF
                     KLLYLLEKLGITFEEFLLACNNYEPSEFNTLIKAVQNSAYNNKVETLISMIEQENKLF
                     EETNSHYHKLNSIFIQSIISGLDNNHQLTNQDISYLSNYLFSLENWGYYETLILGNCC
                     RSLPPKLLFKYTKEALKKGKLYNSIPRNKQSLIQLLLNSLLLMIENDFYEEAI"
     gene            1277..2761
                     /locus_tag="TU818_001272"
     CDS             1277..2761
                     /locus_tag="TU818_001272"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL0924088.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFVDVPGT
                     DIIVFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     QQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLVAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     YLLGNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            2801..4102
                     /locus_tag="TU818_001273"
     CDS             2801..4102
                     /locus_tag="TU818_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL0924089.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TATVILVANQLGSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKA
                     QQAGMVVLVFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGV
                     TLNYGVIGVWLATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            4482..4790
                     /gene="rpsJ"
                     /locus_tag="TU818_001274"
     CDS             4482..4790
                     /gene="rpsJ"
                     /locus_tag="TU818_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL0924090.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPFPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            5088..5714
                     /gene="rplC"
                     /locus_tag="TU818_001275"
     CDS             5088..5714
                     /gene="rplC"
                     /locus_tag="TU818_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL0924091.1"
                     /translation="MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            5739..6362
                     /gene="rplD"
                     /locus_tag="TU818_001276"
     CDS             5739..6362
                     /gene="rplD"
                     /locus_tag="TU818_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL0924092.1"
                     /translation="MANVKLFDQTGKEVSTVELNDDIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            6362..6658
                     /locus_tag="TU818_001277"
     CDS             6362..6658
                     /locus_tag="TU818_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL0924093.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAVEAE"
     gene            6676..7509
                     /gene="rplB"
                     /locus_tag="TU818_001278"
     CDS             6676..7509
                     /gene="rplB"
                     /locus_tag="TU818_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL0924094.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLVNIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLLVRRRNE
                     K"
     gene            7621..7899
                     /gene="rpsS"
                     /locus_tag="TU818_001279"
     CDS             7621..7899
                     /gene="rpsS"
                     /locus_tag="TU818_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL0924095.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            7915..8259
                     /gene="rplV"
                     /locus_tag="TU818_001280"
     CDS             7915..8259
                     /gene="rplV"
                     /locus_tag="TU818_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL0924096.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            8272..8925
                     /gene="rpsC"
                     /locus_tag="TU818_001281"
     CDS             8272..8925
                     /gene="rpsC"
                     /locus_tag="TU818_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL0924097.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            8929..9342
                     /gene="rplP"
                     /locus_tag="TU818_001282"
     CDS             8929..9342
                     /gene="rplP"
                     /locus_tag="TU818_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL0924098.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            9352..9558
                     /locus_tag="TU818_001283"
     CDS             9352..9558
                     /locus_tag="TU818_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL0924099.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            9583..9846
                     /gene="rpsQ"
                     /locus_tag="TU818_001284"
     CDS             9583..9846
                     /gene="rpsQ"
                     /locus_tag="TU818_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL0924100.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            9871..10239
                     /gene="rplN"
                     /locus_tag="TU818_001285"
     CDS             9871..10239
                     /gene="rplN"
                     /locus_tag="TU818_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL0924101.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            10323..10628
                     /gene="rplX"
                     /locus_tag="TU818_001286"
     CDS             10323..10628
                     /gene="rplX"
                     /locus_tag="TU818_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL0924102.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            10652..11194
                     /gene="rplE"
                     /locus_tag="TU818_001287"
     CDS             10652..11194
                     /gene="rplE"
                     /locus_tag="TU818_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL0924103.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            11210..11395
                     /locus_tag="TU818_001288"
     CDS             11210..11395
                     /locus_tag="TU818_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL0924104.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            11728..12126
                     /gene="rpsH"
                     /locus_tag="TU818_001289"
     CDS             11728..12126
                     /gene="rpsH"
                     /locus_tag="TU818_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL0924105.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            12448..12984
                     /gene="rplF"
                     /locus_tag="TU818_001290"
     CDS             12448..12984
                     /gene="rplF"
                     /locus_tag="TU818_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL0924106.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            13087..13443
                     /gene="rplR"
                     /locus_tag="TU818_001291"
     CDS             13087..13443
                     /gene="rplR"
                     /locus_tag="TU818_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL0924107.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            13462..13956
                     /gene="rpsE"
                     /locus_tag="TU818_001292"
     CDS             13462..13956
                     /gene="rpsE"
                     /locus_tag="TU818_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL0924108.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            13971..14153
                     /gene="rpmD"
                     /locus_tag="TU818_001293"
     CDS             13971..14153
                     /gene="rpmD"
                     /locus_tag="TU818_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL0924109.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            14355..14795
                     /gene="rplO"
                     /locus_tag="TU818_001294"
     CDS             14355..14795
                     /gene="rplO"
                     /locus_tag="TU818_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL0924110.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            14812..16116
                     /gene="secY"
                     /locus_tag="TU818_001295"
     CDS             14812..16116
                     /gene="secY"
                     /locus_tag="TU818_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL0924111.1"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATIREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            16268..16909
                     /locus_tag="TU818_001296"
     CDS             16268..16909
                     /locus_tag="TU818_001296"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL0924112.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            17027..17245
                     /gene="infA"
                     /locus_tag="TU818_001297"
     CDS             17027..17245
                     /gene="infA"
                     /locus_tag="TU818_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL0924113.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            17271..17387
                     /gene="rpmJ"
                     /locus_tag="TU818_001298"
     CDS             17271..17387
                     /gene="rpmJ"
                     /locus_tag="TU818_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL0924114.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            17405..17770
                     /gene="rpsM"
                     /locus_tag="TU818_001299"
     CDS             17405..17770
                     /gene="rpsM"
                     /locus_tag="TU818_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL0924115.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            17788..18171
                     /gene="rpsK"
                     /locus_tag="TU818_001300"
     CDS             17788..18171
                     /gene="rpsK"
                     /locus_tag="TU818_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL0924116.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            18218..19156
                     /locus_tag="TU818_001301"
     CDS             18218..19156
                     /locus_tag="TU818_001301"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL0924117.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            19171..19557
                     /gene="rplQ"
                     /locus_tag="TU818_001302"
     CDS             19171..19557
                     /gene="rplQ"
                     /locus_tag="TU818_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL0924118.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(19775..20006)
                     /locus_tag="TU818_001303"
                     /pseudo
     CDS             complement(19775..20006)
                     /locus_tag="TU818_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20862..22112
                     /locus_tag="TU818_001304"
     CDS             20862..22112
                     /locus_tag="TU818_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924119.1"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQETLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     YLSDYVYDPDVLSKRAAINHSWIKTGYTMSKNFGKAVSKDYTKASFLSYGKAAKATGW
                     TSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGPIEGAIIGSKAGPWGA
                     LMGFVTGGINVTWGVVHPESKDNMFLWIQDKMDDVYDSIVQTDLGKGTHHAKESVKGH
                     IGRAIVRTWDFVSQSFGKGVGYDI"
     gene            22102..22977
                     /locus_tag="TU818_001305"
                     /pseudo
     CDS             22102..22977
                     /locus_tag="TU818_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677217.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22998..23291
                     /locus_tag="TU818_001306"
     CDS             22998..23291
                     /locus_tag="TU818_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL0924120.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
BASE COUNT         7256 a         4163 c         5155 g         6896 t
ORIGIN      
        1 aatattgctt cttcataaaa atcattttca atcattaata gaagactatt aaggagtagt
       61 tgaattagcg actgtttatt acgaggaatt gaattgtata attttccttt ttttagagct
      121 tccttagtat acttgaataa tagtttagga ggtaaagaac gacagcaatt tccaagaata
      181 agggtttcat agtatcccca attttctaag gaaaataaat aatttgaaag ataagagata
      241 tcttgattag ttaattggtg attgttatca agtccagaaa tgatactttg gataaaaatt
      301 gaatttaatt tatgataatg agagtttgtc tcttcaaaca atttattttc ttgttctatc
      361 atacttatta gtgtttcgac tttattattg tatgcagaat tttgaacagc ttttattagt
      421 gtattaaatt cagatggttc ataattgtta caggcgagca agaattcttc aaaggttatt
      481 ccgagttttt ctagtaaata taataacttg aaaatagaaa tttccgtctc tcctaattca
      541 aatcttgaaa tttgagattt tgaaatttca tatcctgcta atgaagaaat agaaattcct
      601 ttttcttccc gcatttttct ataggtttca cctaagatca tagattatct ccgtttgtag
      661 ttaaaaagtg gaaagcgtga caaatgatga gaaaaagtta caagttactt aaattgattc
      721 ttgatattat cattattata ggtttatgtc aataattttt gtagattgca tgaagtataa
      781 tgcctataag tttttagtac tcaattttat gatttaatat ttaaattaag caatagtcaa
      841 gtcacctttc actaagaaaa atcacttgat tattgcttag ttttttctaa tggaggattt
      901 ttagtttaga agctttgagt ttagacctca aaacttagat atggaattcg aaaggcagtc
      961 actgctgtca acattacttt gggaaagttc ctataagaga cttttcatta gactgaagta
     1021 gcttcaatag ctctaaaact acctagactc aagtaacaac aagtccttag aattgatttt
     1081 ctaagggctt ttttgctgcc tcaaggtaaa gacatgttca gcaacaaatt gactggctag
     1141 accagtcctt tatttatgct gatggcttga gactgctggg ttattagcac agaaaatggc
     1201 tgtctccaaa tcctagaagg cttatgattg gaatatgata taatagtcaa aagaaatgat
     1261 gaggtgatgt gaagcaatgc caatgatgta ccaatcaaca agaaatgcag ctaataaggt
     1321 aacagctagt caagcgattt taagtggcct agcagatgat ggtggcttgt ttactcctac
     1381 aagcatgcca gtgctggatc tagattttga ggagctaaag accaagtcct atcaagaggt
     1441 tgccaagctt attttatcag ccttttttga tgactatact gaagcagaat tagatgcttg
     1501 tatctcttct gcctatgatg ataagtttga tacagcagtg atagcacctc tagctacgtt
     1561 aaaggattat cataatttgg agctatttca tggctcaacc atcgcattta aggacatggc
     1621 tctatctatt ttgccttatc tcttgacaac tgctgctaaa aagcaaggtg tggagcgaaa
     1681 aattgcgatt ttaaccgcta cctcaggtga tactggtaag gcagcaatgg caggctttgt
     1741 tgatgttccg ggaacggata ttattgtctt ttatcctaag tcaggcgtta gcaggattca
     1801 ggagctgcag atgatcacac aggccggtca caatacccat gttgtggcga ttgaaggcaa
     1861 ttttgatgat gctcaaacag aggtcaagcg cctgtttaat gaccctgatt tgcgtgagcg
     1921 gctagcagct caacagatac agctgtcttc ggccaattcg atgaatattg gtcgtttgat
     1981 tcctcaggtt gtctattata tttatgctta tgcccagttg gtaaggcatc agcgacttga
     2041 agctggagag acgattaaca tagtagtgcc gacaggaaat tttggcaatc tactggttgc
     2101 ctactacgcc aaagaaattg gacttcctgt tgccaaattc atctgtgctt ccaatgaaaa
     2161 caatgtcttg acagatttct ttgctagtgg taggtatgat aaaaagcgtc ccttcaaggt
     2221 gactactagt ccatcaatgg atattttggt gtcttcaaat ttagagcgct tggtttttta
     2281 tttactaggc aatgatgccc aaaagacagc agtattaatg aagagcttgg cagaaacagg
     2341 tcagtatcag ctagctgatg cagatcagtc tatccttgat ttatttgcgg caggctttgc
     2401 aacagagcaa gagactgcta aagagatcaa aacgatattt gagtctgatc attatgtgct
     2461 tgacccacat acagctgtag cttcagctgt ttatcgtgct tatcgggagc aatcaggtga
     2521 ctctagaccg actattgttg cgtcaactgc tagtccttat aagtttccgc gggtagttgt
     2581 ggaagctatt agtggtcagc aggttgccag tgattttgag gcgcttgagc agttggctga
     2641 tatatcaggt gtagtcgtgc cacaagcggt caatggctta caggaggcgc ccattcgtca
     2701 tagcctttta gtgacagtag cagatatgca gcaggcagta gaggcttatc ttggagtata
     2761 ggaggcataa aggagctccc tttcaattga tatgaatata atgactcaca atagaaaaaa
     2821 gatactgtcc ttggcccttc catcaatggc agaaaatata ttgcaaatgc tgatgggaat
     2881 gatagacaat tatttggctg ctcaaattgg acttacggct gtttcaggca ttgcgattgc
     2941 taataatatt ctgacgattt atcaggccct ttttatcgca ttaggtgctg cagtctccag
     3001 tctcattgct agaagcgtag gagagcaaaa ccattctaaa gaaatcgact acatggcaaa
     3061 tgctatctta gtaacggggg ctctatcagt tcttctaggc ttgatgtccg tagtgggaca
     3121 taaaagcata ttagcctttc tgggagcagc tagtctggta gctagacttg gtgggcagta
     3181 tttagccatt gtcggtggaa tgattcttag tcttggtctt ttcacgagct taggtgcgat
     3241 tattcgtgct aagggccagc ctagcattcc catgaaggtc agccttttaa ctaatttgct
     3301 aaacgctgta ttttcagccc tttctcttta catatgggga tttggagtga tagggattgc
     3361 ttggtcaact gttgcatcac gtctcattgg agttgttatt ctatgtcact ttcttcctat
     3421 taaagaaatt attaaacgtt ttgctaatcc cttagataaa gagatcttta gcctctctct
     3481 tccagcggct ggtgagcggc tcatgatgcg agctggtgat gtgctgattg ttactattat
     3541 tgttagattt ggaacagagg ccttggcagg caatgcgatt ggagaaacct taactcaatt
     3601 taattatatg ccgggacttg ctatgtcaac tgcgacagtc attttagttg ccaatcagtt
     3661 gggcagtggc aaaggggcta caatagcgaa aactgtaaaa gaaacctttt tgttagccac
     3721 cctgatgatg cttgttatgg gcttgatcac ttatttgcta ggccctaatc tactgccctt
     3781 atttacagca gatgccaagg ctcagcaggc tggtatggtt gtcttagtct tttctctttt
     3841 gggggtacca gcaacagccg ggaccttggt ttatacagca gcctggcagg gtatcggaca
     3901 agctaagctt cccttttatg caacaacgat tggtatgtgg ctggttcgga tttctttggg
     3961 ctactttatt ggagtaacct taaattatgg agtaataggt gtttggcttg cgactatttt
     4021 ggacaatgct accagatggc tcattcttgc agtggctttt aagaagcagc aaaggcagct
     4081 tttttcggac tgtcatagct aaactttgta tttaggtctc aagacttctg agtggtgact
     4141 ttccttttgg gagtcagcca ctgtcatcag aatgtaaagt acgcctgagg ctctgtttgc
     4201 taatagcttc tcttatctgc ggaagatcaa agaggattgc tggaacagct gaggtttgtc
     4261 ttcaatctgg cttgcccttt cttagggcaa gtttttttga aaaaatcccc tgaaaggctt
     4321 gcaatgcctt attaattctg ctattatatt atggtgctgt aaaaatacag ctttagctgt
     4381 gatacgagag gttgcgacac gctcggttgc attgccacgt gacaggtgtc ggttttctcg
     4441 aggagctagc ctattatcgt aaatagacga gaggagaaaa gatggcaaac aaaaaaatcc
     4501 gtatccgctt gaaagcgtac gaacaccgta cacttgatac agcggcagaa aaaatcgttg
     4561 aaactgcaac tcgtacaggt gcaacagtag ctggaccagt tccatttcca actgaacgta
     4621 gtctttacac cattattcgt gcgactcaca agtataaaga ttctcgcgaa caatttgaaa
     4681 tgcgtacaca caaacgtctt attgatattg tgaacccaac gcaaaagact gttgatgcac
     4741 ttatgaaatt ggaccttcca agtggtgtca acgtagaaat caagctttaa ttgtttgaaa
     4801 catgagtgag gaacgagttc atatctaatt gaacacaggc taaactctgt gtgaaaaaga
     4861 gacacagccg ttctaatttt aattagatta cggatgtggc tacctgtagg tgtaaatctt
     4921 cctagaaaca gaagtttctt cgtcagattt cctattttca ctgtgagttt gacgccttaa
     4981 gtatcttgct ttgagcataa aaaacgctcg taaaaaactt ttttgagcat aaaaaacgct
     5041 cactaaaaac tttttgaaat attattaaga aaaggaatta ttttctcatg acaaaaggaa
     5101 tcttagggga aaaagtggga atgactcaaa tcttcactga atccggtgaa tttatccctg
     5161 ttactgtcat cgaagcaact ccaaacgttg tgcttcaagt taagactgtt gaaacagacg
     5221 gttacgaagc aattcaagtt ggttttgatg ataaacgtga agtattgagc aacaaacctg
     5281 ccaaaggcca tgtagcaaaa gctaacacag ctcctaagcg cttcattcgt gaattcaaaa
     5341 acattgaagg cttagaagta ggtgcagaaa tcactgtgga tatcttcgca gctggggatg
     5401 ttgttgatgt aactggtact tcaaaaggta aaggcttcca aggtgttatc aaacgccatg
     5461 gtcaatcacg tggtccgatg gcccatggtt ctcgttacca tcgtcgtcca ggttctatgg
     5521 gacctgtttc accaaaccgc gttttcaaaa acaaacattt ggcaggacgc atgggtggca
     5581 atcgtgtaac tattcaaaat cttgaaattg tacaagttat cccagaaaag aacgttattc
     5641 ttattaaagg taacgtacca ggtgctaaga aatctcttat caccatcaaa tcagcagtta
     5701 aagctgctaa ataataagaa aggagaaaac agttaaaaat ggcaaacgta aaactatttg
     5761 accaaactgg taaagaagtt agcacagttg aattaaatga tgatatcttt ggtatcgaac
     5821 caaacgaatc agttgttttt gatgttgtaa tcagccaacg tgctagcctt cgccaaggta
     5881 ctcatgcggt taaaaaccgt tcagcagtat caggtggtgg acgtaaacct tggcgtcaaa
     5941 aaggaactgg acgtgctcgt caaggttcta tccgctcacc acaatggcgt ggtggtggtg
     6001 ttgtctttgg accaactcca cgttcatatg gatacaaact tccacaaaaa gttcgtcgcc
     6061 ttgctttgaa atcagtttac tcagcaaaag ttgctgaaga taaatttgta gctgtagaaa
     6121 gcctttcatt tgcagcacca aaaacagctg aatttgcaaa ggtgctttca gctcttagca
     6181 ttgatacaaa agtacttgtt cttgttgaag aaggaaatga atttgcagca ctttctgcac
     6241 gtaaccttcc aaacgtagct gtggcaacag cagcgactgc aagtgttctt gatatcgtaa
     6301 acgcagacaa acttcttgta acgaaagaag caatctctac aattgaggag gttcttgcat
     6361 aatgaatttg tacgacgtaa tcaaaaaacc agttattact gaaaaatcaa tgtatgccct
     6421 tgaagaaggt aaatacacat ttgaagttga cacacgtgcg cacaaactgt taatcaagca
     6481 agctgttgaa gctgcatttg acggagttaa ggttgcaagc gtcaatactg ttaacgttaa
     6541 accaaaggct aagcgtgttg gtcgttacac aggttttact tcaaaaacta aaaaggctat
     6601 catcactctt acagctgatt ctaaagcaat cgagttgttc gcagttgaag ctgaataatc
     6661 taaggaggaa ataacgtggg tattaaagtt tataaaccaa cgacaaatgg ccgtcgtaac
     6721 atgacttctt tggatttcgc tgaaatcaca acaagcacac ctgagaaatc attgcttgtt
     6781 tctcttaaaa acaaagctgg tcgtaacaac aatggtcgca ttacagttcg tcaccaaggt
     6841 ggtggacaca aacgccatta ccgtttgatt gacttcaagc gtaacaaaga tggtgttgaa
     6901 gcagttgtta aaacaatcga atacgatcca aaccgtactg caaacattgc acttgtacat
     6961 tacactgacg gagttaaggc ttacatcatc gctcctaagg gtcttgaagt aggtcaacgt
     7021 attgtttctg gaccagatgc agatattaag gttggtaatg cacttccatt agtaaacatt
     7081 cctgttggta cagttgttca caacattgag cttaagcctg gtaagggtgg agagcttgta
     7141 cgtgctgctg gagcttctgc tcaagtactt ggtcaagaag gcaaatacgt tcttgttcgt
     7201 cttcaatcag gtgaagttcg tatgattctt ggaacatgtc gtgcaactgt tggtacagtt
     7261 ggtaacgagc aacaatcact tgttaacatt ggtaaagcag gacgtagccg ttggaaaggt
     7321 atccgcccaa cagttcgtgg ttctgtaatg aaccctaacg atcacccaca tggtggtggt
     7381 gaaggtaaag caccagttgg acgtaaagcg ccatctactc cttggggtaa accagcgctt
     7441 ggtcttaaaa cacgtaacaa aaaagctaaa tctaacaagc ttcttgttcg tcgtcgtaac
     7501 gaaaaataag cggcaaatct agcataagct tattcaatca ttccgccagc tcggtagagt
     7561 ttgagcttgc tctcatgctc aagccgctgt ggtacattat ttaaaggaga aaactacaaa
     7621 atgggacgta gtcttaaaaa aggacctttc gtcgatgagc atttgatgaa aaaagttgaa
     7681 gctcaagcta atgacgaaaa gaaaaaagta atcaaaactt ggtcacgtcg ttcaacgatt
     7741 ttcccaagtt tcatcggata tacaatcgca gtttatgatg gccgcaagca tgtacctgtg
     7801 tacattcaag aagacatggt aggtcacaag cttggtgaat ttgcaccaac tcgtacctac
     7861 aagggtcacg cagctgacga caagaaaaca cgtcgttaat aggaggagga cacaatggca
     7921 gaaattactt cagctaaagc aatggctcgt acagtgcgtg tttcacctcg taaaacacgt
     7981 ttagtacttg atcttatccg cggtaagaaa gttgctgatg caatcgcaat cttaaaattc
     8041 actccaaaca aagcagctcg tgttattgag aaaactctta actcagcaat tgctaacgca
     8101 gaaaataact ttggtttgga aaaagctaac ttggtagtat ctgaaacatt tgcaaacgaa
     8161 ggaccaacaa tgaaacgttt ccgtccacgt gcaaagggct cagcgtcacc aatcaacaag
     8221 cgaacaactc acgttacagt agttgtatca gaaaaataag gaggtaaaat cgtgggtcaa
     8281 aaagtacatc caattggtat gcgtgtcgga atcattcgtg actgggatgc aaaatggtat
     8341 gctgaaaaag aatacgcgga ttaccttcat gaagatcttg caatccgtaa attcattaac
     8401 aaagaattgg cagaggcttc agtttcaaca attgaaattg agcgtgctgt aaataaagtt
     8461 attgtttcac ttcacactgc aaagcctggt atggttatcg gtaaaggtgg agcaaatgtt
     8521 gacgctcttc gcgctcagct taacaaatta actggaaaac aagtacacat caacatcatc
     8581 gaaatcaaac agcctgatct tgatgcccac cttgttggtg aaaacattgc tcgtcagctt
     8641 gagcaacgtg ttgctttccg tcgtgctcaa aaacaagcta ttcaacgtac aatgcgtgct
     8701 ggagctaagg gaatcaaaac tcaagtttca ggtcgcttga acggtgcaga tatcgcgcgt
     8761 agcgaaggct actcagaagg aactgttcct cttcacacac ttcgtgcaga tattgactat
     8821 gcttgggaag aagcagatac tacatacggt aaacttggtg ttaaagtttg gatttatcgt
     8881 ggtgaagttc ttccagctcg caaaaacact aaaggaggca aataacagat gttagtacct
     8941 aaacgtgtta aacaccgtcg tgagtttcgt ggaaaaatgc gcggtgaagc aaaaggtgga
     9001 aaagaagtat cattcggtga atatggtctt caagctacta ctagctcatg gatcactaac
     9061 cgccaaatcg aagctgctcg tatcgctatg actcgttaca tgaagcgtgg tggtaaagtt
     9121 tggattaaaa tcttccctca caaatcttat acagctaaag ctatcggggt tcgtatgggt
     9181 tctggtaagg gtgcacctga aggttgggta gcaccagtta agcgtggcaa ggttatgttt
     9241 gaggttgctg gtgtttctga agaaatcgct cgtgaagcac ttcgtcttgc tagccacaag
     9301 ctaccagtta aatgtaaatt cgtaaaacgt gaagcagaat aaggagaaga catgaaactt
     9361 gaagaaatca aaaagtttgt tgctgagctt cgtggcttgt ctcaagaaga gcttgctaag
     9421 aaagaaaacg aactcaaaaa agaacttttc gaccttcgtt ttcaagctgc agcaggtcaa
     9481 ctagatcaaa ctgctcgttt gaacgaagtt aaaaaacaaa ttgcacgtgt aaagactgtg
     9541 caatctgaaa tgaaataata gattgggaaa ggagtattct aaataatgga acgtaatcaa
     9601 cgtaaaaccc ttgttggacg tgttgtatct gacaagatgg acaaaacaat cactgttata
     9661 gttgaaacaa agcgtaacca cccagtctat ggtaaacgta tcaactattc taaaaaatac
     9721 aaagcacatg acgaaaagaa ccttgctaaa gaaggcgata tcgttcgtat catggaaact
     9781 cgtccacttt cagctacaaa acgcttccgt cttgtagaaa tcgtggaaga agctgttatt
     9841 atctaatcaa actaaaagga gacaattgaa atgattcaac aagaaactcg cttgaaagtt
     9901 gctgataata gcggtgctcg tgagatcttg actatcaagg ttcttggtgg ttcagggcgt
     9961 aagtttgcta acatcggtga cgtcatcgtt gcatctgtaa aacaagctac tcctggtgga
    10021 gcagttaaaa agggtgatgt tgttaaggct gttattgttc gtacaaagag tggtgctcgt
    10081 cgtccagacg gttcatacat caaatttgat gacaatgcgg ctgtcattat tcgtgatgac
    10141 aagactcctc gtgggactcg tatctttggg cctgttgcac gtgaattgcg tgagggtggc
    10201 tacatgaaga tcgtatcact tgcaccagaa gtactttaat tttaatcatt aaacaaacta
    10261 agtcccctag gctagcctag ggtgcccata ggggcgtaag aaaataatag gagaaaccca
    10321 taatgtttgt aaaaaaaggc gacaaggttc gcgttattgc tggtaaggac aaaggtgttg
    10381 aagctgttgt tcttaaagca cttccaaaag taaacaaagt tattgttgaa ggcgtagcca
    10441 tcatcaaaaa gcatcaaaaa ccaaacagcg aaaatcctca aggtgctatc gttgaaaaag
    10501 aagcaccaat ccatgcatca aacgttcaag ttcttgataa aaatggtgtt gctggacgcg
    10561 ttggttacaa gtttgtagac ggcaaaaaag ttcgttacaa caaaaaatca ggcgaagtgc
    10621 ttgattaatc acgaaggaaa ggagaagcat aatggcaaat cgtttaaaag aaaaatatac
    10681 taacgaagta attcctgcgt tgacagagaa gtttaattac acatcagtta tggctgtgcc
    10741 aaaggttgag aaaatcgttc ttaacatggg tgtgggtgac gctgtatcaa acgctaaaaa
    10801 ccttgaaaaa gctgctgcag aattggcgct tatctcaggt caaaaaccac ttattactaa
    10861 agctaagaaa tcaatcgctg gcttccgtct tcgtgaaggt gttgctatcg gtgcgaaggt
    10921 gacacttcgt ggcgaacgca tgtacgaatt cctagacaag ctagttagcg tttcacttcc
    10981 tcgtgttcgt gacttccatg gtgttccaac aaaatcattt gatggtcgtg gtaactacac
    11041 tcttggtgtg aaagaacagc ttatcttccc agaaatcaac tttgatgatg ttgataaagt
    11101 gcgtggtctt gatattgtta tcgtaacaac tgctaacact gacgaagaat cacgtgaatt
    11161 gcttaaaggt cttggaatgc cttttgcaaa ataatagggg gtaactaaat tggctaaaaa
    11221 atctatgatt gctaaaaaca aacgtcctgc gaagtattct acacaagctt acactcgttg
    11281 tgaaaaatgt ggacgtccac attctgttta ccgcaagttt aagctttgcc gcgtttgctt
    11341 ccgcgagttg gcttacaaag gccaaatccc aggtgttgtt aaagcgtctt ggtaaaatga
    11401 tgatgtgaga gcgttaagct acctaagcaa aaataggaaa attgacgaag agtctaaata
    11461 ctctaggaaa ttttgcacct aaaggtagta gcttgaactc agttcaaatg aacaaataat
    11521 actatcagat attatgtctg attcgatgca aaggcaaagt gtcaatttga acacgggcga
    11581 aagccggtgt caaaaagata aacattcctt ggaggttttc cctcctgcgg aagtttccta
    11641 ttttgacttt ggcttttagc gccctttgta tcatcgatta actagcaagt gcagcttgca
    11701 aactactagt aagaggagaa taataaaatg gttatgactg acccaattgc agactttttg
    11761 acacgtattc gtaatgctaa tcaagtaaag catgaagtgt tagaagtacc tgcatcaaat
    11821 attaaaaaag ggattgcaga aatccttaag cgtgaaggct ttatcaaaaa cgttgaagtt
    11881 attgaagatg gcaaacaagg aattattcgc gtatttctta agtacggtca aaatggtgaa
    11941 cgtgtcatca ctaacttaaa acgtgtttca aaaccaggtc ttcgtattta ttctaagcgt
    12001 gaggatgttc caaaggttct taatggacta ggaattgcaa ttatttcaac ttcagaaggt
    12061 cttttgactg ataaagaagc tcgtcaaaag aacgttggtg gagaagttat cgcatacgtt
    12121 tggtaattta agagacaaaa gccgtaacga acaatctaaa attagaaaat tattgtggct
    12181 tgcttgcaaa caaaatagtt tgtctatttt agatggcagt tcgtcggctg tgctcaaatg
    12241 atgaacacta tcaacatagc aaacgtaaaa gaactaattg aacatgggct aaagtctgtg
    12301 tgaaaaagat aaatttttct agaaaccttg gtttcatagt aatgtttcct attttcactt
    12361 tgccttttac gccctaagta tcttagttca ccccgtgaaa actcgtcgcg taagcggcct
    12421 gataatttaa caggagaaaa aattaatatg tcacgtattg gtaataaggt tattattatc
    12481 cctgcaggcg ttgaaatcat taacaacgac aatgttgtta ctgtaaaggg gcctaaagga
    12541 gagctcactc gtgagtttaa caaaaatatt gaaatcaaag tcgaaggaaa cgaaatgact
    12601 cttgtacgtc ctgacgactc aaaagaaatg aaaacaattc atggtacaac tcgtgcaaac
    12661 ttgaataaca tggttgttgg agtttcagaa ggtttcaaaa aagagcttga aatgaagggt
    12721 gtcggatatc gtgcacagct tcaaggctct aagcttgttc tttcagtagg taaatctcac
    12781 caagatgagg tggaagctcc agaagggatt acatttactg tagctaatcc aacatcaatt
    12841 tcagttgagg gtatcaacaa agaagttgtt ggtcaaactg ccgcttacat tcgtagccta
    12901 cgttcaccag agccttacaa aggtaaaggt attcgttacg ttggtgagta tgtacgcctt
    12961 aaagaaggta aaacaggtaa ataatgttct tagtggaata tggcataggc ttgcttatgt
    13021 catgctctac aagctcaatt gataatttgt cggaaagaca aacttaaata ttaagaggtg
    13081 aaaattgtga tttcgaaacc agataaaaac aaaatccgcc aaaaacgcca tcgtcgcgtt
    13141 cgcggtaaac tctctggaac tgctgatcgc ccacgtttga acgtattccg ttctaataca
    13201 ggcatctacg ctcaagttat tgatgacgta gcgggtgtaa cgctcgcaag tgcatcaact
    13261 cttgataaag aagtttctaa aggaacaaaa actgaacaag ctgttgtagt cggcaaactt
    13321 gttgctgaac gtgcggtggc taaaggtatt tctgaagtgg tgtttgaccg cggtggatat
    13381 ctctatcatg gacgtgttaa agctttggct gatgcagctc gtgaaaacgg attgaaattc
    13441 taatagggag gacacaaaat aatggcattt aaagataatg cagttgaact tgaagaacgc
    13501 gttgttgcta ttaaccgcgt tacaaaagtt gttaaaggtg gacgtcgtct tcgttttgca
    13561 gctcttgtag ttgttggtga tggaaacgga catgttggat tcggtactgg taaagctcag
    13621 gaagtaccag aagctattcg caaggcagtt gaagctgcta aaaagagcat gattgaagtg
    13681 ccaatggttg gcacaacaat tcctcacgag gtttacacta actttggtgg agctaaagta
    13741 ttgttgaagc cagctgtaga aggttctgga gttgctgctg gtggtgcggt acgtgccgtc
    13801 atcgaattag caggtattgc tgatattact tcaaaatctc ttggttcaaa cactccaatc
    13861 aacatcgttc gtgcaactgt tgaaggatta aaacagctta aacgtgcaga agaagttgcc
    13921 gcacttcgtg gcatctcagt ttctgactta gcttaagaaa ggggatcatc atggctcaaa
    13981 ttaaaattac tttgactaag tctccaatcg gacgtaagcc agaacaacgt aaaacggttg
    14041 ttgcccttgg acttggtaaa ttaaactctt cagttatcaa ggaagataat gctgctattc
    14101 gtggtatggt gacagcaatt tctcacttgg tgacagttga agatgtcaaa taaagagtta
    14161 gctagaaatc tctgatttct tgcattagca tgcagaaccg gcttttgtga gttattcctt
    14221 tgaatgacaa gcagtggtcg gttggtgcat atagcatcag gctatgacat agcttgatca
    14281 tgtataggcg agtttctatg gagagtcctt tcccttcata gaggcgctag cattttacaa
    14341 aaaaaggaga aaaaatgaaa cttcatgaat tgaagcctgc caaaggctct cgtaaagtcc
    14401 gcaatcgtgt tggacgcggt acttcatcag gcaatggtaa aacatctgga cgcggtcaaa
    14461 aaggtcaaaa ggctcgtagt ggtggtggcg tacgtctagg ctttgaaggt ggacaaacac
    14521 ccttgttccg tcgtattcca aagcgtggat ttacaaatat caacactaaa gagtatgctc
    14581 ttgttaacct tgatcaatta aacgcttttg aagatggcac agaagtaact ccagttgttc
    14641 ttaaggaagc tggaatcgtt cgtgctgaaa agtcaggcgt taaaattctt ggtaacggcg
    14701 aattgactaa aaaattgact gttaaagcag cgaaattttc aaaatctgct gaagcagcca
    14761 ttactgctaa gggtggttca atagaagtca tctaatgagg ggatactcat tatgttctta
    14821 aaaatactca aagacgcatt gaagataaag aatgttagaa ataaaatatt ttttacaatc
    14881 tttattatcc ttatattccg tattggaaca catatcactg ttcctggtgt aaatgcaaaa
    14941 agcttagagc agctgagtga gcttcccttc ctaaatatgt tgaacttggt cagcggtaat
    15001 gcaatgagaa acttttcagt tttctcaatg ggtgttagtc cctatattac agcctcaatc
    15061 gttgttcagc tattgcagat ggatattttg ccgaagtttg ttgagtgggg aaaacaaggt
    15121 gaggttggcc gtcgtaagct aaaccaagcg acgcgctata tttcccttgt cttagccttt
    15181 gctcaatcta tcggtattac agcgggtttt aacaccttat caagtgtggc cctagtcaaa
    15241 acaccagatg taagaaccta tttactgatt ggagctttac tgacaacagg tagtgtgatt
    15301 gtgacctggc ttggtgaaca gattaccgat aaaggctttg gtaatggggt gtctatgatt
    15361 atctttgcag gtatcatttc ctctattcca aatgctattg caaccattcg tgaggattat
    15421 tttgtcaatg tgaagtcagg tgacctacag tcatcttata tcgttgttgg tattctcatt
    15481 cttgcagtgc ttgctatcgt ctttttcaca acgtatgttc agcaggcgga atataaaatt
    15541 ccaatccaat atacaaagct tgttcagggt gcgcctacaa gctcatacct tcccttaaaa
    15601 gtaaatccag ctggtgttat tcccgttatc tttgccagct cgattacaac aattccaagt
    15661 acgattatcc cgttctttca aaatggcaga gatattccat ggttgacaac tttgcaagga
    15721 atttttaact atcaatctcc aacaggaatg attgtttatg ccttgttaat tatcctgttt
    15781 tcattcttct atacctttgt tcaagtaaat cctgagaaaa cagctgaaaa tctacagaag
    15841 aattcgtcct atattccaag tgttagacct ggacgagaaa cagaagaatt tatgtcatcc
    15901 ttgctaaaga aattggcaac tgtgggtgct atcttcctag catttatatc tcttgttcca
    15961 attgcggcac aacaagctct taacctatct tctagtattg cattaggtgg aactagcttg
    16021 ctgattttga tttcgacagg tatcgaaggt atgaagcagc ttgaaggtta ccttctcaag
    16081 agaaaatatg tcggatttat gaatattaca gaatagaata tgggttgaca ctgtcaacct
    16141 tctattttgt ttttaaatga caataagatt tacagagcct tggttcctat cttcttattg
    16201 ccatttgaaa acaaaaacaa ggaaaactaa atttcctatt atctttatgt caaaagagga
    16261 gaaaaagatg aatcttttaa tcatgggctt acctggtgcc ggtaagggta cacaggctgc
    16321 aaagattgtt gaaacctttg agcttattca tatttcaaca ggagatatgt tccgcgctgc
    16381 aatggctaat cagactgaaa tgggagttct tgcgaaatct tatatcgata agggtgattt
    16441 ggtgccagat gaggtaacca atggtatcgt taaagaacgc ttagcacaag ctgatattaa
    16501 agaaaaggga tttcttttag atggctatcc tcgtaccatt gagcaggcac atgccttaga
    16561 tgaaacctta aaagcattgg gacttacgtt agatggtgtg atcaacattg aggttgaccc
    16621 tgcgtcactc attgacaggc ttagcggtcg tatcatcaac aaaaaaacag gggaaacctt
    16681 ccataagatc tttaacccac cagtgggaga ctataaggaa gaggactttt atcaacgtga
    16741 agatgataag cctgaaacag ttaagcgtcg cttagatgtt aatattgcac aaggtgagcc
    16801 tattatcaag cattatcgtc aagcaggcat tgttcgtgac attgacggaa acaaggacat
    16861 ttctgaggtc tttgctgaca taaaaaaggt catcgaaaac ctgaaataaa ttccagaaaa
    16921 tcgcttgcga aagtgatttt atcgtgatat actagactag tctgacttat aattgttacc
    16981 tctgtgctca gaggacatca aatcgaaatt tagggggtac ttttgcgtgg caaaagaaga
    17041 cgtgattgaa attgaaggta aagttgtcga aactatgcca aatgcaatgt ttactgttga
    17101 attggaaaat ggacatcaga ttttagcaac cgtatcagga aagatccgca aaaattacat
    17161 tcgtatttta gtgggtgatc gtgttactgt agagatgagt ccttacgact tgacacgtgg
    17221 acgtatcaca taccgcttta aatagtcgaa ataattggag ggattaaaac atgaaggtaa
    17281 gaccatcggt taaaccaatt tgcgaatact gcaaggttat tcgtcgtaac ggtcgtgtta
    17341 tggtaatttg tccgacaaat ccaaaacaca agcaacgtca aggataagat agaaaggaga
    17401 aaaaatggct cgtattgctg gagttgatat tccaaatgat aagcgtgtag taatttcact
    17461 tacctatgtg tatggaattg gtcttgcaac atctaaaaaa atcttagcag cagcaggtgt
    17521 ctctgaggac attcgtgtta aagatttgac atcagatcaa gaagacgcta tccgtcgcga
    17581 agtggataca attaaagttg aaggtgatct tcgtcgtgaa gtaaacctaa atatcaagcg
    17641 tttgatggaa atcggttcat atcgtggaat tcgtcaccgt cgtggacttc ctgtacgtgg
    17701 acaaaacaca aaaaacaatg ctcgtactcg taaaggtaaa gctgttgcga ttgcaggtaa
    17761 gaaaaaataa aataggaggt aaaaaaattg gctaaaccaa cacgtaagcg tcgtgtgaaa
    17821 aagaacatcg aatctggtgt tgcacatatt cacgctacat ttaataacac tattgttatg
    17881 attacagatg tgcacggtaa tgctttagca tggtcatcag ccggtgctct tggttttaag
    17941 ggttctcgta agtcaactcc ttttgctgct caaatggctg cagaggctgc tgcgaaatct
    18001 gcacaagaac atggtttaaa aactgttgaa gttactgtaa aaggtcctgg ttcaggtcgt
    18061 gaatcagcta ttcgtgccct agctgctgcc ggtcttgaag taactgccat tcgtgatgtg
    18121 actcctgtac cgcataatgg tgctcgtcct ccaaaacgtc gtcgtgtata atcacagtaa
    18181 caaatagtac acaagtttcg tttcgagggg tgaaagaatg attgagtttg aaaaaccaat
    18241 aataacaaaa attgatgaaa ataaagatta cggtagattt gtaatcgaac cacttgaacg
    18301 tggatatggt acaactctag gtaattcact tcgtcgtgta ctcttgtctt cacttccagg
    18361 tgcagctgtt acatcaatca gaattgatgg agtactacac gaatttgata caatcccagg
    18421 tgtacgtgaa gatgtcatgc aaattatcct taatgttaag ggacttgctg tgaaatcata
    18481 cgtcgaagac gaaaagatta tcgagcttga tgtagaaggt ccagcagagg taacagctgg
    18541 agatattctc acagatagcg atatcgaact tgttaaccct gatcattatc tttttactat
    18601 tgctgatggt tatacattga aggcttcaat gactgtcgct aaaaaacgcg gctatgtacc
    18661 agcagagggt aataaaaaag atgatgcacc tgtggggacg ttggcagtag attcaatcta
    18721 tacgccagta aaaaaggtta attatcaagt tgagcctgct cgtgtaggta gtaatgacgg
    18781 ctttgataaa ttgactattg aaatcatgac aaacggaaca attattcccg aagatgcctt
    18841 aggtttatct gctcgagttt taatcgaaca cttgaattta tttactgatt taacagatgt
    18901 tgcaaaggca actgaagtga tgaaggaagc tgaaaaagtg aacgatgaaa aggtacttga
    18961 tcgcactatt gaggaacttg atttgtccgt acgctcatat aactgcttga aacgtgccgg
    19021 tattaatact gtcttcgatt taacagaaaa atctgagcct gaaatgatga aggtccgtaa
    19081 ccttggacgt aagagtcttg aggaagtaaa ggtcaagctt gctgacttag gtttgggact
    19141 aaaaaacgat aaataacata ggaggataaa atggcttacc gtaaactagg acgcactagc
    19201 tcacaacgta aagcaatgct tcgtgactta acgacagatc ttttgattaa cgaatcaatt
    19261 gtaacgacag aagcacgtgc aaaggaaatc cgtaaaacag ttgaaaaaat gattactctt
    19321 ggtaaacgtg gtgatcttca tgctcgtcgc caagcagctg catacgttcg taacgaaatc
    19381 gcatcagaaa actatgatga agctactgat aaatacacat caacaacagc tcttcaaaaa
    19441 cttttctctg aaattgcgcc tcgttatgca gaacgcaacg gtggatacac tcgtatcctt
    19501 aaaacagaac cacgccgcgg agatgctgct ccaatggcga ttattgaatt agtttaattt
    19561 ttatcaattt tgttgagtgt tatgatgatg gagcagttcc tttaagctgt tcttagtcta
    19621 gctctggtct accgctagga cctttcctag cggtaacact caccatgttg agaataagta
    19681 acgcttgttt acgaaaggtc tctaagctgt aggtgccctt cgtaagcagg cgttttgttg
    19741 tgactccatg ttaactgtag tagatgacta atatctaata tctagagagg atcagcttgg
    19801 tgctctcttt tctgatatta aaagcattgg gaatcttggt tttgaagttc ttaaagctcc
    19861 taaagccaaa gtctttcgct tgatgtcttt ggtcatcttg ttagtggtct ccggcttagc
    19921 attggaataa ggtagttcaa agcattggtg atgtaagatc tatacttcct gaaggtcttg
    19981 aaaaccgttt tgaaggtgtg attgacctgt agcgggagta gattagatca atggcgtttg
    20041 gctgctttga aaatttaggt gacaattgtt tttgtatctt tgtttaaaaa tggtataata
    20101 ttaaaacatt aaacaaaatg tacataaaaa agccatataa aagaatgata ttaagataat
    20161 gtgatcaata gttttagaaa atgaatgtgt aaggttaagg tatgccccct tgatataatg
    20221 ctagttttac gaagaggcat tctgtacaga cataatgcac tcttacaaat gatacggtaa
    20281 ttgctcaaca aggcgcaaca gccttggcaa atgtaatatt tgccttagct agcagcgaat
    20341 tagttacgct tgatacatag acaagggttt ctggcataca gcagcagatg gtgtgcctgt
    20401 ctcagagagt ggctgcttgg cttatcctat tcatgtttta aaacttacag gaggtgttat
    20461 gtggcctttg gtcgatggat atttagctag gtgaacagct attagctgta aatatgaggt
    20521 aggagcttta gtttgcatga tgttaaatga attgaaacag acttaggaaa gcttggctta
    20581 gcaactatca cgcaagttct taacaacgat aaagatcgta tgggaaaata tgatcaagca
    20641 tcaacggaca tgagatgtgt tttatgaaga aaccattata cttttataag acttatttag
    20701 ttgtttttct ttgcggactt gtttgaggag tagtctacat aggcaatagg ctcaggctta
    20761 cagcacttag gagacattag agcatgagaa gcactaactg gctagtgata gaaaagtaat
    20821 agcacagtgt ttttataact aacaagagga gtagacattc tatgagtatt gacatgtatt
    20881 tgagcttatc tgaagagcag gcacagagtg tagaggctgt cttagctagg cgacaaacag
    20941 cctatcaatc cttacaggag accttgatcc aattgatttc taacagtcct gatttatcag
    21001 ggcggaccta tgattctgct aaggcttata gtagtcaagt gctaattcct ttgttaaagg
    21061 ggtgtatgct tttagatgag gcgattataa cagcctgtaa gaggctacct agtgagtacc
    21121 gtagtcaggt agaccaaatt gatttgaagg agagtgatct ggttgagcgt attgcccagt
    21181 tcgatcatgt gattggtcgg tacatggatt tgattagtat tgaatacagt agagaggagc
    21241 ctagctattc ttatatctct catttaagat cagctgagca gctccatcgg gccgttaagc
    21301 ggcgtcttga ggagatattg cgaaggctaa ggcattttga taccaactca gttcaccttt
    21361 tttcgactat tcagactttg gcagcagcgg tacaaatagg catgcgtcaa gctaggacct
    21421 cgtggcatgc aggaagtcag gtatttgtga tttcagagga tatggcatgg gccgatacga
    21481 ttaattctaa gtggtcaaaa agtaaagggt taagctatct tagtgattat gtttacgacc
    21541 cagatgtgct ctctaagaga gcagctatta atcactcttg gattaaaaca ggctatacta
    21601 tgtctaaaaa ttttggcaaa gctgtttcaa aagattatac aaaagcaagc tttttgagct
    21661 atggtaaggc agccaaggcg actggctgga cttctatggc agtagatact ggaataacta
    21721 gtgtaaggga atacaataag aaaaatagta gagcctatgg cagtgagggc aaggcgctta
    21781 ttcatgctag tgtggctcaa atcaagagca tgggacctat agaaggggcg ataattggca
    21841 gtaaagctgg accttgggga gcattaatgg ggtttgttac aggaggcatt aatgttactt
    21901 ggggagtagt gcatccagag tctaaggaca acatgttttt atggatacaa gataaaatgg
    21961 atgatgttta cgattcgatt gttcagacag atcttggcaa agggacgcac catgctaaag
    22021 aaagtgtcaa aggtcatatc ggtcgagcta ttgtaaggac atgggacttt gtcagtcaat
    22081 catttggtaa aggagtgggc tatgacattt aaagatcagc tttttagtgg gacgtttgag
    22141 caatcaaaaa agattgtgtc taaaagtata ttgacagaag aaggtgcgca gattggagta
    22201 ttctcatcta tgagtctatg gaagagaata acaggcttga tgatgttgcc attatttgct
    22261 atttcatatg gagtaggagt tgtgttacct gaacactttc aataatcaac agaaggagtt
    22321 caagctattt cattggctgc aatagagatt attgccagat taggacagtt cagtcgatac
    22381 tttatcattt gttttatttg tatgtctgtt ggattaatta ttagtaatat ccttccaaag
    22441 cctaactagg cttatcaatt attatatggc aatgctactc ttattatact tagtattaca
    22501 actattatct cagccttccc tttaactgct ggccttacaa ttgcagcttt tggctggatc
    22561 ggttttttgc ttcagctatt gctttgcctt tatttgtgga aggtttgtgt catagataag
    22621 tgtcaacagc tacgcacagc aatttatcaa gaaagcacca tagcacctga ttggggcagt
    22681 aagctagtaa gctttattaa gtcttatggt ggtatcttat taggcctctc tgttctcaac
    22741 cgctggactc tcaatctagg agagctagtc aaggaaagcc ctggtttgtt gagttttctg
    22801 tacggctgga tttttctatt gttcatgttt ttgatgctat ttgcactggg tcaagcgtta
    22861 aaaaatacca tcatagccta ttattttttt agatatcaaa aagaataccg caagcatttt
    22921 aatataagcg atgagcagtg gtacggtaaa tggcgtttaa aaatattatt aaaataaacg
    22981 atataaggag taatcatatg caaaaagaat tattaccgtt aggaagtgtt gtctatctag
    23041 agggagcaac aagcaagcta atgattgtcg gacgtggtcc tatatttgaa tctaatggcc
    23101 aaaatgtcta cagtgattat gttggagtaa tgtatccaga agggatcaat ccagaagacg
    23161 cgattttttt caaccatgaa gatattgcaa aaacagtctt tgaaggcttc aaggacgaag
    23221 aagaacaacg ctttttagaa gtgtattctg attgggagag tactttagaa atttccaaaa
    23281 taaagctata gatgaactgt agcagatata tttgtcagta gattgtcatg attatattga
    23341 aagattatga ctttctctgg cttaaatacc tctaaagttc caaagtttag aaaaggcttt
    23401 aaaatgagtg ttataatagc atttatgctc attaaataaa ggtagcattt caatagaatc
    23461 ggtaaaaaaa
//
LOCUS       DARYMD010000034        21156 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYMD010000034 DARYMD010000000
VERSION     DARYMD010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21156
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(171..461)
                     /locus_tag="TU818_001307"
     CDS             complement(171..461)
                     /locus_tag="TU818_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924121.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            complement(442..834)
                     /locus_tag="TU818_001308"
     CDS             complement(442..834)
                     /locus_tag="TU818_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924122.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKGYQKREDSLSERRH
                     VLDDLINSEYQKMSVFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQRETELLDMRRAYANTNN"
     gene            complement(816..2105)
                     /locus_tag="TU818_001309"
     CDS             complement(816..2105)
                     /locus_tag="TU818_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924123.1"
                     /translation="MMISDSSYKKLSEQVYNVEPSKAKSNDAPIVLKGNRLIDDKTGK
                     QYRVLLVQDNNNDAHKINDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNLDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKRMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKVAREGADEALDHK
                     TVADAKLMEVWSAIDFNAFHELPYYEVQALFASYGITYDRFVRDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDQQLAGEFRAWQTEL"
     gene            complement(2107..2538)
                     /locus_tag="TU818_001310"
     CDS             complement(2107..2538)
                     /locus_tag="TU818_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924124.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKRTEEQQKKDLETSIAKL
                     LVHDYEDVKEVKFTGWGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGRSYHPD
                     TFKLVEKNSLEEMGPVKYRIKDIEKVSLEGVSITYSREKRS"
     gene            2877..2963
                     /locus_tag="TU818_001311"
     CDS             2877..2963
                     /locus_tag="TU818_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0924125.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
     gene            complement(3311..5752)
                     /locus_tag="TU818_001312"
     CDS             complement(3311..5752)
                     /locus_tag="TU818_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL0924126.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVIN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLVKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGCKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(5752..6213)
                     /locus_tag="TU818_001313"
     CDS             complement(5752..6213)
                     /locus_tag="TU818_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL0924127.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDCLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAVASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            complement(6383..6586)
                     /locus_tag="TU818_001314"
     CDS             complement(6383..6586)
                     /locus_tag="TU818_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL0924128.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
     gene            complement(6799..6869)
                     /locus_tag="TU818_001315"
     tRNA            complement(6799..6869)
                     /locus_tag="TU818_001315"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6835..6837),aa:Cys,seq:gca)
     gene            7217..7777
                     /gene="ahpC"
                     /locus_tag="TU818_001316"
     CDS             7217..7777
                     /gene="ahpC"
                     /locus_tag="TU818_001316"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL0924129.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYEILKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            7798..9330
                     /gene="ahpF"
                     /locus_tag="TU818_001317"
     CDS             7798..9330
                     /gene="ahpF"
                     /locus_tag="TU818_001317"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL0924130.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITVEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            9791..10561
                     /gene="rpsB"
                     /locus_tag="TU818_001318"
     CDS             9791..10561
                     /gene="rpsB"
                     /locus_tag="TU818_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL0924131.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            10729..11769
                     /locus_tag="TU818_001319"
     CDS             10729..11769
                     /locus_tag="TU818_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL0924132.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(11969..13864)
                     /locus_tag="TU818_001320"
     CDS             complement(11969..13864)
                     /locus_tag="TU818_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL0924133.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEVKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDNIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHAYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(14416..15348)
                     /locus_tag="TU818_001321"
     CDS             complement(14416..15348)
                     /locus_tag="TU818_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL0924134.1"
                     /translation="MTRASQEMRHVYRDFLIAANQEHPEVVVLEADLSSSMATNHLDQ
                     VFGKRYINVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFLSLAYAQLGA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSNGYCLLRQGKDLVLACSGIMVKRCLEVADKMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLRILAAD"
     gene            complement(15345..16202)
                     /locus_tag="TU818_001322"
     CDS             complement(15345..16202)
                     /locus_tag="TU818_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL0924135.1"
                     /translation="MVLSDEPLTDVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFVQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYAIVGDGELNEGQCW
                     EAIQLAAHQQLSHFIVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRALQASSSHKPKCIVLDTVKGQGVSQLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            complement(16205..17548)
                     /locus_tag="TU818_001323"
     CDS             complement(16205..17548)
                     /locus_tag="TU818_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL0924136.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIAYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            complement(17561..17848)
                     /locus_tag="TU818_001324"
     CDS             complement(17561..17848)
                     /locus_tag="TU818_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0924137.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAEHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            complement(17850..19892)
                     /locus_tag="TU818_001325"
     CDS             complement(17850..19892)
                     /locus_tag="TU818_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL0924138.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELDATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELKYTRASGYILVGDEINKHRLA
                     LVMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQVCLY
                     AVIFILCRYQRRVDRVKQRQVVVSEQLDQLTALLVAEIMQQLSLKYQLFEADEAYFQL
                     LLAGCFEGEGTVGDDFFESLTVAIVDQMQGVALLSFSQADQLKENLKRHLIPAYYRLR
                     YGLPSDNDYTLRIKDSYSELFDLVKQSLEPLAKELGSPIPDSEIAYFVLHFGGYLKQQ
                     GRDFHRQAYQAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDKSGYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQGVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGTFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
     gene            20415..21005
                     /locus_tag="TU818_001326"
     CDS             20415..21005
                     /locus_tag="TU818_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924139.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTKIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLR
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
BASE COUNT         6359 a         4835 c         4044 g         5918 t
ORIGIN      
        1 tcagtacact ggtcctctct cgtctttagc tatcggtcac tctgtataca attatcccct
       61 tttaaaaata acaggacaaa agctctggag gctgatcgcc ttttttgatc atacttgctt
      121 ggtaggtatt gattgaaccc ctacggtctc ttataaatga caccatttga ctatagcttg
      181 ttgtattttg gcagcttctt ctttacgacc tgctccagct gatctctgac cgctcctttt
      241 atggccgtat ctagctgccc ttccatgatc tgaaggcttt ccttagtttg gctggcagtc
      301 gctttgatct ggtctttaaa cgtttttttg atcgcttcac cttggctgtt cgcaagccta
      361 gccactgtgg caatcctttg acgctccagc atttgacgca ttagcctcag ggcataggcg
      421 tattcttctt cgatataata ctcagttatt ggtattagca taagctctcc tcatatctaa
      481 taactctgtc tctctttgat cctgctcttg acgaaaagtc ttggttgact gtgctcgctc
      541 ctcttcaaga gctgcccgct ggaggtgaaa ctctgcgttg gattgatcct ttaagcgatc
      601 tagttccttg aaaaaatctg acgcagcatt ggcagatagg tctaaacgct tcaaaaaaac
      661 actcatcttc tggtactcag agttgatcaa atcatctaag acatgtcttc tttcggataa
      721 gctgtcttca cgcttctgat agcctttttt ctggcgcaga aagtcctgct cggcatcatc
      781 catctcccgc agcttacgat agatagccac ttcctctaca attctgtctg ccatgctcta
      841 aactctcctg ctaactgttg atccgtttca agcttgctat caataactgt ctgaatatct
      901 ctattcaggt tttcaaagtc tgtggccaag gctgacagct tgctgacctt ggattgagta
      961 tagtcctgaa agtctcggac gaagcggtca taagtgatcc cataagaagc aaacaaggct
     1021 tgcacctcat aatagggcag ctcatgaaaa gcgttaaaat caatcgccga ccacacttcc
     1081 ataagctttg cgtcggcaac cgttttatga tccagtgcct catcagcccc ctctcgagca
     1141 accttagcca tggacgagcc taggatcatt ccctgtgccg catctaaaaa gagctcctca
     1201 gaactactga tccccttacc ggtagactgc cagtgttttt tgagctgatt gtagcttgac
     1261 atacgctttt ttgaggcaag gacagttaaa taggcccgac tcacaaggta ttgtgttcca
     1321 atgagcttac cgtctctatc tacaatctga cccttttgat taaaacgata agctcctaaa
     1381 tcgtgataat acaaggggtt ggctgataag agcatagcat cgacattccg agaaatagcc
     1441 aaatcatcag ttccaaaata ggcaccaaaa ttgccaatgc catcaaaatt aatgcggaaa
     1501 ttattgtaca tattgctatt agccttaacc catgtgatag cttcagctga catgccgcga
     1561 acagggtctg gaccattaaa ggttgttgct gggatcttat gttctgcggc gactattagt
     1621 gctagataag ctccgagaga gtgacctgtg gttgttaagg cagaatgagg gtactttctt
     1681 ttgacttgtt gataaaactt ttgagcagat cgtaattggt tttcggcaat aacaaaattg
     1741 ccgccatcaa gattgccgct gactaaatca tcttgattgc cccgaatgag cagctgccaa
     1801 tccgtatcaa gatctctgga atccgcagca tttgtccctg cataggcaat cacaacctgg
     1861 gaggtatcga catcaccttg aacaataggg gctacagcca ttgcttgcat accgttgtca
     1921 ttgattttat gggcatcgtt gttattatcc tgaactaaga ggactcggta ttgcttaccc
     1981 gtcttatcat cgataagacg atttcccttt aaaacaatag gggcatcatt tgacttagct
     2041 ttactaggtt cgacattata gacctgttct gacaacttct tataactact atcggatatc
     2101 atcatattaa ctccttttct cacgagaata cgtaattgac actccctcta aagaaacttt
     2161 ttcaatgtct ttaattctat atttcacagg ccccatttct tccagactat ttttctcaac
     2221 taacttaaaa gtatctggat gataagagcg cccactaata tccgctaatc ctgacaaacc
     2281 atcaaacgaa aagcctattt cattttctcc atttataact actatcgttc cccacgaacc
     2341 tgtttcccga gaacgtcccc agcctgtaaa cttaacttct ttgacatctt catagtcatg
     2401 aaccagcagt ttagcaatac tagtttctaa atcctttttt tgttgttcct ctgttctttt
     2461 gccattcaaa ctaaaaacca taagcagccc tcctattaga atcattaaag caataaaagc
     2521 tttggtcgac tttttcatga aagttctcct ttcaatttct aataatagta tacaataaat
     2581 cagaagtcat agaataacca tattcaattt ttatgtcgta ttcgataaaa aatataccat
     2641 ctcaacaaac aatcgcttaa aaacgatttt agggtatatt tcttccctgc aagcaaagga
     2701 cacaaaaaag ccatctgaat tttcaacatc agacagctat ttcgtatgac tatggtataa
     2761 tggtttctgc agaaaagtta aggcggtggc tctaatttct gaaaggtggt ggtgcttatg
     2821 actgtaagtg ctaaaatcca aagagaaagg agcgaatatt gtccgtttac gaggcaatgc
     2881 aactcatgct tgggttcggt agttttctac tttcactcat tggcttagtt gttattatcg
     2941 taaaaatgag caataaaaaa taaccgtcta actttagcga gtaacggtta ttttttaact
     3001 aaaaacaagc taccgtctta aacggttctg cattgggtag ttgttttgag caactgtcct
     3061 ttttctattt tcattatatc tcagctaaga aaaatagtca aatgagatac tattttggca
     3121 gctaaattgg tagctaaatc ttcaaaatac ctatttttcg ctaaattcga ttaaaattaa
     3181 atcctatctg tctgctacgc tttaaactct cactctagta cttcatcacc atacgacaaa
     3241 aagagcctga gaaacttttt gtctcagact ctctcaaagc tcttagctta atatcaagca
     3301 aagtcatgca ttaagcgata tcaaaagcta gttttccacg tgatacacca atcttgaggc
     3361 tttgaccgct tgataactct cctgacagca ttaattctgc taacctgtcc tcaacctctg
     3421 tttgcaaggt gcgacgaagt gggcgagcgc ccatttcaac atcgtaacca gcttcagaca
     3481 agtacttgag agctgatggc tggaacttaa ggctaatatg cttttctgcc aaggctgcaa
     3541 tcagcggctt aaccataatt ttcaccacat cacgcatgtt ttcctgtgtt aggctatgga
     3601 agaccacctt ttcatcaatt ctgttgataa attcaggccg ataagccttt ttcaattcct
     3661 ctaaaatacg cttttccatt gcttgatggt catgaccgat cgctttagcg ccaaatccaa
     3721 ccgtcttatc atctcttaga gcagttgctc ctaggttgct cgtcatgata ataatcgtgt
     3781 ttgaaaaatc aaccttacat ccacgactat ctgttaacat accatcatca aggacctgca
     3841 gcaggatatt aaagatgtct gggtgagcct tttcaacctc atcaaaaaga agaacggcat
     3901 aaggcttatt tctaaccttt tcggttagct ctcctccctc atcatagcca acatagccag
     3961 gaggagcccc attaagacgg gaggctgcaa atttttccat gtactcagac atatcaaaac
     4021 gaataagggc tgactcatca tcaaagagta attcggccaa ggcctttgct agctctgttt
     4081 ttccgacacc agttggacca agaaacataa aggagccaat cggacgcctg cctgtgcgaa
     4141 tgcctgactg gttacgacga atggctcgtg caatagcaga aacagccatt tcctgaccaa
     4201 caacacgctt atgcaattcc ttttccagat tcaggtattt tttactatcc gcctgagtta
     4261 gtttttctag gggaatacct gatagcttgc ttaaggtgtg taacatatca tcttcagtaa
     4321 ctgctgttgg ttttagcttt ggttgcttat cctctttgac taaaagggct gacaccttgc
     4381 tcatatcacc atcaagcagg gcttgatcaa gcggtgttat aaagtcaggc tgcgtctttt
     4441 taaccatact ttgcaccatc gcactggctt catcaagcag atcaatcgct gagtctggaa
     4501 gctgcttact tgtcaaatag cgccgagcca gcttcacagc agtatggaca gctgtatcag
     4561 agattgttac attatggtac tgttcatagg aaggcttcaa gccaagcaaa atctgataag
     4621 cgtcctcaac actaggctcc tcaatcaata tcttggcaaa gcgacgagaa agggctgcgt
     4681 ccttttcaat gtgcttttga tattcctctt gagttgtagc gccaaccata tgcagggtac
     4741 cgcgagaaag ggctggcttt agaatattag cggcatcaag tgtgctgtca ataccacttc
     4801 ctgatcccat aatggtatgt agctcatcga caaacaaaat gatcttacca tctgcttcaa
     4861 tatcgtcaat gagttgattc atgcgctctt caaaatcccc acgaaaacgg gtacctgcaa
     4921 ccacactcat catgtcaagc tccaagacac gcatgtcttg taattcataa ggaatggctc
     4981 cattagcaat tcgctgcgct aagccataag ctagagcagt ttttccgaca cccgcatcac
     5041 caacaagaac aggattattt ttcgtcttac gacaaagcac ctgaaccata cgtgacacct
     5101 ctttttctcg tccgatgact ggctctaata agccctgtct tgccatctct gtcaggtctc
     5161 ttgtaaagtc tgatagctca ccagctgtac tctgtggctt catcatttca gaaaaggtgc
     5221 ctactgattt actcttttta ggcttacgca actcatgaat cgccttaata gtttccttgc
     5281 tatagccggc atttagctca atagccttac gtaaatccgc aaacctaggc tctcccttgc
     5341 cagaatcctt gagcctgtag cctgccaatt ctaacagacg actggccata atatccggat
     5401 tgagcaaaat agcaaagagt acatgctctg agccaacctc atgctcattg ataacctgac
     5461 agatagcatg agcaaatgct agtatttctg ataaggcctt ggattgtggc ttgaattgga
     5521 cagaagtcac ctctttggga ctttttccca tggctaaaat agcagcagcc tcatactctt
     5581 cagccctaat ctttcgttca aattcgctta acaccatggc cgctaaggaa tggtcaacag
     5641 ctaccatagc taataaaata tgccaggtct caaggtaagg actatcaaag cgctctgctt
     5701 gaaattgagc ctgattaaaa atgtcttgca tctttaatga ataaatcatc actaattgct
     5761 tccctttcta tcaattcgtt gcaataggcg ataaagcata cgagcacgaa tttctggtgc
     5821 ttgatgtccc aaaacatcat tagaagctac agctaagata atgtttcctt cgcgctctgt
     5881 taacagttgc tcatcaaaaa gcagctgaat cgaatctgta aaggcctgct cgcttaaaca
     5941 atcatcaata gaagcgatca acgtaccaat caggtggtgc ttatccgaaa aatgaacctt
     6001 agcaatacga atgtagccac caccaccacg cttactttct acctcatagc ctctgctttc
     6061 tgtaaaacgg gtcttgatca cataattaat ctggcttggt actacttgaa aggaatccgc
     6121 cagcatggag cgcttgatct ctgcgattcc tgattgggct aacaattctt tgatatattc
     6181 ttcgatacta tcggaagtat tttttgttgg catgccgtca ctcctttgct aaaacgattc
     6241 atttgctgct ttaagccttt atttgactaa aactgactaa cattatatca aatagcagtc
     6301 actaaaagca aatggaaatc actagaatgt aaaaggacag gtgctatcaa caacacccat
     6361 cccctattat ctgctcacta gattaagaca atttagtgat atttactgcc tgaggaccgc
     6421 gctgtccgtc ttcaacatca aacgtcaccc tttgtccctc gtctaacgat ctaaagccgt
     6481 cagactggat tgctgaaaaa tgtgcaaaaa catcttgacc attttcagtt gaaataaagc
     6541 caaagccctt ttcagcatta aaccacttga ctgtaccttg tgccatagtc atccacttcc
     6601 tttctataac gcatttgtaa acatagagag aaataaagat gccaaaacac aactactaat
     6661 tcaaaaacta atttactcgc tcagtgtaac acgaatggca gccactgtca acacataccc
     6721 ctcacaatga cagcttttct actccacctg ctaaaatgta aaaaagcaaa gtcatgctga
     6781 ccttgcttta acaatctaag gcggtagacg gatttgaacc gacgatcaag cttttgcaga
     6841 gccgtgcctt accacttggc tataccgcca taacaagaac tattttaccc tagttgatag
     6901 cattcgtcaa gataaaaata gcagctattt tttagcaggc tgctcctttt ttcggtttat
     6961 gttatttttt agagtttaaa tcagaaaatc atttttaata atattaaaat tatttcaaaa
     7021 acttattttc aagaatcttt gatattatca gagttttcta ttatttagaa tagttttaaa
     7081 cagtgtgact aaattcacat atgaaattgt tagaaaagaa catcaaaaac cttgataaat
     7141 ctagggttta caagtggaca gataagattt cttagcttat aatacaggta tcaaatgtaa
     7201 aaaaggagga catgacatgt ctttagtagg aaaggaaatt gctgaatttt cagcccaagc
     7261 ttttcacaat ggaaaattta tcactgtaac taatgaggat cttaaaggga aatgggcagt
     7321 tgtttgcttc tacccagcag acttttcttt tgtttgccca acagagctag gtgaccttca
     7381 agagcaatat gaaatactaa aatctttagg tgttgaggtt tattctgtat ctactgatac
     7441 acactttgtt cataaggcat ggcacgatga ttcagatgtt gtcggaacaa tcacttaccc
     7501 aatgattggt gacccatcac atgctatttc acaagccttt gatgttcttg gtgaggatgg
     7561 acttgctcaa cgcggtactt tcattattga tccagatggt gttatccaaa tgatggaaat
     7621 caatgctgat ggtatcggac gtgatgcaag cagcttgatt gataagattc gtgctgctca
     7681 gtacgttcgt aagcacccag gtgaagtatg cccagccaaa tggaaagaag gggctgaaac
     7741 actaacacct agccttgacc ttgtcggcaa aatttaagca ggcaaaggag aaaagctatg
     7801 gcattaagtc ctgatattaa agagcagctt gctcaatacc ttaatctttt ggaatctgac
     7861 ttagtcctac aagcttatct tggtagtgac gatagctcac aaaaggtcaa ggacttcatt
     7921 gaagaaattg ctgccatgtc agaccgtatc actgttgagg agactaccct aacacgtcaa
     7981 ccaagcttta agattaccca aaaaggtcaa gacagcggag tgatctttgc tggactgcct
     8041 ctaggtcacg agtttgcctc ctttatcctt gctctattac aggtttcagg acgtgcacca
     8101 aagattgagc aggatattat tgaccgcatc agggctattg accgtccttt aagctttgaa
     8161 acctatgtca gcttaacgtg tcataattgc ccagatgtgg tccaagcctt gaacattatg
     8221 gctgttctta ataagaacat ttcacatact atggttgagg gtggtatgtt ccaagaggaa
     8281 gtcaaggcaa agggcatcat gtctgtgcca actgtctttt tgaatggaga agaattcacc
     8341 tctggtcgcg ccactattga gcagctgctt gagcaaatcg caggacctct atctaaggag
     8401 gcctttgctg ataaaggagt ctatgacgtc cttgtcattg gtggaggacc tgcaggaaat
     8461 agtgctgcca tctatgctgc tcgtaaaggc ttaaatacag gtcttttggc tgagaccttt
     8521 ggtggtcaag tcatggaaac tgtaggtatc gaaaacatga taggaaccct gtatacagag
     8581 ggaccaaagc ttatggccca ggttgaggag catactaaat cctatgatgt tgacatcatc
     8641 aaagcccagc tggctacttc gattgagaaa aaagaccttg ttgaggttac tcttgctaat
     8701 ggcgctgtct tgaaggctaa aacagctatt ctagcgcttg gtgcaaaatg gcgcagtatc
     8761 aatgttcctg gcgaaaatga gtttaaaaat aaaggagtaa cctactgccc acactgtgac
     8821 ggtcctctct ttgaagataa aaacgttgct gttatcggtg gtggtaactc tggacttgag
     8881 gctgcacttg atttagctgg cttagctaag catgtctatg ttcttgagtt cttacctgag
     8941 cttaaggccg acaaggtgct acaggatcgc gctgctaaaa cagacaatat gactattcta
     9001 aaaaatgttg ctacaaagga tattgttggg gacgatcatg tcacagggct taactatatc
     9061 gagcgtgaca gcaatcaaga aaagcatctt gaccttgaag gagtctttgt acagattggc
     9121 ttggtgccaa atacagcttg gctcaaagac agcggtatca gcttaaccga tcgtggcgag
     9181 attattgttg ataaatatgg ttcaaccaat attccaggta tctttgccgc aggcgactgt
     9241 acagattcag cctacaaaca aattattatt tctatggggt caggtgctac tgctgctatt
     9301 ggagcatttg attacctgat tcgtcagtaa gttagcaaaa aaccaaggta actgtttacc
     9361 ctggtttttg ctttttagag gcctaataaa cagcaaggct gatagatcaa gcatttgggg
     9421 tacgccaaat gcttgaagaa acttatgttc tctgatatct tttcatgatt catgtgttct
     9481 ttttcagaaa gattgatagt aaaactaagc tgcgcttgaa aaatggatcg tgtcaaaacg
     9541 tcaacatatc aaaaatgcat tgaaaacatg catatggtta gaaaataatg gcatgcattt
     9601 tcctcatgcg tacgacgtgg gttttagtgt atttaggctt gctatgacta gctttttttg
     9661 gtatactgtt gtagttgtgc agacaacaaa tactcatctt agatcgattg tgattctgtt
     9721 gccatcaggt ggagttgcaa gccgacgtct aagagaggaa aaaaacattt ctataaagga
     9781 gaaactactc atggcagtaa tttcaatgaa acaacttctt gaggctggtg ttcactttgg
     9841 tcaccaaact cgtcgctgga accctaagat ggctaaatac atcttcacag agcgtaacgg
     9901 tatccacgtt atcgacttgc aacaaactgt aaaattagct gatcaagctt acgagtttgt
     9961 tcgtgatgca gcagctaatg acgctgttat cttgtttgtt ggtactaaaa agcaagctgc
    10021 tgaagcagtt gctgacgaag ctactcgtgc aggtcaatac ttcatcaacc accgctggtt
    10081 gggtggaact cttacaaact ggggaactat ccaaaagcgt atcgctcgtt tgaaagaaat
    10141 caaacgcatg gaagaagaag gaacctttga ggttcttcct aagaaagagg ttgcacttct
    10201 taacaagcaa cgcgcacgtc ttgaaaaatt cttaggtggt attgaggata tgcctcgtat
    10261 cccagatgtg atgtacgttg ttgacccaca caaagaacaa atcgctgtta aagaagctaa
    10321 gaagcttggt attccagttg tggcaatggt tgatacaaat gctgacccag atgacattga
    10381 tgtgatcatt ccagctaacg acgacgctat ccgcgctgtc aaattaatca ctgctaaatt
    10441 ggctgatgct gttatcgaag gccgtcaagg tgaagacgca gaggttgcat ttgaagctga
    10501 tactcaagca gagtcaatcg aagaaatcgt tgaggttgtt gaaggttcaa acgaagctta
    10561 agtcaggctt attgaactag gatagcttct tgctattcat aacatggtct aacggggcaa
    10621 agcattccgc tctatctcgt tattttttaa gtaagaaaac ccagcaggtc aaaggctctg
    10681 ctaaagcgag ctttaagagg accgattcta attttggagg aaataaaaat ggcagaaatt
    10741 acagctaagc ttgtaaaaga attgcgtgaa aaatctggtg ccggcgttat ggacgctaaa
    10801 aaagcacttg ttgaaacaga tggcgacatg gaaaaggcta ttgagcttct tcgtgaaaag
    10861 ggtatggcaa aggccgctaa aaaagctgac cgcgttgctg ctgaaggctt gacaggtgtt
    10921 tatgttaatg gtaacgttgc tgctgttgtt gaggtcaatg ctgaaactga cttcgttgcc
    10981 aaaaacgctc aattcgttga attggtaaac gcaactgcaa aggctatcgc agaaggtaag
    11041 ccagctaata acgacgaagc acttgctctt atcatgcctt ctggtgaaac acttgctgat
    11101 gcttatgtca atgcaacagc tacaatcggt gaaaaaatct cattccgtcg ctttgcccta
    11161 gttgaaaaaa ctgatgacca acactttggc gcttaccaac acaatggcgg ccgtattggc
    11221 gttatcactg ttgttgaagg cggagacgaa gcacttgcca agcaagtatc aatgcacgtc
    11281 gcagctatga agccaactgt tttatcatac actgagcttg acccacaatt tatcaaggac
    11341 gagttggcac aattgaacca cgctattgag cttgacaatg aatcacgtgc aatggttaac
    11401 aagccagcac ttccattctt gaaatatggt tcaaaggctc aattatcagc tgacgtgatt
    11461 gcgcaagctg aagaagacat caaggctgag cttgctgctg aaggtaagcc tgaaaagatc
    11521 tgggacaaaa ttatcccagg taagatggat cgcttcatgc ttgataacac taaggttgac
    11581 caagcctata ctcttcttgc tcaggtttac atcatggacg acagcaaaac ggttgaagca
    11641 taccttgact cagtcaatgc taaagcgatt agctttgctc gctttgaagt cggtgaaggt
    11701 attgagaaaa aagctaacga ctttgaatca gaggttgctg ctacaatggc agctgcgctt
    11761 aacaactagt ctaatcataa gtcataagat tgaggacagc ttttaagagc tatcttcaat
    11821 ctttttttac gcctaaaaaa agagcttttc gagcctatcc aacacaaaaa gactaagaga
    11881 agcatgcctt cctccacaag ctagactata cgttctaacg ataggagggc cgtacaaagc
    11941 ctcttagtct ttttttaatg agcaatgatt accaaataat cacacgatcc tctggagcac
    12001 gccacattgg atcaccttct ttaatgttaa attcttggtg gaattcatca aagtttgtca
    12061 aggtcacatt agtacgccat tgaccaggtg cgtggacgtc aatacttgcc atcatttgca
    12121 tgaattcctc acgcgccttc atacgccaga tggtggcaaa gttgataaag aaatctctgg
    12181 cagaaaaatc tggctctgac tgagctgcct ctaaggcaca ggcaacacca cctaggtcag
    12241 caacattttc agacactgtt aatttaccat tgactttagc accataggag tcaaggccat
    12301 caaattgctc tacaatttta tcggtacgct ccttgaaggc ggcataatcc tcgtctgtcc
    12361 accaattctt taggctacca tgctcatcaa aggaagcacc gttggtatca aaggcatgcg
    12421 aaatttcatg agcaataaca gcaccgatac caccataatt agctgatgag ctttgactca
    12481 acgaataaaa cggcgcctgc agaatagctg ctgggaacac aatttggttt tgctgtgggt
    12541 cataataagc attaaccatg ttggcaggca tgtgccattc actacgatcc acaggcttat
    12601 tccacttgct ccatgaatga gcaattgaaa ttttggctaa attctgagca ttttcaacaa
    12661 gtgatagctt atcatcgatg acctttttag cataggtttc tggtaatttt tccggatagc
    12721 caatgtgtgg ggtgataaca tttagctttg taatggcttt ctcacgtgtt gctggtgcaa
    12781 gccaatccgc agtttcaaga cgagatttat aaacctcaat catcttagct accttgtgtt
    12841 caacatcagc cttagcctct ggtgaaaatt tttcaccagc ataccaaagc ccaagagctt
    12901 gattaaatgg tccttgtgct aagtaatagg ctgctttttt cttgtccata gcctgtggag
    12961 ttcctgacaa ggcacgactg taaactcctg atagcacacg aatctcgtca gtcaaataag
    13021 catgataagc acctgctgct gtaagcacta gccaggcttt tagcagctcc caattcttct
    13081 cagaataata gtcagctgca aattctgtcc agaaccgctc ctctggcaca acaaccttgt
    13141 ctggtacttc acctaaaatc acagtaaata tattatctaa aggcaattct ggcactagct
    13201 tggtaaactc ggcccagtca taagggtggt aaagcttggc atactctgaa tattcctcac
    13261 gagaaaggac ataatctgcc agctgtttat caagcgtgat aaccttatcc agcaagtcct
    13321 taacctcttc atgtgaaaag ccaaatttag gcaatagctc ctcttgcatg ccacgccaga
    13381 tagcaagcag ctctttgcct ttgtcattgt ctttggcata gtaagtggta tctggcagga
    13441 taagacctgg tgcctctgcc caaaggacat ttaactgagc attcataaag tctggtgcta
    13501 cactaaatgg aaactgattt ggttttccat ttagctcata atcagccacc ttgctagcaa
    13561 actcggcaaa agatcctaag gccttgtatt cttcaattaa gtccaaggct ggcgctacgc
    13621 ccacctgatc acgcttgtca taatctgcaa ccaagcggtg aaacttgaca aagttttcta
    13681 atatagcgtc attgggaaca tgctcaccag ccaaccaagc atctgttgtg gtcagcatta
    13741 agtcctcaat ctcatctgct aggtctgaaa agccccctgt acgaggctta tcgtctggga
    13801 taacagctgt ttctgcccat tgaccattga cggcttgata aaaatcttct tgatatgttg
    13861 tcatgaattg ctcctttttt aaattaaacc attatgttag gactagcttt tactcctcat
    13921 aatgtaatct cttacatttt accaaaaaat cgttcaaaat actcgtttta tattaacttt
    13981 ctgttcaaaa ataagctcat tcttcgtatc gcatggcata gatagtaaac gcttagctgc
    14041 tttggtcctt ttatcagtaa gattaatcat aaaaactgaa caatcactaa gaaatcaaac
    14101 gattcttctc cagcttcatg aaaacagccc tcacaatatg ccaaaaactc agcagtaata
    14161 gcaaaaggcc ctatcagtcc tgacaaaaga attgcacccc aaaggtgaag ataaaaccta
    14221 aagcttaaga actttttcta tgacattaaa attagaaggt gaaatcaaga gttatcaatc
    14281 attatttcac gcctacagag tgaaagggac tgaaagcgca taactaaaag gactgaaccc
    14341 tgtttcatac aaagctcaat cctaatctat aaggtccagc tttttgggtg tggtacacct
    14401 gataggcttt tttagctaat ctgccgctaa aatcctcaaa acctgctgct caatagctgc
    14461 tggcgtcagc tggtattcct ctaatagata atccatctgt ccgacctgac cgaaacgttc
    14521 gtccaccccc atacggtaaa ctggagtatt actttcctga gccagtagct cacagatagc
    14581 actcccaagc ccaccgatac gattatgatt ttcaacggtt agaacaggac tgcctgtaag
    14641 tagacccttt agctcatcgg ccagtggctt taccctgaaa acatcaatca caccgataga
    14701 gtagccctgc tctgccattt tatcggctac ctctaagcac cttttgacca tgatccctga
    14761 gcaagccagc acaaggtctt ttccttgacg caataggcaa tagccattag aaaagtcctc
    14821 atgcccttga taaatagcct ctggcttttt acgaatggtt cgaatgtatt ttaggccatc
    14881 gagtgatagg gtttccttta aaacagcttt aaattgaacg tcatcactga cctcataaac
    14941 aatagccctt ggaatcaggc gcagcagtcc cagatcctca aagggcatat gggtgccgcc
    15001 attcatttcc gcactaactc cggcatcaga gccaataacc gttgcgccta gctgggcata
    15061 ggctaatgaa agaaacagct gatcaaacac acgacgtgag gcaaagggac caaaggtgtg
    15121 taggtaaggc ttatagcctt taatcgccag gcctgctgcc agaccgacca tttctgcttc
    15181 cataatgcct acattaatat agcgcttgcc aaacacctga tccaaatggt tggtggccat
    15241 tgagcttgat aaatctgcct ctaagacgac tacctcaggg tgctcttggt tggctgcaat
    15301 gaggaaatct cggtaaacat gacgcatttc ttgacttgct cgagtcatct tgtcacctcc
    15361 aaactagctc gtagctttct gacagcggca gcaagcatct ccttttcggc tgctgttggt
    15421 cttagatggt ggttagctgc cattgactct agctggctaa caccctgacc cttgacggta
    15481 tctaagacga tacacttggg cttatgactt gatgacgcct gcaaagccct gatggcttca
    15541 aaaatagcct gaacatccct accatctaca cgtaagcttt caaagccaaa tgccgtaaac
    15601 ttttcaacaa aatcacctgg acgacagatt gcctcggttg ttccatctaa ttgcttctta
    15661 ttgtcatcaa caaagacaat gaaatgactt agctgctggt gtgccgcaag ctggatagcc
    15721 tcccagcatt ggccctcgtt taattcccca tcaccaacga ttgcataggt ataatgtggt
    15781 gactgctcaa gcgcttgagc ataggcaatg cccgttgcta cgctaattcc ctgaccaaga
    15841 gagcctgtcg tcatgtcaat accaggcgtt aacagacgat ctgggtgcga gggcagactt
    15901 gttccattgg tattaagaga ctgtaaaaag gccttatcaa aaaacccctt taagtagaga
    15961 gtgctataga gggcaggacc cgcatgtccc tttgataaca ccagataatc tctatctgac
    16021 tggacaaaga gctctggtgt catgggcatg atttctccat aaagcacagc cagcaattct
    16081 acaatagaca agctaccgcc ataatgacca aagccaagat gattaagagt ctccaaggta
    16141 tttagacgaa tctctgctgc gaatcgcttc acatctgtta gaggctcatc actcaaaacc
    16201 atgcttattc ctccttagct actgattttc caacaacaga aagcccaaca agtccagcta
    16261 atatcacaaa aataccaatc acaatagctg tcacaccacc tatgctgtta agtgttccta
    16321 gtaaaatacc tgataagcca aaatcggcat ctgagaaggt tgagccctca aagcccaagc
    16381 cgcctaaaac aggcatcaag aaaatcggaa gatagctaat aagaacaccc tgtaaaaagg
    16441 ctcccacagt tgcaccgcgc acacctccag aagcattccc aataacacca gctgtggcac
    16501 cacagaagaa atgaggcaca acgccaggta aaatcactgt cgttccactt acgatcatca
    16561 cagccatgct cacaaggcca ccaacaaagc tagaaacaaa gccaatcagc actgcattgg
    16621 gggcataagg ataggcaatc gggcaatcca aggccggctt agaatgtggc actaattttt
    16681 cagaaatgcc cttgaaggct ggaacaattt cacccagaat caaacgaaca ccagctaaaa
    16741 tcacaaagac gcctgcagca aactgtcctg ccaactgcaa ggcaaagacc aagccatgtg
    16801 tgccagagga taattcctta ctaatccaag taggaccagc aaaaatagct acaatcaaat
    16861 aaatgattgc cattgataag gtaatgctta ctgtactatc acgcaaaaaa gcaaggctct
    16921 ttggaaaatc aatgtcctct gttgacttgg ttttgtctcc aacaagacct cctacaaaac
    16981 cgcttaacca ataaccaaga gagctaaaat gccccaaagc gaccttatcg ttaccagtca
    17041 gctggatcat ataccgttgc acaagagccg gtgaaacact catgataatc cctaaggcca
    17101 gcccaccaaa cacaatcaag gacactgacg tcaagcctgc aacagacata atcacagcaa
    17161 tcatacaggc catgtaaagt gtgtgatgcc ctgtcaagaa gatatactta aatcgggtaa
    17221 agcgagcaat caaaatatta aagatcattc ctgtaaacat aatcagagct gtcgctgacc
    17281 cataggtcgt caaagcaact gcaacaatag cctcattatt tggcacaaca ccagacagat
    17341 gaaaggcatg ctcaaacatc gttccaaaag ggttgagtga gccttgcacg atacctgcac
    17401 cacctgaaac cactaaaaac ccaacaaagg tcttaatgcc tcccttaaca atgtcaggag
    17461 caggcttttt ttgaagtaag agaccaacaa tagcaatcaa ggcaaccaaa atagctggtg
    17521 tgctaacaat atcaagtaaa aatgtcatct tatcctcctt ctaaacaagc cccttttcct
    17581 ggcaaatagc ctttaccaga ctagtcaatt cgtccatatc aatgatacta tttaaaatcc
    17641 tcacatctcc cagatgctct gccgagtctg ccaaatcacg cccaacaatc cacacatctg
    17701 ccgctgtggg atccgcgcca ccaagatcat aatgctccac ctcaacaccg gttactccca
    17761 agtcctttaa tacggattcg atattcatct gaaccataaa gctagaccct aagcctgaac
    17821 cacaggctgt accaattctt aatgccattt tatgcctcct ctgcaataat agttttaata
    17881 tcctcaaatg atttagacgc aagtaaagcc ttgacctgct cattgtctct taaaatggtc
    17941 gtcagccgag acagggcctt tagatgtgtt tcattatcaa tagcagcaat acaaattaac
    18001 aaacgaatct cctgcttagg atcatctaac aaataaatcg ggtgctctaa aacaagcatc
    18061 gacataccta cctgattcac accatcctct ggcctcgcat gtgggatagc aatcccctta
    18121 cctagattaa taaaagtacc aaactcctca accttagcaa tcatagcctc cgggtagctc
    18181 gcttgaatct gcccactctc taacaagggc tgagccgcca aataaatagc ctctctccac
    18241 cccaattgct ctgaggttga ttgataggtt ttcttggtaa ttaagtcttg taacactggt
    18301 cgaatatcct ttcttttcac accttgtctt aaatattgct gcaaagcaaa gcgcagcttt
    18361 tctttttgat gaatgaccgc atatgagctg ataagatgga gcagctcttc aacctctagc
    18421 cgatagccaa tatctggaaa atcacgatta accaagctga ccagctgaaa agcctgctca
    18481 tcagtcatta tcatagggac taaataaaag ggcttatcag tctctaatcg tatcgttgaa
    18541 aaaaccaaat catagccgct cttatctaat tgcccaagct gatcaagcct tgaaagcccc
    18601 cgaaaagcaa tatcaggaaa taaaagcttt aaatgctcct tgatcattaa agaagaacta
    18661 acaccattag gacagacaat cacagcctga taggcttgac gatgaaaatc tcttccctgc
    18721 tgctttaaat agcctccaaa atgaagaaca aaataagcaa tttcactatc tggtatagga
    18781 ctacccagct ccttggctaa aggctccaga gactgcttta ccaagtcaaa aagctcagaa
    18841 taactatcct taatccgcaa ggtataatca ttatcacttg gcaaaccata gcgcaaacgg
    18901 taataggctg gaatcaaatg ccttttcaaa ttctccttga gctgatctgc ctgactaaag
    18961 cttagtaaag caaccccctg catttgatca acaatcgcaa cggttagtga ttcaaagaaa
    19021 tcatcaccaa cagtaccctc accctcaaag cagcccgcta acagcaattg aaaataggcc
    19081 tcatcagctt caaatagctg atacttaaga gacaattgct gcattatttc tgccaccaaa
    19141 agggccgtta gctgatccag ctgctcagaa accactacct gtctttgctt gaccctatca
    19201 acccgtcttt ggtaacgaca taaaataaag atgacagcgt acaaacagac ctgcagacga
    19261 tcaaggatcg gagacatctg aaaggtctga taaaaatggc tcacacgttt ttcaagcgct
    19321 tcaaacgaca cctgatagtg ccaagaagcc aaaatatagt ccaaggccca caagccaata
    19381 ggagatttaa gcaaagtagc aatcattact aaagccaacc ggtgcttatt aatctcatca
    19441 ccaactaaga tatagccgct tgctctggta tactttaatt ccaagtcaac atctgccagc
    19501 ttctgccgca aggccttaat atctgtcaag gctgtgttct tgctgacctt taaaaagtcc
    19561 tgataatgac tatttgaaac aaaatccctg cggcaaaagg tatacagata gataagattg
    19621 atccgctctg cctgagaaag ataaacctgc tcagcattaa tcaacgtaaa caaatgatct
    19681 gactcagcct taagctgctg actgatccga tagccagacc ttgttgcatc tagctctgag
    19741 agctcatgct gagccaaaaa ctcattcagc tcatcaatac ggtccttaat ctctctaatg
    19801 gtgaattttg tcttaacact cagctcgtaa agtgataagt cttgataagt catcaacgtc
    19861 atcaaaatga caactgcttt gctatcaacc atttgatttc ctttctaaat tcattctatc
    19921 gaaaacggtt acaataaact agtccccatt gggcacaatt tcttatccaa catcatcaac
    19981 agcccttggg ctcaagatgc caatctaaac aggctaccag ctcctcctaa ctatcaataa
    20041 agagcaaaca agcccatctc tgccgctaag caattgtccc catgatttcc taagtccaag
    20101 ccaaagctaa agctctttgg agtaataacc gtcaaaaatg ttccaaataa tcaaaaaaac
    20161 tgattgacct catcagcatg tgataactct agatataagc ctaaaacaag attacagact
    20221 taatagttaa ctggtaatct tttattatac cacgaaaacg gttaccaaaa aagacttgtg
    20281 ttttattatt ttaataatat aatgaaacta taagatatct tattaaatga caaataacta
    20341 ccatcttggt tagaaaggag taaagctaat taacccttag tagatcacca tcgttttcag
    20401 aaaggaaatt caaaatgaaa aaagtaaaac aattgatcat cgcaatgata gcgtccttat
    20461 tactcattgc taacactgta ccttccattg tatatgctag tgaagtgact aaaattcaac
    20521 aggaagaaaa agtaattgaa gaaaaattat cacaacctct agaaatttca aaaagtgagt
    20581 tagatacatt aatccaagag aaaaaagctc tttatccaaa tttaacagaa caagaaatgc
    20641 gtgaaattgc gtataaagcc atgagtccat acacttttag agctagtgta tgggacgggc
    20701 aaggagtaac cttagatgaa ttcgcttggg cttttgatgt tattgtaggc gggttaatta
    20761 gtggatatgc aaccatcgga aagtacgttg ccaaacatgg agtagctgcc gctcgagctg
    20821 tacttagccg agctgcaaaa gctgcagctc aacgacttgg tgtactaacc ggatttattt
    20881 ccggtttact tagagctgca ttctcagtaa taaacattta ctataatgtc ggatatgccc
    20941 tagcacaata tgtcgatgct cgagattatc acccaaataa cggtcgtata aatgcgtggg
    21001 cttaagaact atatttgtta ttttattatt gtaatgtcag tttatacagc aatagcatat
    21061 tgtttcaatc gcttatcctt atcatttact ccaaaactag ttttctattc ggccataacc
    21121 acctatactt tttacataac aaaaaataaa gactga
//
LOCUS       DARYMD010000035        20405 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.035, whole genome shotgun sequence.
ACCESSION   DARYMD010000035 DARYMD010000000
VERSION     DARYMD010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20405
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(85..1350)
                     /locus_tag="TU818_001327"
     CDS             complement(85..1350)
                     /locus_tag="TU818_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL0924140.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     VLDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTISLTSVTALAESLVAQNNGIIAAIDQGRKERAQLEAAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIEQTERQP"
     gene            complement(1364..2221)
                     /locus_tag="TU818_001328"
     CDS             complement(1364..2221)
                     /locus_tag="TU818_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924141.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QASEANTTN"
     gene            2564..3856
                     /locus_tag="TU818_001329"
     CDS             2564..3856
                     /locus_tag="TU818_001329"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL0924142.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(3971..4744)
                     /locus_tag="TU818_001330"
     CDS             complement(3971..4744)
                     /locus_tag="TU818_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL0924143.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEVVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            4869..5615
                     /locus_tag="TU818_001331"
     CDS             4869..5615
                     /locus_tag="TU818_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL0924144.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            5630..6610
                     /locus_tag="TU818_001332"
     CDS             5630..6610
                     /locus_tag="TU818_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL0924145.1"
                     /translation="MKEGRKRLLAKVAYLHYVQGKSQTAISKQMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTVKDGDKIGLSWGATLSSLIDELDPKVMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQKDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGHQ
                     TSQWRDLLTDKDYKQLADDKAVGEVCCRFFDQEGHSVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQAKAKAILAALKAKFINYLITDKATIMAVLALDQDQTADTYLS"
     gene            6849..7169
                     /locus_tag="TU818_001333"
     CDS             6849..7169
                     /locus_tag="TU818_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL0924146.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINFIKEIIELRKE
                     LAEN"
     gene            7194..7502
                     /locus_tag="TU818_001334"
     CDS             7194..7502
                     /locus_tag="TU818_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0924147.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEVICKENGIPIAVIPMADYGMLDGDKVLDLALSLIKE
                     "
     gene            7513..8817
                     /locus_tag="TU818_001335"
     CDS             7513..8817
                     /locus_tag="TU818_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0924148.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKKGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPWAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTVIYFPFFKVQDNIAYQNELAAEKA"
     gene            9098..11515
                     /locus_tag="TU818_001336"
     CDS             9098..11515
                     /locus_tag="TU818_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL0924149.1"
                     /translation="MTEAKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPKEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERTRAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLINLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            11530..12198
                     /locus_tag="TU818_001337"
     CDS             11530..12198
                     /locus_tag="TU818_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL0924150.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLTAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNRAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWQAIHH
                     RQTI"
     gene            12323..13414
                     /locus_tag="TU818_001338"
     CDS             12323..13414
                     /locus_tag="TU818_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL0924151.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHGLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEIPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYAKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVASALVAVDAYVCSRT"
     gene            13921..14973
                     /locus_tag="TU818_001339"
     CDS             13921..14973
                     /locus_tag="TU818_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL0924152.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYFDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFIEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEKWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYKLLD
                     SSKCSDSAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            15002..15580
                     /locus_tag="TU818_001340"
     CDS             15002..15580
                     /locus_tag="TU818_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL0924153.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSPYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WDDFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            15779..16687
                     /locus_tag="TU818_001341"
     CDS             15779..16687
                     /locus_tag="TU818_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0924154.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPTG
                     PQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDPGAPGPKGE
                     KGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQKPKGDQ
                     GKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALPATGEI
                     NHPFFTLAALSVIASVGVLTLKGKKD"
     gene            complement(16923..18269)
                     /locus_tag="TU818_001342"
     CDS             complement(16923..18269)
                     /locus_tag="TU818_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0924155.1"
                     /translation="MKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTV
                     VQPRLGEDKDTADTANQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDI
                     IAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGQSS
                     HHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKG
                     QAVFDKLPLGRSLSIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVV
                     IVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYEIFVNGKKLS
                     QATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKV
                     AAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN"
     gene            complement(19309..19413)
                     /locus_tag="TU818_001343"
     CDS             complement(19309..19413)
                     /locus_tag="TU818_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0924156.1"
                     /translation="MTAFEVVQILLGFSSFTIALISLCYQIFKDDNKK"
     gene            complement(19793..20308)
                     /locus_tag="TU818_001344"
     CDS             complement(19793..20308)
                     /locus_tag="TU818_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEL0924157.1"
                     /translation="MKIVIIGYSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERMREADHIIYFNFNRFNCFYRAFKRYLK
                     YRGQTRPDMAENCNEKFDVEFMKWILLDGRSKNNLNNYKAVIKQYPHKTIVLKNQKQL
                     NHYMNSIQHDS"
BASE COUNT         5781 a         4094 c         4555 g         5975 t
ORIGIN      
        1 tgacagaagg gtatttttga ttgttaccaa tcaaaaagcc acaggctggg tagctgtggc
       61 aggtctgtta tatcaggagc tgctttaagg ctggcgttct gtctgctcga ttgtctcctg
      121 cttttctttg ccctcattga ggagagcttg aatgatgctt tggtcgcgca gcttgacaga
      181 atcattaatg gtttctgctg atttgataat ggctgcttcc agctgagctc gctccttgcg
      241 tccttgatca atggcagcaa tgatgccgtt gttctgggca actagacttt ctgctagtgc
      301 tgtcactgag gtcaacgaaa tcgttgggct ttgagctgtc cgctcaaggt ttggaatcgc
      361 ttccttgctt gtctcagcta gcatttgtag ggcagcgttg ttggcattga caatggcgtc
      421 tgcggtcatt ccagacttga cagactgctg catgatacct agctgagcaa tagataattt
      481 catggttgga atggtattgc gtcgcagcat gcctagcttt tgtcgcatgt cagaggacac
      541 cttgacgagg ttacgcattt gcggtgttgt tgcccaagcc acatagagtc gactaaggta
      601 ttcggtgtgc tgctgctcaa gggtattgag cacctctgtt gtcctagcca ataggtcaga
      661 ttgcacctga tactctggtg ttgtcgtgtc aagtactgca agctcctgct gcaaggtaag
      721 ggcgcggcta gaggtttcct tttgactagc ttcaagaaag gcaatcacac caaccagatt
      781 ttcaatcgac ttggtattgt cctcaatcaa gagctctgcg gctacaatat tacgagcaag
      841 cgtgtcttct tgcttgacaa cagctgcagc cataccgtcc attttttgct caatggtctg
      901 agaatcaaag taaaattcct gaagcgtgtt cttgctttgt ttgaatagct tttgcaaaag
      961 cgttggcttt ttttcaagct cagcagcggt cgcttcctta tatttggcaa taaaaccatt
     1021 aagctcacga ttggtgtttt tgaggagctc gtcaacctgt ggaatttgta atttcttttg
     1081 ctcagctaga atatgattaa cagtagcatt aactccttca acggctgctt gaccaaaatc
     1141 aagtaaggca ttttggtcct ccataaaggt atcaacaagt gctggtgcct ttgcagtgat
     1201 agcctgctgc tgctcaggac tcagcttttc gtagaaagaa atttgtccag tagtattggt
     1261 tggtagctta gtgataatat cggtggtttt atctgtttta gtgatagcat tattagcgat
     1321 ctggtcaata tcaaagtgaa attctgccat aatagctcct ttatcagttg gtagtgttag
     1381 cctcgctagc ttgagcagag cccttcatca tgcgcagact aacatcaaaa tcctttagct
     1441 cactttcgtt aagcttcctt agggtctcat caaggtccag gtcaaattgt tggatagcct
     1501 caagagcctg ctgcaagcgc tcatcagcat tgtaataatt tttaggtgtt tctttgattt
     1561 ttaggtagcc ctgcaaaatg tcttgaaacc tgcgcatatt agcctcatgg agtgctaaga
     1621 gttcctcgtg attatcagct cccttgattt tttctaaaat cgagtggtgg tcagcctgga
     1681 tattgtcata atagtgacgt agctcgggcg ccttataaat ggggtcagct gcctgctcct
     1741 ttaggctttc agccttcaga tttgctgcga tttgaatctt ttcgagctgt agctgcacat
     1801 cgctttccac gtcattagcc tttttggtca cacgacggta aatgctaata tccatgtgtt
     1861 ccttgaggtg accgctttct tttttgattt cactcaattg cggcagtagc tgcttggcta
     1921 aaatggcata ctgtgtaaaa tcttccttag ccagataatg atcaaggagc ttaacctttc
     1981 ggtcggcaag ctgaatagtt gcctttaaat cctccaagcg tttctcaagt gttgccgttt
     2041 ttaagcgagc ctgacggttc gaatagcgat aagcagcata accaacaccc agcgctgcaa
     2101 aaatcagaac agctttgtca atattttcta caactcctac taaaatcgcg aagcctatca
     2161 gccagccaaa ccagctaaag ccctttcttc gtcgagatac ttggtaatat tttcgtgaca
     2221 tgtaaaactt cctttgtact ttttatcaca gtaaacaatc aattagttct attttacctt
     2281 aaaaatgtga tttcttaaag gaaagattag cagatttagc attattttcc ttcaaagact
     2341 ggtcttgctt gctttttagt gaaatgtttg ctttctgcct gttttcagaa aaaagcattt
     2401 gccatttgat attttttctt aataatacca aggaaagata gcagaaaacc acattttttg
     2461 ctataatgag gtgtaacaga cacttgcagg tgagagtcct gccacattta tcaagaaagg
     2521 tgggggctct ctttctttgt tgagatgagc ctatatcgaa gatatgacat cagtagtagt
     2581 agttggtacc cagtggggtg acgaaggtaa gggtaagatc actgactttt tatcctcaga
     2641 tgcagaagtg attgcacgtt accaaggtgg tgacaatgca ggacatacca ttgttattga
     2701 taacaagaaa ttcaagctgc acctgattcc atcaggtatt ttcttcccag aaaagatttc
     2761 tgtgattgga aatggtgtgg ttgtcaatcc aaaatccttg gttaaggagc ttgcttacct
     2821 gcatgaggag ggcgtgacca cagacaattt gcgcatttct gatcgtgctc atgtcatttt
     2881 gccataccat atcaagcttg accagcttca agaggaagca aagggtgaca ataaaatcgg
     2941 taccaccatc aagggcatcg gtccagccta tatggataag gcagcacgtg ttggtatccg
     3001 tattgcagac ctgttagaca gggatatttt tgctgagcgc ttaaagacga atctggctga
     3061 gaaaaatcgt ctttttgaga aaatgtatga cagcgcaccg attgcatttg acgagatttt
     3121 tgaagaatac tatgcttatg gtcaagagat caaaaaatat gtgacagaca catctgttat
     3181 tttgaacgac gctcttgatg cgggcaagcg tgtccttttt gagggagctc aaggggttat
     3241 gcttgatatt gatcagggaa cctatccatt tgtcacctca tctaatccag ttgcaggcgg
     3301 tgtgaccatt ggttcaggag tcggaccaag taaaatcaac aaggttgttg gagtatgtaa
     3361 ggcctatact agtcgcgttg gtgatggacc attccctacc gagttatttg acgaggttgg
     3421 tgagcgcatt cgtgagattg gtcatgagta tggaacaacc actggtcgtc cacgtcgcgt
     3481 tggctggttt gattctgttg tgatgcgtca tagccgtcgt gtgtcaggca ttaccaatct
     3541 atcacttaac tctattgatg tgctatcagg ccttgagact gtaaaaatct gtgtcgctta
     3601 tgaccttgat ggtaagcgca ttgatcatta cccagcaagc cttgagcagc taaaacgctg
     3661 caaaccgatt tatgaagagc ttccaggctg gtcagaggat attaccggtg ttcgcagcct
     3721 tgaggatctc ccagaaaatg ctcgcaacta tgttcgtcgt attggcgaac tggttggtgt
     3781 tcgtatctca accttctcag taggtccagg acgtgagcaa accaatatcc ttgaatctgt
     3841 ttgggcaact atctaagctg tctattgtga tagcaccagc cttagctgaa tattaacgaa
     3901 aacacgagca atcctaagga aggttatccg gaggagctgc tcatgttttt taggtatagg
     3961 gcttttaaga ttaaaaatag caatggatat gatgattgag aaagatttgc tgataatcca
     4021 ccagatcctc tgggtgataa gcgacagcat cagccatgtc atagcttctg cctagcaatt
     4081 tgtatttgtt ttcaccaaac tggtgaaagg gaagtagctg cacctgatta atgtttagct
     4141 gattgaaaag ctcagaaaat gccttggcgt cctccaaaga atcgttgaaa ttcggaatga
     4201 cagggatacg caagacgact tccttgccca tctcaaaggc gtagtggata tttttaatga
     4261 tcaggtcatt tcgcaccccg gtgaccttgg tgtgctttag gcgattatag tgcttcaaat
     4321 cggtataaat aaagtctaca tagttgatca gctcagcaaa ttgctcgtgc ttagcaaagg
     4381 ctgtcgtttc gatagctgtg tgtagccctt ctgccttagc agcctttaga agcgctaagg
     4441 caaagtcaaa ttgagcaaag atttcaccgc cagacaaggt cataccaccg ccagattcct
     4501 cgtaaaaatc aagatccttt aaaacctcag caataatctc ttcaaccgtc ttttcctgac
     4561 caacgatttc tgtctttagt ccatctgtgc ttagcatttt ttcgggtaac gttttttgtg
     4621 attcgggatt ggcacaccag ggacagcgta agggacaccc cttgagaaat acagttgtgc
     4681 gaatgcctgg tccatcgtgt atgctaaaat gctggatatt aaatacaatg ccttttgtcg
     4741 tcatagcgag acttcctttc gttctaggac tatcataaca gataaacgta aataaatcaa
     4801 ttacgaacga aagttatttt tgcttttcat ttaccgccat aattgttaca atggaaagga
     4861 ggtaaattat gaatcgttta gaaaaaatta tccaattagt atttcaaaag aaaaaaatag
     4921 atgttaatac tttatctgag cagctacagg tctccaaggt aaccattcgt aaggatttag
     4981 acaagcttga aagtaagggg ctgctgcgtc gtgtgcatgg ctatgcggtg ctcaatagtg
     5041 gtgatgattt gaatgtgcgc ctgtcctata attataacat caaaaggcgg attgctgaaa
     5101 aggctgccga gctggtgcag gacaacgata ctatcatgat tgagtcagga tcgacctgtg
     5161 ccctgttggc agaggtgctc tgtcaaacca aacaaaacat caaaatcatc accaactcct
     5221 gctttattgc aagctacatt cgtcagtata gtagctgtca gcttatcctg ctggggggct
     5281 actatcagcc taattctgag gtgaccgtag gcccactttt aaaggaaatg atttcgcttt
     5341 ttcatgtgga tcgtgttttt gttgggacag atggctttga tccggcaatt ggctttatgg
     5401 ggaaggatat gatgcgctca gagggcgtcc gttacatggc agaggcttct gaggagctta
     5461 ttatcctgac agattctagc aagcttagca aacccagtct ggttcatcag ctatcgcttg
     5521 aggctgttga ccgtatgatc acagatgagc aattggaggc aagcacctat aagctcctgc
     5581 aagagcatgg tattgccatt gactttatat cgtagcgtag ggaactcaaa tgaaagaagg
     5641 acgtaaacgc ctgcttgcca aggttgccta cctgcattat gtgcagggca aaagccaaac
     5701 cgctatttca aagcaaatga atatttaccg aacaacggtc tgtcgcatgc ttgccaaggc
     5761 tagggctgaa ggcattgtgc gtatcgagat agctgattat gatgctaatt tgtttgcctt
     5821 ggaggagtat gttcgtcaaa aatatggctt agaaaagctt gatattgtat ccaatcaaat
     5881 ggaagatagc cctagtgata ccttggtaaa ggtggccaaa acagcagccg aggttttgcg
     5941 cagtacggtc aaggatggtg ataagattgg cttatcgtgg ggggcaacgc tgtcaagtct
     6001 gattgacgag ctggatccta aagtaatgaa ggatattatg gtgtgtccct tggctggtgg
     6061 tcctagtcat atcaatgcca agtttcatgt gaatactctg gtttatcgct tagcaaggat
     6121 ctttcatggc aatagctcct ttatcaatgc tatggtggtt cagaaggaca agcagctaac
     6181 cagagggatt ttgcagtcca agtattttga agaaaccctg acctattgga accatcttga
     6241 ccttgctctg gtcggtattg gaggagagcc aaatggtcat cagaccagtc agtggcgtga
     6301 tttgttgact gataaggact ataagcagct ggcagatgac aaagctgttg gtgaggtctg
     6361 ctgtcgcttt tttgatcagg aggggcatag tgttcatcag gaattgcaag acagaacgat
     6421 aggcatttca ctggaacagc tcgcgcgtgt gcctaagaca atagctgttg ctgttggtca
     6481 agctaaggcc aaggctattt tagcggcttt aaaggctaaa tttatcaatt acctcatcac
     6541 cgataaggct actatcatgg ctgtcttggc tttggatcag gatcagacag ctgacaccta
     6601 tctctcatag caatagctta atcagaagac gattgttttc tgattttttt gtgaccaaaa
     6661 atcttgcaaa gcatcacttt tgcacaatag tgctaaaaaa taaatacagc acacaatata
     6721 ttgacgaagg aagtaaaaat gataaaatga acttatcaaa gaaatgtaaa cgattacaaa
     6781 cgcaagctgt ttttttacga aaaaagcaag ggtaatcctt acatgagcac gtcacaaagg
     6841 agaaacaaat ggaattaatt gtaccagacc aaatcatcat ggggttaatc ctaaatgcag
     6901 gagatgcaaa gcagcatatc tatcaagccc taaagctggc taaggctaaa gactatgagg
     6961 ctagtgacaa ggagttagcc ttagctgatg atgctttatt agaggcgcat aatttgcaga
     7021 cacaattttt agctcaggag gctagcgggg caaaggcaga cattacagcc ttgtttgtcc
     7081 attctcagga tcacttgatg acaactatta cagaaatcaa ttttatcaaa gaaatcattg
     7141 agcttcgtaa ggaattagca gaaaactaaa gatcatatca aaaggaggac gttatgatta
     7201 aaattggctt attttgtgca gcaggctttt caacaggcat gcttgtgaac aacatgaagg
     7261 tggctgctga gaaaaagggc attgcttgtg agattgaagc ctactcacaa ggaaagctgg
     7321 cagactatgc accagctatt gatgttgccc tcttaggtcc acaggtggct tataccttgg
     7381 ataagtcaga ggttatctgt aaggaaaacg gcattccaat agctgttatc ccaatggctg
     7441 attatggtat gctagatggt gataaggtgc ttgacttagc gctcagcttg ataaaggaat
     7501 aggagcttgg tcatggctaa tatgaatgct caaaaaatca ttgcaccgat tatgcggttt
     7561 gttaatatgc gtggcattat cgctctaaag gacggtatgc tggcgatttt acccttgacg
     7621 gttgtcggaa gtctttttct tattgcaggt cagattccct ttcagggggt caatgacgct
     7681 atagcgagtg tccttggggc agactggaca gagccattta tgcaggttta tcagggtacc
     7741 tttgctatta tgggcttgat ttcctgcttt tcgattggct attcctacgc taaaaattcg
     7801 ggtgtggagc cactgccagc aggtgtgcta tcattgtcag ccttctttat cctgctaagg
     7861 tcctcttatg tgccaaaaaa gggtgaggct attggtgatg ccattagtaa ggcttggttt
     7921 ggtggtcaag ggattattgg tgccatcatt attggcttgg tggttggtgc gatttataca
     7981 gcctttattc gtcgtcatat cgtcatcaaa atgccagagc aggtgccgtg ggccattgcc
     8041 aagcaatttg aagcgatgat tccagccttt gcaatcttta tcctgtcaat gcttgtttat
     8101 atcattgcaa agctagtgac aggtggcggc acctttattg aaatgattta cgctgtgatt
     8161 caggtgcctc tacagggctt gactggctct ctttacggtg cgattggtat tgcctttttc
     8221 atctccttcc tatggtggtt tggtgtgcat gggcaatcag tggtcaatgg tatcgtgaca
     8281 gcgctgctct tgtcaaatct agatgctaac aaggccttgt tagcagcagg tgatttgtct
     8341 ttggctaagg gtgctcatat tgtgacgcag caatttttag attctttctt aattttatca
     8401 ggctcaggta ttacctttgg cttagtgatt gccatgattt ttgcagccaa atcaaagcag
     8461 tacaaggctc taggcaaggt agcagccttt ccggctctct ttaatgttaa tgaaccggta
     8521 gtctttggct ttccaattgt gatgaaccca gtgatgtttc tgccatttat tttggtgcca
     8581 gttgttgcgg ctctgattgt ttatggctct attgcgattg ggtttatgca gccatttgca
     8641 ggtgtaacac ttccttggtc tacaccggct attatctcag gctttatggt tggtggctgg
     8701 cagggggctc ttgttcaggc tttgattctt gtcttgtcaa ccgttattta cttcccattc
     8761 tttaaggttc aggataatat tgcttatcaa aatgaattgg cagctgaaaa agcttaacag
     8821 tatgctgata tcaatcacca tgacttaaaa acagtcttta gtcactagct atagcattcc
     8881 tagagaaggg cttagagaag gaggatttct tcacgtaacc atctcaatga ggtggttttt
     8941 ttgaaagaga ctcttagaca agtctatttt tgcacgatag tgcaacttta aatgaatagc
     9001 tgaatgctat ggatatgata ggcaaaatgt tttaaatatg gtaaaataat tacgaaagaa
     9061 agtaatttaa tttcgtaaga aacaaaggag gcctaatatg actgaagcaa agaatcccta
     9121 ttttggtaca ttaacagaaa gaatgcaccg ctatcgtgag gcagttctag ataaaaagcc
     9181 ttatattgat gctgagcgtg ctattttagc aacagaggct taccaaaaac accaaaacaa
     9241 gccatctaat ctaaaacgcg cttacatgct gcaaaatatt ttggaaaaca tgaccatcta
     9301 cattgaggac gaaagcttga ttgctggtaa tcaggcgtct tctaacaagg atgcacctat
     9361 ctttccagag tacactcttg aatttgtcct aaatgagctt gacctttttg aaaagcgtga
     9421 tggcgatgtg ttttacatca ctgaagaaac caagcagcag cttcgcgagc ttgcaccctt
     9481 ctgggaaaat aacaatttgc gggcccgctg tggtgtcttg ctgccgaaag aggttcaggt
     9541 ttatatggaa actggcttct ttggcatgga aggcaagatg aattcaggag atgcccattt
     9601 agctgtcaat taccaaaagc tattagaggt tggcttgaag ggctttgagg aacggactcg
     9661 tgctgccaag gctgcgcttg atttgactat tcctgaaagc attgataagt accattttta
     9721 tgattctgtt ctgattgtga ttgctgcggt taaggcttat gcagagcgct atgccaaatt
     9781 ggcgcgtgag ctggccaaaa cagctaatcc agagcgtcag gcagaattgc ttgaaatcgc
     9841 gcgtatctgt gacaaggtgc cttaccagcc ggcggaaacc tttgctgaag cggtccaatc
     9901 agtttggttt atccagtgta ttcttcagat tgagtcaaat gggcattctc tttcttatgg
     9961 ccgatttgat caatacatgt atccatatgc caaggctgat ttggaggctg gtcgtgaaac
    10021 agaggattct atcgttgagc gcttgattaa cctttggata aagactctga ccatcaataa
    10081 ggtacgcagt caggctcata ccttctcatc agcaggtagt ccgctgtatc aaaatgtcac
    10141 cattggtggg caaaccagag ataagcagga cgctgtaaat cctctatcct acctagtgct
    10201 tcgcagtgtg gctcaaacca aattaccaca accaaaccta accgttcgat atcacaaggg
    10261 cttggataat cgttttatga atgaatgcat tgaggttatg aagcttggct ttggtatgcc
    10321 agctatgaac aacgatgaaa tcatcattcc gtcctttatc aaaaagggtg tccttgaaga
    10381 agacgcctat gattattcag caattggctg cgttgagaca gccgttccag gtaaatgggg
    10441 ctatcgctgt actggtatga gctacattaa ctttccgaag attttgctta tcaccatgaa
    10501 tgatggtatt gacccagctt cgggtaagcg ctttgcaaca ggacatggtc acttcaagga
    10561 tatgacctct tatgacgagc taaaggcagc ttgggacgcg actctgcgtg aaatcactcg
    10621 catgagtgtc atcgtagaaa atgccattga ccttgggctt gaacgagagg tgccagacat
    10681 tctttgctct gcattgaccg atgattgtat cggccgaggc aagacgctca aagaaggtgg
    10741 agcagtctat gactacatct caggcttgca ggtggggatt gctaacctgt ctgattccct
    10801 agctgcactg aaaaaattgg tgtttgagga gggtcgccta accactgatg agctctggca
    10861 tgctctagaa acagactttg caggtgagcg tggtgaagag atccgtcaaa tgctgattaa
    10921 cgatgcacca aaatatggta atgatgatga ctatgctgat agcttagtgg ttgaagccta
    10981 tgatacctac attgatgaaa ttgctaaata ccctaatacg cgctacggac gtggtccgat
    11041 tggtggtatt cgctactcag gcacctcatc tatttcagct aatgtcggcc aaggtaaggg
    11101 aaccttagct accccagatg ggcgtcatgc aggaacaccg cttgctgagg gctgctcacc
    11161 agagcacagt atggataaaa aaggaccaac ttctgttttg aaatccgttg ccaaattgcc
    11221 aacagatgaa attgtaggtg gggtcttact caaccaaaag gttaatcctc agacactagc
    11281 aaaagaagaa gacaagatga agctgatggc tctgcttcgg accttcttta acaggctaca
    11341 tggctatcat attcaataca acgtcgtctc acgtgaaacg cttattgatg ctcaaaagaa
    11401 tcctgaaaag caccgcgact tgattgtgcg tgtggcaggc tattcagcct tctttaatgt
    11461 tttatcaaaa gccactcagg acgatatcat cgaacgtacc gaacacacac tataggagaa
    11521 caattactta tggaatacat gctagatact ctaaatctag aggctattaa aaagtggaat
    11581 cgcattttac cccttgcagg ggtaacctca aatccttcaa ttgctaaaaa agagggagat
    11641 attgattttt ttgaacgcat tagagaggtt cgtgcgatca ttggagataa ggcctctatt
    11701 catgtgcaag tcgtggcaca ggattatgaa ggtattttaa aggacgctgc ggctattcgt
    11761 cagcaatgtg gtgatagtat ttatgtaaag gttcctgtga caacagaggg actcacagcg
    11821 atcaaaaccc taaaggcaga gggctaccat atcacagcta cagccatcta tactaccttc
    11881 caaggcttac tggccatcga agcaggagca gattatctgg caccttacta caatcgcatg
    11941 gaaaacctca atattgatcc ggaggctgtg attggccagc tggcagaggc cattgatcgt
    12001 gaatgctctg atagtaaaat cttggcagcg agcttcaaaa atgtagctca ggtcaaccga
    12061 gcctttgctt tgggtgctca ggccatcact gctggtccag atgtctttga ggcaggcttt
    12121 gcgatgccat ctatccaaaa ggctgtagat gattttggca aggattggca agccattcat
    12181 catcgtcaaa ctatttaaaa gccatctaac ccatcgttat atgagcaaga gcagggacgc
    12241 ttctatcagc atagctagac tagtcttgct cactcttaga tggtgagaag cgtcaaaaat
    12301 ctgatttaga aagaggaaca tcatgaaagt atttgcaagt ccatcacgct atattcaagg
    12361 gaaaaatgcc ttatttacca atagtgacat catcaaaaag ctagggcaaa agccggtatt
    12421 gctctgtgat gatattgttt acggcattgt cggagaacgt tttgagggct atttaagtga
    12481 gcatggtcta ccacctgttc acgtagcctt taatggcgaa gcgtctgata atgagattaa
    12541 tcgtgtcgtt gccattgcta gagaaaatga taatgatgtc attatcggac ttggcggagg
    12601 caagaccatt gacagtgcca aggcaatcgc tgacatcttg gagataccag tgattatcgc
    12661 tccaaccatt gcctccactg atgctccaac atcagcccta tcagtgattt acacagatga
    12721 gggcgccttt gaaaaataca ttttctatgc taaaaatcct gagcttgtct tggttgatac
    12781 tcaggttatc tgtcaagcac caaagcgctt gctggcttca ggtattgctg atggtctagc
    12841 cacttgggta gaagcgcgtg cggttatgca aaaaaatggt gacacgatgg caggcggcaa
    12901 ccaaaccttg gcaggacttg ctattgctga ggcctgcgag cgtaccctgt ttgctgacgg
    12961 tctcaaggca atggctagct gtgagaaaaa ggtcgttact ccagctttag aaaatgtgat
    13021 tgaggctaat accttattaa gtggtcttgg ctttgaaagt gcaggacttg ctgctgctca
    13081 tgctattcac aatggcttta cagctttgac aggtgacatt catcacctca ctcatggtga
    13141 aaaggtggcc tatggcaccc taacacagct tttcctcgaa aataaatcaa gagaagaaat
    13201 tgaccgctac gttgactttt atcaggctat cggaatgccg acaaccctaa aagaaatgca
    13261 tttagacacc gccaccgaag aggatttctt aaaaataggg cgtcaagcaa ccatggcagg
    13321 agaaaccatt caccaaatgc catttaccat cacagcagag gacgttgcct cagcgcttgt
    13381 tgctgtagat gcttacgttt gcagcagaac ttaatgcaga actgctaaag ttctcttagc
    13441 cttatcagga gcctattgct ggtagctctt gaccaaagga ttgtacctac cttagcctta
    13501 attcaactgt tagaggtgtt cctcttgctg tggtaagaga ggttctttac tgctaaaggc
    13561 tcattctcag ggcaagctgg cccctccaaa tcatttaaaa agtcgtaaat ctaatcaata
    13621 atggctatca gtataggcta ctggtagtca ttattctata tctgatttat gagaacatac
    13681 cagtcagcag ctttgctgtg ccacctattt cttgtcatta cagtagctta gctttatagc
    13741 tgacagagca aatgcttcct catctattag ctcttaattc aaccgctaca gtaatagaaa
    13801 aagctaatca aagtaagggc tagttttttt tggtatcgct attaacagta tgtattagag
    13861 gctatcagcc tagccattat tgtggtataa tgacacaaca actttttaag gaggttagct
    13921 atgattcgga agattggtat tgtcagcttg tctagtggta tgcttggcga ggctaatgtc
    13981 aagcacgaat tggatttagg cttagcccgt ttaaaacagc taggcttaga ggtaacgata
    14041 ctcccaaatg ctttaaaggg catagactat tttgatcagc accctgaagc aagggcagca
    14101 gatatgattc aggcctttgc agatccgtct attgacatga ttttgtgtgc cattggtggg
    14161 gtggatacct atcgcctctt gccctatctg tttatcgaac atcagctaca agatgttgtc
    14221 aatcaaaagg tctttcttgg attttctgac accacgatca accacttgat gcttcataag
    14281 cttggtatta aaacctttta tggtcagtcc tttcttgccg atatttgtga gctggctgat
    14341 gacatgctgc cttactcgct ggcttatttt aaagagcttc ttgagacagg aactatcgct
    14401 gagatcagac ctagtgagaa gtggtatgag gagcggactg actttagtgc aaacagcctt
    14461 gggacacaga gaatagctca tcgcaatcaa ggctttgaac tattaaaagg tccgtcctta
    14521 ttcaagggag agatactagg tgggtgttta gagtcacttt ataaactatt ggattcgtca
    14581 aagtgttcag atagcgctaa gctctgtgag caataccagc tctttccaga tctgtctgac
    14641 tgggcaggca ggctcttgct tctagaaacc agtgaagaca agtcagatcc agctcaatac
    14701 cgccgaatgc ttgaaaccct caaagcaaca gggatttttt cggtgatctc tggattattg
    14761 gttggaaagc cgatagacaa cagctactat gacgactata agcagcagct gctagctgtt
    14821 gttgataatg atatccccat tctttacaat gtcaatgttg gccatgctac cccaagagcc
    14881 attgttccct ttggtgtcat ggctgtggtt gatgccaaag agcaggtcat tcgatttgtc
    14941 cctgatgagc atacagacca aaatgacgtc taacaaatca aaacagaaag tgagagagtc
    15001 tatgccaaag gttgacacga taacgcaggt ttattttatc cgccacgcag agcctaacta
    15061 tcaaaaccac aacgacgtga ctagagagct ctccgagcat ggggttaagg cgagccaaga
    15121 cctggttagg caactagcag aggtgtcgat tgacgccttt tattccagtc cctataaacg
    15181 ctctattgac accattgccc cactagcagc tagtagggca atggaaatta agctgattga
    15241 cgatttgaga gagcgtaagc tagctgatgc ttggatagaa gactttgtcg acacagccaa
    15301 aaagcagtgg gacgatttta cctttaaatt gccgacaggc gaaagcctgc aagaggtaca
    15361 agacagaaat atagcagctc ttaaccgtat tttaaaagaa gcaaaaggca agacagtagt
    15421 cattggcaca catggcacag cactgtcaac ccttatcaac tactatcaac cagactttgg
    15481 ttttgaggat ttcgaccgat ataagcatgt ctttccttgg atagtcagag ctagctttga
    15541 tggtgacaag ctgcttgggc ttaatgagtt tctagtctga caagtctagc cttgatccag
    15601 ctattatagg tgatgacagc aacaaaatca gataattaac cctttcatta aaaaaaaaaa
    15661 aaacaaaacc tcggagacaa actagccagc agctatttct catgagtaat caacatgtta
    15721 aaatcttctt tggagatatt agacaaccat aattattata tcatcaaagg agagaaagat
    15781 gacaaacaaa acaaagcgta caggattggt acgcaagtac ggtgcctgct cagcagctat
    15841 cgccttagca gctcttgcaa gcctgggagc aggtaaagca gtaaaggcag accagccagc
    15901 agcactaaaa tatccagaac ctagagacta ttttcttcat actcgtgaag gtgatgttat
    15961 ttatgatgag gatataaaaa gatattttga ggatttagaa gcctatttaa cagctagact
    16021 tggtgggatt gataaaaaag tagaagaagc tgcccaaaag ccaggtattc caggtcctac
    16081 tggccctcaa ggtcctaagg gagacaaagg agatccaggt gcccctggtg agcgcggtcc
    16141 agctggacca aagggcgata cgggcgaagc cggaccaaga ggtgagcaag gcccagccgg
    16201 acaagctgga gaacgtggac caaaaggaga tccaggtgct ccaggtccta aaggtgaaaa
    16261 gggtgatact ggtgcagttg gtcctaaagg tgaaaaaggt gataccggag caaccggacc
    16321 aaagggagac aagggcgaac gcggtgaaaa aggcgagcaa ggccaacgtg gcgaaaaagg
    16381 cgagcaaggc caacgcggtg aaaaaggcga gcaaaaacca aagggtgatc aaggaaaaga
    16441 tacaaaacca tcagctccaa aagcacctga aaaggctcct gcaccaaaag ctccaaaggc
    16501 ttcagagcag tcatctaatc ctaaagcacc agctcctaag tcagcaccaa gcaaatcagc
    16561 ggcaccaaca ggtcaaaaag cagccctacc agcaacaggg gaaatcaacc acccattctt
    16621 cacccttgca gctcttagtg tcatcgctag cgtaggcgtc ctaactctaa aaggaaaaaa
    16681 agactaagct agttattgta tctttcctgt atgacactag ctaacagcta atcacaaaca
    16741 ccagagagag gtcttttctg acctctcttt tatatacact gagcacatgc ttacctcaaa
    16801 aagacagtag tctaagtttg actactgtct caaaaatcat ttttatctaa agctttgatc
    16861 agcttgacaa atggtagaga aggacttgat ttctaaggcc tttgacctca gtttgacttt
    16921 tgttaatttt ccttacgttt tatagctgct acaccagctg tagccataac tgcaagtgca
    16981 gctgcggtga agaatgggtt cacagcctca cctgttgctg gcaattgatt agtcgttttc
    17041 ttcatctcag ctttagctgc tgctgcttta gaagctgtgt gagctggcgc tgctacttta
    17101 cctgcttgat cagctttttc aggactgagt ggtttagcct ctggcttagt ttctggtttg
    17161 gtttctggaa ctttaggtgc gtcttcttgt ggttttgaat gtggacttga ttttttaata
    17221 tctttagcat ctagggcaac gcttctttcc tcacctgttg tagcttgaga aagctttttg
    17281 ccgttgacaa aaatctcata gaaagtgcca tctagaagcc ctttagaaaa tacagctttg
    17341 ccatcagctc ctgttgttac tttctctatc acacgaccta ctctatgctt tagagtgact
    17401 tcttgtcctg ataaaggttc agcatcttca ttacgaacga taacaaccaa aggtgtttta
    17461 ctgtattctg gctcaactgt tccttttccg tcaacagtaa agctagctga atgcttgtcg
    17521 ccatcaacac ctgttcgtac agtatagcct tgaggaacgc cattcacaaa aattgataaa
    17581 cttcttccta aaggaagctt gtcaaaaaca gcttgtcctt tttcatctgt tgtcacagtc
    17641 gcaagtgttt ttctgccact tgttatatct accacttgga cgtcttttcc agataatact
    17701 ttaccctcag ggtctataac tgttgcggta aaagcaaagc taccttcaat aacatcatca
    17761 tgatggtggt gtgcatgatc actgtgatga ctactctgcc catcgtcaaa aggcttagaa
    17821 acatcaatct tatccaataa aataacatga tgatgatcgt catgtggata catcaaggcc
    17881 ttaccctctg aagtatccaa taattgaatc ttgtctaatg gcaagcctgt atttttggcg
    17941 atataagctt tttttacggc aataatatct tcagctgatt gattagtgtc tagcggtaat
    18001 ttatcagctg ctgctacagg atttgcggtt tctgatgctt ttgtaattgg tttatcagcc
    18061 atcacctcag tgctgtcaga taactgttga ttagctgtat ctgcagtatc tttatcctca
    18121 cctaacctcg gttggactac agtgtgatta tccactgctg gtgattcatc agcaaatgct
    18181 actgacgagt tagttgacat cgctaaacca gcagccatta aagcagctgg gataagtaaa
    18241 gagtatcggg taacttgatt ctttttcatt aataactcct tataactatt attcatttta
    18301 attaattaac cagttaacta tatcaatcta tcaaaaaaaa tatagtatgt caacctctta
    18361 aagtgattta atcagaacaa acgtatgaag aaaatcattt ggtgaaaaag aagcttattt
    18421 tagctgaaat agatccatta taaaagaggt gtcgtgaagt aactcaatat tcacctattt
    18481 ttgtcgcaag tattctaata ggaatagaaa aagggcagtt gcttgcaaca actacccaat
    18541 gtaaaaccgt taaagacggt gacagaaaat aactgttaac tgaactacct caaaagttaa
    18601 accaaagatc taaccgttgg atgttggttt gtagagcggt tattttttta ttgttatgtt
    18661 tacaacgact aagctcatca gtgtaaggga aagggacttc catattaaga agtatatata
    18721 catcctagat gagacgtgta atgaatgggt tgaacaaata gttgcttaat tttgggataa
    18781 gggttataat aaaaatagaa aaagggcagt tgcttgcaac aactacccaa tgcagaaccg
    18841 tttgagacgg tggctggttt tatagttaaa agataaccgt taactcgcca aagttaagga
    18901 cggttatttt ttattgtcat ctttgaagat ttgatagcac aagctgataa gcgcaatagt
    18961 aaagctacta aagcctaaaa ggatttatac cacttcaaaa gctgtcaatg ctttgactca
    19021 tcctttctgt tagattttga tgaactgccc ataggcctca cctacctttc agaaataaga
    19081 gccaccgtct taacctttct gctttatcat tatagcatat tgttattaag gttgactatt
    19141 cagactcgtc taaagaagtg taatagttgc ttaattttgg gataagggtt ataatgaaaa
    19201 tagaaaaagg tagttgctcg acacaactac ccatgcagaa ccgtttaaga cggtggcatg
    19261 ttttatgtta ttaaaaaata accgttaact cgccaaagtt aaagacggtt attttttatt
    19321 gtcatctttg aagatttgat agcacaagct gataagcgca atagtaaagc tactaaagcc
    19381 taaaaggatt tgtaccactt caaaagctgt caatgctttg gctcctcctt tctgttagat
    19441 tgtgatgaac tgcccatagg cctcacctac ctttcagaaa taagagccac cgtcttaact
    19501 tttctgcctt tttattatag cataccctat ctctgattga ctagcttaag aaggagggga
    19561 tgtgatttgg atacaaattt ttgttaactt ttttaaagtc tccaaatgat ttaaaaaaat
    19621 gatattaatg ctctaagtaa gaatattaat aatatggttt taccacttat tgtatgaggt
    19681 atcatttcta aagagttatt tttcagacag aaggcttgtt aaagcaaaca gaagcaatac
    19741 taaaggcatt agatgataat caaggccttt ttcatgtctt aaaatgagta tactagctgt
    19801 cgtgttggat agaattcata taatgattta actgcttttg attttttaaa acgattgttt
    19861 tatgaggata ttgtttaata actgctttat agttatttaa attatttttt gagcgtccgt
    19921 ctaacagaat ccatttcata aattcaacat caaatttttc attacagttt tcagccatat
    19981 caggacgtgt ttgtccccta tattttaaat atcgcttaaa agctcggtaa aaacaattaa
    20041 atctattaaa gttaaaatat ataatgtgat cagcctctct catacgctct tcataaagac
    20101 agcttgaata attaccttca ataatccaat gtttttgtga cataaatgtt gatatatcag
    20161 agaccatttg actaactgtt cgctcttgcc agtttgatgc aaaatgaatt ttgtctaaat
    20221 gaagtacagc acaattgtag tgttgaccta aaacatttgc taaagtcgac tttccagaac
    20281 cactatagcc aattattaca attttcaatc tttgtctcct ttgtcaatgc tgtactttga
    20341 cttatattat agcataaaga atatattttg gggacaaatc ctctttagac aagcaaaaaa
    20401 gcctt
//
LOCUS       DARYMD010000036        19343 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYMD010000036 DARYMD010000000
VERSION     DARYMD010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19343
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..1230
                     /locus_tag="TU818_001345"
     CDS             <1..1230
                     /locus_tag="TU818_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL0924158.1"
                     /translation="FNKHIYDKLYDYDTFTEVHYGGASSGKSHGVIQKVVLKACQDWK
                     HPRKVLFLRKVGATVYDSIFEDVKQCLELWGLLDKCKVNNSAYRIELPNGATFIFKGL
                     DNPEKIKSIKGVSDVVMEEASEFTLDDYTQLTLRLRDRKHLKKQIFLMFNPVSKVNWV
                     YKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELANRNEAYYKIYALGQFATLDKL
                     IFPKYEKKILNKDKLSHLPSFFGLDYGFINDPSAFLHVKIDDNNKKLYILEEYVRKNL
                     TNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRIIDVKKGPGSVMQGIQYLL
                     QYDWIVDERCVKTIEELENYTWKKDKKTNEYINDPVDSYNHCIDAIRYATSNHFLTLD
                     KKQSNSFNIFRKAGFGL"
     gene            1242..2744
                     /locus_tag="TU818_001346"
     CDS             1242..2744
                     /locus_tag="TU818_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0924159.1"
                     /translation="MLYTETFKDSTGNAKLLEFRFHRESRMRYQTSDLSGLFDEGYKL
                     LLDYIKHHESKQKPRIQELLDYAEGNNHTVCESGRRREADMADSRAIHNYGKYISTFK
                     QGYLVGNPIRVEYEDNDDAKKQLFKELADKNNFHQLNRRLVKDLSKVGRAYELIYRSM
                     DDKTEVVRLDPRETFIIYQADVGQASLVGVRYYNKSQLDRTKKTVEVYTDNEIIYFDY
                     DGQLTEVDRRPHIFKSVPITEYLNTDDGLGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPSYVDTKEKAIEYLRAMRKARLLNLEPPVDTEGREGSVDAKYLYKQY
                     DVNGTEAYKDRVVQDIHRFTNTPDMSDSKFAGTQSGEALKWKVFGLDQERVDLQALFE
                     QSLKRRYKLIARVSELLKEIDGFDISKLKITFTPNLPKSLHEKIEAFKALGGELSQKT
                     TMSITDIVENPDKEIASINDEAKNRSLLAQKMESEGRMTDRELARDYNHE"
     gene            2725..4302
                     /locus_tag="TU818_001347"
     CDS             2725..4302
                     /locus_tag="TU818_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL0924160.1"
                     /translation="MTTIMNKSKYWRDRVKKEMDAKEADDISLEQSMKQLHNYHFRNI
                     EKEIESFYQRYADKEKIDIAEARKRVSELDISAYQKKAKELVVKAEKLRKEGKTVTRD
                     DFTHQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKTFLDEGYRKEVEF
                     QAGLLGLSVASQASVKGLADAVINANFKGAKWSDSIWDRQDKLRSIISQSVQSAILKG
                     KNGLTIARDIRREFDVSVSYAKRIAITEHARVQMEVSRLSMAENGFAMFDIIPEPKAC
                     DVCKDIAKQGPYHMDKWRTGENTPPIHPYCRCAVVGVEEENSSNHESLDKLIKTEYNQ
                     SMKESSTYARNVLSAVSLIEPRITSQIKHIVKQSNGNLQGLDFRLKSLDSLARKISTD
                     SLLDDISPEEAANNINDALRYTAVFKPDNFFDDYHSMKNALVRDGFKIEKVKNTWLDD
                     GPYNGVNTVVSKDNVKFEIQYHTQESFDLKNGKLHELYEERRLPNITRKRKAELDKMM
                     FELSKSLTKPNQIERVN"
     gene            4304..4510
                     /locus_tag="TU818_001348"
     CDS             4304..4510
                     /locus_tag="TU818_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924161.1"
                     /translation="MITKYFFIKTEHPKIVRYSNGLTEVYNSAKGWEEQEAWYDRLFF
                     SDFSDFEEVTEKEAKMFIAGLTAA"
     gene            4507..4926
                     /locus_tag="TU818_001349"
     CDS             4507..4926
                     /locus_tag="TU818_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL0924162.1"
                     /translation="MSIVELAFRVAKKAHLGQVDKAGVDYIKHPITVASFVKTDEEKA
                     TAYLHDVIEDTSLTLLDLEEYDFPRSVIEAVDILTKKKGQDYQSYLNLVKTNKLARTV
                     KLADLKHNSDLSRLSEVTNKDLKRYKKYQEAIKYLNN"
     gene            5123..5392
                     /locus_tag="TU818_001350"
     CDS             5123..5392
                     /locus_tag="TU818_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924163.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENALQAEALINQNKEIMELKSIVE
                     RNALATNEELATVKDTVLDNQSVIKAIGDTVDYIKQNYKRKWGKK"
     gene            5428..5595
                     /locus_tag="TU818_001351"
     CDS             5428..5595
                     /locus_tag="TU818_001351"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924164.1"
                     /translation="MKVKEIAQVFNEYSDFFVVQNGKYLPGDRTSFFLDCELEIKEIS
                     IGIPDCLIIEV"
     gene            5777..6400
                     /locus_tag="TU818_001352"
     CDS             5777..6400
                     /locus_tag="TU818_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL0924165.1"
                     /translation="MNKKLLEKLFKCAPDTGTGSGGASDADSQQSETDGEPSSEDSFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIEEAVKAALDKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAENALEQVKTFEAA
                     FKKAVADEVKKTVRQLTPSTGAGAISTQTNYGANLASKIAQQSTTLF"
     gene            6411..6791
                     /locus_tag="TU818_001353"
     CDS             6411..6791
                     /locus_tag="TU818_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEL0924166.1"
                     /translation="MNKRKVTTSKEILHNLEYEAITVTLDSSTVGKKVIPAGTVLAGV
                     SDSVFKDRKQKVKTVANHEVSGESNICGILLTDVDLTDGDKAGACVYRGTVNADKLAD
                     SSIAENFTELATKLPHVVFIKGGK"
     gene            6794..7843
                     /locus_tag="TU818_001354"
     CDS             6794..7843
                     /locus_tag="TU818_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEL0924167.1"
                     /translation="MALIHEIITSENIKGFYNAKNENIDKTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEEMPYFKEAMLVKEADRQELNIISQ
                     TKNSDLIDTVLAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPSVKWSEAETATPLKDIEGAIEKMAERGFVPEAIIMNSKTFSLIKNAKSTLK
                     IIKPMAPDGAAVTKGDLTTYIADELGLKILFKDGMFIGDDGKSRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLMGGHATDADVSLVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIIDSIDQV"
     gene            7854..8120
                     /locus_tag="TU818_001355"
     CDS             7854..8120
                     /locus_tag="TU818_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924168.1"
                     /translation="MAEVIKTFRDKETTNTYYVGDDYNGDRIDELTAKGYLSGDKVSA
                     AAIEIDLDKLKVDEIRAKLDELGVAHDPKLKKPELLELLKQSAS"
     gene            8130..8483
                     /locus_tag="TU818_001356"
     CDS             8130..8483
                     /locus_tag="TU818_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL0924169.1"
                     /translation="MQKINTDSIIANVKLDLGIDDTLQDSLLNMLLKRVTDHFKAEYG
                     VDDIDNAFSFVLEDCLIARFNRRGSERAKSEEVEGHKTTYYDFLNEFEPYDKMIKSNL
                     NLIKDNSRKGGLYFL"
     gene            8480..8788
                     /locus_tag="TU818_001357"
     CDS             8480..8788
                     /locus_tag="TU818_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924170.1"
                     /translation="MRYADRITFVKATDEQYDPDLGEYTYTEVMIKTLPCFVMDLGMA
                     KSVQIFGDYQKTRKVVYLRQPYTDLLDHCLYKGKKYKVQVDKQFNTVFYLEGDDSICS
                     "
     gene            8769..9134
                     /locus_tag="TU818_001358"
     CDS             8769..9134
                     /locus_tag="TU818_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL0924171.1"
                     /translation="MILFVADISLKVVGTTGLKNKLELIAKKEAVKKIVRDNGKQLHR
                     KMVQKAVFTKGHSTGATRISITMQIGDDGFSVTVKPGTHYAGYLEKGTRFMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            9131..9520
                     /locus_tag="TU818_001359"
     CDS             9131..9520
                     /locus_tag="TU818_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL0924172.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVDLVLSVWGLQKKRKQVSDMASAIFSQAMSVASSDSFYWSLNIRQ
                     SSIQVLDDTTTVTPLKRAIVTLRFNLR"
     gene            9530..10121
                     /locus_tag="TU818_001360"
                     /pseudo
     CDS             9530..10121
                     /locus_tag="TU818_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
     gene            10183..10542
                     /locus_tag="TU818_001361"
     CDS             10183..10542
                     /locus_tag="TU818_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEL0924173.1"
                     /translation="MQLEIKGKTHNIKFGTRFVAEMDKNHIAEREGMKFGAGLQSTVP
                     FLFERNVVTLAEIIYTGTITESPRPSLNDIYDYIDEAEDIEKLFDDVLDELRQSNASK
                     LFITKLDKNIAEMATEA"
     gene            10584..10913
                     /locus_tag="TU818_001362"
     CDS             10584..10913
                     /locus_tag="TU818_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924174.1"
                     /translation="MIVLNCVRYLGMTDINEIGRLTLYEYDLLMIGKALASVDEAYKA
                     HKQAWINHQVSATRLVGGGKNKREVPVYKTFKEFFDYETEIKKITNEIDESYDKKAMD
                     LLLKANL"
     gene            10930..14184
                     /locus_tag="TU818_001363"
     CDS             10930..14184
                     /locus_tag="TU818_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL0924175.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLKSAVQSIEGLEKRSKGFSAVSQ
                     KAGSMFKSMLGANLAGQAITALGRTVSSGLISMIGEMNSSAKAWKTFDANLADIGFGK
                     QQILEAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKAMGKNLNELVADIQAGRVK
                     TKDFLEAVKQAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKINFSKFAAGLGKFLEGVNIDSIISRISTSISSIVSKIKGFWDGFNQTGAI
                     SAFSGALQSVWGALKNTAKAMSGGSWKTFGSIIGEIVKHVSNFARVIGDVVGKMDPSR
                     LKSWIATLAAVGGGLKIFEKLTGQSVIGSFLDKIGSKFKIFGNKAKEGTEQAFNGVKR
                     SGGIISKIFNGLGNIVKSAGTAIATAAKGIATGFSIAFKGLGSAISMVPPATWLALGA
                     AILAVGAAFALAGTQADGISQIFKTVGDVVVQVLQQVTNSLATLIPIIVSAIGSILPI
                     VAGAISQVVAAVAGGLSQIITAVANGVSTIIGAFTGLLGGVSSVITSISGVIQSLAGV
                     ITSVFNGIATIISSVGSAIKDVLTGLGSAFKGFGNGVKSALEGVGTVIKSFGSAVRNV
                     LDGVAHIFDSMGNAALNAGRGVKEMAKGIKMLVDLSLADLVATLGAVATGLGNMAGSA
                     GQMTTLSSAMSEVANGMARLGTSATIAITGLTVFATTITTIQTAIATLPTILTAAASG
                     FREIGDSATAAVGRIQTFAAGTTVVASAFASMQSMIRSAMAAIVSSIITSFNQAASQI
                     QSILSRVLSQARTFGSQLEQQMRQSGQRSGQNLAQGLSSQQGAVINAVSSMVNAAVSR
                     ANAGASPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARAKAMIHSPSRLF
                     AKRVGQYIPQGVAMGIYKNADVVDDSVGELFDSINSFDFNIADRLTSIGARFQGVVKS
                     ESSQSLSQQQEFVHTAQPAYVNFSLGGNEYEAFVSDITNRQAKIEKIRLKRSSW"
     gene            14216..14995
                     /locus_tag="TU818_001364"
     CDS             14216..14995
                     /locus_tag="TU818_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL0924176.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDMVDLEHQTTSVLGRDGEYFHNATVEVRKLEIKAKITGKDNRSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDIPEEVSNEQIIGLVFICYDPFKMSDIKTKKGNT
                     VQNDGLFNTKPIITLNLSSSTKEIRLLHVESQKYIRLTGTYTTDEIKIDMTTGKITQN
                     GRNILSDLDMVNSRYFDLLPGKNTLQCDNATITADFREVYL"
     gene            14992..17049
                     /locus_tag="TU818_001365"
     CDS             14992..17049
                     /locus_tag="TU818_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0924177.1"
                     /translation="MIYLFDKLEQLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPSQKEDVFKLFKVIDYNLEDSKYYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGISEIRTLSYYYISPRAAMIKMIEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     YDEPEAKEVEGHLPEAEKRQGYGRRIEFSDVVWSVEKGDSIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKAELLKATWDQLQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNREARSRKEAVQNMI
                     NDSIENITGLGMNLQEFFQGIEEKIATGKKEMEDNWRKVNLEFDNFKKLIEQEGRNFR
                     ERLEAETKELDERNQKELDEFRETLKNLSLPEEAIKKITEAIKVDDIPSLKQSFDELK
                     NEVSKNSEKSRLNAEIIGTNGKTRYNKNLLVGEPNRTKTYDQDFVEIEANDGGFRRGE
                     TYTISFSQTCELLKKVAITLTQPHNKGLKLVLTPTKAKMEAQTFDLTKDIEVISVYPL
                     SYRAVLTGDWYKSKQMDFNAAEVQDLALEMSYRDVVDSNNASLILDWSSNPDVIFDGN
                     GGS"
     gene            17049..17756
                     /locus_tag="TU818_001366"
     CDS             17049..17756
                     /locus_tag="TU818_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0924178.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGAQGPQGPAGETGPQGPPGPTGQRGETGPQGPPGPQGPPGADG
                     KMTFEQLTPEQKQQLKGAGIQSISLDYEGYLTIQLDNGQSFRSDISLKGPQGEPGING
                     MDGPRGATGPQGPAGDPASIPDDVVRRGELAAYLLKSEYKAKGAGSGLSYKVVTQSEY
                     DDLYDYSDNELILVTEG"
     gene            17758..18372
                     /locus_tag="TU818_001367"
     CDS             17758..18372
                     /locus_tag="TU818_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924179.1"
                     /translation="MAYKLYTKADVGDNMLLVVGHLPDNTKRLKIQRETLDVLSITHY
                     SSYDMVQLKSTVKRSHSKNTVVTLVAAAASKPKAKPKHVLNFAKANKVYLGSTRVIAV
                     YLGDRLLWSDKDSSGNKTVSVVGSLDIRQSQKMLYLYLIASDIADVKSKRIKSIAING
                     VNLSSAAQINFEDSDYYCLVTIERVANIKEIKNIAQKNKITLEF"
     gene            18383..>19343
                     /locus_tag="TU818_001368"
     CDS             18383..>19343
                     /locus_tag="TU818_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL0924180.1"
                     /translation="MSRDPTIVIDETNLVIGTDGRMHYTFTASQDNQKVRLKSNCLGT
                     AHFNQLMIERGDQATDYVAPVVVEGTGQATGVFKSLEEMLSGLKSIKLELTDTKNSNL
                     WSKIKLTTNGLLREYHHDHISTEIVETAAGIAKRIVDDTGQKLALINETIKGVKREYQ
                     DADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQKYDDELRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIKDRAGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTQTVKGLQSTVSDPKGKIQS"
BASE COUNT         6551 a         3379 c         4333 g         5080 t
ORIGIN      
        1 tttaataagc atatttatga taaattatat gactatgaca cttttacaga ggtccattac
       61 ggcggagcat cgtctggtaa atctcatgga gttattcaaa aagtagtatt aaaagcatgc
      121 caagactgga agcaccctag aaaggtgctt tttttacgca aagttggtgc aactgtttat
      181 gactcaatat tcgaagatgt gaaacagtgt cttgagttat ggggtctact agacaagtgt
      241 aaggttaata attcagcata taggattgag ctgccaaatg gggcgacatt tatttttaaa
      301 ggcctagaca accctgagaa aatcaagtca attaaaggcg tgtcagatgt cgttatggaa
      361 gaggctagcg agtttacgct tgatgattat actcagctaa ctcttcgtct gcgtgatcgt
      421 aaacatttaa agaaacaaat ttttttaatg tttaacccgg tatcaaaagt aaactgggtt
      481 tataaagcct tcttcgttaa gacacctaag aatacagttg tctatcaaac aacttataaa
      541 gacaaccgtt tcttagatga tgtcacgaga gaaaatatcg aggaactagc caataggaat
      601 gaagcttatt acaaaatata tgcccttggc cagtttgcga cattagataa gcttatcttc
      661 ccaaaatacg aaaagaaaat attaaataaa gacaaattat cacacttgcc ttcttttttt
      721 ggcttggact atggatttat taatgatcca tcggcatttt tgcatgtcaa aattgatgat
      781 aacaataaaa aactttacat cttagaggag tatgtgagaa aaaatctaac aaatgataag
      841 atagcaaatg ctataaagga cctcggatat gccaaagaag agattagggg agactcagca
      901 gaaaagaaat caaatcaaga gcttagaaat ttaggtatcc caaggataat cgatgttaag
      961 aaaggtccgg ggtctgtcat gcaagggatt cagtatctgc tgcaatatga ctggatagtt
     1021 gatgaaagat gtgtcaagac cattgaagag ttagaaaatt atacctggaa aaaagataaa
     1081 aaaacaaatg agtatattaa cgacccagtc gatagttata accactgcat tgacgcgatt
     1141 aggtatgcga catctaatca tttcttgaca ctggacaaaa aacaatccaa tagctttaat
     1201 attttccgca aagcaggttt cggactctag aaaggagaac aatgttatac acagaaacgt
     1261 ttaaagacag cacaggtaat gctaaattac ttgagtttag attccatcgt gagtctcgta
     1321 tgaggtatca gacaagcgat ttaagcggcc tttttgacga agggtataaa ctattgcttg
     1381 actatatcaa acaccacgaa agcaagcaaa aaccacgcat acaggagctt ttagactatg
     1441 ctgagggtaa taatcataca gtctgcgaat caggccgcag acgagaggct gatatggcag
     1501 acagtcgtgc tatacacaac tacggtaagt atatctcgac ctttaagcag ggctatttag
     1561 ttggaaatcc tatccgcgtg gaatatgagg acaatgatga tgctaaaaaa caattgttca
     1621 aggagctggc ggataaaaat aacttccacc aacttaaccg tagacttgtc aaggatttat
     1681 ccaaggtagg ccgcgcctat gaacttatct atcgcagcat ggacgataag acagaggttg
     1741 tgcgattaga tccacgagaa acctttatta tctatcaagc tgatgttggg caagctagcc
     1801 ttgtgggtgt gaggtactat aacaagagtc agctggatag aacaaagaaa acagttgagg
     1861 tctacacaga taacgagatc atttactttg attatgatgg gcaactgaca gaggttgata
     1921 ggcggccaca catttttaaa tctgtaccta tcacagagta tctcaatacg gacgatggcc
     1981 ttggtgatta tgagacggag ttgtctttaa ttgacttgta tgatgcagct caatcagaca
     2041 cagcaaacta tatgcaagat ttgtcagatg caatcttggc tattattggt cgagtatcgt
     2101 tcccgagtta tgtagacacc aaggaaaaag ccattgaata tctgcgtgct atgcgcaaag
     2161 ctaggttgct aaatttagag ccaccagtgg ataccgaagg tagagaaggt tctgtagatg
     2221 ctaagtatct ctataagcaa tatgatgtca acggcacaga agcttataaa gatagggttg
     2281 tgcaagatat ccacagattt accaacacac cagatatgtc agatagcaaa tttgcaggca
     2341 cgcaatctgg agaggcactc aagtggaaag tctttgggct tgaccaagag cgtgtagact
     2401 tgcaagcact gtttgagcaa tctctaaaac gtagatataa gcttatcgca agagttagtg
     2461 agctgttaaa agaaattgac ggatttgaca ttagcaaact taaaattact tttaccccta
     2521 acttaccaaa atcgctacat gaaaaaattg aagcttttaa agcacttgga ggggagttgt
     2581 cgcaaaaaac aacaatgtct attacagata ttgtggaaaa tcctgataaa gagattgctt
     2641 ccatcaacga tgaggctaaa aatcgtagtt tattggcgca aaagatggag tcagaaggta
     2701 gaatgacgga tagggagtta gctcgtgact acaatcatga ataagagtaa atattggcgt
     2761 gatcgtgtta aaaaagaaat ggacgcaaaa gaggcagatg atatctccct tgaacagtcc
     2821 atgaaacaat tacacaatta tcattttaga aatatcgaaa aagaaattga gtcattttat
     2881 caacgttacg ctgataaaga gaaaatagac atcgcagaag cccgtaagag agtttctgag
     2941 cttgacattt ctgcttacca gaagaaagct aaggaacttg ttgtaaaggc tgagaagcta
     3001 cgaaaagagg gtaagacagt aacgagagat gactttaccc accaagaaaa tgcagacatg
     3061 gccatctaca atttagcgat gaaaactaac gctttagaat tgttgcgctt gaatatcgac
     3121 ttggagatgc aggagctcgc aaatggcgaa cataagctaa ccaagacatt tcttgacgaa
     3181 ggataccgca aagaggttga gttccaagcg ggattgttag gactgtcggt tgctagccaa
     3241 gcaagcgtga aagggttggc tgacgcagtt attaacgcta atttcaaagg cgcaaaatgg
     3301 tcggatagca tttgggacag acaagataaa ttacgcagca ttatatccca gagcgtacag
     3361 agtgctatct taaaaggtaa aaatggttta actattgcaa gggatattag acgagagttt
     3421 gatgtgtcag tgtcttatgc aaagcgaata gcaatcactg agcatgcaag ggtgcagatg
     3481 gaagttagta gattatccat ggcggagaat ggctttgcta tgtttgacat tatcccagag
     3541 cctaaagcat gtgatgtttg taaagacatt gctaaacaag gtccatatca catggataag
     3601 tggcgaacag gggaaaacac gccgcccatc catccttatt gcaggtgtgc agttgttgga
     3661 gtggaagaag aaaatagtag taatcatgaa tcacttgata agcttattaa aacagagtat
     3721 aatcaaagta tgaaagagtc atcgacttat gctcgtaacg ttttgtcggc agtgtcattg
     3781 atagagcctc gaattacatc gcaaattaag catattgtca agcaatccaa cggtaattta
     3841 caaggacttg attttagatt aaaaagtcta gattctttgg ccagaaagat ctctactgat
     3901 agcttgttgg acgatatttc accggaagaa gccgcaaaca acataaatga tgcattacgc
     3961 tatacagctg tatttaaacc ggataatttt tttgatgatt atcatagcat gaaaaatgca
     4021 ttggtcagag atggttttaa aatcgaaaag gtgaaaaata cttggctaga tgatggtcca
     4081 tataacggtg ttaatactgt tgtatcaaaa gacaatgtca agtttgaaat tcaatatcat
     4141 acccaagaaa gctttgattt aaaaaacggg aaactgcatg aattatatga ggagagaaga
     4201 cttcctaata taacacgaaa acggaaggct gaactagaca aaatgatgtt tgagcttagt
     4261 aaatctttaa ctaaacctaa ccaaatagaa agggtgaatt gatatgatta caaaatattt
     4321 ttttataaaa accgaacacc ccaaaattgt tagatattct aatgggttaa cagaagttta
     4381 taacagcgca aaaggctggg aagaacaaga agcttggtac gatcgtctat tctttagcga
     4441 tttcagtgat tttgaagagg ttacagaaaa agaagctaaa atgtttattg cgggattgac
     4501 agcggcatga gtattgtgga gctagctttc agagtggcta aaaaagccca ccttggacag
     4561 gttgataagg ccggtgtcga ctatattaag caccctataa ctgttgcaag ttttgtaaaa
     4621 actgatgaag aaaaggcaac ggcttatctt catgatgtta tcgaagatac aagtttgact
     4681 ttacttgact tggaagagta tgattttcct cgaagtgtta tagaggcagt tgatatactg
     4741 acaaagaaaa aaggacagga ttatcaatcc tatctaaacc ttgttaaaac aaataaactt
     4801 gcaagaactg taaaattagc tgatttaaaa cacaattctg atttatctcg tctctctgaa
     4861 gtaactaaca aagatttaaa acgctataaa aaatatcaag aagctatcaa atatttaaac
     4921 aattaaacaa caacagacgg gcaaccgtct ttttttgtac cccaaaaaca ggaggaaatg
     4981 atgttgaaaa tagtgaaatt tttgaaatat gtttggattt ataagtgtaa acctgtcagt
     5041 ccaagtcttt atgcatcgag tcggattgag tacttcaaac ctcttggtta ttactgggaa
     5101 aaagcaacga taggagaaag caatgaataa acgaatcaaa aagaaacgta aactagaaac
     5161 agtagtagtg atgctggttg cggaaaatgc cttgcaggct gaagcgctca taaatcaaaa
     5221 caaagaaatc atggagctaa aatcaatcgt tgagcgaaac gctctggcaa caaacgaaga
     5281 gttagcgact gttaaagaca ccgttttaga caaccaatca gttatcaagg caattggtga
     5341 cacggttgac tacatcaagc aaaattacaa acgtaagtgg gggaagaaat gaagtatctc
     5401 aagaaaaagt aatagtaagg agttattttg aaagtcaaag agatagcaca ggtgtttaat
     5461 gaatattcgg atttttttgt ggtacaaaac ggtaaatatc tacctggtga cagaactagt
     5521 ttttttctag attgcgaatt ggaaatcaaa gaaatatcta tcggaattcc tgattgctta
     5581 attattgaag tataaaaaat tcaaagtcgt agcaatacgg ctttttattg tgccctgagc
     5641 atggcctaaa aaggctcaaa ttaatcacta gcgtggcttg tggataaata cacctaatag
     5701 agactagaaa acatgaggcg cccgttttcg tggctctgca gtgtgtttaa aagcaagact
     5761 agcgtgggag gaaaaaatga ataaaaaact attagaaaaa ctttttaaat gtgctccaga
     5821 tactggcaca ggttcaggag gagcttctga tgcagatagc caacaatccg aaacagatgg
     5881 agaaccatct agtgaagaca gctttaaagc tccacagtcg caatcagagt tagatagcta
     5941 tacgaataaa gcaatccaaa aggcattgga aaatcaacgc aaagatgaag ctaaacgaat
     6001 agaagaagct gtaaaagctg ctttagataa agaaaaagac tactccaagc tatctgaaga
     6061 agaacgtcag cagcgtgaat ttgaagatag taagaaagcc tttgaagctg aaaaagccaa
     6121 gtttgaacac gataaacttg tagtccaagt cgaaaaggat cttatcgcaa agggattgcc
     6181 ttctgagttt gctgaattgc ttgctacaaa agatgcagaa aatgcgctag agcaagtcaa
     6241 aacattcgaa gcagcattta aaaaagcagt agctgatgaa gttaaaaaga ccgtacgaca
     6301 acttactcca tcaactgggg caggtgcaat atcaacacaa acaaactatg gggcgaactt
     6361 ggcgagtaag atcgcacaac aaagcaccac attattttag gaggaaaaaa atgaataaac
     6421 gtaaagtaac aacatcaaaa gagattctcc acaatctcga atacgaagct attacagtca
     6481 ctttagattc aagcacagtt ggcaaaaaag ttattccagc cggtacagtt ttggccggtg
     6541 tatcggattc tgtttttaaa gatcgcaaac aaaaagtaaa aactgtggca aatcacgagg
     6601 tcagcggaga gagcaatatt tgtggaattt tgttaaccga tgttgatttg acagatggtg
     6661 ataaagcagg tgcttgtgtt tatcgcggta ctgtcaacgc agataaactt gctgattcat
     6721 caattgcaga aaattttacg gaattggcga caaaactacc acatgttgtc tttattaagg
     6781 gaggtaagta agcatggcat tgatccacga aattatcaca tcggaaaaca tcaaaggttt
     6841 ttataatgct aaaaatgaga acattgataa aacgttaggg gaaaaagcat tcccaccaaa
     6901 acagcaatta gggcttaagc tatcctttat caagggtgcg gcaggaaaac ctgtgacact
     6961 taaagcggcc gcttttgata ctaaagtacc tctacgtgac cgcatggcag ttgagctgct
     7021 tgacgaagaa atgccttact ttaaagaggc tatgcttgtt aaagaggcag accgtcaaga
     7081 gcttaacatt atatctcaaa caaaaaatag tgatcttatt gacacagttt tagcggcaat
     7141 ttataacgat aaggtaacgc ttatcgcagg cgctaaagca cgtttagaag caatgcgtat
     7201 ggaagtgctg tctaaaggta aaatccacgt cgcatcaaac ggtgtcatga aagactttga
     7261 ttatggacta gactcttcgc aaacaactaa gccaagtgtt aaatggtctg aggcagagac
     7321 cgcgacacca cttaaagaca ttgaaggtgc aattgaaaaa atggcagaac gtggctttgt
     7381 gccagaagca attatcatga actctaagac atttagtttg attaaaaacg ctaaatcaac
     7441 tcttaaaatc atcaaaccaa tggcaccaga tggggcagct gttaccaaag gtgatttgac
     7501 gacttatatt gctgatgaac taggactcaa aattttgttt aaagatggta tgttcattgg
     7561 tgacgatggc aaatctcgta agtatttccc agatggcttt gcaactttgg tacctaacgg
     7621 caaccttggc tacactgtgt ttggcactac tccagagcaa tcagatctca tgggtgggca
     7681 cgcaacagat gcagatgtgt cgttggttga gactggtatt gcaatcacaa ctactaagac
     7741 aactgatcca gtaaatgttc aaaccaaggt atctatgatt gctttgccgt cattcgaacg
     7801 attggaagaa gtgcaaatta tcgactccat tgaccaagta taaggagggg gttatggctg
     7861 aagttattaa aacttttagg gataaagaaa ccactaacac ttactacgta ggagacgatt
     7921 acaacggaga ccgcattgat gagttgacag ctaaaggata cctatctggt gataaggttt
     7981 ctgctgccgc tatagagatt gaccttgaca aattaaaggt tgacgaaatt agagcaaaac
     8041 ttgatgagtt aggcgtcgct catgacccta aactaaaaaa gccagaatta ttagaacttt
     8101 tgaaacagtc agctagctag gaggtgttta tgcaaaagat aaacacagat agcattatag
     8161 ctaacgtaaa actcgattta ggtattgatg acaccttgca agacagtttg ctcaatatgt
     8221 tgctaaaacg tgttacagac cattttaaag cggaatacgg cgttgatgat atagacaacg
     8281 ccttttcgtt tgttttggaa gactgtctaa ttgctaggtt taatcgcaga gggtcagaga
     8341 gggctaagtc ggaagaggta gagggtcata aaacaaccta ctatgacttt ttaaatgagt
     8401 ttgagcctta cgacaaaatg attaagtcca accttaattt gattaaggat aattctcgta
     8461 aagggggatt gtacttttta tgagatatgc agataggatt acgtttgtta aggcgacaga
     8521 tgaacaatat gaccctgatt taggtgagta cacatatacc gaagtcatga tcaagacatt
     8581 gccttgtttt gtcatggact taggtatggc taaatctgtg cagattttcg gagactatca
     8641 aaaaacacga aaagttgttt atttgcgcca accttatacc gatttgttag atcactgtct
     8701 ctacaaaggc aaaaagtaca aggtacaggt ggataagcaa tttaatactg ttttttatct
     8761 ggagggagat gattctattt gtagctgata tatctttaaa agtagttgga acgacagggc
     8821 taaagaataa acttgaactt attgccaaaa aagaggctgt caagaagatt gttagagata
     8881 atggaaaaca actacacagg aaaatggtcc aaaaggcagt atttaccaaa ggtcattcca
     8941 ctggtgctac cagaatatcc atcacaatgc agattggtga tgatggtttt agtgttacag
     9001 taaaacctgg cacgcattat gcaggttatt tagaaaaagg cactcgcttt atgagtaagc
     9061 aaccttttgt gttgccagct ctaaaagagc aaaaagtaaa attcagaaaa gatttggagg
     9121 cgcttgtcaa atgattaaaa ctagagatca atctattttt gacgagatgt ttaagcgtat
     9181 tcagtcttta ggttttaaag tttatgatta caaaccgatg actgaggttc cttatccgtt
     9241 tgtggaaatg gaatctactg atgcagaata tattccaaat aaagatgaca ttaaaggctc
     9301 tgttgacctc gtactgtctg tttggggatt gcaaaaaaaa cgaaagcagg tgtctgatat
     9361 ggcatctgct attttttcac aagctatgtc agtggctagt tctgacagct tttactggtc
     9421 gttaaatatt cgtcaatcat ctatccaagt gttagatgac acaacaacag tgacacctct
     9481 caagagagcg attgtcacat taagatttaa tttaagatag gaggtcgcaa tgccaggacc
     9541 aagtagatta ggatccaaag atgaagacca ctccacacaa gaaaggaagg aaaaaatggc
     9601 agcgcaagat caagtacaat tagaagcaaa acaagggatt catgcaatcc tattattccg
     9661 tttgttaaaa gaagcatcat cagaaaaagc agctaaactc gcttttcaaa cggaacacga
     9721 agttggtaaa agtcgtgatg tcgacggtca aaagactaaa gatggtatta tccagtctgt
     9781 cggagcttta gaatacgact ttaaagcaac atctatttta gccaaaggtg acaagttagc
     9841 agcaaaacta gaagaagcca tggaaaaagg tgagcttgtt gaaatttggg atattgattc
     9901 cgaaaaagca agtgaagaag cttgatagca aaggtaaata tccagctacc tattaccaag
     9961 gttacatttc aagtttcggc gctaagaaaa atgcagaaga aaatattgaa attgaaatgg
    10021 aatttgccat taatggcgtt ggtcaaaaag gatttgcaac attgaccgaa gaacaaaaag
    10081 cagctgtaca gtacaaattt aaagatacaa cagcaggtta atcaacaagg ccagttaatt
    10141 actggtcttt tatttttaaa tttttaaagg gggaaaagaa taatgcaatt ggaaattaaa
    10201 ggtaaaactc ataacatcaa atttggcaca cgatttgttg ctgaaatgga taagaatcac
    10261 attgcagaac gtgaagggat gaagtttggc gctggtttgc aatcaactgt tccgtttttg
    10321 tttgagcgta acgttgtgac acttgctgag attatctata cagggacaat cacagagtca
    10381 ccacgaccaa gcttaaatga tatttacgac tacatcgatg aggctgaaga tattgagaag
    10441 cttttcgatg atgttttaga tgagttgcgc caatctaacg cgtcaaagtt gtttatcacc
    10501 aaactggaca aaaacatagc ggagatggca accgaagctt aaagagttca accaaaaatt
    10561 attcttcaca agaaagcttt gagatgattg tccttaattg tgttagatat cttggcatga
    10621 ctgacattaa tgagattggt cggttgactt tgtatgaata tgatttattg atgataggta
    10681 aagcgctagc ctctgtagac gaggcatata aagctcacaa gcaagcttgg ataaatcacc
    10741 aggtctcagc tacgaggctg gtcggtggtg gtaaaaacaa aagagaagtt cctgtttata
    10801 aaacattcaa ggaatttttt gattatgaaa cagaaatcaa gaagataacc aatgaaattg
    10861 atgaaagcta tgacaagaaa gcaatggatt tacttttaaa agccaacctt taaatagaaa
    10921 ggaagttaaa tgggagaatc ttattcagtt gaagcggtgt tgacagcggt tgataaaacc
    10981 tttggtaaga ctttaaaatc agcagttcaa tcaattgaag gactagaaaa gcgttcaaaa
    11041 ggcttctcgg cggtgtctca aaaggctggg tctatgttta aaagcatgct tggagctaac
    11101 ttagcaggtc aagctattac agcgctagga cgtacagttt catctggact tatttcgatg
    11161 atcggcgaaa tgaatagctc agcaaaagcg tggaaaactt tcgatgccaa tttagcagat
    11221 atcggatttg gcaaacagca aattcttgaa gctaaaacag ctatgcaaga ttacgctact
    11281 aaaacaatct actcagcatc agatatggcc agcacatatg cacagttagc tgctgttggg
    11341 gtaaaggata ctgggaaact cgtaaaagct tttggtggtt tggctgcatc tgctgaaaat
    11401 ccaaaacaag ctatgaagtc aatcagtcag cagatgacac aagctgtggg aagacctaca
    11461 gtagcgtggc aagatttcag aataatgctc gagcaagctc cagctggtat ggctaaagtg
    11521 gccaaagcta tgggcaaaaa ccttaatgaa cttgtagccg acattcaggc tggtagagta
    11581 aaaactaaag acttcctaga agcagtaaaa caagctggta acgacaaaag cttccagaag
    11641 atggcgactg aattcaaaac tgtggaccaa gccattgatg gcatgcgtga aggtttatcc
    11701 aataaattgc aaccagcttt tgaaaaagtg aaccaatttg gaattagagc gattgaagca
    11761 atcgggaaac aactcgataa aatcaatttt tccaaatttg ctgcaggcct tggtaaattt
    11821 ctcgagggcg tgaacattga tagtattatt tcaagaatat caacatcaat ttcatctatc
    11881 gtttctaaaa taaaaggatt ctgggacgga tttaatcaaa ctggagcaat cagcgctttt
    11941 tccggtgctt tacaaagtgt ttggggagcg ttaaaaaata ctgctaaagc catgagtgga
    12001 ggaagctgga agaccttcgg gtcaatcatt ggcgaaattg ttaaacatgt ttctaatttc
    12061 gcaagagtga ttggagatgt cgttggcaag atggatccga gtagactaaa aagctggata
    12121 gctactcttg cagctgttgg tggtggattg aaaatctttg agaaattaac aggtcaaagt
    12181 gttattggat cttttttaga caaaatcggc tcaaaattca aaatatttgg aaataaagcc
    12241 aaagaaggga cagaacaagc ctttaacgga gtcaaaagaa gtggtggcat tatcagtaaa
    12301 atctttaacg gtttgggtaa tatcgttaag tctgccggta cagcgatagc gactgctgca
    12361 aaaggtatcg caactggttt ttctatcgcg tttaaggggc ttgggtctgc catttctatg
    12421 gtaccgccag ctacatggct agctttagga gcagctattt tagcggtagg agcggctttt
    12481 gccttggcag gaactcaagc tgatggcatt agtcaaattt ttaaaactgt tggcgatgtc
    12541 gttgtacaag ttttacaaca ggtcactaac agtctagcta ctctaattcc tattattgta
    12601 agcgctattg gctccatatt accaattgta gcaggggcta tttctcaagt cgtcgcagca
    12661 gttgctggcg gattatctca gattattaca gctgttgcta atggtgtatc aactattatt
    12721 ggggctttca caggtctact tggtggtgtt tctagcgtca ttacctcaat tagtggtgtt
    12781 atccaatcgc tggcaggtgt aattacctca gtatttaatg gcatagcaac cattatttcg
    12841 tctgtagggt ctgcaattaa agatgtatta acgggtctcg gcagtgcttt taaaggattc
    12901 ggcaacggtg taaaatcagc cttagaaggc gttgggacag taatcaaatc atttggtagt
    12961 gcagtcagaa atgtccttga tggtgttgcg catattttcg attctatggg taatgcagct
    13021 cttaatgctg gtcgtggcgt caaagaaatg gctaaaggca tcaagatgct tgtagattta
    13081 tcgcttgctg atttagtcgc aacgcttgga gcagtcgcga caggtcttgg gaatatggct
    13141 ggctctgccg gtcagatgac tacgttaagt tctgccatga gcgaagtagc caatggtatg
    13201 gcgcgtctag gaacaagcgc tacgatagca attactggat taacagtttt tgctactact
    13261 ataacaacta ttcagaccgc aattgcaact ctaccaacaa tcctaactgc agccgctagt
    13321 ggttttaggg agatcgggga ttcggcaact gcagcagttg gtcgaatcca gacttttgca
    13381 gctggtacaa ctgttgttgc atcagcgttt gctagtatgc aatctatgat tcgatctgcc
    13441 atggctgcaa tagtaagcag cattataaca tcatttaacc aagctgcctc tcaaatacaa
    13501 tcaattttat ctcgggtgct atctcaagct aggacatttg gatctcaact agagcaacaa
    13561 atgaggcaat cgggacagcg ttcaggacaa aatcttgctc aggggttgtc ttctcaacaa
    13621 ggtgctgtta ttaatgctgt ttctagcatg gttaatgccg cggtatcaag agcaaatgca
    13681 ggtgctagtc ctatgcgtca agctggagcg tacatcggac aagggcttgc gcaaggtatg
    13741 tattcagcgc taggagctgt aacagcagca gcaaacgctc ttgtagcaca agctgagagg
    13801 gcagcaagag ctaaggcgat gattcactcg ccatctaggt tatttgcaaa acgagttggt
    13861 caatatatcc ctcaaggggt agccatgggg atatataaaa acgctgatgt cgttgatgat
    13921 tctgtaggtg agctatttga tagtatcaat agctttgatt ttaatattgc ggatagattg
    13981 acaagtattg gcgctagatt ccaaggtgtt gtcaaatcag aaagttcgca atcgttgtcg
    14041 cagcaacaag agtttgtaca tacagctcaa ccagcgtatg taaactttag tttaggcgga
    14101 aacgaatacg aagcatttgt aagtgacatc actaatcgac aagcaaaaat tgaaaaaatc
    14161 agactaaaga gaagcagctg gtagttgttt ctcttagttt tatgaaagga gtaaaatgta
    14221 cgaatttaac gatactatca gagggactcc gaaagttact ttcaatttaa aaacaacaat
    14281 tggcgaaaag gtattagaag aagagctcaa taatgattta ggtaccttta ggacattgac
    14341 cgtttctggt cgtgatatgg tggacttaga acaccagaca acaagtgttt tagggcgaga
    14401 tggcgagtat ttccacaatg ccacagttga agtcagaaaa ctagaaataa aagctaaaat
    14461 tactggaaaa gataaccggt caatgcgttt gcaatatgaa aaattaaaca gattaattgt
    14521 tagtcataat caagtttttt tatcattttc agacgagccg gacagaaatt atctaggcat
    14581 ctttaaatct aaagatatac cagaagaagt ttctaacgaa caaatcattg gcttggtttt
    14641 catctgttat gatccattta aaatgtcaga tataaaaacc aaaaaaggta atactgttca
    14701 aaatgatggc ctatttaata caaaacctat cataactctc aacctctcat catcaacaaa
    14761 agaaattagg ctgctacacg tcgaaagtca aaagtatatc agattaactg gtacttatac
    14821 tactgacgaa atcaagattg atatgacaac aggtaagatt acccagaacg gccgtaatat
    14881 tcttagtgat ttagacatgg ttaacagtcg ctattttgat ctattacctg gtaaaaacac
    14941 tttgcagtgt gataatgcaa cgattacagc tgatttcagg gaggtttatc tatgatttat
    15001 ctctttgata agctggagca attagttgct actgttggta ctgatgactt gctctcatgg
    15061 cattttaagg tcaaaaataa tgattgggat caagctagtt ttgaggtacc tgttgattat
    15121 gacattgagc cttttgttta ctttggtttt tttaactatg atccaagcca aaaagaggac
    15181 gtttttaaac tctttaaagt cattgattac aacctagaag atagcaagta ttataaaggc
    15241 ttagataagg ctgagagtga ccttgatact attgctatta tcaaagacaa gcgctttaga
    15301 caatcgtccg cagatgcttg tattgatgga gctttagagg gcactggtta tcaagttggt
    15361 aaagttgagg gcatttccga gatcaggacc cttagctatt attacatcag cccacgagct
    15421 gccatgatca agatgataga agcttttaac tgcgaattta atgtcagata cacctttgtt
    15481 aataacaaaa ttactagtcg ctatatcgac cttaaaaagc gatttggcaa gccaacagga
    15541 aagcagtttg agcatgggaa taacttatta aaagtcgtct atgaggaatc aacagatgac
    15601 atcgtgactt gtctgattgg ccgaggcaag ggcgaggaaa tccaatatga tgaaccagag
    15661 gcaaaggaag ttgaaggaca cttaccagag gcagaaaagc gtcaaggtta tggccgaaga
    15721 attgaattta gcgatgttgt ctggtcagtc gaaaaaggcg actcgataga caaaccagct
    15781 ggtcaaaact ttgtggcgct agatagtgcc agagaagaat acggattgtc tcaaaatggc
    15841 gagctaaaac accgatgggg ggtctttgtc aacgaggaaa ttgaggacaa ggcggaactc
    15901 ttaaaagcca catgggatca attgcagcgc ttatcaatac ccatcagaat ttacaaggcg
    15961 gaaatcttag atattggccc cgaaacgtgg aaaggtgact cagtagccat tatctacgat
    16021 gaggtaaaaa tagcttttga aactcgtgtt gatgagattg atattgataa gctaaacttt
    16081 aacaggtcgg tagtaactct cggtgattat agcgttgtcc aaaaccgcga agcaaggtca
    16141 cgcaaggaag ctgtccaaaa catgatcaat gatagcatag aaaacatcac cggccttggc
    16201 atgaacttac aagaattttt tcaaggtatt gaggaaaaaa ttgccactgg caaaaaagag
    16261 atggaagaca attggcgtaa ggttaacctt gaatttgata actttaaaaa attaatcgaa
    16321 caagagggac gtaactttag agagcgttta gaagctgaaa caaaggaact agatgaacgc
    16381 aaccaaaaag aactcgatga atttcgcgaa accctcaaaa atctgtcgct gcccgaggaa
    16441 gccattaaaa aaataaccga ggccatcaaa gttgatgata tcccatcgct aaaacaaagt
    16501 tttgacgagc tcaaaaacga agtcagcaag aacagcgaaa aatctcgctt aaatgctgaa
    16561 atcatcggca cgaacggtaa gacccgctat aacaaaaatc tcttggttgg tgaacctaat
    16621 cgcaccaaga cctatgatca ggattttgtg gagatagaag caaatgacgg tggttttaga
    16681 cgcggtgaga catacacgat tagctttagt cagacatgtg agttgctaaa aaaagtggct
    16741 atcacgctga cgcagccgca taacaaaggt ctcaagctgg tgctgacacc aaccaaggct
    16801 aagatggagg cgcagacttt tgacctaacc aaggacatag aggttatcag cgtctatcct
    16861 ttgagctaca gagctgtttt aacaggtgac tggtataaat ctaagcagat ggattttaat
    16921 gcggcagaag tgcaggattt agctctggag atgtcttata gagacgttgt cgatagcaat
    16981 aatgctagtt tgattttgga ttggtcctca aatccagatg ttatttttga tggaaatgga
    17041 ggtagttaat gtcagagact atatcagcta tagttgtgca taaaagcatg acaaaaaacg
    17101 agtgggagtc tagtgacatc attttgccac aaggccagct tgtctatgag tctgacacag
    17161 gccatagtaa atttggcgac ggtaaaaata gatatgcaga tttgatctat caaggtggac
    17221 cacctggggc acaaggtccc caagggccag ctggcgaaac cggtccacaa ggcccaccag
    17281 gccctactgg tcaacgtggg gaaacaggcc cacagggtcc acctgggcca caagggccgc
    17341 caggagcgga cggtaaaatg acgtttgagc agctcacacc agagcaaaaa cagcagctta
    17401 aaggtgctgg catacaaagc atatcattgg attatgaggg ctatttgaca atacagctag
    17461 ataatggcca atcgtttaga tcagatatta gcttaaaagg tcctcaagga gagccgggga
    17521 tcaatggtat ggacggtcca agaggcgcaa cgggtcccca aggaccagct ggtgatccgg
    17581 cgagcatacc tgacgatgtt gtcagacgtg gtgagttagc tgcatatttg cttaaatcag
    17641 agtataaagc caaaggcgca ggctctgggc taagctacaa agttgtcact caatcagagt
    17701 atgatgatct gtatgattac agcgacaatg agttgatact cgtgacggag ggttgacatg
    17761 gcatataagc tttacactaa agctgatgtt ggtgacaaca tgttgcttgt tgttggccat
    17821 ttgcctgaca atacaaagcg attaaaaatc cagcgtgaga cgttagatgt attgagtatt
    17881 acccactata gctcttatga tatggtacaa ctcaagtcga cagtcaaaag atcccacagc
    17941 aaaaatacag ttgttactct tgtagctgca gctgctagca agcccaaagc taagccaaag
    18001 cacgttttaa actttgctaa ggctaataag gtctatctag gcagcactcg tgtaatagcg
    18061 gtttatctgg gtgatcgact gctctggtcc gacaaagaca gcagcgggaa caaaactgtc
    18121 tctgttgtgg ggagtcttga tatcagacaa tcacaaaaaa tgctgtattt gtacttaata
    18181 gcgtcagaca ttgcagatgt caaaagcaag cgcattaaat cgatagcgat aaatggcgtt
    18241 aacctgtcaa gcgctgcaca aatcaatttt gaggatagcg actattattg tctagtgaca
    18301 atcgagcgag ttgctaacat caaagagatc aaaaatatag cgcaaaaaaa caaaatcacg
    18361 ctagagtttt aggaggtaac aattgagcag agacccaaca attgtaatag acgagacaaa
    18421 cctcgttatt ggcacagatg gccgcatgca ttacacgttt actgctagtc aagacaacca
    18481 aaaggtcagg ctaaaaagca actgtttagg cacagcgcat tttaaccagc tgatgattga
    18541 gcgaggagac caagcgacgg actacgttgc gcccgttgtt gttgagggta caggacaggc
    18601 aacaggcgtc tttaaaagtc tcgaggagat gcttagtggc ctaaagtcaa ttaaactgga
    18661 gctaacagat accaaaaact caaatctgtg gtcaaaaatc aaattgacga caaatgggct
    18721 tttgcgtgag tatcatcatg atcatatctc gaccgagatt gtcgagacag cagctggtat
    18781 tgccaaacgg attgtcgatg atactggcca aaagctggca ctaatcaatg agactatcaa
    18841 aggtgttaag cgtgagtatc aagacgcaga tagacagcta tccgcgagct atcaagcaag
    18901 tatcgatggc ctcaaagccc agctggccaa cgacaaaatt ggcctacaag ctgagattaa
    18961 gctgtccgcc caaggcttgt cgcaaaaata cgacgatgag ctgcgcaagc tatctgccaa
    19021 gattacaacg acatctagtg gtactacgga agcctacgaa aacaaactcg agggcttacg
    19081 ggctgagttt actcgtagca accaaggcat gcggacagag cttgagtcgc aaatcagcgg
    19141 cctaaaagca gtacagcaat caactgcaaa acaaatctca caagagatca aggatagggc
    19201 aggggctgtt agtcgtgtgc aacaggatct agatagttac caaagacgct tgcaagacgc
    19261 agaggataat tacagtagct taacccagac cgttaaaggc ctgcagtcaa ctgttagcga
    19321 tcccaaaggc aaaatccagt cac
//
LOCUS       DARYMD010000037        18621 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYMD010000037 DARYMD010000000
VERSION     DARYMD010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18621
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..654)
                     /locus_tag="TU818_001369"
     CDS             complement(<1..654)
                     /locus_tag="TU818_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HEL0924181.1"
                     /translation="MDEIKLYENKEIRSIWDEEKEEWYFSVVDVVGVLTEQENVRGAS
                     TYWAVLKKRLKEEGNELLTICKQLKMKATDGKMRLTDVADMQGIFRIIQSIPSPKAEP
                     FKLWLAEVGKERIDEIIDPELTIDRALETYLKKGYTREWINQRLQAIQVRKELTDAWD
                     DHGIQKGKEYAILTDEITKAWSGMTTRGYKNLKGLKKENLRDNMTTLEIVLNMLAEAT
                     "
     gene            complement(750..1715)
                     /locus_tag="TU818_001370"
     CDS             complement(750..1715)
                     /locus_tag="TU818_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL0924182.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEIIEKALEIYFKEYIGQ"
     gene            complement(1708..2484)
                     /locus_tag="TU818_001371"
     CDS             complement(1708..2484)
                     /locus_tag="TU818_001371"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL0924183.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            complement(2636..3799)
                     /locus_tag="TU818_001372"
                     /pseudo
     CDS             complement(2636..3799)
                     /locus_tag="TU818_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(3801..5522)
                     /locus_tag="TU818_001373"
     CDS             complement(3801..5522)
                     /locus_tag="TU818_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924184.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            5971..7977
                     /locus_tag="TU818_001374"
     CDS             5971..7977
                     /locus_tag="TU818_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL0924185.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            complement(8168..8578)
                     /locus_tag="TU818_001375"
     CDS             complement(8168..8578)
                     /locus_tag="TU818_001375"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL0924186.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(8710..10059)
                     /gene="gdhA"
                     /locus_tag="TU818_001376"
     CDS             complement(8710..10059)
                     /gene="gdhA"
                     /locus_tag="TU818_001376"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL0924187.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            complement(10200..11976)
                     /locus_tag="TU818_001377"
                     /pseudo
     CDS             complement(10200..11976)
                     /locus_tag="TU818_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(11976..13721)
                     /locus_tag="TU818_001378"
     CDS             complement(11976..13721)
                     /locus_tag="TU818_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924188.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISISKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            complement(13826..15693)
                     /locus_tag="TU818_001379"
                     /pseudo
     CDS             complement(13826..15693)
                     /locus_tag="TU818_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            complement(15686..16897)
                     /locus_tag="TU818_001380"
     CDS             complement(15686..16897)
                     /locus_tag="TU818_001380"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL0924189.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            complement(16997..17845)
                     /locus_tag="TU818_001381"
     CDS             complement(16997..17845)
                     /locus_tag="TU818_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0924190.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            complement(17845..18225)
                     /locus_tag="TU818_001382"
     CDS             complement(17845..18225)
                     /locus_tag="TU818_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL0924191.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            complement(18430..>18621)
                     /locus_tag="TU818_001383"
     CDS             complement(18430..>18621)
                     /locus_tag="TU818_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEL0924192.1"
                     /translation="NGMMESFFGILKSEMFYGFEKSYHSLDELEQAITEYIFYYNNKR
                     IKTKLKGLSPVQYRTKSFQ"
BASE COUNT         5432 a         4336 c         3303 g         5550 t
ORIGIN      
        1 tgtggcttct gcaagcatat taagaactat ttcaagagtg gtcatattat cccttagatt
       61 ttcctttttc aaacccttca gatttttata acctcttgtt gtcattccgg accatgcttt
      121 ggtgatttca tcagtaagaa ttgcgtattc tttgcctttt tgtatcccat ggtcatccca
      181 agcatcagtc agttcttttc ttacctgaat ggcttgaagt ctttgattta tccactcacg
      241 tgtatatccc ttctttagat aagtttctaa ggctctgtca atcgtaagtt caggatcgat
      301 aatttcatca attcgttctt ttccaacctc agcaagccat aacttaaaag gttctgcttt
      361 aggggatggg atggactgga taatacggaa tattccttgc atatctgcta catcagttaa
      421 acgcattttt ccatctgttg ctttcatttt caactgctta caaattgtaa gcagttcatt
      481 tccttcttct tttaatctct tttttagtac agcccaatag gtactagcac ctcttacgtt
      541 ttcttgttct gtcaaaactc caactacatc gactactgaa aaataccact cttctttttc
      601 ttcgtcccaa atggagcgta tctctttatt ttcatacaat tttatttcgt ccattctgac
      661 acctgcctct tttatatctt atcctgttaa acaggtcttt tcccttttta ataccttata
      721 ttatacctta aatttataat tttgtctttt cactgaccaa tatattcctt aaagtaaatt
      781 tccaatgctt tttctataat ttcttctaca tcttctttcc tttcatcatg aaaaaacttt
      841 ttatagacac tctgagatag tttgatattc tgatactttt ttaccttcgt ttttttcaag
      901 ttcagcaagt atgttataac catctcttga ttcagatctt cttgtctgtt catcagatgg
      961 agtgctttgg catcgcttgg ttttaaactt agttccaatt cttcgcactt ctgatacaga
     1021 tattcctgta tttctttgga aagataggat aaatctactg ccatcgtcaa acctatttta
     1081 tcttcatcca catctttttt ccaagactta gataattcat ttaatcttag gtaccttgca
     1141 atagatgccc ctgaaagatt atattctttt ccaagtgttt ttctgctgtc tattttatct
     1201 tcctctttac tttccttttc tataattccc tgatctaaat tgtttatctc cttttgcaaa
     1261 tcatttctct tgccctgact tgctattttt tcatatctca ttttaagaac aagggctttt
     1321 tccgtcggca gtaaatcgga gaaagaacgc tgtataaggt ttgtttcaat tacataggta
     1381 taggcttctt tatccgttag attttcttta acaatacaag gaatactttt tatttttgta
     1441 attcttgctg catttactct attgtgtccg gaaagtattt catagttgtt atcttttttc
     1501 aagacgataa ttggattaag aactccgttt tccttaatgc tctctaccat atcgtctaat
     1561 ctcttacctg tatataaagt aaacggatga ttatgataat tttcaagcaa atcaagttct
     1621 atattctgta tatttccttg ttccaaggca tttccatcat caagcaaaaa atctacggca
     1681 tcggtgattt ctctctttag aagtttttta ctcatagcag atctcctttg ccagattgtc
     1741 ataggcaatg tctacactac tgccttttgc atattttttt atgctttgcc cgctatagat
     1801 ggcttcccca actttaactg ttttcggaat tttggtttga aagaccttga ttttcttttg
     1861 gaacatttct tctacttgct ccatcagtgt tttggacaga ttggttctat tctcacacat
     1921 ggttagtaaa atcccctgca ctttcagttt cggattcact ctctttttta ttttttgaac
     1981 agtttttaaa agttcattga ttccaacaac tgcgaacagc tgtgtatccg ctactataag
     2041 gacactgtct gaggcacaaa gagcatttat agtcaaaaca ctaagtgatg gtgatgtatc
     2101 tatgagaata tagtcataat tctcttttac cctcctaata atttccgata atatacgttc
     2161 acttcctgtt tctgctctca tttgtgtttc aacggcggat aagaaaatgc ttgaggggat
     2221 aatatctatc tcatcataag atttggtata gccctctacc aaatagcttt cttcttcctc
     2281 cagttctacc attaacaaat gccctatggt ttttatattt tctgtatttc ccatatcaaa
     2341 acatcttgta agattagctt gtggatcaag gtcaatgact aatacttttt tccccagttc
     2401 ttttagtgaa taggcaaggt ttagagttgt agttgttttt ccaactccgc cttttcgatt
     2461 ggctatggtt atcacttctg ccataaagtc cctccttctt ctctatacag agatttcatt
     2521 ttatgctata cttttatata attttagata taaaaaaaga tgatagcctc aatccatcat
     2581 caagtttaaa agttttgcgg aagcctttaa ccattgattt tacttggatt tattgtacta
     2641 tcatcattat agcattgtcc ccagagccag tatgccctac tagggcaacc gtctcccctt
     2701 tatcagcatg aatggtaata tcagataaaa ctgtcttgcc attttcgtaa gcaaaataca
     2761 ccttggtaaa atccacagta ccatctgtta gctcaattgc tcgtgcttta tccggctctg
     2821 tctgcgcctc aagcagcttc attaggcgcg ttcctgtcgc tgttgagcgc tgaatattag
     2881 gtagctgcct aaccagcata cttaataaat caaacaagcg cagcaaataa ttgacgtaaa
     2941 taaagagctt accaactgtg atgcctgatc tcccctgcaa gaactggtaa ccaataacag
     3001 ccaaaatagc ggcaatcatg ccatacttta ccaattccgt cagggtccat gaagcaactg
     3061 actctgcaaa aataatccta tcatcagctg ttttcatctg gtggatctgc tcttcaaatt
     3121 cctctaagat cgtatcctct tgatgataaa gctgaataat agaaacacca ttcatggttt
     3181 cgttgacttg tgtgttgaca gcgctcctag cctgataaaa atccttcatt ggctggtcag
     3241 tcaagctttt atacagccat tgcatgccat aaaagagtgg cataataagc agcaacagca
     3301 agcctgactt cacatcaagg taaatcatca ccacataaat aaaaataatt tgtgaaagac
     3361 tgacaataat ttgagacaaa aggttatcat aaaattgatt cttcagggtt tcagtatcat
     3421 taacaatcct agttgcaatc tttcctgcag gctgatgatc aaaataagct atcggcagcc
     3481 tctgcatgac atcaaaggct cgattacgaa gattagcaac gatcctatta gaggaataaa
     3541 ccagcattcg ataagagata taacgcaaaa ctgctgttat cacaattaac agcaaataca
     3601 gcaggagcaa gcgctgaaag ccttcaatcg gtacctcttt tcctctagct atcggagtca
     3661 agtaatgatc aatcgtttgt tgcaacaata agggagccat ctgacctcca gctgttgcca
     3721 ctagcaaaaa gcctattgcc agggaaaaag ccaaggtcac agctttaatt tcttttatta
     3781 attttataaa tagggtcatc ttaaacctcc tgagcctgct gacgctggta ctgttcataa
     3841 taccagccct tctgagctaa aagttgttgg ggctgacctt cctctactat ctgcccctga
     3901 tccagaacaa taacccaatc ggcatgctga atcgcagaca agcgatggct aacaataagt
     3961 gttgtctttc cctttctttc gtcttgaatg tgtcgaataa tatcagtctc tgttctagca
     4021 tcaactgccg acagggaatc atctaaaatc agcaaatctg gctgggacaa aaaggctctg
     4081 gcaatcgaaa tacgctgctt ttgacctcct gaaatagaca gaccacgctc tccaatctca
     4141 gtatccaagc cctttgccat tccttgaaca tcacgcgtaa aggccgcagt ttcaatcgcc
     4201 tccaagattt cctcagttgt agctgccttt ttccccatcg caatgttttg agcaaccgtt
     4261 tttgaaaaca ggatatgctc ctgtggcaca tagccaattt gacgctcaag tgattgacgc
     4321 ttataatcca agacactacg atgattaatc atcagctgcc cctgcccaag agggtattgt
     4381 ctcaaaaact gcctgacaag ggttgtttta ccagagcctg ttttaccaac aatccctaag
     4441 gtttgtccct ttttcagggt taaattgatc ttttctaagc taggcctaga actattggca
     4501 taggtaaagc tatagtctat aaaagcaatc tgatcaaagc tctctaactc aagctggcca
     4561 tcaggctcca tatcatcact tgtttcgatg agttcattaa tcttaccaaa agaggtcttt
     4621 cctgtctgat aaaccaaaat aaagtctgac agcatgccaa agggctccac caaagacacc
     4681 agataaagct gcagcgcaat gacttgacca agtgttacct ctgagcttgc tatgagctgt
     4741 aggcctacca ttaaaatgat tactgtacta atggcaatca tgacgctgta aagaggaaag
     4801 tacaaggcac gatacttggc cacctgattc catttatctg ccaaattctg agtcttttga
     4861 gcaaaatgaa gtgccaaata atctttttta ctgtaagcac gcatcactct aatgccctca
     4921 acggtttcta gtacctcatc actaaggctt gaaatcgcct cacgcgcctc ttcaaccaaa
     4981 tgctcttgct ttttcgtcac accatagatc atcaccatca taagcaaaat cggtactatt
     5041 cctatcaagg tcattttcca agaaatcaaa aacatggtcg gaataataaa agcaatcata
     5101 ccaccagcat ataggataat catcaagcca tagccgataa ggtccataag tgcttcgaca
     5161 tctgttgaaa aacgcgtgat catgtcacct gagcgaaatt tctcataaaa aggcgttctc
     5221 ataaaaacaa gctttcgaaa ggcacgctgc tgaatatcaa acttaaaatg aactgcctcc
     5281 tgaaataaat gaagatgcca caaataagca accccataag acactactgc cgtagccaaa
     5341 agaatgataa catgcctcac caatgcccct gagcttagct gatgccttga catcaaatca
     5401 accaagtctt gaataaccct tgttggtatc acaagtgagg catcatatat cactaaagtc
     5461 attgcaataa ggatataaat ccatttcttt tgcttaatat gttgaacaat taaggtcagc
     5521 atcatatcct ccatttctga actaacctat ttcaagctgt cttaaaatag gatttttgca
     5581 cacaaaaagc ccgcaataag atatccttcc taccgcgggc tctactattt ctatttagtg
     5641 aaactaaaag aaactaactg ttttggttag aaaggagact atcgtaataa tggttaaata
     5701 gttgaatgaa acggatcatt attaatttct cctttctttt aatctgccta acatcttatc
     5761 atagaatact gggcttgtaa agcctttttt ggatagttct tctatttttt tacaaaaaac
     5821 gcttccaatg tttgcatttt aaacgttttc agtgattagc aaacgctatc gttgaatttt
     5881 tgttagcttt tttattaatt tttgttgaat tctcatttaa ataatagtac acttaacttg
     5941 tgacaatact ttaaactttt aggagcgttt atgaaaaagc attttgtttt aaaaagtagt
     6001 gttcttggtg tctttgccgg agtttctatg ctagtaaccg gcgtgcaggc cgatcaggta
     6061 gacgtgcaat ttcttggtgt caatgacttt catggtgcct tagacacaac cggctctgcc
     6121 tacatgccag aaggaaaggt atctaacgct ggtaccgcag cacaattagc tgcttatctg
     6181 gacgatgcag aggctgactt taagcaaaca agcccagatg ggacaagcat tcgtgttcaa
     6241 ccaggagata tggtcggagc tagtcctgct aattctggac tattacagga cgagccaacg
     6301 gttaaggtat tcaaccagat gggctttgaa tacggaaccc ttgggaatca cgaattcgat
     6361 gagggcttag ctgaattcaa ccgtatcatg acaggcactg cacctgctga agactcagct
     6421 atcaacgaca ttactaagca atacgagcat gaagcttcaa atcaaaccct tgtcattgca
     6481 aatgtcgttg acaaggagac caacacgatt ccttttggct ggaagcctta tgctgtcaaa
     6541 gaagtcccag ttaatgataa gtcagtcaag gtgggcttta tcggtgttgt gacaacagaa
     6601 attccaaacc ttgtcctaaa acaaaattat gaacaatatg attacctaga ctctgcagaa
     6661 accatcgtta aatatgctaa agagctccaa gagcagcagg tcaatgcgat tgttgtccta
     6721 gctcatatcc cagcaacaag tgataacggg gtagttcatg atgagatggc agcagttatg
     6781 gaaaaggtta accagcttta tcctgagcat agtgtggata ttgtctttgc tggtcacaac
     6841 caccaataca ccaacggtac cattggcaca acacgtgtcg ttcaggctgt ttcacagggg
     6901 aaagcctatg cagatgttcg tggaacacta gacactgacc tcaatgattt tgtagccact
     6961 cctgaagcaa aggtcattgc cgttgctcct ggcataaaaa caggcaatgc cgacattcaa
     7021 gccattgttg atcaagccaa tgacattgtc aaaaccgtta ccgagctaaa gatcggtaca
     7081 gcagctacct cttcaacgat ttctaaaaca gaaaacgaag acaaggaatc tcctgttggc
     7141 aatttgataa caactgccca attaaccatt ggtagaaaaa ccttccctca tgttgatttt
     7201 gccatgacaa ataatggcgg tattcgcgct gacttggtgg tcaaagagga tcaaaccatt
     7261 acctggggag ctgcacaggc tgttcaacca tttggcaata ttcttcaggt cgttcaaatg
     7321 actggccaac aaatctatga tgtcttgaac caacaatacg atgaagacca aaaatacttc
     7381 cttcaaatgt ctggactcaa atacacttat acagctaatg aggctaacga tccttcaaca
     7441 ccgtttaagg tagtaaaggc ttataaagat aatggtgaag aaattgatcc agcagctcaa
     7501 tacaccctaa tcatcaacga cttcctatat ggcggtggtg atggcttctc cgtctttaag
     7561 gacgctaagc tactaggagc cattaatcct gatactgagg tctttatcga atacatcaag
     7621 gaccttgaag cagctggaaa gactgtaagt gctggtatta acggtgtgaa aacctatgtc
     7681 actgccagtc ttgaaggctc tactcaaagt gatcataccg gcaagcacga gatcatcaac
     7741 cgcgtcttta agaatcgtga gggcaaggtg cttgctactg agcttgtctc tgacctattt
     7801 acgcctgctc aaaatgctaa tcctgccaca agcatcaagc ctctagcagc taaaaagcaa
     7861 gctaatgctg ccttaccagc aacaggaaca agccagcatt ctgctgctgc catgacaatc
     7921 ctaggactac taaccttaac tggtactagc cttttcaaga aaaaggaagg ccaataaaat
     7981 cgtcctagcc ataacagcaa taaccgactg tatcttaagc atacagccgg ttttctgatt
     8041 tatgtgacgt ttatttgttt cgcacctgtt gagcaagaca aataaaccac ccatctatgg
     8101 actgccctca ttcgttagat tttctgtcta acttttgggg tgcagttcac taacgggtgg
     8161 tcatgattta aatcaatatg ccctccagat gatccagctc atgctggcag atttgtgcag
     8221 gcaggcctgt caatctcagg gatttcttgt gccaatgtgc atcaaggtaa tcaaccttga
     8281 tctcctgata acgctttgtc ttacgttggc cgattagtga taggcaggat tcctctgcct
     8341 caaacgcttc acgcttagca attaatacag gattaaacat caccaaatcc acaaagccca
     8401 tgctaataat aataaccctc ttgttttccc ctatcatatt agcagccagc cccaggcagc
     8461 tatcacgata ataagctaag gtatcctgca ggtcttgacc aatccaaagg tcctttttcg
     8521 ttgctggctg tgctttttgc tgcaagaaaa aggtgtcctt cacgattttt ttgatcatca
     8581 gcttctcctt gattcattgc tctaatcggc atgcattgtc tagatgaccg atcgtatatc
     8641 ttaacgtcat tgagctaaga ttaatgtgct aaccctactg atatattcag catataccag
     8701 ccacagctct taaacgattc cctgtgctga catggcctga gcaactttga gaaagcctgc
     8761 aatattagct cccaccacta ggttgccttc ttgaccacat tccttggcgg cagcggctgc
     8821 tttttgataa atagccttca tgatgtcata caatcgatga tccacctctt caaaggtcca
     8881 tgcggtacgt ccgctatttt gtgccatttc cagcgcagaa actgctacac cgccagcatt
     8941 tgctgcttta gcaggtccaa aaagaacccc agcctgctga aattgctcaa tagcctctaa
     9001 ggttgagggc atgttagccc cttcgacaac agctttaacc ccatgctcaa tcaaggcttt
     9061 agcatctgcc tcttgtagct cattttgagt cgcacatgga aaggcaaggt ctgccttaat
     9121 agtccagatg gatccctcac cagccggtgt aaacacagca gccgggtgac tctctagata
     9181 ggtcttgata cgctcacgct tcacttcctt gatttgcttt agggtctcaa gatcaatgcc
     9241 cttatcatca taaacgtaac cagaggaatc cgacactgct aataccttaa cacctaaggc
     9301 ctgcaatttt tccgttgcgt aaatggcaac atttcctgat ccagatacaa tagctgtttt
     9361 accagccaag tcctgcccct tagccgccag catttgctga gcaaaataaa ccacaccata
     9421 gcctgtggcc tctgtgcgag ccaaagagcc accataagct aagccttttc ctgtcaacac
     9481 accattctta aagccattaa gacgcttata ttgcccaaat aaatagccaa tttcgcgagc
     9541 ccctacacca atatcaccag caggaacatc aaggtcaggt ccaatatgcc tttgcagctc
     9601 tgtcataaag ctttgtgtga agcgcatgat ttctaggtct gatttgcctt taggatcaaa
     9661 atttgatcct ccttttcctc ctccaatagg ctgaccagtc agagcatttt tgaaaatctg
     9721 ctcaaagcca agaaatttaa ctatagactg gttaacagaa gggtgaaagc gaagccctcc
     9781 cttatatgga ccgatagctg atgaaaattg cacgcggtag ccacgattaa cttggaccct
     9841 gccctggtca tcaacccaag gcaccctaaa ggaaatcaca cgctcaggct caaccaagcg
     9901 ctctaataga ttttcctcaa tataattagg gtatttttca aaaacaggaa tcaaggaatc
     9961 aaatacctcc ttgaccgcct gaagaaattc agtctcatgc ggattatccc ttttgacctt
    10021 atcaaaaaca ctggctacat agtcttttgc tgataccatt atatatcctc tcgcttcttc
    10081 attctatttt aagtatagtc aatattataa attttctgaa ttttgatgtc aagcttttac
    10141 tatgatctaa agcaaattaa aagagccttg gaacgattca ttccaagacc ctaagctttt
    10201 taagactgac tggtcttaaa ttggctatga taaagctcat aatagaagcc cttagcagct
    10261 aataggctgt catgattccc ctgctcgata atctgaccat cttttagaac taaaatctta
    10321 tccgcctctt gaatggttga taagcggtga gcaataacaa agctagtcct gccaaccatt
    10381 aatcgcttca tcgccttttg aatcaaaagc tctaaacgtg tatcaacaga cgaggtggcc
    10441 tcatctagga ttagcagctt tggatctgct aagagagctc gagcaatggt cagcagctgc
    10501 ttttgcccca gggaaatatt gctagattcc tgattcatca ccatatgata gccacctggc
    10561 aatgtcctaa tgaaatgatc aacattggca gccttagcag cctcaattat ttgttcatca
    10621 gtcgcctcta aatgaccaaa gcgcaagttt tcctgaatgc tgccctcaaa gagccaagcg
    10681 tcctgcagca ccataccaaa ctgacgccta taggcttgac gtgacaactg acgaatgtcc
    10741 tgaccatcaa ctgtgataga gccctcattc acatcataaa accgcattaa taaattaatc
    10801 agggtggtct tgccggctcc tgtcggacca acgatagcta ccatctcacc aggcttaacc
    10861 tctaaattga aatttctaat cagaggattg tctgctgtat agctaaaatc aacctgatta
    10921 aaggacacct gacctgttaa atcatgttct aaatgctctt gggcaatagt caattcatct
    10981 gcctcatcaa gcactgcaaa gatacgttct aaggatgact tggcactttg cagtggacca
    11041 gccagctgtg ttatggtctg aataggctga ctgatttgcc aaatgtactg aacaaaggct
    11101 tgcatgtttg ttcccgattg tcaggcggcc tgctatcacc tgtaagccag cgattaaggc
    11161 aacaatcatg taaacagaat ctgaaataaa atgcagaact ggcatcatga tcccagaaat
    11221 aaagctggcc ttaaagccta cttcttgtaa tcgctcagtg atctggtgaa attcctcctt
    11281 tgaggcttct tcacgaccat acagttttaa aatattaaag ccggtcaaat tttcctgcac
    11341 aaagccattc atttctccca aaatattagc ctgcgcttta aaataaggct gtgatttttt
    11401 taaaacaaat cgagaagcag catatatcaa cgggatagcg ataatcacaa cagaggctag
    11461 gggggcatta atatacaaga ccatgccaac caccaaaata agggtaaaaa aggcgttaac
    11521 aatctgtaaa aaggactgct gtaaggcatt agagactgtc tcaacatcag aggtaaaccg
    11581 gcctagcata tcgccgaact gatgcttatc aaaataagac acagggatac gattaatttt
    11641 ttgactgagg tctcgacgaa gatcacaaat gcttgattgc acagcccttg tcataaaata
    11701 gtttgaacca taagagccta actcgtaaac aagggcccta atgatataga gagctaaaag
    11761 aaaggcgata taggttttat taatgcctgc accagagact ccctttgcta tgtctaatag
    11821 gtttgcagat agctctgtta tcaccaagcc aagaacaaag ggctctaaga cactcatcac
    11881 agcactgact atttttaaaa taatggcagt tattagtgag agcctatagg cactaaggta
    11941 ggtccaaatt cttctaaaca catgcttttc agtcattaat ccccctcctc ttttgtcatg
    12001 tcttccttgt ttagctgaga attggcaatt tcacgataga tggcattgct tgtaagcaat
    12061 tcctcatgtg tacctcggcc aacaatttct ccctgatcca agacaatgat ttgatcagca
    12121 tccataatcg tgcccaccct ttgagccaca attaagaccg ttgcatcttg tgtcacctct
    12181 ttcagccgtc tgcgtaattc agcatctgtc ttgtaatcta gggcagaaaa ggaatcgtca
    12241 aagatataga tgtctggctg cttgaccact gctctggcaa tagacaggcg ctgcttttgc
    12301 cctcctgata gattactgcc ggcctcagct agatgggttt gatagccctt ttcacgactg
    12361 gtaataaagt ccttcgcttg ggaaacctct gttgcctgct caagctcact gtggctggca
    12421 tctgacttac catattttag gttttcctca atggttcctg taaatagcag ggctttttga
    12481 ggaataaagc cgattttaga acgcagcgct tttaattgat aatccctgac atcaatgcca
    12541 tcaaccaaga ttctccctaa ggtcacgtca taaaatcgtg ggatcagatt aaccaaagat
    12601 gattttcctg aacctgtcga gccgataaaa gcaatggtct ctccaggcct agtcttaaat
    12661 gagatgttat gtaaaactgg actttccgtt tcacccggat aggcaaaggt cacgttatca
    12721 aattctagat aaccacgtgt tgtgaacgct gttataccat cttcattttt agaaatcgaa
    12781 atcggcatat ccagcacttc cttgatacgc ttgcttgaca ctgctgtttt agggtacatg
    12841 gtaaagaggt tggcaaacat taaaaatgaa aaaagagcat gaaagctata ttcgataaag
    12901 gccaccaaat caccaatctt aaactgcccc cttgccaagg gatccaaggc aaaccagacg
    12961 atccccacaa tcatagcaat gataatttgc acaaataagg gctctgttaa gcctgtcaag
    13021 gtaaatagtc gctttgagat tccagaatag tgatcattgc gcttattgaa gcgctcttct
    13081 tgaaagtctt ctcttgcaaa ggctcgaata actctcagac ctgtcaggtt ttcacgcacc
    13141 aattggttaa tacgatcaag gctctcctgc tgcttttctg ataagggtct tgtctttatc
    13201 gcaacataaa gcaccacaat aactaaaaaa ggcatggcaa cagccacaat ccaagccaat
    13261 gatggactgg ttaaaaagat catcaccact gaaaagatca tcatcaaagg agttacgaca
    13321 cccagcctca aggacatttc agcaaattgc atcaaaacaa aggcatcatt tgttatccga
    13381 gtaaccaggg aggctatgcc aattttttca tattccgaat gcgaataatc ctgcaagcag
    13441 ctatacatgt cattacgtaa atccttgatc atgttggtgg ttagcttacc cgaagcatag
    13501 gataaaatca cccgtccaat gacacctaaa agtacgataa taaacatcat cagagcccaa
    13561 aaataaagag ccctttgatc ctgctgcata acgccttgat caatcatacg agccaatatt
    13621 gttggtagcc ccagattgac cagaacaaat aacaagccac ccacaatatc gaaacaaatc
    13681 catttaggtc ttgtttttaa ataggaccaa attaaagcca ttcatttcct cccaaataat
    13741 agtgatatga aaagaagcgc aagctagcac ttctttttgt ctataactag tttaacacaa
    13801 aaatatgaaa ttgacacata attaattatt cttctaattc gcttaggtaa tcaaagcgct
    13861 cataggcttc aagcagctca agattccgct gatccagctc cttttgatat tgtgccaatt
    13921 ggtcgtaatc acttgccgct ctgagcattt gctcctcaat agtagctatt tgttgctcga
    13981 tagcagctag cttttcttca atagctgccc attccttttt ctcaagatag gacattctct
    14041 ttttagaggt gacctgatgg tcagtgccag ctttttgctc actgacagca ggctctatga
    14101 cctctgcttc aaaagccttt tcatctaaat agtcgctata gttaccatag tattctctga
    14161 tagctccatg ctcaaaagcc aatacttttg ttgcaacctt atccaagaaa taccgatcat
    14221 gactcactgt aatgaccgga ccagcaaatt gagctaaaaa atgctccaac actgtcaagg
    14281 ttgcaatatc caaatcattg gtcggctcat ccagcagcag gacgttgggc ttttcgatca
    14341 agagctttag caaatacagt cttttttctc cccgcctgat agcttagcga ttaaggagcc
    14401 atgactagaa cgcggaaaaa gaaattgctc caaaagctca ctgatgctag tggtgccaac
    14461 actggtcttg acctcatctg ccacctcctg caaatagcta atcacgcgct tgctgccgtc
    14521 catatccttg atttgctgtg aaaaataacc aatacggatc gtctcgccaa tctctagctg
    14581 accagctgtt ggttttaagt caccagtcat caagctaagc agggtggtct ttccagcacc
    14641 gttagctcca acaatgccga tacggtcctt attttgaatg atcaggttaa aatgctcaat
    14701 aatggcctga tcaccataag caaaggaaac ctccttgaaa ttaatgacct tcttgccaat
    14761 acgactggct tcaaaggcca tatctaattg atctataggc ctttcctgat gaaggtcctt
    14821 ttttaactgt tcaaagcggt taattctggc ctgctgcttg gtcgcacgcg cctgtggctg
    14881 tgtcctcatc caagccagct cctgtttata gagctgcttt ttcttatgca aatgagctgc
    14941 ttcgcgctcg tcttgctcag ccttcagacg cacataatcc tggtaattgc cctgatattc
    15001 agtcacatga gccttatcca attcaaagat acgtgtggct atactatcca aaaaatagcg
    15061 atcatgtgta ataaatagaa cagtcctttt agaggtcctt aagtaatgac ttaaccaagc
    15121 gatggtatca atatccaaat gattggtcgg ctcatctagc agcaacaaat cactggctcc
    15181 aagcaagacc tgagccagct gtacccgacg tctcatacca ccggacaggt cacccactct
    15241 ctgatccaga ttgacaatac caagctttga taagaccgtc ttaacctcac tttcgatcga
    15301 ccaaacatct aatcgatcca tctcagtcat cacctctgct agcttttcct gattgctatc
    15361 tgaatagtca gccatcaaca gctcatattg gcgaatcagc tgcatttcct ttaattctag
    15421 ggacagaaca gtatctaaaa cagactgatc atcatcaaag tccggctcct gtgttaaata
    15481 agatatacga tagtcatttg cctttgaaaa aggtgagcgg tcaccatcaa agcccacttt
    15541 ttcagaaata acatcaagca aggttgtttt tcctgtccca ttgacaccaa taatgccaat
    15601 gcgatcacca gcatgaataa taaaggaaat atcctgaaaa acggtcttat ctccaacaga
    15661 cttcgtcaga tgttcaacga taaaatcact catttagtag ttcccttcta acaaaagcct
    15721 caatgtgttc tctttgattg acgagacgcc cctctacaat ggcctgctca atctgattta
    15781 aaagcattcc cagctgtggt cctggcttca ttccaagctc acgaatcaga taagagccat
    15841 tgaccacaat atcatgctta tcatggatcg tcagctcctg atacaagctc tcaacacgct
    15901 tggcctcact gaccaagccc tgtgcctgtc gtaaatcgtc aacgagtaaa gccaagtcct
    15961 tgccaaacga gtaaatatcc catttttcta gctgtctttc ttggcgaatc tgataaagag
    16021 aggccatcat cgtaacccta cgctgaaaat cattagaggt tttccaagcc tttaaaaagg
    16081 ctttaggctg atcaagctcc agcataacca gcaaataggc ccaagcctga tgattgtcct
    16141 gaaacacata atccgctgct aaggttttca ggtacttttg cagggcttct tccttgccca
    16201 ctaagcctgg caaatagtta aaggcctgac atgccaccat agctaagata cctttacgcc
    16261 attttggggc cattaaaagc ttatcaagct caataaaaga gcgctcaata gaaatcttct
    16321 ccagcaaggg agcatggctt ttcattgctt caaaggtctc agcctcaata tcaaaatcta
    16381 agctggcagc aaaccgaaag cctcgcataa tccgcagggc atcctcctca aagcgctcct
    16441 gaggccttcc aacagctctt agaagcttat gctttaggtc ctctaagcca ttaaagatat
    16501 caataacctg tccgtcctca tctaaggcaa gagcattgac agtaaaatcc cttcgtttta
    16561 aatcctcttc caaggaccga acaaaggata cctgactagg gcgcctataa tccacataaa
    16621 cgtcctcagt tcgaaacgtt gtgatctcat attcactgcc attttctaaa acaagcactg
    16681 tgccatgctc aatcccaaca tcaattgttc ttaagaaaat agcctttgtc tcctctggat
    16741 agcagctagc agctatatca acatcatgaa taggcctgtt taataagcta tccctcacac
    16801 ttccaccaac aaaataggcc tcaaagccag cctgcttgat ttttttcact attggtaaag
    16861 ccttctgaaa ttcagaaggc attgtcatta atgttatcat gttttaatct accacctaaa
    16921 agctcctaga gccttgtcat atgcttcccg ttaaaggctg tcatatcaag ctcagattgg
    16981 tcatgggcaa gcctctttag acaagaggcg ttatgccaaa ggcaacagct ccttctccaa
    17041 gatgggctgc aatcactgca ccaaaatgaa cctcctcaac agggcaggta tagccattat
    17101 ccaacaagag ctgctttaag atatcagcct tatcctgcgc tctagcatgg ataattgata
    17161 cctcgtactg accactagct gtcaattcct ttaagatatc aaccaagcgc ttcatggcct
    17221 ttttttccgt tctaaccttt tcatagacga caatctttcc ttcactatca aagcgaagaa
    17281 ttggcttgat gctgagcaaa tttcccagca aagcagaacc gtttgataag cgtcctccct
    17341 tgaccaaatg attcaaatca tcaaccatga taaaggctgt ggttccagcg atttgctctt
    17401 ctagcttatc cataatctct gcaaagctca agccttgctg agaccactct aaagcatttc
    17461 taaccatgct gcctaatggt gctgaggtga ttttactatc tggaaaagca atggtcaact
    17521 cagggtgctc ctcgatgaga aattgaatat tttgccaaaa tcctgaaata ccactagcca
    17581 agaacaagcc aatcacatga gtatagtgct cagttgacag acgccctagt aaatcatcta
    17641 attcagagag gctgggctga ctggtttttg gcagctcttg agattctctc atgctttggt
    17701 aaaaggcttc aatggtcagg ttttgtcctt cgacatagct ttgaccatct atgattacag
    17761 gtatgtctaa tacaaaaata tcggcatgct ccgctaactg ctctggaagg tgagctgtat
    17821 tatcagttat tattgctaac ttcattaact tttaaactcc aaattaatac caggacgatc
    17881 caaggcaatt tctgtcactt cgtaggtcaa gcgcttcacc atgtctaata atggagcagc
    17941 caaggattcg acctcctctt gtgtaaattc actaggctta tccaccaagc gtcctaaaat
    18001 acgaaccatc tgtgaaatca caccactaat cacaaactct tccttgacaa tgacaaattg
    18061 taaaacagaa acaatagccg tctctttatt ttccacatct ttattaatca actgaaaggt
    18121 tacttcaaag tttgtttccg gtgttccatt ttctttttcc cattctaaat ttctggcgtc
    18181 ataatggtac tgattgacaa attctttttc acgtactaat tgcatgattt cgttctcctt
    18241 aatggcgata tgacccatta tagcatagat ttgacgaata ttaaagtaga cttaaaccag
    18301 tattttggat aatttttttc cagaccttgt cacttcaata aatataaacc tgccttctat
    18361 caaccaatca atctcctaca acaaaaaaac accccaaggt gtactgcccc caaaaagttg
    18421 aacgaataat tattgaaagg atttagttct gtattgaaca gggctaagtc cttttagttt
    18481 agttttgatt cgtttattgt tgtagtaaaa gatgtattca gtgattgctt gttcgagctc
    18541 atccagtgag tggtaggatt tctcaaagcc atagaacatc tctgacttta aaatgccaaa
    18601 gaaggattcc atcatcccat t
//
LOCUS       DARYMD010000038        18238 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYMD010000038 DARYMD010000000
VERSION     DARYMD010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18238
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            62..298
                     /locus_tag="TU818_001384"
     CDS             62..298
                     /locus_tag="TU818_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL0924193.1"
                     /translation="MEVIRTLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            362..1633
                     /gene="murA"
                     /locus_tag="TU818_001385"
     CDS             362..1633
                     /gene="murA"
                     /locus_tag="TU818_001385"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL0924194.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKAERLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            1637..1825
                     /locus_tag="TU818_001386"
     CDS             1637..1825
                     /locus_tag="TU818_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL0924195.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLMIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            1857..2735
                     /locus_tag="TU818_001387"
     CDS             1857..2735
                     /locus_tag="TU818_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0924196.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKMVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRKALDSNKRVRYRVTLLYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVASSQP"
     gene            2749..2907
                     /locus_tag="TU818_001388"
     CDS             2749..2907
                     /locus_tag="TU818_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924197.1"
                     /translation="MAKADHVASHHGREALVLVVPQRKVLTIFGLVALVEKQIGPLVE
                     APSMPAPD"
     gene            3647..4690
                     /gene="pheS"
                     /locus_tag="TU818_001389"
     CDS             3647..4690
                     /gene="pheS"
                     /locus_tag="TU818_001389"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL0924198.1"
                     /translation="MDLQAQLEELKTKTQEALKQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            4880..7285
                     /locus_tag="TU818_001390"
     CDS             4880..7285
                     /locus_tag="TU818_001390"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL0924199.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHIVSCDAVPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVETVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKSTEITASS
                     KTVVLEAAVFNGKSIRKTSSRLSLRSESSSRFEKGINHDTLVEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSTSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKETLPTELNHFAFAITGLVADKDFQTQAQAVDFYHT
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGAIIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            7520..8596
                     /locus_tag="TU818_001391"
     CDS             7520..8596
                     /locus_tag="TU818_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0924200.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIIKGKLADYPKEEL
                     QQLTIGDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILVAMV
                     VFAVLGTLFSVFTIVRIDPLEAIG"
     gene            8606..9310
                     /locus_tag="TU818_001392"
     CDS             8606..9310
                     /locus_tag="TU818_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924201.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKKTDFAIKAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSKLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKHKQEAKRQQLFEDLGIAKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDNHHIASNAAMTQN"
     gene            9649..10773
                     /locus_tag="TU818_001393"
     CDS             9649..10773
                     /locus_tag="TU818_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL0924202.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEA
                     LDTAKRAYAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDTNKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(10935..11528)
                     /locus_tag="TU818_001394"
                     /pseudo
     CDS             complement(10935..11528)
                     /locus_tag="TU818_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622734.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            11597..13570
                     /locus_tag="TU818_001395"
     CDS             11597..13570
                     /locus_tag="TU818_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL0924203.1"
                     /translation="MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFDITVRNVTQTTAETSGTTTVKVGNRTATITVTK
                     PEAGTGTSSFYYKTGDMQPNDTERVRWFLLINNNKEWVANTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGENALTEFHTTFPNSVITATDNHISVRLDQYDASQNTVNIAYKT
                     KITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANINANGGVDGSRYTSFTVKKIW
                     NDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKITYS
                     VKEVMVPVGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDRENQDGKRPKEITVR
                     LLANDAATDKVATASEQTGWKYTFTNLPKYKDGKQITYTIQEDPVADYTTTIQGFDIT
                     NHHEVALTSLKVIKVWNDKDDYYHKRPKEITILLKADGKVIREHQMTPDQQGKWEYTF
                     DQLPVYQAGKKISYSIEEKQVAGYQAPVYEVDEGLKQVTVTNTLNPSYKLPDTGGQGV
                     KWYLLIGGGFIIVAILVLISLYQKHKRHNMSKP"
     gene            13594..15036
                     /locus_tag="TU818_001396"
     CDS             13594..15036
                     /locus_tag="TU818_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL0924204.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAAAFAKEAGKHLT
                     ATIAGTGTHAITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGL
                     SYNKDAKVYVVNGDTRQDITNSFTVSEDGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            15117..15926
                     /locus_tag="TU818_001397"
     CDS             15117..15926
                     /locus_tag="TU818_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL0924205.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYVSST
                     QALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPTAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            16238..17395
                     /locus_tag="TU818_001398"
     CDS             16238..17395
                     /locus_tag="TU818_001398"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678097.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL0924206.1"
                     /translation="MMKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTGHVSGEVV
                     EVWPNGQNPNGKIEILSQTEHSEHLQKLRDIEDFQAQKQADHVRYTKWLDGVTVDEHE
                     FRKIKEYDTEYYVTPLLSGKGYYDINKDFNQDSDKCAAAVAANMFHYWFDRNRDSINR
                     FLSQSPGENGVIKLENEKTIEVSKFLETYRSDGDYLDKSPFFDLISNSFKGPVWANKL
                     LDAYINGYGYIHKFAKNTPHSKNNNSKFNFFKKVFDGNLLTDIHQIFDYNTFSDKLSE
                     ALYTGKAIGLAYGPGDLRRSLGHIISVWGADLDDQNRVVAIYVTDSDDKKLTIGNERV
                     GLKRYKVSSDDQGRARLTTRDKDNTGGEIRSIETLDMGTQEWADYFNKTEK"
     gene            17481..>18238
                     /locus_tag="TU818_001399"
     CDS             17481..>18238
                     /locus_tag="TU818_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0924207.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVLTSPTLISADDSSP
                     TIIIKSGAGMTIDPQLPKTLLSKPEEKPEETPKLPDERHYGDDVRPEETPKLPDERHY
                     GDDIKPEEMPKLPDERHYGDDIRKPKPEDTPKPPNESGQGNDLKEDLELKKQRRELTE
                     QLRALKTIEEVLEFLRKPIPGFVTDEDWNFLVSFVEKGPENKTFEVDKLKLLEIFSTS
                     QGHRVWLGYLILEEPMPKPEPKPEPEAKPKPMPKP"
BASE COUNT         5657 a         3680 c         4108 g         4793 t
ORIGIN      
        1 taattattcg tccaactttt tgggggcagt acatttgtta gacttttgat ataataaagc
       61 tatggaagta attagaactc ttttaatgtt tttcagccat ttattattta ttggcattag
      121 ttatcagcta ctcattagcc tagttgattg gtcaaaattc attcattacc gaccagagaa
      181 tatgggaagg cttcgcttgc ttgtcctttt tttggcaatt gcctcaggct atttagttag
      241 tcgctttatg ctggaattaa ttcaaatcag tcagtatctg ctgtatgatt tccactagag
      301 taggcagtca ggaagtatga tataatatta gtacgatgac cagtaggaaa tggagaagct
      361 tgtggataaa ataatcatag aaggtgggag cacacgttta gagggagagg taacgatcga
      421 aggcgctaaa aatgccgttc ttcctttact agcagctact atcctcccct caactggaaa
      481 gactgtcttg agaaatgtgc cgattctctc agatgttttt acgatgaact atgttgtgcg
      541 tggcctaaat attgacgtcg actttgatga ggctgccaac cagattacag ttgatgcctc
      601 aggggacatt ttagatgttg ccccgtacga gtatgtcagc caaatgcgcg cctcaattgt
      661 ggttttaggc ccgattttag ctcgtaatgg ccatgccaag gtatcgatgc ctggaggctg
      721 tacgattggc agtaggccga tcgatttgca tttaaagggc ctagaggcta tgggcgctga
      781 gatcacccag cagggtggtg acatcactgc aaaggctgag cgcctaaagg gggcaatgat
      841 ctatatggat ttcccatcag tgggggctac gcaaaatttg atgatggcag cgacccttgc
      901 tgatggtgtg acagtcattg agaatgctgc tcgcgagcct gagattgttg acctagccca
      961 gctgctcaac aaaatggggg ctaaggttcg tggggcaggt accgaaaccc tgaccataac
     1021 gggtgtcacc agtctatgtg gggttgagca tgatgttgtt caggatcgta tcgaagcagg
     1081 tacctttatg attgctgcag caatgacctc cggtaatgtg ctgattagag atgctgtatg
     1141 ggagcataat cggcccttga tttctaagct catggaaatg ggagtgtctg ttgtcgaaga
     1201 ggatgcaggc attagggtgc aggctgatgt gactaaacta aggcctgtca ctgttaaaac
     1261 tcttcctcac ccaggctttc caacagatat gcaggctcag tttacagccc ttatggccat
     1321 tgttaaggga gaatctacga tggtggaaac agtctttgaa aatcgtttcc agcacctaga
     1381 agaaatgcga cgcatgggct tacaatctga ggtattgcgt gatacagcta tgattcatgg
     1441 tggtcacgaa ttacagggag cgcctgtgat gtcaacagac ctgcgagcta gtgcagccct
     1501 catcttaacg ggaatggttg ccaaaggcag gaccactgtg aataaattga accatttaga
     1561 tcgtggctat tatcagtttc atgaaaagct tgccaagcta ggtgccaaca ttcagcgaat
     1621 tagtgaggag tagtcaatga ctaatggttg gagatatgtc ataaatcagc taatgctaat
     1681 catagctatt ggactgctcg gactcttttg tctggcgctg ggactaatga ttggctatag
     1741 ccttatcggt gatggccaaa atcctttagc gattttatcg ccagataagt gggctgagct
     1801 gattcataaa tttacgggaa agtaggcatg gcctgctttt tatgataaga ggaaagatga
     1861 tcaaaaagaa gaaagacatc aggctgctta atgccttttt agcgctcttg cttgttcttg
     1921 gaacaggtta tttggcagga catgatgacc tagcagctga taacccgatc aagcaggtct
     1981 accaaaggat tcttggctct gacacgcagc aagccgggct accaaaggca agccgagact
     2041 gggacactcc ctccaaggcc ttggcagatt cggtcatgac agccaccatc aaacagcaat
     2101 taggtgatgt gattacttgg aatggcactg gtgcctatat cattaaccat aataaaacga
     2161 cgctaaatgc aaaggtagct agtctcccct atgccaataa taaaacaaag atggtacaag
     2221 ggcaaagcgt tcctaccgta gccaatgccc tgctaaccaa gtcaacccga caatatcaga
     2281 agcgcaatga cactggaaat ggctatagct catggaagcc tgctggctgg catcaggttc
     2341 aggggttaaa gggaaggtat agtcacgcag tggatagagg gcatcttcta ggctatgcgc
     2401 ttgttggcgg gctaaaaggc tttgatgcct caatggctaa tcctagtaat atcgctactc
     2461 aaaccgcatg ggctaaccaa gcagctaacg agagatcaac cggacaaaac tattatgaaa
     2521 caaaaattcg caaagcccta gatagcaata agcgtgtccg ctatcgtgta actttgcttt
     2581 atgagggaaa taatctctta gcaagcggca gtcatcttga ggcaaagtca tcagatggta
     2641 gcttagaatt taacgtcttt atccctaatg tacaggctgg attacagatt gattatcaaa
     2701 caggtcagat cactgtagct tcttcccagc cttagtgagg cacatcacat ggcaaaagct
     2761 gatcacgtag ctagccatca tggcagagaa gcattagtcc ttgtagtccc tcaaagaaag
     2821 gtgctaacaa tatttggtct tgtggcttta gtagaaaaac agataggtcc tttagtcgaa
     2881 gcaccaagca tgccagctcc tgattaggac aaatgtcaag gctaagcggt ggtaagttaa
     2941 agtctcacaa aagacaagac tggacttttg gctatagtcc tttatgactg atgccagctg
     3001 ataatggctc aagatgattg aggtttctag caatgcttgt ggctagccta tcgtcttagt
     3061 tagcgctgat tgatgagatg ttgaacagtt cttgactaaa agcatcccta cccttacgcc
     3121 tacgtcctgg ttagtgaaga aataagcatt gtcataaagg catttttttg atacaataaa
     3181 agtaattgaa tagcagtcta tgagactagt actaataggg aagttaatag ggaatggggg
     3241 tcgtgactgg aagccttctt aatgaaacga ttaggaattc actcaatcaa ggacgaggta
     3301 attaaggtct gacttgctca gatgaaaacg gatggtaccg cgtgtcaacg ctccgcttta
     3361 gataggagcc ttgatacgcc ttttttgatg acgtgctgtt actattagct atttaatcac
     3421 aagcaagcac tagccagcca aaagtaagtg atcactataa gcatagaaag ataggagctg
     3481 tagcttatct agaaaagcaa gggtgatcag tcgtccgccc aaaagtcttt cttagctttt
     3541 gtgatgtgac tagctgacct agctgctcac agcttagcct aaaaggccta ttagcacaag
     3601 gactgccagc attaatgcaa tcattttcca aacagaaggg aatatcatgg atttacaagc
     3661 acaattagaa gaactgaaaa ccaagacaca agaagcgctc aagcagctaa atggtgacca
     3721 cagcaaggaa ttacaggagc tgcgggttgc tgtccttggg aaaaaaggaa cgcttaccga
     3781 actgctcaag ggactaaagg atctctcaaa tgacctgcgt cctgttgttg gcaaacaggt
     3841 caatgagctt cgtgactttt tgacccaagc ctttgaagag caggctaagg tggttgaggc
     3901 agcaaagatt caggccaagc tagattctga aagcattgat gtgactttgc caggccgtca
     3961 gatgaagcag ggctatcgac atgtgctcac tcaaatcagt gaagaaattg aggacatttt
     4021 cttgggcatg ggctttcaaa ttgttgatgg ctttgaggtt gaaaaggatt attataattt
     4081 tgaacgcatg aaccttccaa aggatcatcc ggctcgtgat atgcaagaca ccttctatat
     4141 cacagaggat attttgctgc gcacccacac cagtcctgta caggcacgaa cactggacca
     4201 gcatgatttt tcaaaggggc ctctcaagat gatttcacct ggacgtgttt tccgtcgtga
     4261 caccgatgat gccactcatt ctcatcaatt tcaccaaatt gaaggcttag tcgttggtaa
     4321 gtctatttct atgggagact tgaaggggac tcttgagatg atcattaaaa agatgtttgg
     4381 taaggagcgt aagattcgcc tgcgcccatc ctatttccct tttactgagc catctgttga
     4441 ggttgatgtc tcatgcttca aatgtggtgg taaaggctgc aatgtctgca aaaaaacagg
     4501 ctggattgaa attcttggag ctggtatggt gcacccaagc gttttagaaa tgtcaggtgt
     4561 gaatgcgcag gagtattcag gctttgcctt tgggcttggt caagagcgca tcgccatgct
     4621 gcgctatggt atcaacgata ttcgaggctt ctaccaagga gatagtcgct tttctaagca
     4681 gtttaagtaa tagtgatcat atggtcaaaa accaaatcat cagtttgaaa aaagaactga
     4741 cgctcaatct ggagctgttc tttggattag aatcagaaag gaaaaagacg ggtaaagagc
     4801 aaagaagtga ttggctagct tatctcaagc aggtgctagg cagatctctc atcagcgctc
     4861 actactctat tgaaggctta tgttagtatc ttataaatgg ttgaaaaaat tagttgacat
     4921 tgatgtctca ccggccgagc tagctgaaaa aatgtcaaca acaggtatcg aagtagaagg
     4981 catcaccagc ccctctgaag gtttatcaaa gctagttgtt gggcatattg tctcatgtga
     5041 cgctgttcca gaaacgcacc tgcacctttg tcaggtcaac acaggagatg atgagcttcg
     5101 tcaaattgtc tgcggtgcac ctaatgtcaa agcagggatt aatgtgattg ttgcgctgcc
     5161 tggagctcgt attgcagaca attacaagat taaaaagggt aaaatacgcg gtatggagtc
     5221 tcttggcatg atctgctcac ttcaggagct tggcttacca gatgcgatta ttccaaaaga
     5281 tttttcagaa ggtatccaga tcctaccgga aacagcagca gcaggtgata gcattttccc
     5341 ttaccttgat ttagatgaca atatcattga gctttccatc acacctaatc gtgctgatgc
     5401 cttatcaatg cgtggtgttg cccatgaggt ggcagctatc tatggcaagt cagtgtcatt
     5461 tccagaaaag ccccttatcg aatccgctaa agcagcagct gatagtctag aggttgctat
     5521 tgactctgac aaggtgctga cctatgctag tcgtattgtt gaaactgtca ccgtcaagcc
     5581 aagtccgcaa tggctgcaaa atcttctgat gaacgctggc attcgtccaa tcaacaatgt
     5641 tgttgatgtg accaattatg tcttgctgta ttttggtcag ccaatgcatg cctttgatta
     5701 tgataccttt gctgatcata agcttttagc gcgtgatgcg cgtgagggag aaaggcttgt
     5761 cacccttgat ggagaagagc gtgtgctaac cacagatgac attgttatta ccgtagcaga
     5821 ccagccagtg gctctagctg gtattatggg aggcaaatca acagaaatca ccgcctcctc
     5881 aaagacagtg gtgcttgaag cagcagtctt taatggcaaa tcaatccgta aaacaagcag
     5941 tcggctaagt cttcgttcag aaagctcatc acgctttgaa aaagggatta accatgacac
     6001 gcttgtagag gccttagatt ttgcggcagc catgctagaa gagctagccg gtgggactgt
     6061 tttagcaggg cgcttgcagg caggctcact gcctaccaat ccggtagagg tttcaaccag
     6121 ccttgattac gtcaatgtcc gcttgggaac agccttgagc tttactgata ttgaggggat
     6181 ttttgcaagg cttggctttg gtattagcgg aactgctgaa cactttaccg tttcagtgcc
     6241 acgacgccgg tgggatataa caattccggc tgacctagtc gaagaaattg cccgtatcta
     6301 tggctatgat cgattgccaa ccacattacc agaagctgct ggcacagccg cagaattaac
     6361 caaaacacag gcccttcgtc gtcagctgcg tggtcttgca gagggactgg gtttaacaga
     6421 aatcatttcc tatgctctaa caacacctga aaaggccctt gaatttgcaa tgaagccaag
     6481 ccagttaaca gagctgatgt ggccaatgtc agtcgagcgc tctgtccttc gtcaaagcat
     6541 ggtatcaggt atgcttgaca cccttgccta caatgtggca cgtcaacagc ataaccttgc
     6601 cgtttatgag attggtaagg tctttgagca agagggcaat cccaaggaga cattaccaac
     6661 agagcttaat cactttgcct ttgctatcac aggcttagta gcagacaagg attttcagac
     6721 acaagcgcaa gcggttgatt tttaccatac taagggaatc ctagagtgtc tctttgataa
     6781 gctaggactg tctgtggatt atatcccaac aaaggagatg gcgagcatgc acccaggacg
     6841 taccgcacgt attcagctag gagatcaagt gattggcttt gttggtcagg tgcacccaca
     6901 ggctgctaag gcttatcata tcccagagac ctatgttgca gagcttgacc tgactgctat
     6961 agaggcagct ctaccagctc atcatgcctt tgtggaaatc accaaatacc cagctatggt
     7021 aagggatatt gccttattgg ttgatgcctc aaccagtcat caagccattc tttcagcgat
     7081 cacgtctgcc aaggtaaagc gtctaacaga gattaagctc tttgacattt acgcaggagc
     7141 aattattgcg gccggtaaaa aatcaatggc ctatagcctg accttccaaa atccaacaga
     7201 caatctgact gatgaggagg ttgccggcta catggagaaa atcaccaagg ccttggtaga
     7261 aaaggttggt gcagaggtga gataaggacg cttctaatga ctagctacct aaaaaaagct
     7321 catttcaaag gcttagctgc aattgttctg ttgcggctga gctttttttg atgcttagac
     7381 tgtccttatc ctatgctagt tgcagcaagg gtttagagat gattttattt aaattatcag
     7441 tcaaaaatat tttttctaat caaattccta gctttatctg atctcctctg ctatactgtg
     7501 caataagtaa ggagattata tgtttttagc cctaaatgaa ataaaacaag ctaagctcag
     7561 atatggcttg attatgggac tgctctgttt agtagcctat ttgatgttct ttttatccgg
     7621 tttagccttt ggattaatgc aggaaaatcg ctcggcagtt gacagctggc aggcagatac
     7681 agttcttttg tcaaaggacg ctgacgccaa tctcagccta tcctctttaa agaccagtca
     7741 gcttaaggag atcaaggctg atgaggtcac tcccctagcc cagctgaata cagttgcttg
     7801 gtcaacccaa gctccaacag aagaagacaa agaaaaaatc agcttttttg gcattgagag
     7861 agagtccttt ctcaagccta caatcacaaa aggaaggcta tttaagtcag acaaagaggt
     7921 ggtgattgat caaagccttg ctgagaaagg aggctttaag cttggagatc agctgcgggt
     7981 atcggcctct aaccagacct ataccatcgt tggctatacc aagaatgcta gctttaacgt
     8041 gtcacctgtt gcttacctca acctgacagc ctttcagggc ttactgtatg gtcaagaagc
     8101 aggcgcacaa gacccaaatg ttaatgcctt tattatcaaa ggcaagctag ctgactatcc
     8161 caaggaagag cttcagcagc taacgattgg cgacttcatc aacaagctgc cgggctatag
     8221 tgcacagctc ttgacctttg gctttatgat tgggttttta gtgttaatct cagccattat
     8281 cattggtatt tttatgtatg tgctgaccat tcaaaaggca ccaatctttg gtatcatgaa
     8341 ggcacaaggc attgctaatc gtaccattgc aaatgctgtg ctatcacaaa cctttgtcct
     8401 aagccttttg ggcagcagcc ttggcctact aggcacctgg ctaagctcgc ttgtcttacc
     8461 agcaacagtt ccctttcaga gcaattggta cctatatgcg cttattttag ttgctatggt
     8521 agtctttgca gtattaggca ccctcttttc agtctttacg attgttagaa ttgaccctct
     8581 agaggccatt ggttaggaga agaatatgac agtattagca tttaagcagg tcacaaagtc
     8641 ctttaaggac ggtgatcaga ccattgaagc cctgaaaaag acggattttg cgattaaagc
     8701 aggcgagttt gtcgccctta taggtccatc aggctcaggc aaatcaacct ttctgaccat
     8761 tgcaggtggt ctacaaacac caagctcagg acaattttta gtcaatggca aggattacac
     8821 caacctatct gaaaaggaac gatcaaaact acgctttaag gacattggct ttatcctgca
     8881 ggcttctaat ttgattccat ttttaaccgt caaacagcag ctagaattag ttgacaagtt
     8941 gaccaagcac aagcaggaag caaagcgtca gcagctcttt gaggacttgg gaatcgctaa
     9001 gctggctaat aagctgcccc aagatttatc cggtggcgag cgtcagcgtg ttgccattgc
     9061 cagagcccta taccatgatc ctgtgatcat tttagcagat gagccgactg ccagtctgga
     9121 tactgaaaag gcctttgagg tcgttgaact tctagctaaa gaaagcaagg aaaaaaacaa
     9181 ggcaattatc atggtaaccc atgataaccg tatgattgac tattgcgata aggtctatcg
     9241 catgcaggac ggccaattga gtcaagacaa tcatcatata gctagcaatg ccgcaatgac
     9301 tcaaaactaa tcgaatagga aaagctctgc tctagcgata tagcagggct ttttagctgc
     9361 tctaaattat ctcaaaagtt ccttttactg atatttaata ttttctgtat ttttaattta
     9421 tagaaaaata aagaaacatg ctgagagttg atcaaaacac ttactatact tacgatgaca
     9481 agtaacttgc taaagtaatg gttgacatat aattgtaaaa aaacagaaat aaaaaaaaaa
     9541 cggtttaata ttgacctaat tggcaataac gtttacaata aaggtataat tatctgccgt
     9601 tgataattag gagacatcat gtctagataa aaacaaaagg ggaataaaat ggcaaaaaaa
     9661 gaaatgaagt tttaccttcg taaatcagcc tttgggctag cttcagtatc agcagccctc
     9721 ttggttggtg cggcagctgt atcagcagat tctgttgagt cagctgggcc tgtagcagtt
     9781 gctgttacag atagtttaga tagtgaagcc gcagctacaa aggcagaagc tgatctagtt
     9841 gctgcaaaag cagacctagc agcagcagaa gtagcaatca cagctgcaaa agctgaattt
     9901 gacaccgctc aagcagacct agctaccgct gaagctacta tcgcagagct tgagcaaaaa
     9961 attcctgagt tagagaaaaa aattcaagaa gctcaggaaa aactaaacta tgaaaatcga
    10021 ccatcaccta aacgtgtggg cagtgatgat gaagatgaca cagtagctag aaagcttatg
    10081 tcagaaaagg aagctcttaa ggctgagctt caaaagacta aagaagcgct agatacagct
    10141 aaaagagctt atgctggcat cgaagaaaga aaacaagtag cagcaactaa gctagatgca
    10201 gctaacaagg cttttgctgg agttgaagaa aagcatgctc aagcaatggc tgcatttgga
    10261 gcagcattcg cagcatacaa ggaagctgtt aaggctgaat tgaaggcagc aggtgctagc
    10321 gacttctaca ccaagaagat tgactctgcc gacacagttg acggtgttaa gacactcaga
    10381 gaaatgatct tagactcaat tgctaagcca gaggttgaac cagaggctaa gcctgaacct
    10441 aagccagaac caaaacctga gccaaaacct gagccaaaac cagaacctaa gccagaacca
    10501 aaacctgagc ctaagccaga gccaaaacca gaacctaagc ctgagcctaa gccagaacca
    10561 aaaccagaac ctaagccaaa acctcaacct aaaccagctc cagctccaaa acctgaagct
    10621 aagaaggaag agaagaaagc agcgcctaag caagacacca acaaattgcc atcaacaggt
    10681 gaagctacaa atccattctt caccgcggca gctcttgcag ttatggcagg tgcaggcgtg
    10741 gctgcagtgt caacaagacg caaagaaaac taagccttat accccagtgg taaagcttga
    10801 gcgagaacaa tttgttctcg cttttttagt gtcttaaaag cacctacagc aatcataggt
    10861 gcttaacaag atatgtctaa cgattgctat cagctgtaga gaataaaaag gagagactaa
    10921 gccttgctca caagctactt agaccgaagg agctttagga tttctatgat ttgctgaggg
    10981 gagtccttac agccgcagct gatccactta atgatgatga cctcaataga ggcaatgtat
    11041 agctcaaaaa catatttttg ggtaacttca ggataatctt gtgattctgc acaattcatg
    11101 aggttggaat aggaaataat atccctaata taatgattaa aaattttata aatattagga
    11161 taataaagga ttaagctttg catgacctcc tgattgtcag agaggtagtt taggattttt
    11221 aaggtaatag ttgtatcaag tgatggggat tggtaaatga tagaggtgat atcatctagg
    11281 taaacgccga tcatttccct atctaagtcc ttcttagagt tgaaataatg ttaaaaggtt
    11341 gttcgactga tattagaagc cttgctaata tctgatacag taatactgtc cttatccttg
    11401 tattgtagta gtcggcagta gcttttaatt atttttttac aagtttgttt atttttatcc
    11461 attgtatcat taactcctta aaattgaaca ttaatgttaa ttttgtacat aatatttttt
    11521 gctaacatta tacaatgatg aacgtgattt gtaaaattaa attttgcaaa tcaataatgt
    11581 aaaaggagga ttttgtttga aacaactgac aaagatcgtt agtgtggtct tgttgctggt
    11641 ctttaccctt agtgctagcc tgcacaaggt tcgggcaact aatcttagtg acaacatcac
    11701 atcattgacg gttgcttctt catcactccg agatggagag agaacgacgg taaaggttgc
    11761 gtttgatgac aaaaaacaga aaatcaaggc aggggatacg atagaggtca cctggcctac
    11821 aagtggtaat gtctacattc agggctttaa taaaaccata ccgcttaata ttagaggggt
    11881 agatgttggt accttggagg tcacgctaga caaggctgtt ttcacattca atcaaaatat
    11941 tgaaacaatg catgatgtct ctggttgggg agagtttgat attactgtta gaaatgtgac
    12001 acaaaccacc gctgaaacat caggaacgac cacagtaaag gtaggcaatc gcactgctac
    12061 tatcactgtt actaagcctg aggcaggcac tggtaccagc tcattttatt ataagactgg
    12121 tgatatgcag cccaatgata ctgagcgtgt gagatggttc ctgctgatta acaacaacaa
    12181 ggaatgggtg gccaatactg ttacagtcga agacgatatt caaggtggtc aaaccttgga
    12241 tatgagcagc tttgacatca ccgtatctgg ttatcgtaac gagcgcttcg ttggggaaaa
    12301 cgctctgaca gagtttcata caacatttcc aaattctgtc attacggcaa cagataatca
    12361 cattagtgtg cggttagatc aatatgatgc ctcacaaaac actgtcaaca ttgcttataa
    12421 gacaaagata acggactttg accaaaaaga atttgccaac aacagtaaaa tctggtacca
    12481 gattttatac aaggatcagg tatcgggtca agagtcaaac caccaagtag ccaatatcaa
    12541 tgctaacggc ggggttgatg gcagtcgcta taccagcttt actgtcaaga aaatttggaa
    12601 tgacaaggaa aatcaagacg gtaagcgtcc aaagactatt actgttcagc tttacgccaa
    12661 tgatcagaaa gttaatgata agaccattga attgagtgat actaatagct ggcaagcaag
    12721 ttttggtaag ctggataagt atgacagtca gaaccaaaaa attacctaca gtgtcaagga
    12781 agtgatggtt cctgttggct accaatcgca ggttgagggg gatagtggag taggatttac
    12841 cattaccaac acctatacac cagaggtcat tagcattacc ggtcaaaaaa cttgggacga
    12901 cagggaaaac caagacggta aacgtcctaa ggagattacg gttcgtttat tggcaaatga
    12961 cgctgcaact gacaaggtag caactgcttc agagcaaacc ggctggaagt atacatttac
    13021 caatctaccg aaatacaaag atggtaaaca gatcacctac acgatccaag aggaccctgt
    13081 ggcagattac accacaacca ttcagggatt tgatattacc aatcatcatg aggtagcctt
    13141 gaccagccta aaggtcatca aggtttggaa tgataaggac gattattacc ataaacgtcc
    13201 caaggagatt accattttgc taaaggcaga tggcaaggtg attcgtgaac atcagatgac
    13261 accggatcag caaggaaaat gggaatacac ctttgaccag ctgccggtct atcaggcagg
    13321 caagaaaatc agctacagca ttgaggaaaa acaggttgct ggctatcaag cccctgtcta
    13381 tgaggttgat gaaggcttga agcaggtcac tgtaaccaac acccttaacc caagctacaa
    13441 gctgcctgac accggaggac aaggagtgaa atggtacctg ttaatcggtg gcggttttat
    13501 catcgtcgca atccttgtac tgatcagcct ttatcaaaaa cacaagcgcc ataacatgtc
    13561 aaaaccataa catgtaatag aggagagaga gctatgaaaa caatcaaatt aatcttgacg
    13621 agcttgcttg tcaccttcct aacaatgctg tcaggaaagg catttgctga tacagcaagc
    13681 tataccatca ctgttgaggg agctacagca ggtcacacct atgaggctta tcagattttc
    13741 aagggtgact tgtttgacag taccctatca aacatcacat ggggaggtgg tgttacacct
    13801 tttgaatttg atggttcaaa agacgctgct aagattgcag agggattgaa ggaagcaaat
    13861 gcagctgcct ttgccaagga agcaggtaag cacttgacag caaccattgc aggaacagga
    13921 acacatgcaa tcaccgttaa cgaggctggc tactacctca tcaaggacaa aaatgattct
    13981 caaacaggca agcatgacgc ctacacctca tttgtcctga aggttgttaa aaacaccagc
    14041 ttcaaaccaa aatctgctat cccaacagtc cttaaaaagg tcaaggaccg taatgacaag
    14101 acaggtcttg agacaggctg gcaagattca gctgactatg acaaaaatga caaggtgcca
    14161 ttccagctaa ccgcaaccct accgtcaaat tacgatgcct ttcaagaata ctaccttgaa
    14221 tttgtagata ccttatcaaa agggctaagc tacaacaaag acgccaaggt ctatgtggtt
    14281 aatggagata ctcgtcaaga tattactaat tcatttacag ttagtgaaga tggttcatct
    14341 tttaaaatca ataacctaaa ggctgttcag ggagtaacaa taacagctac cagtaagatc
    14401 gttgtcgaat acactgctac cctcaatgac caagcggcca tcggcaaaaa aggaaatcca
    14461 aacgaagttg ctttgaaata ctcaaacgat ccaaacgctc ttggaaaagg agaggagtct
    14521 ccaaaagggg agacaccaaa agacaaggtt atcgttttca cctataaaac tatcatcaat
    14581 aaggttgatc aagatcaaaa agccctaaaa ggtgcaggct ttacccttta taagctggtc
    14641 aaaggtgata atggcgagga aaaatatcaa atagtccaag aaattaaagc aggggataca
    14701 actagctttg agtttgttgg acttgacgct ggtgattaca agctcagcga aacaacaaca
    14761 cctggcggtt acaacactat tgcagatgtc atgttcagca ttgtagcgca gcatgaaacc
    14821 gagtcagacg atcctcagtt gactagccta accgttgaca aagcaactgg cttcactgct
    14881 gatacagaag ctggtaccgt atccgcaact attgttaata aaaaagggtc tatcctccct
    14941 tcgacaggaa gtatcggaac aaccatgctc tatgtgtttg gagtaatgct aatgacaata
    15001 tcaacgctgt ttatctttcg tcagaaacag caataagatc gtgtgagtag gtaaaaagaa
    15061 gtggatagac gtcttaccaa gacctattca cctctttttt tgatagaggc tatagaatga
    15121 agaaaagtgt cattttttgg agtgtgattt tggtggcagg ctgtctgatt gtcctttacc
    15181 ccacccttag taactattgg aatgcacagc accaatcaca gctcatcgct gactatgtct
    15241 caagcacgca agctttgaga cataaggata gtcagctcat gctagaagca gccaatcagt
    15301 acaatcagca gctaaaagct aaccatgatc ctgatttaac cttgaccgat agtgaggcag
    15361 aagcctatca gcagcagctg gatctgacaa atacaggtat catggcctac atagatattc
    15421 caaaggtgca tgagcggctg ccgatttatc atggcaccga tgaggagatc ctacaggtgg
    15481 ctatcggtca tcttgcaggc acctctttgc ctgtaggtgg caagggaaca catgctgtca
    15541 tctcaggaca tcgagggtta ccctctgcca agctatttac caatattgat aagctgagga
    15601 ttaacgatac ctttaccatc accagtctta ataggactat gacctatcag gtggataaga
    15661 ttgctaccgt tttgcctgat gatgtcagcc tcttaaggat agaggagggg aaggatctgg
    15721 taaccttggt cacctgtacc ccctacggtg tcaacacgca tcggctcttg gtcagagggc
    15781 atcgtatcaa aacagcgaca ccaaccgctg caagaggatc tcaaaagcct agtaggctaa
    15841 tcctctggct cttgctaatc agtgcattag ggctatctct cgtactaata ggcacttggc
    15901 gctggcgtag gaggtctaaa gcatgagcag gctttccaga agcaactaag tcaaatcatc
    15961 aacccttgat aggttactga ggacctatca ggggattttt tagtgctaaa ttgcgactat
    16021 gattaaaaac acagaaatcg tttttttttc ttagtgaccg aaaacgcttt aaaagagcga
    16081 gcatttggag ccttcaaaag tgacatctga gcataacatg ataaaattga cttataaaac
    16141 ctaataaaat gataaaagga ggagagttaa cgacaaaata ttagatattt atttaatttg
    16201 ttgtttttga aaacgtttta taataagaaa ggatagcatg atgaaaaaac aatcattcac
    16261 acactcacgt aaacctaaat tcggtatgag aaaattatct attggccttg cctcatgtat
    16321 gctaggaatg atgttcctaa caacaggaca tgtttctggt gaggtagttg aagtttggcc
    16381 taatgggcaa aatcctaatg gtaaaataga aattctaagt caaactgagc actctgagca
    16441 tttacagaaa ttacgcgata ttgaagattt ccaagctcaa aagcaagctg atcatgttcg
    16501 ttacactaaa tggttagatg gggtaactgt tgatgagcat gaattcagaa aaatcaagga
    16561 atatgacaca gaatattatg taacacctct tttaagtggt aaaggttact atgatatcaa
    16621 taaagatttc aatcaagata gtgataaatg tgctgccgct gtagcggcta atatgttcca
    16681 ttattggttt gatagaaata gagacagtat taatcgtttc ttaagtcaaa gtccaggtga
    16741 aaatggtgtt attaaacttg aaaatgaaaa aacaatagaa gtatcaaaat ttttagaaac
    16801 ttaccgtagt gatggtgatt atcttgataa aagtccgttt tttgacctta tcagtaacag
    16861 ctttaaaggt cctgtttggg caaataagct attggatgct tacattaacg gctatggtta
    16921 tatccataaa tttgctaaaa atactccaca ttctaaaaat aataatagta aatttaattt
    16981 ctttaaaaaa gtatttgatg gtaatctctt gacagatatt caccaaattt ttgattataa
    17041 cactttttca gataaattaa gtgaggctct ctatactggt aaagccattg gattggccta
    17101 cggacctgga gacttgcgtc gttcactagg tcatattatt tctgtctggg gagctgatct
    17161 tgacgatcag aatcgcgtgg tagctattta tgtaactgat tctgatgata aaaagttaac
    17221 tataggaaat gagagagttg gtttgaagcg atataaagta tctagcgatg atcaaggtcg
    17281 tgctcgtctg acgactcgtg ataaagataa cacaggtggt gaaattcgat ctattgaaac
    17341 attagatatg ggtacacaag agtgggcaga ttacttcaac aagacagaaa aataacaata
    17401 acccctacac atatatgatt actccagata aagcacacag caatagactc agccagtaag
    17461 gaaaggacga taacaaaacg atgctaacaa accaaacggg gtacaggcat agacttagta
    17521 agcagaagct acctatcagc atggtttcct gcttgctagg aatgggggtg ctaacctctc
    17581 caacattaat ctcagctgat gatagttctc ctactatcat cattaaatcg ggtgcaggta
    17641 tgacaattga tcctcaatta ccgaaaactc tcctttctaa acccgaagag aaaccagagg
    17701 aaacacctaa acttccagat gagcgacatt atggtgatga tgtcagaccg gaagaaacac
    17761 caaagcttcc agacgagaga cattatggtg acgatataaa accggaagag atgccaaagc
    17821 tcccagatga gcgacattat ggtgatgaca tcaggaagcc gaaaccggag gatactccaa
    17881 agccacctaa tgaaagcggt caaggtaatg acttaaaaga agatttggag cttaaaaagc
    17941 aacgtcgaga gcttacagag cagcttcgtg ctttaaaaac tattgaggaa gttttagagt
    18001 tcctgagaaa accaattcct ggatttgtaa cagatgaaga ttggaatttc ttagtatcat
    18061 ttgtagaaaa aggcccagaa aataaaactt ttgaagtaga taaattaaaa ttactagaaa
    18121 tcttctcaac ctcacaaggt catagagttt ggttaggtta ccttattctg gaagagccaa
    18181 tgcctaaacc ggaacctaag ccagagccag aggctaaacc aaaaccaatg cctaagcc
//
LOCUS       DARYMD010000039        17857 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYMD010000039 DARYMD010000000
VERSION     DARYMD010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17857
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(223..1323)
                     /locus_tag="TU818_001400"
     CDS             complement(223..1323)
                     /locus_tag="TU818_001400"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL0924208.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            complement(1320..1676)
                     /locus_tag="TU818_001401"
     CDS             complement(1320..1676)
                     /locus_tag="TU818_001401"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL0924209.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            complement(1792..4320)
                     /gene="secA"
                     /locus_tag="TU818_001402"
     CDS             complement(1792..4320)
                     /gene="secA"
                     /locus_tag="TU818_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL0924210.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            complement(4696..5640)
                     /gene="manA"
                     /locus_tag="TU818_001403"
     CDS             complement(4696..5640)
                     /gene="manA"
                     /locus_tag="TU818_001403"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL0924211.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSTVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            complement(5756..6640)
                     /locus_tag="TU818_001404"
     CDS             complement(5756..6640)
                     /locus_tag="TU818_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL0924212.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLTAAFAIP
                     FYVTTDVNSSAYGEAISRPDVDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYVM
                     QHLDDVANAFLGVCPFHRGCLEGMAAGPSLEARAGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLVRVQEAFTRLINGYLPVADVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            complement(6997..10053)
                     /locus_tag="TU818_001405"
     CDS             complement(6997..10053)
                     /locus_tag="TU818_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL0924213.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKVVQTS
                     PSVSAIDDLHYLSENSKKEFKEGLSKAGEVPEKLKDILSKAQQADKQAKVLAEMKVPE
                     KIAMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSFF
                     WQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDTQKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDIERDSIPKVNGKESNENIQRSIAVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAQYIDLLLVQVYGTQGEKGDWDPVARKPEKTMEEHWESYSK
                     YIRPEQYMVGFSFYEENAGSGNLWYDINERKDDHNPLNSEIAGTRAERYAKWQPKTGG
                     VKGGIFSYAIDRDGVAHQPKKVSDDEKRTNKAIKDITDGIVKSDYKVSKALKKVMEND
                     KSYELIDQKDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPDIKSLEGLNKLKKLA
                     KLELIGLSQITKLDSLVLPANAKPTKDTLANVLEAYDSAKKEETKAIPQVALTISGLT
                     GLKELNLAGFDRDSLAGIDAASLTSLEKVDLSSNKLDLAAGTENRQILDTMLATVTKH
                     GGVSEKTFVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSE
                     ADYKAYQEQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETY
                     KVEFFSPTNSTKPVHEAKVVVGAEKTMMVNLAEGATVIGGDADPTNAKKVFDGLLNND
                     TTILSTSNKASIIFELKEPGLVKYWRFFNDSKISKADCIKEAKLEAFVGHLEAGSKVK
                     DSLEKSSKWVTVSDYSGEDQEFSQPLNNIGAKYWRITVDTKGGLYNWPSLPELQIIGY
                     QLPAADLVMAMLATAEELSQQKDKFSQEQLKELEVKIAALKAALDSKMFNADAINAST
                     ADLKAYVDKLLADRTDQEKVAKAAKVEQPVATDIKENTEPENPKTD"
     gene            complement(10282..12165)
                     /locus_tag="TU818_001406"
     CDS             complement(10282..12165)
                     /locus_tag="TU818_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL0924214.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVAIGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYLVTLLVGLGLAFVIA
                     YIWGFKDKSDQEAPATQVKSEPAQKASAAEELLSPVAGELIDLSSVADPVFSSGSMGQ
                     GVAIKPEGRILCSPVDGRVEAALETGHAYVIKSDKGAEILLHIGIDTVSMAGEGFETF
                     VKVGQMVKAGDALGSFDIARIQQAGLDTTTMLLVTNSADVHAVQILAQGKVTVGSPVI
                     LVK"
     gene            12442..13881
                     /locus_tag="TU818_001407"
     CDS             12442..13881
                     /locus_tag="TU818_001407"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL0924215.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQDQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRRKLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPALSKLRDKAQPFQNKKNSSNCYELALTIEAQQATELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGAKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            13886..14851
                     /locus_tag="TU818_001408"
     CDS             13886..14851
                     /locus_tag="TU818_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0924216.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPHIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKGADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGGSL"
     gene            complement(15228..15733)
                     /locus_tag="TU818_001409"
                     /pseudo
     CDS             complement(15228..15733)
                     /locus_tag="TU818_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15730..17136)
                     /locus_tag="TU818_001410"
                     /pseudo
     CDS             complement(15730..17136)
                     /locus_tag="TU818_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515913.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17127..17486)
                     /locus_tag="TU818_001411"
                     /pseudo
     CDS             complement(17127..17486)
                     /locus_tag="TU818_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17498..17764)
                     /locus_tag="TU818_001412"
     CDS             complement(17498..17764)
                     /locus_tag="TU818_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL0924217.1"
                     /translation="MSDTITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
BASE COUNT         5024 a         4422 c         3375 g         5036 t
ORIGIN      
        1 cattgaagca aaataaaatg caagattttt tgtattaatg ccttaatact cggataaagg
       61 taagggcctt ttcttattct ttttcttaac ccgcagaaaa acaagacctg tcttgatctg
      121 ctctatctat gctgttagcc tgaggtctca agacctttac aggactaatc atttgaaaga
      181 cagccttgag gccagtcaat agttgagcct aggctcaatt tcctaatatt ctctaggaat
      241 acgatcactc agcaagcaaa gcacctcata attaatcgta cctctataat cggcaacatc
      301 ggttgctgtg attacttgtt taccctgctg tccaatcaag gtcaccttag tgccgatagg
      361 ataggcttta ggcaaacgaa tggtcaattg gtccatcgac acacgaccaa taatgtcaca
      421 aaattcccct tctaccaata ccttaaagcc ctgcatattt cgagtccaac cgtcagcata
      481 gccgataggt aaggtcccga catactctgg ttctgctgct acatagctag ctccatagcc
      541 aacgctatcc cctgcctgaa tttgcttcac atgaaccaaa cgtgattcta aggacaaggc
      601 ttcctttaag ggacaaggta gactcaagct attgccgctt ggattgagtc catagataac
      661 aataccaagg cgaatggcat taaaaattgt ttcactatgc caaaggcttg ttgcagagtt
      721 gcttgcatgc actaatgcag gcctcttatc tagctgctcc accaactgct tgaaaaaggt
      781 cagctgctta tcgaacatgg catggtcaga gtcatctgcg gttgcaaaat gcgtgaaaat
      841 cccgtcaagc tgcactccca tatcggataa gattgagatg agctgattgg cctcagcaag
      901 cgacctgaca ccaatgcgcc ccattcccga gtcaaccttg acatgcacat gaagctgact
      961 gaaatcaacc gattcctttt tggcaagctc tagccactct aagctggcca ctgttatcgt
     1021 cagctgatgc ttaatggcta gctgcaattc acttgctaaa atcaccccta aaataaggat
     1081 ttccttatca atgcctgcct gacgtaattc caaggcttca tcaaggtttg atacgcaata
     1141 gccatcaacc tgatcctcaa ctgccttgga cactgcaact gccccatgac cataagcatt
     1201 ggccttgaca acagcatatg tccttacctt tttaggaata tgctgatgaa tatggtcaat
     1261 atttgctcga atagcttcta agtcaactct agctactgtt ggtcgatgta agcttgaaat
     1321 catgctaaat cctccaaaat aacacttgct tgaacatagc ccccactatg tgaaatactg
     1381 ataaaggcct taccctgaaa gggagatttt gtaatgacgg gacgcccttt gctgtcattg
     1441 ataatttcaa tatcctgaaa ggttagctgg ccaatccctg tccccattgc ctttgaaaag
     1501 gcctccttac cagcccagcg gccggccaga taggtcattt ttcggtgatg ggaaaattgc
     1561 tcaaacagcg ctagctcctt gtccgtcaaa acctttctag caaatctagc atttctcaaa
     1621 taaacctttt caatagctga aatatcctgt aaatctatcc catgtccaac aatcatttgc
     1681 ctttatttta ccagccttca ctttaattta gggaaacaaa tcctaaacaa ggagaagccg
     1741 agaacaaatc tcagctcctc acaggttttc aacatggcca tcacgctatc cttaaaaagc
     1801 cttacgacca tgacagtttt taaacttctt accagagtga caaggacaag catcattgcg
     1861 ctcgactctt gaaaaatcag ctgatgaatc aaaatcagca ccgatagcct gcgactgaat
     1921 gttttgtgct gcagttgttg ttgcatactg aattgcacgc tcgcgctcct gctcatgaat
     1981 ctgtgccttc atcatggtac gtgtaacatc aaattcgata gcaccaatca tatcctgaaa
     2041 catcttgaag ccttcacttt gatattcaac aactggatta ttttgcgcat aaccacgcaa
     2101 accaaccgca ttacgaagct ggtctaaggc atcaatatgc tctgtccatt tgttgtcaac
     2161 aatcatcaaa atcagcacct tctggaattc taagatagcg tcctgatcgc gcaattttga
     2221 taactgctta tcgtaaatct caagggcacg ctgatagagc ttgtctttga tctgatcgtc
     2281 cttgaggcca cgcaattcct tagcaccgat ggtttcctct gggacaattg atgttctcgc
     2341 aaaagtcacg atggcgtcaa tagcgtcctt acgattggta cgtgagtggg catcaactgc
     2401 tcgatcaatc gtacgcttga tcattgcctt aatttcagga cctaggtcac gatttgctgt
     2461 gataacatca cgacggttag cgtaaataat ctcacgctgc tcacgcatca catcatcata
     2521 ctgcaagacc tgcttacgtg tgtcatagtt attaccctca acacgttttt gagctgactc
     2581 cacctggcgt gacagcattc tggacttgat aacaatatcc tcgtcatcat tgttcatacg
     2641 atccaagaaa gccttaatac ggtctgtacc aaagcgcctc atcagctcgt cctctaagga
     2701 gaggtagaat tgtgactccc ctggatctcc ctgacgacct gaacgcccac gaagctgatt
     2761 atcaatacgg cggctctcat gacgctctgt cccgataaca caaagcccac cgagctctcg
     2821 gacaccctca ccgagcttaa tgtctgtccc acgaccagcc atattggtcg caatcgttac
     2881 cgcaccacgc tgaccagcat tcataataat ctgtgcttct ttaaagtggt tcttagcatt
     2941 taagacctca tgcggaatgc ctgcttctac tagcttttta gaaatcaggt cactggtctc
     3001 aacagcaact gtaccaacta gaacgggctg ccccttttca tagcgagcct taacatctgc
     3061 aaccactgcc ttgaattttg aattcaacgt tgcataaaga aggtctgtgt gatcaatacg
     3121 agcaatagga cggttggttg gaatcggaat aatacgcatg ttgtaaactt cgcggaattc
     3181 ctcttcctcc gtttttgctg taccagtcat acccgccaat ttcttataca tacggaacat
     3241 gttttggtag gtaatagagg cacttgtttt tgattcctct tgaatacgaa cgccctcttt
     3301 tgcctcaata gcttggtgta agccatccga aaagcgtcgt ccctccattg tacgacctgt
     3361 aaactggtct acaatcaaaa tctcgccttc ctcgctaacc acataatcaa tatccaaaag
     3421 catgatataa ttagcacgaa gggcattatc cacgaagtgg gtcaaggcaa cattttcaat
     3481 atcgtatagg ttgctgaggt tgaaatagct ttctgcctta tcaatacctg agtcgcttag
     3541 gccaatcgtc ttggtcggaa catcaatgat gtaatccact gaatccaagg tcttgacaaa
     3601 catgtctgca cgaatataga gctgattcgt ttctgagctc acagcaccag atacaatcag
     3661 aggtgttctt gcctcgtcaa tcaaaacaga gtcaacctca tcgaccaagg caaagttcag
     3721 tggtcgctga accatgtcct cttgacgaac caccatatta tcacgcaggt agtcaaagcc
     3781 tacctcagag ttggttgagt aggtaatatc acatagataa gcctcacgct tttcagctgg
     3841 tgatttggct gctaggttga taccgactga aagccctagc cagctataca cctctcccat
     3901 ctctgtcgcg tcacgagttg acaagtattc attaacagtg ataacgtgta ccccttcgcc
     3961 agcaagggca ttaaggtaaa caggcatggt cgctgtaagg gtcttacctt caccggtacg
     4021 catctcaggg acatctccat tgtgcaagac aacccccccc atgatctgaa cacgataagg
     4081 gtaaagtccc agcacacgtc tagccgcctc gcggacaacc gcaaatgctt ctggtaataa
     4141 ctgctcaagg gtttccccat tttgataacg ttgtttaaat tcgggcgttt ttgcttgtag
     4201 gtctttatct gacaaggact ccatatagtc agcataggac tctacttttt tcgcaatttt
     4261 ttctaatttt cgtaattcgc ctttatcatt ttcaatgact ttgcgtagaa tattgctcat
     4321 tctctttcct ttcgatcgac taatcatttt attctaacat aaataggcag gcagttcaag
     4381 aaatgatcat aagatatcca tgacagacgc atgaagaaaa tcatttattg aaaaagttgt
     4441 gaaaatagca aaatagccat tttagggtat ttgacagagt gtttcctgaa ttgttatatt
     4501 ctccctctat aaacttttct tgaaaaattt cttttctgca actatcgcta tggctttcct
     4561 atttttcaga ataagttttc gcattcagaa atatcttgga aattttttct tcatgcgtct
     4621 gtcgtgataa gatatcagaa aaagaaaggc cgcttgtcca aacagtcttt cttggtgttt
     4681 tcgtgtattc tgtacttaat taggatgact gacaatcatt tccagctgac catcaaagct
     4741 ccatgacgtc acatcatttg gcaggataaa atgcataccc ttttgaagct cgtaaacagc
     4801 ttgatcaatc gtaaggcttc cctgaccagc tagcacactg acaagcaggt aaggggctga
     4861 ttgcttcatg ctgactgctt gatcaatctc ccatttgtaa actgtaaaga agggattaga
     4921 tactaagcag gtagagacca agtgctcaag ttctagtgtg gctggcgtgc tgttctcagg
     4981 cttgccaata gttaggacat cgatagattt ctcaatatgg agctcacgaa gctgaccttc
     5041 agcgtctcga cgatcaaaat cataaacgcg ataggtcgtg tctgaggatt gctgcgtctc
     5101 taagatcaaa attcccttac caatggcatg catcgtgccg cttggaacat agaagaaatc
     5161 accagcctta accggaactc gcgtcaacaa ctcttcccag ttccccgcct caatcatcgc
     5221 acgaagctct tgtttagagc ttgcatgatg accataaaca atctcagcgc cttcttcagc
     5281 tgaaataata taccagcatt ccgtctttcc tagctctccc tcatgggcca gcccataagc
     5341 atcatctggg tgtacctgaa cgcttagcca gtcattagca tctaaaatct tcgtcaacag
     5401 cggaaagacc ttttcctttg gatttccaaa tagctctggt ctttctgcat aaagctgatc
     5461 tagcctttgg ccttggtagc taccactgct aactgtggaa acaccattag ggtgagctga
     5521 gattgcccaa tactccccag tggtttcggt tggaagctca tacccaaaca cctctcttag
     5581 ctttgttccg ccccagatct tatcatgcat gcatgatgtt aaaaataatg gttctgacat
     5641 agtaatcctc attctctttt cactaaccta tggtgacatt ctttgcccca attctaccaa
     5701 tttcaggcac attttgcaaa tgactctagg acttttatca aataggctca agtatctagc
     5761 tcttttcagc aatcagcttt gctaaagcaa aattcccaag agtggccgag ccattacctg
     5821 caactgctgg tgtgaccaaa tattctctaa catcagctac tggtaaataa ccattaatca
     5881 gtctggtaaa ggcctcctga acacgcacca gcatgtgctc ctgtgccatc acacctccac
     5941 caaacacaat aacctgagga cgataaagca gcgttgcctg tacagcagcc tgagctatat
     6001 agaaggcttg aatatcccaa acagcggcct tctgatcaag aagctccccc ttaatccctg
     6061 cccttgcttc aaggcttggc cctgctgcca tgccctctaa gcacccccga tgaaatggac
     6121 aaacacccaa aaatgcattc gccacatcgt caaggtgctg cataacatag gtatgtcccg
     6181 cctctgtatg acctaaccca ccgataaact cacctttttg aatagctcca gcaccaatac
     6241 ctgttccaat cgtataataa acaagactgt caacatcagg tcgagagata gcctccccat
     6301 aggcagaact attaacatca gtcgtcacat aaaaaggaat cgcaaaggct gctgtcagct
     6361 gccctaatag atctacattt gcccaacctg gcttgggtgt tgtggtaatg tagccatagg
     6421 tagctgactt aggatcaata tcaatcggtc caaaggagcc aatagcaata ctagccaagt
     6481 cggcctcaaa ttgcttaaaa taagcaatcg tacgctcaat agtctctttt ggacttgtcg
     6541 ttggaaattg caccttatcc acaacagcaa aatccctatc accaacagca cagacaaact
     6601 ttgtcccgcc tgcttcaata cttccaagta atgttttcat cttttctcct taataatagt
     6661 gataagccct gtgctggtta ttctcacaag gctcaaaatc ccaccagcta atcagcagct
     6721 accttagtag ctaaacatca tcgcttgctt ccttgcctcc tagaaaagac caaaaatctg
     6781 ggataggact atctcagatt tttgatatgc ctttaagaga taaggcaatt gattttagga
     6841 gggaaacctt ggcagcagga gctgccacca agaagcagca caaacaattg cttttaatgg
     6901 tgtgttcatc gccttatctc taaagcttaa tgtgttagcg taatgatcag taacctcaag
     6961 ctaacggcca agaacgacag cctgctcaag gataagctag tctgtctttg gattttctgg
     7021 ctcagtattt tcttttatgt cagtagccac aggctgctca actttagctg ctttagctac
     7081 tttttcctga tcagttctat cagctaaaag cttatcaaca taagccttca gatcagcagt
     7141 actagcgtta atagcatcgg cattaaacat cttactatct aaagcagcct ttaaggcagc
     7201 tattttgact tcgagctcct taagctgctc ttgagagaac ttgtcttttt gctgagatag
     7261 ctcctctgca gtagctagca ttgccatcac aagatccgca gccggtaatt gataaccaat
     7321 gatttgaagc tcaggaagtg atggccaatt gtaaagtcct cccttagtat caactgttat
     7381 tctccaatat ttggcaccaa tgttgtttaa cggctggcta aactcttggt cctctcctga
     7441 ataatctgaa actgttaccc attttgatga tttttccaag ctatccttta cctttgagcc
     7501 agcttcaaga tggccaacaa aggcttcaag cttggcctcc ttaatacagt cagctttact
     7561 aattttgctg tcattaaaga aacgccaata cttgactaag ccaggctctt taagttcaaa
     7621 aatgatagaa gctttattgc tagttgacag aattgttgta tcattattga gcaaaccatc
     7681 aaacactttt tttgcatttg ttggatctgc atcaccacca atcacagttg ctccctctgc
     7741 taggttaacc atcatggttt tttccgcacc aacgacaacc ttagcctcat gcacaggctt
     7801 agtgctatta gtagggctaa agaattcaac cttgtaggtc tcctccttgc tagtggataa
     7861 gtccttgtga tcagtgacac ctaaggttga gtcagtcacc ttgatcttat agtccttgta
     7921 ggtcactgca aaggctttgt aatcatagct tgaatcaaca aaacggtgac ctgctatttc
     7981 ctgctcctga taagccttat agtcagcttc gctattgatt agcgtgccct gattggtaac
     8041 tgttccaaat aaaagcttag cctgcaaatc aattgtatca tttgctactg gtaactgaag
     8101 gctcttagtg ccataagtat caggataaag accagtaggc ttttgatgat caaatacaaa
     8161 cgtcttttcg ctaacaccgc catgcttagt cactgttgcc agcatggtat caagaatctg
     8221 acgattttcc gtaccagctg ctaagtccag cttattacta gagagatcca ccttttcaag
     8281 agaggttagg ctagctgcgt caattccagc caagctatca cgatcaaagc cagcaagatt
     8341 taattccttc aagccagtta gaccagaaat ggtcagagcc acctgtggaa tcgccttagt
     8401 ctcttccttc ttagcgctgt cgtaggcttc aagaacattg gccagcgtat ccttggtcgg
     8461 cttagcattt gcaggtagga ctaagctatc cagctttgtg atttgtgata gaccgattag
     8521 ctctagctta gctagttttt taagcttatt caggccttct aaactcttga tatccggatt
     8581 gtctaagcgc agggttccat tgaaccgctc taaatcccct cttctgcttc caacctgtgc
     8641 aataactgct tctcgcaaag ccttgtctgg aaaatctttc tgatcaatca gctcatagga
     8701 tttgtcattt tccataacct tcttcaaggc cttagaaacc ttataatctg atttgacaat
     8761 accatctgtt atatccttta tagccttgtt agttcttttc tcatcatctg agactttttt
     8821 aggttgatgc gctacaccat cgcgatcaat cgcataagag aaaatccctc ccttgacacc
     8881 acctgtctta ggctgccatt ttgcataacg ctcagcacga gtaccagcta tctctgaatt
     8941 taacggatta tgatcatctt tcctctcatt aatatcatac cagaggttac cactgcccgc
     9001 attttcctca tagaaagaaa aaccaaccat gtactgctca ggacgaatgt atttgctata
     9061 cgattcccaa tgttcctcca ttgtcttttc aggttttcta gcgactggat cccaatctcc
     9121 cttctcacct tgagtgccat aaacctgcac aagcagcaaa tcaatatatt gggcaccgcg
     9181 ctcaatcaat gggttcttgt cagccatgta ggtgctatcc ataatgaaca aacgtgactt
     9241 gtcagcgccc tttggcccaa taagcttgcc aatttcttca aaaacagcaa tagagcgctg
     9301 aatattttcg ttactctctt ttccatttac ttttggaatg ctatcccgct caatatcaac
     9361 atctaaacca tcaagattat atttataaac gtattcatct acaatagcct ttgccaaggc
     9421 cttatttccc tctggagtat ttgggtattt ttgcgtatct tcagcaatac cactatgatc
     9481 accgcctgca aggaaccgcc atggaatggt acgaatcaca cgtgttccct gcttgttcag
     9541 cgttggcaca tgcttggtcg ccaattcttg ccagaaaaag ctataatcct tggtccaatc
     9601 atggaaaaca aaggctaagt caacctcctt aggcaattct cccatagaat taaccttatc
     9661 cttttcagcc ggatctgatg ttttatcatg ccaagtccta aaatagccac cataaagagg
     9721 cccctttaaa ggcttcatgg ctattttttc aggaaccttc atttctgcaa gaacctttgc
     9781 ctgcttatct gcctgctgtg ccttggataa aatatccttt agcttttcag gtacttctcc
     9841 tgcctttgat aacccctcct taaattcttt tttactgttt tccgacaggt aatgtaggtc
     9901 atcaatagca gagactgatg gactagtttg cacaacctta tcctctgcct tgacccttat
     9961 gagtgaatca tgttgggcag ctaatatagc caccattaac gctgcagcac aaacacattt
    10021 cagtgttttc ttgactaaca cctgtttttc cattgggaca ctcctttatt ttgataccaa
    10081 agaatggcaa atctttgctg aaccaaaaat gtaagcgcat tctctgcgtt cgtctaaagt
    10141 atagtagacc tcatgatcaa aagcaatgca caaagtatag gtaaaataaa agaaacttaa
    10201 ggtcttttaa tttctgtaat tttatggtga atattttaat cttacatgta aaaagagatg
    10261 aaatcatcaa ctcttttcaa attattttac aaggatcact ggactgccaa cagtcacctt
    10321 accttgtgcc aaaatctgaa cagcatgaac atctgcgcta ttggtgacaa gcagcatggt
    10381 tgtagtatca aggcccgcct gctgaatcct tgcaatatca aagcttccaa gagcatcacc
    10441 agccttgacc atctgaccaa ccttaacaaa ggtttcaaag ccctcacctg ccattgaaac
    10501 ggtatcaata ccaatatgca gtaggatttc tgctccctta tctgatttga tgacgtaagc
    10561 atgacctgtc tcaagggcag cctctaccct gccatctacc ggtgagcaga gaatgcgccc
    10621 ttcaggcttg atggcaacgc cttggcccat gcttcctgac gaaaagacag gatcagcaac
    10681 cgatgacaaa tcaatcaact cccctgcaac tggactaagc agctcctcag cagcagaggc
    10741 tttttgcgca ggctctgatt ttacttgggt agccggtgct tcttggtcac tcttgtcctt
    10801 gaatccccaa atataggcaa tcacaaaagc tagaccaagc ccaaccaaca gtgtcacaag
    10861 gtactgtagt agctgaccat taagatacag cagtgcacca ggcaaaaccg taatcccaaa
    10921 gccggtacca gcaatgccaa gaatccctgc aacccagcca ccagctgcgc ccccgataag
    10981 tcctgagaca aatacctttg ggtagcggag attaacccca aagatagccg gctcagtaat
    11041 ccctaaaaga gctgacagag ctgatggaaa ggctaaaccc tttaattttg cagacttggt
    11101 tttaacagca accgctagag ttgctcctgc ttgggcggcc gtagcagctg tcaaataagc
    11161 gttaaaggga tcctttcctg tattggcaac tagctgcgcc tccaagaaat tgaaaatatg
    11221 atggatacct gtcacaacaa tcagctgctg aacaccccca ataacaaggc cggcaatccc
    11281 aaaaggcaga cctaaaactg cttgtgtccc tgcaagaaca aggttttcca aggagtgaaa
    11341 gataggccca atcacaaaga gccccaaggc actcataata gcaaaggtca aaaacggcgt
    11401 tgccaacaaa tcaagcgcat caggcacccg cttatgcagc cacttttcca gcttggcacc
    11461 aaccagacca acaaagaagg ctggcaatac cgtaccttga taaccaacaa ctggaacaaa
    11521 accaaagaaa gttaagggct taacatcacc tcctgaggct accacccaag catttggcaa
    11581 ctcattagag acgagcatca agccaaggac aatcccaatg atagggttgc caccaaatac
    11641 cctaaaggct gaccaagcaa ccaaggccgg caggtagaca aaggccgtat ctgttaaaat
    11701 ccgagtgtac atgaggaaat tgtcgccata gtcatgaata ccaaagaact ccataacagc
    11761 cggctgcgtc aagagacccc gtacacccat aaacagccct atcgccacaa tagcaggaat
    11821 gatcggaaca aagacatcac caaaggtacg aatagcccgc tgaaaggcat ttccagactt
    11881 gaccacttgc tccttttgct cacctgccaa agcagctgga agccctagag ctacaacctc
    11941 atcataaatg ctattaaccg tacctgtccc aaaaatcagc tgatattggc ctgagttgaa
    12001 aaaagcaccc ttaaccttat caatagcctc tgctttttcc ttattgatct taccctcgtc
    12061 atgaaccata acccgcagcc gcgtcgcaca atgagccaca cttctgacat tttcacgacc
    12121 gcctaaggcc tcgataacct cttttgcaat ctgatgatta tccataccga tagcatctcc
    12181 ttttttgtct gttatagtct atcgaaatag cttttcttga gcctatccaa tattggcgga
    12241 cctaccctac tgtccgactc aagatggtct ttcaatttac tattgtgaat ccgcttcact
    12301 tcttgctatc attttaacac gaatattttt tatgtcaagc gtttgacata tattttgttt
    12361 aaaataatta aaaaagttga tttttagaga gaaaacgttt atcatatgaa taaaaatgac
    12421 caatacctaa ggagacctga catggattta ccaagatcta ttcgctaccg accatatcaa
    12481 gaatggagca aggaagccta tcaagcaatc caacaaaagg tggcccagtc tttatggcgc
    12541 agccatttcc atatagaagc tcgtacaggt ctcctcaatg acccaaatgg cttttcttat
    12601 tttgctggca gctttcagct tttctatcaa aattggccct ttggagcagc tcatggtcta
    12661 aagcaatggg tacacaccac atcaactgac ttggtgcatt ttacagaaac caaaactcgg
    12721 ttgctgccgg atcatcaaaa cgatagtcat ggcgcttatt ccggctctgc ttatcctatt
    12781 ggtgacaaac tctttttatg ctatacagga aatgtccgca gcaaggattg ggtacgccac
    12841 ccactacaaa taggtgcctg gatggaccaa tcaggccaca tcacaaaatg tgagcaggtg
    12901 ctcattgaca agccagatga tgtcacagag cattttcgtg acccccagct ctttacctac
    12961 caagatcagc tttatgccat cattggtgca cagaatttgc aacaacaagg tatcattaag
    13021 ctctacaagg ctaacaacaa tgatgtcacc agctggcaat ttgttgctga cttggatttt
    13081 gatgactcag gcaccgcata catgattgaa tgccctaatt tggttttcat tgaagataag
    13141 cctgtgctta tcttctgccc tcaggggctt gccaaatcag agcttgatta ccaaaacatt
    13201 tatcccaata cctataaggt atttcagacc tttgatccta aaagacgcaa gctccttggg
    13261 ggaggtccaa tccaaaacct tgattttgga tttgaagctt atgcgacaca ggcctttaat
    13321 agccctgatg gtagggtact ggcagtttct tggattggcc tgccggacat cgactaccca
    13381 accgataaat atgcctacca gggagcgctt agtctagtca aggaattacg actcaaaaat
    13441 ggaaggctac accaagcacc agtccctgct ctcagtaagc tacgagacaa agcccagccc
    13501 tttcagaaca aaaaaaacag ctcaaactgc tatgagctgg ctttgaccat tgaagcacag
    13561 caagcaacag agcttttgct ctttgccgat acacagcaca aggggctgaa actgaccgtt
    13621 gacacctgca aaggacagct aacaattgat cgcagcaagg caggcgccca gtatgcccag
    13681 gaatttggag caaagcggtc ttgccaaatt cctgtcaatc gtgctacact taatatctac
    13741 gtagacaagt ctattctaga gatttttgtc aaccaaggcg aagcagtcct cacgagtcgt
    13801 gtctttccaa atgaggggca gtctggcatt gagctgctaa agggccaggt gagtggctac
    13861 tattatgaaa tgaggtacta gacaagtggt cgcaaaatta acagatgttg cagcattagc
    13921 tggtgttagc ccaacaacag tctcacgtgt gattaacaaa aaaggctatc tgtcccagaa
    13981 aaccattgat aaggtgaaca aagccatgcg agagcttggc tacaagccaa ataacctcgc
    14041 acgaagcctg cagggcaaat cccctcagct cattgggctg atctttccta acattagtaa
    14101 tattttttac gcggaattga ttgagcattt agaaatcgag ctctttaagc aaggttataa
    14161 agccatcatt tgcaacagtg aaaacaaccc gatcaaagaa cgagattatt tagaaatgct
    14221 agctgccaat caggttgacg gcattatctc atcaagccat aacctaggta ttgatgatta
    14281 tgagcgtgtc gaggcaccca tcgtcgcctt tgatagaaac ctcgctcctc atatccccat
    14341 catatcctct gataattttg aaggagggaa attggccgca aaaaccctgc aaaagcatgg
    14401 ctgccaaaaa atgatcatga ttacaggaaa tgatcattct gactccccaa caggtcttag
    14461 acagctaggc tttaattacc agctcaaaaa aggcgctgat attataaaac tgccaaatga
    14521 tctttccagt attcgccgcg aaatggaaat caagtctatt ttggcgacaa gaaggcctga
    14581 cggcattttt gcttctgatg atttgacagc tatcctcatc atgaaggttg ctggccagct
    14641 tggcatagca attccagata acctgaagct tatcggctat gacggtacgg cttttattga
    14701 gcattatttc ccacagctca ccaccatcaa gcagccgatc aaggagattg ccagcttaac
    14761 cgtagaagta ttactgaaaa aaataggtaa cgaaaaaacc agcaaggact atgtcttacc
    14821 gatcaccctg cttcccggag gcagtctcta agagcaatag ctcttcttct gtgattagcg
    14881 gctttcccct agcttctccc ttacttgggg cactaaagta aaaaccaaag cacgaggtgg
    14941 gaaaccctag accaccagga tacacccaga taggtcccca aaagaaagct tgataagcct
    15001 gaccacctaa caaaacctgc acacaaggaa agcttcctca agctgtcctt tgtacccttt
    15061 tcctaacaat gccaccaaaa acacatgtaa cagcaagtga cagactcccc ctatagcaaa
    15121 cagtgaccca acaaaccatc actagaagct ataaggggag cttttctatg cctaacaaaa
    15181 atctaaaatc aataacagaa aaacctaaag cagttcatgc gcacatacta cctatctgct
    15241 actattgctc taaaagcaac cggctgatcg gacaggttgg taatggtgat actatagtca
    15301 tgatcttctg tcacactata ttttctcttc cccttcaagg gaacgatgag gccatctcca
    15361 tcaatagtag ctcccttgtg tccagcttct acaataacta caccattatc cttagtggaa
    15421 tcgtattttt caataacctg ttctgttata gaataccgat atcctatctt actaagatag
    15481 ctgtctgtcc gtctataaat atattcagac catatatcac gaccttctag cttcagtagc
    15541 actttttcgt cgctttctag gtataggtca gaggaatatt ctatttgttc atactttggt
    15601 ctcaccgcaa gctctatact ctcatttggc cttagatatt cttttccttg aaaaaatagt
    15661 aaagctcata gcgtttggag aagatgaaaa cacctaccag caacatcatt aataacagga
    15721 tttttcgctt cattttgact tcttcctttt catataacca tctatacctg cttggatcat
    15781 ttgagtatca ccctcattgt ctccatagtg acctgatgat aagttcttta accactttgg
    15841 tatatcctta tcagaaaaga cctgggcaat ctcagccgcc gtttttaaat aagtccctga
    15901 agcatctaaa aagcctgtac caacataacc atagaggtag ttgccagcat agtcgcctgg
    15961 caattctgat tcccactgtc ttgaccagac agaatagtta tggccatgat aggtccttga
    16021 cttcaaatcc aagggctgac ccgtattgac aaggtcataa aattgtttgt tgtcaagtat
    16081 tgcagcactt aattgacttc cagctacctg tgaaaggtag ggagcattga cattcactga
    16141 taggatatca tctcccatct tgttgacaat caaacgaaaa ttaatacccg acgattgtaa
    16201 ttttttccct aggtcttcct caatttcctt tgcatattta ttatttttaa ggtctcactc
    16261 tccatcataa ttgcttctcg ccttccaata gtcatcaaag gctgttttat tgagaaaata
    16321 gaggtaatcc tcataggcag ctacaagtcg ctctgatttt tgtagtggcc tttcagagct
    16381 gcttttgatg gttttaatgg tctgagtcag tatgttgtga taatggtttt gagtgtactt
    16441 tgaggcattg acagggctaa tcttttgatt cttcaggcta gtcacccagc tcatatctag
    16501 gccagcagtc gagtagctgc cgtcgctgct catgaagacc tgactgagct gtgttgcgcc
    16561 ctgaatggct aaccgcaaaa taactaagct gtccctaaag cagtctgagg tttgagttag
    16621 aaaccattca aggctttcca atttggtcgt aacatctcga atccctattt ccagctggtt
    16681 tttggcatgg tatagtgtag aggtatcaga ccaaagggtg ccatagtctc cggttaaaag
    16741 actactgacc tgcttcataa acgattcgtt ttcatcaatc tgtgcttgga tcacttgcac
    16801 ttgccgttct cttagcctct tcagctcggt taagtgatca cgatccaggg ttccgtatct
    16861 ggcaatctga gcatctgccc tttgataggt ggtcaactcc acttggatag catcaatcgc
    16921 tgcttgtagc tttttgatag agggaatgat gatcgctgta aaaagtcccc tacctgctgt
    16981 ataggctgct ccctgtagct ctcccgaatc cagactagca atgagatggt cgcaaccact
    17041 tgataacctg tccgttattt cattggctat ttggatattg tttgtcatgg cttgaatcaa
    17101 ggcctttgac tctgctgcac tgtaggtcac tcccatcgta aacggctcct ttcaccgata
    17161 agctcttctt tgtccctctc tagtctacga cgaaccccca tcgtatagat tgacacgtga
    17221 tccagatgct catcaacata gcgatccatt tgtctgatca agtggtcatt ggcctcttgc
    17281 tctgcgtact ttccagctta gtcctcaggc atatggttca atagggactc aagggcaaaa
    17341 gagaggtgct gacagtctgc ttgaatctcc gagactgctt gttcatgccg tcgtttcatc
    17401 gacaaaagat cctcctctag ccactccagc tcattgatct gtcgggttag ggcaagaaat
    17461 ttttcttcag attcttcttt gatcatgact tattccccta tcttgttgct tcctctaggt
    17521 ctcttttctc taatttggcc gcaagctgag gaaatttatt agcctgaata aggactgcct
    17581 gactaaagtc gctgacagcc tgcagcagtt gattagagac ctgacgtccc ttttccatac
    17641 ctgcaatacc cttggtcaca ctaaatgcaa cggactgttg gtgaacccta ctggtgtcta
    17701 cacctaccaa ttcactaata gcagcagaag cagccacagg gcttgatgta atggtatcac
    17761 tcatacaatt tctcctttat aacccttatg tcttttatta tatcacagga taatagccat
    17821 tgtgcttata gctcttacct aaataatagc aactgat
//
LOCUS       DARYMD010000040        16867 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYMD010000040 DARYMD010000000
VERSION     DARYMD010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16867
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(188..940)
                     /gene="pstB"
                     /locus_tag="TU818_001413"
     CDS             complement(188..940)
                     /gene="pstB"
                     /locus_tag="TU818_001413"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL0924218.1"
                     /translation="MGAFSTKQLNVFYGAFQALKDISIDIPENQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEVLLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKTLDQLVEQSLRGAAIWDEVKDSLKKSAMSLSGGQQQRLCIARA
                     LAVAPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            complement(942..1757)
                     /gene="pstA"
                     /locus_tag="TU818_001414"
     CDS             complement(942..1757)
                     /gene="pstA"
                     /locus_tag="TU818_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL0924219.1"
                     /translation="MTNYLLKALVYLLSLLTFGSLFLIIAFMLIKGLPSLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVVFFGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKIVLPAAMPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            complement(1750..2613)
                     /gene="pstC"
                     /locus_tag="TU818_001415"
     CDS             complement(1750..2613)
                     /gene="pstC"
                     /locus_tag="TU818_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL0924220.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAIIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGFGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTNIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSAHD"
     gene            complement(2683..3555)
                     /locus_tag="TU818_001416"
     CDS             complement(2683..3555)
                     /locus_tag="TU818_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL0924221.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKVNGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVKEKTADIGMVSRDLTTEESKGLIDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            complement(3714..5039)
                     /locus_tag="TU818_001417"
     CDS             complement(3714..5039)
                     /locus_tag="TU818_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL0924222.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLVVLCTGLVASF
                     YVLSMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFVVLEDLKRMDLIALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEILVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRNFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            complement(5023..5745)
                     /locus_tag="TU818_001418"
     CDS             complement(5023..5745)
                     /locus_tag="TU818_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0924223.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            5917..6072
                     /locus_tag="TU818_001419"
     CDS             5917..6072
                     /locus_tag="TU818_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924224.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     VKTAKQD"
     gene            6113..7015
                     /locus_tag="TU818_001420"
     CDS             6113..7015
                     /locus_tag="TU818_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL0924225.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESTQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFISVSAVMITIYCLLVGVL"
     gene            7015..7830
                     /locus_tag="TU818_001421"
     CDS             7015..7830
                     /locus_tag="TU818_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL0924226.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQLHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(8015..9436)
                     /locus_tag="TU818_001422"
     CDS             complement(8015..9436)
                     /locus_tag="TU818_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL0924227.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTDGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKVYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(9463..11325)
                     /locus_tag="TU818_001423"
     CDS             complement(9463..11325)
                     /locus_tag="TU818_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL0924228.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSMIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVATGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDTVK
                     QGQPLLRIDLELIGSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            complement(11330..12169)
                     /locus_tag="TU818_001424"
     CDS             complement(11330..12169)
                     /locus_tag="TU818_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL0924229.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGMIISDPLRWEIRRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEVSIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLMVKDKYPEEYHCVRQISHHMKKAYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            complement(12458..13915)
                     /gene="ftsY"
                     /locus_tag="TU818_001425"
     CDS             complement(12458..13915)
                     /gene="ftsY"
                     /locus_tag="TU818_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL0924230.1"
                     /translation="MGLFERLFGKKDKTKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTNAHAVAADVVSRTDDTSKQAELSDEAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQAETNAEYQVAAQAPAG
                     SADQPAEEGQKQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATTLTEELRYEAKLENAKKPEALKRLIIDKLVAIYEGDGRYNEAIH
                     YQPGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAERADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            complement(13915..14742)
                     /locus_tag="TU818_001426"
     CDS             complement(13915..14742)
                     /locus_tag="TU818_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0924231.1"
                     /translation="MTRIKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDVISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDQQLARLPKTIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLQWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            complement(14743..15540)
                     /locus_tag="TU818_001427"
     CDS             complement(14743..15540)
                     /locus_tag="TU818_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0924232.1"
                     /translation="MVKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDHLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKILANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPEKTIAFGDN
                     LNDYQMLSFAGQAIATENARPEIKAISDQVIGHCNDSAVLTYLEGLV"
     gene            complement(16058..16567)
                     /locus_tag="TU818_001428"
     CDS             complement(16058..16567)
                     /locus_tag="TU818_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924233.1"
                     /translation="MKKKAYMTLILLIGILAIFLVGKQVIKKENPNKPTVDLTVYTIS
                     SSDTQKWNKVRQLETEEAIYLIRVKEAASSEEIFSNIIADGAAMGFGVSEEDVKQFNN
                     HLENTIEDSKNNKLIEMEFFDFSNNNKGFVVANFDYGKKEFNAQKKEKKALYKKLYEA
                     FKEKNHQSR"
     gene            complement(16564..>16867)
                     /locus_tag="TU818_001429"
     CDS             complement(16564..>16867)
                     /locus_tag="TU818_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0924234.1"
                     /translation="IADVLEKVGLSNDYLNQKIYELSGGQVQRVAIARMLMKPRKIIL
                     ADEPTGALDSEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDVIIDLKDIGSEI"
BASE COUNT         4841 a         3982 c         3177 g         4867 t
ORIGIN      
        1 ataccagtaa cctttgtctg aaaatagcta gatcgtgctt atcaaagaaa gcaaaaaagc
       61 ttcactctac aggaagtaag agagaagctt ccacgctaat aggatactga tctgacatca
      121 tcaaaacacc aattgaggag agatttagcc ctcattccaa ttgctctttc atcgcctagt
      181 ccttttctta tccgaagcgt ccggaaatat aatcctctgt acgcttgtcc tttggctttg
      241 taaatagttc agctgtatcg ccaaattcac aaatatctcc tgtgaggaaa aaggctgttt
      301 tatctgacat gcgtgaagcc tgctgcatgt tgtgggtaac gatgataatc gtgtaatcct
      361 gctttaattg ctgaaccaag tcctcaattt ttaaggtaga aatgggatca agagcagagg
      421 taggctcgtc catgagcaac acatcaggtg ctacagcaag cgctcttgca atgcaaagcc
      481 gctgctgctg tccacctgat agggacatgg cactcttttt taagctgtct ttgacctcgt
      541 cccaaatggc tgctcctctc aaggactgct ctaccagctg atctagagtt ttcttgtcct
      601 taaggccatg tgtcctagga ccataagcca cattatcata aatagacatg gcaaatgggt
      661 tgggctgctg aaagaccata ccaacacgct tacgcagact gttgaggttt attgctttag
      721 catagatgtc ttgattgtct aagagaacct ctccttcgat acgacaggaa ggaatcaagt
      781 cattcatgcg atttagggtt tttaaaaagg ttgatttgcc acagccagag ggacctatca
      841 gggctgtgat ctgattttct ggtatgtcaa tggagatatc ctttaaggcc tgaaatgctc
      901 cataaaagac attaagctgc ttggttgaaa aagctcccat tttagacgac tcctttcact
      961 aatcggcgtg ataataagct tgatagggca ttgatcagca agacagttat gagtaagata
     1021 acacccgttg cataagcttc cttgacatgt agcccttcgc tagacagcat gtacatgtga
     1081 agagctagtg agcgtcctga tgacatgagg ctggttggcg tattggtaga ggtgcctagg
     1141 gtatacatca gggctgctgt ctcacccaca acacgtccaa tcgctaggat taccccggct
     1201 agaataccag gcattgcagc cggcagcact attttaaaaa tcgtccttag cttacctgct
     1261 cctaagccaa ggctagcctg acgcaagtga tcactaacag agaggagcgc ttcttctgtt
     1321 gatcgaatga taactggcaa caccatgatt acagacgtca gaatacctga taaaagagaa
     1381 tattgcaggc cgaaaaaaac cacaaagaac agcatgccaa aaagaccaaa aacaatcgaa
     1441 ggaatccctg atagcgtatc agctgcaaga cgtattgccc ttacccatag tgagtcctgc
     1501 ttagcgtatt ccacaagata gaagccagca aagacaccaa tgggcaaggc tagcactaag
     1561 gtgcctaaaa ctagactaac agttgagata atcgacggca ttagagaaac attgtcagag
     1621 gtataggtcc atgaaaataa ggataacgac agactaggca agccttttat cagcataaag
     1681 gcaataatca aaaataagga gccaaaggtc aatagcgaca aaagatagac cagggctttt
     1741 agtaaatagt tagtcatgag ctgattttcc tttcacataa gcaaagcaag cattaatgat
     1801 gagaataaag ccaaagagga cagccgatgt tgcaatcaag gcctctctat gctgaccaga
     1861 agcatatgcc atctctagga caatatttgt cgtcatggtt cttgtgccct caaataatcc
     1921 tgatggcagc acaggctggt ttcctgctac caaaataact gccatcgtct caccaatggc
     1981 acgaccaaat cctaaaataa gagcggaaaa aaggccggat ttggctgctg gcaggatcac
     2041 tcgaaaaata ctcctttcat gactggctcc cagtgcaaga ctagctgaat aataagcctt
     2101 tggaacagct ctgatagcag actctgaaag actgataagc gttggcaaaa tcatgattcc
     2161 taagagcaag gaggcagtca gcacactcat gccattacca gcaaagctcc taatccaagg
     2221 cactagcact tgaagaccaa aaaagccata aacgatagac ggaatggctg ccatcagatt
     2281 aacagctgac tttaaaaagc catagcatgc tttaggacaa tagtaaacca taaaaactga
     2341 ggtcaatata cctgttggca caccaatcac cattgcacca agtgtgatga caaaagaccc
     2401 tgcaatcatc ggcaaaatac catagcttgc cggctgattt gacggtgacc aatcatttcc
     2461 tagcaaaaag gctctcatac catacttagc aataaaggga aggccattac taaaaataaa
     2521 gatacagatt aaacaaatag caataattgc catcgctgca ctgagaaaga agataacttt
     2581 aaaaaaatcc tctttaaagg cttgtttatt cactgatgat cctttctaag aaaggaaagc
     2641 aagaacaaaa cacctcttct ttgccttcct tctaatcgtt ctttatttga ctttgtccca
     2701 gcttgttagc ttgccgctaa agacatcagc cagcacatct atgccaatat tacttacctt
     2761 attgtccttg tgaacaatca ctacgatacc atcaagggca atcgcatcat caattaagcc
     2821 cttgctctcc tcagttgtta ggtcacgaga aaccataccg atgtctgctg ttttttcctt
     2881 gacggcggtg atacctgctg atgagccatt tgaggtaata tcaatgctaa tggctggatt
     2941 ttctttcttg tatgcttctg ctaatttttc catcaagggt gaaactgagg ttgagcctac
     3001 aattgacagc ttgcctgata agcccttact gctataggct ggcgcgtctg tttttgcttc
     3061 gatcaatcga ttgtctctaa caatctcctg cccctgcttt gagtcaataa aggtgataaa
     3121 atccttacca actcctgata ggtctgagga ccatacaata ttaaagggac gctgcagagg
     3181 gtatttcccc tctaaaatag tctcacgact agcctttacg ccatttacct ttagggctgc
     3241 aacgtcgcta tttaaggacc ctagcgagat gtagccaatg gcacgactat ttcccttaac
     3301 agaggagatg accccttctg tgctattttg gataatagct gtttttgctg tttggtcaat
     3361 ctctttgtca ccgtcctttt ttagaatgcc tgtcatttcg gtaaaggctc cacgagtacc
     3421 tgagccattt tctcgagaaa caaggtcaat cctgtctgct gcttttccag catcagcact
     3481 gttattgcca caggctgcaa gacctaagcc tgataagcca atagctgcca tgatcagcat
     3541 ttttttgatt gtcataagaa tcacccttat cttttatgat attgtgttgt aggcttgcta
     3601 cacctatagc ttatcaggtc tttgtaaagg tttatccctg attaatgtaa agattttgta
     3661 aaacctaaaa cagccactac caaggctggc cttaagtagc tggtagtgac tgtttacttg
     3721 ttgatagctt ctggtaagaa taaggtaaat tggctgccct ctcctagctg acttgtgact
     3781 gttatctgac cgccaagaag ctgactcagc tcctttacaa tggctaggcc taggcctgtt
     3841 ccaccacttt gcctgctacg tcccttgtta acacgataaa agcgctcaaa aatacgatct
     3901 agctcaattt ggctaatgcc aatcccagta tctgcaactg taatggcaac accaccagca
     3961 accctttgac tggatagctg aattctgccc ccattgtctg tatactgtat cgcatttgat
     4021 aagagattta acatgatctg cgataagagg tattgatcag atgtcacaac aatcgaatcc
     4081 tccaatgcat agcttagctc aagctgcttt tgctctagct gtggtctcat gctctgacct
     4141 gtatacagca ggaagttcct gagctgaaac tctgtcaggt caagtggtgt cttgttagcc
     4201 ttggataagg tcagcaggtg ctcaacaata cgttctagac gcaagctttc attgtagata
     4261 atgtctaaaa agtcttcttt taggcttgtt tcatcgtcag gcatttcctt aatcgtttca
     4321 gcaaagccct tgatcgatgt aaccggtgtt cttaattcgt gagaagcatt agcaataaac
     4381 tccaaattta gcctctcata atgacgaatg gccgtcagat catataagag cactaaaatc
     4441 tccttgacaa catgcgactg gttaaagata ggcacaaggg taacctccaa gatcaaatca
     4501 ccatcatgta ggcctgttaa ttccttcttt aatgtctgct tttggtcaaa gacttgatta
     4561 actaaggcta tcagatccat tcgtttaaga tcctccaaga ccacaaaagg tggcttagcc
     4621 tctggaaaat aagccggtaa ggatttgctg gtcagcaaca gctccctttg attggagact
     4681 aaaagcatgc ccatcgtgag atgagaggtt acagcctcca cattttttga taaggctttt
     4741 agccttgctt ccttttgtaa taggtcactt tttagctctg tcagctgctt agcataagca
     4801 cttaaatcag cctgccccac taggagaaaa tggtcactag ctgtcaaaag atggtggtgc
     4861 aaggctctga attcacgctc ccatctaaat agcatgctca agacataaaa gctagctacg
     4921 agaccagtac acagcactac tagagtcagc acctgatgcg gcccttgcca aatcagacca
     4981 agagcagcca gcaagcaaag ccctagcagc atgctcaaac gcctaagatg tcctatcatt
     5041 ctttagctcc ttaaatttgt agccatagcc gcgaatggtt tgaatatact gaggcgcctt
     5101 aggattgtcc tcgatttttt ctctgagctt gccaatatga acgtctacca gacgtgtttc
     5161 ttggccaaag tcataacccc agatacgctc taatagccgc tcacgcgtca gggtcatatt
     5221 agggtgcttc atgagataga gcagtagctc atattccttt ggggttaacg gcaatagctc
     5281 cttgtcctta tagacctcat gtcgctctgg gtacagacgc aattgactca tcgtataaaa
     5341 aggctcacga cgctcttcac catcaccaga aatctctgct tcagtacgcc ttaaaatagc
     5401 cttgacacgc gctaataatt ctctaggact aaagggcttg gtcacataat catctgcccc
     5461 cagctccaaa gccaaaacct tgtcaaattc atcactttta gcagaaacca tcataattgg
     5521 ggttttgctt cccttagcac gaagcctttt gcagacctcg ataccgtcta attgcggcag
     5581 cataatatct aacacaataa aatcataagg ttctctttca gctaatgcca aggcagtacg
     5641 gccatctgtt accatctctg tcacaaagcc ctccttggcc aagtgataat ccagtagcct
     5701 taagataggc tcctcatcat ctactaataa tactcgtttt gtcatttcat agctcccatc
     5761 agccacatta tatcatattt gtcagtcaat ctaatgacac actgcttgac ggcctgaagc
     5821 ctaaaatcaa tcagaagata aaaagatgtt ttagctttgg ctttaccgtc aaatgattgt
     5881 ataatagagc tatattgatt gaaagaaggt atacctatgg caattactca taagaaaaat
     5941 gaccagctcg aaaagatgat ggcaggcttt gcgtctatcc cagattttga taagccttta
     6001 gagcttaacc aagatggaaa gctagtcact gaaaaaccaa agccacaagt caagacagct
     6061 aagcaggact agcccttatt ggcgtcgtta acatatagaa aggatacggt gaatgtcgct
     6121 tttttcaaat ctgccaccca gcgtgcttca atggtttgcg atttttctat ccattatcat
     6181 tgaagccctg ccttttgtat ttttagggac tattttatct ggctgtattg aggttttcgt
     6241 cacgcctgat ttagttcaaa gatacctccc tcaaaataag tggctaagaa ttttatttgg
     6301 tacctttatt ggctttgttt ttccttcctg tgaatgtggt atcattccta ttattaatcg
     6361 ttttttagaa aagaaggtgc ctagctacac tgctgttccc tttttagcaa ccgctccaat
     6421 tattaatccg attgttttat ttgctaccta ctctgccttt gggaattcgc tgcgctttct
     6481 catgctaagg cttttaggcg ccattttagt ggctgtcagc cttggcatca tgctagcctt
     6541 cattgttgat gagaacattc tcaaggaatc aacccagccg gtgcattgtc atacttacag
     6601 tcacgaaagc ctgccaaaac ggctttactt ggcactggct cacgctattg acgaattttt
     6661 tgatacagga aggtatctag tctttgggac cctgattgct tcagccatgc agatttatct
     6721 gccaacaaag gtgctgacag cgatcggaca tagccctttg acagccatct tagtcatgat
     6781 gctcttagcc tttatcttat ctctttgcag tgaggctgac gcctttattg gagcttcgtt
     6841 attgtcaacc tttggagttg ctcctgtttt agcctttctc ttaatcggcc ctatggttga
     6901 catcaaaaac ctcatgatga tgctcaattc ctttaaggga gcctttattg ttcaatttat
     6961 cagtgtatca gctgtgatga ttaccatata ttgcttactt gtgggggtgc tgtgatgatt
     7021 cgctttttaa ttttagcagg ctattttgag ttgaccatgt atctagagct atctggcaag
     7081 ctaaatcaat atatcaatat tcgttacgct tacttagcct atatttctat ggttctatcc
     7141 tttatccttg cattggtgca gctatacact tggactaaaa acatcaagct acacagtcat
     7201 ttaaaaggta aggtcgctca gctgaccagt ccccttatcc tggtctttcc tgttttggtt
     7261 ggcttgttag tacctacagt cagcttggat tcgacgaccg ttgccgccaa gggctatacc
     7321 tttccattag ccgcaggcgc ttcaaaaaca ggggtcagtg atgatggtac tactattcaa
     7381 tacctaaagc cagacaccag cctgtacttt accaaatccg cctatcaaaa ggaaatgctc
     7441 aatgaactga aaaaatacca aggcaaatca gccatcacca ttaccactga caattatatg
     7501 gaggtaatgg aattaatcta cctttaccca gacgaattcg ttgatcgtac gattcagtac
     7561 actggctttg tctataatga gccaggacat gacagctatc aattcctctt tagatttggg
     7621 attatccatt gtatcgctga ttccggtgtg tatgggcttc tgaccactgg taatcaagaa
     7681 agctatgcca ataacacttg gctgaccgtc aagggccagc tgcacatgga atatgacaag
     7741 accctagagc agcagcttcc tgtccttcaa atcgaggaag cacaccaagc cccagagcct
     7801 gataaccctt atgtctatag ggtattttaa caagcattaa gcctccacac ctatgacaca
     7861 ggtctatgga ggctttttgt taggggacag tacaaagacg taattgagtt cgttccattt
     7921 aaatgaaatg gctaaaagcc gtatagcatc agccttttaa aagacgtgtg ctatacggct
     7981 ttgctattgt tggtaaagcc tttgaggcta ctttctagct ctcctcagac aggctacgcc
     8041 cattggtctc aatgaccctt tgataccaag caaaggattt tttcttgtag cgtgtcaaat
     8101 gaccactgcc atcatcatgt cggtcgacat aaataaagcc ataacgctta cttagctgag
     8161 cagtcgacat agaaacacaa tcaatacagc cccaggaggt atagcccata atgtcaacac
     8221 cgtcctcaat agccttagca acctgcaata aatgctgcct catgtaatca atccgataat
     8281 cgtcctgaac tgtccagtga ccatcctttg tctgtactag cttatctttg gcgccaagcc
     8341 cattttctac aataaagaga ggaatttggt acctatcata gtaatcattc aaggttatgc
     8401 gaaggccaat tggatcaatt tgccagcccc attccgaaga gggcagatga ggattaacca
     8461 agccacctaa aatattgccc tcccctcgtt gataatgatc cgggtgatga gactgagtca
     8521 cactcatgta atagctaaag gataaaaagt caaccgtatg ctgcgccaaa agctcactgt
     8581 cgcccggttc aaattgaatg tcaatgtgct gctccttaaa aaaggatttg gcataggaag
     8641 ggtattttcc tctgacctga atatctgaga acaggagatt acgttgctca aactgcttcg
     8701 cagctaaaat atccctcgga tcagaggtca ttggataggc tggcatagcc aaaatcatac
     8761 agcctatttt aaaagcaggg ttaatcaatc tagcaagcct tgtcacacta gcagacgcta
     8821 ctaattcatg gtgaatcgct tgataaagct cctgcggagt cagcttttcc tttggtgtca
     8881 tgatagcacc actggtaaaa ggcatatgca ggattgaatt aacctcattg aaggttaacc
     8941 aatacttaac cttgttcttg tagcgctgca tgacagttgt cgcaaaacgt tcaaagaagc
     9001 caaccatacg acggtcagtc cagccattat agaccttagc tagatgcagt ggggtttcgt
     9061 agtgagatag ggtcactaaa ggctctatgc catgtgctat cagctcatca aacaaatcgt
     9121 cataaaattg tagccctgct tcgttaggct ctgtctcatc gccctgagga aaaatacgag
     9181 accaagcaat tgatgtccgg aaaaccttaa agcccatttc tgcaaagagc gccacgtcct
     9241 ccttgtagcg gtgataaaaa tcgatggcct ctagcttcaa attagctgct gttggctcag
     9301 ctgtatagtc tcctaagccc ccttctggta aaacatcctg aaccgacaag cctttgccat
     9361 ctgttaaata agctccctca acctgattgg cagcaactgc ccctccccac aagaaatcct
     9421 ttggaaaaca aaccatatta tctcctcctt caattcatct ctttagagaa taacgagagc
     9481 aacatcatgc tgagtgatat gctccttgtt gtcattaaca atgatttcga gctgctcaga
     9541 gctattggtc accacaaatg gagtcactaa agaatagccc ttagagccaa tcaattcaag
     9601 atctatacgt agcagcggct gcccctgctt aacagtatca ccagccttaa ccagctgctc
     9661 aaagccctgt ccttttagct caaccgtatc aataccaaca tgaattaaga cgtcaactcc
     9721 cttggcgttc tttaaagcaa tagcatgctt tgttggaaaa agggtgataa cctcgccatc
     9781 aaatggggca tagacatatt cctcattagg taaaatagcc agcccctctc ctaaaagctt
     9841 agacgaaaag gtttcatctg gcacctctga taatggaagc actgtgccaa ccatcggagc
     9901 ataaatagat tgctttgctg ataagccact ttttactggc gtgctatccg agtcagctga
     9961 cccctcctgg tcaacctcct catcaatgcc aaaaaaccag gttaatgtaa aggttagagc
    10021 aattgttaag cccgctgcaa ttaaggcatt ggtaaaatta gcagagctag tcgggctaat
    10081 gtattgtggc aatccaatta gtgatggcac cacaaaagta taagaggcta tattaacaaa
    10141 gccaatatag gcgcccacaa ggccaccaga aatcattgca gcatagagcg gctttttaaa
    10201 ctttagagta atgccataaa gagcaggctc tgtaattcct gccaataaag ctgataagcc
    10261 tgctgctaag gcaacctgac gggtttgctt ttgctttgat tgacatgcta cagccaccgc
    10321 tgctgatccc tgagctaggt tagaggctag cattgctggg aggattaaaa catctggagt
    10381 tgctacagag gccgccagaa aaataggagc aaaggcccaa tgcatacccg tcataacaac
    10441 aagcggcata attgcaccta aaatagcaag agccagccaa ggagcaatat ggtaaatcgc
    10501 tagcaggcta ttagacaagc cctgtcctat aataacaccc agaggtccaa taacaactaa
    10561 ggctagaaag cctgaaataa aaataatcaa ggtcggctgc aggaagctct tcatcacact
    10621 cggtacaaaa cggttaacct ctcgctcaat gtattgcatc aggtaaacca taattaaaat
    10681 cggaataact gacgcaccat agctagcagg tgtcaccggc gctccaaaca aagccatagg
    10741 tttacctgta gctaccatcg taacaaaagc tgggtgtagt aaaatccctg caacagttgc
    10801 tgctaataca ggtgtgacct taaagcgtgc cgcagctgaa tatgcaatca tgattggcat
    10861 aaaataataa gcagcatctc caaaaaaatt aataaaagca actgtttgag agtccgtacc
    10921 tgctagacca agcataggca ccaagatccc aaccaccttt aacataccgc ctcccagtaa
    10981 ggcaggtatc agtggagtaa tcacactagc tatcgtttca atcaaccctt caatcataga
    11041 ctgcttttga ccagcgctag agctcatatc agtttcatga aactgtccta gggtcataaa
    11101 tgccttataa taattgttaa catcgtttcc taaaataatt tgatactgac cgttttggcg
    11161 catgactcca atcacattag gaataagttt gattttttga tctaccactt gtttatcatc
    11221 tttcaaaacc aagcgtaacc gcgtgatgca gtgggttacc tcttgaatat tctgctcacc
    11281 accaactgct tcaaaaatgg ccttggctgt ttcttgataa gtcatttcat tactccttca
    11341 catttttgac taaacgtttg atatgaaccg ttaaatacaa aagctcacta gagctaagct
    11401 gataatggta tgcttttttc atgtgatggc taatttgcct aacacagtga tattcctctg
    11461 ggtatttatc cttaaccatc agcagcaaat cagtctcgtc atcatcataa gccatgcctg
    11521 ataacacgcg ctgagcaaat agcttcacat gagtgataaa gcgataataa tcaatagaga
    11581 cttcatcaag ctctgtctta aaatcagcct tgaccttctg ttcaatgtaa gacacaattt
    11641 ctgtcattcg atgaggctcc ttgaaaggat tatcaaggct cgcgttgaca aagtgcatcg
    11701 caataaacga agcttcatct acagccagag cgactcctag ctcactggca atgacctcta
    11761 aggccttaac gccaatcgca tattcatcag gataataccg tctaatctcc cagcgcaagg
    11821 gatcactaat gatcatcccc tgcttatgtc tttcaatagc tgaatgaata tggtctgtca
    11881 aattgatata gagtatttca tctaaatttt tacccagctt aattttccct agattaataa
    11941 gcctctctga gcaagcaacc acctcttgcg gaacagcaat aaataattca gtaaaacggt
    12001 tcatattgtc actatttttt aaaacaaatg acgcttcgat agcttcacta tcgatatggt
    12061 caccaattct tttcttaaaa gcaatcccct ttcccatcaa aagaatatct agcccctgat
    12121 ggttggtcga aatcgctgca ttatggttta aaacgcgttt aataatcata aaagtcctag
    12181 tccctcattg cttcacaata aaaaatgacc tatccacagc atgctaaaag gccacactgg
    12241 aataggtccc tgctcacaaa actgtgataa catcctttaa tattctgatt catttgtcat
    12301 tagcacgctt accctaagta atcacatcta ataacgtttt cattttatca tctcctaaag
    12361 gtcctgtcaa gcgttttcaa aaggctgttt gacatttgcc tctaaacgaa ccccctcatt
    12421 ctctttggcc aacagccgat aatctgaggc tttcctctta aagtatgcct tctaatagtc
    12481 ccttcataaa gtcctcagag tgaaattcac cgatatcatc aatagcctca ccaaagccaa
    12541 tcagcttcac tgggatatcc aattcctgac gaatagctag gacaattccc cccttagctg
    12601 taccgtcaat cttagttaaa atcaagcctg tgagcggtgt gatttttgaa aactccttag
    12661 cctgactcag agcattttgc cccgttgagg catcgagcgc tagcagggtt tcgtgtgggg
    12721 catcaggtat gacacgctta atgattcgtc ctattttttc aagctctgcc attaggttgt
    12781 ccttattttg caggcggcct gcggtatcaa tcaggagaat atctgccctt tcagcaacag
    12841 ccctctcaac gccatcaaag accacagagg ccggatctgc tttttcaggg cctgtaatga
    12901 ccggcacatc aacccgtcgt ccccattcaa ccagctgggc aaccgcgcct gctcggaagg
    12961 tatcagctgc aacaagcata accttttttc cctcttgctt ataccgataa gctagctttc
    13021 caattgatgt tgtcttacca acgccattca ccccaacaaa gagcataacg gtcaagccag
    13081 gctgataatg aatcgcttca ttgtagcggc catccccctc ataaatagcc actagcttat
    13141 caatgataag acgctttaga gcctctggct ttttagcatt ttcaagctta gcctcatagc
    13201 gcaattcttc agtcaaggtt gtggcaacat gaacaccaac atctgagaga atcaaaagct
    13261 cctctaagtc ctcaaagaag tcctcgtcaa cacgtctaaa gttagcaaag aagctgttca
    13321 agcgtgctga aaagcctgta cgggttttct ttaagctgcg cttgtatttt tcctgatcag
    13381 attcagctga tagggtctct tgcttttggc cttcctcagc tggctgatca gctgaaccag
    13441 caggtgcttg agctgctact tgatactcag catttgtctc tgcctgatct tctgttgatg
    13501 cgtctgcgct ctcgttacta tgctctgact tagccctatc atgcttagcc tcctccatag
    13561 cctcgtgctg gcttaggctc tcacctgcct gatccaaggt cttgtcatca gtagctgcta
    13621 actctagctc cggctctctt tctaaaagaa aagctcctct agctgctgga tcaagccctt
    13681 cagcttgctc tgaagcagcc tcgtctgaga gctcagcctg tttgctagtg tcatcggtcc
    13741 tagagaccac atcagctgcc actgcatgag catttgtatc tgataaggcc tccttttcag
    13801 actcaatcgt atcctttgac gttatgtcct ccgacaatac ctctgtagtg gcagcctctt
    13861 gctcagcaac cttagtctta tccttttttc caaataagcg ttcaaataat cccattagcc
    13921 ttcctcattt aaaatatatt tccaaatagc ctcagccaca cctgattggt cattggttag
    13981 ggtagtcact gcatctgcca cttccttagc ctgatcaacc gcattggcca tagccacacc
    14041 aagacctgcc cattgtagca tgctaaagtc attggcctca tctcccatcg ccatgacatg
    14101 cttggcctcc aagcccaagt gctgacaaag caggtccaaa ccaaatgcct tatgaatccc
    14161 cttaggcata atctcaaaga tgatgtctcg tgatttaaag gcctcaaaat cctcaaagat
    14221 agtctttgga agccttgcaa gctgctgatc caagaccttt ggatccgtca ccgtaacaat
    14281 tttattgtat gtgatgtcct ttggcagctc agcaaatgat ttaaggctaa caaagttcag
    14341 caagggactt gccaagtgat actgagagcg tctgccatca ttgcctgata gactataaac
    14401 agtaccatca ctgataacat cagtaggtaa gccaaccgct gccaactgct gatgaatgtc
    14461 ataaacctca gcaaggctta gagcgctttt atctaaaata tgaccagtat ttcgttgaac
    14521 cagaccgcca ttaaaggtaa tgctatagtt ctcttcacct agcaaatcca gctcctcaag
    14581 caaatttccg atagccttaa gaggacgtcc ggttgtgata acaaccttaa ctcctttttc
    14641 cttagctgct gctagagctt ttttgttctc atcactaacg attttttcgg tattatagag
    14701 agtcccatct aaatctagag ctaaaagctt tatacgcgtc atttacacca atccctccaa
    14761 ataagttaac actgctgagt cattacaatg accaataacc tgatcagaaa tcgctttgat
    14821 ttcaggcctt gcattttcag tagcaatagc ctgccctgca aaggacagca tttgataatc
    14881 atttagatta tcgccaaagg caatggtctt ttccggtaaa atgcctaggt gctgacacag
    14941 ctgatccatg ccaaagccct tatgaacctc ttttaggata atatcaatcg aatcaaagcc
    15001 agtcgtcacc gcagaagcat aggacagctc ctgatttagc cagtcactgc cagctaagac
    15061 tgtttctcct gtaaaggtcg ttgaggcttt aaaaacagtg tcatcaacaa tatcctgcag
    15121 acaatcaata agctgaacat tttcataata ataatgcatt ttttggatat aatcctccgt
    15181 agctcctttg agcacatagg ctgccttttg ccctgaaaag aggatcccag actgattgta
    15241 ataaggattg gcaagaattt tctctacaat gtcatgacac tgctgcttgg tcatgacatc
    15301 agcaaaaaga atgtccctct tgtattgcac cacagaccca ttctcagcga taatggcaat
    15361 gtcatctaaa aaaggctcaa acaagtgatc aatggctaaa agcgaacgcc cactagaaac
    15421 tgtaaagaga atcccttttt ctcttagctt aggcaacaga gctgccaagc gctccttgtc
    15481 ataagttccg tcctctctta aaaaggttcc gtccatatct gttgctatca atttaaccat
    15541 acaatttaac catttccttt ttagggagat actgattcag ctattcagct ctcccaaaaa
    15601 tctctttttc cattatacca tatctaaaca aaaagggcgt gcctgtccta acacgtcctt
    15661 gttttaaggc tttataattt ctgtagtggg taactccact gtggagatta ttgagccctt
    15721 attccaaggc tttctttatg ttctattgta tcaatttcct tattccaatt tctgttgcaa
    15781 ttaactttaa catacaatct aaccatttca ctttcaaggg agtgcaaaac ccgagtgggg
    15841 tgtgcaactc aaatcccagt ataactcctt tcgttatacc acaggtagac caaaaaaggg
    15901 cgtgccatct gacataccct tgttttaaca gtcaatctga gctccgtttt taaaggctaa
    15961 acttctttat ctccatactc tcaacgctta tttgccataa ttcttaattg aagcccgtca
    16021 ctaagttttc ttgttactaa agagttgagt aatgaatcta tctagactga tgatttttct
    16081 ccttaaaagc ttcatatagt tttttatata acgctttctt ttcttttttc tgagcattaa
    16141 actctttttt accgtaatca aaatttgcta ccacaaaccc cttgttattg ttagaaaaat
    16201 caaaaaattc catttcgatt aatttgttat tcttagaatc ttctatagta ttctctaaat
    16261 gattgttgaa ttgtttaaca tcttcttcac taactccaaa acccatagca gctccgtctg
    16321 caatgatgtt tgaaaatatt tcttctgaag atgctgcttc ttttaccctt attaggtata
    16381 tggcttcttc tgtttctaat tgtcttactt tattccattt ttgggtatca ctagaagaga
    16441 tcgtatagac tgttaaatct accgtaggtt tattgggatt ttcttttttt attacttgtt
    16501 ttcccactaa gaaaattgcg agtattccaa ttaataatat caacgtcata taagctttct
    16561 ttttcatatc tcactcccta tatctttcaa atcaatgata acatcaacct tattatatac
    16621 agctggatca tgtgttgcta taataacata tttattttcg gctgtttcac tcaataataa
    16681 attaatgatt tcttttccaa tctcactatc caaagctcct gtaggttcat ccgctaaaat
    16741 aattttacgt ggcttcatta acattcttgc aatagctaca cgctgaacct gtcctccaga
    16801 taattcatat attttctgat ttaaatagtc attagaaagt cctacttttt caagtacatc
    16861 agctatt
//
LOCUS       DARYMD010000041        16673 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.042, whole genome shotgun sequence.
ACCESSION   DARYMD010000041 DARYMD010000000
VERSION     DARYMD010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16673
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            117..1367
                     /locus_tag="TU818_001430"
     CDS             117..1367
                     /locus_tag="TU818_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL0924235.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQILAQVRGQEFDKELAQRLESEM
                     KLQEARANNRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDNNGVEILSIMFEMKNEVDTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEHFKHAFAKNYQSASNNFKKAVDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            1476..2357
                     /gene="truB"
                     /locus_tag="TU818_001431"
     CDS             1476..2357
                     /gene="truB"
                     /locus_tag="TU818_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL0924236.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTVVPLSLTEAMVD
                     EAMTQFIGQMTQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYIRTLAVDLGRMLGYASHMSWLVRTASSGLSLDQSYTLSEIA
                     ELLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLAAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            2371..3303
                     /locus_tag="TU818_001432"
     CDS             2371..3303
                     /locus_tag="TU818_001432"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL0924237.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLRHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRVRHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLITAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGKRYRSMTSIGKNITFGGKELRLEANIFDFNEDIYGETLEIIWLDR
                     IREMNKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            3346..3750
                     /locus_tag="TU818_001433"
     CDS             3346..3750
                     /locus_tag="TU818_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL0924238.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            3752..4030
                     /locus_tag="TU818_001434"
     CDS             3752..4030
                     /locus_tag="TU818_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL0924239.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            4020..4796
                     /locus_tag="TU818_001435"
     CDS             4020..4796
                     /locus_tag="TU818_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL0924240.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFSLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNDYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGKQPDFQSRQKVMFVPKSKLATIQSLLKTNENTQ"
     gene            4813..6120
                     /locus_tag="TU818_001436"
     CDS             4813..6120
                     /locus_tag="TU818_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL0924241.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQSV
                     CLDPPIPDTPWGYYGRVSGKSPNHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVIVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAVSYWHKDYPAACASLQRSILAEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSSYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DGLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLVINGNGLGFAKIVGRTLKNSFPKGLRF"
     gene            6258..7124
                     /locus_tag="TU818_001437"
     CDS             6258..7124
                     /locus_tag="TU818_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL0924242.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            7135..8070
                     /gene="pstC"
                     /locus_tag="TU818_001438"
     CDS             7135..8070
                     /gene="pstC"
                     /locus_tag="TU818_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL0924243.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILLF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPASLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            8060..8947
                     /gene="pstA"
                     /locus_tag="TU818_001439"
     CDS             8060..8947
                     /gene="pstA"
                     /locus_tag="TU818_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL0924244.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNVIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            8964..9767
                     /gene="pstB"
                     /locus_tag="TU818_001440"
     CDS             8964..9767
                     /gene="pstB"
                     /locus_tag="TU818_001440"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL0924245.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            9781..10539
                     /gene="pstB"
                     /locus_tag="TU818_001441"
     CDS             9781..10539
                     /gene="pstB"
                     /locus_tag="TU818_001441"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL0924246.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            10610..11263
                     /gene="phoU"
                     /locus_tag="TU818_001442"
     CDS             10610..11263
                     /gene="phoU"
                     /locus_tag="TU818_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL0924247.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINGFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            11497..14034
                     /locus_tag="TU818_001443"
     CDS             11497..14034
                     /locus_tag="TU818_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL0924248.1"
                     /translation="MKKVEHLIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQV
                     SFHQKDLAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIY
                     PSYYTKDGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMP
                     EVNAERRKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTS
                     LDFSLDIAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDG
                     NSTARSRQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIEPSWR
                     IFEDFQTTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRW
                     IGDKDFAAGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTAR
                     VDNDQLILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNK
                     GTLRFNTENTAHYITDYQGQLFHSLVDDLKHLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDKKSYMVAAAVQQVIRGLEQFIDEGTSAEQSFNRLISSIFQEDFRQLGFE
                     KRANESDEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQ
                     IKYFEIADLVDAYFDAYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQ
                     DLAAWYSFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLA
                     EYKAFFEPQLDDMAISRNISMGINEISARVALIDSEKEAIANALSQY"
     gene            14453..15127
                     /locus_tag="TU818_001444"
     CDS             14453..15127
                     /locus_tag="TU818_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0924249.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKEFDLLIY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKANE"
     gene            15120..16430
                     /locus_tag="TU818_001445"
     CDS             15120..16430
                     /locus_tag="TU818_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL0924250.1"
                     /translation="MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYS
                     TVDSSLISVGQNASNYANRTMARISSFYFDAENNLIQALPELEASKSLGSSTTNMDII
                     LFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
                     PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILDNSEHIASSLDEVRNMRILTTNL
                     LNLARSDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISVNQINRPLKTDKALLK
                     QLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVD
                     KARARQKGGFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL"
BASE COUNT         4936 a         3076 c         3760 g         4901 t
ORIGIN      
        1 aggggttagc tggtctttac ttgtttttaa gtgataaagt cgggagtctg gaaaaatcat
       61 tttctaggct ttttttgcta taatggcagt gagataattg caagaatgga gaaatcatga
      121 aagaactaaa atgtcctcat tgccatacct tatttacggt caatgagtct gactatagtc
      181 agattttagc acaggtacga ggtcaagagt ttgacaagga gttggcacag cgcttagaaa
      241 gtgagatgaa gctgcaagaa gcaagggcca ataaccgctt ccaagaggtg cttactaaaa
      301 aggagcaggc tattcaaagc ctgaccaacc gcttggagcg tattgagcag gaacaggcct
      361 atttgaggca acaggagcta gcccaaaagg ataaagagct cctagagctt cacaatcagc
      421 tagataagct agagcttgag cagcaatcaa ggctccagtc tgcccttaca gttgttgaaa
      481 aggaacgtga tcacctaaaa aatcagctcg tgctgcagga aaaagaaagc gaactttctc
      541 tagcctctgt gcgcagtgat tatgaggtgc agttaaaggc tgtcaatgag caggttgagt
      601 tttacaagaa ttttaaagcg cagcagtcaa ctaaagctat tggagagagc ttagagctgt
      661 atgccgaaac cgagtttaac aaggttcgca gctatgcctt tccaaatgcc agttttacca
      721 aggacaatca agtgtctcat cgaggctcaa agggtgatta tatttaccga gagctagaca
      781 ataatggtgt tgaaattctc tcaatcatgt ttgaaatgaa aaatgaggtt gacacgacca
      841 agaccaagca taaaaatagt gatttcttta aggaattaga taaggatcgc cgggaaaaga
      901 attgtgaata tgctgttctt gttaccatgc ttgaagcaga caatgattat tacaatgcag
      961 gaattgttga tgtcagtcat gactatgaca aaatgtatgt ggttcggcct cagctcttta
     1021 ttcatctcat cggattgctg cgtaacgctg ctcttaatag cttaaaatat aagcaagaac
     1081 tggcgcttgt cagggagcag cacattgata ttacacattt tgaggaggac ctagagcatt
     1141 ttaagcatgc ttttgctaaa aactaccagt ctgcaagcaa taactttaaa aaagccgttg
     1201 atgaaattga taagtccatc aagcgtatgg aggaggtcaa gcgctttcta acaactagcg
     1261 aaaatcagct gcgtttagcc aataacaagc tagatgatgt ctctgtcaaa aaactaacca
     1321 gaaataatcc aaccatgcgc gataagtttc aagcaatcaa gccctaggat tatctcagtc
     1381 aggcttattg atagaggctt tgttgcttgt caaaagcctt gtgaaatggt tataatagat
     1441 aggctaatga tcaaaacaat aaacgaaagt aacacatgat aaacggaata atcaatttaa
     1501 aaaaagaagc aggcatgaca tcacatgacg ctgtttttaa gcttagaaag ctattacaag
     1561 aaaaaaagat tgggcatgga gggacgcttg atcctgacgt ggtcggtgtt ttgcctatag
     1621 cagtggggaa ggcaacgcga gttattgaat acatgacaga agcaggtaaa acctatgagg
     1681 gagaggttac tcttggctat tcaacgacaa cagaggatgc tagtggagag attgttgacc
     1741 aaacagtagt gcccttgagt ttgactgaag cgatggttga tgaggcaatg acacaattta
     1801 ttggtcaaat gactcagatt ccaccgatgt attctgcggt taaggttaat gggcgcaagc
     1861 tttatgatta tgcacgagct ggtgaagcag tcgagcgccc taaaagacag gtaacgattg
     1921 accagtttga gcggacaagt cccttgacct ttgcaggtgg tctttgccga tttagcttta
     1981 gggtgagctg tagcaagggg acttatatta ggaccttggc ggttgatcta ggaagaatgc
     2041 ttggctatgc aagtcatatg tcttggctgg ttcggacagc ttcttcgggt ttaagtttgg
     2101 atcagtccta taccttgtca gagattgctg agctgctgga taaaaaggac atgagctttt
     2161 tattgcctat tgaatatggt gttagtgatt tagccagagt agtcgttaat gactgggagc
     2221 tgagagagct ttcctttggt agaaaaatcg ctctatcatg tgaggaaaat ctgttagcgg
     2281 ctttttatca ggacagcttg atcgctattt tagaaaagca agaagggctt tacaagccaa
     2341 gaaaggtttt tatttagaga agattgatat atggatatac aacacattaa aagctatcag
     2401 gagattgatg aatcagctga taccgtttta gtcttaggct actttgatgg tctgcaccga
     2461 ggtcacaagg ctctatttga taaggcaaag gaaatatcac gtcaggaaag cctaaaaata
     2521 gtcaccttga ccttccatga gtcccctcag ctggccttta cacgcttttc tcctgatttt
     2581 ttacgacaca ttacctatcc agaaaaaagg tatgaaaaat ttgctgagta tggtgttgat
     2641 aagctttatt tgcttgattt taccacgtca ttttcaaaac tatcctctga tgatttcatt
     2701 gaccactata ttgggcgttt aagggtaagg catatcgttg taggctttga ttatcacttt
     2761 gggtgtgatc acgcagatag tcattactta gctaaacgga taaaaggaac cgtttatagc
     2821 atttcagagg tcaaagaaga ccagatcaaa atctcatcaa cacgtatcag aagtctgatt
     2881 acagcaggag atgtcgctaa ggctaatcag ctgcttggct atgagctttc aacaagagga
     2941 atggttgtgc atggtgatgc gcgtgggcga accattggtt ttccgactgc caatcttgca
     3001 cctattgata ggacctatct gccagctgat ggtgtttacg tgacagatgt gctggttaga
     3061 ggaaagcgct atcggtctat gacgagtatc ggcaagaaca ttacctttgg tggtaaagag
     3121 ctgcgattag aggcaaatat ttttgatttt aatgaggaca tttatggaga aactcttgaa
     3181 attatttggc tagataggat tcgtgagatg aataaattta gtgatgttag cacctttatc
     3241 agccaactaa agcaggataa agaagctgcc ataaattgga aaaaagatag ccaaggctat
     3301 taaatttttg tataataagg taagcacaat taacagagga aaagtatgat taccttattt
     3361 ctatcaccaa gctgtactag ctgccgtaag gccagagcct ggctcaccaa gcatgacgtt
     3421 gactttcaag agcataatat tattaccagc ccacttagtc gtgaggagct gttagcgatc
     3481 ctatccttta ctgaaaatgg aacagaggat attatttcaa cacgatcaaa ggtttttcaa
     3541 aaattggata ttgatattga tgagctgtct atcatggatt tgattgattt gatcgcaaag
     3601 aaccctagcc ttcttcgtag gccaatcatt atggatagta agcgcatgca aattggcttt
     3661 aatgaagatg agattagggc atttttgcca agggattatc gtaagcaaga gctgcgccaa
     3721 gcaaccataa aggcagaaat cgagggataa catgtcagat cattatcatt acccacttga
     3781 tgtaagctgg agcactgaag agataacatc agtgcttcat tttttaaatc aggtagagtt
     3841 agcctatgag gctaaggtag gagcagagga gctactcaaa agctatgctg cctacaagga
     3901 gattgtaaga agcaaatcac aggaaaagca gattgaccgc gaattccaac aagccagtgg
     3961 ctattcaacc tatcaagctg tcaaaaaagc cagagaaatt gagaaaggat tcttttccct
     4021 tggaagataa atacgcattt gctaaaacga tcatcaaaga ggctggcctt ctgattaagg
     4081 atagaatgaa agatagctta gccattgaaa tcaagacgca gcatgatgat ttagtgacca
     4141 atgtagatca agagacgcag gatttcttaa ttgctaaaat caaacaggcc tatcctagtg
     4201 accatatgat tgctgaggag ggcggtatct gtcatgctat tacagatggc aaggtttggg
     4261 tgctggatcc tattgatggt acggtgaatt ttattgtaca gaaagccaat tttgcgatca
     4321 tgatggctta ttatgagaat ggcgtcggaa aatttagtct catttatgat gtcatggcag
     4381 atcagctttt ttcaggtgga ggagattttg ctgttacttt aaatgatcaa gtcctagcat
     4441 cttatcagga taagccgctt gatcgtagct taattggctg caatgcaggt atgctttcaa
     4501 ggaacgatta caacctgcac cagttgattg atcaaaccct aggagtgagg gtttatggcg
     4561 gtgcaggcat ttgcatgact aaggtgttaa ggcagcagct aatggcttat ttctcttata
     4621 ttcaaccttg ggattatgca gcggcagcca ttatgggcga aagccttggc tatgtcctgt
     4681 tgaccttgga gggaaagcag ccagactttc agtctagaca gaaggtgatg tttgttccca
     4741 agtctaaact agccaccatt caatctctgc tgaaaacaaa cgagaatacc caataagatt
     4801 aaaatgaaaa gcatgcaatt accaaacgat tttattgaaa aataccaaca gctgctaggt
     4861 tcagaagcaa aagctttttt tgagagcttt gatcagcctg ccatcagtgc ctacaggata
     4921 aatcccttaa agcaccaatc ggtctgcctt gatcctccta ttcctgatac accatggggt
     4981 tactacggca gggtatcagg aaagtctcct aaccacgtgt caggtgtggt gtattcccaa
     5041 gagcctgctg ctcaaatggt tgctcaggtg gcctcacctg ccaagggaac tagagtgttg
     5101 gatttggcag cagcgccagg tggcaagtca actcagttac ttgcctatct agagaataca
     5161 ggacttttag tgagtaatga gatttcgacc aaacgcagca aggccttagt tgaaaatata
     5221 gagcgctttg gtgctagaaa tgttattgtg acaaatgagt cagctgacag actggctgct
     5281 gtttttccag aatattttga cactattgtc tttgacgggc cttgctctgg tgagggcatg
     5341 tttcgcaagg atccaaatgc tgttagctat tggcacaagg attacccagc agcatgtgct
     5401 agcctgcaaa gatccatttt agcagaggcg atacctatgc taaagccagg tggtcagctg
     5461 atttattcga cctgcacctg gtcgcctgaa gaaaatgaag aggttgttcg ctggctacta
     5521 gaaagttatg attttcttga gctggagcat atccctaaga tcaatggtat ggcagagggg
     5581 atcggtatgc cacaggcagc tagaatgtac cctcatcgct ttaaaggaga gggacagttt
     5641 gttgctaagt taaaggatac tagatcaacg atttcctctt caagctacaa atctccaagg
     5701 tctaacctca ctcaagagca gctgaggctg tggcaggatt ttgaaaaaaa tcatttgaac
     5761 ataaccttgt ctggcctatt acaggtcttt ggtgatcgtt tgtacttgtt accagatggc
     5821 ttaccctgtc ttcgatcgct taaaatagca agaaatggtc tggaattagg cacttttaag
     5881 aaaaaacgct ttgagccttc ctatgctctg ggcttggcat taagacctga agaggtcagc
     5941 ttatctgttg agattaacga agaggacttt gtcacatacg cctcaggaaa taccattacc
     6001 ttaccagaat cttatgctac agattggtat cagctggtca ttaacggaaa tggtctgggc
     6061 tttgctaaaa tagttggtcg cacccttaaa aatagcttcc ctaagggctt acgtttttaa
     6121 ggaatggcat accattaaat ttttataaat ttaaataaaa cttcttccaa agcattgtta
     6181 gatatgttaa tataaagaat atgctgaagc ttaattcttc gctataaacc tttattttta
     6241 tgaataggaa tagaataatg aaatcgaaaa agaaattctt tttgttaagt cttttagcct
     6301 tgtcggcttt ctttttgtca gcctgctcaa gctggattga taagggagaa tccataacag
     6361 cggtaggctc aacagcatta cagcccttag tagaagccgc agctgatgag tttggaagca
     6421 ataacctcgg aaaatctgtt aatgttcaag gaggcggctc tggcactggc ttatcacagg
     6481 tgcagtcagg tgctgttcag gtaggcaata gtgatgtctt tgcagaagaa aaggacggga
     6541 ttgatgctgc taagcttgtt gatcaccagg ttgccgtagc aggacttgct gtcattgcca
     6601 atcctaaggt caaggtatct aatctcacaa gcaagcagct acaaaagatt ttctcaggtg
     6661 aatataccaa ctggaagcag gttggtggac aggatcttgc tatttcagtg attaatcgag
     6721 cggcaagctc aggctcacgt gctacctttg atagtgtcat catgaagggt gttactgcta
     6781 agcaaagtca agagcaggat tctaacggta tggttaaatc aattgtgtct cagacaccgg
     6841 gggccatttc ttacttatcc tttgcctatg tggattcgtc tgtaaaatca ttacgattga
     6901 atggctttaa ggccaatgcc aaaaatgtag caaccaatga ttggcccatc tggtcctatg
     6961 agcatatgta taccaaaggc aagccagacg gcttaaccaa ggaatttttg gattatgtgc
     7021 tatcagatga ggtccaaaaa accattgtga cacatatggg ttatattgct atcactgata
     7081 tgaaggtcgt caaatcctat gatggaaaag ttacagataa ataatggggg aattatgaaa
     7141 aatcaggaat tagctaagca attagcctca ccatcaaaaa attcacgact tgaagcattt
     7201 ggtcgtacga ttaccttttt ttgcctcgcc ttaattgttt ttatcgttgc aatgatttta
     7261 ctttttgtgg ctcaaaaggg cttgtctacc ttttttgtaa acaaggttaa tctttttgat
     7321 ttcctatttg gtacagagtg gcagcctagc gttaaaaatg ctgccggtgt tccttatctt
     7381 ggagctcttc cgatgattgc tggatcgttt ttagtcacga ttttatcagc cttggtggca
     7441 acaccatttg ccattggggc agcagtattt atgactgaaa tttcacccaa gtacggggca
     7501 aaactattac agccagcagt tgaattgctt gtaggtatcc cgtcagttgt ttatggcttt
     7561 attggcttgc aggttgttgt tccttttatt cgttctattt ttggtggaac aggctttggt
     7621 atcctatcag gggtctgtgt cttgtttgtc atgattttac cgacggttac ctttatgaca
     7681 acagatagtc tgcgcgctgt tcctcgtcat tatcgtgagg cttctatggc tatgggggct
     7741 acacgttggc aaaccatttg gcgagtggtt ttaaatgcgg ctcgtcctgg tatttttact
     7801 gctgttattt ttggtatggc tagagccttt ggtgaggcct tagccattca aatggttgtg
     7861 ggaaattcag cagtcatgcc ggcttcacta accactccag cggctacatt gacctctgta
     7921 ttgactatgg gaattggtaa tacagttatg ggaactgttc aaaataatgt gctatggtca
     7981 ttagcccttg tcttattgct gatgagtcta gcttttaatt cccttgtcaa attaattacg
     8041 aaagagagaa agagaaatta tgaacgctaa aaaggttgat aaagtagcaa ctggtagctt
     8101 gtatactatt gctggaatta ttgtagctat tttagcttcc ctaattctgt ttattcttgt
     8161 gcgtggccta cctcacatca gctggtcgtt tttaacaggg aaatcatcgt cctatgaagc
     8221 tggtggaggt attgggattc agctttataa ttcatttttc ttgctggtag taaccttgat
     8281 tatttccatt cccctatcaa caggtgctgg catttatttg gccgaatacg ctaaaaaagg
     8341 acctgtgaca aatgtgatta gaacctgtat tgaaatccta tcctcattgc catctgttgt
     8401 ggttggattg tttggctacc ttatttttgt tgtacagttt gaatatggct tttctattat
     8461 atcaggtgcc cttgctttga cggtatttaa tcttccgcaa atgacaagaa acgttgagga
     8521 tagcttgctg catgtgcatc atactcaaag agaggcaggg ctagcccttg ggctttcacg
     8581 ctgggaaacg gtttttcatg tggttattcc agaggccttg ccaagtattg tgacaggtat
     8641 tgttttggct tcaggtcgta tctttggtga agcagctgct cttatctata ctgcgggtca
     8701 gtctgcccca gcgcttgatt ggtcaaattg gaaccctttg agcgtgacaa gccctatttc
     8761 aattttccgt caatctgaaa ccctagctgt tcatatttgg aaggtcaata gtgaagggac
     8821 aatccctgat gcaacacttg tttctgctgg tagtgcagcg gtgttgttga tttttatcct
     8881 tattttcaat ctatcagctc gctttattgg caagcgtatt catgctaaga tgacagcagc
     8941 aaaataagac attggagaga ttcatgacag aatataattg gaacgaacgt catatcatta
     9001 catttccaga agaaacgatt gccctagcta ctaaggatct gcatgtttat tatggtagca
     9061 aggaggcaat caaggggatt gatatgcaat tcgaaaaaaa taaaattaca gccctaattg
     9121 gaccctcagg ctgtggcaag tcaacctatc tgcgcagcct caatcgcatg aatgacacca
     9181 ttgatattgc tagagtaaca ggtgaaattt tgtatcaagg cattgatgtc aatcgaaagg
     9241 acatgaatgt gtatgaaatc cgtaagcacc taggaatggt ctttcaaagg ccaaatccat
     9301 ttgccaagtc tatttataaa aacatcacct ttgctcatga aagagcagga gtgagagata
     9361 aaagggtttt agatgagatt gtcgaaacct ccctcaagca ggctgcacta tgggatcagg
     9421 tcaaggacga tcttcataaa tcagccttta ccctttcagg aggtcagcag cagcgcttgt
     9481 gtattgctag ggctatttcg gttaagccgg atatcttgtt gatggacgaa ccagcttcag
     9541 cccttgatcc tattgcaacc atgcagctag aagaaaccat gtttgagttg aagaaggatt
     9601 acaccattat tatcgttact cataacatgc agcaggccgc tagagcaagt gattacactg
     9661 ctttcttcta tttgggtgac ttaattgaat acgataaaac gcgtaacatt ttccaaaacg
     9721 ctacctgtca gtccacaaat gattacgtct cagggcactt tggttagaaa gaaggatatg
     9781 atggcagaac ctattttaca aatcagagat ctttctgttt actataataa aaagaaaacc
     9841 ttaaaggacg tgtccttaga tttttaccca aatgaaatca cagcactcat tggcccttca
     9901 gggtctggga aatcaacact tttgcgttcc atcaatcgca tgaatgacct gaatccagag
     9961 gtaaccatta cggggtcaat cgtttataat ggacataaca tttacagtcc aagaacagac
    10021 actgttgatt tgcgaaaaga aattggtatg gtctttcagc agcccaatcc ctttccaatg
    10081 tctatctatg aaaacgttgt ctatggcttg cgcctaaagg gcattagaga taaggctgtt
    10141 ttagatcacg ctgttgaatc ctctctcaaa ggagcctcca tctggagtga ggtcaaggat
    10201 aggcttcatg attcagctgt tggactatca ggaggtcaac agcagcgtgt ctgcatagca
    10261 agggttctgg caaccagccc taaaatcatt ttgttagatg agccaacatc ggctttagat
    10321 cccatttcag ccggcaaaat cgaagagacc ctgttctcac taaaaaagga ttatacgatg
    10381 gttatcgtta cccgctccat gcagcaggcc tcgcgcttgt cagaccggac aggcttcttc
    10441 ttagagggag accttcttga gtttggtcct actaaggcaa tgtttatgaa ccctaagagg
    10501 aaggaaacag aagattatat ttcgggtaaa tttggctaag ggatcttgtt tgtagtctag
    10561 gtatccgctc tgtttaggat aataaatgaa tcaatagaaa gaaaaaatga tgttaagaac
    10621 taaatttgaa gaagaattag acaagctaca caatcagttt tactctatgg gaacagaagt
    10681 cttgtctcaa atcaataaaa ccgttcgtgc ctttgtcagt catgaccgcg aattggccaa
    10741 agaggtgatt gaggaagacg ataccatcaa tggatttgaa acaaaattag aaaaaaagtc
    10801 tcttgaaatt atcgccttac agcagcctgt ttcaaacgat ttgcgaacag ttattactgt
    10861 tttgaaggcc tcaagtgata ttgagcgtat gggagatcac gctgcctcta tcgctaaagc
    10921 aaccattcgc atgaaaggag aagagcgtat cccgattgtt gaggagcata tcaacttgat
    10981 ggggaaggca gtcaagcaga tggttgaaga ggcgctaaat gcttatatta atgcagatga
    11041 tgccaaggcc tatgaaattg ctgcttcaga cgaaatcatt gataattatt tccgcgaaat
    11101 ccaatctcta gctgtcgaag aaattcgcaa gacaccagat gccgtctttg ctggcaagga
    11161 atacttccag gttctcatgt atttagagcg tatcggtgac tatgctcgta atatttgtga
    11221 atggattgtc tatttaaaaa ctggaaaaat tattgaatta taagaaagta tggtataatg
    11281 ggggctgggt gaacttctca gttcctcgtt ttattatagc gattaaaagg ttttagaggc
    11341 tggagcttca gctgagctga ctatcagctg tcaagcttct agacaaaatg aaagataaca
    11401 ataagctagt cgtctaaggg actagacggc aggattgatt atattaagaa tgtgaccttg
    11461 tcccatcact aatttaatga catattaagg agttgtatga aaaaagtaga acatcttatt
    11521 gaaaagttta ttcctgaaaa ttataatatt ttcttagaca ttaatcgcag cacaaaaacc
    11581 ttcacaggta atgttgcaat caatggtgaa gcattagata atcaagtgtc atttcaccaa
    11641 aaggacttgg caatcaatgc cattttactt gacaatgaag ctgttagcta tcatgttgac
    11701 gatgacaatg agcttgtgcg tgttgagctg ccagagactg gtatgatgac gcttgtcatt
    11761 gaattttcag gtaatattac tgacaatatg actggtattt acccgtccta ttacacaaaa
    11821 gatggtgaaa aacaggaggt tatttcaacg cagtttgaaa gccattttgc gcgtgaggcc
    11881 tttccatgta ttgacgagcc tgaagcaaag gctacctttg acttaagctt gacatttgac
    11941 caagcagagg gcgagattgc tctatcaaat atgcctgagg tcaatgctga gcgccgcaag
    12001 gagaccggtc tttggacctt tgagacaact cctagaatgt cttcttatct gctggccttt
    12061 gccttaggag acttgcatgg caaaacaaca aaaagtaaaa acgggacaac agttggtgtt
    12121 tatgcaacca aggctcaccc actgacctcg ctagattttt cattggatat tgctgtacgt
    12181 gtcattgatt tttacgaaga ctactttggg gttcgctatc ctattccgca atctctaaat
    12241 attgctcttc ctgatttttc atctggagcg atggaaaact ggggcttgat tacctatcgt
    12301 gaaatttacc tgttggttga tggcaattca acagcccgca gcagacaaaa tgttgctctt
    12361 gttgtggcac acgagattgc ccatcaatgg tttggtaatc ttgtaaccat gaaatggtgg
    12421 gacgatcttt ggctaaatga aagctttgcc aatatgatgg aatatgtagc catcaatgct
    12481 attgagccgt catggcgtat ttttgaggat ttccaaacaa caggtgtgcc gctggctctt
    12541 aagcgtgatg caacagacgg tgttcaatca gtccatgttg ctgttaatca cccagatgag
    12601 attaataccc tgtttgatcc agctattgtc tatgccaaag gtagccgctt aatgcatatg
    12661 cttcgtcgct ggattggcga taaggatttt gcggcaggtc tgcgccttta ctttgaaaag
    12721 catcaatacc gtaatactgt aggacgtgat ttgtggcagg ctctttcaga agcttctggt
    12781 aaagatgttg ctgcgtttat ggacgcttgg ctagagcagc caggctatcc tgtcttaacg
    12841 gccagagttg acaatgatca gttgattctc agccaaaagc agttctttat tggtgaggca
    12901 agcgaccaaa agagactatg gccaattcca ctaaatgcga actggaaagg tcttcctgac
    12961 gtactgacag aggagtccat cgttatttca ggctttagtc aattagccgc ccaaaataaa
    13021 ggaacacttc gctttaatac agaaaataca gcgcattaca ttacagatta tcagggacag
    13081 ctctttcata gcttagttga tgatttgaag catcttgaca acacctctgc ccttcaagtg
    13141 attcaagagc gccgcttgct ggctgatagc ggtctgattt cttatgcaga gctggttgac
    13201 ttaatcgctc agctagatga caaaaaatcc tatatggttg ctgcagctgt tcagcaggtt
    13261 attagaggct tagagcagtt cattgatgaa ggaacctcag cagagcagtc cttcaatcga
    13321 ttgatttctt ctattttcca agaggacttc aggcagcttg gatttgaaaa gagggcaaat
    13381 gaatctgatg aagatgaaat ggttcgtcaa attgctttac atcacctgtt ggttggaggc
    13441 aatcgtgatg tgatcaagca ggccaagact atctttgaag cttatgcaaa tcgtatcgaa
    13501 gccattccag cagccattcg ccgctcggta ttggtgagtc agatcaagta ttttgaaata
    13561 gctgacttgg ttgatgctta ttttgatgct tatgttgcaa ccaaggacaa caatcttcga
    13621 gctgatttga gcgccgcctt agcaacaaca gctaatccat caactcttaa gcgcattcag
    13681 tacagcttaa aggataagga tattattaag ccacaggact tagcagcttg gtacagcttt
    13741 ttgcttgatc aggcctctgc acaagaaagc atttggcgtt gggctagaga aaattggaag
    13801 tggattaagg cttcactggg tggtgatatg agctttgaca agtttattat ttaccctgct
    13861 aaccatttta aaacagcaga gcgtttagct gaatataagg ccttctttga gccacagctt
    13921 gatgatatgg cgattagtcg caatatttcg atggggataa atgaaatttc agctcgagtt
    13981 gccctcattg atagtgaaaa ggaagctatc gctaatgctt taagtcagta ctaatgatat
    14041 cacaaaggag ctggggacca tcctcaactc ctttattggt gtcaaagcta ctatctttaa
    14101 gtaacattta gatcaaaggg taattgctgt agcttagtgg cactgcctgt cagcttttgg
    14161 caaatgagga ggcttcaatc ataagcagtg gttaatctta gcgccgtaaa ttactagttg
    14221 atcagagtca gagcttagga cggataggtc atagagacaa ttctttgtct gtcagtttta
    14281 taacttaagt aggtctccag actaactgta tgcttatgac ctgtcatgag caatagttta
    14341 gcaaagctta agctttttgt gttatcgtta gattagagaa ttcatttagt aaggtaatcc
    14401 ctaaagacta cttgagcgag gctgttagtc tttagagaat tgaggtatca taatgataaa
    14461 actattatta gtagaagacg atttaagctt gtcaaattct atctttgatt ttttagatga
    14521 ctttgctgat gtgacgcagg tttttgatgg tgacgaagga ctctatgagg cagaaagcgg
    14581 tatttatgat ttgattctgt tagatttgat gctgcctgaa aaggatggct ttcaagtgtt
    14641 aaaagcctta cgtgaaaaag acatcaaaat tcccgtcttg atcatgactg ccaaagaaag
    14701 catcgatgac aaagggcatg gctttgagct tggtgctgat gactatttaa ccaagccctt
    14761 ttacctagaa gaattaaaaa tgcggattca ggccttgctt aagcgcgtag gaaagtttaa
    14821 tgacaagagc cttaaatttg gcaacctgac tgtagatact acccgtaaag aggtacaggt
    14881 caatgggcag gccatagagc tattaggcaa ggagtttgat ttactaatct atatccttca
    14941 aaatcaaaat gttattttgc caaaatcaca aatttttgat cgtatctggg gctttgatag
    15001 tgataccact atctctgttg tagaggtcta tgtctctaaa attcgtaaga agcttaaggg
    15061 gacagacttt gttaatcatc ttcaaacctt gagaagtgta ggatatatct taaaagctaa
    15121 tgaataaact aaaaaaagga ttattgtccg ataattatac gcattttttt catttctttg
    15181 ctatttttac aggcattttt gttgtcatga ccatcattat tttacaaatc atgaggttta
    15241 gtgtctattc cacagtagac agcagtctca tttcggtcgg tcaaaatgcc agcaactatg
    15301 ctaataggac catggcgaga atatcttcct tttattttga tgcagaaaat aaccttattc
    15361 aggctcttcc tgaactggaa gcgtcaaaat cacttggctc ctccaccact aatatggata
    15421 ttattttatt tagtgctaat gggacgatat tgaactcctt tgacgctttc tctaattacc
    15481 aaagctttcg tttagacaaa agccagctca ataacattgt caccacacag ctgatgaatt
    15541 tttatgggca aaaggagaaa taccataccc taaccgttaa ggttcacatt aaaaactatc
    15601 cagcagtggc ttatatgatg gcagtggtta atgttcagca gctggatact gctaatgagc
    15661 gctatgaaca gattattatc atggttatga ttgtcttttg gttaatttcg attttggcca
    15721 gtatttattt ggctaagtgg agcagaaagc caattatgga gagctatgcc aagcaaaaaa
    15781 tgtttgtaga aaatgccagt catgagctta ggactccttt agcggtgctg caaaatcgtt
    15841 tggaatcgct gtttagaaag cctaacgaaa ccattttaga caatagcgag catattgcgt
    15901 caagcctaga tgaggttcgt aatatgagaa tattaacaac taatctgtta aatttagcca
    15961 gaagtgatga tgggatcaag ccgcagctag ttgatgttga tgcagccttt tttgatactg
    16021 tttttgaaaa ttatcaatta gttgcagaag agtcaggcaa gcagtttatc tcagttaatc
    16081 agatcaatag gcccttaaag acggataagg ctttgctcaa gcagctgatg accattttgt
    16141 ttgataatgc gatcaaatac actgatcata acggtgtggt tgaggtcaag gttagaacga
    16201 ccgataagca tttattgatt tctgttattg ataatggccc agggatcaag gatgatgata
    16261 agaaaaagat ttttgatcgc ttttaccgag tggataaggc aagggcacgc caaaaaggag
    16321 ggtttggact cggattggcc ttagcgcagc agatcgttac ctcattaaaa ggaacgatta
    16381 ccgtcagtga taataagcct accggcgcca tctttgaagt aaaattatag cactgagttc
    16441 ttgctagccc ataatcagta tgaaaataac agtcactaga tcaagaagtc tagtgacttt
    16501 ttttattgtc ttctttttgc tgttgaccaa gcagttgaca agaaaattcc aatagatagt
    16561 ttaaagccaa taaaaccatt attaggcttg cattacaggc aggtatcaaa caaagatata
    16621 gaaaaatata ccataaaaaa tctcataaaa gtgtcaaaat ggtaaaaaat tgc
//
LOCUS       DARYMD010000042        16646 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYMD010000042 DARYMD010000000
VERSION     DARYMD010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16646
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            104..313
                     /locus_tag="TU818_001446"
     CDS             104..313
                     /locus_tag="TU818_001446"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924251.1"
                     /translation="MTQVRVYLWLSCDDGDNIESNSMTSRKPLAKEDIKKVIVACLSF
                     SEVGYRLKEKGLGIRVSFWLLKSVI"
     gene            458..934
                     /locus_tag="TU818_001447"
     CDS             458..934
                     /locus_tag="TU818_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0924252.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNDETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(1097..2299)
                     /locus_tag="TU818_001448"
     CDS             complement(1097..2299)
                     /locus_tag="TU818_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL0924253.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQIDPSISSYYKADYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
                     NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYERQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
     gene            2479..3378
                     /locus_tag="TU818_001449"
     CDS             2479..3378
                     /locus_tag="TU818_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL0924254.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KHYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALVMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
     gene            3402..3719
                     /locus_tag="TU818_001450"
     CDS             3402..3719
                     /locus_tag="TU818_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0924255.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLEADIFALPLTEA
                     EDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            3729..4061
                     /locus_tag="TU818_001451"
     CDS             3729..4061
                     /locus_tag="TU818_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL0924256.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADKALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            4054..5370
                     /locus_tag="TU818_001452"
     CDS             4054..5370
                     /locus_tag="TU818_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0924257.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEAWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVSFVNESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYADPGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTKNEG"
     gene            5435..6782
                     /locus_tag="TU818_001453"
                     /pseudo
     CDS             5435..6782
                     /locus_tag="TU818_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            6955..11595
                     /locus_tag="TU818_001454"
     CDS             6955..11595
                     /locus_tag="TU818_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL0924258.1"
                     /translation="MLFNPIGKEQIRKYAIKKLSVGVASVCVGIGLAAGLPVAVYADD
                     VSEVSLQQPTKAAVTEISHEQEPQATDTDSEALVVSEETTVDEAVVANAVTSNAADQT
                     ADEEKSNAPIELNKVANGGFDNDYVSNKNQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEADTPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKLSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWQDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLDNGNLVLNVTERYGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYIKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDDRLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSVENEYLFTNKGGNTNAALQAAGRDDLSA
                     LSELAPGIYNIYYSAVPYNADLGSTVTPTAKIAREVAILTVLPKEGLIGKKGEPLSTV
                     ALPANWQWVTPEEILGSAEHYQIKYTTEGGRAVYTSIEASYISDQPISDQASILVDLG
                     NAILDATAEKAAVTDDEALGKLDDVMNLTQGTVTIRYRLDTADTTVRSSSPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTLTIGGLKRTYDGESVLHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLIAAADA
                     RKKHYNDWGDVATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQSGHQTDMYVDEGNFETAFSTRGNLYQTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGMTWDDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSIHWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEEVTITSAAPKQNGKVSITIQMTFNQPMFILGDRQLAVTVNGVDKLASYVSGDGT
                     DTAIFELSLESMPEGPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPAAVTA"
     gene            11756..13555
                     /locus_tag="TU818_001455"
     CDS             11756..13555
                     /locus_tag="TU818_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL0924259.1"
                     /translation="MERFQISDQFYLDGRSLQILSGAIHYFRIHPDDWYHSLYNLKAL
                     GFNTVETYVPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWEFG
                     GLPAWLLTKNCHIRSSDPVYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYGSY
                     GEDKAYLTAVKGFMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQENFA
                     DMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEERADAVMEVLAQGSINLYMF
                     HGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAELSEIEV
                     TPPLIKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTHLL
                     KDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIENMG
                     RVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPGFY
                     HYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLNDIV
                     IFETEGVYQDSIRLVDRPISIDYPQADDRTDQT"
     gene            13970..14791
                     /gene="mutM"
                     /locus_tag="TU818_001456"
     CDS             13970..14791
                     /gene="mutM"
                     /locus_tag="TU818_001456"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL0924260.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVRVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDFGQLVMISHLRMEGKYLLFPDTVPEHKHFHVFLTMTDGS
                     TLVYQDVRKFGTFDLLPKAELAAFFQKRQLGPEPTKQTFQLKTFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAARVHPERRSASLKKAEIKRIHDETIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGTSIVKLKVGGRGTHVCPRCQKQ"
     gene            14788..15381
                     /locus_tag="TU818_001457"
     CDS             14788..15381
                     /locus_tag="TU818_001457"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL0924261.1"
                     /translation="MTKVIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQKKGG
                     KLYQVLLETFGQDILLPSGQLDRPKLAELLFAHSENMAKSSQQQNAIIREALAKQKEE
                     LSQTEAIFFMDLPLLVELGYQDWFDAIWLLYVDEETQLKRLMKRNQLTELAARQRIAS
                     QLPMSQKRAYADLVIDNTGDFQALETQISKALHDLEA"
     gene            complement(15544..16584)
                     /locus_tag="TU818_001458"
                     /pseudo
     CDS             complement(15544..16584)
                     /locus_tag="TU818_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677601.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
BASE COUNT         4449 a         3054 c         4100 g         5043 t
ORIGIN      
        1 ttataaaggg tattttattt aaagattttg aaggaaaaaa acacctatag gtacaatcaa
       61 tcaaaaaaac agtaggtacc tactactgat tgaggagaag gcaatgacac aagtacgtgt
      121 ttatttgtgg ttatcatgtg atgatgggga taatattgaa agtaattcaa tgaccagtcg
      181 caaaccattg gccaaagaag acattaaaaa agttatcgta gcttgtctga gtttttctga
      241 ggttggttat agattgaaag aaaagggact tggcattcga gtctctttct ggcttttaaa
      301 aagtgtgata taatcaggtt gaaaaattag ggctatatgc tttgccagcc tatcaaggac
      361 aagagacaaa gcctgcattg cttattggtt ggcaaaaaag cagcaattgc gccagctgac
      421 tggctttaat cttatgatgg caatgaaggg agttacgatg acacaggact atatttccta
      481 tattcgctca aaggtggggc atgataacat tattctgact tttgctggtg gtattttggc
      541 caatgccgaa ggtaaggtgc ttttgcagct acgtgcagat aagaaaacct gggcaattcc
      601 gggaggtgcc atggagctgg gtgagtcttc tgctgaaacc tgcaggcgtg aattttatga
      661 ggagacgggg attacagtag agcctttacg gttgttgaat gtttatacca attttgaaga
      721 gacctatcca aatggtgata aggttcagac cgttgtgatg ctttatgagg ttatagccaa
      781 ggcagataag gctatcactg attatcaaaa tgatgaaacc ttaaggctcg gttatttttc
      841 tagagaagag attgcagagc tgtcttcaat ctcagacaag catagactga tgctggcaga
      901 gtattttgct ggtgagtttc aaatggggca ttaggataga acagagagaa ccaagtgcct
      961 ctcttttttt atggttatca tttgtctcgc acctgcggag cgagatggac tgaaagtcgc
     1021 ataatgcaaa agcccacttg agaaatagct tctcaaatgg gctttaaagc tttagctgat
     1081 attggtgtgg gggttatcaa tcatatttgt ttttataatt gaggtaaagc tcatctatac
     1141 ataagcctgt agctcccaca gcggcattat agacagaaaa aggcatgaca atgatttctg
     1201 gctttttttg attgctaaga agcttaatgt cattttgcag ggcttgcaga attttggagg
     1261 atataagagg atggctgata aatctgccat ggagatagat ttgctcggta tcaatcagta
     1321 aggagaggtt agacagggat aaaacaaggt aatcaatagc tgtgtgaatg agcgtggtca
     1381 ccccgacatc accaagctca taggcaatca agagatggtc tagcttgagc tcacaggcct
     1441 tatcgacaag gcttcttaga tgagaattgg gggcatactg atgtagcagt tttgcttttt
     1501 tgagcaacca ggcattgctg gcataggtct gtaaacagcc ttttttgcca cattcacaaa
     1561 gctctccagt ggggttgaca atggtatgtc cgatttcccc aacaacagca ttgtgacggc
     1621 tataaatgac ccccttatac atataggagc agtgcatgcc tcgtccgaca tgaaagaaaa
     1681 taaaattgtg attatgtgcc tgacgctcgt ataagcgctt ggcaataatc atacagtgag
     1741 cattgttgct aaagaccact ggaataggga aggacttcgc aattgcggtt aaatcgacct
     1801 gctgccagat gggattgttg gtgttaatat gcgttgagct ggaggtggaa tgatcgtaat
     1861 gcccaggcag tgctattcct atggcttgta catcatagtg cttgtgctgc ttgaggaagg
     1921 cttgaatcag ctcagagata tagtctgctt tgtagtagga ggaaatgctt gggtcgatct
     1981 gttggttgtg cttggcatag atggtgccca ggttatctgt aatgaccaaa tagaaatgct
     2041 tttcggacaa ttcgacacca gcaaaataaa aggcgttagc cgaagcatca agtaatattt
     2101 ttttgcggcc aacggagtgg tccgtcagct ctccgatttc gtgtatccac ccctgtgcta
     2161 gcagctcttt agtgatagcc cctactgtag caggtgtgat gtgcgttagc tttgaaatat
     2221 caatgcgtga aataggccgt tgggcataaa tggtatctaa aatttttgcg taaagctctt
     2281 gttgtttatc cgtcttcata gtaacctcta ttatcgtacc tctatcatac caaaaaagaa
     2341 ttaaaaatcc tgcctgaaaa cgttgacaaa tattggtaaa tagaatatac tttatttgtt
     2401 tataaaaagt aaacaaataa gagttaaatc ttatttatct tttgttaatg tttttaaaat
     2461 aaaaataaag gagaagcgat gaaaacacga ttattgagtg ctagtagctc agaaatgcta
     2521 cagttaacat cgttagagct aaagcaagcc attaaggcaa gcgagggacg taccattgtc
     2581 tcagaaaatg tagcgccaag accctcttgg actggagatg accttacgaa cgctgaggtt
     2641 gccgcagcct ttagtgctga tttgattttg ctgaattgtg tagatgtctt tgatgttcaa
     2701 atatctggtc tacctgctac tgatcagcct attttagagc tgcgtcgtct ggtggggcgt
     2761 ccaattggtg ttaatttaga accaattgat ttggacgttg acatgactga aaagcgcttg
     2821 gagctagtag aagggcgaca ggcgacagct aagacctttc aagagattga agccttgggc
     2881 tttgactttg tttgcttgac aggaaatcca ggtactggtg ttagcaataa tcagattgaa
     2941 agagctattc aacaggccaa gcactatttt tcaggcttga ttattgctgg aaagatgcat
     3001 gctgctggct ctaatgaagc ggtgattgac ttagaaactg ttcggcggtt tatcgaggct
     3061 ggggctgatg tgattttagt tcctgctgtt gggacagttc ctggctttac agagggtgac
     3121 cttagagcta ttgttgagga ggtgcatgct cacgatgctc tagttatgtc agctattgga
     3181 acgagtcagg aagggtcaga tactacgatc gttcgagaca ttgctattcg caataaaatc
     3241 tgtggtgtcg atattcatca tatcggagat gctggctata gcgggattgc gccagtggaa
     3301 aatatctttg ctcttagtga cgctatccga ggaaaaagac ataccattgt gagaatgtcg
     3361 cgctctattc gacgttagga tttgggataa aggagaagat catgagtaaa aaacaaatta
     3421 tgttggcctg tgcagcgggt atgagtacca gtctattagt gacaaagatg gaaaaggctg
     3481 ctgacaatcg ggggcttgag gcagatattt ttgcattgcc attgactgag gcagaggatt
     3541 acgctctaag ccatcctgtt gatgtggtgt tattagggcc acaggttgct tatcaattgt
     3601 cagcatttca agaaagcttg gcagaaaagg acattccagt ggcggttgtg ccaatggttg
     3661 attacggtat gatgaatggt gataaggtta ttgccttagc tgaaagtttg atgaaatagg
     3721 tggtggtcat ggaagataag cagctagaga cgattatggg cctgatcatg catggtggta
     3781 gtgccaagtc gcttgcgatg gaggcgattg cttttgctaa aaagggagag ctcaatcaag
     3841 ctcaggaaag tctaaagcag gccgataagg cattggtgca ggcccatcat gcacaaacag
     3901 atatgctaac tcaagaggca cggggaaatg ctacaccagt aagcctacta ttagttcatg
     3961 gtcaggatca tttgatgact agtattacct ttgttgattt ggcaagggag ctagtatcta
     4021 tttatgaaag gttaacgtca caaggaggta acaatgacta aatttgaaga ttttatccag
     4081 caaaagcttg ttccagttgc tggtcgccta ggaagcaatc gctttcttat tgctattcgt
     4141 gatgggatca cctacgctat gcccttgatt ttgattgggt cctttttaat ggtgattgct
     4201 agcctgccga ttcctggttg ggaagcttgg cttggtgaga ttggtgtctc tacctatctg
     4261 tggaagggag tagattcgag ctttaatctg attgccttgg ttgcggcctt tgggatttct
     4321 tatagcttgg ctaagcagta taaggcagac gggatttctg ctgggattat taatatctct
     4381 gcctttttaa cagtgacccc atttactgtt tcatttgtca atgaatctgg taaagccttg
     4441 ggtgaggtag cgggtattgc gccttcttac ctttcatcag gcggcttgtt tgttgccatt
     4501 gttttgggat tggtaaatgg ctatgcttat caatggttta tgaaaaagga tattcggatt
     4561 aagatgcctg agggtgtgcc gcctgcagta tcaaaaagct ttagcgccat tattcctgga
     4621 gcggtgatta ttgtgttttg gcttgctgtt tatgctttct tggatcattt tagcctgcca
     4681 aatgtccatg acattgttaa gtccgtacta ggagttccat ttggcttgct gggaagtacc
     4741 ttatttggta attttatcgt tgttcttctt aatggctttt tatggttctg tggtgtgcat
     4801 ggtggaaatg tcctaaacaa tcctattatg aagccgatct ggttatctaa cttgactgaa
     4861 aatatggcag ctcataaggc tggtcaggaa ttgccgcatg tctttacgtc tgtctttatg
     4921 gataactttg tttttatcgg cggagctggt gcaaccattg gcttggtgtt ggctttagcc
     4981 tggttagcac gtcgtcgcaa ggctagtcag caggcaaagg tcttgtcacc attgaccttg
     5041 attccagggt ttttcaacat taacgagccg accatgtttg gcttaccggt tgttttaaat
     5101 ctattgacag ttattccttt tgtactagca cctgttatga atttgtttgt cgcttatttt
     5161 gcctttgctt ctggcattgt acctggcacc tatgctgatc cggggtggac catgccgcct
     5221 gttatttcag gatttttggc aacgggcagc tggcaagcct cagtcctaca gcttgtttta
     5281 attattctag atattcttct ttacttgccg tttattatta atgtggaaag aagatggcag
     5341 gcgagcgagc aaactaaaaa tgaaggctaa gctgttagag agagccttta ctgctctatc
     5401 ttagctgttt tatgattgtt ttaaggagct atgaatgaat aactatatga actttctttc
     5461 gcaaaagctg ctgccaattg ctacgaagat tggtaatcaa cgatttttag tggccttgcg
     5521 agattctttt attgcaacga tgccggttgt gatgacaggc tctattgccc tgttgatcaa
     5581 tgccttttta gtggatattc cagaccaatt tggcttgcaa ggcattacag aggccttcca
     5641 atggtgggta accatcaaca accttgtctt taagggaagc atttcgattg tgtccttgct
     5701 atttgtgtat tgcttagggg ttaatgtcgc taaactttat aagacagata cgctctcatc
     5761 aggtttggtt tctttagctg cctttgtgat tgcgattggg gattctgtta cctctagcat
     5821 tgacgcgtca ggtctcaagg gtgttgatct tgtgacggct tttaaggaca gtggtgttac
     5881 tgtcagcggc agctcactta atgtgaccat ctcaggccta ttgcctggtg cgcaaattaa
     5941 ctccaatggt tattttacag caattatgat tggcttttta gcctctatta ttttttgtaa
     6001 attaatgtta aaaaattgga caattaaatt accagatagt gtgccacctg ctgtagccaa
     6061 gcccttctta tctatcatac caggcttttg cgccttgtat agcgtagcta ttttaacatt
     6121 tgtctttgaa aagctaacgg gttctttgat gattgattgg atctataagg tcttgcaaat
     6181 cccacttttg ggcttatcac aaagctttat tgctgttgtt ttggtagctg ttttgaccca
     6241 atttttctgg ttctttggga ttcatggcgg caatgttatg gcgccaaata tggagggagt
     6301 atttggtgtt gccctcttgg ctaatttgga ggcttatcaa aagcatgagg cgattcctta
     6361 tctttggacg agtgttcttt gtatggtatg caaccttagg gctcttgatt gctattttct
     6421 ggaagtctaa aaatgaacac tatcgtgagg tggctaagct aggtgttgct cctgtattgt
     6481 ttaatatagg agagccagtg atgtatggtt taccaactgt tttaaatcct ttgttgttta
     6541 ttccgtttat tgtttgtcct gctgttatgt caagtgttgc ttatatcgca actagtctgg
     6601 gcttggttgc acccgttacg caaaatgtga cctgggtaat gccgcctgtc ttgtatggct
     6661 tcttttcaac tggttttgat tggcgtgcta ttgtgctatc gcttgtcaat ttggccttgg
     6721 caaccctgat ttaccttcca tttgttaaga tggctgataa tgagcttgaa aaggcaggtt
     6781 agtcactttg tgagaggata tatcggtttc atctggtata tcttctttta agcgctgaat
     6841 tgaaagcgtt tttataacaa ggtcgttagc ctgaccagca ctggattagg ctaaatgggc
     6901 ctttgaaaag ctattgtgtt taaaaatgat gtatatataa gtgaggaaat aaacatgtta
     6961 tttaatccta tcggaaaaga gcaaattaga aaatatgcca tcaaaaagct tagtgtcggt
     7021 gttgcttcag tgtgtgtggg tattggtctt gctgctggtc tgccagtggc tgtttatgct
     7081 gatgacgttt cagaggtaag cctgcagcag cctacgaaag cagcagtaac agagataagc
     7141 catgagcagg agcctcaagc tacagataca gatagcgagg ccttagtagt ctcagaggag
     7201 acgacagtag atgaggcagt agtagctaat gctgtgacca gcaatgctgc tgatcagaca
     7261 gcagacgaag agaagtctaa cgctccgatt gagctcaata aggtggctaa tggtggtttt
     7321 gacaatgatt atgtgtccaa taagaatcag tggcaatata gagagggagg tcattcagtc
     7381 ctcacaacag agaatggtaa tagctatgct gaggtaacaa gcggcacttt agatgagcat
     7441 atccttcaaa aggtgtctac aacggttggg aaaacctata cgctagaggc tgatgtgaag
     7501 gttgaagctg acacacctca taatggctta taccttaccg ctaaagagtc caatcacaat
     7561 cttcagggcc ctgttatcaa agaggtcagc ctcacagata cagacggtac ttggtcacat
     7621 atcaagctct cctttacagc aacgacttca gaaacctttg ttggcttagt caaatggttg
     7681 gaagcctctt ctccggaagc cttggctgcc tctgctagta ttgataacgt gagtgtcgta
     7741 gaggaaaatg attatgaatt gatttggcag gatgagtttt caggagatcg gttaaaccaa
     7801 gagaactggg gatatgaatt gggaagtatt cgcgggaatg agcagcagca ctacacagac
     7861 agcacagaga atgtctatct tgataatggc aatcttgttt taaacgtcac agagcgttat
     7921 ggggaggacc gttatgccaa tcctagagga ggaacaagcg cacgtcaggt catttatgat
     7981 tcaggaagcg tacgaacggt tggcaagcaa gaatttttat atggtcgtat cgaagctagg
     8041 gccaagcttc ccaagggtaa gggagccttt ccagcctttt ggacattggg ggctgatttt
     8101 accttagatg gtgatattgc gtcaactcaa ggctatggct ggccaagcac aggtgagctt
     8161 gacattatgg agctaatcgg tgctcctaac ggagagcatg agggtgagct tgccgaaggt
     8221 gatcaaagca acaaaacagt ttacgggacc cctcattttt actatatcaa gggtgatgca
     8281 gacaaagatg gaagctatag cccaacagca ttgggtggca atctgacatt aagtgatgac
     8341 ttttatgatg actaccatat ctttggtatt aattggtatc cggataagat tgaatggtat
     8401 gttgatggga ttgtttataa taccatgtat ttaaccggtg atgatcgctt agaggctgcc
     8461 gcagctgcct ttaataagcc tcaatacctt cagtttaacc ttgctactgg aggcaattgg
     8521 agtaaaaatg caggctacta tctagcttca gatgagacgg cctttgtgat tgattatgtg
     8581 cgttattacc aagatgctga gcaaaaagca gcctcagaag cttattatgc ctcacagcca
     8641 gttctcaagg gggtcaagga tttgaccatg ctagagggaa ccagtcctga tttagctcaa
     8701 gctgtaacca ctgatcagga aggctatgtg gttgattttt cagttgaaaa tgaatacttg
     8761 tttactaaca agggtggaaa taccaatgct gctttacagg ctgctggtcg agatgatttg
     8821 tcagccttgt ctgagctagc tcctggtatt tataacattt actatagtgc tgttccttac
     8881 aatgctgatt taggctcaac agtaacacca actgctaaga ttgcaagaga agtagctatt
     8941 ttaactgtat tacctaaaga aggtctgatt ggtaagaagg gagaaccctt atctacagta
     9001 gccctgccag ccaattggca atgggttacg ccagaggaga tcttgggaag tgcagagcat
     9061 tatcagatca aatacaccac agaaggcgga cgagctgttt atacaagcat agaagcaagc
     9121 tatatctcag atcagccaat ctcagatcaa gcatccattt tagttgattt aggcaatgct
     9181 attttggacg caacagcaga aaaagcagcc gtaacagatg acgaggctct tggtaagcta
     9241 gacgatgtga tgaacctaac ccaaggaact gtaacaatca gataccgtct agatactgct
     9301 gatacaacag tgagaagctc atcgcccttg gccttgttat cgatctcaaa tcaagcatca
     9361 gctaatgaat acgcctcttt ctttatcgag cctaaaaaca ataaaatagg tcttgaattt
     9421 aaaggagctg aggttccgat tgtaaaagtt ggctcaggct ttaatttatt aacgaactcg
     9481 gactggcaga cgatcagcta tgtctttaca gggtctaggc taaagattta cttgaatggt
     9541 gacttatatg gggaagctga ctttgctggg tttatgaagc aattaccttg gaaggcttct
     9601 gctgatacgc taacaattgg aggcttgaaa cgcacctatg atggtgagtc ggtccttcac
     9661 tgggggttaa agggactggt tgatcaggtg ctgattgata cagatgtgta tgatctgaca
     9721 gatattgcca aggctcatca gccaaccctt cgaccagtta ctggtgaaaa gacgaatgtt
     9781 tgggacaaat atgatgaagg ggtctttgaa tatcggattc cctctgttgt caaaacgcca
     9841 tcaggaacct tgatagccgc agcagatgca agaaagaagc actacaatga ctggggagat
     9901 gttgcaactg ttgtcaggat aagccatgat gatggcaaaa cctggagtaa taacattacg
     9961 gtcttagata tgccaactca gccttatttt acaacacaat atagcttggc tgattggaat
    10021 accaacatga ctcaatctgc tttttcaata gactccacct tgctaacaga cgcttctggc
    10081 aagctttatt tgctggtaga tgtctttcct gagtcacagg gtgctgttgc ttctaaagca
    10141 ggctcaggat atgaattgat taacggtcag tattatttaa atctttatga ttttgacaat
    10201 aataaataca ctgtgcgtga aggtggtatc gtctatgacc agagtggcca tcagacagat
    10261 atgtatgttg atgagggcaa ttttgagaca gcctttagca cacgcggcaa cctctatcaa
    10321 acagaggcag gagaggatat tctactaggg aatatttatc tgagaagtgg tcgcactaag
    10381 caaggcatca ctagagaagg ctcacaaaca gctcctctat ttacttacat gaccagcttt
    10441 ttatggctgc taaccagtga agacgaaggg caaacctggt ccacacctct tgatattacc
    10501 ccacaaataa aagaagactg gatgggattt ttaggtacgg gtgccgcagc tggcattgaa
    10561 atagacgcag tcaatgcaga gggtgagcag gtgaaacggt tagttttccc gatttactat
    10621 accaatcaac aaaatgcgac atcagctagt ctaggtcgtc aaagcagtgc taatattttt
    10681 agtgatgatg gcggtcaaac atggcaacga ggtgaatcac caaatgatgg cagaatttat
    10741 ggtcataacc aacaaacaac ctctaaggat tttgatacat cagtcacaga attgacagaa
    10801 aatcaaatca ttcagctaaa caatggtcac ttattacagt ttatgcgcaa taccggaaag
    10861 acaatcgtta ttgccagaag cacagactat ggtatgactt gggacgataa tcctacaatc
    10921 acagacctcc cagagcctta tgtcaatttg tcagctattc atatgatggt tgatggcaaa
    10981 gaatatgttg ttttatccaa tcctttagga gagccctcag gtgagcaact gacgattaga
    11041 aatcagcgca tgaaagggat tctgcgtgtc ggtgaggtct tagaggacga tagcattcat
    11101 tgggtcgctt caaccatttt tgagccaaag cgttttgctt actctagctt ggttcaacta
    11161 gacgacgaga gggttggttt gttatacgaa tatagtggtc agatcaccta ttcaaccttt
    11221 aatatcaagc agatgatctc agaccagttt cgtgaggata aggctgaaat tgaagaagta
    11281 acaataacgt cagcagctcc aaagcaaaat ggcaaagtaa gcataaccat tcagatgacc
    11341 tttaatcaac cgatgtttat tcttggtgat cgtcagttag cagttactgt aaatggcgta
    11401 gataagcttg ccagctatgt ttcaggagat ggcacagaca cagcgatatt tgaattgtct
    11461 ctggagagta tgcctgaagg accgataact gttttaccgc agtttgacca tactattgtt
    11521 gaaaccaaat atgggattag attgacagat gacaaggcat acactgtctc ttatcctgct
    11581 gctgtgacag catagcatga ggagtcagac tgtagatagt gtttacaatt gttaccataa
    11641 gataagttag cctgtctgct gaatggcctg ttcgctgttg ctagaatggg ccattccaag
    11701 ccgctcagca atgaggccta gtaggctaat agcaataata agtgaggaat taagcttgga
    11761 acgttttcag atttcagatc agttttattt agatggtaga tcgctgcaaa tcctgtcagg
    11821 ggctatccat tattttagaa ttcacccaga tgattggtat cattcgcttt ataatttaaa
    11881 ggcactggga tttaatacgg ttgagaccta tgtcccttgg aatttacatg aggctaggga
    11941 ggaaagctat gatttctctg gccaattaga tgtggaagcc tttttgacgc tggcgcagca
    12001 attggggctc tatgctattg tcagacctag tccttatatt tgtgcagaat gggaatttgg
    12061 tggcctacct gcttggctgc tgacaaagaa ttgtcatatc aggtcgtctg atcctgtcta
    12121 tttagcctat gtgaggcgct attatgagga gctgctgccg agactagcaa ggcatgaatg
    12181 gcagcagggc ggcaatattt tgatgtttca gcttgaaaat gaatatggct cctatggaga
    12241 ggataaggcc tatttaacag ctgttaaggg ctttatggag gagcacctca gtgcgccctt
    12301 gtttacagca gatggtcctt ggcgagccac tcttagagct ggtagtctga ttgaagatga
    12361 tgtctttgtg actggcaact ttggctcaag ggcacaggag aattttgctg acatgcaggc
    12421 cttcttttct gagcatggca agcattggcc tttaatgtgt atggaatttt gggacggctg
    12481 gttcaatcgt tggcatgagc ccatcatcaa acgcgaccct gaagagcgag ctgacgcagt
    12541 gatggaggtt ttggcgcagg gcagtattaa cctgtatatg tttcatgggg gaacaaactt
    12601 tgggtttatg aatggctgct ctgccagaaa gcaattggac cttccgcagg tgacctccta
    12661 tgattatgac gctatcctag atgaggctgg caatccgaca gctaagtttt acgcgattca
    12721 aaagcgtctg accgcggagc tttcagagat agaggttact cctcccttga ttaagccctt
    12781 gatgtcactg cctctgattg gtctgaagga caaggttagt ctgtttagca cgctggagca
    12841 catcagcagc tgtcagactg cttgctatcc tagtaacata gaggctttag ggcaatcaac
    12901 gggctatatc ctgtatcgga cacatctttt gaaggataag cgtgaggacg agcgtttacg
    12961 cttgattgat agtagagata gagcacaggt ctttttagat ggtcaaaagg ttgcaacaca
    13021 gtatcaggag acgattggtg atgatatcat cattaaccag cagcatgcct tgagtcaggt
    13081 cgatgtttta attgaaaata tgggccgggt caattatggg cacaagctga cagcacctag
    13141 tcaaagtaag ggtctaggac gtggtatgat ggctgacttg cactttgtga ccaattggga
    13201 gatgtattgt ctgccgcttg atgatttgtc tcagctttgt tttgatggcg atttttacga
    13261 ggggcagccc ggcttttatc attatcaatt tgaatgtcat gagcctgagg caagctatat
    13321 tgatatgact ggctttggga agggttgtgt ctttatcaac aatcacccta ttggtcgttt
    13381 ttgggaagtg ggtcccttat taacccttta tattccaaag ggctatttca acaagggatt
    13441 aaatgacatt gttatttttg aaacagaagg tgtttaccag gatagtatcc gtcttgttga
    13501 taggccaatt agtatagatt atccgcaagc tgatgacagg actgatcaga cctagcattg
    13561 tcagttgagg cttgcagcat tgcttggttt tctatttaca gacactaaag gccacaacgt
    13621 gcccttgggc tggcaaacaa taggctagct caggggcttt gtctttgctt gctggattgg
    13681 cgggcgagat gtgcttttct gatgctatag cggcagtgac tgcaaaggct gttcgtgaga
    13741 gttgctttct ttatggatta tgcgtaaaat aagaatgata acagttctta tcaaaggata
    13801 gtcctttgtg ctcaagctta ttgaggtttt gggtggggct ttctaatagt agcttataga
    13861 aaggaagcgt gtttgtaaca ttgagactga gtaaagagtg ctaaaactgg ctggttctgc
    13921 tggttttggt tatgtggttt ctttgttagc gcgtttggta tctttaatta tgcctgaact
    13981 ccctgaggtt gagacagtgc gacgcgggct tgagcgctta gtcgttggca agcagattgc
    14041 agcagtgacg gttagggtgc ccaagatggt caaaacagac cttgagcatt ttgtgatgac
    14101 gatccctggg cagcaggtgc aaggggtaga tcgtcgcggg aagtacctgc tctttgactt
    14161 tggccagctg gttatgatct cgcatttgcg tatggagggg aaatacctct tgtttcctga
    14221 tacggtacct gagcataagc attttcatgt ctttttgaca atgactgatg gctccacgct
    14281 ggtttaccaa gatgtgagaa agtttggaac ctttgatttg ctaccaaagg ctgagctggc
    14341 tgcttttttc cagaagcgtc agcttggtcc tgagccgacg aagcagacct ttcaattgaa
    14401 gacctttgag gctgctctgc tagcctctaa aaagaccatt aagcctcatc ttttggatca
    14461 gactttagtg gctggtcttg gaaatatcta tgtggacgag gtgctatggg cagctagagt
    14521 acaccctgag cgtcgatctg ctagcctgaa aaaggcagaa atcaaacgga ttcatgatga
    14581 aacgattcgt attttacaat taggtattga aaagggtggc tcgacggtta gaacctatca
    14641 gaatacctta ggaatgaatg gtagtatgca gcattatttg atggtctatg gccaaacagg
    14701 caagccctgt cagcgctgcg ggacctccat tgtaaagctc aaggttggag gaagagggac
    14761 acatgtctgt cctaggtgtc agaagcaatg acaaaggtaa ttggcattac aggaggtatt
    14821 gcctccggaa aatcaacggc tgtcgcactt atcagacaag caggctacca ggtgattgat
    14881 gcggatcagg tggtgcatga gctgcaaaaa aagggcggca agctttatca ggtcctacta
    14941 gagacctttg gacaggatat tttattgcca tcggggcaat tagacagacc taagctagcg
    15001 gagctgctgt ttgctcattc ggaaaatatg gcgaaatctt cccagcagca gaatgctatc
    15061 attagggaag ccttagccaa gcaaaaagag gagctatctc aaacagaggc tattttcttt
    15121 atggatttac cgcttttagt tgagctgggc tatcaggatt ggtttgacgc tatttggctg
    15181 ctctatgttg atgaggagac tcagctcaag cgcctgatga agcgtaatca attgacagag
    15241 ctagctgcta ggcagcggat tgctagccag ctgccgatgt ctcagaaaag agcttatgct
    15301 gatttagtga ttgataatac tggtgatttt caggctttag agacacagat tagtaaggct
    15361 ctgcatgatt tagaggcgta agccttgcca tgctgttgcc ctagtctagt ggttttggag
    15421 cttctatagc gtatgcaaaa agccttatcg tacccattcg tggtgcgata aggcttttgt
    15481 gctgcattag atggaccatg cacgcattat atactagtgc tgtcttgcat tagcttattc
    15541 agcttattgc tttcttttgc gttttgccag gaagcctagt ccaagaagag agagtaagcc
    15601 tgtaccaagt gcagtcatca agctgccagt gtcatttgtt tttggtagtg ctttgccact
    15661 agattggcta gtagcgtttg acggcttggt tggtttttga ggttttgtct ctggcttagg
    15721 ctctggttta ggcattggtt caggcttagg ctctggttta ggtgccggat caggcattgg
    15781 ttcaggctta ggttcaggtt taggctctgg ttcaggctta ggctctggtt taggcattgg
    15841 ttcaggatct ggcttaggct taggatctgg ttctggttca ggcttagggt caagtttagg
    15901 aattagagta gaaccaagca ggttttgata aggtttatgt taataatttt tttctgtagt
    15961 tatatatata tctaaatgat attctggttt ttcttgtttt tgagctgctt cctcaccgac
    16021 tttaatcagc tccataagag agttattttc ttgatcagtt aattcataat tttgtttaaa
    16081 ataatcttta ttataactat cactgaaata ccagatagct agttgagtta gtattcgact
    16141 tttagtgtca tctaatccgg ataaattttt attaggataa ccatttttca gtacagctat
    16201 tagcgcttta ccaatatctc cagatactct tggtttacta gcatttttag taaaggaatc
    16261 agttgtacct agtaatttat tatagatggg taatttataa gctgtttcag cattcactag
    16321 ttctaaggat cttccttctt cccaatttgc tggccattcc ttatctctgt tgaaacaata
    16381 gactattgta ccattttttc cggttttcct agtcgtttca tttgttggcg taacataaag
    16441 gaaaaaaggt gattttactc ttgttccatc attccaccca taatactgct cggctaggat
    16501 tctggctgat ccgccgataa agctacctga catgatgatg cagactgtcg aggctgccag
    16561 catcttcttc attgtttttc tcatgtttct ctcctttgag tttagaaata gtcattccta
    16621 aacctttctt cttcgtagaa tagctt
//
LOCUS       DARYMD010000043        15939 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.044, whole genome shotgun sequence.
ACCESSION   DARYMD010000043 DARYMD010000000
VERSION     DARYMD010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15939
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            1..183
                     /locus_tag="TU818_001459"
                     /pseudo
     CDS             1..183
                     /locus_tag="TU818_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(275..3910)
                     /gene="rpoC"
                     /locus_tag="TU818_001460"
     CDS             complement(275..3910)
                     /gene="rpoC"
                     /locus_tag="TU818_001460"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL0924262.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLVTEIAELKEELKTATGQKRIKAVRRLDVLDAFH
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVIREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKLWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLKPGQNIQEVIDSLPINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEEAEATE
                     EPAIIKE"
     gene            complement(4001..7567)
                     /gene="rpoB"
                     /locus_tag="TU818_001461"
     CDS             complement(4001..7567)
                     /gene="rpoB"
                     /locus_tag="TU818_001461"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL0924263.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            complement(7829..10129)
                     /locus_tag="TU818_001462"
     CDS             complement(7829..10129)
                     /locus_tag="TU818_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0924264.1"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VANDAISDNIKKAIVSTEDDNFQRHNGIVPKAIFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNLFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            10234..11490
                     /locus_tag="TU818_001463"
     CDS             10234..11490
                     /locus_tag="TU818_001463"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL0924265.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAREDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            complement(11525..12334)
                     /locus_tag="TU818_001464"
     CDS             complement(11525..12334)
                     /locus_tag="TU818_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL0924266.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(12327..13046)
                     /locus_tag="TU818_001465"
     CDS             complement(12327..13046)
                     /locus_tag="TU818_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL0924267.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKSRAGQVTIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            complement(13049..13492)
                     /locus_tag="TU818_001466"
     CDS             complement(13049..13492)
                     /locus_tag="TU818_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL0924268.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFAEELEG"
     gene            complement(13562..14413)
                     /locus_tag="TU818_001467"
     CDS             complement(13562..14413)
                     /locus_tag="TU818_001467"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL0924269.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            complement(14628..15152)
                     /locus_tag="TU818_001468"
     CDS             complement(14628..15152)
                     /locus_tag="TU818_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL0924270.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLTLDLAGVRPHFSI
                     TFDNGFDDTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            complement(15646..15747)
                     /locus_tag="TU818_001469"
                     /pseudo
     CDS             complement(15646..15747)
                     /locus_tag="TU818_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT         4634 a         3935 c         3091 g         4279 t
ORIGIN      
        1 atatcactaa tgccattgaa ctaccttatt ctaacgccaa gtttgaagcg actagcaaac
       61 tgatcaaaga catcaagcgc aatgcatttg gattcagaaa cgttgacaat ttcaagaaac
      121 ttatctatgc ttgctttgaa catgacaaaa gagaagacga ccttcgtctc ctctcgtgct
      181 tagttatcag tcacctacta tagttgacat ggagcccaat taatctaatg attttagcat
      241 gataaaagga gctaaggcta gctcctttta tttcttattc cttaataatt gctggctctt
      301 ctgtagcttc agcttcttcg ataacctcaa cctcattgat agcttgcggt tcaatgttac
      361 ggtaacgaac cataccagta cctgctggaa tgatcttacc aatgataaca ttttccttaa
      421 gccccaatag atggtctttt ttgcctcgga tagcagcgtc tgtcagcacg cgagtggttt
      481 cctggaagga agctgctgat aggaatgagt tagtctcaag tgaggctttt gtgattccca
      541 taagcactgg acgagaggtc gcaggaatac ctccagagat aacaatctcc ttattggcat
      601 ctgtaaagtc tgcaatatcc attaaggttc ctggcagaag atctgtatca cctggatcca
      661 tgacacgtac cttgcgaagc atttgacgaa ccataacctc aacgtgcttg tctccgattt
      721 ctaccccttg gctgcggtaa accttttgaa cctcagcaag caagtaggtc tcaactgaca
      781 aggtatcacg aacctcaagg aggtgcttag gctggattga cccttctgta agggcagctc
      841 cacgattgac ctcatcacca acctcaacct tcatacgcgc tgtaaatggc acaacatatt
      901 cacccatgcc tgttttacct tgaacgtaga ccttcttagt acgagttgat gcgtcctctt
      961 caatctcaat aacagtcccc ttaacctctg tgataactgc ttccccttta gggttgcgcg
     1021 cttcaaagat ttcttggata cgaggaagac cctgtgtgat atcggtatta gaggcaaccc
     1081 ctcctgtgtg gaaggtacgc atggtcagct gagtaccagg ctcaccaata gattgggcag
     1141 cgatagtacc aacagcctca ccaacctcaa ccgcatcacc tgtcgctagg ttgataccgt
     1201 aacagtgacg acacactcca tgacgagtag cacaggtaaa tactgagcga atggtaacct
     1261 cttcaacacc agcatcaaca atcttgcgag ccatgtcctc agtgattaat tggtcagcac
     1321 caatcaatac ctcaccagtt tcagggtgct tgactgattt acgagtgtat cgaccctgca
     1381 agcgctcctc aagtgtttca gtgacttcct tgccatctgt gatagctcga ataagaaggc
     1441 ctcggtctgt accacaatcg tcctcacgaa tgatgacatc ttgcgcaaca tcaactaaac
     1501 gacgtgtcag atagcctgag tcagctgtct taagagccgt atcagtcata cccttacgag
     1561 caccatgagt tgagaagaac atttccaaaa cagacaagcc ttcgcggaag ttagacagga
     1621 taggaagctc cataatacgg ccattaggag cagccatcaa gccacgcata ccggcaagct
     1681 gcgagaagtt agagatgtta ccacgcgctc ctgagtccat catcataacg attgggttct
     1741 taggatcctg tgtttcaatc agacgcttct caagggcttc ttttgcctcg cgccatgttg
     1801 ttgtgactgc aacatagcga tcatcatcag tcatcaagcc tcgacggaag gccttattaa
     1861 tttcctcaac acgatggtga gcagcctcga tgatctcagc cttgttgtca ataaccggaa
     1921 tatcagcgat cccaaccgtc aagcccgcaa gggttgaatg atagtagcca aggtccttca
     1981 agcggtcaag aaaggccgat gtttctgttg tacggaaacg cttgaaggtt tccgcaatga
     2041 tgttaccaag atttttcttc ttgaagggca cattgatcgg taagctatca ataacctcct
     2101 gaatattctg acctggcttc aagaaatatt tatctggagt gccctctgtc aagttagcat
     2161 tatttggctc ttggaggtaa ggaaggtcct ctggcatgat gtcattaaac aagatcttac
     2221 cgaccgttgt caccatgatt ttgtgtcttt gactatcctt ccaaagcttg cttggcatac
     2281 tgtcaacagc aataccaaca cgactatgaa ggtgaacata gccattacgg taagccatta
     2341 ccgcttcgtc cttgtcctta aagaccatac cttcgccttc acgaccagca tcttccattg
     2401 ttaggtagta gtttcctagc accatatcct gagaaggtgt tacaactggc ttaccgtcct
     2461 tagggttaag aatatgctca gcagcaagca tcaacaaacg agcctctgcc tgtgcttcct
     2521 ctgaaagcgg cacgtgaata gccatttggt ctccgtcaaa gtcggcattg taggcctcac
     2581 acacaagcgg gtgaagacga agagccttac catcaataag caccggctca aaggcctgaa
     2641 tccctaatct gtgaagggta ggtgcgcggt taagcaggac tggatgctcc ttgataacct
     2701 cttctagaat atcccagata cgctcatcgc cacgctcaac catacgctta gctgctttga
     2761 cgttgccggc aaattcgcgg gcaacaatct cacgtatcac aaatggcttg aaaagctcaa
     2821 tagccatctc acgtggtaca ccacattggt acatttttag cgttggaccc acagcaataa
     2881 ctgaacgacc tgagaagtca acacgcttcc caagcaggtt ttgacgaaaa cgcccttgtt
     2941 ttcctttaag catgtggctc aaggatttaa gcggacgact accaggtcct gtaataggac
     3001 gaccacgacg accattatca atcaaagcat caaccgcctc ttgcagcata cgcttttcat
     3061 tttgcacaat gataccaggc gcattaagct ccaacaaacg tgctaaacga ttattacggt
     3121 taatgacacg acggtaaagg tcattcaagt ctgaggctgc aaagcggcca ccgtccaatt
     3181 gcaccatagg acgaagatct ggtggaatga ccggcaagat gttcaggatc atccattctg
     3241 gcttattgcc tgatttatga aaggcatcaa gcacatctaa ccgacgaaca gccttgatac
     3301 gcttttggcc tgttgctgtt tttaattctt cctttagctc agcaatttct gtgaccaaat
     3361 caacacgctt taggaggtct tgaatagcct ctgcccccat tttagcaatg aatgagccat
     3421 gtccatattc ttggattttt tcacgatatt cacgctctgt caatagtgat tttggctcaa
     3481 gcggtgtgtc ctttggatca ataaccacat aagccgcaaa atagattacc tcctcaagag
     3541 cacgaggact catatcaaga gtcaagccca tacgagatgg gattccctta aaataccaga
     3601 tatgtgagac aggtgccttc agctcaatgt gtcccatgcg ttcacgacga acctttgcac
     3661 gcgttacctc gaccccacaa cggtcacaga caatgccctt atagcgaata cgtttatatt
     3721 tgccacacgc acactcccaa tccttggttg gtccaaaaat gacttcgtca aaaagaccct
     3781 cacgttctgg ttttaatgta cggtagttga ttgtttcagg ttttttaact tcaccatagg
     3841 accatgaacg gaccttactt ggtgaagcta atgtgatttg catactttta aaacgattta
     3901 cgtcaaccac tagttttacc tttctgcctt tgatgactta ctagcagcta gggcaaatag
     3961 ccctagtcta gtcattattt ctgttacaaa tgtttatgat ttagttgtct tcagttgatt
     4021 cagcaatatc ttgagtttcc tgagcctgct tttcacgcgc tttttcaaga tcgtcaacgt
     4081 gcatcacgtc atcgtcttcg ccttcatcaa gatcacgaag ctcaacttca ttatcgtctt
     4141 catcaaggac acgcatatca agaccaagtg attgcaattc tttcacaaga acgcggaaag
     4201 attctggtac accaggcttt ggaattggct tacctttggt aatcgcctca taagctttca
     4261 agcgaccatt cacatcgtct gacttatagg tcaagatttc ctgaagaacg tttgaagcac
     4321 cataagcctc aagagcccat acctccatct caccaaaacg ttggccacca aactgagctt
     4381 tacctccaag cggctgttgg gtaaccagtg agtatggtcc tacagaacgc gcgtgaagct
     4441 tatcatcaac catgtggtga agcttaatca tatacatgac accaactgac acacgattat
     4501 caaacggctc accagtacgg ccatcataaa gaacagtctt agcatcgcta tccatacctg
     4561 cttcacgaac agtttcccaa aggtcctcag acgtagctcc gtcaaagacc ggtgttgcga
     4621 tatggatacc caaattacga gcagccatac ctaggtgaag ctccataacc tgtccaatgt
     4681 tcatacgaga cggcactcca agagggttca gcatgatgtc aacaggggtt ccgtctggca
     4741 gatatggcat atcctcaacc ggtacaatac gtgagacgac acccttgtta ccatgacgcc
     4801 cggccatttt atctccgacc ttgattttac gcttttgagc aatgtaaaca cgcaccagca
     4861 tattaacacc tgattgaagc tcatcaccat ttgcgcgtgt aaagatcttc acatcacgta
     4921 caatcccgtc accaccatga ggaacacgta acgaggtatc acgaacctca cgtgatttat
     4981 caccaaagat agcatgcagg agacgttctt cagcagaaag gtctttttca cccttaggag
     5041 ttaccttacc aacaagaata tcgccttcct tgacctctgc accgatacgg ataataccca
     5101 tttcatcaag gtccttgagg gcttcttcac caacgtttgg cacttcacgt gtgatttcct
     5161 caggtccaag ctttgtgtcg cgtgtttctg attcaaactc ctccaagtga acagaggtat
     5221 aaacgtcctc cttcacaaga cgctcactca tgataaccgc gtcctcaaag ttgtaccctt
     5281 cccaggtcat gtaagcaacg attggatttt gaccaagagc catctcacct ttttccatag
     5341 aagggccatc agcgataaag tcaccctttt caacaatatc acctatttta acaagggttc
     5401 gttggttgta ggcagtacca gagtttgaac ggcggaattt tgtgatgtgg taaacatcaa
     5461 gtgaaccgtc ctcacgacgc acctctactc tttcagcatc tgaaaagaca accttaccat
     5521 tatgctgggc aattaccgca gcacctgaat catgagctgc ttgatattcc atacccgtac
     5581 caacataagg agcctttgga tcaatcaatg gcacagcctg acgctgcatg ttagctccca
     5641 ttagggcgcg gttggagtca tcgttttcaa ggaaaggaat acatgctgtc gcaacagcga
     5701 ctacctgctt aggagacacg tcaacaaagt caacctgact agcaggaaac tcttggttat
     5761 taccttggtg acgtcccatg acaatctctt cagcaaaggt accgtctgga ttgagcttag
     5821 aattagcctg agccactgta aactcatcct cttcatcagc agttagccaa acaatctcat
     5881 tagtcactcg gccaatcaca cgatcaacct tacggtaagg ggtttgaata aagccgtatt
     5941 tgttcagatg tccaaatgaa gacaggttat taatcaaacc gatatttggc ccttcaggtg
     6001 tttcaatcgg acacatacga ccatagtgag tgtagtgcac gtcacgcacc tcatagccag
     6061 cacgatcacg tgtcaaacca ccaggtccta aggcagacaa acgacgtttg tgcgacaact
     6121 cagacaatgg gttgtgctga tccatgaact gtgatagctg tgaagaacca aagaattctt
     6181 tgacagccgc cgttacagga cgaatgttaa taatctgttg tggagtcaac acatcgttat
     6241 cctgtacaga catacgctcg cggacattgc gctccatacg agcaagacca atacggaatt
     6301 ggttagcaag caattcacca actgcacgga tacgacgatt acctaagtgg tcaatgtcat
     6361 cgacctttcc aagaccttca gcaaggttaa ggaaataaga catctcagcc aaaatatcag
     6421 ccggagtaag ggcacgaacc ttatcatctg ggttagcatt accaacgatc gtcaccacac
     6481 gatcaggatc aactggtgaa accaccttga atttttgtag gatcacaggc tctgtcacca
     6541 ccgcataatc gtttggtgtg tagacaaact tgttcaaatc cccatcaagc tgctcttcga
     6601 ttgactcaat cacactacga gtcatctctg ttccagcctc aaccagaatc tctccagtct
     6661 cactatctat tagattttca gcaataattt gattcaaaag acgtgtcttg atgttcagct
     6721 ttttattaat cttataacgg ccaactgctg ccaagtcata acggcgagca tcaaagaaac
     6781 gagctgtcaa aaggctgcgt gagctatcag ctgtctttgg ctcacctggt cttaagcgtt
     6841 cataaatttc cttaagagcc tcatctgtac gtgaatcgct ttggttttta tgaatatcct
     6901 tttcaatggt attgcgaaca agctcactat caccaaaaat atcaataatt tcgtcatcac
     6961 cagaaaaacc aagtgcacgc actagcgttg taaatgggat tttacgcgta cggtcaatac
     7021 gagtataagc aatatccttt gagtcagttt ctagctctag ccaagcacca cgattaggga
     7081 taactgttga gccataacca accttaccat ttttatcaac cttgtcattg aaataaacac
     7141 caggagaccg aaccagctga gaaacaataa tacgctctcc accgttgatg ataaaggttc
     7201 ccatttcagt cataatcgga aaatcaccaa aaaagacctc ttgtgttttg atttcgccag
     7261 tttccttatt aatcaggcgg aaggtcacaa agattggtgc agaatagctt gcatcatgga
     7321 tacgagcctc ttcaagggta tatttaggct ccttaaattc gtaaccaaca aactcaagct
     7381 ccatcgtgtc tgtaaagttt gagattggaa gcacatcttc aaatacttcc ttcaagcctg
     7441 aatctaagaa atcttggaat gaatcagttt gaatttcaat caaatttggt aaatcaagaa
     7501 cctctttgat tcttgaaaaa ctacgacggg tacgatgttt cccgtattga acgtcatgtc
     7561 ctgccaagtt tttagctcct ttttcttttt aagctttgct atcaagcaaa caattgcaac
     7621 atcaatattt gtcttaagtg gtatttttag aatctttaaa tttttgttac aaaattgatt
     7681 tttatctaaa aataggcaca aaaagagcag ctaaatcgga ccttatcagt gtgatttaac
     7741 tgctgttctt tctagctgga caatatttca gctagattag acgacaaata gttatagata
     7801 ttatacacta tttgtctgga aaatacaact aatttcttct accactaaaa cctccccagg
     7861 ctttttgata gtctgcgtct gttccaccaa tggcaaacct ataggtagtt gctccgggtc
     7921 ccttttgagc ccaaaggctg gttgttagct ctccaccgat ggagatggtt tggccattga
     7981 tcgtcactgt acccggcttt agaccagtgg ccttcaagac agaagccttg ataacaccag
     8041 gatccagtga aaaccgctga ccaaggccaa aaagattggg atcagcctga ctgatggcat
     8101 taaccaaata agccatataa tttgaattat tattgtatcc cgtcagtggt gcaagcgagg
     8161 tattgtcatc atggcctgcc caaccaccca aagtaaccct tggagtagct aagaccagcc
     8221 agacatcggt ataattttcg gttgttcctg ttttacctat ccagtcagca cctgcaaggc
     8281 ttgggttgat ccctgctaat cggcttttaa aagtggttgt tgccccagat gaaatcggcc
     8341 ctctcaagag ctcctgtaaa atcgttgctg tcggagctga gaaaatacga accggcttgg
     8401 cctcatgctg ataaacaacg gatccatcac tagctgtgat actagccacc atatattgct
     8461 tttgataaag accattatta gcaatcatct gataagcatt ggtctgctgg gctaccgagg
     8521 tctcaatccc accaccaagt ggcagacttt caatggaata atcagcaatc cgatatccca
     8581 ttttactcat atagttttca acatcaacgc ccttatcacg cagcagcttt tgagtccaaa
     8641 aggctggaat attccatgag gtattaagcg cctcctgcag gggcatcatt gctgttcctt
     8701 cactatcgac gtgcatgatt ttttgaccgc tggaataggt cgtcggatag ttggatagga
     8761 cactagcact tcccattaat ccctgatcaa tggcaggtcc ataagcaata atcggcttaa
     8821 tgctagagcc tggagagcga acagtattaa aggcatgatt gttttgattt tgagcatagt
     8881 ctctcccacc aataaagccc aaaacagcac ctgtagcatt gtccgttagg acattgccca
     8941 tctgcactgt cccagtgcca tcatctaaca agccaccaaa ctgagctgcc gctttttgca
     9001 tcacctgatg gattggctta ttgattgttg ttttgacagt gtagccgcca tgctgcagct
     9061 cagttaaggc tcgctcctca taggcagcct tagtctcatc attttttaaa tctttagcag
     9121 gcaccttatc tcgcttaatc agatagctat acatggcctt ttgtgcctct gccaagacag
     9181 aatagtagag gtaatcatga gtattggcag tgactgtttc aggtttgata aaatcattgc
     9241 taataggata tgccttataa tcacgatatt ctttttctgt cagcacacct gttcgataca
     9301 tattgtagag gacattttgc tggcgcttaa tcccataggc catatcatcg gctgatttta
     9361 actgccctgt cggcaaatac ggcgaataaa caatcgggct ttgcggaagc cctgccaaaa
     9421 aggccgcctg cggaaccgtc aaatccttgg cagagactcc aaaaatgcca cgcgcagcct
     9481 cctccacacc tgcaatgttt tgtcccttat tattacgacc aaaaggcgac acgtttaaat
     9541 aatgtgataa aatatcgtcc tttgacatgt aacgctctaa ggccagtgca tagataattt
     9601 cctttgattt tcgcctaaag gtcggatcat cgcccaagac ttgctgctta atcaactgct
     9661 gtgtcagcgt agagccacca cttgactccc caaagcccaa aacagaggcc agagtcgcac
     9721 gaaaaatcgc ctttggcaca atgccattat ggcgctgaaa gttgtcgtcc tcagttgaga
     9781 caatagcctt tttgatattg tctgaaatcg catcattagc aaccggtgtc ctaagcagat
     9841 ccgtatcaat gcctgaaatc aagctattat ctgaataggt aatctgtgac atcatggtca
     9901 atgattcaac ctgcttgaca agactttcct tacttggaat ttttaccgag tcaatttgac
     9961 tggctaaata gccaaaggcc ataccagcac ccagcatgcc aaataaaaag acagctacat
    10021 aaaaaaagct cgacatgaat tttaatgtgc gcaaaaagac cgttccaaaa tcaactaatt
    10081 ctaatcgctg atgatttttg cttgtttgat tctttttcca tttcaccata acgtacctca
    10141 atcttcatta taccaaactt tgattaagct tgcacagcca cagtcatttt tgatataatg
    10201 attcggaaat cataaagaaa atggagaaag cctatgaata tttttgaaga actcaaagct
    10261 cgtggcttgg tctttcagac gaccgatgaa gaagcccttg tcaaagcatt aacagaaggg
    10321 caagtatcct attacactgg ctatgatcca acagctgata gcctgcatct tggtcatctc
    10381 gttgccattt tgacatcacg tcgcttgcag ctagcaggac acaagcccta cgctcttgtc
    10441 ggtggggcaa ctgggctgat tggtgatccg tcctttaaag acgctgagcg tatcctacaa
    10501 accaaggaaa ccgttcttga ttggagccaa aagattaaag aacaactctc ttgctttctt
    10561 gactttgaca acggtgaaaa caaggctgag cttgtcaaca actatgactg gttctcacag
    10621 attagcttta ttgacttcct tcgtgatgtc ggcaagcact tcactatcaa ttacatgatg
    10681 agcaaggatt cagtgaaaaa acgtatcgaa accggaattt cctacaccga atttgcatat
    10741 caggtcatgc aaggctacga tttttacgag ctaaatgcta agcacaatgt gacactgcaa
    10801 atcggcggct ctgaccagtg gggtaatatg acagcaggta ccgaattgct ccgcaaaaaa
    10861 gctgacaaga ctggacatgt gatgacagtg ccattgatta cagatgcaac aggtaaaaaa
    10921 ttcggcaagt cagagggtaa tgcgatttgg cttgacgcta aaaaaacatc tccttacgag
    10981 atgtaccagt tctggttaaa tgttatggac gatgatgcgg tacgcttcct gaagatcttc
    11041 accttcttat cacttgatga gattgctgct attgaggagc agttcaacgc agcacgccat
    11101 gagcgccttg ctcaaaagac acttgcgcgt gaggtggtga cactggttca tggagaggca
    11161 gcctaccagc aagccctcaa tattaccgaa cagctttttg caggagctat caaaaacctt
    11221 tcagcagctg agcttaagca aggcttaagc aatgtcccta actatcaggt tcaagcagaa
    11281 gacagcctaa atatcgtgga tatgttagtc acagcaggca tttcaccatc aaaacgtcag
    11341 gcgcgtgagg atttacaaaa tggcgcgatc tacctcaatg gagaacgact tcaggatctg
    11401 gattacagct tatctacagc agatcgcatt gacaatcagt tgaccgtcat tcgccgcggc
    11461 aagaaaaaat acgctgtact aacctactaa tcacagacag ctaggaaaat cttgctttgg
    11521 atgattattt ttgacgtata aaggacagca ggttaaccac aaggaagatc gcaataaaaa
    11581 tcatcgtaat ggtcgcactt gccggcgttt cccaaaaata ggacaagaaa ataccagaca
    11641 gcatgcctgt aaagccaatc ataatcccaa gaaaaataac tgatttaaag tttttcccaa
    11701 gccgcatagc aatacttgct ggcaaaacca taatcgttga taccaaaagg gcccctgccg
    11761 ctgggatcgt tagagcaata gcaacacctg tcacaatatt aaacaagaca gacatgacac
    11821 gcaccggcaa gccatcgacg taggctgtgt cctcatcgaa ggtcaagata tacattggac
    11881 gaataaataa tatcgtcaag gctaaaataa tcaaagcaat gacaaataag gcagcaacct
    11941 gctccgtact aatagtaatg atagagccaa aaaggtattg ctccaagctc atactagaag
    12001 agctagttga cttactcatg ataatcaagg aaatagccag ccccaaggac attaggatag
    12061 ctgtcgaaat ctccatatag tgcttataaa ccaccctaag atattctagc aagatggcag
    12121 ctagcaccac cacaataatc gttgtgaagg ttggcgaaac accaagaaca acaccaaagg
    12181 ccacaccagc cagagaaacg tggctaagcg tatcactcaa caagctttga cgacgcaaaa
    12241 tcaaaaagat acccaaaatc ggagcaaaga tactgatcgc cacaacagcc ataacagcac
    12301 gctgcataaa atcataagat aaaatctcaa gcatggaatg accctccttt gctctcatca
    12361 gcctcagcat catgaatgtt gaagcaacgc caaggaagcc gttgatttct aatcaaatga
    12421 atattgcgat cagcataagc cttgacctcc tctgggtcat gtgtaatcat caaaacagcc
    12481 ttaccatgtc tatgagcgct gtggtgcatc aactcataaa aagtatctgt tgttccacta
    12541 tccattcctg tggtcggctc atcaagcaca aaaatatcgg ggtcagaagc aaacatacgc
    12601 gcaataacca cacgctgctt ttgaccacct gatagactcc ctattctctt atgccgacta
    12661 tcccacatgc caacagactc caagcttgtc cgaacatgct cctcatcgtg cttacttagt
    12721 ctggtaaacc aaccacttct aggatatctg cctgatttaa caaattcata aacagtcgac
    12781 ggaaagcctg cattaaagct ggcaacctgc tgtggcaagt aagcaattct cagctttttc
    12841 ccatgaatgt tctgtttagc tatagtcacc tgcccagccc ttgactttaa aatccccaag
    12901 gtcgccttga tcagggttga cttggcagca ccattttcac cagtcaatgt gacaaattct
    12961 ccactatcca aatgatagct gattccctct aaaacaggct cactgtcata ctggaacgag
    13021 agattttcca ccgatatgta tctcattatt acccttctaa ctcctccgca aaagcagtga
    13081 taaatttttc aacaatcacc tgctcctccg cagaaaaatg tgccaacaaa cgatgataaa
    13141 cagctagtgt tttatcgtga tgatgtgtat gctccttagc gattggcctt gctagatcag
    13201 tcagttcaaa ataggttact cgagcatcaa cggtatcctt tgttcctgct agcatttctt
    13261 gcttgatcaa gcctttaatc gctttagtta ctgctgcttg actgatattt agcctttttg
    13321 ccaaatctgt attggttagc ttttcctgtg acaaaagcat caaaatatgc tcctgagtat
    13381 ttgttaattt gacatcactc tgacaagccc caaagagcag ctcatgctga ttttcagcct
    13441 ttaacaaaat acgattaacc aaattatcaa gctttttttc taaaattgtc atgatttccc
    13501 tctcctcatt aaccagttaa ttataacatg acgccccaaa agacgcaact tcaaggctga
    13561 tctacagcgt tctaaccttg tagacttcct tacaaaagcc tttcaggcta ttcaccacac
    13621 gattggcctg cttttctgtt tgacataggg caaataccgt tggaccactt cctgtcatca
    13681 gggcaatgtc tgctcctgac tgcagcattt tatccttaac cttttgaata aacggccgtt
    13741 tagcaatgga aatatcctct aaggaatttc ccatcgttgc aagcaagcgc tgataatcac
    13801 ctgcctcaat ggctgaaacc agatcctcaa tcggcactcg agatatcgtc tcacaatcaa
    13861 tatcccaaaa aatcgttcta gtagaaatgc caaattctgg cttcactaga accacccaag
    13921 aggacaagcg gccattgatt ggcttaacca cctcgccttt gccagtcact tgggcgcagc
    13981 ctgcaaaaag acaataaggc acatcgctac caatctgcat gccaatgtca atcatctgac
    14041 ggggactaag ctttagctgc cacagctgat tcaatgctct gattgctgca gccgcatcac
    14101 ttgagccacc tcccatacca gcacaaacag gtaccctctt atccaagaaa atagagacac
    14161 ctgttgagat ttgaaatcgc tctttcagca aataagccgc cttgtaaacg tcattgtgct
    14221 cattaatagg caatctaggg caattagagg tcaataaaat cctatcctcc tctaaatgat
    14281 ccactgtaat ataatcacaa agatctacac taactagaac catagatagg tcatgatagc
    14341 catctggtcg cttgccttga atatctaagc ctagatttat ttttgcagga gctctctcaa
    14401 tgattgcagt cataatactc ctttatttga tgtcattata gtatcaaata tacacaatct
    14461 tcatgaaaaa ttcaaataaa tacagttagt atctaatgat gcatagacag cgtgtttgta
    14521 tcaaaacagc caaccatttg tccctactag cgtgaggctt caccagatca gcagccaaaa
    14581 aacgacaact actagcatag caagcaaagc taagacagca gcagtctcta tgaccacttg
    14641 atcgctccat attgccccac taactcaaag cacatatcaa tcttgctctt aaagtaggga
    14701 ataaaaatac cagcatcaat catggctaaa atctcatcac gactagccca tcgaacagcc
    14761 tgtacctcct ctgtctgaag aactagcttc cttacatcaa cagcctgcaa aatcaaaaaa
    14821 gtatcgtcaa agccattatc aaaggtaatt gaaaaatgag gccttacacc agctaaatca
    14881 agagtaagtc ctagctcctc cttcagttct ctcatcactg cctcttgtga cgtctcacct
    14941 gcaagagcgc tgccgcctac cgttatatcc caatagctgg gccaaccctc tttatccttt
    15001 tgccgctgct gaatcagcat ttctcccttg tcattaaaga cacaggcgtg aaccactaaa
    15061 tgataagcac cctctacaaa agcagctcca cgctccatga gtctaccagt cttaagacga
    15121 ttcatcgtat aaatgtccca atactcaacc atacaaacac acctcctgat acagctatta
    15181 ccagatccag tatattaatc atatcacaat aagcatatcc aaaacaacca ggtccagaca
    15241 aaacaacaat taccaaccta gcttaattct tttttctaca attccctacc ttaaaatgcc
    15301 tcgcatagaa aatggacaaa aagatctgtt ttcccgagac gtatcaaaaa gctcaccacg
    15361 ctaacaaact ggtagttaag atccccaagc gtcttactca gttaacgata tggtgataca
    15421 cacagctgac ttgcctcatc atattagtta caaaaaacct taaaggctca acccaaaagc
    15481 acaccaacta catcacccca tgaaagagga agacaaaaca tctactgctg caagcaaaaa
    15541 gagaccccat tagggcctct ctagtgctca tatcagcttt taaactaatc aatcgccttc
    15601 aagctaaagg ctatcattta gtaggagaaa gttgcaaaag ctaatttagt tgttttttct
    15661 ttttagagtt agcaggcctg cgctggcaat gacgccgaga gctgcaaggg tgaagaatgg
    15721 gtgatttgtc tctcctgtag ctggtaatat acccttttga gctgctggag ccgctgattt
    15781 gcttggtgct gacttaggcg ctggtacctt aggactagct gactgctgct ctgaagtctt
    15841 tggtacctgt ggagcaggag attgctccgg ggcctttgga gctgatggtt tggtatcctt
    15901 tccttgctcg cccttttcac cgcgttggct ttgttcacc
//
LOCUS       DARYMD010000044        15902 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYMD010000044 DARYMD010000000
VERSION     DARYMD010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15902
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(93..563)
                     /locus_tag="TU818_001470"
     CDS             complement(93..563)
                     /locus_tag="TU818_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL0924271.1"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEDFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
     gene            784..1634
                     /locus_tag="TU818_001471"
                     /pseudo
     CDS             784..1634
                     /locus_tag="TU818_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            1970..2260
                     /locus_tag="TU818_001472"
     CDS             1970..2260
                     /locus_tag="TU818_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEL0924272.1"
                     /translation="MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTANA
                     NTTVNLLSAYSTVSSVVAIVGAVTGVGSIGAGIAATVLYLIKQKGKAAAALW"
     gene            2274..3413
                     /locus_tag="TU818_001473"
     CDS             2274..3413
                     /locus_tag="TU818_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924273.1"
                     /translation="MKHVFKYHKGDILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVT
                     IGIICLAIAFPEQLVWIALSVLAVFIYWLSLPLVAIFRVAGRLLNLLMIYGMYLNQEL
                     LVIACLCLNVVILVLSVTINVHYPYQWLAVRARKEEKTITLLKLVINTITDHLALMVL
                     FSIFCIAVTYFTQRLLLSFDYSSFSIPVFFLSASTYIALLEVMVGKNIKELELDRGLA
                     VLQFLNRDISVYKAYRNSQFLLSAHILAVIHTGCAIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSLKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            3410..3892
                     /locus_tag="TU818_001474"
     CDS             3410..3892
                     /locus_tag="TU818_001474"
                     /inference="COORDINATES: protein motif:HMM:NF014052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEL0924274.1"
                     /translation="MIMRKFLRYYISFIIFSIAIGILIGLLITSDTVILSKPERGWDF
                     TLEVLKNNSNNFLSYIFLFFLSPALQLIDLVSVVIQITLGMRKSGFLITALGLFPHGL
                     LEIPNFLFYQGLSQYMLWTVLTEKSMTSFLERERRYVRYYLISYYVLLIAGIMEGLLG
                     "
     gene            3889..4476
                     /locus_tag="TU818_001475"
     CDS             3889..4476
                     /locus_tag="TU818_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0924275.1"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVIN
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALSTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHQQLLSESQVIYLNGKGEIY"
     gene            4473..4955
                     /locus_tag="TU818_001476"
     CDS             4473..4955
                     /locus_tag="TU818_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924276.1"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEVLL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLSALLLKLSPSPLFQFVVNALGIVIMYGLSIKRQGNRTTALLFCLPFTLDILATLLL
                     "
     gene            4980..5495
                     /locus_tag="TU818_001477"
     CDS             4980..5495
                     /locus_tag="TU818_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924277.1"
                     /translation="MKKILYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLAKLYSDDMLGATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSS
                     VEPASSIGIDV"
     gene            6129..7763
                     /locus_tag="TU818_001478"
     CDS             6129..7763
                     /locus_tag="TU818_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924278.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKAYDGKNHTLDLRVTFKTFTVTSNVRDGELYIDGERV
                     ETLKAGQLQLEEYPVTEIAKAYIKKTFPDGELTSSKHSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(7904..8797)
                     /locus_tag="TU818_001479"
     CDS             complement(7904..8797)
                     /locus_tag="TU818_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL0924279.1"
                     /translation="MTTANKPEMGFQISFINPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPGLVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLA
                     QEMIRVTAPSKSFKEGLQQLN"
     gene            complement(8781..8972)
                     /locus_tag="TU818_001480"
     CDS             complement(8781..8972)
                     /locus_tag="TU818_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924280.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVTLAT
                     QMAINLIEKYHDWLNDNSK"
     gene            9207..10961
                     /locus_tag="TU818_001481"
     CDS             9207..10961
                     /locus_tag="TU818_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL0924281.1"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQGRTYNDTPYYS
                     AYHHYYDHTRDTADNGIDNWGRLTRYHYYRETYYQLEAERQQLVRTYLELKASYDDQV
                     ALSSQRLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNFQSYQTLLQQLSMAD
                     FVSQYKDRLDTLTRLDTERARLIDTWWESDSNYSDLNTNLTLVNGYIKELNQALQELL
                     KDHQGKMTSDLQTLGDRQAELARRLTDIESRPKRQATSQPRGSQTHWRSAPRADVALW
                     NELRNEGDYASATTDNALPLQPYRADLTAVHDLEALQAQSDRAHRLRAKEIVFTLQRS
                     NISRQGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMT
                     DDQYKEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQ
                     TPYAFIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQ
                     YYHIDLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRSFLRYG
                     TYATNYSRNTFYPGYSYA"
     gene            11102..11482
                     /locus_tag="TU818_001482"
     CDS             11102..11482
                     /locus_tag="TU818_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL0924282.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEVVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKFLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            11520..13853
                     /locus_tag="TU818_001483"
     CDS             11520..13853
                     /locus_tag="TU818_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0924283.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTERQSVLQRSKSYGVKRKNRPIWLQRLEAILPSQQGPIRRFLRRYHVGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIEKATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETIPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSETKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKVDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            13902..14054
                     /gene="rpmG"
                     /locus_tag="TU818_001484"
     CDS             13902..14054
                     /gene="rpmG"
                     /locus_tag="TU818_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL0924284.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            14066..14242
                     /gene="secE"
                     /locus_tag="TU818_001485"
     CDS             14066..14242
                     /gene="secE"
                     /locus_tag="TU818_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL0924285.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            14633..15178
                     /gene="nusG"
                     /locus_tag="TU818_001486"
     CDS             14633..15178
                     /gene="nusG"
                     /locus_tag="TU818_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL0924286.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
BASE COUNT         4571 a         2904 c         3515 g         4912 t
ORIGIN      
        1 atcaaggctt ttgcaggaga tttatgaaaa agaaaaattt aggatagtgt aagtataagc
       61 tagtttcctt aagaaaagct taactgaagc aattaatcgt agagatgggt gattgttttg
      121 acgacttttt tctccttgtc agaccaataa tgaaggcgtt caaaagatcc ttgtcgccag
      181 tagagtggta gcctttgtcg aatatcctct tgcatgtcta gcttatctag atcagcaata
      241 gcatgccatt gtggtaggcc ctctcgtgat ttagttagca gcttgccttc aaaatcttcg
      301 caaagaaagt cataataaac atagcgctca ggcttatcag gattggtaaa gcctgagatt
      361 ccctttaatt gcagatttaa ggcggttaag ccggtctcct cctttagctc acgcactgcc
      421 gcttcaaaaa aggattctga ggtgttaacc ttgccacccg gttggatcca gccaggaaaa
      481 tcgtcatgct ggcggttgag aagtaggatc ttgtcgccct ccttgacaca gatattaacc
      541 caatttttga tgacttcaag cattagttac ctcgttttta gttttatttt atcaaaaaaa
      601 gatcagtatg aatagctgag agatttattg atatggtcat aatggcttca gatagtttta
      661 ctgctgcttt agccatctgc ataaataata taaaaatacc atttcacatc attatttaat
      721 agatttatta tcatattaat ggtataatta tgtgaaatta gaactatgtg tagagagagt
      781 ataatgaata gtacagattt gatgagactg ggagagcttt ataaggagct tcgtattgct
      841 cgtggactta ggctaaagga cgttgctaga gacaatttat cagtttcaca gctatctaag
      901 tttgaaaatg gccagagcat gctggcagct gacaaactac tattagctat ttcaggaatc
      961 catatgacat tcgctgaatt tggtcatgct gtaaatgggt ataaagtcag cgattttttt
     1021 cagttaggca ccaaggttgc cgagctacaa acagcatcag atatagatgg attgaaggag
     1081 cttctgagcc aatataaggg tgatgacatt ttttctgttt ataatagatt aaatgaatta
     1141 atcattaaaa gtgctatcta ctcacttgat ccaaatgtta aaattgaaga atcagacaag
     1201 caattgttga cagaatacct ttatagtatt gaagagtgga cggagtatga gctatacatt
     1261 tttggcggtt gtttggctat tttatctgat gaggatatga tttttttggg aaaagcattt
     1321 atcgaacgag ataagatttt cctttctctt ccacaacata gaaaggcagc tcacatcact
     1381 ctcttaaata ttatcatgac aaggcagctt tttatgttga tttttttatt aaaaagctgg
     1441 aggagttgat tatctatcaa gatatgttca ctatagtgag cttaaatttt tttaagaaaa
     1501 tatataccta cttaaatgaa gaaagtaagc ataagagcga cattgaagat tatattaatc
     1561 ttgttaaaca gcttggcaac cctcagtttg cccaaattct acatcggacg ctatcagtga
     1621 ttctagatag ttaatactaa aaaagtagcc caatcgtttg gtggctacag tggccaaggc
     1681 caccaaatag acaaaagggc taataagaaa ataaaagctt ttcgcataat atctcacctc
     1741 cttgataagg atattataca aaggggaagc ttcaatctca aacattcgca aatatgaaaa
     1801 tattaacaaa agcatcatca tatttgcgaa tatcgagaat atgataattg tcgtgatata
     1861 attactgtgt taatgattta gctaggcatt aataaatcta aatatagact acaggcaggt
     1921 cgctcgttat actagtttga gggccaatgg tctgggtagg aggaagcgta tggcgacatt
     1981 agagcgacat cataaaatgt tattattgtc aatggcatta ggggcagcga gctggttagc
     2041 actcggattg attagcttgc caaatcttgc aggtgcttta ggaataagta ctgctaatgc
     2101 caatactaca gttaatttgt tgagtgctta tagtacagtt tctagcgttg ttgcaatcgt
     2161 tggtgctgtt acgggtgtag ggtctattgg agctggaatt gcagctaccg ttttatacct
     2221 tatcaaacaa aaaggaaagg ctgctgctgc tctctggtag ttaattgtct gatatgaagc
     2281 atgttttcaa atatcataaa ggcgacattt tagggtatct caatattgtt gggtttaccc
     2341 ttttgtttta tggctcagtg ataggtatga taatgttcag ggattatttg acctatgatg
     2401 gagctggttc tctaatatcg acctttattc tggtatcagg aacctatcat tctgtgaaat
     2461 caacatttcc atatgaaggg aagcgtcatc caacttttat attaacaccc tattatctat
     2521 ttaagcatct attgctttca gttacaaagg tttatgcttt ccagatccga gtggttacta
     2581 taggaatcat ctgtttagca atagcctttc cggagcagct tgtttggata gccttgtctg
     2641 tgctagcagt atttatatat tggctatcgc ttccgctagt agccattttt cgagtagctg
     2701 gacgactcct gaatcttctc atgatttatg gtatgtatct taatcaggag ctgctggtca
     2761 ttgcttgtct ttgtttaaat gtggttattc ttgtgcttag tgttacgatt aatgtacatt
     2821 atccctacca atggctggcg gtgagagcta ggaaggaaga aaaaacaatt accttgttaa
     2881 agcttgttat caatacgata acagatcatt tagctttaat ggttctgttt agtattttct
     2941 gtatagctgt gacctatttc acgcaaaggc tgctgctaag ttttgattat tctagcttta
     3001 gcataccagt ttttttctta tctgcttcta cctatatcgc gttactagag gttatggtcg
     3061 gtaaaaatat taaggagctt gagttagacc ggggcttggc tgttttacag tttctgaata
     3121 gggatatcag tgtttacaaa gcttatcgca acagccaatt cttgctttct gctcacatct
     3181 tagctgttat tcatacagga tgtgccatag gcttactacc atttttacta aatggtcaag
     3241 ctgctctttt tctgtctaac ctagtgatga tccccttcat ctactttata tcattttgct
     3301 atttcgtgaa atcactaaaa atagttgctg gtgatttgtc agtgtttagg tgggttattc
     3361 tggttttgta ttttatacta gtggtcattg caatggtagg tagtcgttta tgataatgag
     3421 gaaattttta agatattata tcagttttat tattttctca atagcaattg ggattttaat
     3481 cggtttgctg atcaccagtg atactgtcat attatctaag ccagagcggg gctgggattt
     3541 tactctggag gttttgaaga ataatagcaa taattttttg tcctatattt tcctcttctt
     3601 tttgtcccca gccttgcaat tgattgattt ggtatcagtt gttatacaaa ttactctagg
     3661 aatgaggaag tctggatttc taataactgc cttgggtttg tttccgcatg gtttgctgga
     3721 gatccctaat tttctctttt atcaaggctt gagtcaatat atgctatgga ctgttttgac
     3781 tgaaaaaagc atgacgtcct tcttagaaag agaaagaaga tatgtaaggt actatcttat
     3841 atcgtattat gttttgttaa ttgctggtat tatggaaggg ttactcggat gaaaatagta
     3901 aatgaaagca agtcattttc aaacagaaaa atcttaaatc acatatcctt tgactttagt
     3961 aaagggctgt ataaggttga agggaataat ggtagtggta aaaccacttt tttgcgcttg
     4021 ttagcaggct tagaacggtt tgatagcggc catcgcttac agcataaggg agatattcta
     4081 tatcttgata ctaatgctat cggtgtagtt cccttaacta ttgaagacaa tctgacatta
     4141 ttatggaaaa cctttaatgc ctctcctgat gaggagacct tgtctgtgat taatcagttc
     4201 tttggagaac ggttactaga tcattatctg acggcttctg taggaacaaa ggctaaggtg
     4261 ggcttatcct tgctttttgt aaaggattgg gattatattt tcatagacga agccctatca
     4321 acgcttgatg ggtttagtct tgatatggtt gcaggaagat tattagcatt aaaagaaaag
     4381 gctactgttt tttacgtttc tcataatcta tcacaccagc agctattgtc agaatcacag
     4441 gtgatttatc ttaatggaaa aggagaaatc tattgaaagg taatcctttt aatcgtaatc
     4501 tttcttggtt aatagcctat gtgctattac tttcttgtta tgtattcata ttagtagatg
     4561 gtggtttttt aaaaaacagc gttcaagaat tggaagtcct gctcggccaa acatcactag
     4621 ctataaagct gtttttgatg gtgatatcaa tagcttttag catcatatct ttactggttg
     4681 agtatttttt aagcaaattt ttagtgctgc tttttattga agctggcatc gtttctttaa
     4741 atgatgttct tactgctaaa tcagtgactt tagtgatcca tttatctgct ttgctattga
     4801 agctatctcc ctctccactt tttcagtttg tagtgaatgc tttagggatt gtgatcatgt
     4861 atggattgag tatcaagaga caaggaaata ggacaactgc tcttttgttt tgtttaccct
     4921 ttacactgga tattctagca acattgttgc tttagtgatt ttgagttgga ggaaaagtaa
     4981 tgaaaaaaat cttatattta tcagtacttt taggaacgtc aattctagca acattgatta
     5041 aaatttataa cacttttttt gcaaagctaa aggcttcatc aggtcattca actgggaata
     5101 tagagattga tgccctttta tctgagtcta gactagtgtt ggaaaggcag catgccttca
     5161 caacaaatgg aatcaacaag ctattcgtta tgatgatgag tctaatgctg ttattagcct
     5221 tatactatct gataaaaaag gatttgaagg ccgtctatag ttatttgctt tacctggtgt
     5281 taaccttggt tcatgcaatt tatagcttct tttcgttaag tcccttggca aagctttatt
     5341 ctgatgatat gctgggggct acaatccaga cgggagagaa agctaaattg attttttcag
     5401 tggttctttt tcttctttat ctgcttattg ttgtggccaa taatagagta aaatctagtg
     5461 tagaacccgc ttcatctatt gggatagatg tgtaatacct ttcatattat gacctttaaa
     5521 gccttttagc ttctctaatt ttcagagtaa ctaggaggct gtttgtgacg ctctgagcgt
     5581 tttttcgttt ctatcaaagt ttagctgcgt taatgctatc tatttccgta gctgagatac
     5641 aagatattat aatatgtgtt gtcataccat aaaaacacct tacaggatat tttatgatca
     5701 atcctccttg aattaagctt tctttaagca agggtgtgta tactagccgt aatcctaaat
     5761 aattggttac ctaatgataa ctaatttttt cataacctcc ttcctaaaaa cgatgtcagg
     5821 gcagtcagga ttgattgctg ttatggcatc gtttttgttg tactttgata ggggatctag
     5881 ctgtatgtta aatagcctat caggattgag tggcgaagat gatcaggagt ctcttggctc
     5941 taggttatgc tgctgtttca tgagaaacag ctcttgatga tcaatttagg tagtattagt
     6001 ggtggtcatc ttagcctttt aggctttgag ctgctttatg tttgctcatt tttaatatgt
     6061 tagtgtttac acaaataatt ctcatttttt gatataatag aaaaggtaag gaagggtagg
     6121 agataaggat gacaagattt tttcaaaaaa aacaggccaa aagcttagcc attggttttg
     6181 tgagcttgtt tgctgtgctc attgggtatg gagcttttca ctattctaag gccagtcgta
     6241 tcaatgccta tctacaagca aggtcatcag gctctgggca ggtgcttgaa aatatcaagg
     6301 aatacctcgt gtgggcagat accaatgagc agctgaccaa tgatcaagca agatacacca
     6361 gctttaagag atacagtaag gcagagctag taagcaagcg tcagcagctg caaacagcaa
     6421 ctgcagctga tgatatgtat gtcaaatcgg ttggtcgcaa atttttgatt ttccctgatt
     6481 atcgcatagc agtgaagcct gtagccttga caatcaagac caatgtgcca aatgttgata
     6541 tcttgttgaa ccataaaaag attgctgtat cacagtcaga ggattttagc acaactattg
     6601 aaagactgcc ggctgctgat tataaggcga gtattaatgg ctattataag gatcgtaaga
     6661 ttaaagtcag caaggcctat gatggcaaga accatacact agatttgagg gttaccttta
     6721 agacatttac ggtaaccagc aatgtcagag atggcgagct ttatattgat ggcgagcgcg
     6781 tggaaacttt gaaggctggg cagcttcagc tggaagaata ccctgtgaca gaaatcgcaa
     6841 aggcctatat taaaaagacc tttcctgatg gcgagctaac ctccagcaag cattcccttg
     6901 ctcctgttgc tgagggctcc cagctagaga ttaacattga tcacctcttg actgaggaac
     6961 aggcgggaca ggtgttggtg gcagcctttg atcaattgct cacctatctc aatcaagggc
     7021 aggatccagc aggtctttca actgtttttg agcaaggggc taataatgct ttttacaaag
     7081 gcttgaagga ttccatcaaa gcaaaatttc aaactgatac cagaaaggct tctcggttaa
     7141 gcattccgtc tattttgtta agtaagctaa ctcaaattgg taagcagtct tatctagtgg
     7201 actttacagc tgtttatgat tttgtttacg ataaggaaac tgatcctgaa aaaggcacct
     7261 cagggaatgt tcgtcaagac ttgactggta agctgaccct gaaaaaatct ggggatagct
     7321 accttgttag tcagtctggt cctaaaaata ttacagttgc cagcgaaaaa aatcaggtca
     7381 agccgtctat tttcccagag gggctagtgg gaacctggat aggacatcgt tcggacatga
     7441 cctttacgat gatattggct aaggacggca gcatcacaac aaccattgga aacaaaaatg
     7501 ggaatggctc acagaccact aagtctgcta aaattaccaa ggtagaggaa aaaggagatg
     7561 gcttgttcct ctacactgta gctccagatg ctgatatagc agctcttgtt ccaggaggtg
     7621 gattgggtgg tgtcaatgtc aaatacgctt ttggtgtcaa atggagtgga gatgtcgcta
     7681 cgatagtggt ttggcagaca gcaaataatg cggcatttga ttacagtaag ccaatgcttg
     7741 gccctgacat gaaaaagcaa taagtacttt accctacaag ttggtctagc atttattgct
     7801 aggaggaatc agcataaaga aaaagcctct cttttaatct tttgtggtta agaagagagg
     7861 ctttttagta tagggctgac tgtatgagga gcaaccgatg taatcaattt agctgctgta
     7921 gtccttcttt aaagctttta gacggggcag tgaccctaat catctcttga gccaaggggt
     7981 gtctaagggt tagctgatga gcgtgcagca tgagacgctc cgctttttgc ctgctataga
     8041 ggggatcacc aattagaggg tgtttatgat gagcgagatg tactctgatt tgatgtgttc
     8101 gtcctgtctc taggcgacag ttgactaggc aggtctgatc aaaggcttgt aataaggcta
     8161 gatgggtgat tgcctcttgc ccatgcttac tatcaaccac acgcttgcgc ctatcgtggc
     8221 ggtgacgtcc gattggatcg cgataggtta ctgtttgctg ctctagctga ccttcgatta
     8281 gggcccaata atctcgctta atgtctcgat gctccaatag gcgatttaag atcggaagga
     8341 taaagggatt tttagcaaag agaatcgctc cactagtctc catgtctaag cgatgaacca
     8401 catagcaggt cttgccagta taggcagaga catggttgag caaggcgagc tcagtgggct
     8461 cattgccatg tgttttcatg ccctcgggct tgttgacaat gatgaggtgt tcgtcctgat
     8521 acaggcaatc cactaggcca ggcttaccca ttaagatgcc tttatcaggg tagtcttctt
     8581 ggtcaaattg tagcttgatg tgatcaccct gcttgacagg gctctgccag ttaatcagct
     8641 catcattgac ccaaacatgc tttttgatgc gcaagaaatg tctgatttta cggggaatca
     8701 atagcctatc ttctaataac tccttgacag ttgtcgcttg ataggggtta atgaaggaga
     8761 tctgaaagcc catctcaggc ttatttgctg ttgtcattga gccagtcatg gtatttttca
     8821 atcaaattga tggccatttg ggttgcaaga gttacagaga aagcctcggt tccctcgcgc
     8881 tcgtcactgg caacctctaa gcgtgtctca tcatagacag ccttgaggct ctctgctgac
     8941 agggtttctt taaaagcttg aaatttgttc atgatcatgt cctacctttc taaatgtttg
     9001 tgacaatgct attatagcat atttttcatc aaagctaatc atttgctcga tgatttgtgc
     9061 tgcgctaaca gcgtgattct tttgagaaaa aataagatta gctattgtga aattgtctgt
     9121 cttttattat actaagaata gtctgataaa tatattattt aaggacacga taacattggg
     9181 attatgaatc atttaggaga atactattga acaagccatt gataaaatcc tgtttgcttg
     9241 ctctattgac cttggccggc ttgaccagta tggcagcaca ggctgatgtc aacacttaca
     9301 accaaggtag gacatataac gatacaccct attattctgc ttatcatcac tactatgacc
     9361 acacgaggga tactgctgac aatggtattg ataattgggg tcgtctgaca cgctatcact
     9421 attacagaga gacctattat cagcttgagg ccgagcgtca gcagcttgtt aggacttact
     9481 tggagttgaa ggcttcatat gatgatcagg tggctcttag cagtcaacga ctacagcagt
     9541 accagtctgg ctggtctgat ctccaatcac gctttgagca gctcaggaaa accaatcctg
     9601 ttgtaggcgg tgattatcgg attgttgagc tagagggcaa ttttcaaagc tatcagacct
     9661 tgctgcagca gctttctatg gctgattttg tcagccagta caaagatagg ctggatacct
     9721 tgactagact tgatacagag cgagctaggc tcattgacac ctggtgggaa agtgatagca
     9781 attactcaga tctcaatacc aatctaacac tagtcaatgg ctatatcaag gagctgaatc
     9841 aggctttaca ggagcttctt aaggaccatc aaggtaaaat gacatcagat ctgcagacct
     9901 tgggtgaccg acaggccgag cttgctagac ggctgacaga tatagaaagc aggcctaaga
     9961 gacaggctac cagtcaacct cgtggttcac agacacattg gcgatcagcc cctagagctg
    10021 atgttgcctt gtggaatgaa ttgcgaaacg aaggagatta tgcttctgct acgacagaca
    10081 atgctttgcc attgcagcct tatcgagcgg acttaacagc tgttcatgat ctagaagcct
    10141 tgcaagcaca atctgataga gcacaccgct tgcgggcaaa ggaaattgtc tttacactgc
    10201 agcgttctaa cattagtcgt cagggcgata tagatttgtc aggagccatt acagcattta
    10261 tcaaagaaaa gcttctcgtc actccaaatg cgcgtggggt atcatctggc tttaggtggc
    10321 aaatgcaaac ctatgacaat gagcgcttaa ccatcactct aatgcctcaa tattatatga
    10381 ctgatgatca gtacaaggag tattacgacc atctcaaggc ttggacagct cagcatatcc
    10441 agtctaccga tacagaggtt gagaaaattg ataagattca agactatatc atgacaaact
    10501 accactatgc gaccggcaag gttggaggag tgacccgtac tggcatttct gtgcagacgc
    10561 catatgcctt tatcaaggac aaggaggctg tttgtcaggc ctatgcacag atgtttaagg
    10621 acatgggacg actagctgga cttgatgttc attatattca aggctatgga gacccagttg
    10681 gcggcttatc aagtctacat gcttggaata tcgtcaaggt tgatggtcaa tattatcata
    10741 ttgacctgac ttggaatgat actattgaca gcaccaatca caatcatacc tacaccctgc
    10801 gaggcaatga ttttatgagc aaaacacatt tgtggaatgc tgcctatgcg atctcagata
    10861 gtgactatgc tgcttatcct aggaggagct tcctgagata tgggacctat gcgactaact
    10921 attcaagaaa tacattttat ccaggataca gttatgctta ataatagcta ataccatcaa
    10981 aagccctaga aagcttgctt gattctttca gggctttttg atatgtcatg gtttttggta
    11041 taggattttg aaagaaattg ttataatagg ataaaatgct tatgtaacag gagaaaataa
    11101 aatgaagagt attagacgct atgatgtcaa tgaagagtgg gcacatactg gcttagtaga
    11161 ggcaggcgat ttttattttt taaattattg tgtaggaaat gtcggtcaag atattgaggc
    11221 tcaaattaac ggtgcctttg atgaaatgga gcgtcgtttg gggctggtag ggctgacgct
    11281 agaggtcgtt gttcaaatgg attgcttgtt tagagacatt tggaatgtgc cagttatgga
    11341 aaaaatcatc aaggagcgat ttaatggcaa atacccggct cgtaaatttc ttcaaacagc
    11401 ctttgctcat cagggtggtc cggacggctt gctatttcag gtagatgggg ttgcttattc
    11461 aaagcatatc tccgtatcct aaacaatatg acttggaggc ttagtagtat cataaggcta
    11521 tgacattttt agaattatta caaaagaaat tttttccaaa aaaataccaa gaaaaacagg
    11581 ccttaaagga aagggcagcc cagcatatgg ctgacaaaga ggctactact caggctactg
    11641 ccactgcttt ggccgatcag gaggcacagg cagggcagac tgagaggcaa tcagtccttc
    11701 aacgcagcaa gtcctatggg gtcaaaagga aaaatcggcc gatctggctt caaaggctgg
    11761 aggcgatttt gccatcgcag caaggtccta ttcgccgctt tcttcgtcgt taccatgttg
    11821 gtaaaatcct gctgattttg atgggtacct ttgtcttgct gctggggtct tacctttttt
    11881 acctttcaaa gacagctaag gtttctgact tgcaggacgc tcttaaggcg acgacagtca
    11941 tctatgaccg caagggagaa tatgcaggca gtctttctgg tcaaaagggg acctatgtgg
    12001 agcttgacgc tatttcagat gatttggaaa aggcggttat tgccacagag gaccgtacct
    12061 tttataccaa caatggtatt aatttcaagc gctttttatt ggctattgtg accgcaggac
    12121 gctttggtgg aggctcgacc attactcagc agttggctaa aaatgcttat ttgtcccagg
    12181 agcagagcat taaaagaaag gcgcgtgagt ttttcttagc acttgaattg accaagaaat
    12241 acagtaaaaa tgacattttg accatgtatc tcaataattc ctattttgga aatggtattt
    12301 ggggtgttga ggacgccagt caaaaatatt ttggtacctc agcagctaat ctaaccttgg
    12361 acgaggcagc aacccttgcc ggtatgctca agggacctga aatttacaat ccctattact
    12421 caatcgaaaa ggcaaccaac cgtagagata ctgttttgtc agccatggtt gacgctggaa
    12481 aaatcagcaa gcagcaggca caagaggccc aagctattgg tatggggaac cgtttagcag
    12541 acacctatgt cggcaagaca gatgattatc agtacccatc ttattttgat gctgttatca
    12601 atgaggctat ctcgcgctat ggcatctcag aaaaggatat tgtcaatgat ggctacaaga
    12661 tttacacaga gttggaccaa aattaccaag caggcatgca gaccaccttt aatgaggata
    12721 gcctatttcc tgtgtctgag tttgacggca gctcagctga ggcggctagt gtggctctag
    12781 atcctaaaac cggagctgtc agggggcttg ttggtcgtgt caatagcaca gaaaaccagc
    12841 cctttagaag ctttaactat gctactcaag ccaagcgtag ccctgcttca acgatcaagc
    12901 ccctagttgt ttatactcct gctgttgcag caggctggtc actggagcac gaactgccaa
    12961 acagcgttca ggattttggc ggttatcagc cgcataatta tggcaattac gaatcagaaa
    13021 caattcctat gtatcaggct ttggctaatt cctacaatat tcctgctgtt tcaattctgg
    13081 atcagttggg ggtggataag gcctttagct atggtgaaaa atttggtttg aagatgagtg
    13141 aaaccaaaaa ggagcttgga gtggcgcttg gtagtggtgt caccaccaat ccgcttgaga
    13201 tggcacaggc ctatgcagtc tttgccaatg gtggtgtcaa gcatattgcc cacctgatta
    13261 ccagaattga aaatgctaag ggcaaggtta tcaagacctt tacagacaaa accaagcggg
    13321 ttatcagtca atcagtggct gataagatga ctagcatgat gcttggaacc ttttctaatg
    13381 gtacagctgt taatgccaat gtctatggct atactctggc tggtaaaaca gggaccacag
    13441 aaactgactt taacccggac ctttccggtg atcagtgggt cattggctac acgccagacg
    13501 ttgttatcag tcaatgggtt ggcttcaatc aaaccgatga gcatcattat ttatcagatt
    13561 caagtgcggg cactgcctca gcaattttta gcacccaagc ctcttatata ttgccatata
    13621 ccaaaggaag ccaattcaag gtcgataacg cttacgctca aaacggtatt tcagcggttt
    13681 atgggattaa tgagaccaat acgcaagcag gtattgattc tcaatccatc attgatagtc
    13741 ttagaaagtc agccgaggaa gcttcaaagt ctatttcaga ggcagttgat caatctggtc
    13801 tcagagaaaa ggcgcaaagt atctggaaga gtattgttga ctactttaga tagcttgcga
    13861 aaatatctaa atcgtgttag aataatcact acggaggcgt tatggcacag aaaaaagcaa
    13921 gcctagcgtg tgtagaatgt ggcagccgca attattctat cgggattagt agcacgccta
    13981 gaccaacacg actagaagtc aataagtttt gcaaatattg taaagcatac accttacaca
    14041 aagaaacacg ttagaggaga gcctgatggg attcattagt gggattttta agcttttaag
    14101 ggatacaact tggccggatc gtaagcagcg ctggaaggac tttatttctg tccttgagta
    14161 tacagcattc tttacggtaa tcatctttat ctttgaccag ttgctatcaa aaggcatttt
    14221 atcattgatt aatttattct aagtcattgc aatgatgaga cctgttatga ttaaaattgc
    14281 ttggaaaagc ctaggctgaa acaatcgttt cggccttttt gagtgcgatg ggcaggttgt
    14341 actctgatag atgcaagacc aatagaccac ctactatgcg ggtgcgtaaa ggggttgata
    14401 gctaccgata gttaagggct atagcaagta gaaaggcttg cagctcagct gatccgctgt
    14461 tatgactaaa ggcattgacc agaaaggttc gttggcagcc aacaaagtgc tcttaccctg
    14521 ctatgagggg ctattaatgc gttgacagcc aatccttctt ctattataat gaaagtgtga
    14581 taacagcaat gcaaaggcca gcagaggctt ttttataatg aaaggaagta acatgttaga
    14641 ttcttttgat aagggctggt ttgtccttca aacttactca ggctatgaaa ataaagtaaa
    14701 agaaaacctt ttgcagcgtg ctcaaaccta taacatgcta gacaatattc tccgcgttga
    14761 gattcctacc caaacggtaa atgttgaaaa aaatggtcag gtcaaagagg ttgaggaaaa
    14821 ccgcttccca ggatatgttt tggttgagat ggttatgact gatgacgctt ggtttgttgt
    14881 tcgtaacaca ccaaatgtga caggctttgt cggatcgcat gggaaccgct caaaaccaac
    14941 ccctctactt gaagaggaga ttcgtgctat cctgttgtca atgggacaaa ctgttgatgt
    15001 ctttgatacc aacattaaag agggcgatat ggttcaaatc attgatggcg cctttatcgg
    15061 gcaagagggt cgtgtcgtag aaattgaaaa caacaaggtc aagctcatgc ttaatatgtt
    15121 tggctcagaa accttagcag aggtcgagct ttaccaaatc gcagagctat cgtcctgata
    15181 ggctcctaaa gctattattc ataccataaa aaataaaagg ctggcatcgg ctctctaaaa
    15241 taccgatgtt aggccttttt tgttggtctt ctacaaccaa gactcaaatt aaccaaaccc
    15301 taaaaagagt catttttcct tcgcttttta agtctctaac tgatcgccct agcttatttt
    15361 taatctagta atcgcaacag gtcaagagtt aaatgatatc gcgccgttat tgattggtat
    15421 agacaaaaat acgctcaaaa aaagaaaaaa ggataggtaa tatagtcctg gtttgcttga
    15481 tagatggtgg ttggcaacca accattcgag tactttcctt aactataaac tcctaatcaa
    15541 ttctagcgtt taaaaaataa gattattctt ggagggaagc aaagagcttc tctccttttt
    15601 gagttgtagc attcttgatc ctgatcttat aagcagagtc ctgtttgccg ggctgttgag
    15661 atgaataagg gcatttctat agtgattata tagtgttgca gatgtgtgta tggtttaagg
    15721 tctaaatacc cttcaagctt agttcttggg tagtcagttc ggattggctg gctgattttt
    15781 aagcctttaa tggcttagtg gtaagacaaa ccagattaca tttgctaaaa agtccctaag
    15841 gctacaatca ttttttgtga ctaatataaa aactagacct tttgggattt gtaataattt
    15901 ag
//
LOCUS       DARYMD010000045        15875 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYMD010000045 DARYMD010000000
VERSION     DARYMD010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15875
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(419..2830)
                     /locus_tag="TU818_001487"
     CDS             complement(419..2830)
                     /locus_tag="TU818_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0924287.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGMHKALNSSSKDNSIAYID
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVAHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELVAAQAYWNNKQGGKPSVIGGQPLPGQGDQPRPYDIPVNPI
                     HHPAGNLPSVGDPSLSFADKTFGELLDQLHGLDKKYRHVKEDGLIFEPTQVTLANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGITAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTGVQPKLAVEVSSLPMHAGNATYDTWT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPTKDQEPSAQDTAADGIEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLMLYDVTT
                     LQQIK"
     gene            complement(2845..3768)
                     /locus_tag="TU818_001488"
     CDS             complement(2845..3768)
                     /locus_tag="TU818_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL0924288.1"
                     /translation="MKRKWIHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSKVAVFEASKSLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLK"
     gene            complement(4095..5642)
                     /locus_tag="TU818_001489"
     CDS             complement(4095..5642)
                     /locus_tag="TU818_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0924289.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANANTYTTYARDNVVTATSQA
                     AEGFDFVATILDSNGRALEGKTVVLLDTTANPAKQVASAVSNSNGQAIFTQLPLNINL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPLYSKNVIDITVRNQDSEPLEGQ
                     TVTLKIRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKSSPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     AKTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSESNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMFYEIVINGVKIPKKASTGSDVSGFLTKAQIRTDNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKSSSNRNVAPKEGKKETKALPRSGESAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            complement(6267..7148)
                     /locus_tag="TU818_001490"
     CDS             complement(6267..7148)
                     /locus_tag="TU818_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL0924290.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGKTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMKEGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            complement(7313..8314)
                     /locus_tag="TU818_001491"
     CDS             complement(7313..8314)
                     /locus_tag="TU818_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0924291.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSVGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSACQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMSKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPRYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            8455..9627
                     /locus_tag="TU818_001492"
     CDS             8455..9627
                     /locus_tag="TU818_001492"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL0924292.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLTFDQADLWANYPKGVLSFL
                     QKAGHLIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFGLDVERLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGADKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEQALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDKVDSFIETVGKAYTKVIGYAPAFYLAEIAQGARLLSRK"
     gene            9631..11115
                     /gene="galT"
                     /locus_tag="TU818_001493"
     CDS             9631..11115
                     /gene="galT"
                     /locus_tag="TU818_001493"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL0924293.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            11125..12135
                     /gene="galE"
                     /locus_tag="TU818_001494"
     CDS             11125..12135
                     /gene="galE"
                     /locus_tag="TU818_001494"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL0924294.1"
                     /translation="MTVLVLGGAGYIGSHTVDWLISQREEKVIVVDSLVTGHRKAVHP
                     EALFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMADPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKAS
                     GS"
     gene            12212..13255
                     /locus_tag="TU818_001495"
     CDS             12212..13255
                     /locus_tag="TU818_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL0924295.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINTNGVEAHLLTLGATLQAFLVS
                     NEKQPKNIILGHDRPSDYLKNPLCAGQTIGRVAGRIKRGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTVDYLEVTFKRDILEADDHFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHNLYIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKSLYPAIVENNGFDTAFEIDQQAIGTTKPIAVLQDSVSHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKEGLAREGIAMEAQTLPDAIHHNQFGDIILKEGGTK
                     SYTICLAYEHLPD"
     gene            13556..13699
                     /locus_tag="TU818_001496"
     CDS             13556..13699
                     /locus_tag="TU818_001496"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0924296.1"
                     /translation="MIFDKDTNLKHKHRHQKFWYMGYYGDTAGKNLKTIAKYISNHYR
                     KIG"
     gene            14313..14474
                     /locus_tag="TU818_001497"
     CDS             14313..14474
                     /locus_tag="TU818_001497"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0924297.1"
                     /translation="MPYSNAKLEPTNKTIKDMKEQAFGFRNFKNFKVKIPNALNITKE
                     ETKFISSRA"
     gene            complement(15066..15404)
                     /locus_tag="TU818_001498"
     CDS             complement(15066..15404)
                     /locus_tag="TU818_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL0924298.1"
                     /translation="MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISI
                     LEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVFYLIRQSRVDILRIRSTKTDYLN
                     DLENLFNNIL"
     gene            complement(15394..15681)
                     /locus_tag="TU818_001499"
     CDS             complement(15394..15681)
                     /locus_tag="TU818_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEL0924299.1"
                     /translation="MATLIRDRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERV
                     VEEKDLPIKTAEQIRAESFLNELISELDEGYQDILAGRTKPANEVFSKYGL"
BASE COUNT         4623 a         3537 c         3115 g         4600 t
ORIGIN      
        1 aattgtacgg ctgctaacct ttttcctaac ccttttagac accaaaaaac tccccttatc
       61 gtttttagtg attgtttttc actgtccact ttaaagggga ggtctagcta ttaaaggcta
      121 ggcggttttg actggaggac tattaggtgt gaggttaatt ggtaaaaact ctttctgtgc
      181 tgccctcctt aggtcatata gactttcttg gaaccaaaac ccacatatag cctacagaga
      241 tccaatgctt taaaagctat gaggtgctaa gctgctgatc aagtcagctt ctctgactgt
      301 tgctgcaagc aaaagcctac taagcgatct taggctgtga ggcgtaagaa caggtcatca
      361 taccaatagc tttttgggga taagctgtga tttgtatgcc ttagctattt tatagtgttt
      421 atttgatttg ttgcaatgtt gtcacatcat aaagcattag gtgtcctttt tggtcataga
      481 atttgacacc ctctggcacg aaaataagat actccggttt aatgcctgct atttcagcta
      541 actgattgat ctgacgttca agagttgccc gatctaaacc ataattagga atatcgtcaa
      601 ataaagactt ggtctgctct atgccatctg cggcagtatc ttgcgctgac ggttcctggt
      661 ctttggttgg cttaatagtg ctttcagctg cgtctgaggt cttattgcct aataattctt
      721 gaaccttttg ccattcatca tgagataact catctttagt aatggttctt aaagagcgtc
      781 caccaactct aggaatgcta aaggaatcat tacgccaaac aaaggttcct tcagcaagaa
      841 cgtccttagg atcaaaaata tagccatctg gagctgcgta ccgacctgcc ttgatagctg
      901 cttggacctc ttcggcagag tgaataattt gccagttttc cattgaagta cgttgatcag
      961 ctggtgtgac attagcaatg actcctccag cttcatcatg atttgggtta gaccaaacat
     1021 caggacgagt attagggtgc tgcatgacat atttgatggt cgcaatctga tccttagtta
     1081 gccatgaata aggtacaaca tggatatgat cgatgtgagg aatgacaaaa gatgtccatg
     1141 tatcataggt tgcattacca gcatgcatcg gtaggctgga tacctctaca gctagctttg
     1201 gctgaacgcc tgtatcaaca atgtcataaa tatagtgttg cttatcctta agcatgagct
     1261 cttgctctgc aaaggcaatt tgtgttaggt ctaaatgctc acgatcatag aaatactctt
     1321 tgccatcttt tgtcatcatg taaccaacct taccgccatt ggttaccttg cgactgacat
     1381 gcttagcgtc aaaggacatg tctttaccgt ctgattgaac taatgccctt gcaatctcat
     1441 ctgcttgacc atgctcctgc agccattgtg caacctggtc aagctcctct tgctctagct
     1501 caccaaagcc catgtaatgg aaatgctcct catgcttagc tgtgatgcct gccttatcaa
     1561 cagaggaaat agatgcctta ctaaagacat aatgatcact cgtgtcataa ggcttgccat
     1621 ctaagccttt accataagcc ttaatctgat ggccaaggaa ttgatgtgta acctcttttg
     1681 cagtctggtc ttgagtagct ggctttggct tagctattgg actgccctgc gtttgacctg
     1741 ctaggtaacg atcagccaag gttatttcaa gggctgacaa ttgctcacga ggaataatat
     1801 ggtagtgatc tccatgagga ataacatagc caaaggcatt ggcaagggtc acctgagttg
     1861 gctcaaaaat gagaccatct tccttgacgt gcctgtattt cttatccaag ccatgcaatt
     1921 gatccaacaa ttctccaaag gttttatctg caaatgatag gcttggatct cctactgacg
     1981 gcaaattccc agctgggtgg tgaatcgggt taacaggaat atcatatggt ctaggctgat
     2041 ctccttgacc tggtaaaggc tgaccgccaa taacacttgg ttttccgcct tgcttgttat
     2101 tccaataggc ctgcgctgct actagctcac ttggggataa gtccttttta ggaatatagt
     2161 ggaagtgact gccatggggc actaaaaagg catctcccat gtctccaata acatctgtcg
     2221 ggctaaagat atagccatca tcagttgtat agcgtccttg acttcttgct tcgttaacag
     2281 ctgccacctc tgccttactc aagtgggcaa ccttagccaa gcctttttcc ttagcttcct
     2341 ttgttccctt ttcaacctgc tcagcaattt gctgcttggt acgaatattt ttacgcttgc
     2401 ttcctggctt tagataaaca taatacttgc catcaacctt gataatatag ccatctagaa
     2461 tctcgttaac aacatcagac tgtttaaact gataattggg gtccgtcatt aatagctctt
     2521 cactaagaat agcatcatag ggaaccttac cattgtagaa atggaaatga tcaccatgtg
     2581 aggttacata gccttgatct gtgattttaa caacgatttg ctctgcagag atcccctctt
     2641 ctgcgctgat ttgatccatt gttttttctt tggggagggc ttttttgcca tcctttgaat
     2701 caatataggc aatgctatta tctttagatg aggaatttag agccttatgc attccaaact
     2761 gatatgaagc agcattagta gccaataaaa tggccacagc tgatcctaaa acaatatgct
     2821 tctttttcac gttttcatct ccctttattt taagctttgg taaagagctt ccaaattagc
     2881 tctcaaattg tctagatagg acttgttgtt tttgggcgct gcctctagtg gactgagcag
     2941 cttgaccttt gctcctgctg ttttagctat cgccttagca attttaggat taacattatc
     3001 ctctgcaaaa atcgttttta ccttatattc tttaacaaag tcttgaattt cagttagttg
     3061 gcgaggagta ggctcttgct ctggcgaaat accagaaata cctaactgct ttaagccaaa
     3121 gcgttttgct agataagaaa aggctgtgtg ctgtgtgaca aaggttttag atgatgtctt
     3181 tttaaacttt ttagtgtact catcagccag ctcttttgct tccttttgga atgcttgagc
     3241 attctcagtg taaatggcct catgcttagg atctaaacga ctgagctcct tagcaatagc
     3301 gagtgcttct tcacctgcta aaataggatc tgtccaggta tgaggatcat acagggtagc
     3361 agggtcaatg ccatctgtca cctcaatatc ctccaaacca gtaacacgat ctaaggttaa
     3421 agatttggaa gcttcaaaaa cagcaacctt tgatttcttc aaattaggat ccaaatcatc
     3481 agcccaggcc tctagggtgt gagagtgata aacaaataaa tcagcatcgt aaatggcagc
     3541 aacgtcattt acagatggct caaaggaatg aatacctgcc cctgactgaa tcatccgaac
     3601 atcgtttagc tcaccagata ccgcctttgt catggcgtaa ataggataaa agctagtgac
     3661 gatcgtcatg cctcttgact gcttgctttg ctccttgggc ttgctacagg caacaagacc
     3721 tgaaaaaaga gcaagcaaca gtgttaaatg tatccatttt cttttcatat aatctccttt
     3781 gctcattaac cagttatgaa ccggttaatt ttaacagctt tagatgtatt tgtcaaattt
     3841 tttaataaaa aataaaagcc attaaaacga tggcttaatc agcccctaac ctgcttaacc
     3901 tttataagaa gccatagctc tatgataaac tgtggtctgt gacgcatgac ctcactgtct
     3961 gttatcttac tgttgcatga tacgtttaaa aaagatttag ccttcttttt ttagattgta
     4021 gaacggcgct gaacaatcac ttaaccgtca aaaaaacgcc ttgatagctg caagacgttt
     4081 ttacttattt ggttttagct agagcgacgt tttgtcacaa gaccgatgac agctgcaagg
     4141 cctattaata gaactcccat gaacgctacc atcggcgctg ctgattcacc agatcttggc
     4201 aaagccttag tctctttttt accttcttta ggggctacat tacggtttga cgaggacttg
     4261 gtttctggct tagcgacatt cttatccttt tcaggatcct ttggctcctt gcctaagggc
     4321 tttgtgtctt tagaatggcg ctcagactcg ctgagtttat tatcggttct gatttgagct
     4381 ttggttaaaa agccgctgac atcactaccg gtagaggctt ttttaggtat cttgaccccg
     4441 ttgataacaa tctcataaaa cataccgtcc atgagctgat tcacaaaggt tgccttacct
     4501 gattgatcag ttttgcctat tgccctgata gctccgtatc gatttttcag cacaacctct
     4561 tgccctgcca acttatttcc attggcatca taaacagtta ctatggctgg tgtcttagag
     4621 taaacaacag gctttgttcc tttaccgtcg acataaaaag cagcagcctt atgctcatta
     4681 gactcactcg tgcgaacagt atagccctgt agcttaccat caattgagac actgatatta
     4741 cgtgatagtg gtagtttggt aaagactgct tgaccatcag catttgtctt tgctgaagca
     4801 attgtcgtct tagcaccgtc tatcagagca gtcaagctta cctccttgcc tgcaacaacc
     4861 ctatcctctt tatctagggc agtgacaaca aaatgaaagc cttcctctag cggacttgac
     4921 tttccatcct cctgcttagg agtgtccttg gactgaggtg acgtacctga tgacgagctt
     4981 gatgaggtat caaggtaagc attaacagac atttttgtca tgacctgccc tatatactta
     5041 ccattaagct cataatgata aaaggttccg tccaacaaac gatccttgaa ggttaccttt
     5101 ccatttttat ctgagacaag acttcccacc agttgaccct gacgtatttt tagggtgact
     5161 gtttgccctt ctaagggctc actatcttga tttcggaccg taatatcaat gacattttta
     5221 ctataaagag gctcctttgt ccctgctccc ttagcgacaa agcttgctgc ctctttagat
     5281 ccagcaagac tggttctcac tgtatagccc ttggtttccc cgtcaacaga aacactcaaa
     5341 ttaatgttta agggtaattg agtaaaaata gcctgaccat tgctgttaga gacagcagaa
     5401 gctacctgct tagcgggatt agctgtcgtg tctaacaaga caactgtttt tccttcaaga
     5461 gcacgaccgt tgctatcaag tatcgtggca acaaaatcaa aaccctcagc cgcttgcgac
     5521 gtcgcagtga caacgttgtc tctggcataa gtcgtatagg tattggcatt ggctgccaag
     5581 gccaagctag atataacagt aaccgttaaa agactgactt ttttcaatga ctgtttcttc
     5641 ataaaaaagc tcctttattt tgattaacta gcctagtttt aatgggaaat atccccttga
     5701 taccctttct gaggtgatag gaacagcagc aatctctctt agcctatgat gcctaagctt
     5761 taaagctaag ttttcaaagt ccacctaagg ggctacatgc cacaacaaaa agcatcagat
     5821 gaacagacat ctagaggcaa cagccgatct aagataatag ttagtagcca ttttagctac
     5881 tctcaaggct gtcgccgcag tgatgatgtg attgtctatg ctttttaata aaacttaact
     5941 agttaagatt tttgtgctgc tatcctatca aataaccccc gccaagtcaa caacaatgct
     6001 cataccacag caagcaaagc attttgatga tgactgaaca gccaaatcag ccaagcccca
     6061 ggcagcaaaa aagaggattc aaaccaaatc ctctctctac taagcctgct gctgttaacg
     6121 tatcatgcta aaggcaaatg gtatagccac gctgatatga aggtctgatt aacagctacg
     6181 acggacacgc ttgttaaggc taccattgct aatcacacta ggtcatatcc tccaccgtat
     6241 aagaatgact aacttcatta ttcagattaa cgatatacct gcaggtgctg aggaagtacc
     6301 ttgacagtga ttggtaaggc ctcaccctca tcaccgtcca cattgataga tagctgtcct
     6361 tccttcatgg caatagtggc ctccttgaag gtttgatagc caagtgtttg atctgaagcc
     6421 tcaactccct tcaataggct aggaagggcc ttcaccgttt ctaatagatt gctatccttc
     6481 agatagataa ggtgcagcaa accatcgtcc acacgtgcct ctggcaaaat ccgctcaaag
     6541 cccccgattg aattggtcaa gccaatcaag agtgttgtgc tgttgatttc ttttgttttg
     6601 ccatcaatat ctagctggaa ggtatagctt ttatttttga tcagctgctt aaagcctgac
     6661 ataaaataag ccattttccc aaaggtcgtc ttctcctcag gggcaacatc attgatcgcc
     6721 tctgggagcg tccctatggc aacaacattc ataaagtaag catcgttgac cttaccaata
     6781 tccagaggac tggttgtctc aaagcttatc tgattaatcg cttcctctgg gtctaacgac
     6841 atgcccaagg cacgtgccaa atcattgact gttcctagag gaaaaaagcc aaacttaggg
     6901 cgatagtcct gctctgcaag cccgctgatc ccttcattga ctgttccatc acctcccatg
     6961 acaaagacac tgtccagccg ctgctgggct gcctcatgag caaaccgttt ggcatctcct
     7021 cctttttcag tgtgcttaac gtcaacatca tcaaaatacg aagctagttt atcataggct
     7081 aaggcttcat attccttggc tttctcacca cctgagctag ggttaacaat caatagggct
     7141 tttttcattt atgatatcct acattttcta ttatatttca cgactattat aatcattatt
     7201 caaaacatcg tcaaataata ctcactatgt cattagtcag tcttaaagct tctaatatgg
     7261 ttgccgtcta gtgtttcatt ttactgaact ctttacccag ctagctcaat gcctaaccaa
     7321 tcgtgctgtc tcttaaggtc aactctgtcg ccaatatcgt catggtcttg acacgttctg
     7381 ggttaaggat attcctatta agcacatcaa cagccatacg tcccatatcc tctgtaaata
     7441 cagtcacact agaaagcgca ggaaagacct gtcttgttaa aggagtatcg ttaaaggaga
     7501 taagctcaac acgctcaggc accgcaagcc ctctttcttg gagagctctt agagcaccta
     7561 ttgcaagggt atcattagca ataaaaaatg ctttaggcaa atcatcacct agctcctcaa
     7621 ttgcctgtgt cataagctca tagccagatt gtgctgaaaa aggaccgata tagacatacc
     7681 tcggctgata aatcccatgc tcagaggcat aatttttata ggtgcgaaag cgctggtcca
     7741 ctaaagcttc tctaccgtca gttgtctttt cctcaccagc aatcatgcca atgctataaa
     7801 tccctttgct cataaaataa tcaagaactt tcagcactgc attgtcaaag tcagttgtga
     7861 cacaggggtg gcccaattca agcgtgtcac tatcaacaaa caccaaatgc tgggataagg
     7921 cttcaagctc cttgatttga caagcgctaa actttccaat agcaataatc ccggcatggt
     7981 catctgaaac cctcaaaatg tcattgttga aataacgaac aatatcataa tccaattcat
     8041 aagctctttt ttcaatgcca atgcggatcg cataatagta gaggtcattg agctcctctt
     8101 cttgagaata ccattgaaca atagctattt ttagctttga tttagggcta ttcgtcgctt
     8161 ttaaatgctt ttggtagccc agctcatcag caattgtgag aatgcggtgc tttgtctctt
     8221 gaccaacaga caagctttgg tccttattta aaactctaga aacagttgca ggagaaacct
     8281 ttgccagagc tgcaatatcc ttaagcgtta ccatatcaaa ccttctttct gatttcttct
     8341 agtatatcac aagcattttc aaaagcaata tttagtaaaa ttttagtaaa aatgttgacg
     8401 agcagcttag cgaagcgtaa aatcaagcta tcaacatcgt taaaggagcc gctaatggat
     8461 atcgcgcaac ttaagcaaag ctttactgac gtttttggca aggagccaga tgctgtcttt
     8521 ttctcaccgg gtcgcatcaa cctcattggt gagcacactg attacaatgg tggacatgtc
     8581 tttccagctg ctatcagtct gggaacctat gggctggccc gcaagcgtga ggatcagcag
     8641 ctgcgctttt tctcagcaaa ttttgaagag gctgggatta ttgaggttga cttaaatcag
     8701 ctgacctttg atcaggctga cctttgggct aattacccta agggagttct ctcctttttg
     8761 caaaaagctg ggcaccttat tgatacgggc tttgagcttt acgtttttgg caacattcca
     8821 aatgggtctg gtctgtcctc ctcggcatca ctggagcttt tgacaggtat tgtggcacaa
     8881 gagctgtttg ggcttgatgt ggaacggtta gatctgatta aaatcggtca gcaagctgaa
     8941 aatcacttta tcggggtgaa ttcaggtatc atggaccaat ttgccatagg catgggagct
     9001 gataagcagg ctctatacct tgataccaac accttagcct atgaggctgt tccgcttgac
     9061 cttggtgatc acgtgattgt catcatgaat accaacaagc gccgagagct agccgattca
     9121 aagtataatg aacgccgagc agagtgtgaa caagcccttg aggaattaaa tgcccttctg
     9181 gatattaaag cactggggga attagacgct cagcgctttg atgagtacag ctaccttatc
     9241 aaagatggta aacgtctcaa acgcgctcgc cacgctgttt tggaaaatca acgaacactc
     9301 caagcaagac aggcccttga agcaggagca ttggagcaat ttggtcgtct gatgaatgct
     9361 tctcatgtat ccttggagca tgattatgag gtcacaggcc ctgagctgga cacactggtc
     9421 cacaccgctt gggagcaaga aggggtccta ggggctcgca tgacaggagc aggctttgga
     9481 ggctgtggca ttgctatcgt ggctaaggat aaggtagata gctttatcga aacagttggc
     9541 aaggcctata ctaaggtcat tggctatgct ccagcctttt atctggctga gattgctcag
     9601 ggagcacgac tactttcaag gaaataagat atggcaagct taatagacac ctttgtaagg
     9661 aaggtgattg aacacagcga ctacacatca gaggacgcta tttatatccg caatcgggtt
     9721 ttagcattgg ttggtgagaa ccatgtctgg caagaaacct ccttaacagc cttaatagct
     9781 ctcaaagaag cattggttga gctagctgct gaaaatggca aaataggcag gcttcctgaa
     9841 gaaaaggact gcttaggagc tgaattaatg aacatgataa cccctattcc aagtgtggtt
     9901 aatcgtcgct tctgggatac ctatgcacaa tctcctcaac aggctatctc agatttttac
     9961 cagcttagtc agctaaatga ctacatcaaa acagcagcaa ttgccaaaaa catctccttt
    10021 acagtgcctt ctcaatatgg tgatatggct attaccatta acctatcaaa gcctgaaaag
    10081 gaccctaagg ccattgcagc cgctaagaag gctaaggcat cctcttatcc aaaatgccag
    10141 ctttgtatgg aaaacgaagg ttatcaagga cggattaacc acccagcccg agctaatcat
    10201 cgcattatcc gtatgagctt aggcaatgag gcttggggat tccagtattc accctacgct
    10261 tattttaatg agcacagtat tatttttaat actgagcatg tgccaatgac aatcagtaca
    10321 agcaccttta gacagctcct tgatattgtt gatatcctgc cagactattt tgtcggctct
    10381 aatgctgatc tgcctattgt tggcggctct attttgaccc acaaccatta tcaggccggt
    10441 cggcacgttt ttccgatgga aatcgcaaaa caagacaaac gctttacctt taaaggattt
    10501 ccagacatac aggctgccac tctcaactgg cctatgtcag ttatccgact gcgcagcagc
    10561 aacaaagatc agctagttca attagcagac acgattcgac tggcttggcg tcattattct
    10621 gacgacagtg ttgatatcgt cgcttatacc aaccaagagc ctcaccatac catcacacct
    10681 attgccagaa aaaaagaagg gcagtttgaa ttagacttgg ttctacgtga taaccatacc
    10741 tctgagcaat ttccagacgg tgtttaccac ccacatgccg atgtgcaaca cattaagaaa
    10801 gaaaacatcg gccttattga ggttatgggg ctagctattt taccaccgcg cctcaaagag
    10861 gaattggttg aggtcaaaaa atatatcctc aatcaagcca atcaaatcgc agactaccac
    10921 aaggactggg ctgatcagat cacattacga ccagatctct cagcgataac tgttgatgac
    10981 attatccaag aagaggtcgg ctctgtcttt gttcgtgtcc ttgaggacgc tggcgtctac
    11041 aaacgtgatc aagaaggtca agcagccttt atgcgttttc ttaagagcat tggcattgaa
    11101 gcaattgaag aataggagga aaaaatgact gttctagttt taggcggtgc aggctacatt
    11161 ggatcacata cagtggactg gctaatatca cagagagaag aaaaagtcat tgttgttgat
    11221 agcttggtga cagggcaccg taaagccgtt cacccagagg ctctgtttta caaaggagac
    11281 ttagcagaca aagcctttat gcgtcaagtc tttagggaca atccagacat agacactgtg
    11341 attcactttg ctgcctcttc cttggtcgca gaatcaatgg cagaccctct gaaatacttt
    11401 gacaataaca cagcaggtat gattaagctg cttgaggtca tgagagaagc caaggttaag
    11461 cgcattgtct tttcatcaac agcagccgtc tatggcattc caaaaacagt ccccatctta
    11521 gagtcagcgc ctaaatgccc aatcaatcct tatggccaaa gcaagcttat gatggaaacg
    11581 ataatgacct gggccgacaa agcctatggc atcacatttg tggcccttcg ctacttcaat
    11641 gttgccggag caaagccaga tggctccatc ggtgaagacc acgagccaga aacacattta
    11701 ttacccatta tcctacagac tgcacaggga gtgcgtgagc aggtgatgat ttttggtgat
    11761 gattatgaca caccagatgg tactaacgtt cgagattacg tccatcctat cgatttagct
    11821 gatgcacaca ttttagcgat ggcatacctg cgtcagggca aaccatcaca ggtctttaat
    11881 ctagggtctc aaacaggctt ttccaatcgt caactgcttg aagccgctcg tcgggtaaca
    11941 ggacaagcca taccagccaa aaaagctgca agacgtcccg gtgatccaga caccttaatt
    12001 gcgtcatcag aaaaagcacg caaggttctc aattggaagc caagctatga cgatattgac
    12061 aagataatcg catcagcctg ggcctggcat accaagcatc caaaaggata tgacgataaa
    12121 gcaagtggca gctagtccct caagacagct accacagcaa gtagtcagcc tcccttaatt
    12181 catacaccta tactaatagg agaaacaaac tgtgaacatt tatcaagaca tcattgaata
    12241 catcgatcaa gtgccagtca cccagctaag actgattaat actaacggtg ttgaggctca
    12301 cctattgaca ctaggagcca ctctacaggc ctttctagtg tcaaatgaaa agcagccaaa
    12361 aaatatcatt ttgggacatg accgaccaag tgactaccta aaaaatcctc tttgtgcagg
    12421 gcaaaccatt ggccgagtag caggtcgcat aaagagagga agctttcagc tagagcagca
    12481 aagggtttgt gttgacacca atgaaaatgg gcattgcctg catggaggct tcaagggctt
    12541 tcataagctt cattggcctt atgatacccg ccaaacagtt gattaccttg aagtaacctt
    12601 taaaagggat attttagaag cagatgacca tttcccaggt gacctgaccg taagcattac
    12661 ctaccgtcta gacaaccata atcgtttaag cattcacttt aaggctcata gcatgagagg
    12721 cactagccta ttcaatccaa ccaaccatgt ttattttaat ttagggcaaa cacaagactt
    12781 aaccaatcac aacctataca tcgcagcatc acataggatt gaaacagata atgagctaat
    12841 cccaacaggt caaaagctag cagttgacca gacggtctat gattttagat caataaagtc
    12901 cctctatcct gctattgtcg aaaataatgg ctttgatact gcctttgaaa ttgatcagca
    12961 ggctattgga acaaccaaac ctattgctgt cttacaagac agcgtcagcc atgaccaaat
    13021 cagcatctac tctgaccgaa acgcactcgt catttatacc atggacagta tccaagatgg
    13081 cttgtatttt ggaagagatc agggcaagga gggactggct cgtgagggga tcgctatgga
    13141 agcacaaacc ctgcctgatg ctattcacca caaccagttt ggtgacatta tcctcaaaga
    13201 aggaggcacc aaaagctaca ctatctgcct agcctatgag catctgccag attaacataa
    13261 gtacagccaa gctttaatga aataacaaga ccttgatttt tttgaattgc accccaaccg
    13321 ttagccaaaa actctaacaa gcgaggatca gttcattcat caaggtcttt tcctcttttt
    13381 atctataggc gttacaaagt agatatagga acatcatacc aaatatgtgg aatgctaaga
    13441 gcttatcatc acaaagcgaa tacatgttcc gactacatct atgcattagt aagtcttttt
    13501 cctaaacgaa gtgttgccag ctttatgaga tacttaaaag tataagagca gcctaatcat
    13561 ttttgacaaa gacaccaacc ttaagcataa acataggcat cagaaatttt ggtatatggg
    13621 ctattatgga gacacagctg gtaaaaatct aaaaacgata gccaaatata tttcaaatca
    13681 ctataggaag atagggtagc aaaccaactg acatcatttg agaccattga tccatttaca
    13741 ggccaaccaa ataagaaaaa gtaacctttt gattgaactc ccgctcggaa aagtggagcg
    13801 cgagtattca atgacctcgt tatcctcgac cgatgagagc agcttatagt cacagtataa
    13861 agaggctgga acagacaacc tcttttgatt gacaataagt gtttgatagc attgtatggg
    13921 attactttca catcattcag cacctgggtc gagctttgat gaccgccaga attgatagcc
    13981 attatgaagg gctttgagca gccatttctg ctttatcgaa ccataaaata tcattgatga
    14041 ctgctccaaa aggacagtca taaactgtct gatcagcgct tctagtcacg aacctttaag
    14101 caaaccttaa tactcaaaaa aggtaagtca gaaaatactt gatttctcag atgagctgtg
    14161 gaattaccac gacctttacc agctcttgct ctttcatttt caaaaagtgg gtaaccgagt
    14221 ttttcgggct gattgaagag ctttaagctt ggtcaatcat cacgttttaa ccgtcctcaa
    14281 aatctttttg aaatacaaac cctacatcac aaatgcctta ttccaatgct aaattggagc
    14341 ccactaacaa gactattaag gacatgaaag agcaagcctt tggatttagg aactttaaga
    14401 acttcaaagt caagattccc aatgctttaa acatcacaaa agaagagaca aaatttatct
    14461 cttctcgtgc ttagctatca gtcacccact gcagttgaca ttgagccaaa ttatagagcc
    14521 attttcgtag aaagcacaga aaaaacaccc atgaggtaaa ctcttgagtg ctttgaaacg
    14581 ttgatataat gcgatatatt aacgttttga ggcacggaga ctgcgtctcc tttgcagccg
    14641 tattcgtaag cgactaaagc cgcaacgact acgtcaattg cgtcgccagt tctttcaaaa
    14701 aagaaaatac cccatggtaa cccatgaagt attgttctgc tgtattgtag ctggttctta
    14761 acgttttgag aactgactag ctttacgagc tttcttaaga cctggttttg ggtgacaaaa
    14821 accaaatatc tgtaaaagct tatcaaatca agctttcaaa actcattttc attaaatata
    14881 agcactttta acccaatcct acaaataata gattaccatt agattaccaa aactcagttt
    14941 tcggagctta tgtagttgag aaaatctcgt atttactttg cttttatata tccactttat
    15001 actatcatcc cgtcataaca gagcatgatt aaatagttac ataaaaaaca atacttactc
    15061 tatcattaaa ggatattgtt aaaaagattc tctaaatcat ttaaataatc agttttagta
    15121 cttctaatac gaagaatatc tacccttgac tgacgaatta aataaaatac tatgaaatgc
    15181 ttactaggaa tcatccttag ctggccttca ggaaatagtt tacgtcctac acgatcgtca
    15241 aaatcaacat aaccttcagg ggatatctca agaatagaaa tagctgactg caaagattca
    15301 ataacttttt gagcgcttga gtgcgaaaat tctgttaaat agtagttata gatttcatct
    15361 aaatcttgtt ctgccttatt tgaaatatag atatcataag ccatattttg aaaatacctc
    15421 attagctggc ttcgtacgtc ctgctaaaat atcttgatac ccttcatcaa gctctgatat
    15481 cagttcattt aaaaatgatt cagctctaat ttgttctgca gttttaatag gtaaatcttt
    15541 ttcttccacc acccgttcaa caaatagatt aagagcatct ggaacactaa tatttttagc
    15601 ttctaaaata cgctttgctt cttccatcat ttccgtattt actctaaaat tatactgtct
    15661 atctcttatt aatgtagcca ttatagtctc cttaattgcg ttatccttat gtataacaag
    15721 attataacaa atcaatagtg acttagcaat ataaagcaat ttgcaaactt gccattagtt
    15781 tactaaaaat aagtatgttt tcggaattta tcagttgaga gatgctaaat gtaatcactt
    15841 atcaactatt tttaaatatc tacaataaca gaaaa
//
LOCUS       DARYMD010000046        15640 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYMD010000046 DARYMD010000000
VERSION     DARYMD010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15640
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..1034)
                     /locus_tag="TU818_001500"
     CDS             complement(<1..1034)
                     /locus_tag="TU818_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0924300.1"
                     /translation="MASLIPFEFKKLLRRQSVFGAIVVVLLAVGGLFYQHFFNGQISG
                     SSADQVHGRAAVAINQQIAEKHTGYLSDDLISRILNDYAKNQSDLKKKGVYSVVSHYA
                     ISHLVPKSTDKLIAINSTDKSLTFDNVHLKSREELGSALPLKELKLGNFAPWNQLFDV
                     TNSTYLLVVMLCLYITAPLFSGESSKKMNSILLTTVFGRGKLTLAKLAVSIAVSTLVF
                     AIASGLVFAVFATYFGFSGWDTSLQLNLYWIDPVINIMAFPEKMTLGIAFVYLLVFQY
                     IGLIFMTGIHALVSSLTKSPLTTFGISALIVYAPVFLMGIFPEGLMNKLLTFVSVQTF
                     GTQELLLKLA"
     gene            complement(1040..1894)
                     /locus_tag="TU818_001501"
     CDS             complement(1040..1894)
                     /locus_tag="TU818_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924301.1"
                     /translation="MLLILDNISKSYGSKKVLSRISAQFTPGLYGLLGANGTGKTTLL
                     NIISQFTVPDSGEISLNHQQQPKNFYQNIGFLPQQFNYYQQFSGLEFLLYMAALKNVK
                     RKKALVEADRLLKLVGLYDVRKKKIASYSGGMKQRLGIAQALINDPLLLILDEPTVGL
                     DPKERVKFRNIISDLSEQKIIILSTHIVSDVEAVAKEVILLKHGQFIEKGSVDQLVQT
                     MIGKVWEIPVATESAPAFLTDYAVVNEKIVKNNRILRVVSDESPCYQANPVSPTLEDL
                     YIYHFRKE"
     gene            complement(1961..2161)
                     /locus_tag="TU818_001502"
     CDS             complement(1961..2161)
                     /locus_tag="TU818_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL0924302.1"
                     /translation="MNTKTIEQFSTMTADMLAGVEGGWGYRWRCTDGYTSAWHLLRDT
                     AQENADNHMILYPGTVCRVYNA"
     gene            complement(2534..3271)
                     /locus_tag="TU818_001503"
     CDS             complement(2534..3271)
                     /locus_tag="TU818_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0924303.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLL
                     ANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
                     IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
     gene            complement(4022..4327)
                     /locus_tag="TU818_001504"
     CDS             complement(4022..4327)
                     /locus_tag="TU818_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL0924304.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQAHDMKAGGLISISAHQFYHLEAATNCKYLQIEMV"
     gene            complement(4329..4667)
                     /locus_tag="TU818_001505"
     CDS             complement(4329..4667)
                     /locus_tag="TU818_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL0924305.1"
                     /translation="MSLIRKIPTSTVIDLKAEVPIEEDQILSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSLGDAMVNVLSGVVDITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            complement(4695..5450)
                     /locus_tag="TU818_001506"
     CDS             complement(4695..5450)
                     /locus_tag="TU818_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL0924306.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLVQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAIIEQL
                     RDTINVNVSPLQLDAWRQLLVKSGFTAVNYSYGNMTLMSPLGMIKDEGVVAAIRIMLR
                     GMKKENRKQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            5711..6166
                     /locus_tag="TU818_001507"
     CDS             5711..6166
                     /locus_tag="TU818_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL0924307.1"
                     /translation="MEYDKLPSWKDLPDLELYLDQVLLYVNQVTQLSQATDHKLLTAS
                     MINNYVKHGYIDKPIKKKYQKKQVARLIAISILKNVFPIQDISQVLTSLQAASSSEVL
                     YDTFVNYWNNGLTQSTPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            6150..6800
                     /locus_tag="TU818_001508"
     CDS             6150..6800
                     /locus_tag="TU818_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL0924308.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            6910..7814
                     /locus_tag="TU818_001509"
                     /pseudo
     CDS             6910..7814
                     /locus_tag="TU818_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            complement(8167..8442)
                     /locus_tag="TU818_001510"
     CDS             complement(8167..8442)
                     /locus_tag="TU818_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924309.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSETIEEL
                     NHYIQEKGGQLIETASDKVEASKVAANACGHSAAKAIKGTLEEAIKI"
     gene            complement(8865..10415)
                     /locus_tag="TU818_001511"
     CDS             complement(8865..10415)
                     /locus_tag="TU818_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL0924310.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKVAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQGLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
     gene            complement(11086..11646)
                     /locus_tag="TU818_001512"
     CDS             complement(11086..11646)
                     /locus_tag="TU818_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0924311.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(11624..12493)
                     /locus_tag="TU818_001513"
     CDS             complement(11624..12493)
                     /locus_tag="TU818_001513"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL0924312.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKPFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKQQLPF
                     VLDPIMADKGSMYAQLTSQHLSAMRLLAQAAQLILPNVTEACLLADVPYFGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATETVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEVELGSLGAAFR
                     GLLEEKDDIKTID"
     gene            12585..13856
                     /locus_tag="TU818_001514"
     CDS             12585..13856
                     /locus_tag="TU818_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL0924313.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGEKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELREALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRHHILLETPTYHRMEQLATSLGLPYQTIERDVNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKKEKESIVRLAEQYQVYIVEDDYLGDFASHSELPLHYYDTQHRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQMRQFFNNRAHNLLDFLQKHLPNLAYQLTPQALIIQLDKAFNRKKLLKPHHTQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(13892..14230)
                     /locus_tag="TU818_001515"
     CDS             complement(13892..14230)
                     /locus_tag="TU818_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924314.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(14330..15418)
                     /locus_tag="TU818_001516"
     CDS             complement(14330..15418)
                     /locus_tag="TU818_001516"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL0924315.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYAPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDPSVSFD"
BASE COUNT         4832 a         3442 c         2720 g         4646 t
ORIGIN      
        1 taggccaatt ttaataataa ttcttgtgta ccaaaggttt gtacggatac aaatgttaac
       61 agtttgttca tcaaaccttc tggaaaaatt cccattagaa agaccggtgc atatacaata
      121 agagcagata taccaaaagt ggttagagga gacttagtta gagatgaaac tagtgcatga
      181 atgcctgtca taaatatcag gccaatatac tgaaacacca ataaatagac aaacgcaatg
      241 cctaaggtca tcttttccgg gaaagccata atgtttatca ctggatcaat ccaatacaaa
      301 ttgagttgta agctagtgtc ccagccgcta aaaccaaaat aggtcgcaaa gacagcaaag
      361 accagaccac tagcaattgc aaataccaaa gtactgacag ctatgctaac tgctaattta
      421 gcaagagtca atttaccacg tccaaaaaca gtcgtcaata agatagagtt catcttttta
      481 gatgattccc ctgaaaataa aggagccgtt atataaagac aaagcataac aacaagaaga
      541 taagtactat tggttacatc aaacaactga ttccaaggag caaaattacc taacttcaac
      601 tctttcaaag gcagagcgga ccccaactct tcacgtgatt tgagatgaac attgtcaaat
      661 gtcagagact tatcagtgct attaatagcg ataagcttat cagtagactt aggcactaaa
      721 tgagagatag cataatgtga taccacacta tatacaccct tcttttttag gtctgattga
      781 tttttagcat aatcattgag gatacgacta atcagatcgt cagataaata acctgtatgc
      841 ttctcagcaa tttgttggtt aattgctaca gctgcacgtc catgaacctg atctgcagaa
      901 gagccactga tctgaccgtt aaaaaaatgc tggtaaaaaa gaccacctac agccaataag
      961 accactacaa tcgcaccaaa taccgactgt cgtcttaata attttttaaa ctcaaagggt
     1021 atgagagatg ccatagaatt cactcctttc taaaatgata aatgtagaga tcctctaatg
     1081 ttggtgacac aggatttgcc tgataacaag gactctcatc gctcacaaca cgtaagatac
     1141 gattattttt tacaattttt tcattgacaa cggcatagtc agtcaaaaat gctggtgcac
     1201 tctctgtagc aacaggaatc tcccatacct tgccgatcat tgtttgaact aactgatcaa
     1261 cacttccttt ttctataaac tgaccatgct ttagaaggat tacctccttt gcaaccgctt
     1321 ctacatcaga tacaatatgt gttgatagga taataatttt ttgctctgat aaatcactga
     1381 taatatttct aaattttaca cgttcctttg gatcaagtcc gactgttggt tcatctaaaa
     1441 ttaacagtaa aggatcgttg ataagtgcct gagcaatacc caatcgctgc ttcataccgc
     1501 cagaataaga agcaattttc ttttttctaa catcataaag acctaccagc tttaataacc
     1561 gatcagcttc tactaaagcc tttttacgtt taacattctt caaagcagcc atataaagaa
     1621 ggaattctaa accggaaaac tgctgataat aattaaactg ttgaggtaaa aagccaatat
     1681 tctggtaaaa gttttttggt tgttgttgat gatttaaact aatttctcca ctatcaggaa
     1741 ctgtaaactg actaatgatg tttaataaag tcgttttacc ggtcccattt gctcccaata
     1801 acccatacaa gcctggtgta aattgtgcag aaatacgact caacaccttt ttacttccat
     1861 aagatttaga aatattatct agtattaaca acattgtcat tcctcctaag taaaaaccca
     1921 gggaacagca ccacttcgct gctccccaga tgattaacca ttaagcatta tatactcgac
     1981 aaacggtacc aggataaaga atcatgtggt tatcagcatt ttcttgtgct gtatctctta
     2041 atagatgcca tgcacttgta taaccatcag tgcatctcca cctataaccc caaccacctt
     2101 caacgcctgc aagcatatca gcagtcattg tactaaattg ttcaattgtt tttgtattca
     2161 tatcgaatac ctccttataa tgattttatc tagctacagt ctcgacaaac ttagtgtagc
     2221 gctttttaaa gcaacgacac tcaaaaatct tgaatggttc ttattttgtc gtgaatggtc
     2281 aatttttctt ctgaaattac cagttaagat catatggata cctttcacga gctatatctt
     2341 tttctctctt ttcttatgat ataattgatt tttgcatgta catcatatct ctgagcatca
     2401 ttagaaacca actgttaccc ctttttctta gttttgacta aatatattta taataaatat
     2461 cccttaaggt aaatggtatc aacgaggttg attaaaaaac aaatgatggc ttccacatgg
     2521 cattctttta ctgtcaatgc aaagccttaa tagacgcctc aagtgctttc atttttagtc
     2581 ttgaaaccat gcaagactgc ccattcttga aatagagtaa acgcttatca cgatcaagaa
     2641 acgaaacatt gtaaggattg ataacataag aacgatgaca ttggactagt ctggaatctt
     2701 gcttaagaac ctctgaaaga aagccataaa attctattcg ctcgttttga gaatgcaaaa
     2761 tcaacttgtg aggagtacta gaggtctcaa tgaacaatag gcttgaaaaa ggaacctgca
     2821 cctgagcctt agccgttgca aaaataaata agccctctga ggttacattt tcttgctctt
     2881 cataagcata tataatggct ctttcaatcc tatctgagaa atgtttcatt gacaattcct
     2941 tatcgataaa atctagagca gacacctgat aacgaaaaga aactggcata agctcagaat
     3001 gtgtggtgac aaaaacaatg agggcataag ggtcacgctt tctgatctca cgagcaacag
     3061 ctaagccctt tttctcatca tttcgaattt gaatatcgag aaagaaaagc tgatgcctgc
     3121 ctctctctgt aacatttgcc agaagctggt agggctttcc ataaacttca aaacgatcac
     3181 aagtccagtg atgcttatcc aatatctctt gaatcttcat ctcaagccta aactgttggc
     3241 ctagatcatc ttcgagaata aaaatattca tttagaacct ccttattgct ttagcttatc
     3301 gtttttttag gagactaaag cagctttttg aacaagtgat agctagaacg ctctccttca
     3361 tgaacagtat ctttttagca tcaccattaa aaccatgacc gttaagctta ttaactaaag
     3421 gttgtcaatg acttctaacc aacttgtcat tgcagcgttt tcaataggcc ttagcgaatc
     3481 acgcgcctca aacaattttt ttaccacaga taatatacta gcacgagccg caagtcatac
     3541 ctctttgaga gagagctctt aacgactatc acttttgttt gacaagtcat cagctatcaa
     3601 tccacacact gatctccttg cacagacatt ctaacacaaa gctagggagc agggagttaa
     3661 aatcttaaat ggtactgatt atgtcttaaa tggtaaataa ggaaaactaa caatggctag
     3721 tcaggttact gaggctatct gatgattagc tgcttgtagc tataccttct ccaagcaata
     3781 agtttctaga attattggta acaaatacat taggtatccg ggatattctg tcatttattt
     3841 tatcataaaa acaatctttt tatcatcaaa acaggtaatt gttattatta ttaatcactt
     3901 tgagtgattt gaagtaagct agatcttcag ctaaacctta tgacactaaa cacaaaaagc
     3961 cccctaaggc agctaaaaca ccagcctagg gggcaagatt caagagagtc actctatact
     4021 tttagaccat ttcaatttgc aggtatttac aatttgttgc agcctctaaa tgataaaact
     4081 gatgagcaga gatactgatc aatccgcctg ctttcatgtc atgagcctga tccgtaagac
     4141 taaccagcaa ccttccttct aagacaagca ggagcttacc ttcagggctt gattcgttac
     4201 taatcgtctc tccctgatac atggcatata aaacaacaga ttgcttaaag cctaggcttt
     4261 gatgaagcga acgactagct atttggtcat catgatacct tactaattct aataaatcag
     4321 ccaacatgct aagcctccgg ctttacaaca actaaaagca tctggaaggc ttccttagca
     4381 aataagctat gaggaatatt agcaggcatg atgatcgtct cgccagcagc tacctcataa
     4441 caggcttctc caatagtaat gtcaactact ccacttaaca cgttaaccat tgcatctccc
     4501 agtgatgaat gacgaccgat ttcttgtcct ttatctaatg aaaacagggt tatgcccaaa
     4561 tcttttcttt gaactagtgt tcgacttaat atttgatcct cttcaattgg cacttctgcc
     4621 tttaaatcaa tgactgtgct tgttggaatt ttacgaatca atgacatgtc acttctcctt
     4681 taccattatt ctagttattt ttgacttaca gcggcaatat aacacagctt tcttccagtt
     4741 ttgttgaaga aatgacgcat ctttaaaaac tgctttcgat tttctttttt catgccgcgc
     4801 agcataatac gaatcgcagc gacaacccct tcatctttaa tcatgccaag cggggacatg
     4861 agcgtcatat taccatagga gtaattgact gctgtgaagc cactctttac cagcaattgt
     4921 ctccaggcat ctaactgcaa tggcgatacg ttcacattaa tcgtatctct tagttgctct
     4981 ataatagcct ttgtttcatc agcttcatag gaaacatcat gcgttagtag gcgaccaccc
     5041 ggctttaaaa cacgccaata ttccttaagt gctttttcct ttgcagcatc attcaacatg
     5101 gttagcatag cttcgttaat aacgatatca aagctattat ctgcaaaagg cagcttcaag
     5161 gcattagctt gggtaaggtg aatatagtct tgcatttgtg ctgcctcaat agcctttctt
     5221 gcctccgcca gtaccttggt atccaaatct actgctgtaa tatgacactg ataagtctgc
     5281 gccagctcaa tggaggtcgt gcaacggttg caggccactt ccaagacctt gcaatcactc
     5341 gaaaactctc cttgctgaac cagccaattc gtcgcctcaa caccgccagg ccgtagtcgt
     5401 ttctttccca gtcgagctaa aaactggtga ccaacttctt tttgagacat cacatgccct
     5461 cctatttgct ctgctatata tcatcactta gaataaacta actgttaaca aattgatcaa
     5521 taaatgatta ctacaactat atcacactta aagcatatcc tcaatgaagc ttaagcattt
     5581 ctgatgattg tttttatgat aaatcataga attggctcat atttcttgtg ctatacgacc
     5641 ttttgacttg ctattatttt ttaaataata tataatctag ttatcaaaac tagataaaga
     5701 ggttttagta atggaatatg ataagctgcc cagctggaag gatttacctg atttggagtt
     5761 atacttagat caagtgttac tctatgtcaa tcaggtcaca caattgagtc aagccacaga
     5821 ccataagcta ctgactgctt caatgatcaa taactatgtc aaacatggct atattgataa
     5881 acctattaag aaaaaatatc aaaaaaagca ggttgcccgc ttaattgcta ttagcatttt
     5941 gaaaaatgta tttcctattc aagatattag tcaggtcttg acgagcctac aagcagcctc
     6001 cagctcagag gtcttgtacg atacctttgt caactattgg aataatggcc ttacccaatc
     6061 aacgcctgaa attattagct atgcttgtca aaccgtcaag gactatcagc acacaatgaa
     6121 gctttcaaga gaaatggagg ataccaagca tgaaccaaac ctttaaacaa agtctcccac
     6181 tatcagttaa tgaagaggtc gcaaatagtg tgacacacgc tattggagca gctgctatgc
     6241 tgatactgct acccatcact gctatttact cttaccagac ttatgatctc aaggctgccg
     6301 ttggagcatc tatttttatc atcagcttat ttctcatgtt tttatcatca acgatttacc
     6361 attccatgtc ctatggaaca actcacaaat acattttacg tatcattgat catagcatga
     6421 tttatattgc tattgctggt agctatacac ctgttgcctt atccttggtt gagggcttgt
     6481 tgggctatgt gattatcata ctccagtggg gaatcacact ttttgggatt ttgtataaaa
     6541 tttttgctaa aacgattaat gaaaagttca gtcttgcgct ttacattatt atgggctggt
     6601 tggtcgtttt tatcctgccg gtgattatcc aaaaggccag tctgccattt ggaatcttga
     6661 tgctactagg tggcttatcc tatactgtcg gcgcaggctt ttatgctaaa aagaagccct
     6721 attatcacat gatctggcac ctttttatcc ttttagcctc tgctttacag gttattgcca
     6781 ttattttcta tatgctgtaa aaagtagctg ttgctacttt ttaaacgcga gcgcttgctt
     6841 acccccagac acctggcttg attcatgcta taataaaggg cagtaaatag ttgaagggat
     6901 caaagcaata tgaaaacggt acatattttt tacaatccta attcaggaaa accagaaaat
     6961 gacctggctg aaaaggtcaa gcattatctg attcaaaatg gtttttctga agacaaggtt
     7021 cagattatta cccccaaaaa tgctgatcaa gcctttcaat tagccaaaaa atcctcacag
     7081 gatcatattg atctagtcat tcctctaggc ggagatggga cacttaataa aattattgga
     7141 ggtgtttatg aaggtggtgc tcattctgtt attggactcg taccgtcggg cactgtcaat
     7201 aactttgcaa aggccttaaa cattccactc cagctaactg aggcacttga gacgatttta
     7261 tctggcacga ttaaaaaagt agatatttgc aaggtaaaca agggctatat gatttctagc
     7321 ctaaccttgg gtctgcttgc tgatattgcg gctaatgtga ctacagaaga aaaacgaaaa
     7381 tttggccctt ggccttttta aaggatagta ttaagatact aaaacgaaac cgcacatatg
     7441 caattagctt aattagccat catcatgttc ttcacttgaa aaccaaattc ttattgatta
     7501 ccacaaccaa tactatagca ggtcttccat cgttttcacc aggtgcacaa gctgacgatg
     7561 gcttgtgtca agtttacacg atgagccagc tatcatttct gaaatgcttg cgccatatta
     7621 gagactttag acggggggat ttttccaagg taaaggagat tagccatttt caagctgatt
     7681 ctctaaagct attgccacaa tatcagcgtc aatcagccat tcctagaact cgcattgatg
     7741 gcgataaggc tgatgatctc cctgttgaat tgaaggttat tccaaaagcg atttccatta
     7801 ttgttagcca gtaaaaaagt gccctagggc actttttgat atagattcat ctccaagctg
     7861 agttttagaa aactaagcta tagctataac gttagctgtg gcttcttctt gctggcttgc
     7921 agtactcttt tcttgtctta acagctagct ctttcataat atcggcttta acaaagaagc
     7981 tatctgacta gtccgatctt ctattctcag gacaaacagc gagaaagggg attttctttg
     8041 aatcctagag aaccttagct atctctgtgt ctcattgtaa gtgcagctct attgactgat
     8101 gccagctata gcaataagcc cagtcgcata ttataaagga ttatcaggcg atttagcttg
     8161 acactcttat atctttattg cttcttctaa ggttccttta atagctttag ctgctgaatg
     8221 accacaggca ttagcagcaa ccttagaggc ttctacctta tcagaggctg tctcaataag
     8281 ttgtccaccc ttttcttgga tataatggtt caactcctca atagtttcag agccttcctt
     8341 taagagctct ttctttttgg ctgaggataa gcttaaatat gtcacagcaa ttgctgctga
     8401 accaagaagt aatcctaagc cgattccata gctttttttc atcatcaacc ctactttcta
     8461 tgaccttcct taatcatctt tttagctaat tttacagctg gtactactaa aagcaccaat
     8521 tgtaaaagat ccatatactt gatttttcgt cgttttttca ccatgtgcta tttccttttt
     8581 cttgtttgca ccatacaatc gtcttttatt gcgcagtgcc agagactgcc tgattaggca
     8641 gcgtaagcta agaactatca gcgtgtcaga ctagtctaga tacagctaag cactagcttg
     8701 attacgataa tacttaccgc taggccataa gctcagctat catcaaatct aaagtgacaa
     8761 cgctttttat ttattatatt gtcattttac taaaatacac aattatcgtc aatgcttttg
     8821 ctttaggcag caaaaatgcc caagataaag accttggaca tctgctacaa tgacgttaat
     8881 tgattgaaat cccaaatatc agttacccag ccctcataaa actccggctc atggcaaacc
     8941 atcaaaatag agcctttata gacttgcaag gcgcgtttta actcctcctt agcatctaca
     9001 tctaaatgat tggttggctc atctaggatt aaaacattgt gctcacgatt cattaagaga
     9061 caaaaacgaa ccttggcttg ctcaccaccc gagagcccct gaatctggct ttcaatatgc
     9121 ttagaggtta gaccgcaacg agctaaggct gcccgaacct ctgcttgatt taaagcagga
     9181 aaagcgtccc atactgcttc tagtggcgtt tgacgcttaa cacctgcagt ttcttgctca
     9241 aaataaccaa gctccacgaa atctcctgtt tccacctctc ctgacagtgg ctgaataatg
     9301 ccaagcaggc tctttaggag ggttgactta ccaataccat tagcaccgat aattgcaact
     9361 ttttgatgac gctcaaatgt taagttcaag ggatcttttg ttaggggtct gtcatagccg
     9421 atgacaagct cccttgtttg gaaaataaag cggcttggtg ttcttgcttc cttaaactca
     9481 aagcttggct ttggtttttc tgcctgaagc tcaatgattt ccattttatc aagcttcttt
     9541 tgacgggaca tagccatatt gcgagtagct actctggcct tattacgatt gacaaaatcc
     9601 tgtagctctg caatctcttt ttgctgacgc tcataggctg cctctagctg agcttttttc
     9661 atctcataga cttccttaaa ctgatcgtaa tttccagaat acctaaccaa attccgatta
     9721 tcaacatgat aaacaatatt aatgacatca tttaaaaaag gaatatcatg tgaaatgagc
     9781 acaaaggcat tgtcataatg ctgtaaatag cgctttaacc actcaatatg ctcagcatca
     9841 agataattgg tcggctcgtc cagcagcaaa atatctggct tctccagtaa cagcttggcc
     9901 agcagaatct tggttctttg ccctccagat aaggaggtca cttctgtttc catcccaaaa
     9961 tccataactc ctaaggcacg cgcaacctca tcaatcttag catctagggt ataaaagtcc
    10021 ctgctttcaa gacggtcctg tagctctccg acctcctcca ttaaggcgtc gacatcagct
    10081 gtctcctctg ccatagacat gtaaatggca ttgatacgct cctctgtttt gaatagctca
    10141 tcaaaggctg tcctaagaac atcacgcaca gtttgaccag gttctaaaac ggtatgctga
    10201 tccaaatagc ctgctgtaac atactttgac cattcaatct taccagcatc aggctgcaag
    10261 tgaccagtaa caatactcat aaaggtggac ttgccttctc catttgctcc tactaatcca
    10321 atatgctcgc cctttaaaag acgaaaggaa acatcttcaa aaatggcacg atcaccaaat
    10381 ccatgactta actgcttaac ttctaatatg ctcatgatta ctttccttta ttgtcatcaa
    10441 aaaagccgtt aaaacggctt acactctctc aattatggca aaaatgcagc cttttgtcaa
    10501 tgaaggctga aaaagcctac gtcatacgca tgaaagattt ttagcaagaa cagaaggttt
    10561 tttgcatttt aatgttcagc tatttcaaat atgtcttatt attttataaa ttttactata
    10621 gggaaagcct tgaaagtgcc tgctttaatt tatactatca ttcggaaaga actgtttcgc
    10681 tcgtttgttg tggaaagccg ctcacaacaa agacatagag agtctatgac aacaagagct
    10741 acactttagc aagtcttgac cgacatgctt tattgcccag tctaattcat taaaaagcga
    10801 acaggtctag ctttcggaat ttcagaaaac taggcctgtt catttgttct attttgaggc
    10861 agccttttgt ttcggcctcg tctgtttcaa ggttttcaga tcgaacttaa ggacaaaaaa
    10921 cactctcctg tatcagctaa ccttatcatt cattataaag gaaaatgatt tctaatacaa
    10981 ggaaataccg ttatttcatt aaaaataact aaaaatagtt tgtcaaatca ttagttatta
    11041 ataggcttag ataacaaaaa tgatgatact gctagcaagg ttagctcaac caagcctatt
    11101 actcgcttct tgctttttta ctgcctgcct taattgctta aaaacagggt ataagagagg
    11161 cacagcaata acggtcacaa gggcagtacc aagactgcca ccaattttgc caagtgctgc
    11221 ccacaaagca acagacaggg gtaactgggc gccaaaataa gcaatcaagc tatatttcac
    11281 aagattcatg actaattttg ctgctgctgc taataagcca attgctacaa taatcatcgg
    11341 tttatcaact gatttcagaa gtttctcata aatcacatga agcaggtaac aaaccactaa
    11401 ggcttcaagc actgttatcc agaccacagc cgcatagcca ttaatcatat caaacagtcc
    11461 tagaccaatg gctgccacca aagctgccct tctagcacca tacaataaaa cagccaccac
    11521 cactaaggca ttccctaggt gaataaattg ggctccaact ggaatacgca gcagctcaac
    11581 cgatataaaa ataagagcag caaataggct aagctcgatc tgatcagtca atcgttttga
    11641 tgtcatcttt ttcctccaat aatcctctaa acgcggctcc caagctgccc aattctactt
    11701 cgtaggcaat tccaagtgaa agctctcgat ttagcgcaac agtagccgct aatgacttgt
    11761 ctaagaagct aataaccata tccaacaact catcaatagc aagcctgtga aaatacccag
    11821 cgctaacaat agcagagaca agatcacctg tcccatagaa atgataaggg taccgttttc
    11881 caaaatgata gctaaccgtc tctgttgcct tttgataata agcaaagccg atgtgctgat
    11941 catcaaagga tataccagta aggacaatct ctctaggtcc tagtgtagct agcttagaca
    12001 atagcctctc caaatcctct ctgctatagg tctccccaaa ataaggaaca tcagctaaca
    12061 aacaagcttc cgtcacattt ggcaatatca gctgtgcagc ttgagcgagc aatctcattg
    12121 ccgataagtg ctgcgaggtt aactgcgcat acatgcttcc cttgtcagcc ataataggat
    12181 ctagcacaaa gggaagctgt tgctttttga tgtaatcaag aataatcaaa gcatcatcag
    12241 gacggtacaa ataaccggaa aaaaagccat caaaggcaag acccgcttga gaccaagtcg
    12301 tcaaaaatgg ctttagtccc tctgacgtgc tctgaatata aggcgtctta gcaattgcag
    12361 tgtggcttga taacaaacag gttggaagaa tggcctgttc aatctggcaa gccgccataa
    12421 tgggaatact agcagacaga gcaaccttgc caactccgac aatatcattt gcaacaataa
    12481 cacgttttaa caaccaataa gctccttcat ttcttttttt actattgtaa gaaaatcctt
    12541 gatgagatac aataaggata gatttcatct gtatggggac acttatgaca agtaaatatc
    12601 aacaaatcat tgcagaccta gagttggcca tgcaatcaaa ccaattcaaa aagggagaga
    12661 aactcccttc tattagacaa ttaagtcaac agtatcactg cagcaaggat acagtgcaaa
    12721 gagcactttt agccttacaa tacaagcgcc tcatttatgc tattccaaaa agtggctatt
    12781 atgtgcttgg taaaattgag gaaaagcagc attcctttga gctaagcctt gaggattata
    12841 atcagttggc ctatgaggac tttcggctct gtctaaatga agccctagac ggtaaagatt
    12901 ctgatttatt taactactat cataaggctg agggacttga ggagctgcga gaggctttgc
    12961 tgccttattt ggctgataat gggatttacg ctaacaaaaa tcagctgcta attacctcgg
    13021 gtacacaaca ggccctttac attttagctc aaatgagatt tcccaatggc cgccatcaca
    13081 ttctccttga gacaccgacc tatcaccgaa tggagcagct agcgacttcc ttaggcttac
    13141 cctatcaaac cattgaacgt gatgtcaacg gtatcaatct tcatcagctt gaaagcatct
    13201 ttaaaaccgg acaaatcgct tttttctata ctatttctcg attttcaaac cctcttggcc
    13261 tctcctacag caaaaaagaa aaggaaagca ttgttcggct ggcagagcaa taccaggttt
    13321 acatcgtaga ggacgattat ctaggggact ttgcatcgca tagtgagctt ccgctacact
    13381 actacgacac tcaacaccgg gtcatttatc tgaaatcatt ttcaatgagc gtctttcctg
    13441 ccctgcgcat tggagccttg cttttacctg atgatctcaa ggaaggcttt ttgttacaaa
    13501 agtcaatgat tgaccttgat accaacctga tcatgcaaaa ggcactagca ttatatttag
    13561 caaatggtat gtttcaaaaa aacctaaagc aaatgaggca atttttcaac aatagagcgc
    13621 ataacttact agattttcta caaaaacacc ttcctaacct agcttatcag ctcactcctc
    13681 aagcactgat tattcaatta gataaagcat tcaatcgcaa aaagcttctt aaaccacacc
    13741 acacccaaat catctcaaca agaaaagcaa ggtatatgct tctaacaatc agtcctgata
    13801 tgccatctaa gctgctcgac ttgttttcag tgacacatga aaagacccaa gaatagctca
    13861 ttgggtctca gtgtcacaaa aatgtcaata gctatttgat ttgctcgaat cgtaaatgaa
    13921 cactaatgct atcgccgtaa ccgtttctct ccaaatctct ttggagccgg taagcaatat
    13981 aatgctctgc aatagtcatg tagcctgcgt caatcagacg attttcaaca agtgattgaa
    14041 tcatattaat cgtcggacgc tccgcctgca cctcttctag atcaataaca acctttttag
    14101 ttacctgagc tagatgctgt ctccagctgt catcaatcac ataaactgtt cttgctgcct
    14161 tgatcaaagc ctgataaatc ttatccggat caaagtctgc cagctgaccg tcacgcttaa
    14221 taatttgcat aagagcgcct cttttcattt agtttcattg cttacattca ttatgcaaat
    14281 gttttcatca tttgtcaagc tattaggctc ctatgcctct tagggattat cagtcaaaag
    14341 aaacactagg atcaaataaa ttgtcctgtg ctggtcggac aagcccacgc tcgtgcaagg
    14401 tctctgcaat ctgaacagaa ttccaggctg cgcccttgag cagattgtca gataccaccc
    14461 acatgtgaat gcccttttca acatctaaat ccttacgaag ccttcctaca aaggtctcac
    14521 gactgccaac agcattaacg gcctgtgggt atcgttgcac tccggtatcg tcctctaaaa
    14581 cagcacccgg aaattgtgca atcgcctcct taacagcttc gatagtagct actgccttgg
    14641 tttcaatgta gatagattct gaatgggctg ataaaacggg tatacgaaca caggtcgcag
    14701 acaccttaat cgtatcgtcc tccatgattt ttttcgtttc atttgtcatt ttcatctctt
    14761 cataggtgta gtcattttca gtgaaacgat caatctgtgg taaagcatta aaagcaattg
    14821 gataatgtct cttgtcacca gctgacggta aaacacttgc ctccacctcc ttaggagaca
    14881 agccctggtt aataacctgg tcatactgag ctagggtctc acgaatcgct gattgaccag
    14941 cacctgaaac agcctgatag gtggaaacaa taatacgctc aagaccccac ctttgacgaa
    15001 taggctccag cgctatcatc atttgaatcg tagagcaatt agggcaagca acaaggcctt
    15061 gatgtgtatc aagagcgtga gcatttacct caggaacaac aagtggaaca gctgggtgct
    15121 gacgaaaata agaggtattg tcaaccacaa cagcacctgc cgcaacagca taaggggcat
    15181 attttgcaga aacattgcct cctgctgaaa aaagggctag atcaatgcct tggaaggctg
    15241 cttttgttag ctcctcaaca acaaaatcct ctcccttaaa tgagaggatt tttcctgctg
    15301 aacgtgcaga cgctaataat ttaatagctg aaataggcag acttgactcc tccagcatct
    15361 taatcatttg ctgaccgaca gcgcctgtcg ctccaaccac tgctactgta taccccatag
    15421 atcgacctca ctttaactga tgatattgca aaaaatgata ttggacctat tatagcctat
    15481 ttcatcacaa aagaaaagca agctagaagc cagaacaaac gcatgaagaa aatcatttat
    15541 tgaaaaagtt gtgaaaatag caaaatatcc attttagagt attttgacag agtgtttcct
    15601 gaatttttat atttttcctc tataaacttt tcttgaaaaa
//
LOCUS       DARYMD010000047        15190 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYMD010000047 DARYMD010000000
VERSION     DARYMD010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15190
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(262..465)
                     /locus_tag="TU818_001517"
     CDS             complement(262..465)
                     /locus_tag="TU818_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEL0924316.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVVGGLTCAVGGIKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKASS"
     gene            complement(482..736)
                     /locus_tag="TU818_001518"
     CDS             complement(482..736)
                     /locus_tag="TU818_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL0924317.1"
                     /translation="MNTTLMKQFNIIDADKLAHIEGGKNNWQANVWEGGTAAVSGWGL
                     GTAICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            complement(1478..1774)
                     /locus_tag="TU818_001519"
     CDS             complement(1478..1774)
                     /locus_tag="TU818_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0924318.1"
                     /translation="MLTQEEILNKVYNLILDPTLTSEERVILVRFKDRVGESSNFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            complement(1781..2029)
                     /locus_tag="TU818_001520"
     CDS             complement(1781..2029)
                     /locus_tag="TU818_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL0924319.1"
                     /translation="MNMTLMKQFNIIDADKLAHIEGGGKGICKFVMSGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            2289..4445
                     /locus_tag="TU818_001521"
     CDS             2289..4445
                     /locus_tag="TU818_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL0924320.1"
                     /translation="MTLFYKRTFVSQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYVFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            4456..5814
                     /locus_tag="TU818_001522"
     CDS             4456..5814
                     /locus_tag="TU818_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL0924321.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLALLLTFLILFSCFVYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINSLSQQISDYEELRSAIINQSDSLSSNNPHQATLDAY
                     LSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIKASKSGIVQLNSAFEGKISIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSESVSLLKKNQVVRLALDRHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            5914..6045
                     /locus_tag="TU818_001523"
     CDS             5914..6045
                     /locus_tag="TU818_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL0924322.1"
                     /translation="MDKPTRQPKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLK"
     gene            complement(6167..7501)
                     /locus_tag="TU818_001524"
     CDS             complement(6167..7501)
                     /locus_tag="TU818_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0924323.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRL
                     LGFFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVSRLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNDSMSIVR
                     SVYQSVFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEDI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(7501..8250)
                     /locus_tag="TU818_001525"
     CDS             complement(7501..8250)
                     /locus_tag="TU818_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0924324.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
     gene            complement(8877..9080)
                     /locus_tag="TU818_001526"
     CDS             complement(8877..9080)
                     /locus_tag="TU818_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL0924325.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCIVGAGQAIINGL"
     gene            complement(9097..9354)
                     /locus_tag="TU818_001527"
     CDS             complement(9097..9354)
                     /locus_tag="TU818_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL0924326.1"
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSG
                     ALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TU818_001528"
     CDS             complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TU818_001528"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL0924327.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEEFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHCLVAID
                     DCLVQDQLTQAIVNHVTQLLDRYRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMVYVSCNTSTLARDLVPLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKPQQ"
     gene            complement(11039..12007)
                     /locus_tag="TU818_001529"
     CDS             complement(11039..12007)
                     /locus_tag="TU818_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0924328.1"
                     /translation="MTEKDKKDRDKVVSLQHYRQADAEDDMLFGHETEFFSDDLEALL
                     NSMDNQLLSDLEHFAGDRAYDLIKYLAFDEDCQHQAWLASKPMGWVNLEERPYLSQKF
                     ELAMLYKQNGLYEKALHHLLEIHQYDEGDHLGTRYEILALYVLKSDFTMAEAFYDSKD
                     YHRGDLLMEVPLMVGALLAEREELADDILANLAETVPDFVAIVRQKAFPIDDILAAGA
                     LESYEPNSLSSIYLAFFNILPLLMTAQYYLQHYVQEFFEGAEGELTFLEELDLPLSKV
                     NLFNQYGIHTLEDFSAWTTQELLDIPGVGKQMIARLKRLGVIFSQE"
     gene            12071..12847
                     /gene="recX"
                     /locus_tag="TU818_001530"
     CDS             12071..12847
                     /gene="recX"
                     /locus_tag="TU818_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL0924329.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDSLTVTEDTIVTFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYIRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQHKLPSKALTDKIIQGLLNKGFSYDLAKGIVSQLSLEQDSQHIEDLLDQEFDK
                     LLRKYSRRYDGYQLKQKLYQALYRKGYDSDDITTKLNDYF"
     gene            13080..13613
                     /locus_tag="TU818_001531"
     CDS             13080..13613
                     /locus_tag="TU818_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL0924330.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            13863..14174
                     /locus_tag="TU818_001532"
     CDS             13863..14174
                     /locus_tag="TU818_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL0924331.1"
                     /translation="MAFQATKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVNQQGIETILLPHEM
                     Y"
BASE COUNT         5007 a         3376 c         2397 g         4410 t
ORIGIN      
        1 atatgacagg ctacaggagt atcattcttt aaatgttaac aattgctaaa atttcgatat
       61 taggtctatc aatatcataa tataaaggat aaaaagaaac attaagttgt catgagctaa
      121 aaataacaaa aaaaagctat ttatcgttga tatatcaaca atgtcattat ttttatctaa
      181 acctctcaca gatctataga taaaataaat ttgaaaggtg aaaataacta tagtaaatat
      241 atatttcaga ttcatatcat attatgatga agccttatag gctaaataac cacaaacagc
      301 tgcacttcca actcctccga taacagctcc ccaaggtcca atcctacttc ccaactttat
      361 acctccaaca gcacaggtca aaccacctac tactgctgca ccggcagggt tccctccaca
      421 aatgtcgtta agttcttctt ctttgatttg ataataatga gtcataaaaa acctctcttg
      481 attaaaatcc acctgttgct cctgttactc ctgcccacaa tgatacgcca aatttggctc
      541 caatgtaacc acatgctccc ataaatggag caccggcacc acttgcagca caaatagctg
      601 tccctaaccc ccagccacta acagcagcgg taccaccttc ccaaacatta gcttgccaat
      661 tattctttcc accttcaatg tgagcaagct tgtcagcgtc tataatatta aattgtttca
      721 ttaatgtcgt attcatcgtg aatacctcct atatttattt tttgtctgct gcaactgaca
      781 aacccagtat agcagataaa caatcgcttt cagtatttaa gtcttaaaat gtcgtcgaaa
      841 cgtcttgaat ggtaatacga aaaccgttaa caccaattca gtgaaaattc ctaataccca
      901 taacaaatat gagaaagctg tcttaattgc ttcaaaagct gagtttcctc ctttgacggc
      961 tgaaggctct atgctgtaat gacaaatagc ccaatcttaa atgactattt tatttttcca
     1021 gatagcaata catcatcaac agctgatgaa aataatacat ttgtggcctc agcttactaa
     1081 cttaagcctc tagaaataag gaaaagcaac tgatttgata gctaatagcg cagataatat
     1141 ttcttttcca agctcaataa gactcaaaaa taagttcttt gtaagaaaaa ataaatcact
     1201 aaccaaatga gataagctta ttgcccttgc aattatctca agctacttct tgtccgaaac
     1261 caccctagat agttaactac cacaaaacaa taggtatcag ctttaaactg atacccattg
     1321 ttatatcctg cgattagcca atcaactcaa tcgttactta ctttaccttc agctagccat
     1381 ctcacaaaat agcattgaca accttttcat gtcatttggc ctattgtgac tcaacaaaac
     1441 aataacgcca atacaacgat aaggtatgag cgttttatta tcgcctaata actcccaatg
     1501 atattaggcc tctacctagc tgtttatcac attctttgta agtagagatt tctttataga
     1561 atttagccat ttctacactc attgtttcaa ctcttatctg cttaacagct aattgacgca
     1621 gagattcaga tagcatcatc acttctctgt caaagttact tgactcccct actctatctt
     1681 taaatcttac cagaatgact cgctcttctg atgttaaggt tggatctaaa attaaattat
     1741 aaaccttatt tagtatctct tcttgcgtca acatacccaa ctaccctcta taccctggat
     1801 ggaaataacc acctcctaaa gaggatatcc aaccattaac aataacatct ttagttgctt
     1861 caaaattact tttagtaaca atatagcccc attcgccatt gctatatcgg caggcatacc
     1921 cattagaacc agacattaca aacttacaaa ttcctttgcc gccaccctca atgtgagcaa
     1981 gcttgtcagc gtctataata ttaaattgtt tcattaatgt catattcatc gtgaatatct
     2041 cctatattta ttttttacct gttgcaagca acaaacccag tatagcagat aaataactgc
     2101 tttcagtatt taagtcttaa aatgtcgtcg aaacgtcttg aatggtaatg tcgcaactga
     2161 ttaaaaaaga gtgttaatat cattattccc atttaagacg tttcaacgac tattcaagac
     2221 tagctcagtt tttttctgag cttttgtggc acaatagagt cgttacaaca gagaaaggaa
     2281 gccaaccaat gacactcttt tataaaagaa cctttgtatc acaaatagat gccagagatt
     2341 gtggcgtagc tgctctagcc tcaatcgcaa ggtattatgg ttcagattat tcattagctc
     2401 atttgagaga attagcaaaa accaataagg aagggacaac agccctcggt attgtcatgg
     2461 ctgctaagga aatgggattt gaaaccagac ccattcaagc ggatatgacc ctctttgaca
     2521 tggcagacgt gccctatcca ttgatcgtcc atgtcaataa agaaggaaag ctacagcact
     2581 actatgtggt ctacaaatct aaaaaagact atcttatcat tggtgatccc gatccaatgg
     2641 tcaaggtcac aaaaatgtcc aaggaacgct ttgcttcaga atggacaggt gtcaccatat
     2701 gtcttgctcc taagccaaat tataaaccac ataaagacca aaaaaatgga ctattaggct
     2761 tctttccgct tatttttaaa cagcgaaccc ttatatttta tatcgtgtta gcttctgtct
     2821 tggtaacggt cattaatatt gctggttcat actatctcca ggggatttta gacgagtata
     2881 ttccaaatca gctgaaatct accttaggga ttgtatcaat tggtctcatc attacctata
     2941 tactccagca gctaatgagc ttttctagag attatctttt aactgtcctt agccaacgtc
     3001 ttacgattga tgtgattctg tcctatatcc gccatatttt cgaattgccg atgtcctttt
     3061 ttgcaacacg tcgaacaggt gaggtaacct cgcgctttac agatgctaac tctattattg
     3121 atgcactcgc ttcaaccatt ttatccctct ttctagacct ctctatatta gctattgtcg
     3181 gaagtgttct tttggtgcaa aatagcaggc tttttctgct atctctgatt tctatcccag
     3241 tatataccat tatcatatgt gcctttataa agccgtttga acaaatgaat catgatgtga
     3301 tgcaaagcaa tgccatgcta agctctgcta ttatcgaaga tatcaacggg atcgaaacca
     3361 taaaatcact aaccagtgaa gaaaaccgtt accaaaaaat tgacagcgac tttgtggatt
     3421 accttgataa gtcttttaag cttagtaaat ataccatctt acaagccaca cttaagcaag
     3481 gagcgcagct aattctgaat atcatcattc tttggtttgg ggctcaactg gtcattaatg
     3541 gtaaaatttc aatcgggcaa ttaattacct ttaacacact tcttgcctat tttacaaccc
     3601 ctttagaaaa tatcattaat cttcaaacca agctccaagc agctaaggtt gccaataatc
     3661 gtctcaatga ggtctatctt gtagagtccg aatttaaagc ctcgcaagcc ttatacgatt
     3721 tatcgctctt acagggtgac attcagtttg aagctgtttc ctacaggtat ggctttggca
     3781 aggatacatt atcagatatt acattaacca ttaagcaggg agcaaaagta acccttgttg
     3841 gtgtcagcgg ctcaggaaaa acaaccctag ccaagatgct cgtcaatttc tttgaacctt
     3901 ataaaggacg tataaccatc aaccaaaacg atctcaagac cattgataaa aagaatcttc
     3961 gacaatacat caactacctt ccacaacaag cctatgtgtt taatggatct atcttagaaa
     4021 atctaacctt gggagccaag caaggcatca gccaggaaga cattcttaac gcctgtgaga
     4081 ttgctgacat tcgtcacgac atcgagcaaa tgccaatggg ataccaaacc gagctctctg
     4141 atggggctgg cttatctggc ggacaaaaac agagaattgc acttgctaga gcattactaa
     4201 cccaagctcc tatactagtt cttgatgaag caaccagcgg acttgacata ctgacagaaa
     4261 agaaaatcat tgaccgtctc atgaacatga cagacaaaac gattattttc gttgcccacc
     4321 ggcttagtat cgcagagcgc actgatcaga ttgttgttct taatcaaggg caaatcattg
     4381 aaacaggcag ccaccaggaa ttaatgaaac aaggtggatt ttattaccac ctatttagtg
     4441 aataaggaga caatcatgaa tcccaatatg tttaaaagtg cggaattcta ccaaagacgc
     4501 tatcatcatt tgacaacatt cttaacaatt cccttagccc tcttgttgac ttttcttatc
     4561 cttttttctt gctttgttta taaagaaata acggtaacgt cctacggaga aatcactccc
     4621 actcaagtca ttgcaacagt ccaatctatt agcaataatc ctataattgc gaaccatctc
     4681 accaataacc agccaatcaa acaaggagac tctattattc aatatgctaa agacctagaa
     4741 gagtctcaaa agcaggtact tgagaaacaa ttagctacct acgaaaagca aaaaagcagc
     4801 cttaatactc tattgttaag cttaaaacaa ggccagaacc tttttcagaa cgatgatcaa
     4861 tttggttacg tcaatacctt taatcatttc atgagccaag cccaagatat tgaccttggt
     4921 ttctcaaaaa taaaggcaga gaccagccag caggcccagc tgattcagga ctctattgtt
     4981 gctatcaatc agcaaataaa tagtctttct caacaaatat cagactatga agagcttcga
     5041 tctgcgatca ttaaccaatc cgatagtcta tcctccaata acccacatca agccaccctt
     5101 gatgcctatc tctctcaatc tcaagcaaac caagagactg ccaccaatca gcttctattt
     5161 caaatagacc aaaatctttt aaacctaaaa acctctatag atagcctcta taggcaacgt
     5221 gctaatctac atcaatctac cagctatgat aatagcctca acacaaagct agaaatactc
     5281 cgaacacagt ttttgataac agcctctcag cagttaacag atgtcaatca tcatattact
     5341 gagctcaagg cgcaattgga gcaagccact cttcaggtaa acaatctggt gatcaaagcc
     5401 tcaaaaagtg gcattgttca gctcaatagt gcttttgaag gcaaaattag tatcccaatc
     5461 ggtcacgata ttgcctacat ttatcctagc ctcaaacaaa caaaacaagc cttgctcact
     5521 tactatgtca gctctgaatc tgtttctctc cttaagaaga accaggttgt caggctagct
     5581 ctagatagac atggaaatca accgatagtc attacgggaa ccattaaaac cattgatgag
     5641 ctagcgacca aaaccaagca gggaaatctt tttaaggtta cagccaaact aacactttct
     5701 gaaaaagaaa gcactactat tcaatatggt cagcagggac gagtgataag tgttattgcc
     5761 aaaaaaacat tctttgactt ttataaggac aagctcttta aagtgacaga ataaccattt
     5821 agcgcttttc aacgaccatt taggacatag agtacaacaa agagtcaaga taagctataa
     5881 taacatagac agtatttaaa aggagctttc aatatggata aaccaactag acaaccaaag
     5941 tttcaggaac taacgccttc tcagttaact cagattactg gaggaggctg gcttgaaggt
     6001 cttcaaaaag ttttcaatgt ctctaagcca aaactactaa aatagtaaca ttctccattt
     6061 tcaaaacacc actacctaaa ggtactgaga cactatcgga atgatgtgat cctaaacatc
     6121 aaatctgata ggtgcaagac agttttcctt tactagtggt gtttttttat aacctaagct
     6181 caagtgtttg accaaataca tgattttgac ttatagtctt aatcatcaca ttgggataac
     6241 gattgataat ttccatagca ttataaagtc ccacacctct attatccccc ttggtgctta
     6301 ctccgaaatc atatagaaag gatagatcaa tcttctcttc cttagttgta ttttcaatca
     6361 taaatagttg cttattgtcc aaagtaaagt aagaaatcgt tatcttagac gaagaagctt
     6421 caacagcagc ctctatagca ttatcacata aaatagacac aatagtaaga aaatcaatca
     6481 gctccatgcc ttgcggactg atatcctctg gaacctctaa agatactgaa atcccacttt
     6541 ctaaagcctg actaaatttt gcagctaaaa gacttttcaa ggctgtgtca gtgacatgga
     6601 taagacgccc aacatcatat ttttgcttgc gaaatcgttt atttgaatcc ttaaagaccg
     6661 attgataaac tgacctaaca atagacatgc tatcattatc tataccaaac tttaacgtgg
     6721 caatcagatt gctatagtca tgacgaaatc ctcgaacctc tctgtaaagc tcctctatct
     6781 gacgactata gctctcaata tttgccagct gcagctctct ttgaaaggtc agtctttctt
     6841 gcagtgtatc tcttagcgac cggtccagtc tcgacacagt tcccataaat ataatccaat
     6901 agccaagcat catgcattga cgataggcat aagtatcaac agctagctca tactctaaat
     6961 aagcaagcaa ttggatcaaa aaataatagc taaccataga ccagttggtc acacctaaaa
     7021 ttcttttatc cctatcagat aaaagattaa ttcttaatgc tctgaaatca tatcgtagcc
     7081 accgcaaaaa gagaaaaacc atcaaagtag atactatatc tgtaaaaatt ccccaaaatc
     7141 catcatttgt taaatgataa tcaagtttaa aaagaggtaa gataaaaaaa ccaagcagtc
     7201 ggtaccaaag gctccacagg gtaataggaa atagcccata aaatatcaat aatgtttttg
     7261 ataagggtcg cagcaatagc catgatatca ctaccatata aattggaaga ctccaataat
     7321 tgagaagtga aatgtcggca acatgattag ctatagtgaa aaaaacagca aatcctattc
     7381 ttaaaaaagt actgaaagca acttcaagcc aggttaattg acgtccactg attttggaaa
     7441 agagcactaa cgataagcct atacttgtcg tcatttctaa gaaaaataaa ataagcttca
     7501 ttaattatct cctctatgta ggttctcaat tgttgttaaa acactgttca ttttactacg
     7561 agcaattaag cagctagagc catttcgaaa ataaaccact cgctcaatct tatctaccct
     7621 aacgacattc ctatgattaa tcaaaaaaga acgatgacat tgcaaaaaac gagactcttg
     7681 cttcaaaata tccgtcaaag tccccgtaaa ttgcattctc tccttttttg tatacaaatt
     7741 gacacgatgc gctcgtgacg atgtctcaat atacaggata tcattaaaag gcacctgtac
     7801 ctgagcataa cgagatgtaa aataaaaagc actttccgct atcgtttcac tattttgccg
     7861 cacagcatat aataaagcag tctctacccg ttgaacaaac tcagtttgag gcagctcttt
     7921 atcgatatag tccaaagcag atacctgata ctgaaaagcc aagggcataa attccgagtg
     7981 agtcgttaca aaaacaatca tcgcatctgg atttatctga cgaatttgcc tagcaacctc
     8041 aagccctttt ttgttctcat tttttatctc aatatctaaa aagaatagct gctgaccaca
     8101 gttcttcttg atagcactta atagctgatg aggccttcca aaacagtcaa gtccttgaaa
     8161 taatagctgg tgcttaacct caagctcttt aatgagcttt tctaaatatc tctgctgaat
     8221 catatcatct tctaaaataa ctactctcac ctaaactcag tcccctatcc aatctgcaga
     8281 agcattagca ctactaccgt ttcaacaaaa taataagcac aataacaaaa ataaatccat
     8341 taaaaacaac tgcatcaaaa ctcataaaaa taatattttg tacttatttt agcataaaat
     8401 accatttttg aatacactaa tctctaataa actaatgcta tctagtctta gctagcaata
     8461 acctagtgct tctaacaaca ataatcagct caacaatttt tagcagctac ctttttaaaa
     8521 aaactgggat aaaaagattt ctcaggtaag aaaaatagag attcaccaaa cagtgaatct
     8581 ctattttttg aactgaaact ccttttgtcc caaactcata agatgtattg actttatgag
     8641 atgaacaatt tgttacactt gatttgatca tcggggttta gaaaaaatag tgaaaagaat
     8701 cctcataatt cgtgaaaaat ataatttctc acccaaaaat ccaattcaag attgtattta
     8761 taagaagtag catgattaaa gttatagaaa ttcttatcaa cgcttcttct tttttaacaa
     8821 caccaaatat caatagtata atcggaacta aaactaatac tactaataat attgttttat
     8881 aatccattga taatggcctg tcctgcacca acaatgcatc ctattcctgc acccaataca
     8941 tacaatggac cagagaaagc acctgtaacg attgctccac ctgcacaatg ccctgcaaca
     9001 gagccccaat taattttacc gccatttaca cttgccaaat caagctcata taacatctga
     9061 aaatcttcgt actgcttcat ggtatatact cctttcttag ttaaatctat tacctatcat
     9121 tccacccatg catgcaaaac ctcccccaat tgcaccaaca tgtgcaccaa caaatgcacc
     9181 tggaagtacg ccaatccctc ctgctggggc accccacaaa gccccacttc cagctcctat
     9241 taacatatat cctcccatgt ctttaagaca gtccttacca gaatatccac cttcaacagt
     9301 tgcaagagcc tctatattca taacatcaaa ttgattaatc gtttctgtat tcattttgaa
     9361 tacctccata acatattttt tctttatgtc gcgatcacga tttaagtata gcattctagt
     9421 atcatatttt ttctaaaagt cttaaacggt cgttttttca tcgtaaacgg tcattttcaa
     9481 tcgttttcaa ccgttcaaga caaaattaac taccattcag gattttcatt ggataaatag
     9541 ctattttttg gctctttgcc aacccactaa agctattaat aaaaaaataa gacagtagtc
     9601 acatttaggc tactgtctct tttatctaaa gccttgatcg gtaagaaaag agccagtctt
     9661 ttccaactaa tcgattattg ttgtggtttt tgtcgctttt gtagcttcac tacagcctcg
     9721 gtccttgctg tgtgtggaaa catgtcaaca gattgaatat atatcacatc atagacctga
     9781 accaagggta ccagatcacg agccaaggtt gaggtattac aggagacata aaccatttta
     9841 gctggctgat agtgtaaaat cgtttgtaat agcttgtcat ctagtcctgt tcgaggtgga
     9901 tctacaatca aggcatcagc tcggtagcct tcagcgtacc agcttgggat cagttcctct
     9961 gccttgccag tctcataata agcattgtca aagcccaatg cctgcgcatt tttcctagca
    10021 tcagcaattg cctctggaat aatatccata ccacgaacag atcttacttt gtttgcaact
    10081 gccagaccaa ttgagccaac accgcaataa gcatcaataa tatgctcctc agctgtgggc
    10141 tcaagcgcct gaaccacttg actatataaa acctctgtct gtgtgggatt aagctgataa
    10201 aaggctcttg gcgacagggc aaagctatgg ctcaaaacct cctcttgaat ggtctcctga
    10261 ccccagagaa tctcagtttt ggcgccataa atatcactcg tttttgaagt attgatgttt
    10321 aaagcaacag tcctgatttg tggaaatgca gcagtcagct cagcaataag acctgccagc
    10381 ctcacctctt tactgcttac aaaaatcaac tgaacctgat cactggcctg tgccctacga
    10441 accataactg tacgaattcc agctactctg cgttcattat agataggaat cctataccga
    10501 tcaagcagct gagtcacatg attaacaatc gcctgtgtta gctgatcctg aaccagacaa
    10561 tcatcaatgg caaccaagca atggctccct tctgaaaata agcctgcctt gacggagcca
    10621 ccaaacgaac gcgtctgaaa ctgtaatttt gctcggtaat gctgcggctc tgccattcct
    10681 aaggtatgac gaatctcaaa ctcttcatac cccttaggct taaacttttt taaggcctgc
    10741 cgaatgatgt catccttaaa gtagagctgc ttaggatagg ccagatgcat gatttgacag
    10801 cctccacagg tctcataaat ggaacaggcc ggcttcaccc ggtttttaga agccttatta
    10861 atcaccaaga gccttgcctc agcaaaattg cgcttaacag cagtcacttg acaaaaaacc
    10921 tcttctccct tcaaggctcc gggaacaaag accaaggtct ttttataaaa accaattccc
    10981 tcaccattaa tccccattcg cttaatctta agcggtattt tttgctttat tttgacattc
    11041 attcctgact aaatattact cctaatcgct taagccttgc tatcatctgc ttgccaacac
    11101 ctggaatatc aagaagctct tgagttgtcc aggccgaaaa atcctccaga gtatgaatcc
    11161 catactgatt aaacaaattg accttactta aaggaagatc aagctcctct agaaatgtta
    11221 gctcgccttc agccccttca aaaaattcct gaacataatg ctgcaggtaa tattgtgcag
    11281 tcatcaatag cggtaggata ttaaaaaagg caaggtaaat acttgataag ctgtttggct
    11341 cgtagctctc cagggcacca gcagctaaaa tatcatctat cggaaaggct ttctgtctga
    11401 caattgccac aaagtctggc accgtctcag caaggttagc caaaatatca tcagctagct
    11461 cttctctttc agctaatagc gctccaacca tcaaaggaac ctccatcaac agatctcctc
    11521 tatgataatc cttactgtca taaaaagcct ctgccatcgt aaaatcagac tttaacacat
    11581 aaagagctaa gatttcatac cttgtcccta agtgatcccc ttcatcgtat tgatgaattt
    11641 ctaagaggtg atgtaaagct ttttcataaa gaccattttg cttatacagc atcgccagct
    11701 caaatttttg agacaagtaa ggtctctctt caagattcac ccatcccata ggcttagaag
    11761 caagccaggc ctgatgctga cagtcttcat caaaggccaa atacttgatt aagtcatagg
    11821 ctctatctcc tgcaaagtgc tccaagtccg acaacaactg gttatccatg ctgtttaaaa
    11881 gagcctctaa gtcatcactg aaaaactctg tctcatgtcc aaagagcata tcatcttctg
    11941 catcagcttg gcgatagtgc tgtaagctaa caaccttatc tctatctttt ttatcttttt
    12001 ctgtcataat gccctttcaa tctattgacc atttatactc ttattttacc atttttgtta
    12061 taatgagggt atgaaaatca gtcaaattga aaagaaaaag catttatacc tcattaagct
    12121 agacaatggt gatagcctaa cggtcacaga agatacgatt gtcacattta tgctaagtaa
    12181 gcacatggtc atagacagcc aacaatggga ggacatcaaa agcttcgcac aattctcata
    12241 tggtaaaagc aaggccttag gttttattgc cttccaacaa aggagccaaa agcaagtcca
    12301 agattacctg ctaaagcatc agattagtcc tgatctcatt ccaagcatta ttgatagcct
    12361 aaaacaaggc aaatggattg atgatcagca atacgttgac acctatatac gccaaaatag
    12421 ccttactgga gacaagggac cattacttct caagcaaaag ctaatgctca agggaatagc
    12481 ctcacaactc attgagcctg tcctagcaca gactgatttt tcctctatag cacaaaaggc
    12541 tgctgaaaaa atctaccaga aatatcaaca caaattgcca agtaaggcct tgaccgataa
    12601 aatcatacaa ggacttctta acaagggctt ttcctatgac cttgccaaag gcattgtcag
    12661 tcaactaagc cttgagcagg atagtcagca catcgaagac ctgcttgatc aggaattcga
    12721 caagctatta cgaaaataca gtcgtcgcta tgatggctat cagttgaagc aaaagcttta
    12781 ccaagccctt taccgcaagg gctatgacag tgatgatatt accactaagc taaatgacta
    12841 tttctaattc taccaaggct gctgcaccga tttgacgcaa aagcttttag tcagcaacaa
    12901 agtagtccta ttatgatcct gtagctttga taatggttta gctagctcct caactgaaca
    12961 tcagatttct aaaaacttct ttaagcattt gtcagatcat attgtccaaa acagtgattt
    13021 attttctcaa ttatggtaaa ctatagagga taagtttaat tgtagaaagt tggtaaggca
    13081 tgaaattacc taaagaaggc gactttatta caattcaaag ttataagcat gatggtagat
    13141 tgcaccgaac ctggcgcgat actatggtac taaaaacaac tgaaaatgct ctgattggag
    13201 ttaatgatca cacacttgtt actgaaagcg acggcaggcg atgggtgaca cgagagcctg
    13261 cgattgttta ttttcataaa aaatactggt tcaatattat agcaatgatt cgagataatg
    13321 gtgtttccta ttattgcaac cttgcaagtc catacctgat ggacgcagaa gcgctcaagt
    13381 atattgacta tgatcttgat gtcaaagtct ttgcagatgg tgaaaagaga ttgcttgatg
    13441 tagacgaata tgaaatgcac aagcaagaaa tgcattattc acctaatctg gattttattt
    13501 taaaagagaa tgtcaagcta ttagtcgact ggatcaataa agaaaaagga ccattttcaa
    13561 aagcctatgt cagtatttgg tacaaacgtt atcttgaact gaagaatcgt tagtcgttgt
    13621 ctagcactcc accgagggtg ctttatttaa tcgctagtat agtatcacag ctgtaaactg
    13681 gactggcact tgcaatctat cagcatttgt tgtcaaattc atatcattaa ccactatagc
    13741 ttggcacaag cacagacagc ctataacacc aagtagcaat cagtatttat catcagctgc
    13801 ctagctagat caggcattca aatgacctca ttataacacc ataacaatag aaaggattga
    13861 caatggcatt tcaagcaaca aaaggacgat acgcaagctt tggcgttgca gtcagccttc
    13921 cacctgagct gattgatacc ttctgggaaa tcattgacca ttacctaaaa ggggtgtttc
    13981 ccctcaatac tgttctcacc ttcaggctaa ttaaaaataa aaaaaacctt tcttatgagt
    14041 acattgatca acaagctggg cttcggattg tttttgacta taacacacca tttaacgcct
    14101 tttaccccaa aacgctctat atcgtaaacc agcaaggaat tgaaacgatt ttattgcctc
    14161 acgagatgta ttgataagac ctcggacatc agctataaag tccttaccat tcagttgtag
    14221 ctcatcacat ctgctacaag caccaacatg agataatctt gtgtctttat cctagctctg
    14281 aatgctgtat agatattcag tcagccagat acatagcaat aaactaagct catgccggta
    14341 gaaatagtcc taacatgagc ttgacagttt tttcattctg taaatcattg ctaagcaaac
    14401 acatcaccta agccctattt cctattctgg gaaatggaaa tcttgataga acatcccaat
    14461 agtcccatca tattgagcta tatctatagg gtctgacatt ttgatatgtt atcatctcat
    14521 tttacgacaa tcactatagg ctttatgaca attggcatca ttgtcataac gattaaattc
    14581 tatatgacca aatggctagt aggaagctaa ttgctttgtg ttagcctcac ataggatctt
    14641 cacatacccc gtaatcttaa aagtagtttt aactgcacaa aacttataga acctaaaaat
    14701 caacaaacac actttaaagt acaaaaactt tgccctccct caaaaagctc tataatctct
    14761 gtagtcggta agcccactgt ggaaattata gtttttttaa ttgtacaaaa acaagcccat
    14821 atgacttatc atgaaatgca atcaaaccat cattagaaag actcatagga acaccttaag
    14881 cattactcag catttaaaaa acaatatcca accgttgact gttctaaaag ctcaccccca
    14941 catcgttatc aatcctaagc ttgattattc agttctctta tgccctcact acaaaggaaa
    15001 catgagcaaa caagacttcc aaaaagcctc taaaatccct atcttcgatt gccaaagctt
    15061 tccaacactg cttcaactca aaaaacactg ctttcagtgg aaagccagtt ctaaagtgag
    15121 ccttgctcaa actccttttg gttttaacat cacaaaaaag agcaccaatc tggtcctctt
    15181 tagacgttag
//
LOCUS       DARYMD010000048        14234 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYMD010000048 DARYMD010000000
VERSION     DARYMD010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14234
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..241
                     /locus_tag="TU818_001533"
     CDS             <1..241
                     /locus_tag="TU818_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL0924332.1"
                     /translation="DKDVNVEILREACRKTFSYRKTEFDIGKIIDLLEKLKINEAFLK
                     RWQAYSRKNLYAKDITFEEVLDNGIKMVEKIKNEN"
     gene            413..2125
                     /locus_tag="TU818_001534"
     CDS             413..2125
                     /locus_tag="TU818_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL0924333.1"
                     /translation="MQTLVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHL
                     IQMANPDAYDEKYAKWDMADLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINA
                     CDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQ
                     ARAIADWLVGMNISRLYSCLYNQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVEL
                     SMDGFILSTDRIDDKVAAEQLINLVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNK
                     YFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMITSMINNILGQNDFDTGRIKVI
                     FNSSKVTDHHAIIPTVSSMSEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVV
                     TFDGFKFTSSGKVIKDEGFTKYLKEYKTKKNEDIELPNVNIGDSLKIKDKEIKEKYTQ
                     PPKHFTENTLLKSMETAGNDALKKGIEVERKGIGTPATRAGIIENLIYKGFIQRDKKN
                     LVATHKGISLITIVADNFKSAETTAKWEMELSDISQGKSSKEEFLRRVEAEIRNELSR
                     YKKD"
     gene            2129..2680
                     /locus_tag="TU818_001535"
     CDS             2129..2680
                     /locus_tag="TU818_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL0924334.1"
                     /translation="MFDTLIKFSKDREKLDFYATDKRAIHELLKREQFLSPIYEPACG
                     MGHIGKVLEEYGYKVKATDICYRGYGEEREVDFFTVTENILDIVTNPPYFCASEFLRH
                     ALEISGPKVKIAMLFRLAFLEGQSRYELFRKYPPKRVYVFSKRLNCAKNGEFEKYKSS
                     AIAFAWFIWEVGYKGITELRWIR"
     gene            2722..3468
                     /locus_tag="TU818_001536"
     CDS             2722..3468
                     /locus_tag="TU818_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0924335.1"
                     /translation="MDKNEVLQSQENQTKEVMQEIKEEYTKTADFLEEHINQQLVIAK
                     EMKEEMQNKDFDVNIKELKALKEEITGLKAEIKRLNEMENITFGSLIIRDIKSVGNTL
                     INLQEKAVGSIKHLYDNMKHQLSYNLTKAQEKFVQMKIGIVKGLVNSMQDFIKDQQKK
                     LDSCLAKLDNLSKEIQKDEEKLEKGNLNKEKTLIKKREQSIEEKESQKEKMEKKPSVL
                     KKLKENQQKIKQEEKNKDIKALKKDKGMEL"
     gene            3485..>14234
                     /locus_tag="TU818_001537"
     CDS             3485..>14234
                     /locus_tag="TU818_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL0924336.1"
                     /translation="MNDLIKNYENIPDEMKKEKRWCLYKIIQRDGKNTKLPLMPNKEP
                     AKSNDKATWNSYEDCIMALKHNVGEGLGFFLGDGYIGIDIDKVSDDIMEYNTNHHVSS
                     MTADFLREVSTYAEISPSKTGLHFIGKGEVPGERKRYKNLEIYDKDRFFTVTGNVIKD
                     RDRSKIESIDSELKPLYEKYMPKTNKISAENKRSPTVTSYNGDQDILEKLFDRGYFSY
                     AGEDLRQIYYGNYERYFNSQSEADFFMLQRLLYYTGNVEMAISFMESSGLKREKWYKR
                     RGNTDYIHYIADKAISSINQFYDWEKVYTSKEKIEEKRYENKKKKEGDTVPRYEFDEV
                     KQILDFAKEEFKENIDRYETYLKVMGNNYKYPYFNQLSIYTVNENATACAEYDYWKSI
                     GRNVNRGEKGIPVLDIEREKIKYIFDASQTVSLNHNISEVKLWEYSNNKHVAALDTLI
                     DVFKEKNSNLIFSTEDKINTIVSLYTKQLLNKVLNSLSDETLKENKKVQILHFLEESA
                     KVSVYERMGVAFSGDIEKLEMLSNVSSMQDIDRLLFFTSNNVKRILMDISREISKVEE
                     REKISEIQKREQTNSIAERYTNVTDEINGNTEIIENEKERNEGGLEDERNRSIGEEGV
                     HPRKRDLYTDRKRESIRETGRDLQIGENGGWSGSISSEYENAGENKRKQTEPIWQGET
                     EISQRGETRGISDYADGRNFNGSFDRYSGTSGGFPEYRRAEDERSLENDHRNAGSGLS
                     EIHRTEEELGYDTNKNGYGTDHLGIDEYRKENIQKIEQNHVENEEKEVERTSFSFAQN
                     VGVQGRFELPMQQEEIGAVLIHGGNEDNLHLKVLAEYSKEKSMEELADFLQKTFQGGN
                     GYELNGNKVCAWYEMDGIHLSNDVSSRENPMQILPWKDAAIRIGELIDYGKYSTNVEV
                     AEAFSFERAELSEKLWFLKGDLSDEVKNQFLPILNEKQRNGYPEKTEYLTKKLEDKEF
                     RVNLKEEYIEFFKAYKENSNVLRFHNHDLDDISKRLDDLELPRKEFTSTLIELPAIQG
                     FITEDEIDRYLSSGSNVSGGKERIYNFFREARTTEERANFLKDEYGTGGQTHALSRAR
                     GSSEWHDAKGIKLEKENCKDIILKWNQVVKKIDNLIENGKYIQEDVYTEQESIKTEEE
                     YFDEDTYTEQNSKENEQDWQREQEILLIQDEREVSYEEAEEIYERQAEIEHNAFATGV
                     ENNISSTQSNKDYWIVEFNEGSNLIEKNYAGEVVTKKLLDEIKVLDEKIRVHNKTVGE
                     DEYGEMTDEWVGYSKFYFDHIVDGKVEEHFRMDIGDGNEVNQRDFQYLYEQIEPEKEN
                     KEYGMDSIDSVIKDILEKESMTVVSSKDDYIKLFPYFRNFVYTDGLRLDEYNPFEDDE
                     NISDLIRLTFFQNNDGEYRVVYNNADSLLYSSNVDYFLEKIEAEKVRLEDNIAEIPNE
                     DKIAVKVGNYYAVVEKERVKDISLEETGVRVYPKENNFEGKIYPLYRGSTFEESAKID
                     KLFDEIAIGMKEVNLTDLNDVFYLENQGLYEISSDRVTEEKAGYDFEVASFNEQFPDY
                     YNDIYVYNRNLKIDGANQNIAYINRENEIHFNVNLPEEEKAKVLEIRDKKEVLSTLIF
                     KDVKEVGEYQFHPQSEEFILNELSISEEKLKAPEHITDKIDKKEGYEAELVLDMKNKE
                     LRQHLRYNGYMLSSNVAVSYDSYKAILKNLSYLLDDNHRNIMLTGYVNEQIEKDKAKE
                     ERKEPVYQEGMNVRYQGKEYIISEIQDYKTYKTIKLDDSEGYLNGFITGSEIIPFRNE
                     RELDLEIISTTEKLQEQSINGEDLILLDIEEYNKKGLSVIFQNKEYEITGNNFNPVGM
                     SRLQLVSNTEKLMTEISYTPQRPVANLYAKKDLLERFNLNEKNSEKSIEAKQMSLTDI
                     FEEQDTTKGKEEISSEKERVPVNIGAKVIYQGEEYTVSAFEYNNILEKNDIWLNPVSK
                     NNHQIPIVSFSDREELNEKLIVIDTNLNLGEDKSELLHHSLDVINDKGSVIANQFIVK
                     VDNQNRELTVYSEQNPNSHREFELSFDYLNGLGQIDGDGNNLKLTKHKKETIDKKLKS
                     YHSWKEDGEKRGIPGIAGSSITSPITDEMFWQMKEYEEKLKEEERYAPDDKYLGGIPP
                     INYKITKEDEILPPSERLKNNIEAIKVLKEIEERHSHATKEEQDILSRYVGWGGLSDV
                     FDEEKGGQWKDAREFLKENLSPSEYDAARESTLTAFYTPKIVIDSIYQAVLNMGFESG
                     NILEPSMGTGRFIGNLPDSMKGSKFYGVELDSISGRIASRLYPNAKIQIKGFEETTFS
                     NNLFDVAVGNVPFGEYKIVDREYEKNNFLIHDFFFAKTLDKVRSGGVVAFISSSGTMD
                     KKSEDIRRYISERAEFLGAIRLPNNTFKGEAGTEVTSDIIFLKKRDRLVKLDEEWVKL
                     GTDERGLTYNKYFVDNPDMVLGNMEEISSRFGTSLACVADENSTLKEQLDTAIKNIKG
                     SYEKIELNNEFEVETIPADDSVKNYSYAVIDDKVYFRENSVMQKLNLNKNDEEKVRAY
                     LGIEKALRQVIAYQKEDYSDTEIKEKQGELNRIYDEFSKKYGILNSKANKKLFREDAN
                     YSLLSTLEKLDKEGNFIEKSDIFTKRTIKKAVAIEHTDNLTEALILSISQKGKVNFEY
                     MEKLTEKTRGEIIEGLKGEIFLNLDGFDPSDTTPFSSAIDLGDFSRSYVTADEYLSGN
                     IRDKIEVIDSYIKNVEHEFEQNEQLENIDADVLKQGSETLKKELSSLNYQRQKLLEVM
                     PKELEASEITVRMGATWIPEKDYKSFMFHLLKTSASNRWNIDIKYTNFTGEYRVEGKS
                     IDKGNDLANFTYGTSRVSAYKLIEDTLNLRDTNVYDQVIDENGKKSSVLNQKETMLAR
                     SKQEIIKEEFKNWIFDDIDRRTRLVKEYNEKFNSIRLREYDGSNLTFDGMNPEIELRP
                     HQRDAIARGLFGGNTLLAHEVGAGKTFEMIGIAMESKRLGMSNKSMFVVPNHIVEQFG
                     REFNELYPAANILCATEKDFTPDKRKRFCSRIATGDYDAVIIGHSQFEKIPISKQRQE
                     YELQSQIDEIIDFIEEYKRNRDQKFTVKQLEKTKKGLEAKLKKLNDDYRKDDVVTFEE
                     LGIDKLFVDEVHAFKNLYVFTKMRNVAGITTTDSQKSSDMLMKCRYMDEITGNKGIVF
                     ATGTPVSNSMAELYTMQRYLQYDELKKMHLQHFDSWASTFGETVTAIELNPEGNGYRS
                     KTRFAKFYNLPELMNMVKQFMDIKTADVLNLPVPNAHYETIKTKPTEEQKQILETFSE
                     RADKVRGKQVDSSVDNMLLITNDGKKMALDQRLINPLLPDDPNSKVNTCVNNIFSIWD
                     KYRDEKSTQLVFCDMSTPSSEFNIYDDIKEKLTKMGIPKNETEFIHNAKNNKEKDKIF
                     DKVRKGEIRVLLGSTQKMGAGTNAQNKLIATHDLDVPWRPADLEQRKGRIVRQGNEND
                     DVHIFRYITENTFDAYLFQTLETKQTYISQIMNSKTPVRVAEDIDEATLNYAEIKALA
                     TGNPLIREKMDLDVEVSKLKMLESNFKSNLYKMEDKVVKVYPKEIKSLKEKIENLKKD
                     I"
BASE COUNT         5754 a         1732 c         2977 g         3771 t
ORIGIN      
        1 ggataaagat gtaaatgtag agatattaag agaggcttgc agaaaaactt ttagttatag
       61 aaaaacagaa tttgacatag gtaaaatcat agacttactg gaaaaattga aaataaatga
      121 agcctttttg aaaagatggc aagcttattc aagaaaaaat ctgtatgcga aagatataac
      181 ttttgaagaa gtattggaca acggaataaa aatggtggaa aaaataaaga atgaaaatta
      241 gcatataacg gttttacaat gaaaagaagg cgtcaaacat ttttttgtaa gttagttccc
      301 aaacaggaaa atggattaaa aaatagaaaa tgaaatatat aaaactttaa aagacaattg
      361 gagaaatgca aactctgatt gtcttttttc atgtagaaaa aaggaggaat ttatgcaaac
      421 actggtgata agtgaaaaac cgagtgttgc aataagcata tcaaaggtgc ttggagcaac
      481 aaaaaagaaa gacggatata atgagggaaa tggatatagg gtaagttggt gtgttggtca
      541 tttaattcag atggcaaatc cggatgctta tgatgaaaag tatgccaagt gggatatggc
      601 tgatttaccg attattccca aggactataa gtatgaagta gcaaaggcaa ccaagaagca
      661 attcaacatc cttaaaaagc tgatgaatga taaagaaatt gatacggtta taaatgcttg
      721 cgatgcaggt cgtgagggag agagcatttt tagacttgtt tataatcaag tgaattgtaa
      781 aaagaaaatg aaacgccttt ggatttcatc tatggaagat agtgcgatta aagagggttt
      841 tgatcatcta aaagacggaa agaaatatga caatctcttt gaatcggcac aggcaagagc
      901 cattgcagat tggttagtcg gaatgaatat tagtagactt tattcctgct tatataatca
      961 aaattactct gtcggtaggg tgcagacgcc aactcttgcc atgattgtaa aacgagatga
     1021 cgagatagca aactttaaaa aagaaaaata ttatactgta gagctatcta tggacggttt
     1081 tatactttcc acagacagaa ttgatgataa ggtagcagca gagcagctaa tcaatttagt
     1141 tggtgataag attgaaatta ccgatgtcat tcaaaatgaa aagattacaa agccggattt
     1201 accttttgac ctgacaacac ttcaaagaga gtgcaataaa tattttggat actcagctaa
     1261 gcagactctt gattatgctc aaagtctgta tgagaagaaa cttattacct atccaagaac
     1321 agacagtaga tgccttactg aagatatgat tacaagtatg ataaataaca tattgggaca
     1381 aaatgacttt gatacagggc gtattaaggt catttttaat tcaagcaagg taacggatca
     1441 tcatgctatt ataccgacag taagttcaat gagtgaagat ttattgagta ttccggagag
     1501 tgaagcaaaa gtgtatggac ttatttttaa taagttacac gcaagtgtgg gctatccttt
     1561 aatcgagaat acaacaaaga ttgtagtgac ttttgacggc tttaaattta caagttccgg
     1621 aaaagtaatt aaggatgagg ggtttactaa gtatttaaag gaatataaga cgaaaaagaa
     1681 tgaagatata gaacttccaa atgtaaatat aggtgatagt cttaaaatca aggataaaga
     1741 aatcaaagaa aaatatacgc aacctccaaa acattttacg gaaaacacct tattaaaaag
     1801 catggaaaca gcaggaaatg acgctttaaa aaaaggtatt gaggttgaaa gaaagggtat
     1861 tggcacaccc gcaactcgtg cagggattat agaaaatcta atttacaaag gctttattca
     1921 aagagataag aaaaatcttg tagctacaca taaaggaatt agtcttataa caattgttgc
     1981 agacaacttt aaatctgctg aaacaactgc aaagtgggaa atggagttgt ctgatatttc
     2041 tcaagggaaa tcttcaaagg aagaattttt aagaagagta gaagctgaga taagaaatga
     2101 attatcccgt tataaaaagg attagtctat gtttgatact ctaataaaat ttagtaaaga
     2161 cagagaaaaa ttggattttt atgccacaga taaaagggca attcatgaac ttttaaaaag
     2221 agagcagttt ctatctccta tttatgagcc ggcttgtgga atggggcata tcggaaaagt
     2281 tctggaagaa tacggttata aggtaaaagc tacagatatt tgttataggg gatatggaga
     2341 agaaagagaa gttgattttt ttacagtaac agaaaatata ttggatatag taaccaatcc
     2401 accatatttt tgtgcaagtg agtttttaag gcacgctctt gaaatatcag gacctaaagt
     2461 aaagatagca atgctatttc ggttggcttt tttggaaggt caatcaagat atgaattatt
     2521 taggaaatat cctccaaaga gagtatatgt attttccaaa aggcttaatt gtgcaaaaaa
     2581 cggagaattt gagaaataca aaagcagtgc tattgccttt gcctggttta tatgggaggt
     2641 gggatacaaa ggtattacgg agttaaggtg gattagataa aaggatggaa taaaacaact
     2701 gaaaaaacga aggaggatag tatggataag aatgaagtat tacaatcaca ggaaaatcag
     2761 acaaaggaag ttatgcagga gattaaagag gaatatacca aaacagctga ctttttagaa
     2821 gaacatataa atcagcagct tgtgattgct aaggaaatga aagaagagat gcaaaataag
     2881 gactttgatg taaatatcaa agaattgaaa gcactcaaag aagaaatcac cggattaaaa
     2941 gctgaaatta aacgattaaa cgaaatggaa aatataactt ttggttcatt gattataaga
     3001 gatatcaaat ctgtaggaaa tacccttatc aatttacagg aaaaagcggt aggaagtatt
     3061 aaacatctgt atgataatat gaaacatcag ctttcctata accttaccaa agcacaggaa
     3121 aaatttgtac agatgaaaat aggaattgta aaaggattgg taaattccat gcaggatttt
     3181 atcaaggatc aacaaaagaa actggatagt tgcttagcaa aacttgataa tctatctaaa
     3241 gaaattcaaa aagatgaaga aaaactggaa aaaggcaatc tgaataaaga gaaaaccctg
     3301 ataaaaaaaa gggaacaaag catagaggaa aaagaaagtc aaaaggaaaa gatggagaaa
     3361 aaaccgtctg tgctaaaaaa attaaaggaa aatcagcaaa aaatcaagca ggaagaaaag
     3421 aataaagata taaaggcact taaaaaagat aagggaatgg aactataaaa aagaggtggt
     3481 agttatgaat gacctcataa aaaactatga aaatattcct gatgagatga aaaaagagaa
     3541 gcgttggtgc ctatataaaa tcattcaaag agacgggaag aacacgaaac ttccactaat
     3601 gccaaataaa gagccggcaa aatcaaatga taaagctaca tggaatagct atgaggattg
     3661 tatcatggca ttaaaacata atgttggcga agggcttggc tttttcttag gagatggata
     3721 cattggaata gatattgata aagtaagtga tgacattatg gagtacaata cgaatcatca
     3781 tgtaagctct atgacggctg attttttaag agaagtttcc acctatgctg agatttctcc
     3841 atcgaaaaca ggactacatt ttattggaaa aggagaggtg ccgggagaaa gaaaaagata
     3901 taaaaatctt gaaatttatg ataaggatag gttttttaca gttaccggta atgttataaa
     3961 ggatagagat aggagcaaaa tagaaagtat tgacagtgag ctaaagccct tatatgaaaa
     4021 atatatgcca aagacaaata aaattagtgc tgaaaataaa agaagtccaa cggttacttc
     4081 ttacaatggg gatcaggaca tattagaaaa gttatttgac aggggatatt tttcatatgc
     4141 aggagaagat ttaagacaaa tttactatgg taattatgaa cgctatttta acagccaatc
     4201 ggaggctgat ttttttatgc tacaaaggct gctttactat acaggaaatg tagaaatggc
     4261 aatatcattt atggaaagta gcggactgaa aagagaaaaa tggtataaaa gacgaggcaa
     4321 taccgattat atccactata ttgcagataa ggcgataagc tctatcaatc aattttatga
     4381 ttgggaaaaa gtatatacat caaaggaaaa aatagaagaa aaaagatatg aaaataagaa
     4441 gaaaaaggag ggagatacag tgccaagata tgaatttgat gaagtcaaac agattcttga
     4501 ttttgcaaaa gaagaattta aagaaaatat agacaggtat gaaacttatc tcaaagtgat
     4561 gggaaataac tataaatatc cgtactttaa ccagcttagc atatatacgg taaatgaaaa
     4621 tgcaactgct tgtgcagaat atgactattg gaaaagtata ggaagaaatg taaatagagg
     4681 agaaaaagga atacctgttt tagacattga aagagagaag ataaagtata tctttgatgc
     4741 aagtcagaca gtaagtttaa atcacaacat ttctgaagta aagttatggg aatatagcaa
     4801 taataagcat gtagctgcct tagatactct tatcgatgtt ttcaaagaaa aaaacagtaa
     4861 ccttatattt tctactgaag ataagataaa tacaatcgtt tcactatata caaagcaatt
     4921 actaaataag gtacttaatt ctttaagtga tgaaacttta aaggaaaata agaaagtaca
     4981 aattcttcat tttttggaag aatctgcaaa agtatcggta tatgagagaa tgggagttgc
     5041 attttccggt gatatagaaa aattagagat gctttcaaat gtttcaagta tgcaggatat
     5101 tgacagatta cttttcttta cttcaaacaa tgtaaaaaga atacttatgg atataagtag
     5161 agaaatttca aaagtggaag aaagagaaaa aatttcagaa attcaaaaaa gggagcagac
     5221 aaatagtatt gcggagcgtt atactaatgt tacagatgaa attaacggaa ataccgaaat
     5281 tatagaaaat gaaaaagaaa gaaatgaagg aggtttggaa gatgaaagaa accgtagtat
     5341 tggcgaagaa ggagtacatc ctagaaaacg agatttatac accgatcgta aaagagagtc
     5401 cattcgagag acagggaggg acttacagat tggagaaaat ggaggatgga gcggaagtat
     5461 tagttccgaa tatgaaaatg ccggagaaaa taaacgcaag caaactgaac cgatttggca
     5521 aggagagact gaaatatctc aaagaggaga aacaagagga atatcagatt atgctgatgg
     5581 aagaaacttt aatggatcat ttgatagata ttcaggaaca agtggaggat ttcctgaata
     5641 tagaagagcc gaggatgaaa gaagcttgga aaatgaccac agaaatgcag gatcaggact
     5701 ttctgaaata cacaggactg aagaagaact tggatatgac actaacaaaa atggctatgg
     5761 aacagatcat ttgggtatag atgagtatcg taaagaaaat atacagaaga tagaacaaaa
     5821 tcatgtagaa aatgaggaaa aagaagtcga gaggacttct ttttcttttg ctcaaaatgt
     5881 aggagttcaa ggaagatttg aattaccaat gcagcaagaa gagattggtg ctgttttaat
     5941 tcatggagga aatgaggata atttacattt aaaggtttta gccgaatatt ctaaagaaaa
     6001 aagcatggaa gaattagctg attttcttca aaaaactttt caaggaggaa atggatatga
     6061 actaaatgga aataaggttt gtgcttggta tgaaatggac gggatacatt tatccaatga
     6121 tgtttcctca agagaaaatc ctatgcagat tttaccatgg aaagatgcag caatacgcat
     6181 aggagaattg attgattatg gaaaatacag tacaaatgtg gaggtagcag aagccttttc
     6241 ttttgaaaga gcagaacttt ctgaaaagct gtggttttta aaaggagatc taagtgatga
     6301 ggtaaaaaat cagtttttgc caattctaaa tgaaaaacaa agaaacggat atcctgaaaa
     6361 aacagagtat cttacaaaaa aattggaaga taaagagttt agagtgaact taaaagagga
     6421 gtatatagag ttttttaagg cgtataagga gaactcgaat gttttaagat ttcataatca
     6481 tgatttagat gatatatcaa aacgattaga tgatttggaa ctgccaagaa aagaatttac
     6541 ctcaacactt atagaattac cagcaataca gggatttatc acagaagatg aaattgatag
     6601 atatttaagc agcggtagca atgtatccgg cggaaaagaa agaatatata acttttttag
     6661 ggaagcccgt actaccgaag aacgagcaaa ttttttaaaa gacgagtacg gaacaggagg
     6721 acagactcat gctttatcaa gggcaagagg aagtagtgag tggcacgatg ctaaggggat
     6781 aaaacttgaa aaagaaaatt gtaaggatat tattttgaaa tggaatcagg ttgtaaaaaa
     6841 aatagataac cttattgaaa atggaaaata tattcaagaa gatgtatata cagagcaaga
     6901 aagcataaaa actgaggaag aatattttga tgaagatacc tatacggaac aaaactctaa
     6961 agaaaatgaa caagattggc aaagagaaca ggaaattttg ctgattcaag atgaaagaga
     7021 agtatcttat gaagaggcgg aggaaatata tgaaaggcaa gcagaaatag aacataatgc
     7081 ctttgcaacc ggtgtagaga ataacatatc gtcaactcaa agtaacaagg attattggat
     7141 tgtagaattt aatgaaggct caaatctgat agaaaaaaat tatgccggag aagttgttac
     7201 gaaaaaattg cttgatgaaa tcaaggtgct tgacgaaaaa attagagttc ataataagac
     7261 tgtcggtgaa gatgaatacg gagaaatgac agatgaatgg gtaggttatt ctaaattcta
     7321 ttttgaccat attgtagacg ggaaagtaga agaacacttc agaatggata tcggggatgg
     7381 aaatgaggta aaccaaagag attttcaata tctttatgag cagattgaac cggaaaaaga
     7441 aaataaagaa tacgggatgg atagtataga tagtgtcata aaagatattt tagaaaaaga
     7501 atctatgact gtggtatcaa gcaaagatga ttatataaag ttatttccat attttagaaa
     7561 ctttgtatat accgatggtc taaggcttga tgaatataat ccgtttgaag atgatgaaaa
     7621 tatttcggat ttaattcgac tgactttttt ccaaaataat gatggagaat atagggtagt
     7681 ctataacaat gcggacagtt tactgtattc aagcaatgtt gactattttt tggagaaaat
     7741 agaggctgaa aaggtaaggt tagaagataa tatagctgag ataccgaatg aagataaaat
     7801 tgccgttaag gttgggaatt actatgctgt tgtagaaaaa gaaagagtaa aggatatatc
     7861 cttagaagaa acaggagttc gtgtttatcc gaaagaaaat aactttgagg gaaaaattta
     7921 cccattgtat cgtggcagca cctttgaaga aagtgcaaaa atagataaac ttttcgatga
     7981 gattgcaata ggcatgaaag aggtcaattt gaccgattta aatgatgttt tttatcttga
     8041 aaatcaagga ctttatgaaa tttcatcgga tagggtaacg gaagaaaaag ccggatacga
     8101 ttttgaagtg gcaagtttta atgaacagtt tcctgattac tataatgaca tttatgtata
     8161 taacagaaat ttaaaaatag atggtgctaa tcaaaacatt gcatatatca atagagaaaa
     8221 tgaaatacat tttaatgtaa atctaccgga agaagaaaaa gcaaaggtgc ttgaaattag
     8281 agataagaaa gaagtcttat caactcttat ttttaaagat gtaaaggagg tcggcgaata
     8341 tcagtttcat ccacaaagcg aagaatttat cttaaatgaa ttgagtatat ctgaagaaaa
     8401 attaaaagca ccggaacata taacagataa gattgataag aaagaaggct atgaggctga
     8461 acttgttttg gatatgaaaa acaaggagtt aaggcagcat ttaagatata acggatatat
     8521 gttaagtagc aatgtggcgg tttcctatga tagttataaa gcaatactta aaaatctttc
     8581 ttatctgctt gatgataatc atagaaatat tatgcttacc ggctatgtca acgaacagat
     8641 tgaaaaggat aaagcaaagg aagaaagaaa agaacctgta tatcaagagg gaatgaatgt
     8701 aaggtatcaa ggcaaagaat atatcatttc agaaattcaa gactataaaa catataaaac
     8761 aataaagcta gatgattcag aaggatattt aaacggcttt ataacgggca gtgaaattat
     8821 tccttttaga aatgaaagag aacttgattt ggaaatcata tctacaacag agaagttaca
     8881 agaacaaagt ataaatggtg aagatcttat tctgttagat attgaagaat ataacaaaaa
     8941 aggactttcc gttatctttc aaaataaaga gtatgaaatt acaggaaata attttaatcc
     9001 tgtaggaatg agcaggttac aacttgtctc gaatacagaa aaactgatga cagaaatttc
     9061 atatacacct caaagaccgg tcgcaaatct ttatgcaaaa aaagatctcc ttgaaaggtt
     9121 taatttaaat gagaaaaata gtgaaaaaag tattgaagca aagcaaatgt ctttaacaga
     9181 tatatttgag gaacaggata caacaaaggg aaaagaagaa atttcaagtg agaaagaacg
     9241 tgtacctgtc aatatagggg caaaggtaat ctatcaggga gaagaatata cagtaagtgc
     9301 ctttgagtat aataatattt tagagaaaaa tgatatatgg ctaaatcctg tatcaaaaaa
     9361 taatcatcaa attccgattg taagtttttc tgacagagaa gagctaaatg aaaagctcat
     9421 tgttatagat accaatctta acttaggaga agacaagtcg gaactgttac atcatagttt
     9481 agatgtaata aatgataaag gttctgtgat tgccaatcag tttattgtaa aagtcgataa
     9541 tcaaaacagg gaacttacag tatatagtga acaaaatcct aatagtcata gagaatttga
     9601 actttctttt gattatctaa acgggcttgg gcaaattgac ggagatggaa ataatctaaa
     9661 acttacaaag cataaaaaag aaaccattga taaaaaattg aaaagttatc attcttggaa
     9721 agaagatggg gaaaaaagag gaattccggg aatagcaggt tcttctatta cttcacctat
     9781 tactgatgaa atgttttggc agatgaaaga atatgaagaa aaattaaaag aggaggaaag
     9841 atacgcccct gatgataagt atttgggagg tattcctcca atcaattaca aaatcacaaa
     9901 agaagatgaa atcttgccgc cgtccgaaag gcttaaaaat aacatagaag ccatcaaggt
     9961 attaaaagaa attgaggaaa gacatagtca tgcaacaaag gaagaacagg atattttgag
    10021 tagatatgtc ggctggggtg gactttctga tgtctttgat gaagaaaagg gaggacaatg
    10081 gaaagatgca agagaattct taaaagaaaa tctatcaccg tctgagtacg atgcagcaag
    10141 ggaaagtacc cttacagcct tttatacacc gaagattgta atagacagta tctatcaagc
    10201 cgtattaaat atgggatttg aaagtgggaa tatcttggaa ccaagtatgg gaactggcag
    10261 atttataggc aatcttccag acagcatgaa aggcagtaaa ttttatggtg tagaacttga
    10321 cagtataagt ggtaggatag caagtaggct atatcctaat gctaaaatac agatcaaagg
    10381 ttttgaagaa acgacttttt caaataatct gtttgatgta gcggtgggaa atgtaccgtt
    10441 tggagaatat aagatagttg atcgtgagta tgagaaaaac aattttctta ttcacgattt
    10501 tttctttgcc aaaaccttgg ataaagtacg ttccggtgga gtagtagcct ttataagttc
    10561 aagtggaact atggataaaa agagtgaaga tatcagaaga tatatttcag aaagagcaga
    10621 gtttttagga gcaattagac tacctaataa tacttttaaa ggcgaggcgg gtacggaagt
    10681 aacaagtgat attatttttc ttaaaaagag agatcgactg gtaaaacttg atgaagaatg
    10741 ggtaaaactt ggcactgacg aaagaggact gacatataac aaatactttg tagataaccc
    10801 tgatatggta cttggaaata tggaagaaat atcaagcaga tttggaacaa gtcttgcctg
    10861 tgttgcagat gaaaatagta ctctgaaaga acagctggat accgccatta aaaacattaa
    10921 aggaagttat gagaagatag aattaaataa tgaatttgaa gtggaaacca ttccggctga
    10981 tgacagtgtg aaaaattatt cttatgcagt aattgatgat aaggtatatt ttagagaaaa
    11041 ttccgttatg caaaaattga atttaaataa aaatgatgag gaaaaagtaa gggcatatct
    11101 tggaatagaa aaagcattaa gacaggtaat tgcttatcaa aaagaagatt attccgatac
    11161 ggaaattaag gagaagcaag gggagttaaa tcgtatttat gatgagtttt ccaagaaata
    11221 cggaatttta aacagtaagg cgaataaaaa actgtttcgt gaagacgcta attattcttt
    11281 actgtccact ttggaaaagc tggataaaga aggaaacttt atagaaaaat ccgatatctt
    11341 tacaaaaaga acaataaaaa aagcagtagc catagagcat accgacaatc tgacagaagc
    11401 acttatccta tctatttctc aaaaagggaa agtcaatttc gagtatatgg aaaagctcac
    11461 tgaaaaaaca agaggagaaa tcattgaagg attaaaggga gaaatattct taaatttaga
    11521 tggatttgat ccaagtgata cgactccttt ttcttcagcc atagacttgg gagatttttc
    11581 aagatcttac gtaactgctg atgaatattt atctggaaat atcagagata aaatagaagt
    11641 aatagattcg tatataaaga atgtagaaca tgaatttgaa caaaatgaac agcttgaaaa
    11701 tattgatgca gatgtactga aacagggtag tgagacttta aaaaaagaac tgtccagttt
    11761 aaattaccaa agacaaaagc tgctagaagt aatgccaaag gagcttgagg caagtgaaat
    11821 aaccgttaga atgggagcaa cttggatacc tgagaaagat tataagagct ttatgttcca
    11881 tcttctaaaa acatcggcat ctaatagatg gaatattgat attaaatata ccaattttac
    11941 aggggagtac agagttgaag gtaaaagtat agataaagga aacgaccttg ccaatttcac
    12001 atacggaaca agcagagtaa gtgcatataa actgattgaa gatacattaa accttagaga
    12061 taccaatgta tatgatcaag tcattgatga aaacggaaag aaaagttctg tactaaatca
    12121 aaaagaaacg atgcttgcaa gaagtaaaca ggaaattatc aaagaagagt ttaaaaattg
    12181 gattttcgat gatatagaca gaagaacaag gcttgtaaaa gaatacaatg agaaattcaa
    12241 ttcgataagg cttagagaat atgatggaag taatttaact tttgacggaa tgaatcctga
    12301 aatagagctt agacctcatc aaagagatgc gattgctaga ggacttttcg gtggaaacac
    12361 cctacttgca catgaagttg gagctggaaa gacttttgag atgataggaa ttgctatgga
    12421 gtctaaaagg cttggaatga gtaacaagtc aatgtttgta gttccaaacc atattgtaga
    12481 acagtttggt agagagttta atgaactgta tccggcagca aatattcttt gtgcaacaga
    12541 aaaagacttt acaccagata aaagaaaaag attttgctca aggattgcaa ccggtgatta
    12601 tgatgcggta attatagggc attcgcagtt tgaaaagatt ccaatttcaa agcagcgaca
    12661 ggagtatgaa cttcaaagtc agattgatga aattatagat tttatcgaag aatataaaag
    12721 gaatagagat cagaaattca ccgttaagca gcttgaaaaa acgaaaaaag gactggaggc
    12781 aaaactaaag aaattaaatg atgattatag aaaagatgat gtcgtaacct ttgaagaatt
    12841 ggggatagac aagctatttg tagacgaagt tcatgctttt aaaaatttgt acgtttttac
    12901 aaaaatgcgt aatgtagcag gaattacaac cacagattct caaaaatcaa gtgatatgct
    12961 gatgaagtgc agatatatgg atgaaattac cggtaataag ggtattgtat ttgcgacagg
    13021 aacccctgtg agcaattcta tggcagagct ttataccatg cagcgttatc tccaatatga
    13081 cgaacttaaa aaaatgcact tgcaacactt tgattcttgg gcatctactt ttggagaaac
    13141 tgttacagca attgaactta atcctgaagg gaacggatat cgaagcaaga caagatttgc
    13201 aaaattttat aaccttccgg aactgatgaa tatggtcaag cagtttatgg atataaagac
    13261 tgctgatgta ttaaatcttc ccgttccaaa tgctcattat gaaacgataa aaaccaaacc
    13321 gacagaagaa caaaaacaaa tccttgaaac tttttctgag agagctgata aggttagagg
    13381 aaaacaggtg gattcctctg tcgataatat gcttctgatt actaatgacg gaaagaaaat
    13441 ggcacttgac caaaggttaa ttaatccatt acttcctgat gatccgaaca gtaaagtaaa
    13501 tacctgtgta aataatatat tcagtatttg ggataaatat agggatgaga agtccacaca
    13561 attagttttt tgtgatatgt caacaccatc aagtgaattt aatatttatg atgatataaa
    13621 ggagaagctg acaaaaatgg ggattcctaa aaatgaaaca gagtttattc ataacgcaaa
    13681 gaacaacaaa gaaaaagata agattttcga taaggtacga aagggtgaaa ttcgtgtgct
    13741 tctcggttca acgcagaaaa tgggagcagg gacaaatgct caaaataaat tgattgctac
    13801 ccatgatctc gatgtaccct ggaggcctgc ggatttggag cagagaaaag gaagaattgt
    13861 aaggcaaggt aatgaaaatg atgatgttca tatctttcgt tatattacgg aaaatacctt
    13921 tgatgcgtat cttttccaaa cacttgaaac caagcaaact tatatatctc aaataatgaa
    13981 ttcaaagaca cctgtaagag tagcggagga tattgatgaa gctacattaa attatgcgga
    14041 gattaaagca cttgcaacag gaaatccgct tattcgtgaa aaaatggacc ttgatgttga
    14101 ggtaagtaaa cttaaaatgc tggagtccaa ttttaaatcc aacctatata aaatggaaga
    14161 taaggttgta aaagtatatc caaaagaaat taaaagtcta aaagaaaaaa tagaaaattt
    14221 gaaaaaggat atag
//
LOCUS       DARYMD010000049        14029 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYMD010000049 DARYMD010000000
VERSION     DARYMD010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14029
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..165
                     /locus_tag="TU818_001538"
     CDS             <1..165
                     /locus_tag="TU818_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924337.1"
                     /translation="VTYDSLVGQTRRHFDDKVAQARGLATKFKTVKEQLEEGIERTIA
                     TDQKLGGDFS"
     gene            162..554
                     /locus_tag="TU818_001539"
     CDS             162..554
                     /locus_tag="TU818_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924338.1"
                     /translation="MTALEKIRAAIRQKEEELEELQEHYHQERLQMAAAHDELRGNYN
                     QLQELYASTYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            573..857
                     /locus_tag="TU818_001540"
     CDS             573..857
                     /locus_tag="TU818_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924339.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGCLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     gene            complement(1056..1304)
                     /locus_tag="TU818_001541"
     CDS             complement(1056..1304)
                     /locus_tag="TU818_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL0924340.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLS"
     gene            complement(1358..2278)
                     /locus_tag="TU818_001542"
     CDS             complement(1358..2278)
                     /locus_tag="TU818_001542"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL0924341.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQVYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
     gene            2512..3141
                     /locus_tag="TU818_001543"
     CDS             2512..3141
                     /locus_tag="TU818_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0924342.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            3240..4517
                     /locus_tag="TU818_001544"
     CDS             3240..4517
                     /locus_tag="TU818_001544"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL0924343.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKMLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            4531..5193
                     /gene="deoC"
                     /locus_tag="TU818_001545"
     CDS             4531..5193
                     /gene="deoC"
                     /locus_tag="TU818_001545"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL0924344.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            5180..5569
                     /locus_tag="TU818_001546"
     CDS             5180..5569
                     /locus_tag="TU818_001546"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL0924345.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGNNIE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            5660..6712
                     /locus_tag="TU818_001547"
     CDS             5660..6712
                     /locus_tag="TU818_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL0924346.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAVVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            6839..8371
                     /locus_tag="TU818_001548"
     CDS             6839..8371
                     /locus_tag="TU818_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924347.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKGVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSGLIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            8364..9428
                     /locus_tag="TU818_001549"
     CDS             8364..9428
                     /locus_tag="TU818_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0924348.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSLKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            9430..10386
                     /locus_tag="TU818_001550"
     CDS             9430..10386
                     /locus_tag="TU818_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0924349.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGGGSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPVLGDIFFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(10424..11680)
                     /locus_tag="TU818_001551"
     CDS             complement(10424..11680)
                     /locus_tag="TU818_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEL0924350.1"
                     /translation="MEHLNNTTQLIGIKDKHITLTKAIQHDTHIEVIATLDYNPPKCK
                     LCAGKQIKYDFQKPSKIPFIEIGGFPSLIRLKKRRFQCKSCRKVTVSETTLVKKNCQI
                     SEIVRQKIAQLLLNRKALTHIASKLAISTSTVYRKLKQYHFREDYANLPEVLSWDEFS
                     YQKGKLAFIAQDFNTKKIITILDNRRQTTIRNHFFKYSKEARNKVKVVTVDMSGSYIP
                     LIKILFPKAKIVLDRFHIVQHINRALKQIRSDIMKPFDKKSLKYRALKYYWKLIQKDS
                     RKRSLKPFYSRTFRQTLTPRECLNKIFSLVPELNSYYDLYQLLLFHLQEKNAKHFFGL
                     IHDTLPHLNQTFKTALNTFSRYQDYITNAIQLPYSNAKLEATNKLIKDIKRNAFGFRN
                     FDNFKKRIYLALNITKEKTTFVFSRA"
     gene            complement(12200..13915)
                     /locus_tag="TU818_001552"
     CDS             complement(12200..13915)
                     /locus_tag="TU818_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL0924351.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMPPADADALTDYIRAIDNPFAIRLADLEKAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQDLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFKSVQVVEVQAKPDPDFSTVKSP
                     NPESQEAFTLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
BASE COUNT         4038 a         2515 c         3281 g         4195 t
ORIGIN      
        1 gtgacctatg acagccttgt cggtcagacc aggaggcact ttgatgacaa ggtcgctcag
       61 gccagaggac tggccactaa gttcaagacc gtaaaggagc agctagagga ggggatcgaa
      121 aggacaatcg ctactgacca aaagctagga ggcgactttt catgacagca ttagagaaga
      181 tcagagctgc tatccgtcaa aaggaagagg agctagagga gctgcaggag cactatcatc
      241 aagagcggct ccaaatggca gcagcccatg acgagttaag aggcaactat aaccagctgc
      301 aagagctcta tgcctctacc tatcaggccg ttagcagcta cctcagacat tatgatgcta
      361 gcctgataac agaccaatat accgttctaa cgaggctgat tgatgactat cagcaccgaa
      421 cagagcagtg ctatcacgag caaggtcgca agatgtcgca gcaggaggaa gcaattgacc
      481 atcactatcg cagccagcga caggctatag agaaggacat cacagcgctg aggcgtcagt
      541 ggcgtgaagg ttaaggaaaa ggagataaga agatgattgc tatagagatg atcttaaccg
      601 gacaagagcc gatcaggact ttaaagaaag agctggatag gagattagtt cagtccatat
      661 gtgccccctt gaccttaggt tgccttcatg cccttcaaag gcgctatgac agtgaggtat
      721 ctcggattgc cacagacacc gcagatcata ttcagaccat tgtcaatcag ctagatagca
      781 gcattagagg gcaaggcagg acagcactag agcaagcgat caagacgcag aacaggggct
      841 atagcagcct gatgtgagac aggaaggact tactgtccta ccagctacag tcactacact
      901 gctagagctt gcggtgtgag cagcagtaag aggcaaaggc gttaccccag agggattgat
      961 ggatcaccat cactagtttg gagccattag ctgtgccaaa ggttttctaa agccaaaaag
     1021 aaaaaactcc gattggagtt ttcattggtt atgtattagc taagctttgc agcaagacgt
     1081 gctttatcgc ggcttgcttt atttttatga atcaaacctt ttgattgggc tttatcaatg
     1141 cttgaagaag cagcgcggaa aagctcttca gatgggttag cttcaaatgc cttgatagca
     1201 gtacgcatag ctgatttttg tgctgaattt ttttcgtttg ctttaacgtt aagctcagcg
     1261 cgtttaatag ctgatttaat atttgccaat gttttcacct ccaaattaat ctaactacac
     1321 cattatatag aaaatatagg tgtttggcaa gcacttatca ctttttgaga taaatttcat
     1381 caattttatg gtctgcagct ttatgaagaa tgagctcagc tcgattgcgt gtaggctcaa
     1441 taaacttttc cagattttct aggttaattg ttttccagac tttttttgca aaggcaatgg
     1501 cttcattttg tggcaatgag gtatatctag tgtaatagtt agccggatca tgcttagcca
     1561 gctctaaaag gcttaagaac cgttccaaat accattgctc aatatgatgg ctatctgcgt
     1621 caatataaat tgaaaaatca aaataatcac tcatatacaa tcgattattc tgttgatttt
     1681 gaaaaacatt aatcccttcg atgatgagga agtcaggatt ggtaaaggtt tgctgctgat
     1741 caggaacgat atcataaatc tcatgcgagt aaacaggggc tgatgcggtt tgtcctccct
     1801 tgacagtatc cagaaagttt aacaatagct ccatattata ggattctggg aagccctttc
     1861 gattcagcat attgtttttg atcagtgtgc tattagggta caaaaaacca tctgttgtga
     1921 ccaactcaac agtgctggtc ttgtgtgtgc gcgccaaaag aagctgcaat aacctgctag
     1981 ttgtggactt accgacggca actgagccag aaatcccaat aataaagggt ctttgctgaa
     2041 tatctttttt tagaaagagg cttttagaaa aagacaggtt ttcttgagcg attttataga
     2101 cttgaatgag atgaatcaag ggaaggtaaa cctcaacaac gtcgttgata tcaatattat
     2161 cattcaaact ggtgatgcta gtaagctcct cttgagtcaa taagggcttg cttttttgat
     2221 gtaattgctt ccaggatttt ctggaaattt tttcaaaagt aataaattcg tttgacatag
     2281 ttactcctac taattggcag tgcttacatt ataacatgtc aataaaaaaa ttgaaaaatg
     2341 tttcgtctga aattcttaaa aaaacactga aaaaccctat aaaaatcgaa caattttagc
     2401 ctaacaattg gctaatataa agttaatcgg tcaatgttcg gaatatatgg ttcgataaac
     2461 gaaaaaccaa gaaaaacaaa cgtcttgtaa accatttcaa agtgtgatag aatgaaaaag
     2521 catcgaaaaa agataggaaa acacatgaca aaaatgtatt atgatgaaaa tccagatagt
     2581 gctcatgata tccatcaatt gacggtcaat ttgttaggac agtcctttac ttttttgaca
     2641 gattctggtg ttttctcaaa aagaatggtt gattttggaa gtcaggtcct gctcaacaca
     2701 ttagattttc aagaaggtga tcgtctgctt gacttgggct gcggctatgg gccgctagga
     2761 cttagcttgg caaaggctca aggtgttgag gcgactctag tagatattaa tcatcgcgct
     2821 gttggcttag ctaagcagaa tgctgagagt aatcaggttg aggcgaccat ttttcaatca
     2881 aacctctatg acggtgtgac agggacattt gagcacatca ttagtaaccc acctattagg
     2941 gcagggaaaa aagtggttca tgagattatt gaaaagagta ttgatttttt aactaaaggc
     3001 ggtgatttga cagtcgttat ccaaaagaag cagggagcac caagtgctaa agacaaaatg
     3061 gaggccgttt ttgggaatgt gactattctc aaaagagaaa agggttacta cattttaaga
     3121 agtattaagg aaaggaattg agctcaagtg taaaaagtgg tattaaaaag catagcggta
     3181 ttttagtaag agttgccttc taatatcact attttctcag agcttttggt atcttgttga
     3241 tgagagcagt tgatttaatc caaaaaaagc gtgatggtaa agagctatct accgaagaga
     3301 tccagtggct gattaatggt tatgccaatg gtactgtgcc agattatcaa atgtcggctt
     3361 ttgcaatggc gatctatttc aagggaatgt ctacacgaga aactcgcgat ttgaccatga
     3421 gtatggttga gacaggtgag cagattgatt tgtcagctat agctggtatc aagacggaca
     3481 agcactcaac aggtggtgtt ggtgataagg tgacactcat cttagctcct ctagttgcta
     3541 gctttggcgt tcctgtagcg aaaatgagtg gacgcggctt aggccacacc ggtggaacgc
     3601 ttgataagct agaatctatc aagggctttc agattggtcg gacccaagag gaatttatca
     3661 agcaggtaca agagatcgga ctttcagtta ttggacaatc agataagctt gtgaaggcag
     3721 ataagctgct ttatgctctt cgtgatgtga cggcaaccgt tgatattgtt cctttgattg
     3781 caagctctgt tatgagtaag aaaattgctg ctggcgctga tagtattttg ctagatgtta
     3841 ccgttggtga cggtgccttt atgaagacta ttgaagatgc tgagaagctg tctagactga
     3901 tggttgacct tggtaaggag gttgggcgtc agacagtggc tgtcattaca gatatgagtc
     3961 agcctcttgg tcgtgctatc ggtaatcgct tagaggtgct agaggcaatt gatatcatga
     4021 aaggcaaggg acgcaaggat attactcact ttatttgtga gctagctcag attatgctgg
     4081 agcttgctgg tgctcaacac tctcttgagg atattcacca tcatttggtt ggcggagcag
     4141 ccttaaaaaa attagaagag atggttgttt atcaaggagg tgatcttgag gacctttatc
     4201 gtccatcaca ggcggctgtt caaacagagg tttttgcgtc agaagatggt tacatcacag
     4261 cattgcctgc tcttgagttt ggattgtttg caatgaggct gggtgctggt agagcagtca
     4321 aaacagatag tctggattat gaaacaggga ttgtctttga caagaaggtt ggtgacgctg
     4381 tcgctaaggg agagcgcatt gcagttgtct tttcacagga agccctagac gaaaaaatgc
     4441 ttacagaatt tgaaaaaaat gttaaaatag gggcggaaca cctagaggct aacgaaatta
     4501 tcaaaatcat ttcctaagga ggagtataac atgaatatta acaagtatat tgaccacaca
     4561 ctactaaaag ctgacagcgt tcaatcgcag cttgaccaat taattgagga ggctaaagcc
     4621 tatgactttg ctagcgtttg cgtcaaccct tgctgggtag cctatgctgc aaaggcttta
     4681 aagggaacag atgttaaggt ttgtacagtt gttggttttc ctttaggtgc aactacctca
     4741 gcaacaaagg cctttgaaac aaaggacgct attgaaaatg gtgctgatga gattgatatg
     4801 gttatcaata ttggtctgtt aaagcagggt gactaccaag ctgttgaaga tgatatgcgt
     4861 gcagtggtag aggctagcgg agacaaatta gtcaaggtga ttatcgaggc ttgcctcttg
     4921 actgatgatg aaaaggttaa ggcttgtcag ttggcggtaa atgcaggtgt tgactttgtg
     4981 aagacctcta ctggtttttc aactggcggt gcaaccgttt ctgatgtcaa gctaatgcgt
     5041 caaacagttg gtccagacat tggcgtaaag gcagctggtg gtgctcgttc tctagaggac
     5101 gctttagctt ttgtcgaagc aggagctaca cgtattggaa cttctgcagg ggtaactatt
     5161 atgaaaggtg aagttgccaa tggaggctac tgatttagtt tcgttagcca ttgaagctag
     5221 taaaagggct tatgtgcctt actcacattt cccgatcgga gctgctttaa agacaaagga
     5281 cggaacaatc tatactggca ataatatcga gaatgccagc tttggcttga ccaattgtgg
     5341 ggagcgaaca gctattttta aggctgtttc tgagggacat cagcagcttt tagaaattgc
     5401 catttatgga gagactgatg agccaatctc tccttgtgga gcctgtcgtc aggtcatggc
     5461 agaatttttt gaagccactg ctccagtaac gctaattgct aaggacggtc gtaccatgcg
     5521 cacaactgtt ggcgagttac ttccttattc gtttacagat ttatcgtaat ctggcttaat
     5581 tttgttatct agccattagg ctttatattt actttcggca attggtttgc tagaaatatt
     5641 tttaggaggg ttcatattca tgaacaagaa atttattggt gttggtttag cttctgtagc
     5701 tttattaggt ttagttggtt gtggtaatcg taacgcttca aagggatctg gtgatgctaa
     5761 aacagatttg aaggtagcag tggttactga cactggtggt gttgatgata agtcatttaa
     5821 ccaatcagct tgggaaggct tgcaggcttg gggtaaggac aatggactaa caaagggttc
     5881 aggctttgat tacttccaat ctacaaacga gtctgaatat gcaactaaca ttgatacagc
     5941 agtttctagt ggttatgagg ttgtttatgg tatcggattt gccttgaagg atgcaatcag
     6001 taaggctgct gatgacaaca acaaagtaca atttgttatc attgatgatg ttatcgaagg
     6061 caaagacaat gttgctagcg taacatttgc tgataacgaa gctgcttacc ttgcaggtat
     6121 tgcggcagct atgactacaa aaacaaaaac agttggtttt gtaggtggta tggaaggaac
     6181 agttgttaca cgctttgaaa aaggctttga ggcaggcgtt aagtctgttg atgactcaat
     6241 caagatcaag gtggactacg ctggatcatt tggagatgcc gctaagggta agacaattgc
     6301 agcagcgcaa tacgcagcag gtgctgatgt tatctatcag gtagctggtg gaacaggtgc
     6361 gggtgtcttc aacgaagcaa gaacaattaa cgaaaaacgt gacgaagctg ataaggtttg
     6421 ggtaattggt gttgaccgcg accaaaacga agaaggtaaa tatacatcta aggatggcaa
     6481 atcatctaac tttgtacttg catctactat aaaaggtgtt ggtaaggctg ttcaattgat
     6541 caataagcag gcagcagata agaaattccc tgcaggtaaa acaactgttt atggtctgaa
     6601 ggacggtggt gttgagattg ccacaacaaa tctttctaaa gacgttatca aagccatcga
     6661 agaagcgaaa gaaaaaatta aatctggtga cgtaaaagtt cctgaaaagt agttactgga
     6721 aaagagcgac cttcgtcggt cgcccttttt agagtggaac accttttgct tcagtaaagg
     6781 ttgtgacaaa tggctggctt tactgaaaca aaagattaaa ttgaaaggaa ataatcctat
     6841 ggcacagcat gtcattgaaa tgaaagagat tacaaaaaaa tttggtgatt ttgttgcgaa
     6901 tgaccatatt aatttgaatg tcagaaaagg cgaaattcat gcattgttag gagagaatgg
     6961 tgcaggtaaa tcaacgttaa tgaatatgtt agctgggctt ttagagccaa ctagtggaaa
     7021 cattgtcatt aacggtcagc ctgttgttat tgactctcct tccaaatctg ctagattggg
     7081 tattggaatg gtacaccagc actttatgct agtagaagct tttacagttg ctgagaatat
     7141 cattttagga aatgaagttg tcaaaaacgg ttgtcttgat ttaaaaaagg ccagcaagga
     7201 cattaaagag ctttctgaga aatatggttt agctgttgat cctactgcca agattgctga
     7261 tatttctgta ggggcacagc agcgtgttga aatcttaaag accttatatc gtggtgcaga
     7321 tattcttatt tttgatgagc caacagctgt tttaacgcct gctgaaatac aagagctcat
     7381 ggaaatcatg cgtaaccttg ttaaggaagg caaatccatt attttgatta ctcataagct
     7441 ggacgaaatt agagcagttg ctgatagagt cactgttatt cgacgtggga aaagtattca
     7501 aacagtagat gtagcaggtg caacctctca ggacttggct gaaatgatgg ttgggcgttc
     7561 agtttccttt acaacagcta aaaaggcagc agagccaaaa ggggtggtgc tgtcgatcaa
     7621 gaatttagag gtcgatgaaa atcgtggaat cccagcagta aaggggcttt ctcttgacgt
     7681 tagagctggt gaaattgtgg ggattgcagg gattgatggt aatggtcagt cagggctgat
     7741 tcaggccatt acaggcttga gaaagactag atctggtagc attacaatca aaggtcagga
     7801 ggttgttcat ttaagctccc gtaaaatcac agagctatca gtggggcatg tgcctgagga
     7861 ccgtcataga gatggcttag tgctggacct ttccttggct gaaaatactg cccttcagac
     7921 ctattataaa gagccactaa gtaagaacgg tattttaaat tacaatacaa tcaatgatta
     7981 tgctcgtaga ctgatgaagg aatttgacgt tcgtggtgcc aatgaattgg ttccagctcg
     8041 tggattttct ggcggtaacc aacaaaaggc tatcattgca cgtgaggttg accgtaaccc
     8101 tgatttattg attgtcagtc agccaactcg cggcttggac gttggtgcta ttgagtacat
     8161 tcataagcgt ttgattgaag agcgtgacaa aggcaaggcc atcctcgttg ttagctttga
     8221 gcttgacgaa atcttgaatt tatctgaccg tattgcagtt attcatgacg gtaaaattca
     8281 aggcattgtg ttgcctcaag ataccaataa gcaagaattg ggaattttga tggctggtgg
     8341 ttccattgat aaggaggaga gtcatgtcta aaaatgcaca aaagattgct gtgccaatga
     8401 tttctatctt gttaggattc ttacttggcg ctattgtcat gtttatcttt ggctatgatc
     8461 caatttgggg ctatgagggc ctatttcagg tagcctttgg tagtatcaaa aatattggtg
     8521 aaatcttcag agcgatggga ccactaatcc tgattgcact tggttttacc gttgctagcc
     8581 gtgccggctt ctttaatgtc gggctgtcag gtcaagcttt ggctggttgg attgctgcgg
     8641 gctggtttgc tcttgtcaat cctaatatgc ctcgtccgct tttaattctg atgactgtct
     8701 tgattggtat ggttgccggc ggaattgctg gcgctattcc aggtattttg cgagcttatc
     8761 ttggtacaag tgaagttatt gttaccatta tgatgaatta tattattctg tatgtcggta
     8821 acgctatcat tcaaagaggc taccctgaaa gtgttaagca aagtattgat tcaaccatac
     8881 aggtcagtga taatgccagc tatcaaagtc aatggctgtc agatttaacc aataattctc
     8941 gtattaatat cggtatcttt tttgcgctta ttgcaattgc agttatttgg ttcttactaa
     9001 acaaaacaac cctcggattt gaaattcgtt cagtaggtct taatccacat gcttcagaat
     9061 atgcaggtat gtccttaaag cgtacgatta tcctatcaat gatcatttca ggtgctttag
     9121 caggcttggg aggagttgtt gaaggcttgg gaacctttga gaatgttttt gtacagggaa
     9181 gctctctagc aattggtttt gacggtatgg ctgttagctt gcttgctgcc aattcaccga
     9241 ttggtatctt cttctcatca ttcctatttg gggtgttgag cataggtgct cctggtatga
     9301 atatcgcagg aattccacca gaattggtaa aagtagtgac tgcctcaatt atcttctttg
     9361 taggtgctca ctaccttatc gaacgctata ttatcaggcc taaaaaacta gtaaagggag
     9421 gtaaataaga tgagtttagt tactattttt gctttattgg tttcatcaat gcttatctat
     9481 gctacacctc ttatttttac aagtattggt ggtaccttct cagaacgagc tggtgttgtc
     9541 aatgtcggcc ttgaaggcat tatggtcatg ggggggggtt caggcattgt ctttaatctt
     9601 gaatttgctc atatctttgg taaagctact ccctggcttg cagttttggt gggaggagtt
     9661 gttggattga tcttttcatt gatccatgcg cttgcaacga ttaactttag ggcagatcac
     9721 attgtcagtg gtacagtgct aaatctgctg gcaccatcgc ttgccatttt cttagttaag
     9781 gtgatgtacg gtaaggggca aactgataat atccagcaat cattcggtaa gtttgatttt
     9841 ccgattctct caaaaattcc agttcttgga gatatattct ttagaaatac tagcttagtt
     9901 gggtatttag ctgttgcctt ttctttccta gcttggtttg tgctttacaa aacaagattt
     9961 gggttgcgtt tgcgctctgt aggtgaacac cctcaagcag ctgatacact tggtattaac
    10021 gtttacctca tgaaatatta tggggttatg atctctggtt ttcttggggg tattggtgga
    10081 gctgtctatg cacaatccat ctctgttaac ttcgcagtga caaccatttt aggacctgga
    10141 tttattgccc ttgccgctat gatttttggt aagtggaatc cggtaggtgc tatgctatct
    10201 agcttgttct ttggattatc acaaagctta gcagttattg gggcacaatt accagtattg
    10261 gaaaaaatcc caacggttta ccttcaaatt gcgccatacc tattgaccat catcattttg
    10321 gctgctttct ttggacaagc agtggctcca aaggcagacg gtgttaatta catcaaatca
    10381 aaataaaaaa agctcaatgt caactgtagt gggtgactga tagctaagca cgagagaaga
    10441 cgaatgtcgt cttctctttt gtgatattca aagcgaggta gatacgtttt ttaaagttgt
    10501 caaagttccg aaatccgaaa gcattgcgct tgatatcttt gataagtttg ttagtggctt
    10561 ctaacttagc gttagaataa ggcagttgaa tggcattggt gatgtaatct tggtagcgac
    10621 taaaggtatt tagagctgtt ttaaaagtct gattaagatg tggtagtgtg tcatgaatta
    10681 aaccaaagaa atgcttggca ttcttttctt gcaggtgaaa aaggagcagc tggtacaggt
    10741 cataataaga gtttaactca ggcactagtg agaagatctt attgagacat tctctaggag
    10801 ttaaggtttg tctgaaggtg cgggaataga aaggcttaag agaccgtttt ctgctatcct
    10861 tttgaataag cttccagtag tacttaagag ctctatattt aagagacttc ttgtcaaatg
    10921 gtttcatgat gtcactacgt atttgcttga gagctctatt gatgtgctgg acaatgtgaa
    10981 aacgatcgag aacgatttta gccttaggaa atagaatttt aatgagagga atataacttc
    11041 cagacatatc gacagtgacg actttcacct tgtttctagc ctctttagag tacttaaaga
    11101 aatgatttcg gatggttgtt tgacgtctat tatcaagaat ggtaatgatt ttcttagtgt
    11161 taaaatcctg agcaatgaag gctaatttac ctttctgata agagaactca tcccaagaga
    11221 gaacttctgg caaattggcg taatcctctc ggaaatgata ctgcttaagc ttgcgataga
    11281 cggtagaagt ggagatagcg agcttagaag cgatatgggt gagagccttt ctgttgagta
    11341 aaagctgagc gattttctgt ctcactatct cagaaatttg gcaatttttc ttaaccaggg
    11401 tagtttcaga tacagtgact tttcgacagg atttgcattg aaaccttctt tttttcaaac
    11461 gaatgagact aggaaagcct ccaatttcga taaagggaat tttagagggc ttctggaagt
    11521 cgtatttgat ttgttttccc gcacacagtt tacatttagg agggttatag tctagtgtag
    11581 cgatgacttc aatatgagta tcatgctgga tagctttagt caaggtgata tgtttgtctt
    11641 tgattccaat gagttgtgtg gtattattga ggtgttccat aagatacctt ctaaatgata
    11701 gtttagtcgc ttttcatgat aagtcttatg ggactttttt gatactcaaa aagccctata
    11761 atctccacag tagccttacc cactacagaa attatagagc catcttagaa cactggactt
    11821 gttcgctttt taatgaatta aatttagtag atcctttaaa ggcatgctat caagcttttt
    11881 atccttgact tttgtttagc aagtgaagtg ttcacaaaag ctagctaaaa cactgagctg
    11941 acaatgtaga gaatggctcg ttttgacaag gttagagtgc tttttgctgt atggttttta
    12001 atccacgcac ctgaaaaaga aaggacagga cctgtgcgag cttacttgtg gttagtaggt
    12061 ttcaattcat gctcccaaaa aggaagcaac gcaactctga gaaaggtctt agaccacttt
    12121 cccagtttgc ctcacagcta atggtgtaaa acaaatagac caccctgtaa caggtggtca
    12181 tggttagata tcagctcatt taagagacaa aggcgttgat ttcagattca atattggcaa
    12241 ttttttcttc ggcaagcgca agggtgtcac caacagttgc gatataaaat ttaatttttg
    12301 gctctgttcc tgatggtctt acagcaaacc atgaatcatc agctagggta tattttaaga
    12361 cattgcttgg aggagtggtt agctgggttt gaccagcttt atgagttgcc gtctgactga
    12421 ggaaatcctc tgttaacaca atatcagtgt gattaaactg cgcaggggca tgcttgcgga
    12481 atttatccat aatctgtttg atttcagctg cgccatcaac accagacagt gtaacagaaa
    12541 tggttttttc tgcaaagtag ccgtattctt tgtaaatgtc atcaatacca tcagcaaggg
    12601 ttagtccacg agagcggtag taggcagcaa tctcagccac caatagcacc gcttgaatag
    12661 cgtccttatc acgtacaaat ggtttaatga gataaccaaa gctctcctca aagccaaaca
    12721 tataggtgta attgtgcttt tcttcaaatt cttgaatttt ttcagcaatg aacttgaagc
    12781 ctgttaagac attaaacatg gttgccccgt agctctctgc aattttagtc actaattcag
    12841 tagagacaat ggatttggca agagcggcat tgttaggtag ggttccagcc tgctgatgtg
    12901 cttctaaaat atacttagca attaaagcac caatttggtt gcctgatagg ttgcgatagc
    12961 tgccatctgc ctgccgaatt tcaaccccaa gacggtcagc atctggatca gtagcaacaa
    13021 gaacatcagc atcaacctga cgtccaagct cctcagcaag agtaaatgcc tcttgacttt
    13081 caggattagg agatttgacg gtagaaaaat ctggatctgg cttagcctgc acctcaacca
    13141 cctgaacgga cttaaagcct gcttgtgcca aggcacgacg tgctagcatt tcacctgttc
    13201 catgaagagg tgtatagaca attttcatgt cacgaccata gtcattgatg aggtcttggt
    13261 tgatattgac ctttttgacc tcttctaaat aagcaaggtc aacagcttca ccaataacct
    13321 cgatgagccc attagctttg gctttctcta aatcagcaag cctaatggca aaggggttat
    13381 caatcgcacg aatgtaatct gttagagcgt cggcgtcagc tggaggcatt tgaccgccgt
    13441 cagacccata aaccttatag ccgttgaatg gtgcagggtt gtgactggca gtaaccatga
    13501 taccggcaaa agcacccaaa tgtcgcacag caaaggaaag ctcaggtgtt ggccgaaggc
    13561 tttcaaaaac gtatgattta atgccatgag ctgctagtac ctgtgcagat tcaaaggcaa
    13621 attctggaga aaaatgacga gaatcatagg cgatagcgac accggccttc ttagcagctt
    13681 ctccctttga ctcaactaat gctgccaagc cctcagttgc ttggcgaaca acaaaaatat
    13741 tgatacgatt cgttccagcg ccaatatagc cacgcatacc agctgttcca aattcaagat
    13801 tggtgtagaa ggcatcttcc tttgtttttt cgtccatgct aagtaattca tctcttaaat
    13861 aggctggtag atctggaata tcaagccatt tttgatagtt ttctgtgtaa gtcatagtat
    13921 tctcctttat atttttaacc gctttcatta tatcatgttg aaaaggaaaa atcacttatt
    13981 ttctgtaata gcttccaatc attttttcac ataaggatca atttccttg
//
LOCUS       DARYMD010000050        13283 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYMD010000050 DARYMD010000000
VERSION     DARYMD010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13283
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            304..1848
                     /locus_tag="TU818_001553"
     CDS             304..1848
                     /locus_tag="TU818_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0924352.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVSENIRFPLFILVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPKFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTILFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKTYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            1932..2960
                     /locus_tag="TU818_001554"
     CDS             1932..2960
                     /locus_tag="TU818_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL0924353.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVSLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGLYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFDEADWFHVSGITPALTSDLYELTYYLMTKARAEGL
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGALDLKDQLGLNRP
                     YDDEALLKEVLARLADTYGVKCFAFTQREMDYTNEYLLKAYLYQNGSLYKTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSYKDEQATLDVAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            2981..4771
                     /gene="uidA"
                     /locus_tag="TU818_001555"
     CDS             2981..4771
                     /gene="uidA"
                     /locus_tag="TU818_001555"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL0924354.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGQHKG
                     GFTPFEVLVPETHYQDNQIKVSVCANNILDYTSLPVGNYSEETQEDGSIKKIVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVAQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLIKGEVGLRQELLEWQKKFPNKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            4813..5484
                     /locus_tag="TU818_001556"
     CDS             4813..5484
                     /locus_tag="TU818_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL0924355.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAHDAMLLHIMTVKR
                     TAFLS"
     gene            5667..6284
                     /gene="eda"
                     /locus_tag="TU818_001557"
     CDS             5667..6284
                     /gene="eda"
                     /locus_tag="TU818_001557"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL0924356.1"
                     /translation="MLNRLKENYFFAIIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRILSAEFEHDDAVIIGAGTVMTPDLAREAIAAGASFLVSPHFSREIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            6312..7709
                     /gene="uxaC"
                     /locus_tag="TU818_001558"
     CDS             6312..7709
                     /gene="uxaC"
                     /locus_tag="TU818_001558"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL0924357.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     VMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGK
                     MAQDIAYNNAIQYFN"
     gene            7971..9065
                     /locus_tag="TU818_001559"
     CDS             7971..9065
                     /locus_tag="TU818_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL0924358.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRIVEAAGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDFSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKIPDFGITVKTVGDK"
     gene            9081..9920
                     /locus_tag="TU818_001560"
     CDS             9081..9920
                     /locus_tag="TU818_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL0924359.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIAKAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            10184..10987
                     /locus_tag="TU818_001561"
     CDS             10184..10987
                     /locus_tag="TU818_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL0924360.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQA
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEYAGVTGIDALKQWVQHTASLSNQSLEAEL
                     LKRPSDDLQKALDWSNEVNRQIEAYKGEALAFLGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVGKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            11102..12892
                     /locus_tag="TU818_001562"
     CDS             11102..12892
                     /locus_tag="TU818_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL0924361.1"
                     /translation="MTHLVDLRKKPYSLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGVNVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMVLINTPEAQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKELLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
BASE COUNT         3641 a         2453 c         3245 g         3944 t
ORIGIN      
        1 gttggtgggg tgacgatact gacctcaaag gggttggata agtattggta aaaggcttga
       61 gctctgtctt gtgcagggct cagttttttt gatgtcaatg agtaattgtc tgatgattat
      121 ttttaaagac accagaaatt atcagatgaa tttaatgatt aaaatcctaa ataagcttta
      181 ttttttaaaa ttaggcgaaa aaagtttaaa ttgtgttgac aaatcatcag atgaatagta
      241 agataagcat gtagaaataa aacgcttaca caataagcga atgataaaag ggggatttct
      301 ctgatggaga aaacaattga ccaaagggtt gaagaggtta cctataaccg cgctaaggtt
      361 tggcagcttg ttttatttgc tttaaacaat gcttcaacca atatctacct attcacattt
      421 atgtttgtga cctacttttc aacaggtgtt ctaggcttgg cagctatttt tgtcagccag
      481 atcatgggtt atattcgtat ttttgatggc tttattgatc ctgcgattgg tatcttgatt
      541 gataaaacag aaactaagtt tggtaagtat cgtccgatcc taatcatcgg aaatattatc
      601 acagccctat cacttattct gctgcttggt ctaagtggag ttagtgagaa cattcgtttt
      661 ccacttttta ttctggtttt gattatccat aagatcggct actctatgca gcaaaccatc
      721 actaaggctg gtcagacagc ccttactaat gatccgaagc agcgtccaat ctttaacatt
      781 gttgatgcca ttatgacaac cttgctgatg actggtggac agtttgttgt gtcaagcttc
      841 ttggttccaa aatttggtaa cttcacacca gccttcttcc acgtgttgat ttatggcacg
      901 attgttatct cagctatttt gggtctattg gcagtgcttg gtatttggag caaggacaga
      961 aaggaattct ttggtcttgg tgaaaatacg caaaagacag ctctgaagga ctatttgaag
     1021 gttatcaagg gcaaccagcc gctacaggtc ctatcaattg ccgcagcctt ggttaagttt
     1081 gctgttcaat tctttggtga ttcggttgtc atggttatct tgtttggtgt tttatttggt
     1141 aactatgctt tgtctggtca attctcattg ctgtttattg ttccggggat tttgattaat
     1201 attgcttttt caggtattgc tcgtaagaga ggtttgcgtt tctcatatat cagagctctt
     1261 cagattggct tggttggctt gttagccttt ggtattgtgc tctttatggg taataaaggg
     1321 gatctcagcc taagtcatat taacctttac actattttgt ttactgtgac actgattatt
     1381 gctcgctatg cctcacaagc gcctgctagc ttggtgctaa caatgggagc tgatatttca
     1441 gactacgaaa catcagaatc aggccgttat gtctcaggaa tgattggtac aatcttctcc
     1501 ttgactgact cgattgcatc atcatttgcg ccaatggtta ttggtgcagt gctggctggt
     1561 attggttttt caaagactta cccaacgatt gagacaccgc ttaccccaag tctaaagatg
     1621 gccttgattg cgctgcatgt cggtattcca tttgtagcct tactagtggc tttgattttg
     1681 atgtcattct acaagcttga caaagaggaa atggtgcgta ttcaagagaa gattcaagtg
     1741 atgaaagcaa gctctgataa ggaacgcgtg caggctatcg ctaaaaatgt accactgtca
     1801 gacatggact atgttgatgt gacaaaatat cctgttgata aggattaggt gctgggtcag
     1861 ctatttcttt gaggagtggc tgactttttt ataaaataat agagtagctt gatagtataa
     1921 ggaggaatgt tgtgaaaaaa gttgtatcct tgggtgaaat cctcttgcga ttgtcacccc
     1981 ctcaatacca gacgttaaag caggcaacaa gcctagattg tcaatttgga ggttctgagc
     2041 ttaatgtcat ctcaagcctt gctcagctag ggcatcaggt ctctcttatt tcagctattc
     2101 cagacaatga tctgggacaa atgacaaaaa cctttctctt ttcgcgtcaa attaatcagg
     2161 agcatattat cgaaaagggt cagcgtttag ggctttatta ttatcaaaag ggcttttctt
     2221 tgcgagcaag tcgggttacc tatgaccgct gtcattcagc cttttgggag tcaaagcgtg
     2281 ctgactatga tttggagcat gtttttgatg aggctgattg gtttcatgtg tctgggataa
     2341 cgcctgctct aacgagtgat ctttatgagc tgacctatta tttgatgaca aaggctaggg
     2401 cagagggatt gactatttcc tttgatttga attttagggc tagtctatgg tcctcctttc
     2461 aggaggctag agatctcttg tcgcctcttg ttcagctggc tgatgtttgt attggcattg
     2521 agccgctgac gcttaaggga agcggcgcgc ttgatttaaa ggatcaatta ggcttgaata
     2581 gaccctatga tgatgaagcc ttgttgaagg aggtgctggc taggttagct gatacctatg
     2641 gggtaaaatg ctttgccttt acccagagag agatggacta taccaatgaa tacctgttaa
     2701 aggcctacct gtatcaaaat ggcagccttt ataaaaccca aaaatctggt attcaggttc
     2761 tggaccgagt agggacgggc gatgctttta cggcagggct gattcatggc ttattaagtt
     2821 ataaagacga gcaggctact ttagatgttg caatggctag ctttaagttt aagcatacca
     2881 ttgagggtga tagtaatatc atgacacaag atgacattga tcatttactg gccaaggaat
     2941 cgcatgagat tcaacgataa tgtgataaag gagaaatcgt atgttatacc caatactgac
     3001 aaaaacaaga aagatttatg atttaggggg gctctggcaa tttaagctag gagaccataa
     3061 cccgcaggag ctcctagcct ctgatgagct gatggttgtg ccgacctcct ttaatgatgt
     3121 ggttgtggat aaggacaagc gcaattacat cggtgatttt tggtacgagc gctttgttga
     3181 tgtgccagat cttgctgctg atgaggagct ggtacttcgc tttggctctg tcacgcacaa
     3241 tgcaacagtc tatgttaatg ggcaagcttt agggcaacac aagggaggct tcactccatt
     3301 tgaggtgttg gtgcctgaga cccattatca ggataatcaa attaaggtat ctgtttgtgc
     3361 caataatatt ttagattata ccagccttcc agtgggcaat tatagtgaag aaactcaaga
     3421 ggatggcagt atcaaaaaaa ttgtcaagga gaattttgac ttcttcaact atgctggtat
     3481 tcaccgtcca gtgaagctta tggtgcggcc aaaatgccat atctcagata tcacgatcac
     3541 gagtgacttg tctgaggata tgacatcagc cttagtcgag gtatctgttg aaacctcagc
     3601 agctgttgat gaggttaagg tgacgatctt tgatgaagag cacaagctcg ttgcgcaggc
     3661 tattgatggc aaggcaagac ttgataaggt tcgtttatgg gaagttttag atgcttatct
     3721 atacactgcc cacgttgaga tcatcgtaga tggcaatgtt gtagatagtt atgatgagcc
     3781 atttggtatc agaagtattg cagttgaaaa aggacaattt ttactaaatg gcaagcctgt
     3841 ttatttcaag ggctttggta agcatgagga tacctttatc aacggtcgtg gattgaatga
     3901 agcagctaat ttaatggata tgaatctgct caaggagctt ggtgccaatt catttcgtac
     3961 ctcacactac ccttactctg aggagatgat gcgtctggca gatcgtatgg gaatcttggt
     4021 tattgatgag gttccggcag tagggctctt ccaaaacttt acagcctcct tggatctttc
     4081 gccaaaggac aatggcactt ggtctgtcat gaaaactaag gaagcgcatg agcaagcaat
     4141 tcgtgagctc gtcaagcgtg acaaaaatca cccttctgtt gtcatgtggg tcgtggccaa
     4201 tgagcctgcc agccatgaag agggagcaca cgaatacttt gagccgctga ttgctcttta
     4261 taaggcacta gatccgcagc agcgtccagt aacattggtt aatctgctat tagcaacacc
     4321 tgatcgagat aaggtgatgg atctggttga tgtgatctcc ttaaaccgtt attatgcttg
     4381 gtatgttgat catggagact tgatcaaagg agaggttggg ctgcgtcagg agctattaga
     4441 atggcagaag aagtttccta acaagcctat cctgatgaca gagtacggtg cagatacgct
     4501 tcctggtctt cattcgatgt gggatattcc atatacagag gaatttcagt gccgcttcta
     4561 tgagatgagt caccgcgttt ttgatgagat tcctaatcta gttggagagc aggtatggaa
     4621 ttttgctgat tttgaaacta atctgatgat cttccgtatt caaggcaatc ataaggggct
     4681 tttttctaga aatcgccagc ctaagcatgt tgttggtttg tttaaagagc gctggaatac
     4741 cattccccac tacaattata aaaagaaata gtgtacaata gtagctagca ataagtagga
     4801 agaagggatt gtatggctag gcctttagtc gaaaaaacag cagagcgctt gttaaagcta
     4861 attttagaac gtgggtatga ggttggagca aagctcccca atgaatatga gttagcacag
     4921 gacttagagg ttggaagaag cactattaga gaagctgtta gaagcttagc aactagaaat
     4981 gttttagagg ttagacaagg atcaggtact tatattagct cgaaaaaagg tgtttctgag
     5041 gatcctttag gcttttcctt agtcaaggac acagccaagc tgaccgctga tttgtttgaa
     5101 ttgcggctat tgcttgagcc taggattgcc gctttgacag cacagcatgc aacgccaaag
     5161 gaggttgaag ccttagagaa gcttgttgtt gatattgaag aggccgtagc tgctggtgat
     5221 cctaagcatt tgcagctgga tgtgaatttc cattccttga tggcaaaata cagtggcaat
     5281 attgctatgg atagcttgct accggtgatc aatcagtcga ttcatctgat caatgccaat
     5341 tacacaaatc gtcagatgaa agaagattct ctacaagccc acagagatat tctgaatgcg
     5401 attaaagcgg gagatccgat cgcggcacat gacgctatgc tcctgcacat catgacagtt
     5461 aagcgaacgg cttttctatc ataagcttaa gcttgcttgc cggaaacagt ctattgagtt
     5521 ttgagtgatt tgcttcttgg ctcgaataag agggcttggt tttagagata ctagaaccaa
     5581 gtcctttttt tgctttttcc ttgacaaatc atctgatgat ttatataata aaactaagac
     5641 aacggtttca tgaaaaggag gagcctatgc taaaccgatt aaaagagaat tatttttttg
     5701 ctattattcg tggaaaaaca gtagaagacg ctattgccat tgctaagcat gctattttag
     5761 gcggtattcg taatatcgag attacctatt ctactccaaa tgcttcagag gttattagaa
     5821 tattgtcagc tgagtttgag catgatgatg ctgtgattat tggagctggg acagtgatga
     5881 cgcctgatct ggcaagagaa gctattgcag caggtgctag ctttttagtt agtcctcatt
     5941 tttctagaga aatagcagag gttgccaatc aggcatcaaa tctttatttc ccaggctgtg
     6001 caacagctac tgaaattgtc acagcaatga atgcctcttg tccgattatt aaggtctttc
     6061 ctggaggtgt tgtaggacca ggctttatta aggatattca tggtcctatt cctgaggttg
     6121 atttgatgcc atcaggtggt gtgtcgattg acaatgtcaa ggagtggaaa aatgcaggtg
     6181 ctgttgctgt tgggattggt tcagccttag ctagccgagt tgaggctgag ggctatgata
     6241 gtgtaacccg tattgcagcg tcatttgtat cagcccttga ttaagggaat tggtcataag
     6301 aggaggacga gatggctttt aatgacgaca attttatgct aaaaaatgag gcagcaaagc
     6361 gcctctatca acaaatcaag gatcagccta tttttgatta ccattgtcac ttagatccaa
     6421 aggaaatttt tgaggacaag gtttatgaca atattgttga cctttggctt ggtggtgatc
     6481 attacaagtg gcgcttgatg cgcgctaatg gcatttcgga agaagaaatc acaggctcag
     6541 cctctaagct ggataaattc aaggcctttg cccgtacact tcagcgctcc tatggcaatc
     6601 ctgtttacca ctggtcagtg atggagttga aaaatgtctt tggtgtctgt gagctactga
     6661 ctgaggataa tgcagaggaa atctatcatc gtatcaatgc ttacttggtt gagcaccaga
     6721 ttagtcctag aaagttgatt gcagatagcc gagtgcggtt tattggtacg acagatcacc
     6781 cgcttgatga cctagcttgg cataagaggt tagctgctga tgataccttt gagacggttg
     6841 tcgcgccaac ctttagacca gatgaggctt ttattgagca tcagcgcttt gcagattttg
     6901 tggctcgtct tgctcaagct accggaagaa ctattacaga ttttaagagc tttatagcgg
     6961 ctatggaaga gcgtattgcc tattttgcag aaaatggttg taaggccagt gacatcagct
     7021 ttacagagat tgtctttgaa gcagcagagc cagagcaatt agaccgtctc atgacaaggg
     7081 ttttagaggg ctatcagccg cagccgttag aggtcaagca atggcagaca gcggtgtttg
     7141 cagagctttg caggctttat aagcactatg gctttgttac tcaggtgcat tttggtgctc
     7201 ttcgcaataa tcattcagct atattcaaca agctgggggc agatgtgggt gttgactcac
     7261 tgggagacca aacaggacta gcaatcaata tgaatcgcct gctggatcat ctggtgcaaa
     7321 gagacagcct gccaaagatg atttggtata acctaaatcc gagctataat atcgcggttg
     7381 ctaatacact agctaatttc caagccaatg aaaacggtat tgcgggctat ctgcaattcg
     7441 gtgcaggctg gtggtttgct gataccaagc ttggtatgat tagccagatg aatgccttgg
     7501 ctgagcaagg tttgttagct aattttgtcg gcatgctaac ggattcacgt tcatttttat
     7561 cctatcagcg tcatgattat ttcagacgta ttttgtcgac ctaccttggt gagtggattg
     7621 aagaaggtga ggtaccagag gattatcagg cacttggtaa aatggctcag gacattgcct
     7681 acaataatgc tatccagtat tttaactagg ctgccttggt cgttaactag aagaagcata
     7741 gaaatatgat gttgctctat gattaaggtc ctagtcttaa aagaggctag gacaatatcg
     7801 gcctgctagc tgctgtcggc gtcttgttga ttgactagat tacaaaggct agaccaagta
     7861 gcaggcccag gccctttagt tgcaagggta ttagccccaa aaacaataat aaataacaat
     7921 tgtgtgaatc gaaaggaaaa ggagtttacg agaactcgag gtatgatact atgaaaatgt
     7981 cgtttcgctg gtatggaaag catgatccag taagtttaga ggaaatcaag gccattcctg
     8041 gtatgcaggg aattgtaaca gctgtgtatg atgtaccagt tggtcaggct tggccactag
     8101 aaaatatcct tgaattgaag aggatagttg aggctgcagg ccttgagatt tcagtcatcg
     8161 aatcaattcc tgttcacgag gacatcaagc aaggaaagcc caatcgtgat gagctgattg
     8221 aaaattataa gacctctatc atcaatgttg gtaaggcagg tattcctgtg gtttgctata
     8281 attttatgcc agtgtttgat tggactcgct cagatcttaa ttacccattg cctgatggat
     8341 caacctcact tgctttttta aaggcagact tggcagatgt ggatcctgtg gcagatgatt
     8401 tgaacctacc gggttgggat ttttcttact caaaagaaga gatgaaggct attattgagc
     8461 attatcgtca tcatatttcc gaagaagacc tgtgggctaa tttagattat tttattaagg
     8521 ctattatgcc aacagcagag gcagctggcg ttaagatggc tatccaccct gatgatcctc
     8581 cttatggtat ttttggctta ccacgtatca taacaggtca aaaggctgta gagcgcttct
     8641 tagaccttta tgattcccct aataatggga ttaccatgtg tgtgggctcc tatgcttctg
     8701 atcctcaaaa tgatgtgatc gctatgacgg agtacgcgct taagcgccag cgtattaact
     8761 ttatgcatac gcgtaatgtc actgctggtg attggggctt ccaagaaacc gctcacttgt
     8821 cacaggctgg tgacattgat atgaatgcta ttatcaaatt attggttgat tatgactggc
     8881 aaggaccact tcgtccagat catggtcgtc gtatctgggg agatcaaacc aaaacccctg
     8941 gctatgggct gtatgaccgg gcacttggtg cgacctattt taatgggctt tatgaggcta
     9001 atatgcgtgc agctggaaag ataccagatt ttggcattac tgtaaaaaca gttggagata
     9061 aatagaaaaa ggggcatgag atgagtcgag ttattgaatt taaggacaag gttgttgtga
     9121 tcacaggagc tggcggtgtc ctttgtggca gtatggcaaa ggcatttgca aaagcagggg
     9181 ctaaggtggc actgttagac cttaaccaag aggcggcaca ggcctttgtt gatgatattg
     9241 aggcagaggg tggtattgca aaggcctatc aggcaaatgt attgtctaaa gaaaacctag
     9301 aggccgttcg tcaggcagtt ttagcagatt ttggtccagc agatatttta gtgaatggcg
     9361 ctggcggaaa cagccctaag gcaacaaccg ataatgagtt tcacgacaca agcctgccag
     9421 aggatacaaa aaccttcttt gaccttgatg aagcaggtat cagctttgtc tttaatttaa
     9481 actatttagg caccttgttg ccgacgcaag tctttgctca ggatatggtt ggtcgtaagg
     9541 gggcaaatat tattaacatt tcttcaatga atgcctttac gccattaaca aagatcccag
     9601 cctattctgg ggctaaggca gccatttcca actttaccca gtggttggct gttcattttt
     9661 ctaaggttgg cattcgttgt aatgccattg ctcctggatt tttggtaacc aatcaaaacc
     9721 gtagcctcct tttcacagag gacggacagc caacggctcg tgctgaaaaa atccttaaga
     9781 atacaccaat gggacgcttt ggtgaggcag aagaattaat tggaggcctc tttttcttgg
     9841 ctgatgagca gtctgcttcc tttgtgaacg gcgttgttct gccaattgat ggcggatttg
     9901 cagcttattc aggcgtctaa gctaaaaaat aaaccacttg agaactcaaa ctgcaatgcc
     9961 tcaagtggtt tttctatcgt gacagcttgc tttgtagcca agctgccatt aataaaggta
    10021 tgatgatttg tggcttctat tgttccttat cactctagcc ttttttagca atcaacaagt
    10081 aatgatagct tttaaaaatg aaacgctgct tgattaggat ttatgattga cagcgttttc
    10141 ttactgtgtt agaattaatt catcagatga tttggaggtt ggaatgacag ctaaaactga
    10201 acaatttgtc ttttgtgtgg actcagatgg ctgcgcaatg gacaccatga cttataagca
    10261 tcagctcttt tttggtccgc ttgcggcgga ttattttgcg gtagcagacc aagcgtcttt
    10321 cttaaaagag tgggatcgca ttaatcttta ttcgcgtaca cgcggtgtta accgctttgt
    10381 tgggcttgtt atggggctag aatacgcagg agttacaggg attgacgctt taaagcaatg
    10441 ggtacaacac actgcctcat tatccaatca gtctctggag gcggagcttc ttaagcgtcc
    10501 tagtgatgac ctgcaaaagg ccttggactg gtcaaatgag gtaaaccgtc agattgaggc
    10561 ctacaaagga gaggcattgg catttctagg agctttagct gctcttaagg ccttgcacca
    10621 gcttggccag gtttttgttg tcagctcagc taataaagag gccgttcaaa aggaatggca
    10681 ggatcaaggc ctgatgacac atgttgatgg cttgtattgt caggatcgtg gcaaaaaaga
    10741 ggctgtcata gcacagctca ttgatgaagg atatgtgaga gagcgcatga tgatgatagg
    10801 agattcacca ggtgatctag cagctgctga gcaaaaccag atcacttttt ttccaatcct
    10861 cgttggtaag gaggctagct cgtggcagga tctgtcacat gctgctgaag cttttacaac
    10921 tggtgacttg acagagcttg atgtcaagag ccttacagaa gccttctggc gtaatcttga
    10981 taggtaggca ggtagctgac cagtggagct gagcctgtta gggcttggta gcaggttgct
    11041 gtagcgccat tcattaaaac agaaaagcaa gcagagaagg ctttagttga aaggaagtac
    11101 aatgacacat ttagtagatt taagaaaaaa accatatagc ctagacgaag aagctatttg
    11161 ctgggtggag gataccattg cagcaatgac cttggaggag aagataggtc agctatttgt
    11221 taatatgggg gctagtcgat cagaggatta tttaactcag gtgcttgagg attatcatat
    11281 tgcagctgtt cgctacaata aaggcatggc ttcagaaatt tgggatcaaa attatatttt
    11341 acaaaccaaa tccaagattc caatgctcat tgctgccaat acagaggctg gtggtgatgg
    11401 tgctgtcaat gatggcacta aggttggtga tgaaatcaag gtagctgcga caaacgatcc
    11461 taaatacgct tatgaaatgg gacggattgc aggactggaa gcgtcagctg ttggctgtaa
    11521 tgcctccttt gcgccaattg ttgatttgac gcgtaattgg cgtaatccaa tcattgctaa
    11581 tcgcaactgg ggggtaaatg ttgatcaaat cattgagctt tccaaagagt atatgaaggg
    11641 gattatggaa tatggtatca tgccctttgc caagcacttc cctggtgatg gtattgatga
    11701 gcgtgaccat catttgtcct ttgcctcaaa cccaatgacc aaggaggagt ggctatctag
    11761 ctttggacgt atttatggcg agcttgcaga ggctggctta cctggtatta tggcaggaca
    11821 tattcacctg ccaaatgttg aaaaggccat gcaccctgag cgtgagctag atgatatgct
    11881 tccagcctca cttaataaaa ccctcttaga tgagctgctg cgtggtgagc ttggctataa
    11941 tggtgctatt gtgactgacg cttcgcatat ggttgcgatg acagcctcaa tgccacgtcg
    12001 cttattgtta ccaacagcga ttgaggcagg ctgcgatctc tttttattct ttaatgaccc
    12061 agatgaagac ctacaatgga tgaaagaggg ctatgaggca ggaattttaa gtgacgaacg
    12121 ccttcatgac gcccttcgtc gtacgcttgg cttgaaagca aagcttggac ttcatcgctt
    12181 tgaaggacac cgagaagata ttatgctgcc taaggacaag gcgatggtct tgattaacac
    12241 accagaggct caagcaattg cagatgaggt tgccgacaag gccattaccc ttgtgaaaaa
    12301 caagcaggca gggattttcc cggtaactcc agagcgctac aagcgtgtgc tgattgttaa
    12361 cgtggagggc tataagggtg gctttggtgc tatgattgca ggacagaaga aacgggcctc
    12421 agacattgtc aaggaattgc tagaggcgcg tgggcatgag gtaactgtct gggaatcaac
    12481 cgaagagcga atcatgcagc taccagagga agagcgtgca gcggctattg ctaatgttta
    12541 tgcacaaaag cagccgattt caaacattac agagcattat gatttaattc ttaatttggt
    12601 ggacgtcaat tctggaggta cagttcagcg tattatctgg ccagctgcta agggaacacc
    12661 ggatcagcca ttctacgtcc atgaggtccc aacaatcgtt gtttcagttc agcatgcctt
    12721 tgcccttgct gatatgccac aggttggtac ttatattaat gcctacgatg gcaaggacaa
    12781 cactatgaag gctttggttg caaaattagc tggtgaatct gaattcactg gagtgtctcc
    12841 tgttgatgcc ttttgtggct tgattgatac ccagctatgg catagcttct gaggttgcta
    12901 caggataagt agaggcttta cgtgttctgc ggtgattgct ctgaatgatt taaaaagatt
    12961 tcaggataaa acctgttaat cagccccttg tagctgcaga aatagcccca taatccctgt
    13021 ggtggggagt tttatccgat atggagatga tagagcctgt taatcctaaa gaaaagctag
    13081 agggtcattc tagcttttct ttttgtgcct aatgctcaac cttgcttcag atgatagaca
    13141 agctataagc ttgttgataa gtgaaacaat tgaacagata atgtttttta gagatgatat
    13201 attaagaata attttaaatt atgaaaaaat ataatatatt aatgatttat aacaaaatca
    13261 ataataatag cttattttgt cag
//
LOCUS       DARYMD010000051        12932 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYMD010000051 DARYMD010000000
VERSION     DARYMD010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12932
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(24..1073)
                     /gene="citC"
                     /locus_tag="TU818_001563"
     CDS             complement(24..1073)
                     /gene="citC"
                     /locus_tag="TU818_001563"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEL0924362.1"
                     /translation="MTQHLIQHIFPFDKQQKAKIDRLLQRQHIRRDPHLDYTCAIIDE
                     QGEPIATGSLYGNSLRCLAVDQAYQGEGLLNHIVSHLIEEAYSRGHHHLFIYTKIAAA
                     PLLLSLGFHVIAMVDDTLCFLENKKRGFEHYLSQLEKPQISPQKTAAIVLNANPFTLG
                     HLHLIEKACADNELVHLFMVSQDSSLIPYHIRKELIIKGTAHLANIIYHDSGPYMISQ
                     ATFPAYFQKDELAVIDSQAKLDIVIFRHIAEKLQIKSRYVGEEPTSMVTQHYNTVMLK
                     QLPCYSIDVQVIPRKTFAEGKIISASLARQAIKDDDYALLELLLPKTSLDFFRSEAAQ
                     PTITKIKAATDLKHY"
     gene            1340..2403
                     /locus_tag="TU818_001564"
                     /pseudo
     CDS             1340..2403
                     /locus_tag="TU818_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
     gene            complement(2489..3373)
                     /gene="citG"
                     /locus_tag="TU818_001565"
     CDS             complement(2489..3373)
                     /gene="citG"
                     /locus_tag="TU818_001565"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEL0924363.1"
                     /translation="MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFL
                     TFVDSALALAPFFKIYLDIGFYHAKEDPGLIFERLRASGIEAEQAMFSATKGVNTHKG
                     VNFSLALLLGATGMYLADQPQLLDHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDL
                     KKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYL
                     MSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGG
                     TADLLVLSLYFAFLENQL"
     gene            complement(3366..4061)
                     /locus_tag="TU818_001566"
     CDS             complement(3366..4061)
                     /locus_tag="TU818_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0924364.1"
                     /translation="MNPIIEAVKNNLDLSRNIPLKIAFYNALKKTIILRQIPAGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIQDACEIFEIRKALET
                     LATSTAMYLMTEEDFQVMHDLLADCETFIEDDDLNRILDNFNSFNNLIYSYSQMVRLK
                     EIVTELQTYLVYFRKISISSLERRKRALSEHWMIYRGMKNRDHEQITLITHEHLNSSL
                     EFILQEMSRRQDD"
     gene            complement(4214..5617)
                     /locus_tag="TU818_001567"
     CDS             complement(4214..5617)
                     /locus_tag="TU818_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEL0924365.1"
                     /translation="MLLTVLAYAMIIIFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFTSDAKFVAFVGEDGLAKNLTAIGPMIMYGINNTAKTGIMLLFAILFFSIMLDAG
                     LFDPITEKMIRFAKGDPMKVLMATAIVAAAVSLNGDGTTTTLICCSAFLPIYKKLNMR
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLSVGPEILGYLAPGMVLSLLYVICWVAP
                     SMGRKERARLGVVDLTEEEMRKLTDITDPDTLSIRRPKNFAFNAILTIGLITWLVAGS
                     FYKAIAMAPLLLFAVGTCIALIVNYPVLKDQTKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALISAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYAIIIFII
                     FVVTIIAMGQMPLYIPQ"
     gene            5999..6343
                     /locus_tag="TU818_001568"
     CDS             5999..6343
                     /locus_tag="TU818_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924366.1"
                     /translation="MQFFQNMFRRSKKEAATSHQDRENKPEFPLDDWEPVPSYIAADK
                     KDYQTVSLIASAIAAGEQASSQFKVKRILQRNPEALTVSLIASSIAAGVYPESQFLVR
                     SIYSKKVNVSHK"
     gene            6361..6756
                     /locus_tag="TU818_001569"
     CDS             6361..6756
                     /locus_tag="TU818_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEL0924367.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPSQAPVVPPVQPAVAPAPVAE
                     KKAAEAPQAPAAPVSAGADAMPSPMPGIILKVLVNVGDVVHENQPLLILEAMKMENEI
                     VASTAGTVTGIHVTAGQVVNPGEGLITIS"
     gene            6806..7927
                     /locus_tag="TU818_001570"
     CDS             6806..7927
                     /locus_tag="TU818_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEL0924368.1"
                     /translation="METLIAGVTSITIPQIIMMLIGAVLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGTGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQLTKILFPIVITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQAELF
                     LNVQTLLIIIFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            8109..8417
                     /gene="citD"
                     /locus_tag="TU818_001571"
     CDS             8109..8417
                     /gene="citD"
                     /locus_tag="TU818_001571"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEL0924369.1"
                     /translation="MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNH
                     IRALIKTTLARLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
                     "
     gene            8405..9292
                     /gene="citE"
                     /locus_tag="TU818_001572"
     CDS             8405..9292
                     /gene="citE"
                     /locus_tag="TU818_001572"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEL0924370.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSNVETVVRVNSLDSCGALDIEAVVLAGVDVIRLPKTETAQDII
                     DVEAVIERVERDNGIAVGRTRMMAAIESAEGVLKAREIAKASNRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQAEVRHIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEISHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AQRVIALATAAGVLTEEDI"
     gene            9294..10826
                     /gene="citF"
                     /locus_tag="TU818_001573"
     CDS             9294..10826
                     /gene="citF"
                     /locus_tag="TU818_001573"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEL0924371.1"
                     /translation="MVKNKLGRDIPQEYADHYGVFEGELARITSYNESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLKDGMTISFHHHFREGDFVMNMVLDEIASMGIKDLAIAPSSI
                     ANVHEPLIEHIKNGVVTSITSSGLRDKVGAAISSGIMEKPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDEYGNVNGTIGKATCGSLGYAMIDAKYADQVVVLTDHLVDYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITQSPYFKNGFSF
                     QTGTGGASLAVTRFMREAMLQENIKASFALGGITNAMVELLEEGLVEKILDVQDFDYP
                     SAVSLGKNAQHYEIDANMYASPLSKGSVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEIGIAINP
                     NRPDLIEHFKDLKVPQFSIEELKEKAYSIVGTPDRIQYGDKVVALIEYRDGSLIDVVY
                     NV"
     gene            10819..11379
                     /gene="citX"
                     /locus_tag="TU818_001574"
     CDS             10819..11379
                     /gene="citX"
                     /locus_tag="TU818_001574"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEL0924372.1"
                     /translation="MSKELIFKGKAVTLADMLRAREDRSLRQGKLLTEFSNESLLSVT
                     MNIPGPIKTSPALLEVFDSVIKAILEKLSGNQISYQLRLLPKTGYEYYLVTALDSQAL
                     KLKMIELETDLPIGRLMDLDVLVLTNQLPTPISRTALGFPPRSCYLCSKEAKACSRNR
                     SHSVADMQTALVHLLQSFFDGGNQLS"
     gene            11410..12801
                     /locus_tag="TU818_001575"
     CDS             11410..12801
                     /locus_tag="TU818_001575"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEL0924373.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRTIRKVVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLETAVSATKEFGGHAQVAISYTTSPVHTIDYFVALA
                     KAYQAIGADSICIKDMAGVLTPETGYQLVKRIKESIALPLEVHTHATSGISEMTYLKV
                     VEAGADIIDTAISSFAGGTSQPATESMVIALEDLGIDTGVDMTRLTKIAEYFNTIRDH
                     YRAEGILNPKVKDTEPKTLLYQVPGGMLSNLLSQLKEQGLSDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNVISGERYKVVPNEIKDYVRGLYGQPPAPLGEGIKEKII
                     GDEAVITCRPADLIEPQLPLLRQEIAGYACCEEDVLSYASFPQQAKDFLGRREDPFYD
                     IPVQYVTVDIAMD"
BASE COUNT         3787 a         2581 c         2859 g         3705 t
ORIGIN      
        1 gttagagagg gggtagttgt tggttaataa tgcttaaggt ctgttgctgc tttgatctta
       61 gttatcgtgg gctgagcagc ctcgctccta aaaaagtcaa gtgaggtctt aggaaggagt
      121 agctctaaga gagcataatc atcgtccttg atggcctgtc tggcaagaga ggcgctgatg
      181 attttgcctt ctgcaaaggt ttttctaggg ataacctgca catcaatgct atagcaaggc
      241 agctgcttga gcatgacagt gttgtaatgc tgtgtgacca tgctagtagg ctcttcgcca
      301 acataacgac tcttgatttg gagtttttct gcaatgtgac ggaaaatgac aatatccaat
      361 ttagcttgac tatcaataac tgctagctca tctttttgaa aataagcagg aaaggttgcc
      421 tgactaatca tgtaaggtcc actatcgtgg tatatgatat ttgctaggtg tgcagttcct
      481 ttgatgatta attcctttcg gatatggtag gggatcaggc tactgtcttg actgaccata
      541 aagagatgaa cgagctcgtt gtcagcgcag gccttttcaa tcagatgcag atgaccaagg
      601 gtaaatggat tagcatttaa aacgattgct gcggtctttt gaggactgat ctggggcttt
      661 tctagctgtg acaggtagtg ctcaaagccc ctttttttat tttctaaaaa acaaagagta
      721 tcatcaacca ttgcaatgac atgaaagcca agacttagca atagaggggc agctgctatt
      781 ttagtgtaga taaacagatg atgatgccca cgtgagtagg cctcctcaat cagatgtgag
      841 acaatgtgat taagtaagcc ttctccttgg taggcttgat caacagctaa gcagcgcagg
      901 ctattgccgt acaaagagcc agtagcaata ggctcgcctt gctcgtcaat aatagcacag
      961 gtataatcta aatgagggtc tcttctaatg tgctgtcttt gtaacaaacg atcaattttt
     1021 gctttttgct gcttgtcaaa gggaaaaata tgctgtatca agtgctgcgt catatgctca
     1081 cctcttatta cgaaattatc ctcttgcctt tattatagca cgctataggg cttattctta
     1141 agcatcttag ctggtttatg aaaagaatgc acaaaaaaga catcaatgac ctattgtctc
     1201 tgatgtcatt atgatatgat taggactttt agataaatga ttaaggtatg gaggatttaa
     1261 gcctgcaaaa ggtggcaata ataattctga cttatgctat aatagagcta ttgatattaa
     1321 gggggataaa ggggctggta tgctttcgat tctaatgact ttatttgttg ggacgctggg
     1381 agggcttgtt gctaagcggc tgagtattcc tgcccctttt atgattggca gtatggtagc
     1441 tgttgcccta gcttctatcc tgacaaagca ggtagaggct attaacccca tgaagatttt
     1501 tgctcagatt attagtggtg cctatattgg ccaaagcgtc agcaaatctg acctgcttaa
     1561 tctgcccaag ctagccaagt ctattattag tctcatgtcc ttgttcacgc tgaatatgtt
     1621 tcttcttggt ggggtatttg tttactgctt tgatcttgat cctgtaacag ccttgttgag
     1681 ctgtttacct ggtggcatta tggacgtttc tcttatggca gttgatatgg gagcaaaggc
     1741 tgatatagtt gcgacattac agtcggctcg actggtcggt atgctcttgt ttcttcctgt
     1801 ttgggtgacg ttttgggtca atcgctttga cccaaaagca aaagctacta aaaaaaaaag
     1861 atagtcaaaa gcgctagctc ccaagataca agaccttcta ggaaagagca gctatggaat
     1921 aatgtccagg ttttaagcat tgctaccatt ggaggtttga tcggtttagg gctaaagata
     1981 cctgtaggcg ctctgattgt ttctttgctt ttttcaacag cactgaaggt gcttcggcaa
     2041 acaagtcaaa tgccaagtac acttcgttat atagcgcagg tttttgctgg ctctattatt
     2101 ggaacaagct ttactcagga tagtttgctt caaatgggac gtctgattgt tcctattctt
     2161 ttacttttga gtagctatct gatcatcaat ctcttttttg gctatatcat gtataaaaaa
     2221 ggtatcttgg atttgcaatc ggcactcttt gcctcatcgc ctgctggtgc gacagacatt
     2281 tcactattgg ctggtgagct tggcggagat atgcctaaaa tcgctggtat tcaaatcagt
     2341 cgaaccctct atactgttgt catcatgccc ttgttggtta aatggctcat tagtatatgg
     2401 taaacagaaa agcccctcag agcataaacc agagatacct agtcattacc aaataacata
     2461 tcaaggatct tgttcaggct tggagctgct ataattgatt ttctaaaaaa gcaaagtaga
     2521 ggcttagcac tagcagatca gcagtccctc caggactgag atgcttttgg atcagcttgt
     2581 cgttgtaggc tgacaaggca gcctttaagt cagcagtgct caaagagctg ttgtgcaata
     2641 gcagcatgtc ctgtttgact tgccgccaag ctttgatgcc tcctcggtga atcaggttgc
     2701 catcttccac aatagacatg aggtaaacca gcagttgcag ttgagcggtc tcctgatcag
     2761 tgctgcgaag gctcttgcgc aaaaaaggca gcgccttgtg agcaattgta ggatagccct
     2821 cgctggcttc tcctctaggg ccctttatac cgtaatctag aaagagcttc tcaccatagg
     2881 tgagctcttt ttttaggtct aagctaccaa aatcagtctc aaggagatga gctgttagag
     2941 gcttgacaag ctgacaaata gccagactat cctcctcagt aaaggctgtt acatggtcca
     3001 agagctgtgg ttgatcggca agatacattc ccgttgcccc aagcagaagt gctaaggaaa
     3061 aattgactcc cttatgggta ttgactccct tagttgcgct gaacatggct tgctcagcct
     3121 caatgcctga ggcacgcaag cgctcaaaga tcagaccagg atcttcctta gcatggtaaa
     3181 aaccaatgtc taaataaatc ttaaaaaagg gggctaaggc cagagcgcta tcaacaaagg
     3241 ttaagaagct catgtcatca tgagccccgt tatcaagctg atccacaagc ccaggcttag
     3301 gagataagga cacttcgtaa agtaaagcct ttagagcaag cctgctaata tcatcaaata
     3361 ccttcttagt catcctgacg cctgctcatt tcctgtagga taaattctag tgagctgttg
     3421 aggtgctcat gcgtaataag ggtgatttgc tcgtggtcac gatttttcat gccacgataa
     3481 atcatccaat gctcagataa agcgcgtttt cgtctttcta gggaagagat cgaaattttt
     3541 ctaaagtaaa caaggtaggt ctgcaattca gtgacaattt cttttaatct gaccatctga
     3601 ctatagctgt aaatcagatt attaaagctg ttgaaattat ctagaattct gttgagatcg
     3661 tcatcttcta taaaggtttc acaatcagcc aacaaatcat gcatgacctg aaaatcttcc
     3721 tctgtcatca aatacatagc ggtgcttgtt gccagtgttt caagcgcttt tctgatttca
     3781 aagatttcac aagcatcttg aatactaaca cccttgacaa taatgccttt tttaggaata
     3841 tgctctacca aatgctcctc tgataacaat cctagagcgt acctgattgg tgttctgcta
     3901 atatttaggg caatggaaaa ttctttttcg ttgatacgac tgccagcagg aatttgtctt
     3961 aaaataatag ttttctttag ggcgttataa aaagctattt tcaaagggat attgcgggat
     4021 aggtcaagat tattctttac tgcttcgata ataggattca tataatctcc ttaatgttca
     4081 tatcatgata ttattatact gaaaatcatt actaatgaaa ataataatta gcctcctaaa
     4141 aggcgaaagc catgctcgtg aaagaacatg gctttcatta gcccacacta cagtcctaat
     4201 aatagctcgt gacctattgt ggaatgtaaa gcggcatttg tcccattgca ataatggtta
     4261 caacaaagat aataaagata ataatcgcgt atttagcagc ttctttttgc cattctccca
     4321 tatcaagccc agtaagacga agaagcaggt aaataaaggc caccaatgga ctgagcaaat
     4381 ggaaggcttg tcccatcaga gaagcaagag ccatcgccat gttgctaaag ccatattcag
     4441 ctccagcctc cgctaagact ggcaaaatac catagtagaa gccatcattt gagataaaga
     4501 aagtaccagg agctgaaatc agggcaataa caagtcccca gaagccagcc aattgctttg
     4561 gaataatcgt tgcaaagctt tgagcaagag cactagccat accagagcct tggaaaagtc
     4621 ccatgaagat accagcagca aaaaccagaa taacaacctg aacagcatca ccggcattat
     4681 caccaatacg ctttgtttgg tcctttagga caggatagtt aacaataagg gcaatacagg
     4741 ttcccactgc aaataaaaga agtggtgcca tagcaatagc cttatagaaa gagccagcaa
     4801 ccagccaagt gattaagccg atggttaaga tagcattaaa ggcaaagttt ttaggacgac
     4861 ggatagaaag cgtatctgga tctgtaatgt ctgttagctt acgcatttcc tcttcggtca
     4921 aatcaacaac accaagtctt gcacgctcct tgcgtcccat gcttggcgca acccaacaaa
     4981 tgacataaag aagagacaaa accataccag gtgcaaggta tccaaggatt tcaggtccca
     5041 cactaagcac agacatggca cgcgcagttg gaccacccca aggaagcagg ttcatgatag
     5101 tgttttgcag gataatcaag acaccaagat tcatgatgcg catgtttaat ttcttataga
     5161 ttggtaaaaa agcagagcag caaatcaagg ttgttgttgt accatcacca ttaagtgaaa
     5221 cagctgctgc aacaattgca gttgccatca agaccttcat cgggtctccc ttagcaaagc
     5281 gaatcatttt ttcagtaatc gggtcaaaca agccagcatc tagcataatg gaaaagaaca
     5341 ggatcgcaaa aagcagcata atacctgtct tagcagtgtt attaataccg tacatgatca
     5401 taggaccaat agctgtcaga tttttagcaa gcccatcctc accaacaaag gcaacaaatt
     5461 tggcgtctga tgtaaaatca gcagagcctg ttaatataac agcaattgtc attatcaacg
     5521 gaatcatgac cagagctgta aaaggggtca tttttttctt catgacgaca tacatgaaga
     5581 taataatcat agcataagct agaactgtta ataacatatt gttatctcct ttttgatttt
     5641 atgacttcag tataaatgaa agcgttcgca aaagaaatac ctccatgtac ggaaaaacac
     5701 aaaaaaaaca ttttgaaagc agatcctgaa aaaataaatg gttacattaa tgtttttcaa
     5761 cagcagttag ttgctcttat cttcagtaat cgcagtgtgt ttcagcattt tttaaaatca
     5821 gtcatattta ttttagttaa ctgtttttat aaaaatggtt aactaaaata agaaaatcct
     5881 tgaaaatgtg aaagcgctct tagaaagaac acaaaaaagc cattccaaaa ggatgaggtg
     5941 gtatataata agcatagaag cttcccattt gtgggcaaac taagaaagga ggtagcttat
     6001 gcagtttttt caaaacatgt ttagacgctc taaaaaagag gcagccacaa gccatcaaga
     6061 cagagaaaat aagcctgaat ttccgttaga tgactgggag ccagtgccta gctacattgc
     6121 tgcagataaa aaggattatc agacagttag tctgattgcc agtgccattg cagctggcga
     6181 gcaagctagc agtcagttta aggtaaaacg aatcctacag cgcaatcctg aggccttaac
     6241 cgtatcctta atagcatcaa gcattgcagc tggtgtttat ccagagagtc aatttctggt
     6301 taggtccatt tatagtaaga aagtaaacgt tagccacaaa tagtaaaagg agaaaagatt
     6361 atgttgcgta agtttaaaat taccattgac ggaaaagagt acctagttga aatggaagaa
     6421 atcggtgctc cctcccaagc cccagtagta cctcctgttc aaccagcagt agctccagcc
     6481 cctgtagccg aaaaaaaggc agcagaagct ccgcaagctc cagcagcacc tgtatcagca
     6541 ggggcagatg caatgccctc acctatgcct ggtattatct taaaggtttt agttaatgtt
     6601 ggtgatgtcg tacatgaaaa tcagcctcta ttgattttag aggctatgaa aatggaaaat
     6661 gagattgtcg cctcaacagc tggtacagtc acagggattc atgttactgc aggtcaggtg
     6721 gtcaaccctg gtgaaggctt aatcaccatt agctaatcct aagtcgtgtc ttgatttaaa
     6781 atgttgtaga aaaggaagta catttgtgga aacattaatt gcaggagtaa cctccatcac
     6841 tattcctcaa atcattatga tgcttatcgg tgctgtctta atgtatctag gaataaaaaa
     6901 agaatacgaa ccaaccttac tagttcccat gggactgggt actattttag tcaactttcc
     6961 cggcacagga gtcttaacac aggttgttaa tggtgttgag caagaagggg tctttgatgc
     7021 cttattcaat tttggaatcg gtacagagct gtttccatta cttattttta tcggtattgg
     7081 tgccatgatt gactttggtc ctttacttca aaatcctttc atgctattat tcggtgcggc
     7141 agctcaattt gggattttct ttgttgtcgt tgtagccgta ttagctggct ttgatattaa
     7201 ggaagcagct tcaattggta tcattggtgc tgctgacggt ccaacatcaa tttttgtagc
     7261 aaaccaattg gcaaaggatt tgctagggcc tatcacagtg gcagcttatt cttacatggc
     7321 tttggttccg atcattcagc cctttgcgat caagctagtt actaccaaaa aagagcgtcg
     7381 tattcgtatg acctataagg ctgagaatgt gtcacaatta acgaagatcc tctttcctat
     7441 tgtgatcaca cttgtagccg gctttattgc tccaatttcg ttaccattgg ttggtttttt
     7501 gatgtttggg aacctgcttc gtgaatgtgg tgtcttggac cgattgtcac agaccgctca
     7561 aaacgaattg gtcaatatca tcagtatttt actaggacta accatctcta tcaaaatgca
     7621 ggccgagctt ttcttgaatg tgcaaaccct gcttattatc atttttggtc tgttggcctt
     7681 tatcatggat tcgattggtg gtgtgatgtt tgccaaattc ttgaatttat tccgtaagga
     7741 aaaaatcaac ccaatgatcg gagctgctgg aatttcagcc tttccaatgt caagtcgtgt
     7801 gattcaaaaa atggccactg atgaggatcc gcagaatttc atcttgatgt atgctgtggg
     7861 tgctaatgta tctggtcaaa tcgcctcagt tattgcaggt ggcttgctgc ttgcttactt
     7921 tagctaagaa aggacgtgct tatgacaatc aatatagacc atttgatcca atcctttgag
     7981 ctaatggcac ttggaatggc aggagtattt gttgtattag gaattctcta tattgtagca
     8041 gaggctctga ttaagctatt tccagtagaa aaataataga atatgatcta aacaaggagg
     8101 tcaatcaaat ggagatcaaa caaattgctg ttgctggttc gcttgaatct agcgacatga
     8161 tgataacaat atcacctaat gatggtcagg gaatcgtttt ggaattggat tcaagcgttg
     8221 aaaaacaatt tggcaatcat atcagagcat taatcaagac aacacttgcc aggctgggcg
     8281 ttgagtcagc aacgatcgaa gctgttgata agggagcctt ggattgtacc attcaggcaa
     8341 gaacaattgc agcagtccat cgtgctgctg gagttgagca ttacaactgg aaggagatcg
     8401 actcatggaa cgcttaagaa gaacgatgat gtttgttccg ggcgctaatg cggctatgct
     8461 aagagatgca cccttgtttg gagcggactc tatcatgttt gatttagagg attcagtttc
     8521 cttaaaagaa aaagacacct ctcgcgccct tgttcatttt gccctaaaaa cctttgatta
     8581 ttcaaatgtt gagacagttg tgcgcgttaa tagcctagac tcttgtggtg ctctggatat
     8641 tgaggcagtt gtgttagcag gtgttgatgt tattcgcctg ccaaagacag aaactgccca
     8701 ggatattatt gatgttgagg cagtcattga gcgtgttgag cgtgacaatg ggattgctgt
     8761 tggtcgtaca cgcatgatgg cagctatcga gtctgcagaa ggggtcttaa aagctcgtga
     8821 gattgcaaag gcctcaaatc gtctcattgg tattgccctc ggcgcagagg attatgtgac
     8881 taatatgaaa acacgtcgct acccagatgg acaagaatta ttctttgccc gcagcatgat
     8941 tcttcacgca gcacgtgctg ctgggattgc agcaattgat accgtttatt cagatgtcaa
     9001 caatacagaa ggcttccaag ctgaggtgcg tcatatcaag caattaggct ttgatggtaa
     9061 atctgtcatc aaccctcgtc agattccatt ggtaaatgag atttatacac caaccgaaaa
     9121 agagattagt cacgccaagc aagtgatctg ggccattcgt gaggctgaaa gtaagggatc
     9181 aggtgtcatt tcattaaatg gaaaaatggt agataagcca atcgtagagc gtgcacagcg
     9241 tgttatcgct ttggcaacag ctgctggggt attaacagag gaggacattt agcatggtta
     9301 aaaataaact tggtcgtgat attcctcagg agtatgctga tcactatgga gtatttgaag
     9361 gagagctagc acgtatcact agctacaatg aatcaagccg ccgcattaag cctgtaaagc
     9421 caggtgacag taaattgctt ggctctattc gtgaagctat tgaaaagaca ggcctaaaag
     9481 atggcatgac catttcattt caccatcatt ttcgtgaggg ggacttcgtc atgaatatgg
     9541 ttcttgatga gatagccagc atgggaatca aagatttagc tattgctcca agctctattg
     9601 ccaatgtgca tgagccatta attgagcaca ttaaaaacgg agtggttaca agcattacct
     9661 catcaggttt acgtgataag gttggggcag ctatttcatc agggattatg gaaaagcctg
     9721 ttgtgattcg ttctcatgga ggacgtgctc gtgcgattgc tagtggtgat attcatattg
     9781 acgttgcctt tttaggagca ccaagctcag atgaatatgg taatgtcaac ggtacgattg
     9841 gtaaggctac ctgcggctca cttggctatg ctatgatcga tgccaagtac gcagatcagg
     9901 tggtggtgct gacagatcac ctagttgatt atcctaacac cccaattagc attccgcaaa
     9961 ctgatgttga ttatgtcgtg acagttgatg ctattggtga tccacaagga atcgctaagg
    10021 gagcaacgcg gttcaccaaa aatcctaagg agctcctaat tgccgaatat gccgctaagg
    10081 ttatcacaca gtcgccttac tttaaaaatg gcttttcctt ccaaacaggt acaggaggag
    10141 cttccttagc agtgactagg ttcatgcgtg aggccatgct tcaagaaaat atcaaggcaa
    10201 gctttgccct tggaggcatt acaaacgcta tggtagaatt gctcgaagaa ggattagttg
    10261 agaaaatcct agatgtacag gattttgatt acccttcagc agtttcgctt ggtaaaaatg
    10321 ctcagcatta cgaaattgat gctaacatgt atgcctcacc actaagcaag ggatcggtta
    10381 tcaatcaatt agacacctgt attttatcag cgcttgaggt tgacactaat ttcaatgtta
    10441 atgtcatgac aggttctgac ggtgttattc gtggggcttc cggagggcat tgtgacacag
    10501 cctttgctgc caaaatgagt ctggtgattt caccccttat ccgcggacgc attccaacct
    10561 ttgtagatga ggtaaataca gtaattacac ctggaacaag cgttgatgtg gttgtcacag
    10621 aaataggtat tgctatcaat ccaaaccgtc cagatttgat agagcatttc aaggacttga
    10681 aggttcctca atttagtatc gaagaattaa aagaaaaggc ttactcgatt gttggaacac
    10741 ctgatcgtat ccaatacggt gataaggttg tagctcttat tgagtatcgt gatggcagcc
    10801 tgattgacgt tgtctacaat gtctaaggaa ttgattttca aggggaaagc tgttacccta
    10861 gctgatatgc taagggcacg cgaggacaga agccttcgtc aaggaaagct tttaacagaa
    10921 ttctcaaacg aaagcctgct ttctgtgacc atgaatattc caggccccat taaaacgtca
    10981 cctgctttac ttgaggtatt tgatagtgtt atcaaggcaa tcctagaaaa gctgtctggc
    11041 aatcagatca gctatcagct tcgtttgctg ccaaaaacgg gttatgaata ttaccttgtg
    11101 acagccttag atagtcaggc attaaagctc aaaatgattg agcttgagac tgatttaccg
    11161 attggcaggc taatggattt ggacgtttta gtgctgacaa atcagctgcc aacccctatc
    11221 agtcgaacag ccttaggctt tcctcctcgc agctgctatc tttgctcaaa agaggctaag
    11281 gcttgtagta gaaatcgcag tcactcggta gcagacatgc agacagccct tgtacactta
    11341 ctccaatcat tttttgacgg aggcaatcag ctcagttaga ctcaacggta ttcttataag
    11401 gagaatgata tgacaaaaat ccgtataaca gaaacagttt tgcgtgatgg tcagcaaagt
    11461 caaattgcta cccgcatgac tacaaaggaa atgattccga ttttagaaac actagataat
    11521 gctggctatc atgccctaga aatgtgggga ggagctacct ttgattcttg cctacgtttc
    11581 ttaaatgaag acccttggga gcgtctaaga accattcgta aagtagtcaa gaaaactaaa
    11641 ttacaaatgc tcctgcgtgg gcaaaatctt ttgggctatc gtaattatgc tgacgatgtc
    11701 gtccgcagct ttatccaaaa atcaattgaa aacggtattg atattgtgcg catttttgat
    11761 gccctaaatg atccacgtaa tctagagaca gctgtttcag caacaaaaga attcggtggc
    11821 catgcacagg ttgctatttc ttacacaaca agtccagttc atactatcga ttattttgta
    11881 gccttagcaa aagcctatca ggctattggt gcagattcga tttgtatcaa ggatatggct
    11941 ggtgtgttaa ccccggagac cggttatcaa ttagtgaagc gtatcaagga aagcattgct
    12001 ctaccacttg aggttcacac gcatgctacc agtggtattt ctgaaatgac ctatctcaag
    12061 gtcgtagagg ctggtgcaga tattattgat actgccatat cctcatttgc cggcgggaca
    12121 agccagccag caacagaatc gatggttatt gctttagagg acttggggat tgataccgga
    12181 gtagacatga caaggctgac aaaaattgcc gagtatttta atactatccg agatcactac
    12241 agggcagagg gcattttaaa tcccaaggtt aaagacactg agcctaagac cttgctttat
    12301 caggttcctg gcggcatgct gtccaatttg ctaagtcagc ttaaggaaca gggactctct
    12361 gacaaatatg aagaggttct ggctgaggtt ccaaaggtta gagctgattt aggctacccc
    12421 ccactggtga ctccgctatc gcaaatggtt ggcacacagg ccttaatgaa tgttatttca
    12481 ggtgaacgct acaaggttgt cccaaacgaa atcaaagact atgtcagagg actttatggc
    12541 caacctcctg cgccactagg tgaaggtatt aaagagaaaa tcattggtga tgaagctgtt
    12601 atcacttgtc gtccagcaga tttgattgag ccacaattgc ccttgcttcg tcaagaaatt
    12661 gcaggctatg cctgctgtga ggaggatgtg ctgagctatg cctctttccc tcagcaggca
    12721 aaggatttcc taggacgcag agaggatccc ttttatgata tcccagttca gtacgtcacc
    12781 gttgatatag caatggatta atcaaaagaa taaaaagcaa gataactaat aaaatcaatc
    12841 tcctaattat tagtcaaagc tacctaccaa taaactcctt aatcagaacc acccgtctaa
    12901 tgaggtgccc ccaaaaggtt agtccaaaac tt
//
LOCUS       DARYMD010000052        12651 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYMD010000052 DARYMD010000000
VERSION     DARYMD010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12651
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            4..579
                     /locus_tag="TU818_001576"
     CDS             4..579
                     /locus_tag="TU818_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL0924374.1"
                     /translation="MKKVINTILLAACFLFFLGNFTTNVLAEGINDKIENGTESDISF
                     QNGELLKNYLILEGERVYFDYDRATQDKVSDDVLEMGMLVEAISKDYSEKTFTPDKYF
                     KASWPIHGNYCGPGHNGNNFTLPVVDVLDQGCQNHDSCYKWGAGIGANCECNRQLVNY
                     IKVYRRWMPANVLGVADAIRVYFETVGSIGC"
     gene            928..1110
                     /locus_tag="TU818_001577"
     CDS             928..1110
                     /locus_tag="TU818_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL0924375.1"
                     /translation="MLTYDEFKQAVDNGYITGDTVTIVRKNGQILDYVLPHEEVRNGE
                     VVTDEKVEEVMRELDK"
     gene            1308..1697
                     /locus_tag="TU818_001578"
     CDS             1308..1697
                     /locus_tag="TU818_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL0924376.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            1694..2905
                     /locus_tag="TU818_001579"
     CDS             1694..2905
                     /locus_tag="TU818_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL0924377.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYIPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            2918..4264
                     /gene="asnS"
                     /locus_tag="TU818_001580"
     CDS             2918..4264
                     /gene="asnS"
                     /locus_tag="TU818_001580"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL0924378.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKRYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            4564..5658
                     /locus_tag="TU818_001581"
     CDS             4564..5658
                     /locus_tag="TU818_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0924379.1"
                     /translation="MMNRKKHTKLIRHYSICSAVAVLAAVSLGTGQDVQASEPNPYPD
                     VRRFLDEKYDGDVDKLSKQLQGYFGSLREYIEFELKNGKQGPAGPQGPKGDKGDSGEP
                     GPQGPVGPAGPKGDRGLDGRRGPAGQQGEVGPVGPQGPQGEQGPKGDRGEQGPKGERG
                     EQGPKGERGEQGPKGDRGEQGPKGERGEQGPKGERGEQGPKGDRGEQGPKGERGEQGP
                     KGDRGEQGPKGERGEQGPKGDRGEQGPKGDRGEQGPKGDRGEQGPKGDRGEQGPKGER
                     GEQGPKGDRGEQGPKKEPEKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSAPKASLP
                     STGDTSQSFVAAALGFIASAGLLVFKRKKN"
     gene            6184..7074
                     /gene="rapZ"
                     /locus_tag="TU818_001582"
     CDS             6184..7074
                     /gene="rapZ"
                     /locus_tag="TU818_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL0924380.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            7071..8048
                     /locus_tag="TU818_001583"
     CDS             7071..8048
                     /locus_tag="TU818_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL0924381.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            8045..8956
                     /gene="whiA"
                     /locus_tag="TU818_001584"
     CDS             8045..8956
                     /gene="whiA"
                     /locus_tag="TU818_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL0924382.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIRYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            9316..10713
                     /locus_tag="TU818_001585"
     CDS             9316..10713
                     /locus_tag="TU818_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL0924383.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVLRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGLDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HEADLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            10953..12503
                     /locus_tag="TU818_001586"
     CDS             10953..12503
                     /locus_tag="TU818_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL0924384.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVTVIKGTGDMLLVAGSGHSHEHDHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKSAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGNWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGENKTFTYKYVGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
BASE COUNT         3730 a         2521 c         3006 g         3394 t
ORIGIN      
        1 tttatgaaaa aagtaataaa tactattcta ttagctgctt gttttttatt ctttttaggt
       61 aattttacta caaatgtatt agctgaaggg ataaatgata aaatagaaaa tggcactgaa
      121 agcgatatta gcttccaaaa tggtgaactc ctaaaaaatt atcttatcct agaaggtgaa
      181 cgagtatact ttgattatga tagagcaact caagataaag tatcagatga tgttctagag
      241 atgggaatgt tagttgaagc tataagtaag gattattctg agaagacatt caccccagat
      301 aaatatttta aagctagttg gcctatccat ggtaactatt gtggaccagg tcataatggg
      361 aataacttta cgttgccagt agtagatgtt ttggatcaag gttgccaaaa ccacgatagt
      421 tgctataagt ggggtgccgg tattggtgct aattgtgaat gtaaccgtca gctcgttaat
      481 tacataaaag tttatagacg atggatgcca gcgaatgtcc ttggcgtagc cgatgctatt
      541 agagtatatt ttgagacagt aggttctata ggatgttaaa tttcaaaaaa aacgttagtg
      601 attattcgaa gtactatatt ttgagtatag tgttattatg gataggaatg ttctttgttc
      661 cttgggataa gactctattc ggtgtttcga tttatctgtt tgttatgcaa aagttattta
      721 tagtgtttgg tttgacggct atcttcatgg cctttgtgtc taaaaaaata aatctattta
      781 tttggggaat attatttatt ttcgcatttt ggattaatat gtttttgtta ttttccgtat
      841 taccaatttt ggggaattag tttaacaaaa aagaagaggg ggggttctcc ctcttctttt
      901 acgaataaat agataaggag gtgctttatg ctaacatacg acgaatttaa gcaggcagtt
      961 gataacggtt atatcacagg cgacacagtc acgatcgtgc gtaaaaacgg acagattttg
     1021 gattatgtgt tgccgcatga ggaagtaagg aacggggagg ttgtgacaga cgaaaaagtg
     1081 gaagaggtga tgagagaatt agacaaataa aaaagacctc gtccagaagt cggggaattg
     1141 tcggggacaa cgtttgtaaa tgtttctatt ccaacataaa acattttttg atataatagg
     1201 aaggatcata tgcaaaggag ctgaaattgg acaagcacaa aaggctcaaa acagttttat
     1261 atcaatgtgc cagcttggtc gtactgcttt gtcttggagt gatgagcatg ttttatcttg
     1321 ctgttcatga tcaatttgac aagaaatcaa ggttagccga gatagcaaaa tcaagagctg
     1381 gtgtcatctc aattgatcat attgattgct atcatggcac tcagagctac ctcagtcttt
     1441 ttggaaaaaa caaggcaggc aataccatca tcgtcacaat agaggagcaa tcagagcagc
     1501 tcttgcttag tcgccctagc aatggcatta gtgctaagga agcacaggaa attgcctacc
     1561 atgccggagc aaggactatt gaagcagtga catttgggat tgaaaaccac aagaggattt
     1621 gggaggtggc tgctcaaaac ggctactatc tgattgattt caaaaccgca aaagtgatca
     1681 aaaaggaggt tttatgacca agctatcaag gcgcgtgtta gcaatggaag aaagcgtcac
     1741 cctagcagca ggtgctagag caaaggcact aaaggctcag ggacgcgata ttttaagcct
     1801 aactctggga gagccagatt ttataacacc gcagcatatc caagaaaagg ccattgaggc
     1861 catcaccact ggtaaggcaa gcttttacac tgttgcttcg gggttgccag agctcaagga
     1921 cgccattgct gattacatgg cacgatccta tggttatatt cctaccagac aggagattgt
     1981 agtggggaca ggcgccaaat acgttttgta tgcctttttc atggctgttt taaatcctgg
     2041 tgatcaggtg ttgattccga ctccttattg ggtttcttat gctgatcaga ttaaaatggt
     2101 agacggggta ccggtctttg tacagggctt ggaggaaaat caatttaagg tcacagtaga
     2161 gcagctagag gctgccagaa ctgatcaaac aaaggttgtt ttgatcaatt ctccgtccaa
     2221 tccaactggc atgatttaca gccgacagga gcttgaagcc attggcaatt gggctgttca
     2281 gcatgatatt ctgatcctgg cagatgatat ctatggtgca ttggtctaca atggcaatca
     2341 atttactcca atatcagcct tatcagaggc tattcgtaga cagaccatta ctgtaaatgg
     2401 cgttgccaag agctatgcga tgacaggctg gcgtttgggc tttgcggtcg gagacactga
     2461 tattatcgct gctatgggta agattatcgg gcaaaccacc tctaatgtga caacagcgtc
     2521 ccaatatgca gcgattgagg cctttggcgg tgaccaaacg tcagttgagg agatgagaca
     2581 ggcctttgaa gagcgcctca ataccattta tcccctgctc aatcaagttc ctggctttga
     2641 ggctattaag ccccaaggag ccttttattt ctttcccaat gtcaaaaaag ctatggagat
     2701 gaagggcttt accgatgtga cagcctttac tgatgcgatc ctagaagagg taggactggc
     2761 tgttgtcagc ggagctggct ttggtgctcc agaaaatatc aggctaagct atgccactga
     2821 tttggcaacc ctaaaagaag ctatcagacg actcaatcag ttcatgacaa ctgacagcag
     2881 ccatgacaac aaagagaatg aatagaaaag agacattatg accaaaaaat acgtttccat
     2941 tatcgatgtt aaagaccatg taggacaaga agtgacagtt ggtgcttggg tcgccaacaa
     3001 gtcaggcaaa gggaaaatag cctttttgca attgcgtgat ggctcagcct ttttccaggc
     3061 agttgccttt aagccaaacc tgatccaagc ctttggtgag gaagcaggag cagctaagtt
     3121 tgacacgatt aggcatctca gccaagaaac ctctgtctta gtaaagggca ttgtcaaaga
     3181 ggacgctaga tcaaaatttg gctatgagct agacattacg gacctagagg ttattgggga
     3241 ttccaaggat tatccaatta ctccaaagga gcatgggaca gactttctca tggatcaccg
     3301 tcacctttgg ctgcgctctc gcaggcaggc agcaatcatg caaatccgta atgccatcat
     3361 ctatgcttcc tatgagtttt ttgatcaaaa tggctttatc aagtttgata gcccgatttt
     3421 atcaggcaat gctgctgaga acacaacaga gctatttgag acagattatt ttggcaatcc
     3481 agcctttctc agccaatcag gtcagctata ccttgaagct ggtatgatgg cgcttggtcg
     3541 cgtctttgac tttggtccgg tatttcgtgc cgaaaaatca aaaacgcgcc gccatctgac
     3601 agagttttgg atgatggacg cagaataccc cttcttatcc catgaggaat ccttagacct
     3661 acaggaagcc tatgttaagg cgatgattca gggtgtgctt gatcgtgctc cacaggcatt
     3721 ggagcttcta gagcgtgaca cagagctgct gaaaagatac attgcagagc ccttcaagcg
     3781 tgtctcctac gacgatgcga tcagcctgct tcaggagcac agcacagatg acgatgccga
     3841 ctatgagcca attcagcatg gcgatgactt tggctcaccg catgaaacct ggatttccaa
     3901 ttattttggg gtcccaacct ttgtcatcaa ctacccagct agctttaagg ccttttacat
     3961 gaagccggtt cccggcaatg aagagcgcgt gctatgtgcg gacctgctag caccagaggg
     4021 ctacggtgag attatcggag gctcggttcg tgaggataac tatgacaaat tgttggcgaa
     4081 aatcaaggct gaaggcctaa atcctgagga ttatgacttt taccttgacc ttcgcaaata
     4141 tggctcagtg ccgcatgctg gttttggact tggactagag cgcatggtga cctttgttgc
     4201 aggtaccaag cacattcgtg aggctattcc atttccacgc atgcttcatc gcttaaaacc
     4261 ataatgaacc ctatcagcgt ccgccattgg gcgctttttt gctgcgctga gcagtactta
     4321 gagctcaagc ctcccagtta gacttggcag agctgtggct ctttgcttga gctattgtag
     4381 gcaaaggtat cactggatct gaaaacaaca aaatcagaca agtgatatca aaattaaaaa
     4441 aaaaaaaaac gaaacctagg aggatcggtg agcttattag tttggcacta atcatcatta
     4501 tgctataatt gtcttcacaa ataatttaga aatagctcat atttctatca ttaaaggaga
     4561 gagatgatga atcgtaaaaa gcataccaaa ctcattcgtc actacagtat ctgctcagca
     4621 gtggctgtcc tagcagcagt tagcttggga acaggtcagg acgtacaggc ttcggaaccc
     4681 aatccatatc cagatgtgag gcgtttcctt gatgagaagt acgatggaga tgtggataaa
     4741 ttatctaaac aacttcaagg ttattttggt agtttaagag agtatataga gtttgaactt
     4801 aaaaatggca aacaaggtcc tgctggccct caaggcccaa agggtgataa aggagactcc
     4861 ggagagccag gtcctcaagg tccagtgggc cccgctggtc caaagggtga tcgtggttta
     4921 gacggacgac gtggcccagc aggtcagcaa ggggaagtcg gcccagttgg tcctcagggt
     4981 cctcaaggcg agcaagggcc aaaaggcgac cgtggcgaac aaggaccaaa gggtgaacgc
     5041 ggtgagcaag gaccaaaggg tgaacgcggt gagcaagggc caaaaggcga ccgtggcgaa
     5101 caaggaccaa agggtgaacg cggtgagcaa ggaccaaagg gtgaacgcgg tgagcaaggg
     5161 ccaaaaggcg atcgtggcga gcaaggacca aagggtgaac gcggtgagca agggccaaaa
     5221 ggcgatcgtg gcgagcaagg accaaagggt gaacgcggtg agcaagggcc aaaaggcgat
     5281 cgtggcgagc aaggaccaaa gggtgatcgt ggcgagcaag gaccaaaagg tgatcgtggc
     5341 gaacaaggac caaagggtga tcgtggcgag caaggaccaa aaggtgaacg cggtgagcaa
     5401 ggaccaaaag gcgatcgtgg cgagcaaggt ccaaagaagg agccagaaaa agacaccaag
     5461 ccatcagtgc caaaggcacc agataatatg gctgcaccaa aggctccgga gaagaagaac
     5521 cctaaagcac cggctcctaa gtcagctcca aaggcatcat tgccatcaac aggagacact
     5581 agccaatcat ttgttgcagc agcccttggc tttatcgcta gcgcgggctt gctagtcttc
     5641 aaaagaaaga aaaactaagc tagctaaaga ctgtaaacaa gcctcaactg ttacagcaag
     5701 cctctttgac atcttgcaga taagaggatt tcttagcgaa tgaagtgtgt ctaaagtcag
     5761 atactctgct ggactagcag tagctgatct ccctgaaaat cagttatgct aaagcattga
     5821 gccttagttg caaggcttag gtgtgacctt ccaaaggaag ctgcttttgc ctgtatcact
     5881 ttaggaagat atctaaaaga gacacttttt tcacgctgaa gctaagctag cttttcctat
     5941 gacaaatatc ctataacaat aaactccaaa caaaagagag gtcaaatggt acctctcttt
     6001 tacttagctt taggattgat agattctaaa ggcttccttg tttcttgatc aagaagtcct
     6061 tactgataga gtctgtctta gccgggctta tatggtataa tacctaatgg agataagaaa
     6121 agtccttaac aaatagagtt tcatctattg ttacaggagc aaccaagtga aaggagatgc
     6181 tacatgtcag ataaacaaat caatttggtt attgttacag gaatgagtgg cgccggcaaa
     6241 acagttgcca ttcaatcatt tgaggatttg gggtatttta ctgttgataa catgccacca
     6301 gctttagtgc ctaaattttt agagctgctt gagaggacca atgaaaccca aaaggttgct
     6361 ctggtagtgg atatgcgcag cagacgcttt ttcaaggaga ttaactctat cttagatcat
     6421 attgagctaa atgccaacct caagctacgg atcctctttc ttgatgcgac tgatagtgag
     6481 ctagtgtcac gctataagga aactagaaga agtcaccctc tggctgctga tggtcgggtg
     6541 cttgatggga ttcgacgaga aagagagctg ttagtcccgc ttaagagcat gagtcagcat
     6601 gtggtcaata ccaccgatct aaccccaaga cagctgcgta aggtgatttc ggatcagttt
     6661 tcaagcgagt cagaccaagc ctcatttaga attgaggtga tgagctttgg ctttaaatat
     6721 ggcctcccct tagatgcgga ccttgtcttt gatgtgcgct ttttgcctaa tccttattat
     6781 caggtggcgc taagagagca gacagggctt gatcaggctg tttttgatta tgtgatgact
     6841 catcaagagt cagaggcctt ttataatcat ttgttaggct tgattgttcc tattttgcct
     6901 gcttatcaaa aggaaggcaa atcagtgcta accattgcta ttggctgtac aggtggtcag
     6961 catagaagcg tcgcctttgc ccatcgcttg gcccaagact tgacagcaga ctggccgctg
     7021 catgagagtc atcgggacat caatcgtcgt aaggaaacgg taaatcgctc atgagaaatc
     7081 ctaaaataac ggtgatagga ggaggaacag gtattcctgt tatcctaaaa agccttcgca
     7141 aggaggcggt tgacattact gcggtggtca ctgttgctga tgatggtggg tcatctggta
     7201 agctgcgcaa tgccatgcag cttaccccgc caggtgattt gcgcaacgtc ttgttggcca
     7261 tgagtgacat gcctaagttt tatgagcgtg tgtttcagta tcgttttaat gaggcagatg
     7321 gtgctctagc tggtcatcct ctaggcaatt taattatcgc aggtatttct gagatgcagg
     7381 gatccaccta taacgctatt cagattttga cgaaattttt ccatatcacc ggcaagattt
     7441 ttccctcaag cgagcagccc ttgacactgc atgctgtctt taaggacggt catgaggtgt
     7501 caggagaaag ctctattgcc agctaccaag gcatgattga ccatgtctat gtgaccaata
     7561 cctacaatga tgacctgcca aaggccagtc gtaaggtggt tgaggccatt ctccaaagtg
     7621 atatgattgt gcttggtcct ggttccttgt ttacctctat tttgcccaat cttgtaattc
     7681 cagagatcaa agaagccctg agagtaacca aggcagaggt ggtttatatt tgtaacatta
     7741 tgacccagta cggtgagaca gagcaatttt ccgatgcgga tcatgttgcg gttttaaatc
     7801 agcatctggg cagggactta attgacactg ttttggttaa tgttgagcag gtgccaaaaa
     7861 gctatatgaa ttccaaccaa tttgacgaat atctggtcca agtagagcat gactttgcag
     7921 gtctgtgtaa gaccgcaaag cgtatcatct cgtctaattt tctgcgtttg gagaatggcg
     7981 gagcctttca tgacgggcac ttggttgtag aagaattaat gaacctagtt aggataacca
     8041 agctatgagt tttacgacaa ctgttaaaga agaattgatt catttatctg cttctgatca
     8101 aacagaatta tcagcaatca tcaagctggc tggtagccta ggcttggcta atcagagctt
     8161 gaatttgtct atcacaactg aaaacgctaa gattgctcgc tacatctatg cgcttatcga
     8221 agacacctat catatcattc cagaaatcag gtaccatcaa aagaccaact tgaaaaaaaa
     8281 tcgtgtctat acggtttatt tggataagca ggtggataag ctcttagcag atttaaagct
     8341 ggcagattct ttttttggca ttgagacagg tattgagcag caggtcatgt cagatgatga
     8401 tgctggtcgg gcctatctca agggtgcttt tttagcggca gggactgtaa gggatccaga
     8461 atccggcaag tatcagctag agatctactc tgtctatcta gaccatgctc aggatttggc
     8521 ccagctcatg cacaaattca tgctagatgc caaggttatc gagagaaaaa atggtgcagt
     8581 aacctatttg caaaaggctg aggacatcat ggattttctc attattattg gtgccatgtc
     8641 gtgtaaggag gagtttgagg ctgttaagct tttgcgtgag gcgagaaatg acatcaatcg
     8701 ggccaataat gcagagactg ctaatattgc taaaaccatc accgccagca tgagaaccat
     8761 taataatatt atcaaaatca tggatacgat tggcttagac agcctgccag ttgagctgca
     8821 gcagattgcc cagatgagag tagccaaccc agactattct cttcaacaaa tcgcagattc
     8881 gcttgacttt gccatcacta agagtggggt caaccatcgc ctgcgaaaaa tcaataagct
     8941 ggcagaggat ttataaagac agcttagcct ttttcaggct gataaaaaag ggggtaaggt
     9001 gatacgaaca agccgccttt taaggcatgc cttgttgagc tttctctagg ctgttgatgg
     9061 agtgatctca aggcgctttt gttactgtca ttccaacagg ctatctgatt ttgggatgac
     9121 ttcttactaa taagcttttc taatggctgg ctgacaacga ttagcgatat agttaaggct
     9181 tatcgtgatt caacaagagg ctttagtctc ttttttgctt gtcagaatta tttttttagg
     9241 cttttcttac aaatgagagg acaatgtgac aatctgtggt atgatattag taatgaatac
     9301 aaaggagaac aaatcatgtc atgcacaact attcttgtcg gtaaaaaagc gacctatgat
     9361 ggatcaacaa tcgttgctcg tacagaggat tcacaaaatg gggaatttac ccctaaaaaa
     9421 atgacagttg ttagaccaaa agaccaacct agacactatc aatctgtctt gtctagcttt
     9481 agcatggagc tgccggatca gccgatggct tatacctcgg tgcctgatgc cctaggaaag
     9541 gacggtatct ggggagaagc aggtgtcaat accctcaatg ttgctatgtc agcaactgag
     9601 accattactt caaatgctcg cgttcttgga gcagatcctc ttgtttcctc tggtattgga
     9661 gaagaggaca tgctgacctt ggtgcttcct tatattcggt ctgcaagaga gggtgttctt
     9721 cgtttgggag ctatcctaga agcatacggt acctatgagg ctaacggtgt tgccttttct
     9781 gatgagcatg agatttggtg gctggaaaca ataggtggtc atcattggat tgcaaggcgc
     9841 gttcctgatg atgcttatgt cactaatccc aaccagtttg gccttgatca ctttgaattt
     9901 aacaatccag aggaatacct gtgttccaag gatttaaagg actttattgc caaatatcat
     9961 ctagatttga cctatagcaa cgagcatttt aaccctcgct acgcctttgg tagccaaaga
    10021 gataaggatc gccattacaa tacaccacgc gcttggatta tgcagcaata ctttaatccg
    10081 gagtttctgc aggatccgcg cagctttgaa cttccttggt gccaaagacc tgatcgcaag
    10141 gtgaccattg aagacgttaa gtacgtgctt agcaatcatt atcaggacac cccttatgat
    10201 ccttacggcc cagagggaac gccgactagt cgaaaatcct ttaggccgat tggtattaac
    10261 cgtacgagtc aaactgctat tttacatatc cgtcccaaca agcctaagga aattgctgcc
    10321 attcagtgga tggcctatgg ttcgatgccc tttaatacaa tcgttccgct attcacccag
    10381 gtcaagacca ttccagatta ttttgcaaac actgttgaaa atgtttccac agacaatttc
    10441 tattggacca atcgcttgat tgcagccctg gctgatcctc acttcaagca ccatgaagca
    10501 gatttggagg actatctcga aaaaacaatg gccaagggtc atgccatgct gcatgctgtt
    10561 gaagcagcgc tagtaaaagg tcagccggtt gacctagaag aggccaacca aggcatgagt
    10621 gatgacattc aggcagatac acaggctctg ctcaataaga tcctctttga tgctagcaat
    10681 ctcatgacca accgctttag cctaagcgac taagtaatct caatagtcaa acgagctcat
    10741 atcattatag atatgggctc ttagcttgaa aaggatagta gagcggtctt atagtcagac
    10801 taattaatgg taacgatgag tccagttaag gtaaaaaaag agcacttagc taatgcaaaa
    10861 aaagtaaaaa acttgcaaaa gaatgatatt gtgttatact taaccagtaa atattaagag
    10921 ctatttgcga tatgatatat agaggaggaa tcatgaaaaa gaagtatctt ttaatgatga
    10981 gtgtgctcgg tgtctttttt gcgggacaga tcagtcaagc aaaacaggtc ctagcagata
    11041 gtaaggtcaa aattgttacc accttctatc ctgtttatga atttaccaaa ggcgttgtcg
    11101 gaggtgaggg aaatgtgtct atgctgatga aagcaggaac agagcctcat gattttgagc
    11161 cgtcaacaaa ggacatcaaa aagatccaag atgccgatgc ctttgtttat atggacgata
    11221 atatggaaac ttgggtccct gatatgaaga aatcactgac ttctaagaag gttacggtga
    11281 ttaagggaac aggagatatg ctattggtag ctggctctgg tcacagccac gagcatgacc
    11341 atgacgatgc cgataaaaag catgatcatg accacgacga ggaaggacac agccatgctt
    11401 ttgacccgca cgtatggttg tcaccttatc gcagcatcac cgttgtcgaa acaattcgtg
    11461 atggtctatc taaggcctat cctgacaagg ctgaccactt caaatctaat gccgctgctt
    11521 atattgaaaa gctcaaggaa ttagataagg agtatagtga cgctttttca gctgccaagc
    11581 aaaagagctt tgtgactcag cacgcagcct ttggttatat ggcgcttgat tatggcttga
    11641 accaaatctc aatcaatggt gtcacaccag atacggagcc ttcagctaag cgcattgcag
    11701 agctatcaaa atacgtcaaa aaatatgaca ttaactacat ttattttgaa gaaaatgctt
    11761 caagcaaggt tgccaaaacc ctagccaagg aggctggtgt caaatcagct gtccttagtc
    11821 cgcttgaagg cctaactgaa aaggacatga aggccggcaa ggattacttt accgttatgc
    11881 gtgaaaacct caaaacccta cgcttaacaa ctgatgtaga aggaaaagaa attcttccag
    11941 aagaggatac cactaaaact gtttataatg gctactttaa ggataagcag gtcaaagacc
    12001 gcaaattgtc tgattggtct ggtaactggc agtctgttta cccattcctt caagacggta
    12061 cattagatca ggtatgggac tataaggcta aaaaatctaa aggaaaaatg accgcagctg
    12121 aatacaagga ttattacacc actggctatc agacagatgt cagtcatatc aagattaatg
    12181 gtaagaaaaa taccatgacc tttgttcgta atggtgaaaa taaaaccttt acttataagt
    12241 acgtcggtaa aaagattttg acctatccaa agggcaatcg tggcgtgcgc ttcatgtttg
    12301 aagctaagga gccagacgct ggtgaattta aatatgttca gttcagtgac catgctatcg
    12361 caccaggtaa ggcggagcat ttccacctat actggggtgg tgacagccaa gaaaagcttc
    12421 acaaagagct agagcattgg ccaacttact atgatgcgga cctatcaggt cgtgccgttg
    12481 cccaagaaat caatgctcat taaccactca aaagactagg cagttcaatc ggcctagttt
    12541 tttcttgtct tagttgctgt ataggaccta aatgctgata gctggtctta agatttattt
    12601 ttaatttttc taactatatt taggttgtat ttgtttgtta ataccaaatc c
//
LOCUS       DARYMD010000053        12359 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYMD010000053 DARYMD010000000
VERSION     DARYMD010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12359
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(44..2632)
                     /gene="hylB"
                     /locus_tag="TU818_001587"
     CDS             complement(44..2632)
                     /gene="hylB"
                     /locus_tag="TU818_001587"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL0924385.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     AQGKTLLEVLDQEGQRVATVPVEILAAEAPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVTKNLADLTKDQKSTYLWSDLADLHQSSHMTATCRRLEEMAKQVSSLASR
                     YYQDKELIRLIKDKLAWLTLNYYHPQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRLTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYTLFINGQETALTEEILYRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQTHSQASDSYAYTLLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQGLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
     gene            complement(2578..3231)
                     /locus_tag="TU818_001588"
     CDS             complement(2578..3231)
                     /locus_tag="TU818_001588"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924386.1"
                     /translation="MKQRKKLSSSVCSSIILACLFRAPTVLAEEKTAAKAISKELQRV
                     KKAPLKTEEASQESSPDTQDASSVATESSLGEQLILTGDNLLKNPQFDQTSPAQEHQS
                     TSLWSKESANDWKDYKDASKSQGCPKIAVSDNKLTMTSDGNQRFRGCVHQTVAINPDK
                     QYLLTFDIETKDKTGQAFARIIEEIKQGSGAAKEQRLWLRWQQELRKNTKKSFISLS"
     gene            complement(3271..3900)
                     /locus_tag="TU818_001589"
     CDS             complement(3271..3900)
                     /locus_tag="TU818_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL0924387.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAMACSLAGIEGGIKTIEV
                     AYTNPFASQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIAYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDVMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            complement(3902..4903)
                     /locus_tag="TU818_001590"
     CDS             complement(3902..4903)
                     /locus_tag="TU818_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL0924388.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGHACQAQLYYGGSEVNIARTLS
                     GFRAESSLLTALPDNQVGRSVEAFLKQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKDLDYGKLFEEVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKTLFSHFAQYADLIFGMEPLMCNQADHAMFDRAKAGQGAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASLKCTVADDQLFVPVSQVDRVMKGNREVRR"
     gene            complement(4936..5577)
                     /locus_tag="TU818_001591"
     CDS             complement(4936..5577)
                     /locus_tag="TU818_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL0924389.1"
                     /translation="MKIALINENSQAAKNSIIYETLVSVTNKHGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREVLQQ"
     gene            complement(5612..6406)
                     /locus_tag="TU818_001592"
     CDS             complement(5612..6406)
                     /locus_tag="TU818_001592"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL0924390.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDQGLAAYREFGIKAHGYVCDVTDEVGIQEMVAQIEKEVGIIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            6715..7149
                     /locus_tag="TU818_001593"
     CDS             6715..7149
                     /locus_tag="TU818_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL0924391.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSVVLQSKTQALMLCDLLGGTPFKVAATLMEELSESTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQIVAKLLTTAKEGISNWKSLSGEADEADLDEGGI"
     gene            7149..8348
                     /locus_tag="TU818_001594"
     CDS             7149..8348
                     /locus_tag="TU818_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL0924392.1"
                     /translation="MTRQIKEVTLEPLIQAEVYSQQPYLTKADIEAAILLALKQIRLN
                     MDYFGTDFPRPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGNDTIKSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSCMAEWKLLKTPEARQAALKAADKLIERYQEKGGFIQ
                     AWGQLGKAEDYRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGM
                     THYFLNRLPKDQVSYWDLIFEDGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQ
                     AAMHCMLRSLIDSYANKDIKPGAPLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWTPYW"
     gene            8394..8882
                     /locus_tag="TU818_001595"
     CDS             8394..8882
                     /locus_tag="TU818_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL0924393.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKPVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            8897..9676
                     /locus_tag="TU818_001596"
     CDS             8897..9676
                     /locus_tag="TU818_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL0924394.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDDWI"
     gene            9663..10484
                     /locus_tag="TU818_001597"
     CDS             9663..10484
                     /locus_tag="TU818_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL0924395.1"
                     /translation="MTGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALENNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDTLTQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            10884..11885
                     /locus_tag="TU818_001598"
     CDS             10884..11885
                     /locus_tag="TU818_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0924396.1"
                     /translation="MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMI
                     IDENQTSSQEIAQFLQGAFDKERHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
BASE COUNT         3478 a         2845 c         2448 g         3588 t
ORIGIN      
        1 agctcagggg ggattttaac ttattactaa tgtgcttgaa tggctatgat aaggccttaa
       61 aagatagctg cttaaagtca tttcccacct tttgatagag gtataagcct gatttttcaa
      121 gactcaattg accattaacc acctccttag cctgattgta tttgaccacc gccaacaggc
      181 cttgtttctt atcatggatc agctgaagct tactgtcatt tcgaagcacc tcaatacgtg
      241 cttcgctgca caccttgtca aagtctgctt tgctgatatt tggaagtagg gtgtaggcat
      301 agctatcact agcctgagaa tgagtttgac tgattgtgat aaagctttgg gagatgaggt
      361 ctttattgtt actatttgta ttaatctcag accaacagcc tgactgcacc tttcgcgata
      421 gcgctaatgc ggttggcttg gcaaaaaggt aaccaatatt agcttgaccg tctttagaaa
      481 gtagtaaaag actggtcaca tcatctcgat acaggatctc ctctgttagc gctgtctcct
      541 gcccattgat aaaaagagtg tagctgttgt ctgggttttc tttgcgttga tcaatggtag
      601 tagtcactgc ctgatgtgtc tgactagtga tggcggtgcc aagaaaaaca atttggtcat
      661 ctaagatcgt ccaagacttc ttggcactca ctgtcctatc ccaattttga aaatccataa
      721 cagctaaagc tgttttgtct cccgccttga tcgctccaac aaaggacgat ggcagggtag
      781 acatgcctgc tttttctttg gccttttctt tataatcatt ggttagcttt tttaaatagg
      841 ctactgtcac gtcctctcgc ctgacctctg cttccgttgt tccagccatc tttaaaggat
      901 taacagtcgg ccaaaagtgg tctgagtaat gacccaaatc actgttataa aggtaaaaca
      961 tgccatctcc tgtataccaa ccacgtgtat tttcatcgtt catggcttca aaattcagag
     1021 ttttgttgga atgcatggat aaagcaaagg caaaatcctt ttccgcattg tagtaggcca
     1081 atttatccat ctggttaaaa agagataggt agctcttaac tggactggct tggattgtgg
     1141 tatcctccaa gagctctttg aatagcttca tgtcatagta gcttgatagg ctctctaaaa
     1201 tagtctcctg attatggaag gccaaaacag ccttgatctt acccttgatc ctgattttag
     1261 cttgctctgg caatgcctca gccagtctta gcattcctct tagtgcttct aaggctgcct
     1321 gccttgagga ggcattttca cgactgatgg agcgcccacg actcatatcc atgagctccc
     1381 catgaaccat caagggcaag aaggcttgct caatccaatg agtcatgacc tctagctttt
     1441 gctggtctag gctagtagct aatagctgaa gtaatggtac cagctgagac aagccatcaa
     1501 taaggacatt gccataggct ccagtgtagg cgacattggt atggtcaata taagagccat
     1561 cttcataaaa gccctcaccc cttgatccct ttggctgaaa agcaaataag gtatctaggg
     1621 ctgctatact gtcttgaagc gctttcttat catgctttaa cagagcttca ataatcttca
     1681 ctcgtcccat atcaacaagg ttacccccaa tggccttaaa aggattcaca agggttaagc
     1741 gaaattgtct aggattagga acaaagtgag aaattccttt agtatagcgc ttgatctcct
     1801 cttgagtgac ataagggtaa atgaaggcta gggtattgac aatagctctt ggggtaccaa
     1861 tttcaaaatc ccaccaatta gccttgcctt caatatcctt ttgcggatga tagtaattaa
     1921 gtgtcagcca ggctaattta tccttgatca gtcttatcag ctccttatcc tgataatacc
     1981 tagaggctag gctactcacc tgcttggcca tttcctctaa acgcctacag gtagctgtca
     2041 tatgagacga ttgatgaaga tccgccaaat cactccaaag gtatgtgctt ttctgatcct
     2101 tggtcagatc agctagattc ttggtcacgc tgtcgtccag tttttggttt aatgccacca
     2161 tggctggact tgatcggtca aagttttctg ctcccaaaat cacctcacac cactttgtga
     2221 tcaaggaggt tgtttgaggg gcttctgctg ctaaaatctc aactggtacc gttgctactc
     2281 tttgcccctc ttgatccaac acctctaaaa gcgttttccc ctgcgccaaa ggaattaaaa
     2341 gaccattttc cacgcgcaca atgttgctgg actccgctgc aatctgataa tgatagtcag
     2401 ccatttccat gaggtagtgc ttatttaaag gcaggacgat ttgctcctct aagtaatgtg
     2461 aagcaatctt gatgtcatca cttggcttat caccagcctc tctcaaagaa aggttatcaa
     2521 agaccacctg tccatgaccg gcctcataaa agagctctag cttgatttga ttaaccttta
     2581 gcttagggat ataaagcttt tcttggtgtt ttttctcagt tcctgttgcc atcgaagcca
     2641 caagcgttgc tcttttgcag caccagaacc ttgctttatt tcttcaatga tacgcgcaaa
     2701 agcctgacct gttttatcct ttgtctcaat gtcaaaggtc agcaaatact gcttgtctgg
     2761 attgatggca acggtttggt gcacacagcc tctaaatctc tgattgccat cgctagtcat
     2821 tgtcagcttg ttatcagaga cagcaatttt aggacagccc tgactcttac tagcgtcctt
     2881 ataatccttc caatcatttg cagactcctt gctccaaagg cttgtacttt gatgctcttg
     2941 agcaggactg gtctgatcaa attgaggatt tttaagcagg ttatcacctg tgagaatgag
     3001 ctgctcccca agactggatt ccgtagctac tgacgacgcg tcttgagtgt ctggggagct
     3061 ttcttgagaa gcctcctcag tttttagtgg tgctttcttt accctctgaa gctccttgga
     3121 aatggctttt gctgctgttt tttcttctgc taagactgtt ggtgcccgaa ataaacaagc
     3181 tagtatgata ctagagcaaa cagaagatga tagttttttt ctttgcttca tctgatacct
     3241 ccttgctttt ttaatgtttt atgaccgact ttaacagcta ctcatgtaat ctgcagccct
     3301 tgctgtgatt gcctgaaatt gaccctgagc tgccaattga ttaaattctc ctccaactcc
     3361 cagcacctga gcacctgcgg caaaccagtc tgacacattt gtgacagtta cgccacctgt
     3421 taccatgaca tcaacctgcg gcaaaggaga tttgattgcc ttaataaagg acatgccaac
     3481 tgtggcacct ggaaagacct tgaccatctc tgcacctgat tccaaggcag tcacgacctc
     3541 ctcaatagtc atacagcccg gaatataagc aatagcatat cgatgacata ggcggcttgt
     3601 ctgcctgcta aagctaggag acacaataaa ttgagcaccc gctaaaatag ctagccttgc
     3661 tgtgacatca tcaagaaccg tcccagcccc gatcaggatc tctggatcat tgccaactgc
     3721 ttcacgcagg cctgcaataa cctgactggc aaagggatta gtataggcca cctcaatggt
     3781 tttgatccca ccttcaatac ctgctaggct gcaagccatt gcttcttttt tagaagctcc
     3841 ccgaacgact aaggctaatt tattggcttt tagccttaac atgatttctg attttctcat
     3901 attaccttct tacctctcgg tttcccttca tcaccctatc aacctgacta acaggaacaa
     3961 agagctgatc atcagcaact gtacacttaa gactagctgt cgcagcagca aaatcaagcg
     4021 cagcagcaat agcctgtcct ctcatcaatt gatataagca gcctgcaaca aaggcatcac
     4081 cactgccaac tcgttgcaaa acaggcgttg atagctcaat ggagcgatgt aactgcccat
     4141 cataggcata ggctaggtaa tgattgattc cttggtcatc gatgtgacgt tccgtgtgaa
     4201 aaatggcttt taagtgatat gcctcatata aggcagccaa gcgctccttg acagcacctt
     4261 gacctgcctt agctctatca aacatggcat gatcagcttg attacacatt aagggctcca
     4321 taccaaagat caggtctgca tactgtgcaa aatgagagaa caatgtcttt gcctccctga
     4381 ctgaaatcat cgagctgcga aaattcaaat caaaggaaac acagacctgc cgcttcattg
     4441 cctcaatagc cagctgctca acaaggtcct gactgacttt tcctaaagcc aaggtaatgc
     4501 cactaaaatg aaaatgagta acttcctcaa atagtttacc ataatccaga tcttttgggc
     4561 ccaataaact aaagctagag gcagagcgat cataagcgac ctgactagga cggcagccaa
     4621 agccattttc caaataataa ataccaaccc gatcaccaca ccattgcaca tgctctgtgg
     4681 caacaccgct ttgcttcaaa aaggcctcaa cgcttcgtcc aacctgatta tcaggaaggg
     4741 cagtcagcag gctactctct gctctaaagc cactaagcgt tcttgcaata ttaacctctg
     4801 agccaccata atacagctgt gcttgacagg catgtcctaa cgtctgaaaa tgactgggac
     4861 tgatgcgaat cagcggctct cccaccaata ataccttggt cataggggta tcctttctat
     4921 agctgcagat aagacttatt gctgaaggac ttctcttagg tagtcgacaa ggtctgatgg
     4981 ctcggcatta gcaaagaaat aatgctggaa gtgctctcca gaaatggttt ccttcaagaa
     5041 atcttgatca atctccttta acacctccaa caaagaacga taagtcacag ccttcaattc
     5101 gctcaaaatt ctagcgttac gttgctctgg gatggcccgc tctttgggat agccgccccc
     5161 catcggctca gcaaataagc gctcaaacat cagggtcagg ttaagctctg ccccccaacc
     5221 aaagcccttt gcaaatggaa tagacaaggc attgccacca ttaatctgag caaaaaggta
     5281 ggcttctgtt ggctcactag caaagccaca ggtcacacct ggaaagctat ttaaggccag
     5341 catagcaccc acaccagtcc cacagcccgt tacaacaaaa tcagctgcct tacttgtcaa
     5401 taaaatagaa gctagtagcc cgttttgcac ataggtcagc tgactttcgc cctccttgcc
     5461 atacatacca tagttaaaga cctcatagcc atgcttatta gtaacagaga ctaaggtctc
     5521 gtaaataata ctgtttttag ctgcttgact gttttcatta attaatgcaa ttttcatctt
     5581 ctgtaatctc ctttgatgct tttttgtttc tttacggttg tttgccaatg taagctaaaa
     5641 tgcctccatc aacataaagg atatgcccat tgacaaagtt actcgcctca ctagccaaaa
     5701 atatagctgg accagccaga tctgctggtg ttccccaacg cgctgccgga gtcttagcaa
     5761 taataaactg atcaaagggg tgacggctgc catcagcctg acgctctctt aaaggtgctg
     5821 tctgaggcgt tgcaatatag ccaggcccaa tgccattgca ctggatattg gcttctccaa
     5881 attctgaagc gatgtttttg gttaacatct taagaccacc cttagctgcc gcataagcac
     5941 taaccgtttc acgaccaagc tcactcatca tcgaacagat attgatgatt ttcccatgcc
     6001 cttttttaat cattgatggc agaactgcct ttgaaacaat aaatggcgca ttcaggtcta
     6061 tatctaccac ctgacgaaaa tccttagccg tcatctcaag catcggtgtc cgtttaatga
     6121 tacctgcatt attcacaaga atatcaataa taccaacctc tttttcaatc tgagccacca
     6181 tctcttgaat ccctacttca tcagtgacat cacaaacata gccatgagct ttaatgccaa
     6241 actctcgata agctgctaat ccttgatcca ctaaatcctg cttgatgtca ttaaagacga
     6301 tctttgctcc agccatggca taggccttag caatctcaaa gccaatccca tacgaggctc
     6361 ccgttatcaa ggcaattttg ccctctaaag aaaagaaatg ttccattgtt ttacctctca
     6421 atctcaatat ttaagtaaac ctgtttatca aaactatagc aagactaatc cattttgtca
     6481 atcattttag taaaaacaca aaaaagagct aaagtttttc ttattgtcat tatcgaggaa
     6541 ggcttcttag ctatattttt cttgctctta ctcgctttac ttcctataag gatcccaaaa
     6601 attaggccat attgatcgct tattttgata aaataacaaa aaagtgttga caaacatttt
     6661 tgaaagcgct ataatttttc tgagtaaacc ggtaaactaa aaaggagctt attcatgatt
     6721 tctattattg ttattggtca tgggcatttt gccagtggta ttgtctcgtc tttagagtta
     6781 attgcaggca agcaagaggg cataactgct attgatttta ctgctgagat gaccgctgct
     6841 gatgtgcatg agcgcctatc agtagtctta cagtcaaaga ctcaggcact tatgctttgt
     6901 gacttattag gcggcacccc atttaaggta gcagctacct tgatggagga gctttctgag
     6961 agcacacttg atgtcctgtc tggactcaat ctagccatgc taatagaagc agtctttgct
     7021 aggcaagagc agcttgatct agaacaaatt gtcgctaagc tattaaccac agccaaggaa
     7081 gggatcagta attggaaatc cctctctggt gaggctgatg aagcagacct tgatgaagga
     7141 gggatttaat gactagacag atcaaagagg ttacccttga gcctctcata caagcagagg
     7201 tctatagcca gcagccatat ctaacaaaag ctgatattga ggcagctatt ttattagccc
     7261 ttaagcaaat ccgattaaac atggattatt ttggtactga tttccctagg ccagccacta
     7321 aggacaattg ctacccaatt atggataata ccgagtggac caatggcttt tggaccggct
     7381 gcctatggct ggcctacgaa tacactggta atgacactat caagtcacta gcacaggcaa
     7441 atgacctgtc cttcttagaa cgcgtcacca aagacattga gcttgaccat catgatttag
     7501 gatttcttta ttcaccctct tgcatggctg agtggaagct tttaaaaaca cctgaagcca
     7561 gacaggcagc cttaaaggca gcagataaat tgattgagcg ctatcaggaa aaaggcggct
     7621 ttattcaagc ctggggacaa ctcgggaaag cagaagatta ccgcttaatt attgattgtc
     7681 ttttaaatat ccagctactc ttttttgcca gtcaagaaac aggagatgac aggtatcgtc
     7741 aaatggctat caatcacttt tatgcctcag ccaacaatgt gattcgtgat gacgcctctg
     7801 cttatcatac cttctacttt gaccctgaaa caggtgatcc aatcaaagga gttacacgcc
     7861 aaggctacag tgatgactcc gcctgggcca gaggacaagc ttggggaatc tatggaattc
     7921 ccttgaccta tcgcttcttg aaggatccac agctaattgc cttatttaaa ggaatgacgc
     7981 actatttcct caatcgcttg cccaaggatc aggtatccta ttgggatttg atctttgaag
     8041 atggcagtgg tcagtctaag gacagctccg caactgctat tgctgtttgt ggtattcacg
     8101 agatgttaaa acatttacca gagaatgatc ctgacaagaa agcttatcaa gctgccatgc
     8161 actgtatgct cagatcatta attgatagct atgccaacaa ggacatcaag cctggtgctc
     8221 cacttttacg tcatggcgtt tactcttggc actctggcaa gggcgttgat gagggaaata
     8281 tctggggaga ttactactat ttagaagccc tgctgcgctt ttacaaggac tggacccctt
     8341 attggtaggc tgatagcatt tagcctacaa agactattgt taaaggagat attatgacac
     8401 caccaaacat tatcatgacc agagttgatg agcgtttgat tcatggtcaa ggccagctat
     8461 ggatcaaatt tttaaattgc aacactgtca ttgtggctaa tgatgccgtt gctgaagaca
     8521 aaatccaaca gtctctgatg aaacctgtcg ttccatcaag cattgccatg cgcttttttt
     8581 ccattcaaaa ggtgattgac gtgattcaca aagcaagccc tgctcagaca atctttattg
     8641 ttgttaagga tttagaagac atcaagcgct tggttgaagg aggggtgccc attaaagagg
     8701 tcaatcttgg aaacattcat aaaacagacg ataaaatcgc cattacccaa ttcatttcgc
     8761 taggcgacaa ggacaaggct attattcgga cattgactca cgatcatcat attgtcttta
     8821 acactaaaac aactccagct ggcaatggtg cctctgaggt taatatttta gattatattt
     8881 aagaaaggaa attgatatgg atatcaattt gttacaagca cttttaatcg gtctttggac
     8941 agccttttgt ttcagcggaa tgttacttgg tatctacacc aatcgctgta tcattctgtc
     9001 ttttggtgtc ggcattatct tgggggactt gccaacagca cttagcatgg gagctatatc
     9061 tgaattagct tatatgggat ttggtgtcgg tgctggtggt actgtgccac ccaacccaat
     9121 cggacctggt atctttggta ccttgatggc tattaccagt gctggtaaag ttactccgga
     9181 agctgcctta gctctttcga caccaattgc cgttgctatt caatttcttc aaacctttac
     9241 ctatacagct tttgctggtg ctcctgaaac agctaaaaaa cagcttcaaa aagggaatat
     9301 taaaggcttt acatttgccg ccaatggtac catctgggct tttgctgtga ttggcttagg
     9361 acttggttta ttaggcgcct tgtcaatgga tactttactt catttggttg attatatccc
     9421 acctgtcctc ctaaatggat taaccgttgc tggtaaaatg cttcctgcta tcggttttgc
     9481 tatgattcta tctgttatgg ctaaaaaaga gctgattcct tttgtcttaa ttggttatgt
     9541 ctgtgcagct tacctgcaaa ttccaaccat cggtattgcc atcataggca ttatcttcgc
     9601 cctaaatgaa tactacaaca aaccaaagca tgcaacaaca gctgaacaag gaggtcaaca
     9661 agatgactgg atctaataag ctcacaaagc gtgattatct gaaaactgct cttagagcct
     9721 ttttcctgca aaatggcttt aactatagca attatcaagg aataggctat gccaatgtcg
     9781 tttacccagc cctaaaaaag cattttggca atgacaaaac aggcctttac aaagcactag
     9841 agaacaattg tgcattttac aatacaaacc ctcatttcct accttttatc accagcctac
     9901 acctggtcat gctagaaaat aatcggcctg aagaagaaac ccgcaatatc aagatggcac
     9961 tcatgggacc tctagcaggc atcggggata cccttacgca attttgttta gcaccactct
    10021 tttcgaccat tgctgcttcc ttagcaagtg acggcctgat tttggggcca attctctttt
    10081 tcctagccat gaatattatt ctaacagcta ttaaaattgg ctctggactc tatggctaca
    10141 aggtggggac aagctttatt gataaattaa gcgaacaaat ggcaattgta tctcgcatgg
    10201 caaatattgt cggagttaca gtgattgctg gtctagctgc tacttctgtt aagatatctg
    10261 ttcccatcac atttgcagca ggcaaggtcg acgctgcaaa tgcagcccaa aaatttgtga
    10321 ccattcaggg aatgctggat aagattgcac cagctcttct gccagccctc ttcactctct
    10381 tgatgtatta cctcattaaa acgaaaaaat ggacaaccta taaattagtt attctaacag
    10441 ttattattgg tattgttggc agctggttag gggtgttagc ctagcagtct tagagattct
    10501 gttaatcagt attggagggt ctccattagc gatgagcagg tctcttttct attgggcaaa
    10561 gctaagcatt gacaccatca actctcgtag cctcagtcag gtcttttgcc ctgtagagcc
    10621 tttaagcaca agcctttact gctagctgtg atgaaggcgt cctccttcta ctggcttctg
    10681 gcacaattaa tcctttatat ctctacaagc acatgattta gcggctgatt gcgcgccaat
    10741 cttacagaag gtcgcaactt aagaaagagt aggatcattt ttgacctctt caaaggtcat
    10801 attcttggac tgaaatatta aaacaattac cattccatat gttataataa aactactaat
    10861 gatgacaaaa aggggtctat gcaatgcagc gcaaagtaac catcaatgat attgctgact
    10921 tagctaaaac ttcaaaaaca actgtttctt tctacctcaa cggtcgattt gataaaatgt
    10981 ctcaggagac aaaaagccgg atcaaggagg ctattgaagc caccaactac aagcctagca
    11041 ttgcagctcg cagtctcaat gccaaggcta ccaaattgat cggtgtggtt atcggtgaca
    11101 tcaccaatag cttttccaac cagattgtca aaggtattga aagcaaggcg caagaatttg
    11161 gttatcagat tatcatcggc aacagcaact atgatccttc acgtgaggac gaattgattg
    11221 aaaaaatgct taacctaggt gtagatggtt ttatcattca accaacctct aactttagaa
    11281 agtattcacg catcatcgaa gtgaaaaaaa agcgcatggt tttctttgac agtcagctct
    11341 atgagcatcg tacaaactgg gtcaagacca acaattatga cgctgtttat gacaccattc
    11401 agcaatgcat caccaaaggc tatcaaagct ttatcatggt tactggcaat cctaatttgc
    11461 tgagcacacg catcgagcgt gcctctggtt ttattgatgt tttagaggct aaccagctcc
    11521 agtatcgtca aatgatcatc gatgaaaacc aaaccagctc tcaagaaatt gctcagtttc
    11581 tacaaggcgc atttgataag gaacgtcaca atctggtatt tgtcccaaac tgctgggctc
    11641 tgcctaaggt ttttactgcc atgaaggcac taaaggtatc attgcccgaa actggtctag
    11701 ttggctttga taacatcgaa tggactcgct tgtcatcacc aagtattacc actattatcc
    11761 agcctgctta cgaagaaggg gagcaagcaa ccagcatttt gattgatgat atcgaagggc
    11821 atagcaagga agccaagcaa caaatttttg attgtcaggt taattggcaa gaatcaacct
    11881 tctaacagga ttttttcgcc ttctagacct taaaaaatca gccattctaa taacgatgac
    11941 aaagtaacac gaggcttaac gcttgtttgc tagcatcaga aaaaacacat aaatcagcct
    12001 gaactacccg gttgatgaaa caataaacca ttaagcaacg gtcttattcc tcataccaag
    12061 aggagcaagg ccgttttgac gtttttgaca atggtcgtta ttgtaaacgt aacggtagtg
    12121 tattactgac aggctcttca aaaaagctgt cgtccttagg tcatacgagg ccttctttta
    12181 caagcgactg ctacttcttc actactagtg tgatctttta gccaatttct gagaacatca
    12241 tcagtaaaat ctcgcacctg ccaataatgg caagcaagct tttttgacca gcaagttaat
    12301 catgtatcac ttgtgacttc aactcttaac tgtttgtcct ttcaagtcta ctataagag
//
LOCUS       DARYMD010000054        12203 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYMD010000054 DARYMD010000000
VERSION     DARYMD010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12203
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(81..1361)
                     /locus_tag="TU818_001599"
     CDS             complement(81..1361)
                     /locus_tag="TU818_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL0924397.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFLVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIININQFQ"
     gene            complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TU818_001600"
     CDS             complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TU818_001600"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL0924398.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALTKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQARLTQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTSIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLVDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIATNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSNRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPVARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            4550..6349
                     /gene="pepF"
                     /locus_tag="TU818_001601"
     CDS             4550..6349
                     /gene="pepF"
                     /locus_tag="TU818_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL0924399.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVGLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSATIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            6342..6845
                     /locus_tag="TU818_001602"
     CDS             6342..6845
                     /locus_tag="TU818_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL0924400.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGDATEINAFCSLTYQTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKCIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLSQ
                     EPIDQSD"
     gene            7344..8537
                     /locus_tag="TU818_001603"
     CDS             7344..8537
                     /locus_tag="TU818_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0924401.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGS
                     VLLGFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFTSFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALIYTTNATLYAVFGVLFLLIPFVYSNIRVIGIVINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8736..9200)
                     /locus_tag="TU818_001604"
     CDS             complement(8736..9200)
                     /locus_tag="TU818_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924402.1"
                     /translation="MLRLAFSGFLIGQPVMALLLIYLLYVNVAEAILAMTGYVLLLAC
                     FFGFGPWLFWQMACYSMVLVLWGYFLNPLSDRLSQHRLINQALMAGVCTFCYHILLDS
                     CFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKRLSGKKDPKLSA"
     gene            9468..10316
                     /locus_tag="TU818_001605"
     CDS             9468..10316
                     /locus_tag="TU818_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL0924403.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKP"
     regulatory      10725..10821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10868..11431
                     /gene="thiT"
                     /locus_tag="TU818_001606"
     CDS             10868..11431
                     /gene="thiT"
                     /locus_tag="TU818_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL0924404.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFILAKIYYLSLSQVIIEYILAFTSMGLAGLFSKPLTN
                     SLGTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVIFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     gene            11592..12071
                     /locus_tag="TU818_001607"
     CDS             11592..12071
                     /locus_tag="TU818_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL0924405.1"
                     /translation="MAKKVKVKKTLVEQILDKAGIPYQALRINALQGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            12068..>12203
                     /locus_tag="TU818_001608"
     CDS             12068..>12203
                     /locus_tag="TU818_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924406.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     G"
BASE COUNT         3668 a         2691 c         2355 g         3489 t
ORIGIN      
        1 caactttttg ggggcagtac acctggtcct ctctaaatgt ttgttataag ccacccgcta
       61 cagttgacaa ggagcttttt ttactgaaat tgattaatat taataatctt actattacta
      121 ttttcttccc ggacagactt ccggtaagat agctctgctt cttttaaaat atcctctttc
      181 ttctcattgg catcaatatt gaggacaaag ccaaccccta cagacaagac cagcaggctg
      241 tttcctccct gtgataagaa tggaaaggta acccctgttg aaggaatgag gccagaaatg
      301 ccaccaatgt taacaaatac ctgcatcagc atcatgccac caacaccaag agccatcatg
      361 gcgttaaagg gatttttggc cttaatcccg acattcatga ttctcaaaat aagaaagaaa
      421 acaagcgcaa ggatcaatcc tgccccaatc agccctaact cctcaatcac gacagaaaag
      481 acaaaatctg tctgtgcctc tgggagatag ccccgctttt caatcgaatt tccaagccct
      541 ctgccaaacc agccaccatt gctcatggcg taataagaat tagccagctg atgtcccgaa
      601 tctgtcaaat cacgaaaagg attgaaaaaa gcactaaagc gcttggcaac gtaaccaaaa
      661 actggaatct tagccacctt ttcaacacca atgacagcaa tcattcccaa aaaagcagtt
      721 gacaaaccag taattagcac taaaatggca gaaaaccaac ggtagcctat accactgacc
      781 aaaaacatga taatagctgt caacacgata atagaggcat tgcccaaatc aggctgcgca
      841 gcaaccagca caatcataat caaggaataa acacgccaat cacgcaggtc accccactct
      901 gttggccacc atttgcgacg cgtcaaggcc tgataatcat actgatgaat cttttcctgc
      961 atctttgaaa aggtgagtgc cagataccaa accatgatga tcttcagata ctctgctggc
     1021 tgaaacctca gaggcccaag gacaatccag ccatgcgcgc cattaatcgc tgtcgtaaaa
     1081 aagcgagcag caatcaacag cagtatttca agcagcataa caattgttaa aaccttggta
     1141 ttggtcaaaa aatttagctt tagcttgtaa ataaaggtaa tagcaactaa gctgacaacc
     1201 caaaagagcc cttgattggc aactgaccga aatggattgg cctgagcctg aatcaagcta
     1261 acactggttg tggaataaac catgatcagc ccaatcacag ataaaatcag ataaggtagt
     1321 aatatggagt aatttagcaa atgcctttta tcaattttca tcatttcccc tataatcttg
     1381 agataatcat tagcattata tcatctttca ttggtaaaac aaaggaaaaa tacattgcaa
     1441 gcacctagcc aagcatggct ctagacaaag cttgctgtat ccttggaatc gctcaatcta
     1501 aaaaacacag acaagccatt ataacctagt agcctgtctg tgtgagctgc tgattgatct
     1561 tcaacggctt agccggaatt acgaagtcct gtagcaatac cattaatagt tgtgtggatc
     1621 agcttttcat agtcctcatc tagctgctca tgacgaagac gcttaatcag ctcaatctga
     1681 atgtagttta acacattaaa atatgggagg cggaaatcca agctttgctt caaggacggg
     1741 gtttcctcaa gaagctcatc atgctgtgcg atagcaagaa taacgttctt agtcagctgc
     1801 cactcatcaa gaatggtatg aaagacctca cagacctcct tgctttctgc taactgcgca
     1861 tattgaaagg caatgttcat gtttgatttt gataatacca tatcaacatt agacagcaag
     1921 gaatgaaaga acggccattt gtcatacata tgctgtaatt tggctaaatt tccctcttct
     1981 ttatcaataa aacgcttaaa ggcagagcct actgcatacc agcctggaag catgatccgg
     2041 ttttgtgacc aagaaaatac ccaaggaatg gcacgcaggc ctgagatatc tgtaatggtt
     2101 ttacgagcaa cagggcgaga accaatattt aagcttgata cctccttgat cggactggct
     2161 tcaaagaaat aatcatagaa atgcggattg tcaaaaacca gctctcgata aatgcgatta
     2221 ctgtcttcaa caatttcatc catgattttc ctaaagccat caatctcatc aggatttgtc
     2281 agcatacgag tcaccatgcg attgatagaa gcagaaatca gcatttccaa attgtagtaa
     2341 gccacatctt gattgccata tttattttca ataatctcac cctgttccgt caagcggatt
     2401 cggtctttaa tagagccaaa tggctgtgag gtgatcgcct cataggatgg accgccacca
     2461 cgtccaacag tcccaccacg tccatgaaag aaggtgatgc tgataccatt gtcctcccca
     2521 attttggtca gctcattttg cgccttgtaa agtgtccagc cagacgctaa atagccaccg
     2581 tctttgttgc tatctgaata cccaagcata atctcttgat agccagcatt tgtagcaatc
     2641 caagacttga caatatcata gctaaggtat tgtgtcatga tcgctctagc attatccaaa
     2701 tcctcaatcg tttcaaataa aggcacaatc tgcacacgcg cctgacgctg gtcaacgaga
     2761 ccaacctcct ttagcatgat agccagctca aacatatcag aaacactctc tgtatgtgaa
     2821 atgatgtgct gcttaatcac ctcttcacca agcttatcct tgagctcacg tgccgctgta
     2881 tagatagcaa gctccttttc taacagctct gacttttcaa cagctgccga tgagagggtg
     2941 cgagggtctt ctgtcagctc ctttaagagg acctcacatt tttgctcctc tgacaaagca
     3001 ctgtaattct caacaatacc agcatttttc aaaagctcag caacacaggc ctcctgcaca
     3061 ctagaatcct gccgcagatc aatactggct aaaaagaaac caaaaatatc aaccgcttgt
     3121 aggacctctt gcaaatcccc ctcaaccaag gaggaatccc cagctgcaat gagagattgc
     3181 tcaatcatga ccagatcagc cttaaaagct gctgctgtct tataggctgg tgcttgctgg
     3241 tcactgctat tggtcacaat gcttgtaacg cccgactgaa gcgagcctac cgtagcaggc
     3301 attctagatg ctagctggtc tgaggccggc tgaccaatta gctcctgcaa ggtttgggtt
     3361 agacgagcct gaatatagtg aaaagctctg cggtagggct cattctcacg ataaatggac
     3421 tgatcactag atagactggc cagacgctcc acctcaggac tggtctttgt caaggctgac
     3481 gacagcgaaa aggtttgata aagagctgac aatttgtcaa tgtaaaagcg caggataacc
     3541 tcactttgga ctgttgcaga cagcctcagt gtctctgctg tgacaaaagg attgccatct
     3601 cggtcccctc cgatccacat gcccatgtta atcggctttg gattgtccag caagatcccc
     3661 ttgtccttgg ccagcgtctt atacttgctt gtcagcgctg tgatcgcctg tatcagagag
     3721 ctattgtaat actgcatgac attggtaatc tcatttttga ccttgagctt tttctcacga
     3781 atgatatccg tctgcatgag aatatcaatg taacggtaca gctcactata ccatttgttt
     3841 tgattcatga cacccgcctt gacatcacga tagcgacgaa gaaggttatg aatgctattg
     3901 gtcaactcta gaactgtctt tcgctgaacc tgtgttgggt gagctgtcaa gactggaacc
     3961 accgtcaccc tttccaacag ttccttggca ttttcctttt cagcagcaga agcaatggtc
     4021 agagcaagct ttcccagata gtcttgattt gtattgtttt gacgattgat ttcataagcc
     4081 aaatcaacgt cctctgaaat attaatcaac agcggaagaa tcgaaaaata tcgtgaaata
     4141 aattccatat ctttattgct aatcttagcg atcaattgct ctagaagcac ataatcctgt
     4201 ttttcagata ggtctataat ttcctcaatc cttgcaaagg cctcatcacc aatcatgcga
     4261 cgcgtaatgc tctcaagtat ttcctttagg atagcaacct cttcagcaat aatctcctga
     4321 ttattatagc tctctaattt tttgactgac aaatgacgga cttcccttct tatgctagtt
     4381 ttcctcctat cataccactt tttgctaaaa atgtaagcct attggctagg aatgtttgtt
     4441 ttccttgaca tataagattc attggtacaa aaatgtttgt aaagctttta caggctatcg
     4501 cttctaattt ttgttatact ataggtaatt actcatgaag gagaacatta tggaattaaa
     4561 aaaacgttca gaattccctg aaaatgagct ttgggaccta actgccctct acaaagacag
     4621 ggaagatttt ctattggcca ttgaaaaagc cttacaagat gtcggcctat tccaacgcaa
     4681 ttacgaaggc aaattaacaa ctgctcagga ttttacacag gccttgatgg agattgagca
     4741 gatttatatt caaatgagtc atattagcac ctatgccttt atgccacaga ccactgattt
     4801 ttcagatgaa gcatttgctc aaattgccca ggctggtgat gattttatga ccaaggctag
     4861 cgtagccctc agcttctttg atacagccct agctaatgca gaccttgctg ttcttgatga
     4921 attggaaaaa aatccctatt tcagcgcaac tatccgcatg gcgaaaatcc aaaaagagca
     4981 tttgctaagc cctgatgttg aaaaggcact gaccaatcta cgagaagtga tcaacgctcc
     5041 ttacgacatt tacaccaaaa tgcgggctgg agattttgag atggaggatt ttgaagttga
     5101 tggtaaagtc tacaaaaata gctttgtttc ctatgaaaac ttttatcaaa accatgaaaa
     5161 tgctgccatt cgtgacaagg cctttcgttc cttctcaaac ggactgcgta agcaccaaaa
     5221 tgcagcagcc gcagcctatc ttgctaaggt caaatcagaa aagctcttag ctgatatgaa
     5281 gggctatgcg tctgtttttg attacctgct ggctgagcag gaggtggacc gcagcatgtt
     5341 tgaccgtcaa atcgacctca tcatgaccga atttggtcca gttgctcaaa aattcttaaa
     5401 gcatgtggca agggtaaatg gcttagacaa gatgactttt gcagactgga agctagatat
     5461 tgataacgcc ctcaatccag aggtctctat tgatggagct tatgacttgg tgatggcatc
     5521 attagcacca cttggtccag cctatacgaa agaagttgaa cgctaccaaa cagagcgctg
     5581 ggtggacttt gctgcaaatg ccaataagga ttctggtggc tacgctgctg acccttacaa
     5641 ggttcaccct tatgtgctga tgagctggac aggccgtatg tctgacgttt acacgctgat
     5701 ccatgagatt ggccattctg gtcagtttat cttctctgac aatcaccaaa gctacttcaa
     5761 cacacacatg tcaacctatt acgttgaagc accttcaacc ttcaatgagc tgatgctaag
     5821 tgattatttg gaggcacaat ttgacacgcc tcgtcaaaaa cgctttgcac tggcgcaccg
     5881 cttgacagat acttatttcc acaacttcat cacgcatttg ttagaggctg cctttcagcg
     5941 taaggtttat accctcatcg aagagggggg cacctttggt gcagagcagc ttaatgccat
     6001 gatgaaggac gttttaacag agttctgggg cgatgctgtt gagattgatg atgacgctgc
     6061 ccttacctgg atgaggcagg ctcattatta catggggctt tatagctata cctattctgc
     6121 agggcttgtg atttcgactg ccggctacct caatctaaag aataacccaa atggtgccaa
     6181 cgaatggctt gatttcttaa agtctggtgg cagtcgtacc ccgcttgaga cagccctact
     6241 catcggagct gacatctcaa cagacaagcc gcttcgcgat accattcaat tcttgagcga
     6301 tacggttgat cagatcattg cctatacaga ggaaattggt catgactagc atttatgact
     6361 ttagcgttaa aagacaagat ggcactgatt gttcactgga gcaataccaa ggaaaggtcc
     6421 tattagtggt caacaccgcc actaaatgcg gattaactcc tcaatatcaa gcattacaag
     6481 agctttatga cacctacagg gaacaaggct ttgaaatcct tgatttcccc tgcaatcaat
     6541 ttttacatca ggcaccgggt gatgctacag aaatcaatgc cttttgcagc ttaacttacc
     6601 agaccacctt cccacgcttt gccaaaatca aggtcaacgg caaggagaca gagccattat
     6661 tcacttggct caaagaacaa aaaagtggcc cactcggcaa gtgcatcgaa tggaacttcg
     6721 caaaattttt aattgatcaa aaggggcagg ttgttgagcg ctatgcctca aaaacagacc
     6781 ccaaaatgat tgaaaaagcc ctacagcaat tgctttccca agagccaatt gaccaatcag
     6841 actaacgaag tcctatcaaa aaacaagcca agatccttat ttcttggctt gtttttatat
     6901 ctaaagcttc ttgctttgcc gaggagccgc taaaggtcgg ctatttgctt gtctattctt
     6961 caaagaactt ttttgaaggg gaccttgtcc tcacacctaa gcttactttt ttcaatcaaa
     7021 tcattcaagc tgcttcctgt aaggactggt gcacttgagc aatgataact tatgctagcc
     7081 tttttatgtt tatcaaaaag tacctgttca catgatttaa ggacatttac ttcagtcatc
     7141 aacagtaaaa agcattgacg catgtgatta ggattgttaa aatcatctta taaaattaag
     7201 aaaaacacat gactattgaa tgatctaagc tgtgctgcca aaagccctta cccttaatcc
     7261 tatcacagtg gacagcatgc aaatgacctc aggagtttca aatgacattc aaatagattg
     7321 tactgattgg agagtttatc agcatgagat ttcaagggtt aacaagtaac ttttataacc
     7381 tcatttttag taggtcaagt cgcaatatcg cagacagttt ttacatgatt gctttgtctg
     7441 ttggtttact taaggtttac aacattaacg cgggagaact ttcttttttg acattggttg
     7501 gtttattgcc aaatatgctg tcttttgctt atggttcttt aatccataac ttaaaaaatg
     7561 ataaaaaatg gttaattgtc tttcagatga tacagctcat tgtcatcatc agtattatca
     7621 tctgcttaag ctatcagcta ccggttgttg tcatgtatgt gctcaacctt gcctttaact
     7681 tggtcacaac cgtattaaat accattcaaa tgaaaatcgt tcccagaaca ctagacgatg
     7741 attcagacct cattgaaaaa tcagtagata ttcaatatgc tacatcaaac gttctagata
     7801 ttgttagcaa ttttgtgggc tctgttcttc ttggctttgt ttcctatctc gttttactgc
     7861 aattgagcct gcctttcttt ataggagcca tagcttttat ttttaggatt cagcttagcc
     7921 cgtctaagct tagcaccacg actaatgacg agattgaaaa acctgcttct gtaacagaat
     7981 cactacgtgc atttagagag tcgaccttta cttcctttat catcttggta gaagcctttc
     8041 tcagtggagg aaccgattta ttactagcac tccttccatt gtatctactg tctgagggca
     8101 tttcaatcga atacattggc cttgttttag cagctcacag agcagcagat ttattagggg
     8161 ctctggttgc acctcgcatt aaggtatctc cacgaagctt ctttttcatt gattatatcc
     8221 tgtctggaag cagcttcttg ctttgcttta tgattcccta tccgatggta aaattacttt
     8281 tgtttttcat taccttcacg attattggca tatcgggcaa tgtatttgaa aaaatgattt
     8341 atagtgagta taaccacaac aagctcgcct tgatctacac gaccaatgca accttatacg
     8401 ctgtctttgg tgtcctattt ttactgattc cctttgttta tagcaacata agggttatag
     8461 gaatcgtgat caacagcctg acaataatga taggatttgg attactcatc gtccatttac
     8521 agcaagaaag aaaatagctt agttctaaaa ccagcaaaat ggataaagcc cttcaacaaa
     8581 ataagcttcc ttacaaaaag gaatcagaag tcactattaa ataatcaaaa actatcaatc
     8641 gatataagaa gatttaagga gcaaaaaaaa gaaattactg atcggcaaca actgcactac
     8701 taccgggttg ctgcgtcaaa gccagcatta agaccctaag ctgacagctt agggtctttt
     8761 ttgccagata gccttttaag caataaaagc actaccagga aataacccat agtggctaag
     8821 gcattagtca ctgtaaaaag cattcctgcc catatatagc tccaccaaga gatactatag
     8881 aggtaagcaa aacaactatc tagcagtata tgatagcaaa aggtacagac tcctgccatt
     8941 aaggcttgat tgatcaaccg gtgctgcgat agcctgtctg ataagggatt caagaaatac
     9001 ccccacaaaa ccaataccat tgaataacaa gccatttgcc aaaagagcca aggaccaaag
     9061 ccaaaaaagc aggctaataa gagcacatag cccgtcatcg ctaaaatagc ctctgctaca
     9121 ttaacataga gtaggtaaat caacaaaaga gccatgactg gctggccaat gagaaagccg
     9181 ctaaaggcta ggcgcagcaa gaagcaacat acagaaacga tagctagtcg actaataact
     9241 ttggtagaca taatccctct ttgagtgttt tttatctatt atgacagatt ttgcatctct
     9301 tgaccagcat caacagcttt ttgatagatg attacaagac aggtagacta aaatcaaacg
     9361 aaaatagata ggacctgatc tgccaaagct gtcctaagga gctaaaaacc taagaaaatc
     9421 gtaagaccac tttgattttt tgaagcattt aaggtacaat aagactgatg agaagaagaa
     9481 taaaacctat tgttgttgtg gtcttcttta cgctgattgc tactttgtta atcattggaa
     9541 aggctcattc tgataatctc aaaagtaaag agctaaagct tgctaaagca agcattccca
     9601 ctaacactag cacgtccaat aagtcgacta caagcacatc tgaaactact gaatttctac
     9661 taaaccccat tattgatgtt tctggctggc agctgccaag tgacattgat tatgaccttt
     9721 tagcatctaa tatttctgca gcaattgttc gtgtttatgg cggatcacaa attactgccc
     9781 ataataacgc tgcctttact accgggattg ataaatcatt caaaaagcat attactgaat
     9841 ttcaaaaacg acatatccca gttgctgtct atagctatgc tctaggtcgt agtgccaagg
     9901 aaatgcgagc tgaagcaaga accttttaca aaaacgcttc tccttttaac ccaacctatt
     9961 attggattga tgttgaagaa gctaccatga cagacatgaa taaaggggtc aaggcgttta
    10021 gagaggagct aaaacggtta ggtgcagaaa atgttggcct gtatatcggt acttatttta
    10081 tggccgagca ggacatttca acagaaggct ttgacgccat ctggattcct acctacggtg
    10141 gtgattctgg ctattatgag gcagcgccag ataccagcct agattacgac ctgcatcaat
    10201 atacctcaca aggctacctc aatggcttta acaatccatt agatttaaat caaatcgctg
    10261 tcacaaaaga cactaaaaaa acctttgaaa agctttttgg gaaagtaaag ccttaaaggc
    10321 atcgaagcaa gtcgtcaaaa cctttgaatg tcagtcattc cgaatgcctt aaaccctaag
    10381 ctcaaagccc aggtaagcca atcctaaaga aggttgctcc tattcttatt tctttaagaa
    10441 taaagaccct ttcatcaatc taagaaggct aaagattgct ggctgttaaa aaatgctata
    10501 ttgattcctt ctgacgtcaa tttgagcatt aaggacaact gtatttagaa gctgatattg
    10561 ataacaccaa tcactgcttg tttttggttt aaaggctggc tgttagctca gccttttttg
    10621 gtgtgatcag tttttgacta taccgctatg ccaactttgt ctcatgattt caaggccaaa
    10681 ttcttgacat tgctgccatc tcattttata atatagaaaa tataattatc acaaaggagt
    10741 gctttggctg agatcgcgta tgcgaaatcc taaggacctg atcttgttaa tacaagcgta
    10801 gggattgtga ccaatatcat tagcattgga aaacgattct ctttttgtgt gcaaaaggag
    10861 tttttttatg tcaaacaaga caactgttac tgttctgatt gaggctgcta tttttgctgc
    10921 tcttgctatg gctttatcat ttataccaga ttttgccggc tggtttagcc cctcttatgg
    10981 tgctattcct ctcgtcttat tttcgcttag gcgtggcctc aggtatggcc tgctaactgg
    11041 cttgatttgg gggctgctcc attttatttt agcaaagatt tactacctca gtctatctca
    11101 ggttattatt gaatatatcc ttgcctttac ctcaatgggc ttagctggcc tgttttctaa
    11161 gcccttgact aatagtctag gtaccaataa aagatccttc agccttctaa ttgctagcgc
    11221 agctgccttt ttagcgattg gggttcgtta tatctggcat tttatcgctg gtgttatttt
    11281 ctgggggagc tatgctccta agggcacctc tgctatttgg tattccttta ctgtcaatgg
    11341 cacagcaggt cttctaacct ttatcgtgac acttattgcc ctgctcatta tcctaccgac
    11401 acaaccacaa ttttttaagc ctagtaaata agacaagagt tcgaatcgga aaatcataaa
    11461 gctgaggcag gtctgtaaag gcctgctctt tctaagccta gaaaaaggat caaaaaagac
    11521 tttttttcag tctaatggta tactactact gttagactgt ttttgatatt gacacataag
    11581 gaagttaaca aatggctaaa aaggtaaaag taaagaaaac gctggtggag caaatcctag
    11641 acaaggcagg tatcccctat caagcgctta ggatcaatgc cttacaaggt gatttcccag
    11701 acacaatcaa cccatcagat atttataaaa ccctagcact gactggcgat aagacaggcc
    11761 ccttgattgg gattattcct ttgacagagc atttatctga aaagaagcta gcaggccttt
    11821 ctggaaacaa aaaggtctcc atgattcctc aaaaggagct gcaaaaaata accggctatg
    11881 ttcatggtgc aaacaatcca gttggtattc gacaaaggca caattaccct atttacatcg
    11941 accagtctgc actagccaag caagaaatta tcgtatcagc tggtgagctt ggtcgatcca
    12001 tacagatcaa tagtcaagcc ctagcagatt ttgttggggc tagctttgct gacataaagg
    12061 agaacaaatg agacttattg gaaatatgat ttggtttatt ttttcaggct tttgggcctg
    12121 gatttcttgg tctattgttg ggcttatcct atgcttaaca attatcggga ttccttttgg
    12181 gatacaatgc ttcaagatag gcg
//
LOCUS       DARYMD010000055        12164 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.056, whole genome shotgun sequence.
ACCESSION   DARYMD010000055 DARYMD010000000
VERSION     DARYMD010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12164
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            19..537
                     /locus_tag="TU818_001609"
     CDS             19..537
                     /locus_tag="TU818_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0924407.1"
                     /translation="MTNNIAKLIEESGKKIKSISEALDISYPTLSSYNQGIRKPKKEN
                     AQKLADYFGVSVAYILGIDEEKYAPSNLKIVTDSFKTSEITSVTPFKSDMEKLKKGIE
                     LGEIHLSMPLNEVFSDDFRRILSNYLMDYEETFIKDLIKFMNNQGQKSDIWKTWIQTE
                     EFQIRRADRDRK"
     gene            591..1682
                     /locus_tag="TU818_001610"
                     /pseudo
     CDS             591..1682
                     /locus_tag="TU818_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(1797..2189)
                     /gene="rpsI"
                     /locus_tag="TU818_001611"
     CDS             complement(1797..2189)
                     /gene="rpsI"
                     /locus_tag="TU818_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL0924408.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(2209..2655)
                     /gene="rplM"
                     /locus_tag="TU818_001612"
     CDS             complement(2209..2655)
                     /gene="rplM"
                     /locus_tag="TU818_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL0924409.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            complement(3194..4054)
                     /locus_tag="TU818_001613"
     CDS             complement(3194..4054)
                     /locus_tag="TU818_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0924410.1"
                     /translation="MTFVLMTDSTADLDSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDASGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
     gene            complement(4238..4756)
                     /locus_tag="TU818_001614"
     CDS             complement(4238..4756)
                     /locus_tag="TU818_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL0924411.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            complement(4757..5503)
                     /gene="rlmB"
                     /locus_tag="TU818_001615"
     CDS             complement(4757..5503)
                     /gene="rlmB"
                     /locus_tag="TU818_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL0924412.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLCGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFALRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIIPKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            complement(5552..6340)
                     /locus_tag="TU818_001616"
     CDS             complement(5552..6340)
                     /locus_tag="TU818_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924413.1"
                     /translation="MKPMRNVALVISAMLLLSSQAFVSAVAAQDNQPTIAVQAQAAAE
                     ANVSARMRSDQPVIEANIATSQPVSQSTEATILLKDAKGNAINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKAFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSATASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     GKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            complement(6557..6964)
                     /locus_tag="TU818_001617"
     CDS             complement(6557..6964)
                     /locus_tag="TU818_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL0924414.1"
                     /translation="MANSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHY
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAIMGYLDMTGQTERLELLIQWCIKQVENSPQS"
     gene            complement(6957..8300)
                     /locus_tag="TU818_001618"
     CDS             complement(6957..8300)
                     /locus_tag="TU818_001618"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL0924415.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKESGVSPKELADRFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDIYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKEDPLDFALWKSAKLGEISWASPWSAGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTSKTFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAGVNLKYLKNTLQQPTVATAD
                     ASQLAAFITAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARANRDFARADAIRDQLAAQGIKLLDTKEGVRWIRG"
     gene            complement(8418..8954)
                     /gene="cysE"
                     /locus_tag="TU818_001619"
     CDS             complement(8418..8954)
                     /gene="cysE"
                     /locus_tag="TU818_001619"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL0924416.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSRQD"
     gene            complement(8966..9718)
                     /locus_tag="TU818_001620"
     CDS             complement(8966..9718)
                     /locus_tag="TU818_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL0924417.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDSVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKSADMIQFMNNYTTILNTLMSDDNSAADTLDRLYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            complement(9711..11855)
                     /gene="pnp"
                     /locus_tag="TU818_001621"
     CDS             complement(9711..11855)
                     /gene="pnp"
                     /locus_tag="TU818_001621"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL0924418.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKRANGATVVRYGESTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAIQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEAFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEGKHD"
BASE COUNT         3529 a         2831 c         2324 g         3480 t
ORIGIN      
        1 atcaattagg aggaatctat gactaataat atagctaaac ttatagaaga aagtggcaaa
       61 aaaataaaaa gtatcagtga agcgctagat atatcctacc caacactatc tagctataac
      121 caaggaatac gaaaacctaa aaaagagaat gctcaaaagt tagcggatta ttttggtgtc
      181 tcagtggcat acatccttgg aattgacgaa gaaaagtacg ctccgtcaaa tttaaaaatc
      241 gtcactgata gtttcaagac atctgaaatt acttctgtaa caccttttaa aagcgatatg
      301 gagaagctta agaaaggaat cgaactagga gagattcatt tgtctatgcc cttaaacgag
      361 gttttctcag atgactttag acgtattctt tctaactact taatggatta tgaagaaacc
      421 tttatcaaag acttaattaa gtttatgaat aaccaaggcc aaaaatcgga tatttggaaa
      481 acatggatac aaaccgaaga gtttcaaatt agacgagcag atcgtgacag aaaatagact
      541 aatatttctc aattacataa gctccgaaaa cttagaaacg gagaactgtt atgtctgtac
      601 acaaatacca atctacaaaa ggaattacct attttgttaa agtttacctt ggtctaaacg
      661 actacggtaa gaaaaaatat tacactaaac gaggattcaa gacgcgtaaa gctgccaaag
      721 ctcatgaaac tgctgttaat catcagctga atagtggaac ttttgcccat cttactgctc
      781 aaacaaccta tacttaccaa gaactatatc aaaggtggta tgaagcttac aaagataccg
      841 ttgaaacaac tactgcagct aaaacggccg atttatatcg ccttcatatt cttccaacct
      901 ttggagagaa aaagatttca aaaatcagtc cgctagactg ccaaaccttt atcacagata
      961 aagcgaaatc attcaagaac atgaagcaaa tcaagtcata cacctctaaa acctttgaat
     1021 ttgccatcaa tatgaatcat attgaacgta atcctatgag caaagttatt atgcctaaac
     1081 tcaaaaaaac tgtcagtgag aactactgga cagttaacga gttgcatcat tttttgacaa
     1141 tcattttaga aaatgaacct tataaacatt atgctctatt tcgattacta gcatacagcg
     1201 ggttacgaaa aggagagctc tacgccctca aatgggaaga ttttgattct gagaatcaac
     1261 tattaacagt cagcaaaagt ttaggaagaa tagatggtca tgccattgaa aaaggaacta
     1321 aaaatacatt ctcagtacgc tctatctatc ttgatgatga aacctgttct atcctcaaca
     1381 aatggaaaca ggaaactagc aaagaaaagg ggcaattatc agtacagccc ctttctctcg
     1441 acaaagaatt tatgtttaca tactgcaaca gagatggtga gatagaaccc ttacacgctg
     1501 actatatcaa caatattcta aaacgcatta tacgaaagca taatcttaaa aagattagcc
     1561 cacatgggtt taggcacact cacgcaacct tgatgattga aatgggaatt gacccagtta
     1621 ataccgctaa gcgtctaggt catgctagca gccagatgac tttagatact tatagtcatt
     1681 ctaacttaac ctctcttaaa actaggtctc aacagattac caaggtgctt ttttcaacaa
     1741 aaaagcacct tgcgaaaact tcgcaaagtg ctctgaaacg ttggtataac tggatattaa
     1801 cgttttgaga actggctagc tttacgggct tttttaagac ctggtttttt acgttcaacc
     1861 atacgtgcgt cacgtgtaag aagaccagcg cgctttagtg agtcacggaa atctgggtcc
     1921 acttgaagaa gcgcacgagc gataccatga cgaatcgcac ctgattgacc agcataacca
     1981 ccacctacaa cgttaacaaa aacgtcgtat gagccttcag ttgaagtcac tgcaaaaggc
     2041 tgattaatga ctaaacgtag gtcagcatgt gggatgtatt cttcaacatc ttttttatta
     2101 acagtgattt taccagtacc tggaactaaa cgaacgcgtg caacagcgtt tttacgacga
     2161 ccagtacctg catattgtgc ttgtgccatt atttaatgct cctttctctt agataagtcc
     2221 tgaaatatca agtacttctg gttgttgtgc agcatgagtg tgctcaccgc caacaaagac
     2281 ctttaatttc ataccttgtg cacgtccaag agtgttgtgt ggaagcatgc cttttactga
     2341 cttttcaatc aaacgaacgg catttttaga gcgaagctca ccagcagtga ttgatttcaa
     2401 gccacctggg tacattgagt gagtgtaata aaccttatca gttgcttttt taccagttaa
     2461 tttaaccttc tcagcattga taacaataac aaagtcacct gtatcagtgt gcggtgtgaa
     2521 agttggcttg ttctttccgc gaagtacgct agcaactact gcagaaaggc gtccaagtgg
     2581 cacatctgtt gcgtcaacaa cgtaccattt gcgttcaact tggcctggtt tagccatgaa
     2641 agttgttttg ttcatgattt ctcctatacg aattcgtttt tgtttacatt agtgatggat
     2701 gttccggtcc atcgaaggta tttggaaggt tccggggcct ttcaaatggg gtaaacaata
     2761 ccgtctacta tagtatcaaa cttcttaact gatagtcaag tggtttagct ctatttcttt
     2821 gattattttt gctttttcac aagaagaaca ggcttgcttt tgagctggac tattagcctt
     2881 gacttccctc caaaaaatcc gctcagttcc tgttagctcc tatgcaaata acaatacaaa
     2941 gattagtggt ggaatgacca aagctcctgt caactgctaa aacatttgac atctgacttc
     3001 tggcaaatca aaaagccctg ttctgttatg ctagttcctt acctgcacgc gcaccttcat
     3061 tgtcaaacaa ttcattctaa cttttgatta aaaataaaaa atgcgaacac ccatactctt
     3121 aagcggcatc acagctaaaa caagctatag tcgacaaaaa agaattgaaa caagcgcttc
     3181 aatccttttc tttttatctt ttttccttgc cgatgacaaa gaccgctaag gtatctggac
     3241 ctgtatgagc agcaatcacc ggtccgagcg gcagcataaa gacatcactg ataccttcat
     3301 gtgctaatag ctgttctcgt aggtcatctg ccccagtctg atcactagta taggacacaa
     3361 caacagttga atcagcaata tcttttgtgg ctctgtcagc aatttcctta atggcctttt
     3421 tacggccacg aatcttggca ataggaacta attttccgct ggcatcaatc cataagagag
     3481 gcttaatatt cactaggctg cctataaaag cagagccttt tgacaagcgt cctcctcgca
     3541 caagatgaaa aagatcatct actaagaaat aggtgcgtaa gcgaggcaaa ataccttcta
     3601 ttatcgcttt ggtttctaat aggctttttc cattatcacg cgcctccgag gctagcatgg
     3661 tcaaatagcc ctctcctcct gctgcagcca agctatcaac aatctcaatt acagcgtccg
     3721 gatagtcctc caaaaccagc tcacgtgcca tgacagcact ttgataggta cctgatagga
     3781 ctgaagaaaa ggcgatatat aaaagagctt ggttatcagc tgcgtaatgt cgaaaaatct
     3841 cttcaaactg accaacattt atctggcttg ttttgggctg gctcccactt ttcatcatag
     3901 ctagcaaagc atcactcgtt aatctatctg gaccaaccgt cttgtaaacc ttgccatcac
     3961 attcaacagt taggcctact atatcgatgt tatgctcctt tgcccaaaaa gaatctaaat
     4021 ccgctgttga atctgtcatc aatacaaatg tcatctgaac tcccaagtaa cgtcattatc
     4081 gtttaataat caaatgattt tctcatagta taacaaaaaa atatcagcta agaaagcaat
     4141 aagaaccagc tgcctcagaa atgatcaccg ttagatcgta tgagctgctc tagcagcctg
     4201 gagaatcata cctagaaaag ctagcaagat aagcttatta atcatctaat cgattcataa
     4261 agtccttgag ctgattaagc tgcccttgat caaagggacc cagtctaggc tttttaagat
     4321 caatatcctg tgacagctta tctaaatccg acttaacagc attaacacgc tgctcaagct
     4381 ctttagcagt gacacgcaag gcgccttggg aaaagatcgt ccactgttca ttcagatcac
     4441 tagtagccac ctctaccatg gttagagcgg tgtttagctc agcagcagtc cgctcaatat
     4501 agctatcagc tgtttcttcc tcttcggtaa aaataacaga aatcctatat tggtcataac
     4561 gctgtctaag tcctggaaca tactgagcat caaatacgca aataatgtca ctatcatcaa
     4621 aatgcgcata gttgttcagc ttatttagca agatccttct agcttgatcc aattggtttg
     4681 tcttaaaaaa ctgacgagtt gattcccaaa aggcaatcat gttatagcca tcaaccagca
     4741 atagtctttt tttcatctat aatttatttc taaatacttc atacatcaaa atagcagctg
     4801 caacgctagc atttaagctc tgaacatgac ccatcatagg aatggtaatc atttcatcta
     4861 cctgtttttt gatgttagct gaaatgccct taccctcatt gccaataatc aaagccagct
     4921 tgcctgaggt attccacttg tatgatggtg taccagttac atctgtcccg aagacccaaa
     4981 agccatttgc ttttagctga tccaatgctt ggctaagatt tgtcacgcga gcaattggaa
     5041 catgctcaac agctcctgtt gaggtcttag caaccactgg tgtcacacca acagcacgat
     5101 gcttagggat aatcacacca caaacacctg ttgcgtcggc tgttcttaaa atagacccaa
     5161 aattatgagg atctgtcagc ccatctagga tgagcagcaa gggattatcc tcctgctgtg
     5221 ccagctctag cagctcatct agctcagtat aagcaaaggc tgacactcga agcgcaaagc
     5281 cctgatgaac agctcctgct gtcatttcgg tcaaagcttt cttttttgtc caagagatag
     5341 acaccttctt actagtggct aaatccttga tgtgatcaac atgcttacca cacagatcct
     5401 cttgaatgta aagcttattt ccagtattgg ctagtaggct ttcggtaacg gcatggacgc
     5461 cataaacaat atccttggtt tcattgattt ctttagcttt catggttttt attataccac
     5521 gaaagcaata aaatagctct tgctgctctt tttatttcct gtgaacagct ttgatgacaa
     5581 gagcaagtaa agcagctgct gtaattgcaa ttagagatga tagcagccaa ggaaagcctt
     5641 tttgctcttt atcttgggct gtgctatcag aaagcatgcc cttgcctttc tcagcagagt
     5701 ctattgattt ggcagctgat ggtgtgttgc ttgagcttgc ctttaggacc ttatcagatc
     5761 gatgattggt tcttgtcata tgattggcgc tagcagtcgc gctaggcaca ttttggggtt
     5821 gctcagtgct tgtcaccctg ccgctagcag cgggtttagg ctggttatta gctggtactg
     5881 gattgctgtt tttctgttct gtctctgggg tatttttggt tggctttcca tcaaaatgaa
     5941 taggtgctga gctaccacta aaggcctttt ctttatcagg aacactcact gatatactat
     6001 aatcactaac ctttaggttc gtaaggtcaa accatactga aaaccggctt tgaccagcct
     6061 gcatggtata ggctgtgcta ttaatcgcgt tgcctttggc atcctttagt aaaatagtag
     6121 cctcagtgct ttggctaact ggctgactgg tagcaatgtt agcttcaata acgggctgat
     6181 ctgaacgcat acgagcactg acattggcct cagctgctgc ctgtgcttga actgctatgg
     6241 ttggttgatt gtcctgtgct gctactgctg atacaaaggc ctgtgagctt aacagtaaca
     6301 ttgctgaaat aactaaggct acgtttctca ttggtttcat agacattctc ctatcatttt
     6361 attatgactc tttcattata aactattcgg aaaatttttc aatagttttg ttacgttttt
     6421 gttacaaata tttattttat gtttcgtgtg tatctatatt gtgacataac ttttaaacac
     6481 aacataaaaa cactctcatg actttgagcg atggcagatc gctagtgaca cagagaatgt
     6541 tttagatgat tcatcattat gattgaggac tgttctccac ctgcttgata caccactgga
     6601 tcaacagttc tagccgttct gtctgacctg tcatatcaag gtagcccata atagcttcaa
     6661 agcctgttga catacgatag gttactacat cagcattttt agccttggta tggctgttgg
     6721 tattgcggcc tcgtttgtag atgtcttttt ctttttcggt caatagttgt gcttctagca
     6781 tggcctgaat cagagaagcc tgtgcctttg cagaaacata ttttgttgca aggtagtgga
     6841 gcttatttgg cttggtctgg ccttggaaaa tcagatgacg acgaatatag taagaataaa
     6901 cagcatcacc aacaaaggca agggcaatgc cattaatcaa attgacatca actgaattag
     6961 ccacgtatcc acctcacacc ttcttttgta tccaacagct tgatcccctg agctgccaac
     7021 tgatcccgaa tagcatctgc ccttgcaaaa tctcgattgg cacgtgcctc ctgacgctca
     7081 gcaatcagct gctcaatctc tgtgtctagg ctttctgctt caaagacaat gccaaaaaca
     7141 gctagcatct cttcaaatgc tgatttgaca gcctcagaat aggcgccgga gttaatccat
     7201 tttgccatgt caaataagac tgtaatccca tttgctgtat taaaatcatc attcatggct
     7261 gctttgaagg cagtgataaa ggcagcaagc tggctagcat ctgcagtggc tactgtgggc
     7321 tgctgaagcg tgtttttcaa gtatttgagg ttaactccag catcatgaat agctttttca
     7381 gtaaaattaa tcggcttacg ataatgctga gtagccaaga aaaagcgtag cgtttgccca
     7441 tccaccgtct ttagcagatc atgaacagtc acaaagttgc ccagtgactt agacattttt
     7501 tcgttgtcaa cattaacaaa gccattatgc atccagtaat tggcaaaagt tttgctagtt
     7561 tttgcttctg attgagcaat ttcattggta tggtgtggga attccaggtc tgcgccacca
     7621 ccatgaatat caatggtatc tcccaaaagc tcggttgcca ttacagagca ctcgatatgc
     7681 cagccaggac gaccggcgct ccaaggactt gcccaagaaa tctcgcctag ctttgctgat
     7741 ttccataggg caaagtccaa aggatcttcc ttgagagcag tttcggtatc tgtacgacca
     7801 ctagcaccag cctccaaatc agcaatcgtt ttattagcca gtctggcata atttgatgcc
     7861 tttgccacgc ggaaataaat atcacctgcc gactcatagg catagccttt tttgattaaa
     7921 gcagcgataa aggcaatgat ctcgtccata tagtccatga cgcgtggatt tttggtggcc
     7981 ggcttcacac cgagtgcctt ggtatcctcc ataaaggcag caataaatct gtccgccaat
     8041 tccttgggtg atacacctga ttccttggct gccttgataa tcttatcgtc tacatctgta
     8101 aaatttgaaa tgtaattgac tgtatagcct gcgtattcaa agtagcgacg aatcgtatca
     8161 aaggccacag ccgaacgtgc attgccaatg tgaatataat tgtaaaccgt tggcccgcag
     8221 acatacatat tgaccacctt atcagttatt ggtacaaact ctcgcagact tctggtcatg
     8281 gtatcataga tttttatcat cacttttccc ttttgttttt atccttttct cctagactgc
     8341 gcaagctgtc agcaactgag gtaagcatag ggctctaact ctcccgtttt ttggctgact
     8401 gcctctagag aaaactatta atcctgcctt gagggctttt tctcatgcac tcgaacaatt
     8461 tgggctggaa tgccaacgac cgtcacgcca gcaggtacat cagtcaacac aacagctgca
     8521 gctccaacct tagccgattt cccaatctcg acaggaccga taatttgagc atgggcagaa
     8581 atcagtgccc cctcacgaac agtagggtgc cgcttccctc gatcttttcc agttccacca
     8641 agcgtcactc catgataaag catggctcct ttttcaacaa tggccgtctc accaatcacc
     8701 aagccagccc catggtcaat gaaaacacct gaagcaatcc tagctcctgg gtggatttca
     8761 atctgtgtcc aaaatcgcca aaactggcta tgcattcgag ccagcagctt aaagccatgc
     8821 tgccacaaaa aatgtgacag cctgtgcgct gccaaggcct ttaatccagg gtaggttagg
     8881 ataacctcta gggtgctacg tgcagcagga tctagttgct ttacaatatc aatattgtcc
     8941 ttccaccagc ccatttaaac tccttttatg tgtcaatatc agaccaatca acaagaatct
     9001 gctgatcatc aaaggggtca atagcaaccc caaaggtctc gtctatgtca ttattgccat
     9061 ttcttggctg ataaatgtct gctatcttcc atgttaagat aacaccacct gatttcctaa
     9121 aaaggccgcc aaactcctct tgattgtacc atttagcgaa gctctgaaga tttgaaaagg
     9181 caggaacata acgcttcccc tctggagttg acatggttgg aaaaagcctg tcatagtaat
     9241 gctcctcttc cttagggtaa acaaaggccg gcaccagata aagcctatcc agggtatctg
     9301 ctgcgctatt gtcatcactc atcaaggtat tcaaaatcgt tgtgtaattg ttcataaact
     9361 gaatcatatc agcagacttg aacactgtag aattgccaaa atctcccttt ttcttgagat
     9421 taaagcctag cccagcagca cctgcatgaa cagcctcctc caagacagta agagcagagc
     9481 gctctaccca atactgagct tgtgcactct tttgctcctc tttaaaggtc gccatgtcgt
     9541 ccttatctgt gaatacagga aaaatcctta ccccttcaat ctcaatagca tagggctttt
     9601 ttgctgccca caccggatac tggtgaaaag cattaaccaa ggccacgcta tctaaaaaat
     9661 tatcaggggc attgataaag gctcttaaac gaatatctag ttcatttgta ttagtcatgt
     9721 ttgccttctt tttttgcttc tgatttttct ggctttggcg ggcgtggcac caaggctttc
     9781 attgatgcgt caatacgtcc cttatcatca accttaataa ccttaacgtc aacctcttca
     9841 ccgatttcaa gaacatctga gacattggta gtgcggctcc aagcaatttc agagatatgc
     9901 accagcgcat ctgtcttgtc aaagaggtta acaaaggcac caaatttttc aatacggaca
     9961 accttagcat ggtagacctc tcctacctta gcctcacgta ctaggctagc aatgatttcc
    10021 ttagcacgat tgatagcgtc ctgatcactt gagtagattg aaacatttcc ttcctcatca
    10081 atgtcaatct taacacctgt ctcagcaata atcttatcaa tggtttcgcc acccttacca
    10141 ataaccacct taatcttatc aacatcaatc ttgatggtat caatctttgg tgctgttggt
    10201 gccaattctg gacgaggctc agcaatggtt gcctcaatca agtcaagaat ttcaaagcga
    10261 gcctttttag cctgcgccaa ggcttcttct aggatttgag gggtgatacc ttcgatcttg
    10321 atatccattt gcagtgctgt aatcccttgg cgtgtcccag caaccttgaa gtccatgtcg
    10381 ccaaaatgat cctctaaccc ctgaatgtct gttaaaacag tataattggt cccatcagag
    10441 ataagtccca tagcaatacc cgcaaccggt gccttgatcg gcacaccacc agccatcaaa
    10501 gcaagcgtcc ctgcacagat agaggcctgc gaggaagaac cgtttgattc caatacctca
    10561 gccactagac gaatagcata tggaaatgcc tcaaggcttg gaaggacttg tgcaagagcg
    10621 cgctcgccta aagcaccatg cccaatttca cgacgccctg ctgcaccgta gcggcctgtc
    10681 tcaccaacag aatattgagg gaaattatag tggtgcaaga agcgtttttt gtactcaggc
    10741 tcaagcccat caataatttg agtatctccc attggggcta gagtcaagac agacaaagct
    10801 tgagtttgac cgcgcgtaaa gaggcctgag ccatgcaccc ttggtaagaa atcaatctca
    10861 gcagcaagcg gacgaatctc atcaacacga cgaccatcag gacgaacctt atcctcagtg
    10921 atgaggcgac gaacctcagc atgctccatt tgctccaaaa tttcagccac atcacgcatg
    10981 atacggtcat gctcttcgtc tgctgcataa cgctcctcgt atgcagctat gacacgctcc
    11041 ttgacagcct cggttgcggc ttcacgtgct tttttctcct caacctgaat agcctgctgc
    11101 aaatcagcat tgtaagtctc tatgatctca gcctgcaaat cagcagcaac ctgtaatagc
    11161 tctacctcag ccttttcctt gcccaccgct gcaacaatct cttcttgaaa agcaatcaac
    11221 tcctgtatag ccttatggcc aaccaaaagt gcttctagca taatagcctc tggcaattcc
    11281 ttagcaccag attcaaccat attgatcgca tcttttgttc ctgctacggt taactctaat
    11341 aatgaagcct cctgctgggc cttatcagga ttgatgataa attcaccctc aacataggcc
    11401 acctgaacac cagcaatcgg cccattaaaa ggaatatctg aaatcgatag ggctaatgag
    11461 ctaccaagca tagcagccat aggggcacta gcatcttcgt cataagacag gacagtatta
    11521 atcacctgga cctcattacg aaagccctca gcaaacatag gacggatagg gcggtcaatc
    11581 aagcgagcgg ttaaggtcgc atctgttgac ggacgtccct cacgcttcat ccagccaccg
    11641 ggaaatttac ctgcggcata cattttttct tcataattga cttgaagcgg gaaaaagtct
    11701 cctgttgaca tcttcttaga catgacagca gcagttagca ctgtagactc cccataacga
    11761 acgacagtgg caccatttgc tcgcttggct acttgaccga cctcaacaac aagtggtttg
    11821 cctgcaaagg ttgttgtaaa tgtttgtttt gacattcttt ctccttgaac gagctagcct
    11881 accatagccg tttgacccga ccaaagcttg ctagcctttt attttttatg gctatacgtt
    11941 gttttgctac aaagagcaat ctgtaaggaa ttacacactc ctctttgtat caaacgacgt
    12001 atctgctaca ttttaccata aaatagttaa aaattcacga ccctaaaagg cattcctaga
    12061 aaaagtttga aagggctgtc aataccagca gcactctctt ttatcactat agccctacag
    12121 ccaagcacgc taagccgctg atgacgcagc aaaaaaagac ctgc
//
LOCUS       DARYMD010000056        12157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYMD010000056 DARYMD010000000
VERSION     DARYMD010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(152..433)
                     /locus_tag="TU818_001622"
     CDS             complement(152..433)
                     /locus_tag="TU818_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL0924419.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQNKKAKPD"
     gene            complement(466..1233)
                     /locus_tag="TU818_001623"
     CDS             complement(466..1233)
                     /locus_tag="TU818_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL0924420.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFDSTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLTNLLQHVPRSGVDIILYNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQIAR
                     HALKSNGRLAMVHRPDRFLEILDTLKINGLAPKRLQFVYPKLGKEANMLLIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKN"
     gene            1352..2092
                     /locus_tag="TU818_001624"
     CDS             1352..2092
                     /locus_tag="TU818_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL0924421.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDREKPSPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVKIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEEIEEVARRIQAEFDRLDQEMAPFKSNQRRSMLTYLYRIPLG
                     ILLVLILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3091
                     /locus_tag="TU818_001625"
                     /pseudo
     CDS             2411..3091
                     /locus_tag="TU818_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            3072..5315
                     /locus_tag="TU818_001626"
     CDS             3072..5315
                     /locus_tag="TU818_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL0924422.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVELIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQFLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKTISPRSVSDRISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHIPIDKIKLLEVV
                     CSFCYSGLTGHSISVIRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFIIATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLYLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPMTNEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWRRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDTDHVGD
                     MEAVVKAFRVKQIYVSQGSLTNASFVKRLQGLAAKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5428..6489
                     /locus_tag="TU818_001627"
     CDS             5428..6489
                     /locus_tag="TU818_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL0924423.1"
                     /translation="MIAIEKIDALSKESLGLITVVTGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6567..7172
                     /locus_tag="TU818_001628"
     CDS             6567..7172
                     /locus_tag="TU818_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL0924424.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSEFYQAAK"
     gene            complement(7423..8637)
                     /locus_tag="TU818_001629"
     CDS             complement(7423..8637)
                     /locus_tag="TU818_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL0924425.1"
                     /translation="MKYIHSGLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLGHLKPKQASYNFEQ
                     LYQSLQIIGSPAFHRMWERQPRAQHKLEAKRDLSLLLSYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLASLIQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDFIETAMINLDSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKAAAKAFKKLLRHY
                     QQAHQSFPSKTP"
     gene            complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TU818_001630"
     CDS             complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TU818_001630"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL0924426.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIIAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            9943..10647
                     /gene="nagB"
                     /locus_tag="TU818_001631"
     CDS             9943..10647
                     /gene="nagB"
                     /locus_tag="TU818_001631"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL0924427.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDL
                     EAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     DNVVVIIDEAAASELD"
     gene            10819..11535
                     /locus_tag="TU818_001632"
     CDS             10819..11535
                     /locus_tag="TU818_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL0924428.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKKLIKTYLT"
     gene            11627..>12157
                     /locus_tag="TU818_001633"
     CDS             11627..>12157
                     /locus_tag="TU818_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL0924429.1"
                     /translation="MLTALDQDQRVISLTDGSSPSRKQAFTCPACGAAVRLKKGRIIR
                     PHFAHISLSHCQYLTENESHEHLRLKADLYRSLSRSETAEVEAYLPDLNQIADLLVNK
                     HLALEIQCSQLPIKRLEQRSRAYQANGYQVRWLLGRKLWLQKRLTGLQRQCLYFSWQL
                     GFHLWELDVEHHLIRLK"
BASE COUNT         3304 a         2348 c         2831 g         3674 t
ORIGIN      
        1 aagtccttgg aggttttgtt ttgctgcttt tttggtcttg gtctttagta gccttgggca
       61 agcggagctt tgacctagtg tgggtctgtc tcaactgttg tcagctagtc ccatagtggt
      121 gcttggccgc ggcttaggag gcgtcaggag cttagtctgg cttcgctttt ttattttgct
      181 gctctgcaat ataggtgagc ttttgctgtc tggtgtttcg ttttttaaac aaggcttcgg
      241 ctctcatcgc agcctgcttg ctatcaaagc tttcataata cagcaggctg acaggtaagc
      301 gacagcgtgt gtattttgct cctttaccag cattatgggc tttgagacgc ttgtctaaat
      361 ctgttgtata gccagtatag agggttttgt ctgcacattc taaaacgtac atgtaagcct
      421 tttgagttgt catgatgaaa aaacctcttg atgcagaaga gcctgctagt tcttaaaagc
      481 cttgtccttg gctccgaaat aaatctcctt aattgtatcg gtatagtctc cgttgtcttt
      541 atggacaata agtggtggca ggattttcaa gccttccata gaaccatcct tgatggcctc
      601 aatcaagagc atgttagcct ccttaccaag ctttgggtag acaaattgca gccgctttgg
      661 agcaagaccg tttattttta aggtatcaag aatctctaaa aagcgatcag gtcgatggac
      721 catagctaga cgaccattgg acttgagcgc atggcgtgct atctgacaga tcttagccag
      781 atttgttgtg atttcgtgtc tggctaggag ataatgctca gataggtttt tctttgaggt
      841 ctgactgctt ttaaagtaag gaggattata aagaatgatg tcaacacctg agcgaggcac
      901 atgctgaagc aggttagtca aatcatcaca aatcatcgtc acctgatcct ccaactgatt
      961 gagcctgata gagcgctgtc ccatatcggc taagcgtggc tgaagctcaa tttcaacaat
     1021 agaggccttg gtttgtgtac tgtcaaataa gcccactgcc ccatttcctg aacacaaatc
     1081 tacaatgagc ccacgtgatg gaagctttgg aaagcgagaa agcaagacac tatcaataga
     1141 gtagctaaag acctctttgt tttgaataat ctgaacgtcg cttgagaaaa gctggtcaat
     1201 ccgttcacca tcttttaata tcgaatgtag catatcatta ttatagcaaa aataatccta
     1261 tcagagtagg gggtgctgat tgagctttcc ctttaatatt aaaatatttc atggtacaat
     1321 gagtaggatt ataagtgaaa aggagactga tgtgttttac gtctatttac gtggcttagt
     1381 tgtcttttta ttgtgggttg ttaatggtaa tgcccactac cataatgagg ataggattct
     1441 tgataagtct gaaaattata ttctagttgc tccgcatagg accttttggg atcctgttta
     1501 catggcattt gccgcacgtc caaagcagtt tattttcatg gccaaaaaag agctcttcac
     1561 caatcgttta tttgcctggt ggattaagat gtgtggagcc tttccgattg atcgcgaaaa
     1621 gcctagtcca gatgccatta gatatcctgt taatatgctg aaaaaaagca atcgctcttt
     1681 ggtgatgttc ccaagtggga gccgtcatgc gacagatgtc aaggggggcg ttgctgttat
     1741 tgccaagatg gccaaggtca aaatcatgcc agcagcctat cagggtccta tgaccttaaa
     1801 gggcttatta gcaggtgagc gtgttgatat gaactttggt catgcgattg atgtttccga
     1861 cattaagcgt atgaatgatg aggagattga ggaggtagct aggcgtattc aggctgaatt
     1921 tgaccgctta gaccaagaaa tggctccctt taagtctaat caaaggcgct ctatgctgac
     1981 ctatctttac cgtattccat taggaatact tctggtgctt attttggctt taaccatgct
     2041 attttcttat ttagcaagct ttgtttggga tccagacaag caccgctctt aggtcgtgtt
     2101 atggattagc gctgaaggcg cgcaaaaatc agggctttgt tgctactcta ctgagactgg
     2161 cttgcagtta cccttctgac atgttatgtc taggatacga atgctactgg ttactcaagg
     2221 ctacaagaaa gccagcactt tccacagtaa ggggattagg taagccaagg taggttatgc
     2281 ttgtagtgta gctgtatgtt acaatttgat gaggttgaag aggtagtcca ttttggactg
     2341 ctttttttaa tatgctagaa aataggacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaac atgttagaag aattgttctt aaagagtaaa gagatgataa agtcccctta
     2461 ttttctgtca cgttgtgtta ctggtgtgct gtctgtaggg cttttgctgg tgctgtggat
     2521 tgccttgact ggcaaggaaa aagcaagaga ggagtcagct ccatttcctg accattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tggcggcagc
     2641 tgaggatatc gtagtggata ttaagggagc tgttcataag gagggtgtct ataagcttgc
     2701 taagggaagt cgtatcacag atctgattga gctagcaggt ggcttgacag accaagctga
     2761 taaaaatgct attaatctag ctgaaaagct atctgatgaa aaggtcgttt atgttgctaa
     2821 gctgggtgag aatatatcag tcattaaagg atcttcagct gaggctcaat cagcgtctgc
     2881 tgatcatcag aagcctgaaa aggttcattt gaacagagct agtcttgctg atttgcaaag
     2941 cattccaggc attggtgcaa agagagcata ggatattatt gatgtacgag aaagcctggg
     3001 tggctttaaa tctctagaag atctgagaaa ggtatcaggt attggtgcta aaacactgga
     3061 gaagctaaag catgagattt cccttgacta agtattttcc aattgctccg atacaatttg
     3121 cccttttagt gcttgttttg cattatttga tttatcgacc tagctggtta acggctggtt
     3181 tgttagctgg cttgttggta ttattaggct atcgctttgt cctcaagcag gtcttaaaga
     3241 cgcttctttt gctagggctt tttggctgtc tttttgctta tcaaaagggt cagctagagg
     3301 ctaatcagat caatcagcct gatcgcttat caacggttga gctgattcca gattcgataa
     3361 tggtgaatgg tgatcaccta tcctttatcg gtcggcactc ggggcatcat tatcagttgg
     3421 cttatcgcat gacctcaaaa gaagaggcag atttttttaa gcagcagagc caatttctaa
     3481 agctaaaggc tgacatcagg ctagaggaag cagcagggct tagaaatttt aagggcttta
     3541 accatcaggc ctatttagct tatcagggaa tctttagagt aggaaaaatc aaaagcttgc
     3601 agtcattgaa gactatctct cctaggtctg ttagtgatcg tattagccaa tggcgacgtc
     3661 aggccatcgt ttggtgccaa tctaggtttc cacagccgat gagtcattat atgacaggat
     3721 tgttatttgg ctatcttgat aagtcctttg ggcaaatgac agagctatac agccagctcg
     3781 gtattatcca tctgtttgct ttatctggta tgcaggtcgg cttttttctg acctacctgc
     3841 gtcgtggctt ggtctggtta catattccaa tagacaagat taagctactg gaggtggtat
     3901 gttcattttg ctattctggt ttgactggtc atagtatttc tgtgatacgt agcttgctgc
     3961 aggcccagct gcgtcatatt ggtttgacag gactagataa tctagcaatg acttttttga
     4021 tgatgttttt gattaatggt cactttctga tgtctattgg tggtgtcttg tcctttgctt
     4081 atgcttttat cattgctacg gtcagatttg aagagctttc tggcaacaaa cagaggcttt
     4141 tgaaagcctt agccatttcc tttggcattg tgcccttgct ggcctactat ttctcggttt
     4201 ttaatccgat ctcggtagta ttgacagcct tattagccta tttgtttgat ggtcttattc
     4261 taccaggtct agcgatcttg tttttcttct cgccccttgc tgttgtgact gccgtcaatc
     4321 cattcttttt atatttagaa aaggggatcg gcatgattgg aagctatttt agtgctccct
     4381 tggtgttagg aagtcctaca gccttacagc tttgcctttg tatggcttgc ttggctatag
     4441 tgtatgatta tcgagggaat cgaggcttac agttggttgc aggtggtttg ttgttgctga
     4501 cgctatttac ggtaaaatgg cccatgacta atgaggtaac gcttgtagat gttgggcaag
     4561 gagacagtat ttttattagg gataagcaaa atcataccat gctgattgat gtcggaggag
     4621 tgcctgctcc tcaggaaaag gagcaatggc ggaggaaata ccaagcctgt aatgcccaca
     4681 aaacactcat tccctatctt agaagccgag gagtagatac gattgatcaa ttggtgctaa
     4741 cccacaccga tactgatcat gtgggggata tggaggctgt tgtgaaggcc tttagagtta
     4801 agcaaatata tgttagtcag gggagtttaa ccaatgctag ctttgtcaag cgattacaag
     4861 gattagctgc caaggttaag gccattagtg ctggtgatca cttgcccatt atgggaagct
     4921 ttttagaggt gctctatcct tgggagatag gagatggtaa aaacaatgat tctttagtcc
     4981 tttatggcag gctattggat aaaagctttt tatttacagg tgatttggag gcagaaggag
     5041 aagaaaggct gattgctcgt tatcctaagc ttaaggctga tgttttaaag gcagctcatc
     5101 atggttctaa gggctcttct ataccagcat ttttagacca tatccagcct cagctaagct
     5161 tgatttcagc aggaaggaac aaccagtatc agcaccctaa ccccgaaacc ttggcacgct
     5221 ttgaagcgag acacattcct tactacagca ccgcaagcaa gggcgctatt cgcttaacag
     5281 gtcaagctca ctggcaatta gaatcctgta gataggctca ttgaaccaga gatatatgca
     5341 agggcctagg tctgggaatg aagtagagaa tgaaaaagat cagctttagc aaggtcatat
     5401 ttagtaagaa aatgctataa taaaaccatg attgcgatag aaaaaataga tgccttaagc
     5461 aaagaaagct taggcttgat tacggtcgta actggtgagg atattgggca atatagccat
     5521 atgaaggcgc tgctactaaa aaaaatagcc tttgatccgg ctgacttgac ttattcttat
     5581 tttgatatgt ctgaggcttt gtatcaaaca gctgagatgg accttgtaag catgcccttt
     5641 tttgctgacc aaaaggtggt tatttttgat catctgctgg acattaccac tagtaaaaaa
     5701 agctacctaa aggaaaaaga gctaaaggca tttgaggact atttggaaaa tcctgtagag
     5761 accacacgtt tggttatctt tgcaccagga aagcttgatg gcaagcgtcg tttggtcaag
     5821 attctcaagc gtgatgccct tatttttgaa gccagtcctt taaaggctgc tgaaaaaagg
     5881 acctattttc aaaaatacag tcaccagctg gacttgagct ttgctagtgg tgcttttgat
     5941 caattgctgt tgaagtcaaa tgatgatttt agtcaaatca tgaagaatat gaccttcttg
     6001 aaggcctata aaaaaagtgg tcctatcaca gtagaggaca ttgctcaagc gattcccaag
     6061 agcttgcagg ataatgtctt tgacttgaca agattggtgt tacaaggaaa gattgatgct
     6121 gctcgggagc tggttcatga tttgcgccta tctggcgagg acgatattaa gcttattgcc
     6181 attatgctgg ggcagtttcg tctgtttttg cagctggcaa ccttggtgcg gtctggaaaa
     6241 acagaacagc agctagtcac tagcctatca gacctgttag gcagacgtgt taatccctat
     6301 caggtgaaat atgcactcaa ggattctaga gccttgtctc tctcttattt gcagctggct
     6361 gtaaagacct taattgaaac agattatcac attaaaacag gtgtttacac aaaggattat
     6421 ctttttgacc ttgctctctt aaagctagta gcgcattctc agggaaatac tgacctctca
     6481 gacctatgag catcaatcaa attagttgaa agcctctatt ttttgagata agatagactt
     6541 atcataaagg aaaagaggaa agagacatga ccattacatt accggatctt ccgtacgcat
     6601 atgatgccct tgagccttat tttgacacag aaacaatgac gcttcatcat gataagcacc
     6661 atgccaccta tgtggctaat accaacactg ctttggaaaa atacccagag ctaggagaaa
     6721 atttagagga attattagca gatgtaagca gcattcctgc tgacattcgt caggctgtga
     6781 ttaataatgg cggtggccat ttgaaccatg cgcttttctg ggagctgctt tctccagaaa
     6841 agcaagaggt ttctgctgat gtcgcagcag ctattgatga cgcttttggt tcctttgctg
     6901 cctttaaaga gcaattcaca gcagcagcta cgggtcgttt tggctcaggt tgggcctggc
     6961 tggttgtgaa taaggctggt cagcttgaaa tcacatcaac tgctaatcag gacacaccaa
     7021 tctcagaggg caagcagcct attttagcac ttgatgtttg ggagcatgct tattacctca
     7081 attaccgcaa tgttcgtcca aattatatca aggccttctt tgaaatcatt aattggaaaa
     7141 aggtctcaga gttttaccaa gctgcaaaat aatagaagtc agttaccaat ctcagaagta
     7201 gattggtttt ttaagtgtgc taataaacta ctagtgttgg tggtaaaagc ctccaagtct
     7261 tttgaaaata ttctctaacg tgatagacaa tacgtgtaac gttcagagtg tatttgatag
     7321 cttagaagct ttataaaaag ccctgccatc tctctagcga atttacccac tagagagatg
     7381 atagagctgt tttttggtta ttggatctac ctcatacctc agctaggggg tcttgctggg
     7441 aaagctttga tgagcttgtt gataatggcg aagtaatttt ttaaaggctt tagccgctgc
     7501 tttcgttaat tgcttggagg atttgccatc tcggctaaaa atagggtgct gttgatcatt
     7561 ttgctgctct aaatctggta ctataaatgg actatcaagg tttatcattg ctgtttcaat
     7621 gaaatcaggc tcaaatagct caatgggttc aatatcaagc aatctatgca gatcattgtt
     7681 ttgattggca tagttaaagg aagacccatt gatgagacca ttttgacttg gctgttgagg
     7741 atctagggca gccaagaaat gaccagcctc tgataaaata aattctgagt gaaaatgaat
     7801 taaaatctta taattggctt gggggaaatt gtctgggtat gtgatttgga gctgattggc
     7861 tgtgtctaaa tgactagcta ccttattgtg gtatctggct gattcattaa gactataatc
     7921 agattcgtct agggtagcta ggtatctagc caaggcatca gcatctgttt ttcctgctct
     7981 cccataattg tttctaaccc attctatttg ctgcactgac aggacatagc gcagctgata
     8041 gagcttgcga ttgaaggtct gataaggaat atgctccaaa tgatcataat aaagctgaat
     8101 taatgatgct aattggtccc aaaaggcatc tgtcgggctt aaggacggac tgaattgctt
     8161 gagtaattgc tttgtttcag cgctttgccc acttaattcc tcgggcattt ttacatagct
     8221 caaaagtaag ctgaggtctc ttttagcttc aagcttatgt tgagcccttg gctgcctttc
     8281 ccacatgcga tgaaaagcag gagacccaat gatctgcagg ctctgataaa gctgctcaaa
     8341 gttatagctt gcttgcttag gcttgagatg gcctaggtag cccttttcaa tggcctcata
     8401 ggaccacccg tcctgtgcta gctttttggc ataatgcagc agatctttcc tgagctgaaa
     8461 ctgatcagat aggcttgagg gctgttgttt tatatgccgc ttttcaaagg aaataaccat
     8521 gtccttgtaa gcttggtggc tctgctcaaa ggccagcctt gcttgctcat gctttgcaaa
     8581 gctaacaaca aacagcacaa ataataaaaa catgagcccg ctgtgaatgt atttcatcat
     8641 taggctttac ttaacaaaca tggcatcacc aaagctaaag aagcggtaat gctcatcaat
     8701 ggcatgctta taggcttcaa ggacaaagtc acgacctgca aaagcagaaa ctagcatgac
     8761 aagcgttgac ttgggcagat ggaagttcgt tgaaaaagca tcaacaacct taaattggta
     8821 gcctggctta ataaaaatat tagtccaacc agaatctgct agaatttgcc cttggaattt
     8881 gctgccaatc gtttctagtg tgcgaataga agtagtacca acagcaataa tgcgtccacc
     8941 agcggcctta accttcctaa gggtttgggc ggcctcttca gatagcaggt agaattcaga
     9001 gtgcatgtca tgctcatcga tattatcgac agaaactggt ctaaaggttc ctaggccaac
     9061 atggagggtc aggtagacga ggtgtactcc tttggcttct attttttgca gaagttcctg
     9121 agtaaagtgt agtccggctg taggagcagc tgctgagcca ttttccttgg cgtaaacggt
     9181 ctggtagcgc tcagcgtctg ctagcttttc atggatatag ggcggaagag gcatttcgcc
     9241 tagagtctct aaaatctcta ggaaaatacc atcgtatgaa aactcaacga ttcgaccgcc
     9301 atgctctagc tcttgaatga cccttgcctt taggcgtcca tcaccaaagc tgatctgtgc
     9361 accggcttta agccgctttg cgggcttggc taaaacctcc cattggtctc cctgaatgtt
     9421 tttaagcagc aaaagctcaa catgcccatg tgtttccatt ttttcaccgt ataagcgggc
     9481 aggaaggacc cgagtattgt tcatgaccag tgcatctcct ggctctagtt gatcaatgat
     9541 atggtcaaag tggctatctg tcatggtgtg ctcttgatgg tcgataatca agagcttcga
     9601 gcgatccctt tgttcaagtg gtgtttgtgc aatcagctcc tctggtagct caaaatcaaa
     9661 atcgttggta ttcatcttaa ctcctttacc cttcttgtga ggctatttac aatcagccta
     9721 tttatcctta gagataaatc ctttctatta tatcacttgt ccctggctac gtcacctgtc
     9781 atggttatga gacacataga gatgattgat ggccttttac tccttattag ctagtgcttc
     9841 ttagctgacg acaggggata tgagattatg gcttgacaat aattggtata taccatataa
     9901 tagaatcaca aaaggtctat accaatcaaa aaggagaatc agatgaaaat tattcgtgta
     9961 caggatcagt tagagggtgg caaggttgct tttagcctat taaaggaaag cttggcaaaa
    10021 ggggctacaa ccttaggatt ggcaacaggc agcacaccga ttacctttta tcaggagctg
    10081 gttaatagtg atttagactg ttcagccttg accagtatca acttagacga atatgtcggg
    10141 ctgccggttg aaaatgatca gagctatgac tattttatgc gtgaccagct gtttaacgct
    10201 aagcccttta aggaaagctt tttaccaaac ggcttagctg atgacttaga ggcagaggtt
    10261 aagcgctatg atcaagttat cgcagagcac cctattgatt ttcagattct tggaattggg
    10321 cgcaatggtc atatcggctt taacgagcca ggaacctctt ttgcagaaaa gacgcatgtg
    10381 gtggatttgc aggcttcgac aattgaggct aatagtcgct tctttgctag tattgatgat
    10441 gtgccaaagc aggctatttc aatgggaatt gcttctatca tggcatcaaa aatgattgtc
    10501 ctattggcct ttggtaagga aaaggctgcc gctattaagg gcatggtatc aggtccagtt
    10561 actgaggctt tgccagcaag tgtattacag cagcacgata atgttgtggt tattattgat
    10621 gaggctgccg cttcagagct ggattagact attgctgatg gctaacagct agtctgctat
    10681 ccgttgtgct cttttgatac agtgtaggta tctggctaaa ggtttcttgc tgactttagc
    10741 aaaaaatctg atcagttatt aaaagaggct ctttggcctc ttttttagaa ttaaggtata
    10801 ttgtgataaa ctaatgctat gcgtttagat aaattattag aagtgacagg ctttggttct
    10861 agaaatcaag tgaaacaact catcaaagga aggtctgtct tgattgatgg gcaaccagct
    10921 agagctggtt gtcagagtgt tgattcaggt cttcaagtga taatggtaaa tggcaggcaa
    10981 ataaaggcat ttgctcatcg ctattacctg cttcataagc cagcaggggt tgtgtcagct
    11041 tgctctgata ggaagcacca aactgtcatt gatttgattc gtaaggagga tagagtggcc
    11101 aatctttacc ctataggccg cttagataga gatacaacag ggcttgtcct cttgacggat
    11161 aatggtccat tagggtttcg tatgcttcac ccgaagcacc atgtgaacaa gacctacctt
    11221 gtgactgtca atggctcttt ggctgctgat gcggtgcctt tctttgaaaa tggtgttacc
    11281 tttcttgatg gtactcgctg caagtctgcc gccttgcgga ttataaaggc tgatcaaatg
    11341 gagtcacaag cagaagtaac actctctgaa ggaaaatacc atcagatcaa gaaaatgttt
    11401 ttaagctatg gcttaaaggt cacacagctc aagcgaattg gttttgcaga aatagcgcta
    11461 ggggatttag ctgagggagc ttatcgtcag ctaacagtaa aagaaaaaaa gctcatcaag
    11521 acctatttaa cataaaatat tgttagattt gaagttgact gacaggttaa gtccagtgtt
    11581 tttcggatat atgctataga gagaacgata acaactggag acccctatgc taactgcctt
    11641 agaccaagat caaagagtca tctcgcttac agatggctct tccccctcac gcaagcaagc
    11701 ctttacctgt cctgcttgtg gagctgctgt acgcttgaaa aaaggaagaa ttatccgacc
    11761 ccactttgcc catattagcc taagtcattg ccaatacctg actgaaaatg aatcacatga
    11821 acatctcagg ctaaaggctg atctgtaccg tagcctatct cgctctgaga cagcagaggt
    11881 tgaggcctac ctgcctgatc taaatcaaat tgcagacctt ctggttaata agcacttagc
    11941 cttagaaatc cagtgtagtc agctaccaat caaaaggctg gagcaacgca gtagggctta
    12001 tcaggctaat ggctatcagg tgcgttggct cttaggaaga aagctttggc tgcaaaagcg
    12061 tctgacaggt ttacaaaggc aatgccttta tttttcttgg cagcttggct ttcatctttg
    12121 ggagctcgat gtggaacacc acctgatacg attgaaa
//
LOCUS       DARYMD010000057        12004 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYMD010000057 DARYMD010000000
VERSION     DARYMD010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12004
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            64..348
                     /locus_tag="TU818_001634"
     CDS             64..348
                     /locus_tag="TU818_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0924430.1"
                     /translation="MSEEATLVVQLPKVLEKQLRAHYDEMVSTAIERALEDKELYKPM
                     VRMAALSRWLDVSTTTLQKWTREGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            357..842
                     /locus_tag="TU818_001635"
                     /pseudo
     CDS             357..842
                     /locus_tag="TU818_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
     gene            894..1181
                     /locus_tag="TU818_001636"
     CDS             894..1181
                     /locus_tag="TU818_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL0924431.1"
                     /translation="METLWHRELTQQEKVLLEGFAVNDSLLQLAIQKTEELEPKKQNM
                     SYVKGILMNWEARGFITVDQVIASEEDYRPLEIANVEVSEDFLAAMDIWKD"
     gene            1196..1486
                     /locus_tag="TU818_001637"
     CDS             1196..1486
                     /locus_tag="TU818_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924432.1"
                     /translation="MTVYYQLENMLVAGFKSQDEYDRYQALKRDYEGESEDYSFSIRE
                     ITNQLEIICQTSENDFPNLSEALMIDYLELVGELKRYDTNQADRYLGMVRHV"
     gene            1479..1841
                     /locus_tag="TU818_001638"
     CDS             1479..1841
                     /locus_tag="TU818_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0924433.1"
                     /translation="MSERIRTILKKFYVTELQNEVLNQLVNDTGLQTFSNYARRMLFK
                     ETSLFMRFDESQFDELIYSLRRIQNNLRQLSKIAEQSQDSQAYRAMDYSRRLVSHYEK
                     QLTRYHKKKKRKLLSKGA"
     gene            1841..2197
                     /locus_tag="TU818_001639"
     CDS             1841..2197
                     /locus_tag="TU818_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0924434.1"
                     /translation="MDKRRIRNVIKQVFLSEEENQKLLEKMKQDGFTNFSLFARKQLL
                     KPDFETWLVSFPEYQPLTGRLLSVGRTINGIAKSATQFGKISQHDLMELGQLMEELVE
                     LVEKQVKEDKQRIAKK"
     gene            2541..4085
                     /locus_tag="TU818_001640"
     CDS             2541..4085
                     /locus_tag="TU818_001640"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEL0924435.1"
                     /translation="MSEQAQRQELHRKIWAIADDVRGAVDGWDFKQYILGILFYRFIS
                     ENFKTYIEGGEDFNYEEIPDEVITPEVKDDAIKTKGYFIMPAQLFSNVVKTARSNDNL
                     NTELKDIFDAIEASAMGYASENDIKGLFDDVDTRSNKLGSTVPERNERLALILEGIAS
                     LDFGSFEDNHIDLFGDAYEFLISNYASNAGKSGGEFFTPQSVSRLLARIVMLGKDEKN
                     KINKIYDPACGSGSLLLQAKKQFTEHIIEDGFYGQEINMTTYNLARMNMFLHNINYDK
                     FSIERGNTLLDPKHGNDKPFDAIVSNPPYSIKWVGSDDPTLINDDRFAPAGILAPKSK
                     ADFAFIMHSLSYLSNKGRAAIVTFPGIFYRGGAEQKIRQYLVDGNFVETVIQLPDNLL
                     FGTSIATCILILAKNKPTTDVLFIDASQQFKKETNNNVLTEENIEKILKSVEHKNNEE
                     YFAQLISQEKIVEADYNLSVSTYVEKEDTREKINIDVLNKEIAETVKNIDRLRAEIDK
                     IVEELS"
     gene            4087..5331
                     /locus_tag="TU818_001641"
     CDS             4087..5331
                     /locus_tag="TU818_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL0924436.1"
                     /translation="MTYIDEMIKELCPDGVEWKELGEVVDYEQPTKYIVKSKEYSDDY
                     SIPVLTAGQTFILGYTNEVTGIYPASKEHPVIIFDDFTTARKWVDFEFKVKSSAMKLL
                     SIKSDRQDDVSIRYVWHYLGTIKYTPEQHARQWIGTFSKFKIPLPPLEIQGEIVKILD
                     KFTEHVTELTAELTFRQKQYSYFRDKLLSFDDESMGGANDKVYTVQWKTLGEVVNFRR
                     GSFPQPYTDMSFYGGEDAQPFVQVVDVADEGFRLNTKTKKTISQKAIPKSVFVPKGTV
                     IVTLQGTLGRVAVTQYDAYVDRTLAIFDGYKQEVDKRYFAHQLKFIFDREKEFARGST
                     LKTITKQEFSNFKIPVPPLDIQRRIVQVLDNFDTVCNDLNIGLPKEIELHQKQYAYFR
                     DKLLTFTAEGVYTDSTVQTRPN"
     gene            5336..5941
                     /locus_tag="TU818_001642"
     CDS             5336..5941
                     /locus_tag="TU818_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL0924437.1"
                     /translation="MTWVFGPIKVELGAVCDVVRGNGLQKKDFVNEGYPVIHYGQIYT
                     FYGLSARVTKSFVSPEVGQKLKKAKTGDVIVATTSENIEDVGKALVWEGAEDVCIGGH
                     SCVLHTEQNSKYLLYYFQTTVFQKQKEKLVIGTKVIELYPKNLEKAIIILPPVYEQGR
                     IVSILDKFDTLTSDLTQGLPKEIEQRQKQYEYWRDLLLNFP"
     gene            5956..7164
                     /locus_tag="TU818_001643"
     CDS             5956..7164
                     /locus_tag="TU818_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL0924438.1"
                     /translation="MGNDIKFENLEQISDNIISSNKKVHLLYAYNATGKTRLSMELKN
                     KVNETDSDGNSIKHILYFNSYTEDLFTWDNDLENDEDRYLIYDKRTYFGNFLEEQQLF
                     ERAVDNFQKYVGRSIDIEFQDVIETVKDEFGNVQKDNRGEALTISNKKSIRFKVDGHT
                     IKVSRGEERIFVWSVFLTLLEIIIEDLTESADTSEFSKMNYIYIDDPISSLDDTNIIN
                     AAIYLSDVIGSAENTDLKFVVSTHQALFYNLLYNEIRFDRRIKKKVFYVMKATDEIED
                     EKQFKYLLTDVEGDSPFGYHLRVREELRKAIQDEQVEKFHFALFRNLVEKTATFLGYG
                     RWENILLGLDVAGHVITSENIKLYTQLIDLYTHNRHADLEYRELPPQEKNTLINLFNS
                     FDSIYRFKED"
     gene            7167..10262
                     /locus_tag="TU818_001644"
     CDS             7167..10262
                     /locus_tag="TU818_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEL0924439.1"
                     /translation="MTEIIQTDTILEAKNFIVLEKYTKLEKPSTYQTEADLERELVSD
                     LRQQGYEYLNNLTTPEALLDNLKTQMEALNGVVFSEAEWLRFLEEYLNKPSDGLIDRT
                     RKLHDNHIYDFIFDDGHIQNIYLWDKKNISRNKLQVINQMSQVGTSSNRYDVTILVNG
                     LPLVQIELKKRGVAIREAFNQVHRYSKESFNEENSLFKYLQIFVISNGTDTRYFANTT
                     KREKNSFDFTMNWALKNNEPIKDLKDFTATFFSQQTLLNILINYSVFDTSDTLLIMRP
                     YQIAATERIIWKIRSAIDSKIKSGPETGGYIWHTTGSGKTLTSFKAARLATEMDKVDK
                     VFFVVDRKDLDYQTMKEYQRFSPDSVNGSNSTAGLKRNIEKDDNKIVVTTIQKLNNFM
                     SSEAQHEIYNKQVVFIFDECHCSQFGEAQKRLKQKFKKYCQFGFTGTPIKVENALGSE
                     TTASVFGRELHAYVITDAIRDQKVLKFKVDYNDVRPQFKSLETEQDLGKLSAAENKKA
                     LLHPTRITEISAYILEHFNQKTHRQNGKGFNAMFAVSSVEAAKAYYQELQDQQAGKAK
                     PLKIATIFSYAANEEQAAIGEIDDETFSPADLSDISSKEFLSGAISDYNRLFQTNFSI
                     NGNEFQNYYRDLAKRVKSGEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLIQAFS
                     RTNRIYNATKTFGNIVTFRDLEKATTDAIKLFGKTETADILLERSYEDYMNGYIEAGQ
                     EQKGYLEVVKELQERFPDPTTIIKESDKKEFVTLFGQFLRLDNILQNYDDFMSLQALQ
                     ELDVTDIEALADFKGRFHLDDEAVAVLSQLDIPSVREIQDYRSAYNDIKSWYDNERRN
                     QQNNDSEIDWDAVVFEVELLKSQEINLDYILELIFETNQKVSDKDQLIEEITRTIRAS
                     LGQRAKESLIVDFINASDLDSFSEKSDILEQFYTFARQKQKEAVANLIETEGLNVESA
                     SRYIQMSLKREYASENGNALNEALPKMSPLNPQYRTKKQMVFEKIVDLVEIFKGIGGE
                     I"
     gene            10430..11881
                     /locus_tag="TU818_001645"
     CDS             10430..11881
                     /locus_tag="TU818_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL0924440.1"
                     /translation="MENKKDLIQTLAYYQFSLENQYLDRKSARKKPQELLKHLIAFAN
                     ADGGQLVIGIEDEKQDNIITGFKDGRAYPIDDFKKIDHEMRETPLDLSLEEIPVLNHK
                     GEDDLILVISVELSSNRVIAAPNDEVYLRQGDESVKLSYEQRTQLSYDKGQRFFEDEV
                     VPDATLEDIDDGLVQDFKNRFDISERSMEEVLKARRFLVNGKLTKAAILLFAKYPSAF
                     FPQARVRFQRFDGTDMGTGSSFNVIKEVTFDDALPTLIIKVRDFIRTQLREFQYLDDN
                     GQFQILPEYPEFAWFEGVVNAVTHRDYSVYGDHIRVLMFDDRLEIHSPGKLPNIVTVD
                     NIKHECFSRNPRIARTLTEFGWVREMNEGVKRIYSEMESAFLHEPKYLEPGNKVVLTL
                     ENNIVSRHLRTRDSLEKQFSDFGNLTADEQAIVHYMYNSGDKMTTAKAIELTGRSRSF
                     VVKMLHHLRDLEIITWFGSSKNDRNQYYLLVDK"
BASE COUNT         3889 a         1929 c         2655 g         3531 t
ORIGIN      
        1 tgtataataa aatatacaaa tttcggagtt tatttaattg agaaatggaa acgaggtaat
       61 gatatgtctg aagaagcgac tttagttgtt caacttccca aagttttgga aaaacaatta
      121 agggcacatt atgatgaaat ggtttctaca gctattgaaa gagcgctaga ggataaagaa
      181 ttatataaac ctatggttcg gatggcagcc ctttctagat ggcttgatgt gtcaacgaca
      241 acacttcaaa agtggacgcg agaaggaatg cctacaatgg ttattgatgg tgtgactctg
      301 tacgataaac gtgcggttac acgttggttg aagcaatatg aaagatgagg taaagaatgg
      361 ctaatagacg aatgttgagt aaaacggtgg tgcagataca acgattttta cgcctaccac
      421 ttgaagcgca ggcgctttac tgtcacttgg tagtcaatgc agatgatgat ggtattgttg
      481 aagcttttcc tgttatgcgg atgattaatg ctaatgagga cagtttgaat ttattaactc
      541 ttaagcagta tttactcttg ttaaacaatg aaatggttta ctttatcaag gatttctttg
      601 agcagaatac catcaaagca gatcgttaca caccgagtag tcatcgtcaa cttcttatag
      661 attatctgaa ggataatcag ttgttggagt gtctaaatct aggaccacgc ttgattaatt
      721 atcttcaaaa tactcggctc caagttggag ccagtctgga tccagatggg aaccgcaata
      781 taattaaaga taagataagt aaagatagga taggtaaaga taagttaagt caagataaga
      841 taggattaga taatgatcca atctcatcac aactgactga tgacatctgg ttaatggaaa
      901 cactatggca tcgagaatta acccaacagg agaaagtatt attagaagga ttcgcggtta
      961 atgattcttt attgcagtta gctattcaga aaacagagga gcttgagcca aagaaacaaa
     1021 acatgagtta tgtcaaaggg atactaatga attgggaagc tagagggttt ataactgttg
     1081 accaagtgat agcatctgaa gaagactacc gtccattaga aattgcaaat gtagaagttt
     1141 cagaagattt cttagcagct atggatatat ggaaagacta ggggaataat gagttatgac
     1201 agtatattat caattagaaa atatgttagt ggctgggttt aagtcacaag atgagtacga
     1261 ccgctatcag gctctcaaga gggactatga aggggagtca gaggactata gcttttcaat
     1321 cagagaaatc acaaatcaac ttgaaatcat ttgtcagacc tcagagaatg attttccgaa
     1381 cttatcagaa gcattaatga ttgattattt agaactggta ggagagttga aacgatatga
     1441 tactaatcag gcagacaggt atttagggat ggttcgtcat gtctgaacgt atcagaacta
     1501 ttttaaagaa gttttatgtg acggaattgc agaatgaagt acttaatcaa ctagtaaatg
     1561 atacaggctt gcaaacattc tctaattatg ctcgtcggat gctttttaag gaaacatcac
     1621 tctttatgcg atttgatgaa tctcagtttg atgagttgat ttattcttta aggcgtattc
     1681 aaaataattt aaggcagtta tctaaaattg cagagcagtc tcaagatagt caagcctaca
     1741 gagctatgga ctatagcaga aggttagttt cacattatga aaagcagtta acgcgttacc
     1801 acaagaaaaa gaaacggaaa ttattatcta agggagctta atggataaaa ggagaattag
     1861 gaacgtaatt aaacaagtct ttttgtctga agaagaaaat caaaaactgt tagagaaaat
     1921 gaagcaagat ggcttcacaa acttttctct ttttgctaga aagcaattat taaaacctga
     1981 ttttgaaact tggctagtta gttttccaga atatcagccg ctgactggca ggttactatc
     2041 tgttggtaga acaattaatg gcatcgctaa aagcgcaaca cagtttggaa aaatttccca
     2101 acatgatttg atggaattag gtcagttgat ggaggaactt gtagaactgg tagagaaaca
     2161 agtgaaggaa gacaagcaac gaatagccaa gaagtgatag tcgttcagtc attttggtag
     2221 aatagtttta aataaaacaa caaaaacgct gatggtagtc agcgtttttt agcatgtaat
     2281 tgtaaaaaat ccttgtacgg acaatgtgcg gcaccgtata aagtacggga aatcactaaa
     2341 aatggagtta ggtctttgcg agctcagata gtgtatacac actatcgtaa aaatagaacc
     2401 atcagtaaag gtcagactga cactttttga ttgatgctta tattttattt tggggcaaag
     2461 ccccaaaccc cttgagaaaa cgtgtgagaa gtagggaaaa atggtataat agaaatatta
     2521 aagactgtga ggatttgaag atgtcagaac aagcacaaag gcaagagttg caccgcaaaa
     2581 tctgggcaat cgcagatgat gtccgtggtg cggtagatgg ttgggatttc aaacaatata
     2641 ttttgggaat ccttttttac cgttttatca gtgaaaattt caagacttat atcgagggtg
     2701 gtgaggactt caactatgag gagattccgg atgaagtaat cacacctgag gttaaggatg
     2761 atgcgattaa gacaaagggg tactttatta tgcctgcgca gcttttttcc aatgttgtga
     2821 aaacagctcg tagtaatgac aacttaaata cggaactcaa ggatattttt gatgccattg
     2881 aggcgagtgc tatgggttat gccagtgaaa atgatattaa aggtcttttt gatgacgtag
     2941 acaccagaag taataagcta ggaagtaccg tcccagagcg taatgaacgc ttagccctta
     3001 tcctagaagg tattgccagc cttgattttg gtagtttcga ggacaatcat atcgaccttt
     3061 ttggcgatgc ctatgagttt ctgatttcta actacgcttc taacgccggg aaatcaggcg
     3121 gagagttttt cacaccgcag agcgtgtcac ggctcctagc acgtatcgtc atgttaggca
     3181 aggatgaaaa gaacaaaatc aataagattt atgaccctgc ttgtggttct ggttctctct
     3241 tgcttcaagc caaaaaacaa tttacggagc atattatcga ggatggtttt tatggtcagg
     3301 aaatcaacat gaccacctac aacttggctc ggatgaatat gttccttcat aatatcaact
     3361 acgacaagtt tagcattgag cgtggcaata cgctgctgga ccctaagcat ggcaatgata
     3421 agccctttga tgctatcgtg tccaacccgc cttattcaat caagtgggtt ggtagcgatg
     3481 acccgacgct aattaatgat gaccgttttg caccagcggg gattctggca cccaagtcta
     3541 aagcggattt tgcttttatc atgcatagcc tttcttattt gtccaataaa ggcagagcgg
     3601 ctattgtgac cttccctggg attttttatc gtggtggagc ggagcaaaag attcgtcagt
     3661 atttggtaga cggaaacttt gtcgaaactg ttatccaatt gccggataat ctcctttttg
     3721 ggacgtctat cgctacctgt atccttattc ttgctaagaa taagccgaca acagatgttc
     3781 tcttcattga cgctagccag cagttcaaaa aagaaaccaa taacaatgtc ttgacagaag
     3841 agaacatcga gaaaattctg aaaagtgttg agcataagaa taatgaagag tattttgctc
     3901 agctcatttc ccaagaaaaa attgtggaag ctgactacaa tctctctgta tctacctacg
     3961 tggaaaaaga ggatacgcgt gagaagatta atattgatgt attaaacaaa gaaattgctg
     4021 agaccgtgaa aaatattgac cgattgcggg cagagattga taagattgtc gaggagttga
     4081 gctgatatga cctacattga tgagatgatt aaagagcttt gtcctgacgg agtggagtgg
     4141 aaagagttgg gtgaagtcgt tgactacgaa cagccaacaa agtatatcgt aaaatctaag
     4201 gaatacagcg atgattattc cattccagtt ttgacagcag gtcagacatt tattcttgga
     4261 tacacaaatg aagtaactgg tatttatcca gcaagtaagg aacatccagt tattattttc
     4321 gatgacttta cgacagctag aaagtgggtg gattttgaat ttaaagttaa gtcctcggcg
     4381 atgaaactac tctctatcaa gtcagaccgt caagatgatg tttcaataag gtatgtttgg
     4441 cactatttag gaacaataaa atacacacca gaacagcacg cacgacagtg gatagggact
     4501 ttttctaaat ttaaaatccc ccttccccca ctagaaattc aaggggagat agttaaaata
     4561 cttgacaaat tcacggaaca tgttacagaa ttgaccgcag aattgacctt tcgacagaaa
     4621 caatattctt attttagaga taagctccta agttttgatg atgaaagtat gggaggggcg
     4681 aacgataagg tttacactgt ccagtggaaa acgctggggg aggtggtgaa ttttaggaga
     4741 gggtctttcc ctcagcctta cacagatatg tcgttctatg gtggagaaga tgcccaacca
     4801 tttgttcaag ttgtagatgt tgctgatgaa ggatttagac tgaatactaa aacgaaaaaa
     4861 acaatttctc aaaaagctat tccaaaaagt gtttttgtac ctaagggaac cgttatcgtt
     4921 accttgcaag gcaccctagg aagggtagcg gttacccagt atgatgctta tgtcgataga
     4981 acgttagcaa tttttgacgg ttataagcaa gaagttgata aacgctattt cgcacaccaa
     5041 ttgaagttta tttttgacag agaaaaagaa tttgctagag gaagtactct gaaaacaata
     5101 acaaaacaag aattctcgaa tttcaaaatc ccagtccctc ctctggatat tcagcgtcgt
     5161 attgtccaag ttttggataa ttttgatacg gtttgtaatg acctaaatat cgggctacct
     5221 aaggagattg agcttcatca gaaacagtat gcctatttta gagacaaact cttgaccttc
     5281 accgccgaag gcgtgtatac tgacagtaca gtacagacaa gacctaatta ggctcttgac
     5341 ttgggttttt ggaccgatta aggttgagtt gggggctgtc tgcgatgtgg tgcgtgggaa
     5401 tggtttgcaa aagaaggatt ttgttaatga gggttatcct gttattcatt atggacaaat
     5461 ctataccttc tatggattga gtgctcgcgt gacgaaatct tttgtgtcac cagaagttgg
     5521 tcaaaaattg aaaaaagcta aaactggtga tgtgattgta gctactactt ctgaaaatat
     5581 tgaagatgtt ggtaaagcac ttgtttggga aggtgctgaa gatgtttgta ttggtggaca
     5641 ctcttgtgta ttgcacacgg aacaaaactc gaagtacttg ctttattatt ttcagacaac
     5701 tgtgtttcaa aagcaaaagg aaaagttagt gataggaact aaagtgattg aactgtatcc
     5761 taaaaattta gaaaaggcga ttattattct cccacctgta tacgaacaag ggcgtatcgt
     5821 ctccattctt gacaaatttg atacactaac ttctgacctt acccaaggtc ttccgaaaga
     5881 aattgagcaa cgacagaaac agtatgagta ttggcgggat ttactactta actttccgta
     5941 ggaggaagaa tagatatggg aaatgatatc aaatttgaaa atttagaaca gatttcggat
     6001 aatattattt ctagtaataa gaaagttcat ttgctatatg cctataatgc tactgggaaa
     6061 actaggcttt ctatggaatt gaaaaataag gtaaatgaga ctgatagtga tggtaatagc
     6121 attaagcaca ttttatattt caattcatat acggaggatc tttttacgtg ggataatgat
     6181 ttggaaaacg atgaagatcg atatttgatt tatgataaac gaacttattt tggaaatttc
     6241 cttgaagagc aacaactttt cgaacgtgct gtagacaatt ttcaaaagta tgttggtaga
     6301 tctattgata ttgagttcca agatgttatt gaaacagtta aagatgagtt cggaaatgtt
     6361 caaaaagata ataggggtga ggcactaaca attagtaata aaaagagtat aagatttaaa
     6421 gtagatgggc atacaataaa ggtgtctaga ggagaagaga ggatttttgt ttggtcagtt
     6481 ttcttaacgc tccttgaaat tattattgaa gatttgactg agtctgctga tacctcagaa
     6541 ttttcaaaaa tgaactatat ctatattgac gatcctatat cttctttgga tgatactaat
     6601 attattaatg ctgcaattta tttgagtgat gttataggta gtgctgaaaa tactgatttg
     6661 aaatttgtcg tctctactca tcaagcatta ttttataatt tactttataa tgaaatccga
     6721 tttgatagaa gaatcaagaa aaaggttttt tacgtcatga aagctactga tgaaattgag
     6781 gatgagaaac aatttaaata tttgttgaca gatgttgaag gggattctcc atttggatat
     6841 catctcagag tgagagaaga attgagaaaa gcaattcaag atgaacaggt agagaaattc
     6901 cattttgctc tttttagaaa cctagttgaa aaaacagcaa catttttagg atatggacga
     6961 tgggaaaata tcttgttagg tttagatgtt gctggacatg ttataacatc tgaaaatatt
     7021 aaactctata cacaactgat tgatttatac actcataata ggcatgctga tttagaatat
     7081 agagaattgc ctccccaaga gaaaaatact cttataaatt tatttaatag ctttgattca
     7141 atctatcgat ttaaagagga ctaactatga ctgaaatcat ccaaacagat actattttag
     7201 aggctaagaa cttcattgta ctggaaaaat acaccaagtt ggaaaagcct agcacctatc
     7261 agacggaagc agacttggag cgagagctgg ttagcgattt gcggcagcag ggatacgagt
     7321 acctcaacaa tctgacgacc ccagaagctc tcttagataa cctaaagacc cagatggaag
     7381 cccttaatgg cgtggttttt tctgaggcag aatggctgcg ttttttagag gagtacctca
     7441 ataagcctag tgatggtttg attgaccgca cccgaaagct ccacgataac cacatctacg
     7501 actttatctt tgacgatggg catatccaaa atatttatct ctgggataag aaaaatatca
     7561 gtcgaaataa gcttcaggtc attaaccaaa tgtctcaagt tgggacttca agtaaccgtt
     7621 atgatgtgac cattttggtt aatgggctac ccttagtaca aattgagctt aaaaagcgtg
     7681 gggtggctat tcgtgaggct ttcaaccagg ttcaccgtta cagtaaggaa agctttaatg
     7741 aggaaaattc gctcttcaag tatctccaga tttttgtcat ttcaaatggg acggatactc
     7801 gctattttgc taataccact aagcgagaga aaaattcttt tgactttacc atgaattggg
     7861 cactaaaaaa taatgagcca atcaaggatt tgaaggattt tacagcgacc ttcttcagtc
     7921 agcagacact cttaaacatt ctcatcaact actcagtttt tgatactagt gataccctcc
     7981 taatcatgcg tccctatcag attgctgcga cggagcgcat catctggaag attcgttcgg
     8041 ccattgatag caaaatcaag agtggtcctg agactggcgg ctatatctgg catacgacgg
     8101 ggtctggtaa gaccttgacc agttttaagg ctgcgagact ggcgactgag atggataaag
     8161 tggacaaggt tttctttgtg gttgatagga aagacttgga ctaccagact atgaaagaat
     8221 accagcgttt ttcacctgac tcagttaatg ggtcaaatag cacagctgga cttaaacgca
     8281 atatcgaaaa agatgacaat aagattgttg tgacgacgat tcaaaagctc aataacttta
     8341 tgtctagtga agcacagcat gagatttaca acaagcaagt ggtctttatc tttgacgaat
     8401 gccactgttc acagtttggc gaggctcaaa agcgcttaaa acaaaagttt aagaagtatt
     8461 gtcagtttgg ttttacaggc acgccgatta aagttgaaaa tgctttaggc agtgagacga
     8521 cagcttctgt attcggtcgg gagcttcatg catacgtcat tactgatgct atccgtgacc
     8581 aaaaggtgtt gaaatttaag gtggattata atgatgttcg tccacagttt aagtcgttag
     8641 aaactgagca agatttaggg aaattatctg ctgctgaaaa taaaaaagcc ctacttcatc
     8701 caacacggat tacagagatt tcggcttata ttttagaaca ttttaatcaa aagacacata
     8761 ggcaaaacgg taaaggattt aacgctatgt ttgctgtgtc aagtgtcgag gcggccaagg
     8821 cttactacca agagttgcaa gaccaacaag ctggaaaagc taaaccattg aagattgcaa
     8881 ccatcttctc ttatgcagca aatgaggagc aggctgcgat tggggagatt gatgacgaga
     8941 ctttcagccc tgctgacttg tcagatatta gtagtaagga atttttgagc ggagcgattt
     9001 ccgattataa tcgccttttt cagactaatt ttagtatcaa tggcaatgag tttcaaaact
     9061 attaccgtga tttagctaag cgagttaagt ctggagaagt ggatttgctg attgtcgttg
     9121 gtatgttttt gactggtttt gatgcaccaa ccttgaatac tctttttgtg gataaaaact
     9181 tgcgttatca tgggcttatt caggcttttt ctcggacgaa tcggatttat aatgcgacaa
     9241 agacatttgg aaatattgta actttccgtg atttggagaa ggctacgacg gatgctatta
     9301 agttgttcgg gaagacggag acggctgata ttctgttaga gcgctcttac gaggactaca
     9361 tgaatggcta cattgaggct ggtcaagagc aaaaaggata tttggaagtc gtaaaagaat
     9421 tgcaggagag atttccagat ccaacgacta ttatcaaaga aagtgataag aaagaatttg
     9481 tgaccttgtt tggtcagttc ttgcgcttgg ataatatctt gcagaactat gatgatttca
     9541 tgagtttgca ggctttgcaa gagttagatg ttacagatat agaggctttg gcagatttca
     9601 aaggacgttt tcatttggat gacgaagcag ttgcagtact ctctcaactg gacatcccaa
     9661 gtgttcgtga gattcaagat tatcgctccg cttacaatga tatcaagtct tggtatgaca
     9721 atgagcggcg taatcagcag aataacgatt ccgaaatcga ctgggatgcg gttgtctttg
     9781 aagtggagtt gttgaaatca caggaaatca atctggacta tattctggaa ttgatttttg
     9841 aaaccaacca aaaggtatct gacaaggatc aactcattga agaaattaca cgaactatcc
     9901 gtgctagtct gggtcagaga gctaaggaaa gtttgatcgt ggattttatc aatgccagtg
     9961 acttggacag tttttctgag aagtcagata tcttggagca attttataca tttgcccgtc
    10021 aaaaacaaaa agaagcagtg gctaatttga ttgagactga gggattgaat gtagagagtg
    10081 ctagccgcta tattcagatg tcactcaaac gagagtatgc cagtgaaaat ggtaatgctc
    10141 tcaatgaagc acttcctaag atgagtccgc tcaatcctca atatcgtacc aaaaagcaga
    10201 tggtgtttga aaaaattgtg gatttggtgg agatatttaa ggggattggt ggagaaattt
    10261 aattattatt atttcttcta gatatagaag agataaactt taaattagag cttgaaattt
    10321 taagaaatat taaggcatca tatcagtagt ataaaaagct gacttataat ttatttggaa
    10381 acgacagtta atcctaaaat acgatgcttg atatggagga ggcttaaact tggaaaataa
    10441 aaaggattta attcaaacct tagcctacta ccaattctca ctagaaaacc aatacttgga
    10501 tagaaaatca gcacgaaaga agccgcaaga attactcaag catctgattg cttttgccaa
    10561 tgcggacggc ggtcagttgg ttattggtat tgaagatgag aagcaggaca atattatcac
    10621 tggtttcaag gatggcagag cttatcccat agacgatttc aaaaaaattg accatgagat
    10681 gcgggagact cctctggatt tgtctttaga ggaaatccct gtgctaaatc ataagggaga
    10741 agatgacctg attttggtta tttctgttga attatcgtcg aaccgagtga ttgctgcgcc
    10801 taatgatgag gtttatctgc gtcagggcga tgaatcggtt aaattaagct atgagcaacg
    10861 tactcagctt agctatgata agggccaacg tttctttgaa gatgaagtgg tacctgatgc
    10921 gaccttggaa gatattgatg atgggttagt ccaggacttc aaaaatcggt ttgatatttc
    10981 agagcgctcc atggaagaag ttcttaaagc aagacgattc ttggttaatg gtaaattaac
    11041 taaggcagcg attctactct ttgccaaata tccatcagcg ttttttccac aagctcgtgt
    11101 tcgttttcaa cggtttgacg ggacggatat gggaacaggc agtagcttta atgttattaa
    11161 agaagtaact tttgatgatg ctctgcccac cttaattatc aaagtgcgag attttatccg
    11221 tactcagctg cgtgaatttc agtacttaga cgataatggg caattccaga ttttgcctga
    11281 gtatcctgaa tttgcttggt ttgagggtgt tgtcaatgcg gtgactcacc gtgattactc
    11341 tgtctatggg gatcacattc gtgtactcat gtttgatgat agactggaga ttcatagccc
    11401 agggaaatta ccaaatatcg ttaccgttga caatatcaag catgaatgtt tttctagaaa
    11461 tcctcggatt gcgagaaccc tgactgaatt tggatgggtt cgtgagatga atgaaggagt
    11521 gaagcgtatc tattctgaga tggaatcagc ttttcttcat gaacctaaat atttagaacc
    11581 aggtaataag gtagttttga cccttgaaaa taacatcgtg agtcgacatc tccgaacacg
    11641 agatagtttg gaaaaacaat tttctgattt tggaaatctg actgcagatg aacaagctat
    11701 cgttcactac atgtataatt ctggcgataa aatgacaaca gcaaaggcga ttgagttgac
    11761 agggagaagt cgttcgtttg ttgtcaaaat gctacatcat cttcgtgatt tagaaatcat
    11821 cacttggttt ggttcaagta aaaatgaccg taatcaatat tatcttttag ttgataaatg
    11881 attgcagcca ggatacttat tagtaataag aatacagtag aatacagaaa aagtggtgtt
    11941 ccataaaata ttgatcacca cttttgatta tagaagttta aataaagtgg atatttgtat
    12001 atag
//
LOCUS       DARYMD010000058        11388 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYMD010000058 DARYMD010000000
VERSION     DARYMD010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11388
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(72..2753)
                     /locus_tag="TU818_001646"
     CDS             complement(72..2753)
                     /locus_tag="TU818_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL0924441.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGDIRPITEADKQTILATNKDLAKQALRVLMMAYKYTEVIPVLETEV
                     VEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVVLVELVKAIQRSLGQDDKAI"
     gene            complement(3101..3487)
                     /locus_tag="TU818_001647"
     CDS             complement(3101..3487)
                     /locus_tag="TU818_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL0924442.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNNNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKALIAIPTPVGIQQFLTDTSHFHLDHGQQT
                     VTLDYALLQPSTETAFAHYHLEIKWY"
     gene            3568..4869
                     /locus_tag="TU818_001648"
     CDS             3568..4869
                     /locus_tag="TU818_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL0924443.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSENHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     SVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            5094..5903
                     /gene="yidA"
                     /locus_tag="TU818_001649"
     CDS             5094..5903
                     /gene="yidA"
                     /locus_tag="TU818_001649"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL0924444.1"
                     /translation="MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATG
                     RPITGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPN
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            5903..7117
                     /locus_tag="TU818_001650"
     CDS             5903..7117
                     /locus_tag="TU818_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL0924445.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     MIKYDPSLFISQALIGEERKDNDFTLSIIDFLKTIGVEWTGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            7117..8352
                     /locus_tag="TU818_001651"
     CDS             7117..8352
                     /locus_tag="TU818_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL0924446.1"
                     /translation="MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKNIKIAAILYSIPMTGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKKPKSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(8561..9319)
                     /locus_tag="TU818_001652"
     CDS             complement(8561..9319)
                     /locus_tag="TU818_001652"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL0924447.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVKAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLADMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIICCGESLETYEAGKAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TU818_001653"
     CDS             complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TU818_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL0924448.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
BASE COUNT         3417 a         2582 c         2261 g         3128 t
ORIGIN      
        1 ttatttttta actatgaacg tcagaccttt ttgttagttt gaaagtgttc ttatcttttt
       61 gctaatgacg cttaaatcgc tttgtcatct tgaccaagtg agcgctgaat agccttgaca
      121 agctcaacaa gcacaaccat caagagactt ccaacaataa caactagcca ttgtgtaagg
      181 gtcaaatgag tcacatgaaa gaatttgtta aagccaggga caacaactgt agccatcaag
      241 gcaacaaagg ctactgggat agaatagtta aataatttat tcttaaataa tccaactgta
      301 aagatagact gataaacgga cttaacatta taagcatgca ccagctgaat gagaccaagt
      361 gttacataag ccatcgttaa agcatcggca tgcacgtcat ggtagcttgt atgctctggg
      421 aacatcaagg caaagccata aacaccaagc actaggattg tctgaagggc accctgatac
      481 agaatagctt cttttacacc accgtcaaag aagcttgatt ggcgtccacg aggcttgtgc
      541 ttcatgacac caggctcagc aggctcaaca ccaagagcga tcgctggcag cgtatctgtt
      601 accagattaa tccaaagcag gtgaaccggc tgaagcacgt cccagccaaa taaggtagca
      661 agaaagatcg taaagacctc agccatgttg gcagaaagca ggtactgaat tgttttttga
      721 atgtttgaaa agaccttacg tccttcttca acggcaacaa taatagttgc aaagttatca
      781 tcggcaagga ccatatcaga agctccctta gaaacctctg tacctgtaat ccccatacca
      841 ataccaatat cagctgtttt aagagacggc gcatcattga caccatcacc agtcatagca
      901 acaaccttac cttcattttg ccaagcctta acgatacgaa ccttatgctc tggagataca
      961 cgcgcataaa cagaatattg tctaaagacc ttttggaagg cttcgtcaga cagctcattg
     1021 agctcagcac ccgtaaagac atggtcaaca ccatcttctt cgataatgcc aagacgcttg
     1081 gcaatagctt ccgctgtatc ctggtggtca ccagtaatca tgatcggacg aataccagcc
     1141 tccttagcca ccttaacagc ctgagccgct tcagggcgct ctgggtcaat catgccaaca
     1201 agccctgaga aaatcagctc tgcttcgacc acctctgttt caagtactgg aatcacttct
     1261 gtgtatttgt aagccatcat caagacacga agggcttgct tagccaagtc cttattagta
     1321 gccagaatcg tttgcttatc agcctctgta atcggacgaa tatctccatt ttcttcaatt
     1381 tgagtgacac gttttaacag ctggtcagga gcacccttaa cagcgatgaa gtatctgcca
     1441 tcagcttgct tgtgaatggt tgacatcagc ttacggtcag aatcaaatgg taattctgcc
     1501 acacgaggtt ctgaaacaag agcctcacgc acatcaaagc gatgatctaa gccaaattgc
     1561 accaaggcag tctctgtagg atcaccaatc agcttacctg ctggatcaac cttagtatca
     1621 ttggcaaaat tcatcacacg aagggtattg ttgtcaaagg caatatcagc tgatgactct
     1681 tgaagtgccc cgttagtata aaccttttca actgtcatct ggttcatggt caaggtacca
     1741 gttttatctg aggcgataat ttcagttgaa ccaagggttt cgaccgcagg caatttacgg
     1801 ataatagcgt tacgctttgc tagcacctgt gttccaagag aaagcacaac cgtaacaata
     1861 gctggaagcc cctctggaat ggcagcaacc gcaagcgcca ctgatgtcat caagccttca
     1921 agtgggcgct gaccacgtaa aaagacacca actgcaaagg tcacagctgc aatcacaaga
     1981 atagcatagg ttaaaatctt agatagattg tcaaggtttt gctttagcgg tgtgtctgtc
     2041 tcatcagcat tagccagcat gccagcgata tggcctacct cagtgtacat accggtgttt
     2101 gtgacaaccc ccataccgcg tccataggta acgtttgagt tttggtagcc catgttaaca
     2161 cgatcaccaa taccagcatc agcagaaacc tctcttgaca ggtccttttc aactggaact
     2221 gactcaccag taagagcagc ttcctcaatt tttaaggaat tgacctctaa caaacgcata
     2281 tcagctggca ccacatctcc tgcctctagc aggacaatgt cgccagggac aagctcttta
     2341 gagtcaacct caatcacatg accatcacga cgcacacgtg ctaagggact agacatggat
     2401 tttaaggcct caatcgctgc ctctgcctgc ccttcctgat aaaccccgaa ggctgcattt
     2461 aagataacaa cagctaaaat aatgatggca tctgtcaagc cctccatccc ttctgttacc
     2521 acagaaagaa aggccgctgc aaccaaaata ataatcatca aatccttaaa ctgatcaagg
     2581 aatttcatga acaggctgcg cttttcaccc tcgtcaagct cattacgccc ataagctgct
     2641 aggcgctgct gtgcctctgt actcgttagc cccttacgac tagactctaa ttgagctaat
     2701 actgtttctt cactttgcgt atagaacgct tcatgtcttt gttctttcga caaattggtc
     2761 cctccttggt ctttttatgc tttattcaac taaaaagacc tgtttatttt tcttaaacaa
     2821 gtctcgctgt ttcagattgt accggaaatc gaaattccgt attgacgaca caatcacggc
     2881 taaccgtctg ctactccctt gatatagtca ctattataat aaaatgatga ccaaaaaaca
     2941 agaaaaaaac aaggaaatat tttttaaaag ccccaaatca tctgatgatt ttcagagcaa
     3001 aggtaactga tgaccaagct tagactatca ttaccgagat acagacagca gacacaggct
     3061 gtcatcttag gagactaaca aaggacttcc tctgctgaga tcaataccac ttgatctcca
     3121 aatgataatg agcaaaggcc gtctcagtgc tgggctgtaa taaagcataa tctagggtca
     3181 ctgtctgctg gccatgatcc aagtgaaaat ggctcgtatc tgtcaaaaat tgctggatcc
     3241 ctacaggcgt cggaatagcg atcaaggctt ttttgttagc aagaaacctc atcacagact
     3301 gaggctttga aaagcgactc atcgttagct cagcagcatt gaacttaatc actacccttt
     3361 cgttgttatt attttgataa attagatagg tagcatctgc cttttgtctc aaatccccag
     3421 tatgaatctc cttgattagc tctgtttcct gaccatagct gatcttgtta ttaatttcaa
     3481 tcttcatgat atcttctttc tcttgagttt tgctcgtcta ttctaccaat ttctgaccat
     3541 tttcgcaatt tctgctataa tagaagcatg aatgaaaaag tatttcgtga ccctgttcac
     3601 aactatatcc acgttaatca tcagctcatt tacgagctaa tcaataccaa ggaatttcaa
     3661 cgactaaggc gaattaagca ggtgccaaca acagccttta cctttcatgg tgccgagcat
     3721 agccgctttt cacactgtct tggtgtctat gagattgctc gccgtgtcac agagattttt
     3781 gaagaaaagt atgcagacct ttggcataag gaggagagtc ttgtaaccat gactgctgcg
     3841 ctcctgcatg atattggcca tggtgcttac tcgcacacct ttgagaccct atttgatact
     3901 gatcacgaag ctgttactca agatatcatt accagtccag aaacggaaat taatgcgatt
     3961 ttgacgcgct actctcctga ttttcctgac aaggtagcta gtgttatcaa ccacacttac
     4021 cccaataaac aggtagtgca gctgatctct agtcaaatcg actgcgatcg catggattat
     4081 ctgctgcgcg actcttactt ttctgcggct aattatgggc aatttgacct aatgcgcatt
     4141 cttagggtta ttcgacctgt gaaagatggc atagcttttg atctcagcgg tatgcatgcc
     4201 gtagaggatt acattgtcag ccgctttcaa atgtatatgc aggtttattt tcaccctgcc
     4261 agtcgagccg tcgagctgat cctacaaaac ttgctgaagc gtgctaaggc tctctatcct
     4321 agccagcagg actatttcca aaagacagcc cctggtctca ttccattttt tgaaaaaagt
     4381 ttcacgcttg ctgattatct ttgcttagat gatggtgtgc tcaataccta tttccagcaa
     4441 tggattacta gtgagaacca tatcctgtca gacctgtcta gtcggtttat caatcgaaaa
     4501 attttaaaat ctgtcacctt tgaccaagaa tcacaacagg atttagagcg cttgcgaaag
     4561 cttgttgagt cagttggttt tgatcctgat tattatacag gtatccatgt caattttgac
     4621 cttccttatg atatttaccg tcctgagctg gaaaatccaa gaacccaaat tgaaatgatt
     4681 caaaaagatg gcagcagggc tgagctatcc cagctctctg cgattgtcaa agctctcaca
     4741 ggcacaagct atggtgatag acgcttttat ttcccaaagg aaatgttaga gcttgatgac
     4801 ctctttacat cagataagga agcctttatc agctatatct ctaacggaca ctttcatttt
     4861 aacaactaag gaccagccaa ggtccttttg gctttttcat cacgctctag atttaaaatg
     4921 gtatattacc cgataaggac agctagagct ctgacaagca caagccacca aacacagcag
     4981 agcctttaat attgccaaaa tctcttttgt tttcatgaca aaagaaccta tttttagtaa
     5041 gatagaaggt ggcaaatcat tgattacaaa tcagaacaac caaggagaat tccatgtcta
     5101 tcaaacttgt tgccattgat attgatggca ccttactcac tgacgatcga cgcgttacta
     5161 atgacgtttt tgatgccata caggaggcca aggcccaagg agtgcatatc gtcattgcta
     5221 cgggacgtcc cattactggg gtcatctcat tattagagca attgcaatta aatcaaaagg
     5281 gagatcatgt catcaccttc aatggtggac tgattcagga cactgcaacc ggtgaagagg
     5341 tggttaaaga gctgatgacc tacgatgatt acctcgacat agaatattta agccgcaggc
     5401 taggcgttca catgcatgcc atcacaacag agggcatcta tactgctaac cgaaatatcg
     5461 gcaaatacac tgtacgagaa gcaaggcttg tggacatgcc tgttttttat cgaacacctg
     5521 aggagatggc tgacaaagag atcgtcaaaa tgatgatgat tgatgagcca aaccttttag
     5581 atgaggccat caaacagatt cctcaagcct tctatgacac ctacaatatt gtcaaatcaa
     5641 caccttttta tctcgaatta acaccaaaaa ctgtcagcaa gggcactgct attggtcacc
     5701 ttgccaaaaa gcttggcatt gacatgtccc aaacgatggc aatcggcgat gctgaaaacg
     5761 atcgagccat gcttgaagcg gttgctaacc ctgttgtcat ggaaaatggg gctcccgagc
     5821 tgaaaaagct ggccaaatac atcaccaaat caaacaatga cagcggcgta gcgcatgcta
     5881 ttcggaagtg ggtattaaac taatgtatac atataaaatc ggaatttcag ctaaagagca
     5941 cgatcagttt gtcctatcac atcctcaggt caatctgctg caaagcgctc attgggctca
     6001 ggtaaaggat aactgggagc atgagctcat tggtttttac caggatgaca agcaagtcgc
     6061 tgctgctgct tgccttatca agagactccc cctaggcatg accatgattt acattcctcg
     6121 agggccgatt atggattatt ctgactttga gttggttaac ttcgtcatga ctagcctaaa
     6181 ggcttatggt aaatccaagc gagctctcat gattaaatac gatccttcct tgtttatcag
     6241 tcaggcctta ataggtgaag aaagaaagga caatgacttc accctctcca ttattgattt
     6301 tttaaagacc atcggtgttg aatggactgg caggaccaag gagcttgagc aaacgattca
     6361 gccccgcttt caggccaaca tttacgccaa ggactttaag ctccaaagct tatcaaaaaa
     6421 agccagacag tctatccgaa ctgctcaaaa taagggagtc gagattatta ttggctcaac
     6481 agagctactt gaagacttct cagcactgat gaaaaagact gaggagcgaa aacacatttc
     6541 tttgcgtggc atttcctatt atgacaaatt aatgaccact tacgctaatc aggcttacat
     6601 taccatggct agattgaacc ttcccaagca aaaagcgctc atacagcagc aattagagga
     6661 agccttgagc aatcagcagg cctttaccca gcacagtaag ccaggtaagg tcgcagaaaa
     6721 ccaaaatacc attaaaaggc ttgaaaagga attggctttt ctagataagg aaatacaagc
     6781 aggtaaaagc cttgtacctc tagcagctac cctgacactg atctatggac agacctctga
     6841 aaacctatac gcaggtatgg ataatgactt tcgccaatat caggcagccc tcttaacctg
     6901 gtatcatacc gcagaagagg cctttaagcg cggttgtcaa tggcacaatt tagggggcgt
     6961 tgaaaaccaa ttagatggtg ggctgtttca gtttaaagca agactaaacc cagctatcga
     7021 agaatttgca ggagaattca gcattccagt tggacctatc tcaaaggtgg ccatgatagc
     7081 ctacaatttg agaaaaaaac taaggagtaa cccttaatgg ctttagatat cattgacaaa
     7141 gaaacgtttg gctcattttg cagtcaaatg aagtataaat ccttcattca atctatagaa
     7201 atggcagagc tgctgcaaaa gcgtggttat cagacacaat accttgcaat cagtgaccag
     7261 aaaaacatta agattgcagc cattctctac agtataccaa tgaccggcgg cttacgcatg
     7321 gaaatcaact caggtccagt agtggctgat acgacctaca caacagcctt ttacaaagcc
     7381 ttacaggact atgccaagca gcagggagca cttgagctag tcatcaagcc ctacgatacc
     7441 tatcagacct ttaccagcga tggtcaccca aacgatgatg aaaagccaga gctgatcaag
     7501 accttgacag agctcaattt tacacatgat ggcctgctaa caggctacca taatggtgaa
     7561 ggagattggc attatgttaa agatttaagc ggattgacct ctgctaatgt catcaattcc
     7621 ttcagtaaaa agggcaaggc cctgctaaaa aaagccaaaa cctttggcat taagctacat
     7681 aagctcaatc gtgatgagct aacacaattc aaggaaatta ctgctgctac atctagtcga
     7741 agagattata ccgacaagtc tttatcttat tatcaggatt tctatgatag ctttggggat
     7801 agctgtgaat ttatggttgc aaccctcaat tttgatgact acctgaccaa tctagagcac
     7861 agtcaagaca agctaaagca gcgcattagc aaattagagg cagacctagt taaaaaacca
     7921 aaatcagaaa aaaaacaaaa tcaactacgg gaactctcca gccaatttga tacctttcaa
     7981 gttcggatag ctgaagcaca ggagttaatt gtcaagtatg gcaaaaagga cattcctcta
     8041 gctggtagtc tctttgttta caccccgcag gaggctgtct atctcttttc tggctcctat
     8101 ccagaattta acaggttcta cgcgccagcc ctattacagg aacatgtcat gctaagagcg
     8161 attgaaaaga aaatcagctg ctataatttt cttggtatca tgggcgaatt tgatggctct
     8221 gatggtgttt tacgctttaa gcaaaacttt aacggctata tcacacgaaa gatgggaacc
     8281 tttaggtatt atccaaagcc cttcaagtac aaagccatac aggccatcaa gacaatgctt
     8341 ggtcgcagct aagtcaagct agtggctaag cagcccttta agccttccaa tggctattga
     8401 ccacaataat aaatccttga ttgtcttact cagaacccct ttagtaaact ttccaaccta
     8461 aaaataaggt ataggtgatc ccatgctcaa gaaggctatc aagcaaacca aaagctcaag
     8521 gaattaaccc ttgagctttt tagctatatt ataattgtca ttagttgaca aaatcaagca
     8581 aggcaaggaa gctatctgct tctagtgatg caccaccgac aagagctccg tcaacatccg
     8641 gacaagccat gtactcctta atgttttcag gcttcacaga accaccatac tgtacacgaa
     8701 ccttgtctgc cacctcttga ccaaagtcag cagcaaccac atcgcgaaca gccttacaca
     8761 tgctttgagc atcttcttga gtggcagatt taccagtacc gatagcccag attggctcat
     8821 atgccaatac caatgaagca acctgctcag cagatagccc ctctagagcc gcagacacct
     8881 gtgcaccaac aaaggctact gccttgccag cctcataggt ctcaagagac tcaccgcagc
     8941 agataattgg tgttaagcca ttagcaaaga tggcttttgc ttttttatta atatcttcgt
     9001 ctgtttcgtg gaagtaatca cgacgctcag agtgaccaat caccacataa tcagctccca
     9061 tgtcagcaag aaccttagga gaggtttcgc ctgtataagc gcctgaattt tcaaaataac
     9121 agttttgcgc agcaacctta aggacagagt ccttagcagc ctcaattgta gtgaccaagt
     9181 caacagctgg tgctgctact gcaacgtcaa caagatcgtt tgaaggtaat ttgcttacta
     9241 ctgccttaac aaaggctttt gcctcttgag gatttttgtt cattttccag ttaccggcaa
     9301 taattggttt acgtgacatt tcacatacct cttctttttt tatttacatc tactattcta
     9361 gcacaatttc tatgctaata aaagaaaatg gctgactttt aggaatattt tcacaaagaa
     9421 aagagtattt tctgaaacca ttttcaaacg ataaggctta tcgattagct aagcagaccc
     9481 gctaagtcct catctttata aacagagcaa aaagagccct taaaacaagg gctctcacaa
     9541 ttaagctgtc tgactttaat cgttatctgg gaacttaatc aaaattaagc ttcgatttct
     9601 gaaacgatac ctgaaccaac agtacgtcca ccttcacgaa ttgagaatgt agtaccttgt
     9661 tctacggcga ttgggtggat caactcaacg tcaatagtca cgttatcacc aggcataacc
     9721 atttctgtac ctgctggaag ctcgattgaa cctgttacgt cagtagtacg gaagtagaat
     9781 tgtggacgat agttgttgaa gaatggtgtg tgacgtccac cttcttcttt agtaaggata
     9841 tatacttcac ctttaaattt agtgtgtggg ttgatagaac ctggcttagc aataacttga
     9901 ccacgttcga tttcatcacg ttgtacacca cgaagaagaa caccaacgtt gtcccctgca
     9961 agaccttcgt caagctgttt acggaacatt tcgacaccag taacaactgc ttttttgatc
    10021 tcgtctctga taccaacgat ttcgatttcg tcgttaacac gaacagtacc gcggtcgata
    10081 cgtcctgaag caacagtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
    10141 aatggcttgt ctgtgtcacg ttctggttct ggaatgtatg aatcaacagt atccatcaat
    10201 tccatgatga tatcttcgta tttgctgtcg ccttcaagag ccttaagcgc tgaaccttgg
    10261 ataactggaa ggtcatcacc tgggaaatca tattctgaaa gaaggtcacg aatttccatt
    10321 tcaacaagct caagcaattc ttcatcgtca acaaggtcaa ccttgttcat gaacacgata
    10381 aggtgcttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
    10441 ccgtcagttg aagcaactac aaggatagct ccgtccattt gagcggcacc agtgatcatg
    10501 tttttaacgt agtccgcgtg tcctggtgcg tcgatgtgcg catagtgacg tgtagcagtt
    10561 tcgtactcaa cgtgtgcagt gttgatagtg attccgcgtt cgcgttcttc tggagcagca
    10621 tcgattgaag cgtagtcttt tggttggtta actgagcttg gtagacgacg tgcaagaaca
    10681 gttgtgattg cagctgttaa agtagtttta ccatggtcaa cgtgtccaat tgtaccaatg
    10741 ttaacgtggg gtttactacg atcgtatttt tcttttgcca ttttaggaaa agcctccaat
    10801 aaaatatatt ttatagatag acggtaggca atacagtcta actttacctt actattgtag
    10861 caaattataa ggaaattgca agcagtaagt gaggaacttt aacggattta tcgttatccc
    10921 tgatttcaac aaccctagca tacaaaaaag gaaagagttt tcgtcttctc ccaggcaatc
    10981 cgctctttac cgttttttgc ttttcaaggc tctaggcatt tgcatacttt tggaggagag
    11041 ttgaattgtt aagagataat gcattcggag atctataaat cataggcagg acataccgat
    11101 ccaaaactaa gatagtggag acttgatggt ccatgacaga cgcgcgaaac agctatttcc
    11161 gaatgataat atagatgaga gtagacactt tcaacgttct tcctatagta aaagctatgc
    11221 aaaatcctac atattcttga aatagctgaa cattgaaata caggaagctt tattttattg
    11281 ctaaaaatct ttcatgtgtc tatcgtggtc gatgatcgca gagttagctt gttaatattt
    11341 tctatctttt ttattatatt ttgttaattt tataatctat ttaactat
//
LOCUS       DARYMD010000059        11288 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYMD010000059 DARYMD010000000
VERSION     DARYMD010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11288
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            160..747
                     /locus_tag="TU818_001654"
     CDS             160..747
                     /locus_tag="TU818_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924449.1"
                     /translation="MIDKIKNILFDVRLSANKIENEIIFYNGFPEDSVSLSFAGNKCI
                     IEEIHRDNRIRLMETTSEYHAILYCVAILDQIFNTSKNIKITREIKEYIQEGNIIAAE
                     QLLSEKLDPTLFSLGSVEKDKLTLVKENNAYSLIFNDVQILTDLSSLRAYIVLFNYTK
                     KLERAKELYARALHDLPDCKLEFNQFVEYYLIGRN"
     gene            1183..1602
                     /locus_tag="TU818_001655"
     CDS             1183..1602
                     /locus_tag="TU818_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL0924450.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYYKYELVMDLTKKNIVNAYYQSEEIIRKQISVEMKKWNLSFDDLAN
                     IQKGEITKVFGQGGGIQIKFPTGVGIYKKMGLLKEIN"
     gene            1603..1926
                     /locus_tag="TU818_001656"
     CDS             1603..1926
                     /locus_tag="TU818_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924451.1"
                     /translation="MDNTNILNWKKDIEEAIKNRGFESLHYVLFDEEKRLPWAFHLYQ
                     KNGKFYVEGRDERSYIIGHSREYRKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPS
                     PLWNE"
     gene            2185..2814
                     /locus_tag="TU818_001657"
     CDS             2185..2814
                     /locus_tag="TU818_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924452.1"
                     /translation="MTTLAGMSPEDSQRYIQWHKYAKAGLSPSDRVRILEISEKAPKI
                     EYLPGKTSDSILAISKGDRPNVEKVYSPDYIGFHRKQFDNGATRFQKFKPNVDYQDGL
                     VGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYRLDVSPEVVSQ
                     KGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAVN"
     gene            2796..3218
                     /locus_tag="TU818_001658"
     CDS             2796..3218
                     /locus_tag="TU818_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924453.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKQSHRKFVIDTPTALIADP
                     TSVSLFSEEELSKLVPIAEQQWIDWKGKLPDDYVSPLK"
     gene            3477..3881
                     /locus_tag="TU818_001659"
     CDS             3477..3881
                     /locus_tag="TU818_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924454.1"
                     /translation="MSKNYTEADVAKLTELTTHNAKTKTALLGYYEANSVTSYEQIAH
                     QNKLTYFDAGSDGWNAMSRVDSKLAQRVNREFLIKQIEKRKTFILTSNPYTAQSIADV
                     SGIGKSYAKEIQILAENGYNIEKFERFWRAYK"
     gene            3878..4306
                     /locus_tag="TU818_001660"
     CDS             3878..4306
                     /locus_tag="TU818_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924455.1"
                     /translation="MSEEQYLPVKESLGYRNLKIALMNVFSIDLDKFTIIEGEFENFG
                     FHLNYNNKEIIIWITSTGKNRQFEYGEGGQLMISLPNPKYPDRSFLDRVTLESLLTDT
                     EKIEAVDYAFGRYEHRLEIALAILKDYLDSDEAKVLLKNE"
     gene            4299..4712
                     /locus_tag="TU818_001661"
     CDS             4299..4712
                     /locus_tag="TU818_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924456.1"
                     /translation="MSEQYLSIKESLGYKNVKQALWTIFSANLDEISIHEGEDENFNF
                     VFTYKNCEMMMGIYDTGKNIQFQAGEGGLFSVSLPNPKYPEQSFQKIVSLSYLISDKN
                     VSENIRWCLGLDLKSVEYVMRVLKDYLDQKCEEEQ"
     gene            4975..5367
                     /locus_tag="TU818_001662"
     CDS             4975..5367
                     /locus_tag="TU818_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623140.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL0924457.1"
                     /translation="MTPAFLKTGDLLDRYGESGGTFTSPIVDRKVIPFNKRGLPYPED
                     YQNYHQYKVLKDINMENVEKGYHNLSDSRKKELNLLMNRFDFSLVDIATPQKGMIDLV
                     FGSGGGIQIKLGTSVSWYEKLGLIKEIK"
     gene            5368..5691
                     /locus_tag="TU818_001663"
     CDS             5368..5691
                     /locus_tag="TU818_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924458.1"
                     /translation="MKNLDHQKAELLEAVHQLGYDSLRYSIFSKERPGEWETVIEYDN
                     SQGLYVVYATMDRASYNKKLTFETFQEAKEKFLEKLRLDIQINRYYVEEGMPVNYDSP
                     LWSKN"
     gene            6004..6474
                     /locus_tag="TU818_001664"
     CDS             6004..6474
                     /locus_tag="TU818_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL0924459.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKI
                     RAWMYRVAVRKYIDRYRRDKAYLDILQRDFFHQERVVEFDHPNYEPLYTAVNELPEKY
                     RWVLSFYYFQDLSVKEMASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFN"
     gene            6458..7551
                     /locus_tag="TU818_001665"
                     /pseudo
     CDS             6458..7551
                     /locus_tag="TU818_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
     gene            complement(7845..10991)
                     /locus_tag="TU818_001666"
     CDS             complement(7845..10991)
                     /locus_tag="TU818_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924460.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDTSDGIAATVNAGDT
                     AAPSAEAKLSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATDSTEPEKEQILSLLDKAASLLQQFTLQGLGNGIFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNEKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDDSNRTLRFLGLGNAEYATLKVDYNAS
                     TLTLKTKKAKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQALTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYETSHQGIQLKMAIAVALEFNKPVGAWYNESRKIDPLERF
                     ATFAEAEQGNILFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDIT
                     KGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKS
                     ALKDYPVIINNLEKDTKQ"
BASE COUNT         3575 a         1888 c         2424 g         3401 t
ORIGIN      
        1 tcagaggata ctatgtttat ttgagtatat gctggtgagg tttcagatca atttgtgaag
       61 tataaaccta atggagttga taaatatagt attcaagagc taatggatat ggttttttag
      121 atgacataac tgatttggtg aagaaaggag aaattagaat tgattgataa aataaaaaac
      181 attctttttg atgttaggct gagcgcaaat aaaatagaaa atgaaataat attttataat
      241 ggctttcctg aagatagtgt atctttatca tttgcgggta ataaatgtat cattgaagaa
      301 attcatagag ataatagaat caggttaatg gaaacaactt cagaatatca tgctatttta
      361 tattgtgttg caattttgga ccagatcttt aatactagta aaaatatcaa gattacaaga
      421 gaaatcaaag agtatataca ggaaggaaat attatagcag ctgagcagtt gctctcagaa
      481 aaattggatc ctactctttt ttcattaggg tctgtggaaa aagataaatt aacccttgta
      541 aaagaaaata atgcctatag tttaatattt aatgatgtgc aaattctaac tgatttaagt
      601 tcattacgtg cttacattgt tttatttaat tacactaaaa aacttgagag agcaaaagaa
      661 ttatatgcta gagcactaca tgacttgcct gattgtaagt tagaatttaa tcagtttgta
      721 gaatattatt tgataggaag gaattaataa aagaactatt gaaataccat atggcatttt
      781 gagttcagat gcccagtcat ggcaggaggc agcgaacaag atgctcagcg agctacatta
      841 gtaggcaata tcctaggagg attcgccgcc tcaagcgtcg ccagacggtt cagcttgaat
      901 gagccaatag cagctagggt gacgaaaccg acctacagcc gccggcagct tttgaagaac
      961 cttgagaaca gcaggctggc aagagaaagc tcgaggtttg atgattatct tcgaagagaa
     1021 taccggttaa agggaaggta ttttgcagaa agaaccacta tttcaaatgg aaagataggt
     1081 tatctttcat ctgactattt tgaaggcaag caaattccgg ttcgctctag agcttttgtt
     1141 gacgaagcag gccatattaa atggccaaat gccgatggct ttatggtgga taatttaggt
     1201 aatcctataa cggagcaggt cactctcaaa gcaggtcaaa tcattgatcg atatggatca
     1261 agtagtggtc gatttaccag tccgatagaa aatggggtga cattaccatt taataaacgt
     1321 ggattaccct acccagaagg atatcaagac tattataagt acgaattagt aatggatttg
     1381 acgaagaaaa atattgttaa tgcgtattat caatctgaag agattataag aaaacaaata
     1441 tctgtagaaa tgaaaaaatg gaatctttcc tttgatgatt tagctaatat tcagaagggt
     1501 gagattacca aagtatttgg gcaaggtgga ggaattcaga ttaaatttcc gacaggtgtt
     1561 ggtatttaca agaaaatggg tttattaaag gagattaact agatggataa tacaaatata
     1621 ttgaattgga aaaaagatat tgaagaagca attaaaaatc gaggttttga gagtttacat
     1681 tatgttttat ttgatgaaga aaagcgactt ccttgggcat ttcatcttta tcaaaaaaat
     1741 ggaaaattct atgttgaagg aagagatgag cgatcatata tcattggtca tagcagggaa
     1801 tatcgtaaat ttgatgatgc caagcatgaa ttgcttaaaa aattagaatt agttatagaa
     1861 tctaatcggt taaaaaagca gttaggtgaa cctacagaat atccctcacc actatggaat
     1921 gaatgagttt catgtattgt atgccatggc accaagcttt taggaggcag cgagcaagac
     1981 gcccaaagag caacattagt tgggaatatc ctaggaggac ttgccgcctc aagcgccgct
     2041 agaaggttca gcttgaatga gccaatagca actagggtga cgaaaccgac ccacaaccgc
     2101 cagcagcttt tgaagaacct tgagaacagc agactggcaa gagaaagctc aaggtttaag
     2161 aattatgtag caagagaaaa attcatgaca acccttgcag gcatgagtcc tgaggatagt
     2221 cagcgctata ttcaatggca caaatacgca aaggctggac ttagtccgtc agatcgagta
     2281 aggattctag aaatatctga gaaggcaccg aagatagagt atcttccggg aaaaacatca
     2341 gatagtatat tggcaatatc caagggtgat cgtccaaatg tggagaaagt ctacagtcca
     2401 gattatattg gatttcatag aaaacaattt gataacggtg caactagatt tcagaaattt
     2461 aagcccaatg tagattacca agacggttta gttggtgacg atttaggcaa tagtttttgg
     2521 ttaagtacca aggacgcgga tattatccag gagataggaa agggaaataa ccgtctttat
     2581 gagacactct taggctttga tgaagggtat ttagaagatg gtcccctcta tcgcttagat
     2641 gtttcaccag aagttgtttc acaaaaaggt gtttcaatac caagtggtaa tgaaaaaggg
     2701 gcaaatagct ggtggcgtcc tggaggtcgt acttatccgg ggaatatacc agagggagtt
     2761 atgcaaggta tcagtacaaa gaaaggagat cacacatggc acgcagtcaa ttagagtggg
     2821 aagatgttag tcaatatgag gaggtaaagg gctatggtca aagggtgtgg aagcatcaag
     2881 ggaaatatta ctttgttgcc gaagaaggtg gcattgctgt tcaacgagta gtatatgagt
     2941 taccgtatga cttatttgaa ttgttggaaa gtggagaacg tagtcttgga gatgttcatt
     3001 caaagctaca agatggtaat tggccaccaa cagaagagga aaagaagcaa agtcatagaa
     3061 aatttgttat tgacacacca actgcgctga ttgcagaccc tactagtgtg tctctgttct
     3121 cagaagaaga attatcaaaa ttagtgccaa tcgctgaaca acagtggata gattggaagg
     3181 gaaagctgcc agatgattat gtcagtcctt tgaaataatg tttaagatag cggagccgag
     3241 attagctctg ctattttaaa gcatgttctt aataattagc ctgcgacagc ttatcaggga
     3301 gtagctcgtc accttgaagc caatgccaag cgtctccaag cgccgccaga aggttcagct
     3361 tgaatgagcc gatagcagct aaagtgacga aatcagcgaa aataaccctt tctgaaaagg
     3421 tactagacac aaaggttcgg tttgatgagt ctcgcattgt ggcttacgca gaaagtatga
     3481 gtaagaacta tacagaagct gacgtggcca aattaaccga gctgaccacc cacaatgcaa
     3541 aaaccaaaac agctttgctg ggatattacg aagcaaacag cgttacttcg tatgaacaaa
     3601 ttgcacatca aaataagtta acttactttg atgccggaag tgatggttgg aatgcgatgt
     3661 cgagagtgga ttctaagcta gctcaaaggg ttaatcgtga atttttgata aaacaaattg
     3721 agaaaagaaa aacatttata ttaacgtcta atccatatac tgctcaatca atcgcagatg
     3781 ttagtggtat cgggaagtct tatgctaaag aaattcagat tttagcagaa aatggatata
     3841 atattgaaaa atttgaaagg ttttggaggg catataaatg agtgaagaac agtatttacc
     3901 agtaaaggaa agcttaggat atcgtaactt aaaaatagct ttaatgaatg ttttttcaat
     3961 agatttggat aagtttacaa ttattgaagg agaatttgaa aattttggtt ttcatttaaa
     4021 ttataacaat aaagaaatca taatctggat tacatcaact ggtaagaata gacaatttga
     4081 atatggagaa ggaggacaat tgatgatttc acttcctaat ccaaagtatc ctgatagatc
     4141 ctttcttgat agggtaacct tagaaagtct tttaacagac accgaaaaaa tagaagcagt
     4201 tgactatgct tttggaagat acgagcatcg tctcgaaata gcgttggcca ttctaaaaga
     4261 ttatttagat tcagacgaag caaaggtttt attgaaaaat gagtgagcaa tatttatcaa
     4321 taaaagaaag cttaggttat aagaacgtta aacaggcttt atggactatt ttttcagcca
     4381 accttgatga aatttctata catgaaggag aagatgagaa ttttaacttt gtctttacat
     4441 ataaaaattg tgaaatgatg atgggaattt atgatactgg taagaatatt caattccaag
     4501 ctggagaagg tggtttattc agtgtaagtt tacctaatcc taaatatccg gagcagtcat
     4561 ttcaaaaaat tgtatcactt tcttatttaa tttctgataa aaatgtaagt gaaaatataa
     4621 gatggtgctt aggactggat ctgaaatctg ttgaatatgt tatgcgtgtt ttgaaggatt
     4681 atctggatca aaaatgtgaa gaggaacaat aattctaatc acttctggag ggcatataga
     4741 tgagtgaaga acagtattta ccaatacctt cgaagagaat accagttaaa gggaaggtat
     4801 tttgcagaaa gaatcaccat gccagatgga aaatatgctt atctgtccaa tgacattgat
     4861 aaagctaccg gaacaccaat tcctgtccga tatagaaatt accttaaggc tgatggttct
     4921 attaattggc caaactataa tggctttagt cttgatgtaa agggaaggcc tatcatgact
     4981 ccagctttcc taaaaacagg tgatttactt gatagatatg gagaatctgg aggaacattc
     5041 acaagtccaa tcgttgaccg taaggttata ccatttaaca agcgaggctt accataccca
     5101 gaggactatc aaaattatca tcaatataag gttcttaagg atattaatat ggaaaatgtt
     5161 gaaaagggtt accataattt atctgatagt agaaaaaaag agttaaatct attaatgaat
     5221 agatttgatt tttcactggt agacatagca actccacaaa aaggaatgat tgatcttgtc
     5281 tttggctctg gtggaggtat ccaaataaag ttaggaactt ctgtaagttg gtatgaaaaa
     5341 ttgggtttaa ttaaggagat aaagtagatg aaaaatttag atcatcaaaa ggcagaacta
     5401 ttagaagcag tccatcaatt aggttatgat agtctaaggt attccatttt ttctaaagag
     5461 agaccaggag aatgggaaac tgtcattgaa tatgataata gtcaaggctt atatgttgtg
     5521 tatgcaacta tggatagagc tagttataat aagaaattaa catttgaaac atttcaagag
     5581 gctaaagaaa aatttcttga aaaacttcgg ttagatatcc aaatcaacag gtactatgtg
     5641 gaagagggca tgcctgtaaa ttacgattct cctttgtggt caaaaaatta atacaagtaa
     5701 aggagaatat acatggcatg tagtcaatta gagtgggaag ataaatgaaa taatggtcct
     5761 aggaaatgtc ccgactggaa actatcttat gaactctttt atggaaaagt gttgcactta
     5821 atttgaattt tgtcatataa aaaagcccta taatctccat ggtggactta cccactacag
     5881 aaatgataga gctaaaaatc tccatttggg gatttttttg taaccaaatg aagcagtcgt
     5941 tcgttatata ggtgaagaag ggaggggaga attatcaggc tagatgctta tgaaagagag
     6001 ctagtggctt attctaagga aattattgcc tacctagtga gatcaggtgt tgctaaggag
     6061 ctagcgcgtg atattagtca agacgttttg ttaaaaatgc ttgagagtga ccttgctctg
     6121 cctcctgaaa aaatacgtgc ctggatgtat cgggttgctg ttagaaaata cattgaccga
     6181 tataggcggg ataaggctta cttggatatt ctccaaaggg atttttttca tcaagaaagg
     6241 gttgttgaat ttgaccaccc caattatgag ccgctttata cagcagtcaa tgaattgcca
     6301 gaaaaatacc gctgggtctt gtcgttttat tactttcagg acctatcagt caaggaaatg
     6361 gcgtctctgc tccattggtc agttagcagc gtcaaggtca acttgatgcg gggaagacga
     6421 tgccttaaag aaaaactaaa gaaagcaggt tatacctatg acgatttcaa ctgattttga
     6481 agccattgct aagcgccata aaaggaggct gacccttaaa tatgtagtgc tgagtgctgg
     6541 cttagcctta gtagctcttg tactgggcta tatgggatta aatcgattga caagcatgaa
     6601 cggtcagtat ttaatggctt attacaacaa tcgtatacaa attgcttatc ccaatattga
     6661 tgttaatagc ttcttttaca atgccaattc gcagtttact ggtgagcttc attctgagcg
     6721 gaccaaggat attgctggga tttcggtacc gtttgagccc tatagagctc cttattcctt
     6781 gcctttaccc agagagagat ggactatacc aatgaatacc ttgtttcagg tgatgatgga
     6841 cggtcaacct acacaagagg tacacattat aaaatgcctc gcttcttcaa cactaaggcc
     6901 aagatcacag aaagcaacta tgacaagcca acgcaggacc tagactttat tgctgacatg
     6961 tcaggacagg cgattgaggt agccattacc tttgataagc cttatttatt atcggacata
     7021 gtcaagctgg ttccagacca gctaaagctg aattggatct ggattggcac agaaagcagc
     7081 tatgacacct cagggctttt ccctgctaat ttatatggct ttaagccaaa ctggaaggct
     7141 aatatgacgt acaaggagca aaagcagtta gataaaaaaa taaacgatat cctaaaaaag
     7201 gacagcgagg ctgatttgtc taagcttaat gctgcttacg ataagccagt cagtccaacg
     7261 gtggctctgc aaaattccta tgataccttc aggcactatc tacaagaggc agctgacaat
     7321 cattggatta atagtaccta tggcggcgct aatggatctc atttaagtga gcaggaggat
     7381 gtggccttat ttctaaaaaa caatcgcaat gtcaaaacag ctaagtttgc tggcattatt
     7441 ttaaccggca aggctgagca gtttgcctcc ttaaaaacag ctgattggat ttatgcctca
     7501 aatattggtc agtctgttgc cattcagccc tatcatcagc taaccaagta aataaaaagc
     7561 ttgtgctgct aatcaagcgc atcaggcaaa ggataaaaag cctaaaagag attagattaa
     7621 gtaaatcgat gcttaaaaaa gctccagctt aggtcaaaag acgtcaaaag gctcttggag
     7681 gtcagtgttt gatcactgct tctggggctt tttgctttgc tgcaatcaaa aaagcttgaa
     7741 gcagctctct caattgagca tgtccttcaa gctgagactc ttatatttta tagtatttgt
     7801 aagtatagtt ttagctagcc ttcttttaag cccaagggct tagcttactg tttagtatct
     7861 ttttctaaat tattgataat aactggataa tccttcaatg cagacttcat gtcatttaga
     7921 gtgctttgat atgctgtttg gtctgaggct accaatgcta gcttgtcatt ccatgcttta
     7981 tagtttaatg gctctgcctt tagagcagca tctaaatgat taagcttagt ctccttgtca
     8041 gtagctgctt cagccttata tcgttcatat tctgaggcat tataagcgtc tatattaaga
     8101 gagtagacgt tatgaatttg gacataagga agtgttgtgt tgtagttacc acagcctgtc
     8161 cagcctgaga catcatagcc gagctgatag gtatggtcag catttaagta gatataagca
     8221 cagtgacctg gttgtccaat aggaaaggct ggtacaccat aagcctgtgc tagcacacta
     8281 cttaatttag acatagcacc gcagacacca ccatatttga tgacttcctt gatggttgga
     8341 tttggtccgt aaaagccaga gctttggacg ctcacacctg tttctgggtt ggtcatgaca
     8401 tagctgatca gtgaatagcc cttagtaata tcattacggt taatcatagc aggcttattg
     8461 gtttcaacgt attgtcttaa ccatttcatg tcctcatcag taattttagc attgacgaca
     8521 tttcggattt gctcaacagt taagctgtaa aaatcttcaa ataggatatt gccctgctca
     8581 gcctctgcaa aggttgcaaa tctttcaagt ggatcaatct tgcggctttc attgtaccaa
     8641 gcacctacag gcttgttaaa ttccaaggca accgcaatgg ccattttgag ctgaatacct
     8701 tgatgtgagg tttcgtattt atcccaaatc ttaaaccaca attccaatgc ttctagctca
     8761 ttggtgaggt tataggtgtt tttgaattgg tatgatgaca tgccaccctg tgctgcagaa
     8821 tgggcatagc ctgcaccaag atataattgc attgcttcat tatctttgag caaccaatca
     8881 ataaaggctt tatgcttgtc gtcttgcttc ttgaagtcct cgattttttc cttggttagt
     8941 cttttttcaa cggcttgtac gagtgtatta gtagctttag cctctagtgc aaatacagaa
     9001 gccaaaccac ccttggtgat tcgaatctct gccttatttt tagggaggct aagagaaaca
     9061 gccttgtttt cttcatcata ggctttgact ctagtatggt gctcactacc agttaggcgg
     9121 atcttgtagc ccaccttgaa gggaatagtc tctgttttgg ctgttagagc ttggtttcca
     9181 ataaagtctt gtgtgtagac aaccttgtct tttaggtcta agacctcaag cttttcgtaa
     9241 gtcccactga agtaaacatg tggcttagcc tttttggttt tgagagttaa ggtagaggca
     9301 ttgtagtcaa cctttaaggt tgcgtattct gcattgccta agccaaggaa gcgcagcgtt
     9361 ctattactat catcaatacg ctcaagctgc ccgtttctca ccacataagt gtaagggttg
     9421 gtattgtttt gctttagagc gtcattgtgg ttagtgtaga agcggttagg ctcctgctta
     9481 gtgatgacta ggtaatagcc ttccttgaga gtaaggcttt ctgttttagc tgtttgggaa
     9541 acattaccca cgtattcctt agcataaacg gtttcttttt tctcattgag aatggttagg
     9601 gtagcgtaat tgttagcgat gtaagagtga ggctgtcctt ttttagtgac taagcttgca
     9661 gtgtaactgc cgtcagcata gaagtagagc tgagcaaata taccatttcc tagcccttgt
     9721 agagtaaatt gctgtagcag gctagctgcc ttatcaagta aacttaggat ttgctctttt
     9781 tcaggctctg ttgagtcagt cgcctttttc ctaagagcat ctattttttc ttgtgtgaca
     9841 ccacttgcta gcttacttgt agactcatct gtaaatagag tcagtacctc agactcaagc
     9901 tctgagcctg ttttagacct cattagctct agtgagtggt caagaagctt taaggttgct
     9961 tgatttttag agagtgttaa tggcgcttct accgcataat catcgtagaa tttcactctg
    10021 gtatggtgct cactacctgt caagcggatc ttgtagccta ctttaaaagg aatagtctct
    10081 gttttagctt cgaggacttg agttccaata aagtcctttg tgtagattac ttgattttct
    10141 gtatccagca cctcaagctt ttcataagat ccactgaagt aaacatgtgg cttggtctgc
    10201 ttggttttga gggttagggt agaggcattg taatcaaccc ttaaggttgc atactctgca
    10261 ttgcctaagc caaggaagcg cagcgttcta ttactatcat caatacgctc aagctgccca
    10321 tctctcacca cataagtata agggttggta ttgttttgct ttagagcgtc attatggtta
    10381 gtgtagaagc ggttaggctc ctgtttattg atgatgaggt aatagccttc ttttagctca
    10441 agctcttctg tttgtgctac ctgagaaaca ttgccggcgt attcttttga atagacggtt
    10501 tccttcttgt tattaagaat ggttatcgta gcgtaattag tagagaaata agagtgaggc
    10561 tggccccttt tagtgaccaa acttgcagtg tagctgccat cagcatagaa gtaaagttga
    10621 gcaaagacac cattgcctaa cccttgtagg gtaaactgct gtaataggct agctgcctta
    10681 tctagtagac ctaggatttg ctctttttca ggctctgttg agtcagtcgc cttttgcttt
    10741 aaggtatcta ttttttcttg tgtgacacca cttgccagct tactgcagga gttatctgta
    10801 aataaggctt gggtatcagt catcagttgt gatagcttag cctcggcaga aggagcagct
    10861 gtatcacctg cattaactgt agcggctatt ccatcagaag tatcagtagt tgcataaaca
    10921 attgctggag agagctgatg taatgttaat attccaacac atgctagtgc tattattttc
    10981 tttagtttca tcgttataaa gtccttttac aataaaataa agtgattcaa aactctggga
    11041 aaagaatagc tagccttaaa actatactcg caaatactat aaaatagaaa gactatttac
    11101 cctccttagc tcttgatgct gtggtgatga tattgttacg gtgctaaaaa tcctatccct
    11161 cctttttgac tattttgtct ctcttattcc ataatattaa aaaatcagaa tatgtcaata
    11221 tatattttct ttaatcctag aaatgataaa taggtttgga aaattcttaa tcattgatag
    11281 ccttaaaa
//
LOCUS       DARYMD010000060        11131 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYMD010000060 DARYMD010000000
VERSION     DARYMD010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11131
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            219..434
                     /locus_tag="TU818_001667"
     CDS             219..434
                     /locus_tag="TU818_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL0924461.1"
                     /translation="MDFFVQAVNVLKILVMAIGAGLGAWGVINLLEGYGSDNPGAKSQ
                     GIKQLMSGGGIVLIGLKLIPLLANVLR"
     gene            434..1297
                     /locus_tag="TU818_001668"
     CDS             434..1297
                     /locus_tag="TU818_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924462.1"
                     /translation="MFDLFGKIEEFFKDIMIDIIKDNLSAMLVDINDKVGTVAGEVGK
                     TPSSWNSEVFTFIKSINTNVVLPIAAIILTAILCIELIQVVMRKNSMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFDFSMAVFDVAQSMIGKAAGVVGTSANITPGNFDAMVEALKTKE
                     LGTLIGIALETGLVKFSLTILSILITVILYGRMIEIYIYCSVAAIPFSTMGNKEWSNI
                     GTNYIKSLFALGLQGLFILIFFGIYAVLVKTVNFTDIHTSILQVLAYGLILGVMMMKS
                     GSIAKAILNSH"
     gene            1370..1864
                     /locus_tag="TU818_001669"
     CDS             1370..1864
                     /locus_tag="TU818_001669"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0924463.1"
                     /translation="MNKINKKTRILIGAGSALSIGTIITVLLKKKTKKLSDLEEDDFD
                     FDFDEIEEDSCVNDKFATENDKDDTVKGEIDFLVDESKTENEKQEEFRDLSVKVMDLL
                     LKEVISMSETLNLVKRDIDRIGEVKALVEELENCKEEIISLWEHMEKLSDLREEITGK
                     KNRG"
     gene            1868..2278
                     /locus_tag="TU818_001670"
     CDS             1868..2278
                     /locus_tag="TU818_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL0924464.1"
                     /translation="MAYVKIPKDLTKVKTKVALNMTKRQLIGFSIAGLIGFPVYMLCK
                     NFLSTDISMIIMSIVVLPVLFVTLYEKDNLPFEKHLAYILRFHKSKKIRLYKARSIYH
                     TERAKKQDIGNKNKASGRRKKVEQRQKKKTGTTN"
     gene            2238..4715
                     /locus_tag="TU818_001671"
     CDS             2238..4715
                     /locus_tag="TU818_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEL0924465.1"
                     /translation="MNKDKRKKQEQRIKKDELELRKNRKELSELKKTGKKKTKSKTKG
                     KSSKKNGWFPFFMKEEKKETVQDTIPYKRMLKDGICQIEKNKFNKTIRFLDINYRLME
                     EIDQEGIFSEFSSFLNFFDSSVEVEFSYINSIGENEEINKLIDIKENIDDFNEIRNEY
                     RQMLLNQSSKGNNGLSKSMYITFTIEAEDLKQAKSRLERMEMDVLNNFKQMGVKAYVL
                     DGEERLKTIHDILNPNDKLVFSFEDLKYSGLTTKEYIVPPSFNFSKPTYFKTGEVFAE
                     VNFLQLLASDIKDEMLSEFLALEENMIVTFHIRAIDQMEAIKHVKRKITDLDKMKLEE
                     NKKAIRAGYDMDILPSDLVTYGAEAKNLLSELQNHDEKMFLITILFMNTSKSKGKLDN
                     TVFTLKSIANRHNCSLKNLNYRQEQGLVASLPLGINEVEIERGLTTSAAAIFIPFTTE
                     ELFIKGESLYYGLNALSRNIIMADRKKLKNPNGLILGTPGSGKSFAAKREITNAFLIT
                     DDDIIIADPEAEYSPLVEALKGQVIRISPISKDYVNPLDINIDYADEDNPLSLKSDFI
                     LSLFELVVGEKKLSAEEISVIDRCLPILYKTYFENPVPENMPILEDLYNLLQKQEEIV
                     GKKLAVEMEIYVKGSLNVFNHRTNVDTNNRVVCYDIKELGKQLKKIGMLVVQDQVWNR
                     VTINRASKKATRYYVDEFHLLLKEPQTANYSIEIWKRFRKWGGMPTGLTQNIKDLLAS
                     PEIENIFDNTDFILMLNQAGTDRDILAKKLNISKHQLSYVTNSGEGEGLIFYGNTIVP
                     FIDQFPKNTKLYSLITTKPEEVKKAGE"
     gene            4717..5742
                     /locus_tag="TU818_001672"
     CDS             4717..5742
                     /locus_tag="TU818_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL0924466.1"
                     /translation="MSVSRSKEEFIKENTNKIICSDALETLRKIPDESISCCITSPPY
                     YRLRNYHKEGQIGRESTVEEYLDRLLQVFREVRRALKKEGTCFIVIGDSYADSGGGKG
                     QYIDPKYPKARNGSNALATENISGYKSKDLMGIPWRLALLLREDGWYLRSDIIWHKEN
                     AMPEACRDRPTRSYEHIFLLTKSPKYYYDYDAMVEPMKEVSKKRYVRGRKSDNKYLKE
                     NSGAKLQKINEARKYGEYKGDNVPQFRNKRDIWTINTTSFRGNHYATFPPKLVEICMI
                     AGCPKNEIVLDPFIGSGTVGFVALRHNRKYIGIELNEEYVNLAKNRISEEVKKFNEEQ
                     KQEVQKE"
     gene            5708..7996
                     /locus_tag="TU818_001673"
     CDS             5708..7996
                     /locus_tag="TU818_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0924467.1"
                     /translation="MKNKNKRYKKNREKLLNQEIQSLQSQTQDNYETGSSKNQNETLL
                     KDETYDKKQFLSEKKLSNHLDNRHINNYSDRTISSYCLSDTGNINQNRSSFQAEKHKK
                     KMQKQINKFQKGEKEVYDPLSKDMDNDGVIDRYDVDFRDSKVSYRTLTDDEKYDNNQN
                     DKGKNYNDYVKNPKSKNKRYKNYVKDTFSKERMKSENQKKYVRSNFDDEEFTRNKDTK
                     NNLFQDVNNKRKTTDKNSSRKRKGKFENKEKKISKLQQKKQRQEQKLKNKGIDGKSQS
                     AKSAVIATGMAKRYLESGKEDNAGVGTAYKVTDQVENISRKIYYHGKKKNLKRQKKIT
                     KLGKSIDKQEKKLFFQKNMEEMKKSVDYQNTSRLRQFFKRRQYKNQIQKKYKDSVKNR
                     IKKSFIEGSKRFGEFVKGRGKKIIFLSLLAVGIFFMLFQAGSMMMNMGTGMVSNTVST
                     TYLSSEDTLKEINQRFSSLEQALQEEMDSVEENHPGYDEYIIKGKEKIGHNVHELLSY
                     ITARYGIVKNISEVESELKHLFQKMYTLTYKEEIEIRYRTVTSSYTDADGNEHTESHE
                     EPYEYRKLIVTLEKREMDGIIREAFKRYPNNLAHYETLFLTQGNMGEVFGNIDLINSN
                     GGIGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGFIGGNACDMY
                     RNYTFTSDRSKLKVGMLVAVESSSSGSSLGVTYGHVGIYIGDGKVMDNIGHIRVTTLD
                     DWIATFCKHHPVGFGFPPSVQK"
     gene            8009..8296
                     /locus_tag="TU818_001674"
     CDS             8009..8296
                     /locus_tag="TU818_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0924468.1"
                     /translation="MNKKYRKNIEKQKDIQKKIEELQLKQEMLKEEQEEMENIEVLKE
                     YRSIDISIDDFLEMMRRYKKEEKQEKMKLQEMRNTENHNNMEENHENQMEE"
     gene            8301..9737
                     /locus_tag="TU818_001675"
     CDS             8301..9737
                     /locus_tag="TU818_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL0924469.1"
                     /translation="MAITLSGVIFLILALLGTMLFNHQIVFAQGSLIPTLISPTEVLA
                     QTKVEVKIKYIFKDESVYKEEIIEVETGQVLDSGDLPMLEDNMKFIDEFLFYKVKGDG
                     TDEIIRKVEKITVKDKEIQTEEEKPKQDESTETEDKKTEDKGTQTELSKDDISKMEKE
                     AKELQDKLDKLNGEIRDKDKLSDKQKEKIKDLEAEIESLKEKMKKDKGNKDLSEDMKK
                     EIDKLTEKVKELEKKPTETNKAPVTSQSVTPISPISGIKTSSGISSQTPQSSGKGSSD
                     AVSSGNTTKDTGKTESKEKEKEVRYPNKLTPKAPANNSSQDSSMDGASSNVNTNKGVA
                     SAPSKARGTVTENKDNANNDYPIHHGDSSDNKEADKYSADARQFITFQTKSGKTFHLI
                     INHDEQSENVMLLTEVSEDDLLNMVEKKENPQEEIKKMEETVPESEVKKEEPKKEEGK
                     GSGSYIFLGIIVLAVVGAGYYFKIYKKK"
     gene            9990..10583
                     /locus_tag="TU818_001676"
     CDS             9990..10583
                     /locus_tag="TU818_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEL0924470.1"
                     /translation="MNYENKIEKYLKQSGGIITTAYCKENNIPTIYLSRLLKDGRLSK
                     VRKGIYITKDGDYDEYYFFQHQYKKAIFSYETALYLLGQTDKIPWSIDVTVYNGYKFN
                     EKPNGFNVHYVKKSIYDLGVTQKPTMFGNKVKVYSYERTLCDFIAHKEEMDIEVYVKL
                     IQSYSSYKERDIHSLYDIAMKMGIENKVREVMEVAYE"
     gene            10576..>11131
                     /locus_tag="TU818_001677"
     CDS             10576..>11131
                     /locus_tag="TU818_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL0924471.1"
                     /translation="MNKAKLTALCHKVSKEVGLSFNAVMLYYFLESILKKLAGSKYSE
                     RFIFKGGFLLSSVVGIDSRSTVDIDFLLRNMQLSEENIVQMLNETLKPEEFDDIFYEL
                     QNIVPIKEEDQYGGFRANILCKMENIRQIVPLDIATGDVITPHPIDYKYVSSFGEEEI
                     IIKAYPIETMLAEKIQTIYARGFLN"
BASE COUNT         4443 a         1409 c         2297 g         2982 t
ORIGIN      
        1 gatacttgga agtgtaaatg taagatgtat atttctaaaa ataatagaca ttaatttaaa
       61 agagagatgg gataaataaa atgaaaaata taataaaatc aataaggata agaagtccaa
      121 ctttaagaaa attgaatagc aaaagtttaa cgattggaag agaagatttc cagtcgtttt
      181 tttatgaaaa taagtaaaat aatgaggagg aataaattat ggattttttt gtacaggcag
      241 taaatgtgct taaaattttg gttatggcaa tcggtgcagg acttggtgca tggggagtta
      301 tcaacttact tgaaggatac ggatcagata atcccggtgc caagtcgcaa ggaatcaagc
      361 aattgatgag cggtggagga attgttttaa tagggctgaa actaattccg ctacttgcta
      421 atgtcttgag ataatgtttg atttatttgg aaagatagaa gagtttttca aggatattat
      481 gattgatatt attaaagata atctttctgc aatgcttgtg gatattaatg ataaagtagg
      541 aaccgttgca ggagaagtgg gaaagactcc gagttcttgg aactcggagg tcttcacctt
      601 cattaaatca atcaatacca atgttgtttt acccatagca gcgataattc taaccgcaat
      661 actttgcata gaactgattc aggtggtaat gagaaaaaat tctatgcacg atacggatac
      721 ctttgaattt tttaagtaca ttattaaaat gtggatagct gtatggcttg tgtctcatgc
      781 gtttgatttt tcaatggcag tctttgatgt ggcacagtcc atgataggaa aggcagcagg
      841 tgttgtgggg acaagtgcga atatcacacc gggaaatttt gatgctatgg tagaagccct
      901 taaaacaaag gaacttggaa cactcattgg gattgcactg gagacgggat tagttaaatt
      961 ttctttaacg attctatcaa tcttaatcac tgtaatccta tatggaagaa tgattgagat
     1021 atatatctat tgctctgttg cggcaattcc attttctacg atgggaaata aagaatggtc
     1081 aaatatcgga acaaactata taaaaagtct atttgccctt ggacttcagg gacttttcat
     1141 cctaatattt tttggaattt acgcagtctt agtcaaaacc gtaaacttta cggatatcca
     1201 cacaagtatt ttacaggtat tggcatatgg attgattctt ggagtaatga tgatgaaatc
     1261 cggaagtata gcaaaggcga ttttaaacag tcactaaagg actttagttc aaaatgagca
     1321 aaagttgatg aaataatcag aacaaaaaat ataattattg gaggtaagaa tgaataaaat
     1381 aaataaaaaa acaaggattt tgataggagc aggctcagcc ctttctatcg ggacaattat
     1441 tacagtgcta ttaaaaaaga aaacgaaaaa attatccgat cttgaagaag atgattttga
     1501 ctttgatttt gatgaaatag aagaagattc ttgtgtcaac gataaatttg ctacagaaaa
     1561 tgataaagat gatacagtaa aaggagaaat agatttttta gtagatgaat caaagacgga
     1621 gaacgaaaag caagaagagt ttagagattt atcggtaaag gtaatggatc ttcttctaaa
     1681 agaagtaatt tcaatgagtg aaaccttaaa tttggtaaaa agagatattg atagaatagg
     1741 tgaagtaaaa gcattggttg aagaactgga aaactgtaaa gaagaaatta tctcactttg
     1801 ggagcacatg gaaaagttat ccgatttaag agaagaaatt accggcaaaa agaatagagg
     1861 ttaggctatg gcttatgtaa agataccaaa agaccttaca aaagtaaaaa ccaaggtagc
     1921 cctgaatatg acaaaaaggc agcttatagg ttttagcata gcagggctta tcggttttcc
     1981 tgtatatatg ctgtgtaaaa attttcttag tacagatatt tccatgatta taatgagtat
     2041 agtagttcta cctgttcttt ttgtaacgct ttatgaaaag gacaatttac cttttgaaaa
     2101 acatttagca tatatcctca ggtttcataa aagtaaaaag atcaggctat ataaagcgag
     2161 gagcatttat catacagaga gagcaaaaaa gcaagatata ggaaataaaa ataaggcaag
     2221 cggaaggagg aaaaaagttg aacaaagaca aaagaaaaaa acaggaacaa cgaattaaaa
     2281 aggatgagtt ggagcttagg aaaaatagaa aggagctatc cgaacttaaa aaaacaggaa
     2341 agaaaaaaac aaagtctaaa acaaaaggga aatcatcgaa gaagaatggg tggtttcctt
     2401 tttttatgaa agaggagaaa aaagaaaccg tacaggatac cattccatat aagcgaatgt
     2461 taaaagacgg gatttgtcaa attgaaaaga ataagtttaa taaaaccatt cgatttttgg
     2521 acattaacta tcgcttaatg gaagaaatag accaagaggg aatattttcg gaattttctt
     2581 cttttctaaa tttctttgac tcatctgtgg aagtggagtt cagctatatc aacagtatcg
     2641 gagaaaatga agaaatcaat aaactgattg atattaagga aaatatagat gattttaatg
     2701 aaattagaaa cgaatataga caaatgctct taaatcaaag cagcaaaggg aataatggat
     2761 tatcaaagag tatgtacatt acctttacca tagaggcgga ggacttaaag caggcaaaaa
     2821 gtagattaga gcgaatggaa atggatgtat taaacaactt taagcagatg ggagtgaaag
     2881 cctatgtgtt agatggagag gaaagactta aaacaattca tgacatttta aatccaaatg
     2941 ataaacttgt tttttccttt gaggatttga aatacagcgg actgacgact aaggaataca
     3001 ttgtacctcc gtcttttaac ttttccaagc cgacgtattt taagacagga gaagtctttg
     3061 cggaagtaaa ttttttacag cttttagcat cagatattaa agatgagatg ttatcagagt
     3121 ttttggcatt ggaagaaaat atgattgtta cttttcatat cagagcaatc gaccagatgg
     3181 aagctattaa acatgtaaaa agaaaaataa cggatttgga taagatgaag cttgaggaaa
     3241 acaaaaaagc tattcgtgcg ggatatgata tggatatctt gccaagcgac cttgtaactt
     3301 atggtgcaga ggcaaagaac ttgctatcag aactacaaaa ccatgatgaa aagatgtttc
     3361 tcataacaat tttatttatg aacacgagta aaagtaaggg gaaactcgat aatacggtat
     3421 ttaccttaaa gtccattgca aatagacata attgtagttt gaaaaaccta aattatagac
     3481 aagaacaagg gcttgttgca agccttccac ttgggataaa tgaagtggag atagaacgag
     3541 gacttaccac aagtgcagca gctattttta taccatttac aacagaagaa ctctttatca
     3601 agggagaaag cctatattac ggactaaatg cactaagcag aaatattatt atggcggaca
     3661 ggaagaaatt aaagaaccca aatggtctaa tcttagggac accgggttct ggaaagtcct
     3721 ttgcagccaa aagagagatt actaatgcgt ttttgattac agatgatgat attatcattg
     3781 cagatccgga agcggaatat tctccgcttg tagaggcact aaaaggacaa gttatcagaa
     3841 tttctccgat ttcaaaagac tatgtcaatc cactggacat caatattgac tatgcggatg
     3901 aagataatcc tttgtcttta aaatccgact ttattttgtc cctatttgaa ttggtggttg
     3961 gagaaaagaa attaagtgca gaagaaattt ctgttataga ccgttgttta ccaattttat
     4021 ataaaaccta ctttgaaaat cctgtgccgg aaaatatgcc aattttagag gatttatata
     4081 atcttcttca aaaacaggaa gaaatagtag gaaaaaagct tgcagtagaa atggagatct
     4141 atgtaaaagg aagtcttaat gtatttaatc atagaacgaa tgtagataca aataacagag
     4201 tggtttgcta tgacatcaaa gaactgggaa aacagcttaa aaagatagga atgttagttg
     4261 tgcaggatca agtttggaat agagttacaa ttaacagagc aagtaaaaaa gcaaccagat
     4321 attatgttga tgaatttcat cttttgttga aagaaccgca aacagccaat tattcgattg
     4381 aaatctggaa gcgtttcaga aaatggggtg gtatgccaac aggacttact caaaatatca
     4441 aagaccttct tgcaagcccg gagattgaaa atatttttga taatacggat tttattttaa
     4501 tgcttaatca agcaggaaca gatagggata ttttagccaa gaagctcaat atctccaagc
     4561 atcagctttc ttatgtaaca aattcggggg aaggagaagg acttatcttt tatggaaata
     4621 cgattgttcc ttttatcgat cagtttccaa aaaatacaaa actatattca ctaatcacaa
     4681 ccaaacctga agaagtaaaa aaggcaggtg aataggatga gtgtgagcag aagtaaagag
     4741 gaattcatca aagaaaatac aaataaaatt atttgttcgg atgcacttga aactttaaga
     4801 aaaattccag acgaaagtat aagctgctgc attacatctc ccccatacta caggctcaga
     4861 aactatcata aagaaggtca gataggaaga gaatctacag tagaagaata cttggataga
     4921 ttgttacagg tatttcgtga agtaagaaga gctttaaaaa aagaaggtac ttgctttatc
     4981 gtaattggag attcttatgc tgattcagga ggtggaaagg ggcaatacat tgatcctaaa
     5041 tatccaaagg caagaaatgg aagtaacgct ttagctacag aaaatatctc agggtacaag
     5101 tcaaaagatt taatgggaat accttggaga ttagcgttac ttctaagaga ggatggttgg
     5161 tatctgcgtt ctgatattat ctggcataag gaaaatgcta tgccggaggc gtgtagagat
     5221 agacctactc gttcctatga acatattttt ttacttacga aatcaccaaa atactattat
     5281 gactatgatg ctatggtaga gccgatgaaa gaagtcagta aaaaaagata tgtaagagga
     5341 agaaaatcgg ataataaata tctgaaagaa aattccggag caaagttgca aaaaatcaat
     5401 gaagcaagaa aatatggaga atataagggc gataatgtcc cgcagtttcg taataaaaga
     5461 gatatttgga ctatcaatac cacatctttt agaggcaatc attatgcaac atttccaccg
     5521 aaacttgttg agatttgtat gattgcaggt tgtcctaaaa atgaaattgt acttgatcct
     5581 ttcattggaa gtggaacggt cggatttgtg gcacttcgtc ataacagaaa gtacattgga
     5641 attgaattaa atgaggagta tgtaaatctt gcaaagaata gaatcagtga ggaggtgaaa
     5701 aaatttaatg aagaacaaaa acaagaggta caaaaagaat agagaaaaac tcttaaatca
     5761 agaaatacag tctttacaat ctcaaactca agataattat gaaacaggat cctcaaaaaa
     5821 tcagaatgaa accttgctga aagacgaaac ttacgataag aaacaatttt tatctgaaaa
     5881 gaagttatcc aatcatttgg ataatagaca tataaataat tattcggata gaactatatc
     5941 ttcttattgc ttgtcggata cgggaaatat aaatcaaaat aggtcttcct ttcaagctga
     6001 aaaacataaa aaaaagatgc aaaagcagat aaataaattt caaaagggag aaaaggaagt
     6061 ctacgatcct ttatcaaaag atatggataa tgatggtgta atagacaggt atgatgtgga
     6121 ttttagggat agcaaagtat catatcgaac tcttacagat gatgaaaagt atgataataa
     6181 ccaaaatgat aaaggaaaaa attataatga ctatgtaaaa aatccaaaat ctaagaataa
     6241 gaggtataaa aattatgtaa aagacacatt ttctaaggaa agaatgaaat cagaaaacca
     6301 gaagaaatat gtgaggagca actttgatga tgaagagttc acaagaaata aggatacgaa
     6361 aaataattta tttcaggacg taaataataa aagaaaaact accgataaaa attcatcacg
     6421 aaaaagaaaa ggaaaatttg aaaataagga aaagaaaata tccaagttac agcagaaaaa
     6481 gcaaagacaa gagcaaaaac tgaaaaataa gggaattgac gggaaaagtc aaagtgctaa
     6541 aagtgcagta atagcaacgg gtatggcaaa gaggtatttg gaaagtggaa aagaggacaa
     6601 tgccggagta ggtactgctt ataaggttac agatcaggtc gaaaatattt caaggaaaat
     6661 atattatcat ggaaaaaaga aaaatttaaa aaggcaaaaa aagataacaa aattaggtaa
     6721 aagcattgat aaacaggaga agaaactctt ttttcaaaag aatatggaag agatgaaaaa
     6781 aagcgtggat taccaaaata cctcaaggct cagacaattc tttaagagaa ggcaatataa
     6841 aaatcagatt caaaagaagt ataaagatag tgtgaaaaac agaataaaaa aatcctttat
     6901 agagggcagt aaaagatttg gcgaatttgt aaagggcaga gggaaaaaga taatatttct
     6961 atcactttta gcggtaggaa tattttttat gttatttcag gctgggagca tgatgatgaa
     7021 tatgggaacg ggaatggtaa gtaatactgt ttcaaccacc tacttatcat cagaagacac
     7081 cttaaaagaa atcaatcaga ggttttcatc tttggaacag gctttgcaag aagaaatgga
     7141 cagtgtggag gaaaatcatc cgggctatga tgaatatatt atcaaaggaa aagagaaaat
     7201 tggtcataat gttcatgaac tcttgtcata tatcacagcc cgttatggaa ttgtaaagaa
     7261 tatttctgaa gtagaaagtg aactaaaaca tctgtttcaa aaaatgtata cgctgactta
     7321 taaagaagag attgaaatca gatatagaac tgttacatcc agctatacgg atgctgatgg
     7381 caatgaacat actgaaagtc atgaagagcc gtatgagtat aggaaactca ttgtaacctt
     7441 agaaaaaaga gagatggacg gaattattag agaagcattt aagcgttatc ctaataattt
     7501 ggcacactat gaaactttat ttttgacaca aggaaatatg ggagaagtat ttggaaatat
     7561 tgaccttata aattcaaatg gtggaattgg tggtggtaaa gagtatgaag catcaagtga
     7621 agtgcaaaag aaaatagtga atgccgctta tattacacca tctccaggag caggttggtg
     7681 tgccatgtgg gtatcacagg tctatcaaaa tgcaggactt ggatttattg gaggaaatgc
     7741 ttgtgatatg tatcgaaatt atacttttac ttctgatagg tcaaagttaa aggttggaat
     7801 gcttgttgca gttgaaagta gcagtagtgg tagcagttta ggtgttacct atggtcatgt
     7861 aggtatttat atcggagatg gaaaagtaat ggataatatc ggacacataa gagtaactac
     7921 cctagatgat tggattgcaa cattttgcaa acatcaccct gtaggttttg gatttccacc
     7981 atcagtacaa aaataaggag ggaatatttt gaataaaaaa tatagaaaaa atatagaaaa
     8041 gcaaaaagat attcagaaaa aaatagaaga actccagtta aaacaggaga tgttaaaaga
     8101 agaacaggaa gagatggaaa atattgaggt tttaaaggaa taccgaagta ttgacatttc
     8161 tattgacgat tttttagaaa tgatgagacg ttataaaaaa gaggaaaaac aagaaaaaat
     8221 gaagttacag gaaatgagaa atacagaaaa tcataataat atggaggaaa atcatgaaaa
     8281 tcaaatggaa gaataaaaaa atggcgataa cattgtccgg agtaatcttt ttgatacttg
     8341 ctttacttgg aacaatgctt ttcaatcacc agattgtttt tgcacaaggt agtttaatcc
     8401 cgacactgat tagtcccaca gaagttttag ctcaaactaa agtggaggtt aagataaaat
     8461 atatatttaa ggatgagagt gtatataagg aagaaataat tgaagtagaa accgggcaag
     8521 ttcttgacag tggggaccta ccaatgttag aggataatat gaaatttatt gacgaatttt
     8581 tgttctataa agtaaaggga gacggtacag atgagattat ccgtaaagta gaaaaaatta
     8641 cagttaagga taaagaaatt cagacagaag aggaaaagcc aaaacaggac gaaagcactg
     8701 agacggaaga taaaaaaaca gaagataagg gaacacagac agagctttct aaagatgata
     8761 tttccaaaat ggaaaaagag gcaaaagagc ttcaggataa acttgataaa ttaaatggtg
     8821 aaatcaggga taaagacaaa ctaagcgata aacagaaaga aaaaatcaaa gaccttgaag
     8881 ctgagattga aagtctgaaa gaaaaaatga agaaagataa gggaaataaa gacttatcag
     8941 aagatatgaa aaaggaaata gataagctga cggaaaaggt gaaagagctt gagaaaaagc
     9001 caactgaaac aaacaaagct cctgtaacat cacagtctgt tacaccgatt agtcctattt
     9061 cagggattaa gacaagctca ggtatttctt ctcaaacacc acagagttcc ggtaaaggtt
     9121 catctgatgc agtaagctcc ggcaatacta caaaagatac aggtaaaact gaatcaaagg
     9181 agaaagaaaa ggaagttcgc tatcccaata agctgacacc gaaagctcct gctaataaca
     9241 gtagtcagga ttcatcaatg gacggtgcaa gtagcaatgt aaataccaat aagggtgtgg
     9301 cttcagctcc gtcaaaggca agaggaactg ttacagaaaa taaagataat gcgaataatg
     9361 attatccaat tcatcatggg gatagcagcg ataacaaaga agcagataag tattcagcag
     9421 atgcaagaca atttattact ttccagacaa aatccggaaa gacatttcat ttaatcatca
     9481 atcacgatga gcaaagtgaa aatgtaatgc ttttgactga agtatctgaa gatgatcttc
     9541 tgaatatggt agagaagaag gaaaacccgc aagaagaaat caaaaaaatg gaagaaacgg
     9601 taccggaaag cgaagtaaaa aaagaagagc cgaaaaagga agaaggtaaa ggtagcggct
     9661 catatatttt tttaggaatc atcgttcttg cagtagttgg agcaggatat tactttaaaa
     9721 tctacaagaa aaagtaggaa gatgatgatt atgatgaaga tgaggaagaa tatgatgaat
     9781 ttgaagatga gtatgaaaaa gaggacgata cagaagattt ggaagaaaca gtagaagaac
     9841 agcataacat agatgatatg gcaatcgact cttatgatga agaagatgag gaataaagtt
     9901 ataaaaagag aaatgtaaac cctgatgttg cgtttacact taaaaaatgg tataatgcaa
     9961 gtgtaaacgc aacaaagggg gtggatggga tgaattatga aaataaaatt gaaaaatatt
    10021 tgaagcaatc aggtggaatt attacaacag catactgtaa ggaaaataat ataccgacga
    10081 tatatctcag tcgactattg aaagatggga gattgtcaaa agtaagaaaa ggaatttata
    10141 taacgaaaga tggggattac gatgagtatt atttctttca acatcagtat aaaaaggcga
    10201 tattttctta tgaaacagca ctttacctgc ttggacaaac agataaaatt ccttggagta
    10261 tcgatgtaac cgtttataac ggatataaat ttaatgaaaa accgaacggt ttcaatgttc
    10321 attatgtaaa aaaatcaatt tatgacttag gggtaaccca aaaacctaca atgtttggaa
    10381 ataaagttaa ggtatattca tatgagagga cactctgtga ttttattgct cataaagaag
    10441 aaatggatat agaggtttat gtaaaactta ttcaatcata ttcctcttat aaagaaagag
    10501 atatccattc cctctatgac attgcaatga aaatgggaat tgaaaataaa gtaagagagg
    10561 ttatggaggt ggcttatgaa taaagctaaa ttaacggctc tttgccataa agttagtaaa
    10621 gaagtcggtc tttcgtttaa tgctgttatg ttatattatt ttttagaaag tattttaaaa
    10681 aaattagcag gaagcaaata tagtgaacga tttattttta agggcggctt tttgttatca
    10741 agtgtagttg gaattgattc aagaagtact gtagatatag actttctttt gagaaatatg
    10801 caactatcag aagaaaatat tgttcaaatg ctgaacgaaa ctttaaaacc ggaagaattc
    10861 gacgatattt tttatgaatt gcaaaacatt gtgccaatca aagaagaaga tcaatatgga
    10921 ggatttcgtg caaatatctt atgtaaaatg gaaaatataa gacagattgt accacttgac
    10981 attgcaacag gagatgttat tacacctcat ccgatagatt ataagtatgt gagttctttt
    11041 ggagaagaag aaataataat caaggcttat ccgatagaaa ctatgcttgc agaaaaaata
    11101 caaactattt atgcaagagg atttttaaat a
//
LOCUS       DARYMD010000061        10986 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYMD010000061 DARYMD010000000
VERSION     DARYMD010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10986
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..793
                     /locus_tag="TU818_001678"
     CDS             <1..793
                     /locus_tag="TU818_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL0924472.1"
                     /translation="RLKECYPQLSFAEPMISSTMALESIKLSARVSLFKTIKNVSAIK
                     KSFYPCNMEELDQPTGYLLYRTHLARHSKEERLRVIDARDRIQLFLDEKHVKTQYQEE
                     IGQDILIHQEGETTQLDILVENMGRVSYGYKLTAPSQQKGLGRGLMADLHFVGDWEHF
                     PLDFQELDWIDFSAGWTDEVPGFYAYDFDCQQPADTYLDLSQFGKGIALVNGVNLGRF
                     WKVGPTLSLYIPKGLLKQGQNRLLIFETEGQFSESIRLTKEPIYK"
     gene            811..1296
                     /locus_tag="TU818_001679"
     CDS             811..1296
                     /locus_tag="TU818_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0924473.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLELIQKGVAISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            1342..2223
                     /locus_tag="TU818_001680"
     CDS             1342..2223
                     /locus_tag="TU818_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL0924474.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLSLATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            2210..3028
                     /locus_tag="TU818_001681"
     CDS             2210..3028
                     /locus_tag="TU818_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL0924475.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGGIFWLLGRKGMSPTKAIVVIILFALVMSYFNILGV"
     gene            3032..3436
                     /locus_tag="TU818_001682"
     CDS             3032..3436
                     /locus_tag="TU818_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL0924476.1"
                     /translation="MAQTLILISHGAFCRELKQSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEAFDFKAFACDNIHHVNTIISALADDDDD"
     gene            complement(3540..3800)
                     /locus_tag="TU818_001683"
     CDS             complement(3540..3800)
                     /locus_tag="TU818_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL0924477.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(3925..4857)
                     /locus_tag="TU818_001684"
     CDS             complement(3925..4857)
                     /locus_tag="TU818_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL0924478.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDVYGDLSYVDTKTSSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYAFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDDSGAARLL
                     LSQEVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(4867..5295)
                     /locus_tag="TU818_001685"
     CDS             complement(4867..5295)
                     /locus_tag="TU818_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0924479.1"
                     /translation="MWVVKAFDQLTKDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQNARRTGLGRDLVHQALAYCQQHFPK
                     LPVYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            5553..6578
                     /locus_tag="TU818_001686"
     CDS             5553..6578
                     /locus_tag="TU818_001686"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL0924480.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSDTNLTKEYELFVKHFETSVTDFLEHNRDAIKASFASPAEKEALLDRLEKA
                     YQSYIKK"
     gene            6639..7085
                     /locus_tag="TU818_001687"
     CDS             6639..7085
                     /locus_tag="TU818_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL0924481.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            7414..7707
                     /locus_tag="TU818_001688"
     CDS             7414..7707
                     /locus_tag="TU818_001688"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL0924482.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMVLADQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKTIMAVSRRYQAEQIAVGSNDDEAY"
     gene            7688..8920
                     /locus_tag="TU818_001689"
     CDS             7688..8920
                     /locus_tag="TU818_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL0924483.1"
                     /translation="MMMKPIKNNQDISIGDNVYLAFAALLVGVVVGVIDTVFGQGLLL
                     LSAVRDAHLIYLLPCLALAGLVIVFLYEQYGQIAKQGMGLVFDVGHGEKTRLPLVLIP
                     LIILSTWLTHLCGGSAGREGVAVQIGATVSHFFGRLRHLKDKSQLFLVMGMAAGFAGL
                     FQTPMTAVVFALEVLLLGNISYLALLPSLIAAFTASWTSHCLGLEKFSVPIAKALKIT
                     PITFGKLVLLGLIFGLAGNLFASLLARAKPYIAARLPNPYYRVLLVGGFLSLSLLLCH
                     YGRYSGLGTNLITAAFSHQPIANYDWLLKLLFTIITLSAGFQGGEVTPLFAIGAALGI
                     VLAPWLGLPAQLAAALGYAAVFGSATNTFLAPIFVGLEVFGATNATAYFIVIAFAYMV
                     SRRHSIYTKQRVTTSIAS"
     gene            9066..9413
                     /gene="rplS"
                     /locus_tag="TU818_001690"
     CDS             9066..9413
                     /gene="rplS"
                     /locus_tag="TU818_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL0924484.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            9928..9999
                     /locus_tag="TU818_001691"
     tRNA            9928..9999
                     /locus_tag="TU818_001691"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9961..9963,aa:Arg,seq:cct)
     gene            complement(10123..10926)
                     /locus_tag="TU818_001692"
     CDS             complement(10123..10926)
                     /locus_tag="TU818_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0924485.1"
                     /translation="MSKSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDENQHTEEGNNLATEELDEAA"
BASE COUNT         3027 a         2105 c         2515 g         3339 t
ORIGIN      
        1 acgtctcaag gagtgttacc ctcaattatc ctttgcagag ccaatgatca gttctacgat
       61 ggccttagag tctatcaagt tgtcggcaag ggttagtctt tttaagacaa tcaaaaatgt
      121 aagcgctatc aagaaaagtt tttatccttg taatatggag gagctagatc aaccaacggg
      181 ctacctactg tatagaacgc acctcgctag acatagcaag gaggagcggc tcagggtcat
      241 tgatgctaga gaccgcattc agctcttttt agatgaaaag cacgtgaaaa cccagtatca
      301 ggaggaaatc ggtcaggata tactgataca tcaagagggt gagaccacac agcttgatat
      361 tttagtcgaa aatatgggac gtgtcagcta tgggtacaag ctgacagcac caagccaaca
      421 aaaaggatta ggcagaggct taatggctga cttgcatttt gtaggtgatt gggagcattt
      481 tccactagat tttcaagagc tggattggat tgatttttct gcaggttgga ccgatgaggt
      541 gccaggattt tacgcctatg attttgattg tcagcagccg gcagatacct accttgattt
      601 gagtcaattc ggaaaaggaa ttgcccttgt aaatggtgtt aacctaggac gtttttggaa
      661 ggtcggtcca acattatcgc tttatattcc taagggacta ttaaaacaag gtcaaaatag
      721 actgctgata tttgaaacag aagggcagtt tagtgagtca attcgtttaa ctaaggaacc
      781 aatttataaa tagataaaag gagaaaactt atgacaattg ttgcagcacg tattgacggc
      841 cggttaattc atggtcaggt agctaatcta tggacgacaa agctaaacat tagccgtatc
      901 atggtggtcg ataatgaggt gattagcaat gaccttgaaa aaacagcact gaagctagcc
      961 acacctagcg gtgttaaatt atctatctta tctgttgaaa aagcagccaa caatattttg
     1021 gaagggcgct atgattctca acgcttgttg atagtagcca gaaagccgga tagctttttg
     1081 gagctgattc aaaaaggggt tgctatttca gagttaaatg tcggcaatat gtcacagaca
     1141 ccggagactc gtccagtaac gcgttctatt aacgttgtag acgaggatat agaggcattc
     1201 aaggctattt cagccaaagg gtgtcatctc attgcccaaa tggtgcctaa tgatgcccca
     1261 gcagacttta tgccgctgtt ggataaggtt gattaagatg tgtcaaatca aaaacgaatc
     1321 tgtttcagga ggtaaaagct tatgattcaa tggtggcaaa tcctattatt aacactctac
     1381 tcagcttatc aaatattaga tgagctaaca attgtctctt ctgcaggctc acctgtattt
     1441 gcaggattta tttcaggtat catcatggga gatgtgcaaa ccggtctttg gattggtggt
     1501 agccttcaat tgatggtgct tggtgttggg acctttggag gagcttcgcg tatcgatgca
     1561 acctctggtg cggttattgc gacagccttc tcggttgctc aaggcataga gccagaatta
     1621 gcgatttcaa ccattgcagt tccggtagcg gccttgctgg tttatactga tattctagga
     1681 cgcttttcaa cgaccttctt tgctcaccgt attgaccgcc atgttgaaaa ctttaactac
     1741 cgaggcatcg agcgtgatta ccttatggga gctgtacctt gggccctatc acgtgctctg
     1801 ccggtatttt tagcggtctc tttaggtggt ggtgcggttg atacagttgt taagttcatt
     1861 gaccattatg aatggctagc aaatggtcta actcttgcag gaaaaatgct tccaggcttg
     1921 ggctttgcga tcttgcttca ctacctacca gttaaacgta atctccatta tctggcttta
     1981 ggttttggct tgacagcaat gctaacaacc atttacacca accttcaggt agctggaggc
     2041 gcccttgcag gagtagccaa ggatttcaat gccgcaccat tcaaggggct gccaatgatt
     2101 ggtattgcta ttattgggct ttccttggca accctccatt ataaaaatgg tcaacaagca
     2161 cctgtagctg aacaaaaacc tggggtatca gaaagtgggg aaattgaaga tgacgaaatc
     2221 taattataaa ttaaccaaac aggattttaa tcaaatcaat aagcgcagcc tgttcacatt
     2281 ccaatggggc tggaactacg agcgtatgca gggctctagc tatctttaca tgattttacc
     2341 acagcttcgt aagatttatg gcgatggaac tccagagcta aaagaaatga tgaagacgca
     2401 cacgcagttt tttaacacat caaatttctt tcatacgatt atcacaggaa ttgacttggc
     2461 gttggaggaa aatgaaggac ttgcctcaaa agatgctgtt aatgggatta aaacaggctt
     2521 aatggggcca tttgctccaa ttggtgattc ggtctttggc tccttagtac cagctattat
     2581 gggctctata gccgcaggtc ttgctaaaga aggggtttgg tcagggatta ctggtgtatt
     2641 gatgtgggta tgtactcaga tgatcatcaa tgtgtttcgt tggaagcagc ttgaaattgc
     2701 ttataaagaa ggtacaaagc tcgtcaccac catgcgtgat aagctaactg ctgtagtaga
     2761 tgcagcctca gtcatgggag tattcatggt aggggcctta attgcaacaa tgattaattt
     2821 tcagtttacc gcagcaccca aaattggaga gaaagttatc aatattcaag atttaattga
     2881 taccattttt ccacgtctag ttccagcctt atttaccgga ggtatcttct ggctgctagg
     2941 gcgtaagggc atgtcaccaa ctaaggcaat tgttgtgatt attttatttg ccttagtgat
     3001 gtcttatttc aatattttag gagtatagct gatggcgcaa accttaattc tcattagtca
     3061 tggagctttt tgtcgagagc taaaacagag tacagaaatg attatggggc cacaggacaa
     3121 tattttaaca gcagagctgc aaccaaacga aggtgccgat gactttaaag aaaagctttt
     3181 aaggctaatt gcaggtttag atgacgtcct tgtgtttgca gatttgatgg gtggaacacc
     3241 ctgtaacgtt gccagtcgtt tgttaatgga aggacatcag tttgagctgt acgcaggcat
     3301 gaatatgcca atggtcattg gtttcattaa tgcctgtttg atcggtgaag cgtttgattt
     3361 caaagccttt gcctgtgaca atattcacca tgtcaatacc attatttcag ctctagcaga
     3421 tgatgatgac gactaaccaa gctcgcttat ttgtcacgca ccttacggag cgaaacggac
     3481 caagagccgc ataatcaaaa aagacactgc caaatcttgg cagtgtcttt gctgtaagct
     3541 tattttgctg cgtttgcgtc tttgagaccg tatttcttgt tgaaacgatc cacacgtcca
     3601 tcggcttgtg taaacttttg acgacctgtg tagaatgggt gtgagtctga tgaaatttct
     3661 acacgaacaa gagggtaagt ttccccttca aactcaatgg tttctttaga ggtcttagtt
     3721 gaaccgctaa ggaatttgta gcctgtagtt gtatcaagga aaacaactgg acgataatct
     3781 ggatgaatgt cttttctcat cttaaaaaag ttcctttctg ccatgatact gtccgtatca
     3841 tagttattaa ctactctagt ttaacaaaag ttagtaagct tgacaagctt tttctatcac
     3901 tattcatcaa taagatgata agtcttatgt taagagatca atcagctctt ggtagatttg
     3961 ctcattttcc tctaagcctg atgacgtggc accgctagca agagggtgcc cgcctccttg
     4021 atgacgctta gcaataccat tgatgacctt ttctttactg cgcatgcgta ctcggtactg
     4081 gccatctggc agctcaacaa agataaccca agcctgcacc acgtctattt ttccaggagc
     4141 agagacaatc gctgagcttt ctgccaagct aataccaaag gaatttagga cctcctggct
     4201 aagcagtagg cgggctgcac cactgtcatc tatatcaagc tgctcaaaaa catagccttg
     4261 tagcttggca attttaagtg gaaaggaatc catctgcctc gaaatagcag caaagtcaaa
     4321 ggcataattt cttaattggc ttgcaatggc cagtgtttta ctgcttgttg aggcatagag
     4381 aaagcgtcct gtatctccca caatgccagt atataatagt ctagctgcct catcagttaa
     4441 agccaagcct tggctaaagg caaattcagc aataatctca ctagcacttg aggtcttggt
     4501 gtcaacgtag gagagatcac catagacatc atcgttaggg tgatgatcaa ttttaatgag
     4561 gcaagcgccc attgtgtagc gctcatcatc aatgcggggg cgattggcag tgtctgtaac
     4621 aatcactaaa gcttccttat aatcatcgtc ggacacctga tccatgagac taatccaagc
     4681 cagactaggc tcatcaaagc ctgttatcag gacctttttg tcagggaaat tatgcctgat
     4741 aatctcttta agtcctgctt ggctccctag agcatctgga tcggggtttt ggtgccgatg
     4801 aatgatgatg gtttgatagt gcttaatgtg ttctaaaata gtttgaaacg ttgtcatagg
     4861 tatcctttag tttttgatca tatcaatgtg aggaatattg tcttccagat aaatctcaga
     4921 gactgcttta aacccaaatg agctgtaaaa aggctcaaga taagcctgcg cttgagcgta
     4981 gacgggaagc tttggaaagt gctgttgaca ataggctaag gcttgatgaa ctaagtcacg
     5041 tcctagtcct gttcgccttg cattttgtgc taccagtact cgtcccagct ttatgctatt
     5101 gtcagttggg attaagcgac agtaggccct aagctctgaa tcaacctgct tgaaaagatg
     5161 gatagctttt tgatccaaat cgtcaatatc aggataggga cattgctgct caaccacaaa
     5221 aacagccaca cgctctttat agatggcaaa caattcatct tttgttaact gatcaaatgc
     5281 tttaacaacc cacattagct agcctccaaa atcactggta caatttcctt tatgataaca
     5341 taatagcata tatcagccat aatggaacga aaaaaacctg actcttaatg gacgatgtcg
     5401 tgatgataat tacatcttgt ctcaaaagct ggtaatcatc acaggcacag aaaaatgtgc
     5461 cccttctgtt gctttttgag aaaaagttca cttgcttttt ggtagttttt tggtatcata
     5521 ctaaaaaata gacttaatta aggagataca gcttggaaac aaaagattta aagaagcttg
     5581 ctaaagctga gctgcactgc catttagacg gttctttgtc attagacact attcgtcagt
     5641 tggcggcttt ggcgcaggta gatgttcctc aagatgattc tgagttaaag cagctggtaa
     5701 ccgcaccgga aacctgtgaa tccttgatgg attatttaaa aacctttgat gttatcagac
     5761 cattattaca aacgcctcag gctttaacat tggctgctta tgatgttgtg aagcaggctg
     5821 cccttgaaaa tgtcatctac attgaaattc gatttgctcc tgagttgtca atggatcagg
     5881 gcttgaccgc cactcaggtg gtagaggcag ttttaaaagg actcgagcaa ggacaaaaag
     5941 agtttggcat tgtcgctaag gctattgtgt gtggcatgcg tcagtcctca ctagacatta
     6001 gcagagagat ttttgcaaat gtcttagagt gggccaataa aggcttggta ggctttgatt
     6061 ttgcaggcaa cgagctggac tttcctccag ctgtcttagc agatttgatc aaagagacgc
     6121 aggcctatgg gttaccattt acgcttcatg ctggtgagtg tggctgtcca aactatattg
     6181 ttgatgctat tgatttaggt atcaaacgct tagggcatgt gacggccatt cataaccaaa
     6241 aggatttatt ggccaagttt atcgccaatg atgtgacagc agagctgtgc ttcactagta
     6301 atctacaaac caaggctgct aggactgttg aggactttcc ttatatgcag ctaaggcagg
     6361 ctggcgctaa attatccatt aacacagaca atcgaacagt atccgatacc aatctgacaa
     6421 aggaatatga actgtttgtc aagcactttg agacaagcgt cacagacttt ttagagcata
     6481 atcgtgatgc tattaaggct agttttgcca gtccggctga aaaagaagct ttattggatc
     6541 gtttggaaaa ggcttatcag tcttacatca agaaataatg cttttcttgg caaagtatga
     6601 taaaatatac tgacatttag ttattttggg aggaaattat ggcattagcc aaaatcgttt
     6661 atgccagcat gacaggaaat actgaagaaa ttgctgatat tgttgctaat aaattgcaag
     6721 aattgggaca tgatgttgag gttgacgagt gtacaacagt tgatgcttca gagcttgagg
     6781 ctgctgatat ggcaatcgtt gcgacctata cctatggtga tggggactta ccagatgaga
     6841 ttgtcgactt ttatgaggac ttgcaggatt tggatttgtc aggcaagatc tacggtgtcg
     6901 tgggctctgg tgataccttt tatgattatt tctgcaaatc agttgatgat tttgacgaac
     6961 agctcgctgc cactggtgcc actaagggag ctgactcggt taaggttgat ttagctgctg
     7021 aggaagagga tattgctcgc ctagaatcct ttgctgagca aatgtcacag gcattagagg
     7081 cataagtaag acttttgata cagattggta aaacggtcag tggaggcttg cgttttttac
     7141 caccaaatgc atgaaaaact gatattttct gatcgttttt tcatgactat gtgctctttt
     7201 tcaagaaaag tcatgccatt attagcctga atgcaaacaa ttgatagtgt caaaatgttg
     7261 atcatatagt aaaaaaatgc atgtgactag aaagcagtta catgcatttt cgtcatgcgt
     7321 ttgtcgtgag gcattttggg ggttacttgc ttactgagct gaaattcact ataataaaaa
     7381 gataaataaa gaaaagaaga agttaggtga atgatgggat tagagaccat acgacaagac
     7441 attaatgctg ttgatcgtca gttgattgct ttgctggaaa agagaatggt cttggctgac
     7501 caagtagcgg cctataagca ggtacatgat gtgccagtgc ttgatcaaga gcgagaggct
     7561 gaggtcctaa ggagcgtgtc acagcagatt cggcataagg cctttgagcc tgccattctt
     7621 gagctattta agacaattat ggcagtatca aggcgttatc aggctgagca aatagcggtt
     7681 ggttcaaatg atgatgaagc ctattaaaaa caatcaagac atcagtatag gtgataatgt
     7741 ctatttggct tttgcagccc tgctcgttgg ggtggtggta ggtgtgatag atactgtttt
     7801 tggacaaggc ttgttgctct tgtctgctgt tcgtgatgct catctcattt acctgttacc
     7861 ctgcttagct cttgctggac ttgtgattgt gttcttatat gagcaatatg gccaaatcgc
     7921 taagcagggg atgggcttag tttttgatgt ggggcatggt gaaaaaacaa gactaccact
     7981 ggtgttgatt ccgttgatta tcctctcaac ctggctgacg catttatgtg gaggcagtgc
     8041 tggtcgtgaa ggcgtagcgg ttcaaattgg agcgacagtg tcacattttt ttggacgtct
     8101 tagacatctt aaggacaagt cacagctgtt tttagtcatg ggaatggccg caggctttgc
     8161 gggcttattt caaacgccaa tgacagcggt tgtttttgcc ttagaggtcc tgttgctagg
     8221 aaatataagc tatttagcct tgctaccttc tcttatagca gcctttaccg cctcttggac
     8281 ctctcattgc ctaggcttag aaaaattttc agtcccgata gccaaggcct tgaaaatcac
     8341 cccgataacc tttgggaaat tagtgctact aggccttatt tttggcttgg ctggtaatct
     8401 ttttgcctcc ttgttagcaa gggctaagcc atacattgca gcaaggctgc caaatcctta
     8461 ttatcgtgtg ttgcttgttg gtggttttct atcgcttagc ctgctgctgt gccattacgg
     8521 gcgctatagt ggcctaggga ctaacttaat tacagcggcc tttagtcatc agcctattgc
     8581 taattatgat tggctattaa agctcttgtt taccattatc actctctcgg ctggctttca
     8641 gggcggtgag gtcactccac tttttgctat tggtgcggct ttaggaattg tcctagcacc
     8701 atggcttggc ttgccggctc agttggctgc agcccttggc tatgctgcgg tatttggcag
     8761 tgccaccaat acctttttag ccccgatatt tgttggatta gaggtttttg gtgcaacaaa
     8821 cgcaactgct tactttatcg tgatagcctt tgcttatatg gtgagccgaa ggcattcaat
     8881 ctacactaag caaagggtga ccactagcat cgcttcctag tgtcttggtc agttttttgg
     8941 agaaaatagc tttacaagtg gggcttattt tgttacaata ggctccgtgt gtaatggacg
     9001 cacaaaaatt acggctaatc cgctaagact cgcgcttaag attagtaaga taaggagaat
     9061 aaacaatgaa tccattaatt caaagcttga cagagggtca acttcgtact gatattccta
     9121 gcttccgtcc tggtgacact gttcgtgtgc acgcaaaggt tgtcgaagga tctcgtgaac
     9181 gtatccagat ctttgaggga gtagtcattt cacgtaaaag tcaaggtatc tcagagatgt
     9241 atactgttcg taagatttct agtggtatcg gtgtagagcg taccttccca attcacacac
     9301 cacgtgttga aaagattgag gttgtgcgtc atggtaaggt tcgtcgtgct aagctttact
     9361 acctacgtgc cttgcaaggt aaggcagcgc gtatcaagga aattcgtcgc taaaaagagc
     9421 atacgagagg tttttcactg tcttatgaaa ggactgctgg agcagcaggg tctttgggac
     9481 aagctttttt tcgcaggtat gtgaacctac gctcaattca agacatatca aaggctcatt
     9541 ctatgataga gtgggctttt tgattgtgat catgctttag tgcctaaata aatgacagca
     9601 gcctgactaa tgaaaggctt acttgacttt ggaaatgctc aaggcttgcg ctaccagata
     9661 gaagctgaca tcatgccata gcagtcaagg ggaagaagga ctagattttt tggcgaggtg
     9721 ttgatctgtg accctgatgt tgttgggaat atgagagtaa tttaaaattt cgtcttgcat
     9781 tctacctttt tctaggttac aatagacaag taacctgatt agtgaagcta aaagacgtag
     9841 cgatgggttc taaaaaagaa tgattctggc gtttttggct aacctaagct gatagctttg
     9901 ctaggcagtg tcttagtcat ctggtcagtc ctgctagttt aacggataaa acaagcgcct
     9961 cctaagcgct agctgtgggt tcgattcccg cgcgggacat taaaaacaaa gtaaaaagag
    10021 tctgagaagg tttgagctgc ccctaattgt tagatttttt tctaactctt gaagtgtggg
    10081 tcaaagacta tttgtctcag gactcttttt aattggtttt tactaagctg cttcatctag
    10141 ttcttcagtt gctaagttgt ttccttcttc tgtatgttgg ttttcatcaa gtagcattcc
    10201 tgtgcggtaa tctaatgctg ccaaaggtga tacattatcc agaacaactg aggttatacc
    10261 ataatgatca acggattctt tgttgcctcc caatttgatt tggaggagct ctccgttttg
    10321 atcaattcca acgtactgta acactacttg acgaggaact aattcatcat tctgataaat
    10381 aggagttacc ttataatcta gccaaaagtt agggtgtatg gctaaccaat tgtctagtct
    10441 attttcataa taaagcattc ctaaaggatt tttatcacta aaacctgtat taaggtattt
    10501 tgtcatagta actaaatttt tgggttcatc atttaggccg ctaaactgat aaccgactag
    10561 atgtccgcga tccattaacc aagtcttttt ccctctagaa ttaatgactt gatagttatg
    10621 ccagccggga ggattaaatc taagcgcttt tcttttgaga gttggttcat cttgatcttt
    10681 gagttgtatg tgtgcatagg tggctctttg taaatgatca agatctccca gagctatttg
    10741 gtattttcca gtaaacggta aaattcctgg tatttcggta gcttttgttc ccaatgatat
    10801 ttccgttgta tctgggaagg ttctaagttt tcttgcagat tgaacagagt tagctgtgaa
    10861 aatagtcaga atagttaaca aaacaattgt tagacttttc cagttacggc gacgtgattt
    10921 agacatatca atgccctcct ttttttgttt acgagttaag tatatcactt ttaattaaaa
    10981 aaactt
//
LOCUS       DARYMD010000062        10977 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYMD010000062 DARYMD010000000
VERSION     DARYMD010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10977
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(32..1213)
                     /locus_tag="TU818_001693"
     CDS             complement(32..1213)
                     /locus_tag="TU818_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL0924486.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNRPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLAAK
                     PASTAAAAKKQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
     gene            complement(1297..2532)
                     /locus_tag="TU818_001694"
     CDS             complement(1297..2532)
                     /locus_tag="TU818_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL0924487.1"
                     /translation="MKKLIVTLAALMCLITNTSFAENFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLEAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKALP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMIATAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFNSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIGILINP"
     gene            complement(2854..4092)
                     /locus_tag="TU818_001695"
     CDS             complement(2854..4092)
                     /locus_tag="TU818_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL0924488.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQAGKLKWDSSVTISNYPYKLTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQVQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKVP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            4400..6376
                     /locus_tag="TU818_001696"
     CDS             4400..6376
                     /locus_tag="TU818_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0924489.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLSDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSVLAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKSLRSTLVPPTFVKIGDKNFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQKDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            6440..7939
                     /locus_tag="TU818_001697"
     CDS             6440..7939
                     /locus_tag="TU818_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0924490.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPSVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            7939..8865
                     /locus_tag="TU818_001698"
     CDS             7939..8865
                     /locus_tag="TU818_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0924491.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTI
                     LMLVILIAIILMSFIYPMFANYDFGNVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLIIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            8874..9944
                     /locus_tag="TU818_001699"
     CDS             8874..9944
                     /locus_tag="TU818_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924492.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGAPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            9937..10860
                     /locus_tag="TU818_001700"
     CDS             9937..10860
                     /locus_tag="TU818_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924493.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQSEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQVEAERYRKEL"
BASE COUNT         3249 a         2139 c         2281 g         3308 t
ORIGIN      
        1 taccaagaag tctttttaat cagcaatgag cttaacgtcc catcataaag gccatcagag
       61 caagtagtaa aacaataagg ataaaaatgg ctaagcaaat caagacaagg ggacgatgat
      121 catcgacaaa ttgttctatt ttttcaagaa atgattgatc agttgtggct tgtggcaact
      181 gctttttggc agctgctgct gtgctggctg gtttagcagc aagcctttta agcttgcttc
      241 gttttgcttt ggtgagtgtt ttactatctt taaaggcttt ttcagtcaaa gcattaatga
      301 atgggtgacg gtaaaattct ccattttggt cagaccaatc accaactcct aggacaactg
      361 taatcagtct ggtatttcct cgttttgctg ttacgaccgc attgaaagca gcacttgggc
      421 tggatcctgt tttcatacca tcaacaccct ctattccaaa cttaccatca ggcagagagt
      481 ggttgtagga atggaactct tcctcataag gggttccaac catggtgcgg acgacagttt
      541 gattggtaaa atcaagaata ctaggataat tggtcaaaaa ataataaatt aaggttgcaa
      601 aatcacgtgc tgttgtgata ttagaagctg ttaaatcata tttttctggg agatagtagc
      661 cttgaaaggc ttgtgcgatt gctccgctag catttgaaaa atgcgtatta gtcatgccga
      721 gctctttggc tgttttgttg atccgatcaa taaaggctga cgcatcgttg ttggataggt
      781 agttggcaat catcactgtt gcagcatttg atgacggaac cactgtcata atgattaaat
      841 cacgaatagg gtacgcaact cctgcaacaa tattattatt gctgatttcg taaattttac
      901 taatcgcctg atcagtctct gttgctgtaa tggtggtatc aagtgttacc tttcctttgg
      961 ccaattcctc aaagaggata taaagcgtaa acatctttga catactagca gggtctctag
     1021 gcatgtcaat gttatcctgc cataagatct ctgaggtctt tgcgtcaaca acaatggagg
     1081 cttttggcct attaacctca ctaacggtat agccagcctt gcgggtaatt tccatgacat
     1141 cttcggcgtg aacctgagaa atgcctagaa agcacaggca caccaaaacg aatagtagca
     1201 atcttttagt caattcaaag ctccttaatg taaaaaaata atgtaagctt attatatcat
     1261 ttcaataata caaatgaaat atattttttg aaaatattaa gggttaatga gaatgccaat
     1321 gactttttga aaaaagtcaa ataatttgct aagtttccct ttttcaggaa tgcttttagc
     1381 tgagacaata gcaacagctg gcggtgctgc tagatagcca ctgtcaatga gcttaggatc
     1441 ctgatagata agggtaccga cctttttatt ttgacgaatt ggggccttga gtgctttgtc
     1501 tttgattcgt agcgagtaag acagctctgt ctggtcctta ggccgaacaa ccgttaaggt
     1561 ttgactagcc ttgaccctta gcctttgctt tgctgcttgt ttaacaatca gtctttcagg
     1621 caaaacttgg ttttgagcaa caagcttttc caaggcatag ctattaaagc aataatcaag
     1681 caggcgattg gtctcaacaa agcgagctcg ctcatcagtg tcagattgat cagcatggag
     1741 aatgacagaa ataactcgca tattatcctg cacagctgtt gcaatcattg tttgtccggc
     1801 ttggctggta gtgcctgttt taaggccatc aaccccagct ctgcccatct cgcgaccggc
     1861 taatagtaga ttagaactag gcaaggcctt ttcaccccat ttcaattggg gctgtgagga
     1921 gatggtgaga agctcaggaa agtcttgaat caactgctgt gcaatcagtg ccagatctct
     1981 agctgtcatc tgattttcat catctggctg tgagcctgga tatagatgcc cctttagcat
     2041 actgttgttt agccctgaag cattgacaag aagatagtct ctaatccccc aagcctccag
     2101 ctgttttttc atcatgtcta caaatgtagg ctctgagcca gcgatatgct ctgctagagc
     2161 tacagcagag ctattagcac taataatcag gctagattca acaagctctt tgatagtgta
     2221 aggtctttgc tcaaatgctg ggttgctgat atcaggatca gtggctaatt gcagagcata
     2281 ttcagatagg gttacctgac tatcccactg gagccgtcct gccttaattt ccttcaggac
     2341 taggtagacg gttagtagct ttgttagaga agcaatgggc gccttttgct gggcctcttt
     2401 ggcatatagg atttttccag ttgtcatttc aaccgcaatg gcttgacgac tattaacaga
     2461 gaagttctca gcaaaggaag tatttgtgat cagacacatg agcgcagcaa gtgtcacaat
     2521 aagttttttc ataccatcat tgtagcaagg aaatagtgat cggtcaaaag gtcattgagt
     2581 acctttaaag aaggctaagt caagactctg agtgagatga cgtccccaaa aatcaagcct
     2641 caaaaaaacc gtctgacatc aacagactaa agctgtcaat tcatacggtt ttgctgtttg
     2701 cagagctttt gtaggcctta gagcttgcta ggagctcttt tagctacctt cttggagagc
     2761 ttgacacaat ggtcaatttt tgcgagataa gcctaatgaa gccctgagtg aggccttggc
     2821 actaatgagg acataaggca taaaagctag tcattagaga tattggttaa cataacgaac
     2881 aaaatgattc caccagacct ttaaaaagaa gctttttggc accttttttt gagccaccag
     2941 ctcaacgctt ggcgcttgac ctagatagcc ttttccgatt aagctatgat cattaagtgt
     3001 ggcctttgcg agtgtttgtc ctttttggat aggcgctact aagggatttt tggtatcgct
     3061 tacttgaaaa gtcgttttgg acttgtcgtc aagcgctttt atcatagtga gcttcttttt
     3121 tggcactagc tggatcttct tttgaggact atctaaaaca ggaagcgctt taagctgatc
     3181 tggtttaccc ttttcaagga caacaacctt tttaaaatgc gtcaaaacat actgcagcaa
     3241 ttggtttgtc gctgtaaaga cggccgtatc gttgtcctgg gcatggtcag cattgaggac
     3301 aactgtaata atacgcatat tgttttcgac actagtggct aaaaaagaag agcctccctt
     3361 ttcagaatag ctaacaaaaa gcccatcaac accatcacga tagttaggca ttccctttag
     3421 catatagttg tatgaaaaaa tctgttgatg attaaactca gcttgaacct gacttgatag
     3481 ctttaaaacc tcaggaaatt cctttaaaag atggctagtg acaagagcaa gatcggctgc
     3541 actaaattga ttatcatcat caagactaga tcccggatag atatgctctc ctagtatgtg
     3601 gttaggcagg ccactagcat tgacgacctt ggcacctgta atgccccagt ctttcaattg
     3661 agcgatcatt ttatcaacaa acttagcctc tgttcccccg attttttctg ccagggcaat
     3721 agcagggcta ttagcattgg tgacaataag agcctttaac agctctttaa cagtatattt
     3781 tctagcatct aagggcacat tgcttatggt gtagttggtg gttagtttgt aagggtagtt
     3841 agagatcgtt acggagctat cccattttaa ctttcctgct tgcacctctt tgtacaccaa
     3901 ataagctgtt aaaaccttgc ttagagaagc cacagaaaca gtcttgtcgg cgtccttttc
     3961 gtatagaatc ttaccgctat caagctcaac agcaatcgca tgcttggcgc taatatcata
     4021 atgatcagcc tgtgctggat aggccagaca agatatggct aatatggtca aagctattaa
     4081 aacctttttc atttgaataa tccttctagt cgttttttta attataccat aatttttcaa
     4141 gaagcttgac taaacctctc agagaagaga gatcattatg agaaaatgct agctgttatg
     4201 atagcgataa cgaactgtat aaaaatagca aataatgtat cttaaacgtc atcagatcgt
     4261 caacagaaaa aatcttgcaa aatattcaga taattttgcg atcgctattt ccatcagcta
     4321 aaatttgtgg tataatagct ccaattaacc aatttcattt atgctgataa atgaaaaata
     4381 acgtttaggg gtgacttcta tgaagaaaag taaatggttg gcaacgctgg gtgtcgcagc
     4441 gctgtcggtg tccatcctgg cagcctgtgg aaacagctca agtaaaagca gtgaatcaaa
     4501 gatttatagc tatgtctatt ctagtgatcc aagtacttta gactatatca gtacaagtaa
     4561 agcaacaaca aatgacataa caacaaatgc tgttgatggg cttttggaaa atgaccaata
     4621 tgggaattta atcccctctc ttgctaagga ttggaaggtc tcaaaggacg gcttgaccta
     4681 tacctacacg cttcgtgatg ggattaagtg gtacacatct gatggagaag agtatgcaga
     4741 tgtgacagct gaggattttg tagctggagt aaagcacgca gcagatgtta actctgatgc
     4801 cctatatatc attcaggact ctattaaagg cttaagcgat tacttgaacg gtaagaccaa
     4861 ggacttttca accgtaggtg tcaaagcgct tgacaaaaaa acagttcagt acacccttaa
     4921 tcaaccagaa agcttctgga attcaaagct aacctatagt gtcctagctc cggtaaatgc
     4981 tgacttctta aaatcaaagg gcaaggattt tggtaaggca acagatccat catctatcct
     5041 gtataatggt ccatttctta tcacagcttt gacaagcaaa tcctctatcg agcttgtcaa
     5101 aaacgaaaat tattgggacg ctaagaatgt tcaccttgat ggtgttcaat tgacctttta
     5161 cgatggacag gatcaggagt cattgtttag aaactttgat gacggtgctt actcagcagc
     5221 gagattattc ccaacaacac cttcttataa aactgttaag aaaaaatatg gagacagcat
     5281 cacttacgga caacaaaatg ctactctcta ctatgcggcg tttaacctaa atcgtacgtc
     5341 ttacaaccac actaagaaga cctcagatag ccaaaaatca gatacccaaa aggctatctt
     5401 aaacaaggat ttccgtcagg ctatgacatt tgcctttgat agaattgctt atcaggcgca
     5461 atcagcaggt gaagatgcag ctaacaaatc gcttcgtagc acacttgtgc caccgacatt
     5521 tgtgaaaatt ggcgacaaaa actttggtga tgttgttgag gagcacttgg tgacctatgg
     5581 tagccagtgg gaaaatgtaa atctagatga tgcacaggat ggcttgtaca atcctgaaaa
     5641 ggcaaaagca tcatttgaaa aagcaaaagc agccctacaa gctgagggtg tacagttccc
     5701 aatccatctt gattacccaa tggatcaaac tgcaacggtg ctcttacagc aggctcgctc
     5761 tatgaagcag tcaattgaga aaacattagg aactgacaat gttgtgattg atattattga
     5821 gcttcagaaa gatgtttatg aaaatattag ttatctcgcc gaaactcctg ctcaaaatga
     5881 ctgggatatt tcaacggctt ctggctgggg acctgattat gtcgacccat cgtcatatct
     5941 tgatattttc aacccaacgc ttgcaaactc acaaacaaaa tcaattggac ttgagccagg
     6001 taaggatttg gccattgcta gtgcagctgg cttagacgaa tttacaaagc tagtgacaga
     6061 ggcaggcaag attactgatg atctcaacgc ccgctacacg ctctatgcta aggctcaagc
     6121 ggcattgaca gactctgcta tttacatccc gactatttca cttggtggaa caccacgtgt
     6181 aactaaagtg gtaccgtttt caggcgcctt tgcttgggct ggtactaaaa atgactttta
     6241 ttacaaatac gtcaagctac aagataagcc tgtaactgct aaacaatatg acaaagcatt
     6301 agccgagtgg aaaaaagaaa agaaaaaatc taacgaaaaa tataataatt ccctcgagaa
     6361 gcatattgaa aaataaattg atgttcatta agaactttct cttagaggag gaagttcttt
     6421 tgaactgctg gggactagaa tgaaaaaata catatttgaa cgcatattga ggtcgcttgt
     6481 ttcaatcctg ctggtaaccg cactaaccta tactattgtc tttaccttag tgccaaaaag
     6541 cttgattttt aagcaagacc ctaattacaa taaaatggtg acaacacctg ataagaaaac
     6601 caattatcta aatactgttt ttgaaaatat gggctatatt tcctattaca gcagtaaaga
     6661 actgcagaat aaggcttcaa agcttgatcc ttctgtaaca actgcaccaa ccaaggccaa
     6721 tgaaaaaata tatcaaaaat atattgcttc tgtcggtaat ggttggaagc ttgggcgctt
     6781 tacagaaagt aagggatttt atgccgttag agagattcca atctatgagc gcgtgtggaa
     6841 tttctttagc catttggttg tgattgatca cccatggaaa atcaaggatc caaaaaatcc
     6901 aaatctagag cgttatgtgc gaccagaaat tgaccctgct gttggtccag ccttagttgg
     6961 ctctggtact aagcacaaat acttgattta cttcaacaag caatttccat ttatccatca
     7021 aaatatcgta acctttgatt tgggagtgtc ctatccaacc tatgccaata ttccagttgt
     7081 tcaggttatc actcaaggac aaggaagaac acttcaaaaa gaggtcacct tcccaacagg
     7141 caaaacaaag ctgtcttcaa tcgatattta ctctcgaacc tataaaacac caagctcttt
     7201 agatagcaag gatattgcca attttggtaa gggtgatgct tataccaata cacaaaataa
     7261 ctatgcagag ccatctatga ttgcaaattc ctttaagatt ggtattgtcg gtgtcttgtt
     7321 gtcctatctt tttggtttgc caattggtat gctgatggct tattataaga atggctggtt
     7381 tgaccgcttt tcaacggctg ccacaacctt tatgttagcc ctgccaagca ttgcgcttat
     7441 ctatattgtt cgatttgtcg gttcttattt gggcttgcca gatacctttc cgctgctagg
     7501 agcaggagat gttaggtctt atgtgctgcc tgctcttata ttaggaattc ttggtacacc
     7561 aagtacagta gtttggttcc gacgctatat tgtggacttg caaggcagtg attttgttcg
     7621 ctttgcacga gcaaaggggc tttcagaatt tgagatttca aaaaatcatc tctttaagca
     7681 ggctatggtg cctattgtta acggtattcc acaagccatt gtcggaacaa ttgccggtgc
     7741 aaccttgaca gaaaccgtct ttgctttccc aggaatgggt aaaatgctga ttgattccat
     7801 aaaagctgct aataactcta tggttgttgg tcttgtcttt atttttgctg ttttatcaat
     7861 attagccttg ctagtaggtg atattcttat gacaatttta gatccacgta ttaaattatc
     7921 aggtaaagga ggtaagtaat ggcagcaatt gacaaaaata aattcacctt tgttgaatta
     7981 gatagctatg catcagaagt cattgatgcc cctgcttact cttattggaa atctgtattt
     8041 agacaatttt tctcacgtaa atcaactatt ttgatgctgg ttattttgat tgctattatt
     8101 ttgatgagct tcatctaccc tatgtttgcc aactatgact ttggtaacgt gagcaatatt
     8161 aatgattttt caaaacgtta tatagcacct aatgcagagt attggtttgg tacggatcaa
     8221 aatggtcaat cgctctttga tggcgtttgg tatggtgcta gaaattcaat cttaatttca
     8281 gttattgcaa ccatcatcaa tatgattatc ggagtcattg tcggtggtat ttggggtgtt
     8341 tccaaagcag ttgataaggt aatgattgag gtgtataata tcatctctaa cctgccgcaa
     8401 atgctcatta tcattgtgtt gacttattct atcggagcag gcttttggaa cttgattttt
     8461 gctttttgtg tgacaggctg gattgggatt gcttattcga ttcgtgtaca aattttgcgt
     8521 tatcgtgatt tagaatacaa tttagcaagt cagaccttag gaacacccac ccataaaatt
     8581 gtcattaaaa atcttttacc tcaattggtt tcggtgatcg tttcgatggt ttccttgcta
     8641 ttgccgtcct atatttcatc agaggccttc ttatccttct ttggcttggg attaccaatc
     8701 acagaaccaa gcttgggtcg attgatttca aattattcaa acaatttaac aacaaatgcc
     8761 tatttattct ggattccatt gacaactctt attcttgttt ccctaccttt atacattgta
     8821 ggacaaaact tagcagatgc tagtgatcca aggacgcata gataggagaa gtcatgactg
     8881 aaaaacaaga aattatatta agtgctaaaa atattgttgt agagtttgat gtgcgtgatc
     8941 gtgtactgac cgctattcgt gatgtttctc ttgatttgta taagggagag gtattggctg
     9001 ttgttggtga gtcaggctct ggcaagtctg ttttaactaa gacatttaca ggaatgctgg
     9061 aggcaaatgg acgtgttgct tcagggacga taacctatgc aggtcaagaa ctaacagagc
     9121 ttaaaaatca taaggactgg gaagctattc gcggctctaa aattgccact atctttcagg
     9181 acccaatgac tagtctagat ccgattcaaa cgattggcag ccagattact gaggttattg
     9241 ttaagcatca gaaaaaatct agatcagagg ctaaggcttt agcaatcgac tatatgacaa
     9301 gggtcggtat tcctgagcca gaaaagcgtt ttggagagta tcctttccaa tattctggcg
     9361 gtatgagaca gcgtattgtt attgccattg ccctagcttg taagccagat attctgatct
     9421 gtgatgagcc gacaacagct cttgacgtta ccatccaggc tcagattatt gacctattaa
     9481 agacgcttca aaaagagtat cacttcacca ttatctttat cacgcatgac ctaggagtgg
     9541 ttgcaagtat tgctgataag gttgctgtta tgtacgcagg ggagattatt gaatacggaa
     9601 aggttgagga aatcttctat gatcctcgtc acccctacac atggagctta ttatctagcc
     9661 taccgcaatt ggcagatgaa aagggcgttc tgttttcaat tccaggggca cctccgtccc
     9721 tatacaagcc aattgttggt gatgcctttg cgccacgctc tcagtatgct atggccattg
     9781 attttgaaga aacagttcct cgttttacga tcagtgacac gcactgggca aaaacctggc
     9841 tcctacaccc agatgctcct aaggttcaaa aaccagctgt tattcaggat ttacaccaaa
     9901 aaatattgaa aaaaatgtca cgccaggagg aaggaaatgt ctgaaaaatt agttgaagta
     9961 aaagacctgg agatttcctt tggagaggga aagaaaaagt ttgttgccgt taaaaatgcc
    10021 aatttcttta tcaataaagg agaaaccttt tctcttgttg gagaatcagg cagtggaaag
    10081 acaacaatcg gtcgtgccat cattggttta aatgagacaa gttcaggcga aatccgctat
    10141 gatggtaaga ttattaatgg taaaaaatca aaatctgaag ctaatgaact gattagaaaa
    10201 atccaaatga tttttcagga tccagcagcc agcctgaatg agcgtgcaac ggttgattat
    10261 atcatctcag aaggccttta taattttaac ctattcaaga cagaagatga acgtaaagaa
    10321 aaaattaaac agatgatgtc agaggtgggc ttgcttgcag agcacctgac acgctaccct
    10381 catgagtttt caggtgggca gcgtcagcgt ataggcattg caagagcgct tgtaatggat
    10441 ccggagtttg ttattgctga tgagccgatt tcagctcttg atgtatctgt tcgtgcccaa
    10501 gtcttgaatc tgttgaagaa aatacagtct gaaaaaggct tgacctattt attcattgct
    10561 catgatttat cggttgtgcg ttttatttca gatcgtattg ctgttattca caaaggagta
    10621 attgttgaag tcgccgaaac agaagagctt tttgttaacc ctgttcaccc ttataccaaa
    10681 tctctgctgt cagcagtacc aattccagat cccattttag agcgtcaaaa gaaattggtg
    10741 gtttatcatc cagagcagca tgactattct gttgacaagc catcaatggt ggaaatcaaa
    10801 ccaaatcact tcgtctgggc taaccaggtg gaagcggagc gttaccgcaa agagctttaa
    10861 gattagttat catcacataa cagaatttag cctcagctag attctgtttt tgccttcctt
    10921 gggtagtctt ttttgttctg acaaggatag aaatatccag cattttccat ctattta
//
LOCUS       DARYMD010000063        10944 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYMD010000063 DARYMD010000000
VERSION     DARYMD010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10944
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..255
                     /locus_tag="TU818_001701"
     CDS             <1..255
                     /locus_tag="TU818_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL0924494.1"
                     /translation="QFTRAGIIENLIFKGFVERDKKNLIATHKGISLVAIVADNFKSA
                     ETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTYSK"
     gene            339..518
                     /locus_tag="TU818_001702"
     CDS             339..518
                     /locus_tag="TU818_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEL0924495.1"
                     /translation="MKDTFIDTAKVMSKGQVTIPKRIRELLNLENGDYVTFVVNKDRV
                     EIQNSNVFIEENIKK"
     gene            537..1964
                     /locus_tag="TU818_001703"
     CDS             537..1964
                     /locus_tag="TU818_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL0924496.1"
                     /translation="MTIDEIKKLIQAGEKIDVEFKESKNALTKDVFDTVCSFNNRNGG
                     HILLGANDKREIVGVSEDKVDKVIKEFTTAINNPQKMYPPLYLLPETFEIEGKQVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYPNLDIDFL
                     DASVIDKAKKMAVFRNKNHVWENMSNEELLRSANLILTDPETKREGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDERITVENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGQNPLFEEGDIFRTIIPLKKIA
                     TQKVGGDNVAHDVAQGVAHDVAHDKIALAEFIKEKVRSNDRITRKAIADEAGVSVKTI
                     ERAIKEIDNLKYVGSGNSGHWELNE"
     gene            2136..8966
                     /locus_tag="TU818_001704"
                     /pseudo
     CDS             2136..8966
                     /locus_tag="TU818_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            9476..>10944
                     /locus_tag="TU818_001705"
     CDS             9476..>10944
                     /locus_tag="TU818_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
                     /protein_id="HEL0924497.1"
                     /translation="MRTAKTILTVIHERGKQDKPLERVYKLLFNRELYLIAYAKLYPN
                     NGAMTKGVTEETIDGMSIQKIDMIIEQLRQETYYWRPARREYIPKKNGKHRPLGIPVW
                     SDKLLQEVIRMILEAYYEPQFSEHSHGFRPKRGCHTALQEIQTWKGTRWFIEGDISSY
                     FDTIDHDVLITMLSRQIQDGRFIRLIKNMLEAGYLDDWKFHKTISGTPQGGVISPLLA
                     NIYLHQFDKWVGEELIPQYTRGKKQKANSAYNRLSRRIKCYQDKGDYKKAHQLIVERR
                     NLPSVDTYDTSYRRLRYVRYADDFILGFTGSKAEAKAIKKQIGDFLNTKLSLELSQEK
                     TLITHATGESAKFLGYEIKAQRVNDYIDNKGRQSANGVIALFVPASVIESKCRQYMKN
                     GKAIHRNNLLHDDDFSIVQTYQQEYRGLVQYYILAQNLSWFSKVYWYMETSLLKTLAF
                     KHESSINKMLAKYKTTTTSTNGRTVPCLQVVVSREDKPPL"
BASE COUNT         3977 a         1598 c         2452 g         2917 t
ORIGIN      
        1 cagttcacaa gggcagggat tattgaaaac ttaatcttta agggatttgt agaaagagat
       61 aagaaaaacc ttatagccac acataaagga ataagccttg tagcgattgt agctgataac
      121 tttaagtcgg cagaaactac cgcaaaatgg gaaatggaat tatccgatat tgctcaaggg
      181 aaatcttcaa aggaagaatt tttagaagcg attgaaaatg agataaaaga agcggtttca
      241 acttatagta agtaagatga cactaatttc agagtagaaa aaatatctta aaagtgctat
      301 aatcttttgt aggaaaagta gggcgaaagg gattagtcat gaaagataca tttatagata
      361 ctgctaaagt tatgtcaaaa ggacaggtta ctattccaaa gaggattagg gaacttttga
      421 atttagaaaa tggagactat gttacttttg tagttaataa agatagagtt gaaattcaaa
      481 attccaatgt ttttatcgaa gaaaacatta agaaataaag gtggtgaaat aaacagatga
      541 cgatagatga aattaagaag ttaattcaag ccggagaaaa aatagatgtc gaatttaaag
      601 aatccaagaa cgctttaacc aaagatgtct ttgatacagt atgctctttc aacaatagaa
      661 atggcggaca tattttactt ggtgcaaatg ataaaagaga gatcgttggt gttagtgaag
      721 ataaagtaga taaagtgatt aaggaattta ctacggcaat caacaatccg caaaagatgt
      781 atccaccact ttatttgctg ccggaaactt ttgaaattga ggggaaacaa gttatttata
      841 taagagttcc tgaaggttat caggtatgca gacataacgg aagaatttgg gataggtctt
      901 atgaagggga catcaatatc acagatcatt cagagcttgt atataagcta tatgcaagaa
      961 aacaaggaag ctattttgtt aataaggtat atccgaatct tgatattgat tttcttgatg
     1021 cttctgtcat tgataaagct aagaaaatgg ctgttttccg aaataaaaat catgtttggg
     1081 aaaatatgag taatgaggag cttcttagaa gtgccaattt gatactgaca gatccggaaa
     1141 caaagcgtga aggaatcaca ttagctgcta ttttgttatt tggaaaagat aactctatta
     1201 tgtccgttct tccgcaacac aaaactgatg ctatattcag ggttgaaaat aaggatagat
     1261 atgatgatag agatgttgtc ataacaaatc tgattgacag ctatgacaga ctgatagaat
     1321 ttggacaaaa gcacttgaat gatttatttg tcttggacgg aattgtcaat gtcaatgcaa
     1381 gagacaggat actcagagaa atagtttcca atacgctggc tcatagagat tattcaagtg
     1441 gttttcctgc aaagatgatt attgacgatg agaggattac agttgaaaac agcaacttgg
     1501 ctcatgggat gggagcttta gatttacaga agtttgagcc atttcctaaa aatcctgcta
     1561 tatctaaagt ttttagagaa ataggtcttg cggatgaact tggttcagga atgcgaaata
     1621 cctacaaata cacacagctt tattcaggac aaaacccgct atttgaggag ggagatatat
     1681 tcagaacgat tattcctcta aagaagatag cgacacaaaa ggttggaggc gacaatgtcg
     1741 ctcacgatgt cgctcagggt gtcgctcacg atgtcgctca cgataagata gctctcgcag
     1801 agtttattaa agaaaaagtg agaagcaatg ataggattac aagaaaggct attgcagatg
     1861 aagctggagt tagcgtaaag actatcgaaa gagctataaa ggaaatagat aatctgaagt
     1921 atgtaggaag tggtaatagc ggacactggg aactgaatga ataaaattaa gttgcaaaac
     1981 aaagattttt ataaataaga gggtgctatg aataccataa aatgaggatt tgtagtagga
     2041 aatttaagtt gcagcaagtt gcaatacaca gaatcaaaag gtgattagag taaaatctaa
     2101 ccgccttttt tgtttggaaa aagaaggagg taaaaatgcg aataaatgat tttcataaca
     2161 ttttggagct tgtaaaacaa aatattttgc aaagtgaagc agaatacctg aagctcctaa
     2221 aggttgtcgg aaacaatcaa agatatgact ttagaagtca gttaagtatt tatgatagaa
     2281 attctgaagc gacagcctgt gccaagttcg actattggag ggaacgcttt aaccgtactg
     2341 ttatgagagg acaaaaaggt atccccattt tagaggacta cggcacatac aaaaaagtgg
     2401 catatatctt tgatataagt cagacggttt caagaaatag ggatgtcaat gaggtcaatc
     2461 tttggagatt tgataaagaa gctcataggg atgtcttaaa ggaaatgata aaaaacgagg
     2521 gctatgagga aagtgaaagc accttagaaa atatcttttc tttaagtaga ctctacggtg
     2581 atgaaaagat agacagcctt atgaatgagc ttagaatagc tgatgaggat agaatatctt
     2641 ttaccaagtt tgtgagggac tcagtgagtt atgcagtagc ttcaagattt aatgtagact
     2701 atcctatgga taatgagctt ctaaaggaaa actttgcaat gcttgatagc atttccctta
     2761 tgagtcttgg tgaaatcgta tcggatatta gtggaaagat tattgatgaa accattcaaa
     2821 aaagcaaaga gcttgagctt caaaaagaag ttttaagagg aaaagaagca ggatataata
     2881 ggattaaaga aaaaattgag aaaggagata atgatgtact tcgacgagat gatcaggaaa
     2941 gaaatgaaaa tgagcgagtt ctccgaaatg gagagtacgg acgagataat agagaaaatc
     3001 agggagaata cactaaacag cttggaggaa cagacggact tcataaggga gtatccgaat
     3061 ccgacctacg cagtaatgag gctggattac ctttcagaga gcgaggagca gagccacttc
     3121 gagatgttag tggatctata caaggagagg aagctaacag gacacctgat ggatattcag
     3181 aaacaggcga tagactttat gaggacagag aagccgaaat tgatggtagc ttggaagata
     3241 gaggacgaga acgatccgca gtatggggcg atgatttcag ctctgaagga aatgacaatc
     3301 aaggaagtat taaaaattta aaagataata ctgagataga gataagagaa gctgaaaagg
     3361 cttctttttc tttacccgaa aattcatatg gacagatgag acttaccatt ccattaactc
     3421 agagggatat agatactgtc cttattaacg gaggaaatca cgatggaagt agacttcctg
     3481 ttatcgctga gttttctaaa ggaaaaagta atgaagaatt aggagaatac ctaaaagata
     3541 tatttagagg cggtaatgga ttttacattg atgaaagaga agtatcttcc tggtattcgg
     3601 ataaaggcat tcatttagcc tacgggacat ctgcaagaga agatactacg caaattttaa
     3661 gctggagcga tgctgcaaag aggataaatg agcttcttga taatggtgag tttgctacaa
     3721 atgtagagat ttctgaggct cctgattatg aaagagataa gatttcagag tccttatggt
     3781 atctaatgca tgatttaagc gaagaaggac aaggatattt tgaactattg aaaacaagtg
     3841 gaagaggctt tccggaagaa acaaaaagat tgtctgaagc attaaaaaat cccgactacc
     3901 taaaggaaac gatcaaagaa tacagcaggt ttttagaagg atacaaagaa aacagaaatg
     3961 tattaaggtt tcactatcac aaggtagata gcctttgtca gaggttacag gaacttgagc
     4021 tgtcacgaaa ggaatatagt accaatctaa cagagcttcc gaaggtaaag tccttcatta
     4081 cagaagatga agtccttgaa agtctttcaa gaggaagtgg cgtcgataga ggaaaagagc
     4141 gaattacaaa gtttttcaaa gaaaatcata ccttgcagga aaaagctaat ttcctaaaag
     4201 acgaatatgg cataggtggt agaagtcatg cagtatcggg ggcaatggga agtgatgaat
     4261 ggcatgatgc aaaggggctt aaattacaga agaataattg taatgatgtt tttcttactt
     4321 ggtcaagtgt ggcaaagcgt atagaggagc tgctttctaa aaatctgtat gaagaaaaga
     4381 aaatagaaag taagtcagag gtagaagaat caaaagagct acaatattat tctaaagata
     4441 atcctgaaaa cttaatgact gatgaaatgc ttgaaagagt gcctgagctt tacgcacagg
     4501 aagatgtagc tttagcggat aaagaggttc atgcagcata tattattcct ttccgttcta
     4561 actggacttg gtatatgacg gaatatgata gggaaagcgg tgatgccttt ggacttgtgt
     4621 taggatttga acctgaatgg ggatatttca atcttgaaga attgaaagaa ttaaatgctc
     4681 aaaggcttat tttagaggat tttccaaaga cttttagaga gcttaaagat acagaacttg
     4741 caaagcagat ggatgaacag gaacttcaat cagtctttaa cggagaactt agctttgaag
     4801 ataaagaaga acttgaaata tctgaagaag tggaagaaag agtagctgca acacctgttc
     4861 aggaaacact atttgattat ctgaaggaga aggaagaagt agagcttaac gaagaaaaga
     4921 aaagtatttc agatgaattt gcagttaaag agggcgatac cgtctatttt aatcatgaag
     4981 aatatactgt aagggaaatt gctgaaaata aaatcacaga aagatatgac ttatggcttg
     5041 atccgggaag aagtggaaac catcaaatcc ctattgtagc ctttacagat aatgaagatt
     5101 tattaagaca agtaagccct gaaagacctg cgtttatcgt tggagatgaa attaaataca
     5161 aggataaaga ctataccatc acacgctttg acgatatggg aaataatcta aagacggtaa
     5221 cggttaagga taataccgaa tatcttggcg gtatgataac aggctcagat gtaattcctt
     5281 atcgtcttga aagcgatctt gagagggtat ttgaaaatct gacatataaa aagcctgaaa
     5341 ctattgctaa agaaagtgaa ataaagaaag cagaagctca taacttcaag attacggaag
     5401 aaacattacc tgacaagtta tctccaagtg aaaggctaaa taataacctt gaagccatct
     5461 ctatgctgag tcgcatcgaa agtggacaaa gagagtttga cagtacagct caggaagttt
     5521 tagcaaggta tgtaggctgg ggtggacttg ctgatgtatt cgatgaagaa aaaggcggac
     5581 agtggaaaga agcgaggagc tttctaaagg aaaacttatc tcaggcagaa tatgaagctg
     5641 caagagaatc taccctaacg agcttttaca caccgaaaac tgttattgac ggcgtatata
     5701 agacactttc cgatatggga tttaagagcg gaaatatcct tgagccatca atgggcatcg
     5761 gaaactttat aggaaatctt cctgatgaaa tgaacaagtc aaagttttat ggtgtagagc
     5821 ttgacagtat aagcggtagg attggaaaac ttttataccc tgaaagtgat atacagatta
     5881 aaggacttga agaaacttct ttttccaata acttttttga tgttgcaatc ggcaatgttc
     5941 cctttggaga atacaaagta aatgacaggg aatacaatcg taataacttc cttattcatg
     6001 actatttctt tgccaagtcc attgataagg ttagaaacgg cggggttatc gcctttatta
     6061 catcaagtgg aacaatggat aaaaaggatg aaagtgtaag acgctatctt gcagcaagag
     6121 cagagttttt aggagctatc agacttccta atgacacctt taagggtact gccggcacag
     6181 aagtaacctc agatattatc ttcttaaaga aaagagatag cgtattagag cgtgatgaag
     6241 attggataca ccttgcggaa gatgaaaacg gtcttgtata taacaaatac tttgttgatc
     6301 atcctgaaca ggtacttggc tcaatgcgtg aagtaagcgg aagatttgga aaaactctaa
     6361 cttgtgaacc gatatcttat ttaggcacag agctaaatat ggcttcatta aaggatcgta
     6421 tcgagattgc aggagaaaga atttcaaaag atgccaagta tgaagaaata gagcttttag
     6481 atgatgaaat cacttcaatc cctgcaacgg atgatgttaa gaacttttcc tataccatta
     6541 ttgatgatga agtctattac agagaaaact cactgtttat caaaaaggaa gtaaccgata
     6601 aaaacaaaga aaaaatcaag gattatcttg agctgaatgc tgccttaaaa aatgtgattt
     6661 acaagcagaa agaaggtttt agtgaggaag aaatcaaggc ttcacaggaa aaactaaatg
     6721 aagtctatga ccgtttttct aataagcatg gctttgtaaa taatttaagc aatacaagag
     6781 ctttaaaaga ggatagcaac ttcccgcttg tttcctccat tgaaatcctt gatgaagaaa
     6841 actttaaggc aaagggagat attttctcca aaagaactat tacaaaggct aaagtcatag
     6901 atcatgtgga tacttcttta gaagcccttg tcttatcggt atctgaaaaa ggatatgtgg
     6961 actttgacta tatggaaggt cttacaggaa aagacagacc gactttgatt gaggagcttc
     7021 gaggggaaat ctacttaaat attagggaag aacaaaactt ttatagacct ctatccttta
     7081 accccgaaga tggagatttg ccttttgcct gtgccaatgg cagtaattcc tacaaatacg
     7141 gctatgtaac aaaggatgaa tatttaagtg ggaatatcag ggacaagatt gccatagtag
     7201 atagctatct atcaaagctc agacagacgg aaagagagtt acctcatctt ggctatgcag
     7261 aagatggtaa agaaaaagag ctgattagct atgagatgaa tcgtttggaa taccaaaagg
     7321 ctgagcttac aaaagttcta ccaaaggagc ttgaagcaag tgagataagt gttcgtcttg
     7381 gtgcgacttg gataccgatt aaagatattg aaaaatttat ttttgaaacg ctgaaaactc
     7441 cgggatatgc aagatgggat attaaggtta agttttcaaa cctgacaagt gagtggaata
     7501 tagaaggtaa aagtagggat agaggaaatg acctcgctga aatgacttac ggtacatcaa
     7561 gggtaaatgc ctataagctg attgaagatg ccttaaacct gaaagaaaca aaggtatttg
     7621 accagattgt aaatccggac ggctctaaaa cttctgtact aaataaaaaa gaaaccatgc
     7681 ttgcagggca aaagcaggaa ctactaaaag aagaatttaa gaactggata tttaatgatc
     7741 aggagagaag aaaccgtctt gtaaaactgt ataatgagcg ttttaactct atccgaaaca
     7801 gagaatatga cggaagtaat ctttcctttg agggaatgaa tactaaaata gatttaagac
     7861 ctcatcagag aaatgccata gcaagaagtc tttatggagg caacaccctg cttgctcatg
     7921 tggtgggcag tggaaagacc tttgaaatgg tggcttccgc aatggaaagt aaaagacttg
     7981 gaatgtgtag taagtccttg tttgttgtac ccaatcactt aacaggacaa atcggtcgtg
     8041 agtttatgca gctatatccg tcggcaaata tcatggtggc agataagaaa gattttgagc
     8101 cgaagaaccg taagcgtttt atcggtcgaa ttgccacagg agaatacgat gccgttgtta
     8161 tcgggcatac gcagtttgaa aaaattccta tgtctaagga atatcaggag aagcatatcc
     8221 aagatcagat tgatgaaatc gtaaactatg tagaagaata caagcatgac agaaatcaga
     8281 actttacagt aaaacagctt gaaaagacaa agaaaaaact ggaaacaagg cttgagaaat
     8341 taaatgacga ttttaagaaa gatgatgtca ttacctttga ggaattagga gttgataagc
     8401 tctttgttga tgaagcacac aactacaaaa atctctatct ttatacaaaa atgcgtaatg
     8461 ttgcaggaat cggtcaaagt gaagccttta agtcctccga tatgtttatg aagtgtcgct
     8521 atatggatga aatgacaaac ggaaaaggca ttgtctttgc aacgggaacg cctgtatcaa
     8581 actccatgac tgagctttac actatgcagc gttatcttca gtatgagagc ttaaagaaaa
     8641 ataatctgga gcattttgat agctgggctt ctacttttgg ggaaacgcag tctgcttttg
     8701 agctttctcc ggagggaaca ggatacagag taaagacaag attttccaag ttctataact
     8761 tgcctgaact aatgtctatg tttaaggaag tcgctgacat tcaaacagcg gatatgttaa
     8821 atcttccaac acctgaggca cattatgaag taattaagac cttgccaagt gaggagcaaa
     8881 aggaaattct aaagagcctt tctgaaagag cagatgatgt gagaaatagg gtggtagagc
     8941 ctgacaaaga taatatgcta aaaattgtgc gctgttaagc gtaaaaatgt atctccctca
     9001 cagagggata ttattgaaag taaataatag gaacaactaa ctaacctagc ggggaaaccc
     9061 aaaggggaca atagcatgtt agtaaagcgg ataaggagtg agttacaacg ctttgatgtg
     9121 ccgcaagttc cgtaacctat ggttaaggct aaactgcttg aacctcaatt ctgactaggt
     9181 gcaaagcatc gcccatcgga aagtaactga gaccgatgtt actgtatatt cgttgttgtg
     9241 attttggacg aataactttc tacagtaaaa gagcatacga taagtatgaa taaaggaatg
     9301 agtgaggaac ctaagggtta ctagaacgta catttttaac gaatagcagg attgcctaag
     9361 aggggggacc cttatggtaa cggagtcacc gtagtagtcc gagcaaggga aatccttgta
     9421 catggcgaag ggtgacaggt aatttcgatt agttagaaag gattaggtgc gtgggatgcg
     9481 tacagccaaa actattttaa cggtcattca tgaacgtgga aaacaagata aaccactcga
     9541 aagggtttat aagttactat ttaatcgtga actctatctg atagcctatg caaagttata
     9601 cccgaataat ggagcaatga caaagggtgt tacagaggaa acgattgatg gaatgtctat
     9661 tcaaaaaata gatatgatta ttgaacaatt aagacaagaa acctattact ggagaccagc
     9721 taggagagag tacattccta aaaagaatgg aaaacaccgt cctttgggaa taccagtatg
     9781 gagtgataaa cttcttcagg aagtgattcg catgatatta gaagcctatt atgagccaca
     9841 atttagtgaa cattctcatg gttttagacc aaaaagaggg tgtcatacag ctttacaaga
     9901 aattcagact tggaaaggga cacgttggtt catagaagga gatatctcta gttattttga
     9961 cacgattgac cacgatgtat taatcactat gttgtctaga caaattcagg atggtcggtt
    10021 tattaggctt atcaaaaata tgcttgaggc aggatatctt gatgattgga agtttcacaa
    10081 gactattagt ggaacaccgc aaggtggagt tattagtcct ttattagcta atatctattt
    10141 acatcaattt gataagtggg tcggtgaaga gctgatacct caatatacaa gaggtaaaaa
    10201 gcagaaagca aactcagcct ataatcgttt gagtagaaga attaaatgct atcaggataa
    10261 aggagattat aaaaaagctc atcagttaat tgttgagaga agaaatctcc cttcagttga
    10321 tacttatgat accagctatc ggagattaag atatgttcgg tatgcggatg actttattct
    10381 aggctttaca ggttcaaaag ctgaggcaaa ggctataaag aagcaaattg gagacttttt
    10441 aaatactaag ttatctttgg aactttctca agaaaagact ttgattaccc atgcgactgg
    10501 agaatcagct aaatttctgg gatatgagat aaaagcacaa cgtgtcaatg attatattga
    10561 taacaaaggg agacagagtg ccaatggtgt tatcgcatta tttgtacctg catcagttat
    10621 tgaaagcaaa tgccgccaat acatgaaaaa tggtaaagct attcatcgta ataacttatt
    10681 gcatgatgat gactttagta tcgttcaaac ttaccaacaa gaatatagag ggctagttca
    10741 atattatata ttggcacaaa atttgtcatg gttctcaaaa gtctattggt atatggaaac
    10801 atcactcctt aaaacattag catttaaaca tgagtcatcc attaataaaa tgttagctaa
    10861 atataagact accacaacta gcacgaatgg ccgaacggtg ccgtgtttac aggtagttgt
    10921 gtctcgagaa gataaacctc ctct
//
LOCUS       DARYMD010000064        10639 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYMD010000064 DARYMD010000000
VERSION     DARYMD010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10639
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..189)
                     /locus_tag="TU818_001706"
     CDS             complement(<1..189)
                     /locus_tag="TU818_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0924498.1"
                     /translation="MAIEVLNVTKKFGSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGKVLVDE"
     gene            complement(189..2171)
                     /locus_tag="TU818_001707"
     CDS             complement(189..2171)
                     /locus_tag="TU818_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0924499.1"
                     /translation="MKLKLCIVGFFFCLIAAIGLVSINDTQKPIPLPIDGAFSIQGKS
                     NLSNEEVYQTISDLSKEKKVTIYKPVVQNSGQLTYIKFDNTNHEQLKSAPITGMYYTL
                     GKLDSNSLKPLTSTGLQVIYLAYPWQIGGMIQFTGPLRLLLMISIYLTLLVVLFVVRA
                     RQIKEGVIRRSLGLPVHDLRRDYFMSFTFELVMAALLMISYSSFLGSGFFTYSSKLFF
                     SMLLTNLIIFQIIDIITFVLFWLTIKVEKPIEIIKNKAKNSLIFIVWLAVISIIIVVS
                     GVFLRETKASQSKINMQIKHLKPWSAVKDWKRPEFLGIENESVTNGEEANDSGAKYVE
                     IAKALKKLDFIYIKSSSAYVPEYMAASDVTEDFSKQLKSDGITHPEVNKELVYINQTG
                     AKVQNKVNGTNYQSLDNKIATIYIPHKFKENKASIENTVVAEQFTGTNYTKDDLTVQV
                     IPDGQEFFYFNENGSSVPENKDNLPLESVTDSKDNIVVVLDTDKMIENNDFILASNII
                     YNSLFSSEAIKKINDLSASLNFSINPVEVYQTVKLNIQSLEHQIFLSKILQIIICGIV
                     FLLIYQYAQMFVALKQNDYVKKIILGLSKTRIAISSLNYFIVTITMVILLTFMLTGQV
                     ELLYIGIASLMVLIFSTIMSFRKLSEKYTQILKGDD"
     gene            complement(2238..2543)
                     /locus_tag="TU818_001708"
     CDS             complement(2238..2543)
                     /locus_tag="TU818_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924500.1"
                     /translation="MLAVSTLSFGSAATARVVSAATAHPAPYPIIDEWNYGVSDNYGY
                     SNDYVKSPNNIGSKSSVTNLWGTVKDRDSQKYGWANSSATKSWNDVRLNTHWNYFTF"
     gene            complement(2710..3027)
                     /locus_tag="TU818_001709"
     CDS             complement(2710..3027)
                     /locus_tag="TU818_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924501.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKRAYQKREDSLSERRH
                     VLNDLINSEYQKMSVFLKRLDLSANAASDFFNELGRLKDQSNAEFHLFLKLGKILNNK
                     SLG"
     gene            complement(3009..4298)
                     /locus_tag="TU818_001710"
     CDS             complement(3009..4298)
                     /locus_tag="TU818_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924502.1"
                     /translation="MAISDSSYNELAKQVYNVEPSKAKSNGDLVIVAGKTVKDPITKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVKGDIDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKSMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKAAREGADEALDHK
                     TVADAKLMEVWSAIDFNSFHELPYYEVQALFASYGITYDRFVQDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDRQLAGEFRAWQTEL"
     gene            complement(4300..4743)
                     /locus_tag="TU818_001711"
     CDS             complement(4300..4743)
                     /locus_tag="TU818_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924503.1"
                     /translation="MMTVKTNKQRLWLGLIIVIGAIIMVFRLNGKRTEEQQKRDLETS
                     IAKLLVHDYEGVKEVKFTGWGHSRETGSWGTIVIINGENEIGFSFDGLSSLEKIRGIV
                     TDDDTEKMEKPETDTKPRIMDRIDKINKTSLVGVTVIYSKDNQED"
     gene            complement(5108..8659)
                     /gene="smc"
                     /locus_tag="TU818_001712"
     CDS             complement(5108..8659)
                     /gene="smc"
                     /locus_tag="TU818_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL0924504.1"
                     /translation="MFLKEIQMQGFKSFADKTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMPDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALVALREDLAAYHRKRQSLEAENHRLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSRQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQE
                     ADVSNQLTAIVAQLDKESQAKASQAQEYQVLQEKVNQLSQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTRLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAAAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGTNRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKENKDTIK
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQVSQ
                     EAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLAFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFKETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGISKVVSVKLKDTQDLTYLS"
     gene            complement(8660..9352)
                     /locus_tag="TU818_001713"
     CDS             complement(8660..9352)
                     /locus_tag="TU818_001713"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL0924505.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
     gene            9605..>10639
                     /locus_tag="TU818_001714"
     CDS             9605..>10639
                     /locus_tag="TU818_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634-like element ISSeq4 family transposase"
                     /protein_id="HEL0924506.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQMIKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFRDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKLG"
BASE COUNT         3056 a         2385 c         1879 g         3319 t
ORIGIN      
        1 ctcatcaact aaaacctttc cactgtcaat tttttctagt cttcctatga tattaagtag
       61 tgtactttta cctgaaccag agcctccaat caatgcgtag ctttttccag cttcaaacgt
      121 taaatttaaa tctgtgaata tcttttttga gccgaatttt ttggtaacat tcaaaacttc
      181 aattgccatt agtcatctcc ttttagaatt tgtgtatatt tttcagataa ttttctaaaa
      241 ctcattattg ttgaaaaaat taaaaccatt aaagaagcaa tgccaatata taatagctct
      301 acttgtcctg tcaacataaa tgtcaataga ataaccattg taatagtcac aataaaatag
      361 ttgagacttg aaatggctat acgtgttttc gataggccta aaatgatttt tttaacatag
      421 tcattctgtt ttaaggcaac aaacatttga gcatactgat aaatgagtag aaatacgatt
      481 ccacaaataa ttatttgcag tatttttgaa aggaaaattt gatgctctaa ggattgaata
      541 ttaagtttta cagtttggta aacctcgact ggattgattg aaaaattcaa actagcactc
      601 aaatcgttga ttttcttaat tgcttccgaa ctaaaaagtg agttatatat tatattactt
      661 gccaaaataa aatcgttatt ttctatcatt ttatcagtat ctagcacaac gactatatta
      721 tccttactat ctgtcacact ttccaaaggt agattatctt tattttcagg aacactacta
      781 ccattttcat tgaaatagaa aaattcttgc ccatcaggaa tgacttgcac cgtaaggtca
      841 tcttttgtat agtttgtacc agtaaattgt tctgctacaa ctgtattctc gattgatgcc
      901 ttattctctt taaatttatg aggaatatag atggttgcta ttttattatc taatgattga
      961 tagttcgttc cattaacttt attttgtacc ttagcacctg tttgattaat ataaaccagt
     1021 tccttattaa cttctggatg cgttattcca tcacttttta attgcttaga aaaatcttct
     1081 gtaacatcag aagctgccat atattctgga acataggctg aagatgattt gatatatata
     1141 aaatccagtt tttttaaggc tttagcaatc tctacgtact tagctcctga gtcatttgct
     1201 tcttctccat tagtaacaga ttcattttca atacccaaaa actctggtct tttccaatct
     1261 tttactgcac tccatggttt taaatgcttt atctgcatgt ttatctttga ttgactagcc
     1321 tttgtttccc gtaaaaagac tcctgaaaca actattatga tagaaataac cgcaagccat
     1381 acgataaaaa tgaggctatt tttggcctta ttttttataa tttcaatagg tttttcaacc
     1441 ttaatagtta gccaaaatag aacaaaggtg atgatgtcaa tgatttgaaa tatgatcaaa
     1501 ttagttaaaa gcatagaaaa aaataacttg gaactgtagg tgaaaaaacc actacccaaa
     1561 aaagaactat aagaaatcat caataaagcg gccataacca gttcaaaagt aaatgacatg
     1621 aaataatctc ttcttaggtc gtgtacaggt aatcctaaag aacgtcttat cactccttct
     1681 ttaatctgtc tcgctctaac aacaaataga acaactaata aggttaagta aattgaaatc
     1741 attagcaata atctcaacgg accagtaaat tgtatcattc cccctatctg ccaagggtaa
     1801 gccagatata tgacttgaag acctgtagat gtgagcggtt ttaaactatt tgaatctaat
     1861 ttccctaggg tataatacat ccctgtgatt ggtgcagact ttaattgttc atgattagta
     1921 ttatcaaact tgatataagt caactgcccc gaattttgaa ctaccggttt gtaaatggta
     1981 acttttttct cttttgatag gtcactaatc gtttgataca cttcttcatt agaaagattg
     2041 cttttccctt gaatggagaa ggcaccatca attggtaaag gtattggttt ttgagtatca
     2101 ttaatactaa ccagaccaat ggcagcaatt aaacaaaaga agaatccaac aatgcataat
     2161 tttaatttca taagcaccta cctatatcat aaaaggccct atagcattat tgggccttta
     2221 gctttcataa accattttta aaatgtaaag taattccaat gtgtatttaa tcgaacatca
     2281 ttccagcttt ttgttgcgct tgagtttgcc catccatatt tttgagaatc tctatcctta
     2341 actgttcccc atagattagt tactgaagat tttgaaccaa tattatttgg agacttaaca
     2401 tagtcattag aataaccata gttatcactt acaccataat tccattcatc aataattgga
     2461 tatggagctg gatgcgctgt tgctgcacta acaactctag ctgtagcagc agatccaaaa
     2521 cttaaagtgc ttacagcaag caaaactaat gttttgtcac caatttttca tattagttct
     2581 cattggatag attgttaaaa atatttgaac aatctaaata atatattatt atttattagc
     2641 ataatatcat attattattt gaattacaag atgctaaatt gcaagtaaaa gttagtcatc
     2701 ctatagaaat tatccgagtg acttgttgtt caaaattttc cccaatttta aaaagagatg
     2761 aaactctgcg ttggattgat cctttaagcg acccaattca ttgaaaaaat ctgatgcagc
     2821 attggcagat aggtctaaac gcttcaaaaa aacactcatc ttctggtact cagagttgat
     2881 caaatcattt aagacatgtc ttctttcaga taagctgtct tcacgcttct gataggctct
     2941 tttctggcgt agaaagtcct gctcggcatc atccatctcc cgaagcttac gataaatagc
     3001 cacttcctct acaattctgt ctgccatgct ctaaactctc ctgctaactg acgatccgtt
     3061 tcaagcttgc tatcaataac cgtctgaata tctctattca agttttcaaa gtctgtggcc
     3121 aaggctgaca gcttgctgac cttggattga gtatagtcct gaaagtcttg gacaaagcgg
     3181 tcatatgtga taccataaga agcaaataag gcctgcacct catagtaggg cagctcatga
     3241 aaagagttga agtcaatcgc cgaccacact tccataagct ttgcgtctgc aaccgtttta
     3301 tgatccagag cttcatcagc cccctctcga gcagccttag ccatggacga gcctaggatc
     3361 attccctgtg ccgcatctaa aaagagctcc tcagaactac tgatcccctt gccggtagac
     3421 tgccagtgtt ttttgagctg attgtagctt gacatgctct tttttgaggc aaggacagtt
     3481 aaataggccc gactcacaag gtattgtgtt ccaatgagct taccgtctct atctacaatc
     3541 tgaccctttt gattaaaacg ataagctcct aaatcgtgat aatacaaggg gttggctgat
     3601 aagagcatag catcgacatt ccgagaaata gctaaatcat cagttccaaa ataggcacca
     3661 aaattgccaa tgccatcaaa attaatgcgg aaattattgt acatattgct attagcctta
     3721 acccatgtga tagcttcagc tgacatgccg cgaacagggt ctggaccatt aaaggttgtt
     3781 gctgggatct tatgttctgc ggcaactatt agtgctagat aagctccgag agagtgacct
     3841 gtggttgtta aggcagaatg agggtacttt cttttgacct gttgataaaa cttttgagca
     3901 gatcgtaatt ggttttcggc aataacaaaa ttgccaccat caatattgcc gctgactaaa
     3961 tcatcttgat tgccccgaat gagcagctgc caatccgtat caagatctct ggaatccgca
     4021 gcatttgtcc ctgcataggc aatcacaacc tgagaggtat cgatatcacc tttaacaata
     4081 ggggctacag ccattgcctg cataccgttg tcattggttt tatgggcatc gttgttattg
     4141 tcctgaacta agaggactcg gtattgtcgt ttagtgatag gatcttttac agttttacca
     4201 gcaacaataa caaggtctcc atttgattta gctttgctag gttcgacatt ataaacctgt
     4261 ttagccaact cattataact actatccgat atcgccatat taatcctcct gattgtcctt
     4321 tgaataaatg acagtaacac ctacaagaga tgttttatta atcttgtcaa tcctatccat
     4381 aattcttggt ttggtatcag tttcaggctt ttccatcttt tctgtatcat catcagtaac
     4441 aattcctcgt attttctcaa gactagacaa gccatcaaac gaaaagccta tttcattttc
     4501 tccatttata atcactatcg ttccccacga acctgtttcc cgagaatgtc cccagcctgt
     4561 aaacttaact tctttaaccc cttcatagtc atgaaccagc agcttagcaa tactggtttc
     4621 caagtccctt ttttgttgtt cctctgttct tttgccattc aaacgaaaaa ccattatgat
     4681 cgctcctatt actattatta agcctagcca tagcctttgc ttattggtct taactgtcat
     4741 catgtcctcc tttcactctt ttgctatgcg tccgtcactc taaggaaggc agcatgacta
     4801 attagggtga aatcaacgcc aaatcttatt tatattattc tcattttgta attaaattat
     4861 aatatacaga catctacttg tcaatatatt atgtccttag ttactttttt ggtatatttt
     4921 aatcaaaaca agccgtacta agttccagga gcatgtcaaa aacagcagct tactgctagc
     4981 caatccttgt gctttgtcct ttggaaagcc aaaaaaccta ccatgacgat aggttttttt
     5041 atagcttatt cttggttatc atctgctaca tgtagaaata cagctaaaac taagctctgt
     5101 cctagagtta tgacaagtaa gtcagatcct gcgtatcctt gagcttaaca gatactacct
     5161 tagaaatacc agattcttgc atggtaatcc cataaatact gtctgctgct gccattgtcc
     5221 ccttgcggtg ggtaaccacg ataaactgac tatccttgtc aaaacgattg agataatctc
     5281 caaaacgctt gacattggcc tcatcaaggg ccgcctcaac ctcatctaaa atcacaaagg
     5341 gaatggtctt aatgcggata atagcaaata aaagggctag cgctgataag gctttttctc
     5401 cgccagacat cacattcaaa gattgaagct ttttaccagg cggttgcact gaaatatcta
     5461 ctccagcaga aagcagatca gtctctgtca acatcaagtc cgctgagccc ccgccaaaca
     5521 tctgcctaaa ggtctcctta aagctatcac gaatagcctc aaaggtaacc ctaaagcgtg
     5581 ccttaacctc atggtccata ttgccaatcg tatctaccaa gagattcttg gccttgataa
     5641 ggtcagccct ttgaccattt aagaaggcca aacgctcact aacctcatca aattgagcaa
     5701 tagcatcact attgattggg cctagggcac gaatgctttg ctgaacctgc tgcaatttct
     5761 gtcttgctgc tgccatgtca gtgtcattga ttgggcttgc ctgctccttg gcctcctcta
     5821 agcttagctg aagctcctct gataggcttc tagcgtgctg ccgcaaacga ccaataacct
     5881 gctctaagtc agcctccagt cttgcctgct gacgaatgaa cgcttcattt ttcttggctt
     5941 ccttaagcaa ttgagcctct agctcctcca gtctggcgtc atagtcctca ccttcaaagc
     6001 gcagctgaat gaagcgctcc tgagtcttga tcttgtcttg attagcctct gtcagctgat
     6061 tttctaggtg aggcaattgg tcaatggcct cctgactaac ctgatgtgat aaaacagtct
     6121 ccaaattagc taattccttc tgaccctgag caatcatcgt ctccaagcga cgctggttag
     6181 ctgcttcaaa ctttttctcg ttgagcaaat ctcgctcttt aagacgagcc tgagataatt
     6241 cctggctaag ctggtccttc ttttgcttaa tcgtatcttt attttcctta atttgctcaa
     6301 tttctgacgt taaggctgat ttttcatcag ctaggagctg caatgcctcc tccagcctcg
     6361 ctttttctga taataagcgc tcactagact gaccagtctg acggttgctg agaagctcta
     6421 gcagctcttt tgagtcagcc agcttttctg ctagctgctg ataggccaat tgtgtttttt
     6481 gctcgaccag tcttgcttgc tcaccagcca gcttagtatc agcctgcgca gcctttttag
     6541 ccttcaaatc agcctgtaca gcagctactg ctttttcaga ttccttgatc tgctcagaaa
     6601 gcaaggctaa ttccttctca atctgctcta gctctggctt gataaaggtt gtgctattgt
     6661 gacgattagt cccccctgaa aaggcaccac cgggacgcag ctcggtacca tcaagcgtta
     6721 caatcctgac cttataatgc agctgcttag ctgcctgatt agcatgatca atggtatcaa
     6781 aaatagccgt cacacctaac aggctttgta caatagcgac caaagagggc tcataggtca
     6841 ccaaagaatc agctgtgcct aaatagccct gacaagccct gagctgcttg agagtcacct
     6901 cagaaagctg acgggcctta atcgttgtca gaggtaaaaa ggtcgcacgc ccctgacgat
     6961 tagcctttaa aaaggctatc gctcgcttgg ctgctgcctc atctgccacg ataatatgct
     7021 gactactagc tcccaaagca atctcaagtg ccgtttgata ctgactatca aaggtcaaat
     7081 gctcactaac tgctcctaaa ataccatcta gcttaccagc agcctgaagc actgccctaa
     7141 cacctgcgta aaattgacta tgattttttt ggatagaaac caaactagcc ctacgagcct
     7201 ccttggcttt tttctgatcc aacaaatcaa aaagccttgt ctgtccctga tgataatcct
     7261 gctccaaggc ctcaactgtc tttgctagct cttgataatc agctaggagc tgctcaagtc
     7321 ttgattgact agcttgataa gccaaaagag cagtctgggt gtcctgactg agctgattga
     7381 ccttctcttg taggacttgg tattcctgcg cctgactggc tttcgcctga ctttccttat
     7441 ccagctgcgc tacaatagcg gttaattggt ttgacacatc agcctcttgc tggagcagac
     7501 caacaaaatc ctcacgaaga gcctcaagca gctgatctgg atcgctagaa aatcgctcaa
     7561 gctcctgaga aagctcgctg accttggtat taaactcagc taaggcttga tggatttcat
     7621 ctagctgacg actcttttgc tgatgctcct gttgaaaggc aagcaattgc tcctgagcct
     7681 gctgcctgcg ctgactggct tctgttttct tttcctgctt ttgactaagg tccagcttga
     7741 tgaggtcaat ctgtcgctcc agatctgata tgacctttgt caattctagc aaatcagcct
     7801 gcgtctgctc agctacagca gagagctttt gccgcttggt ttttagacgg tgattttccg
     7861 cctctagact ctgacgcttc ctatgatagg ccgctagatc ctcacgaaga gctactaagg
     7921 ccttttcttg agcctcctgc tccatgcggt cttgctctat atccttgacc aaaatatcca
     7981 gctgcagctg cttacgatca gcatctaagg ctaaaaattg cctagcagtt ttcgcctgtc
     8041 tttctagagg accagcttga tgctcaagct catagataat atcgtctaag cggtcaagat
     8101 tatcttgagt ttggtttagc ttagtttgcg tctccttctt gcgggtcttg tatttcaaaa
     8161 ctccagctgc ctcttcaaag atggcccgtc tttcctctgg cttactattg aaaatctcct
     8221 caacacgacc ttgagaaata atagagaacg aatcgcgccc tagtcctgta tccataaaca
     8281 gctcgtgaat atctcttagc ctaacttttt tgccatcaat cagataatca ctgtcgccat
     8341 tgcgatagat atgcctctcc acacgaatct ctttctgagc attcttaata aaggcatctg
     8401 aattatccaa gacaacagcc acctctgcat aattcaaggg actccgatgc tcagttccag
     8461 caaagatcac atctggcatc ttgccaccgc gcaggctttt ggcactggcc tcaccaagtg
     8521 cccaacgaag gctttctgtc acattacttt ttccagagcc atttggccct acaacagctg
     8581 tgaccccctt atcaaagata atcttggtct tatctgcaaa agacttaaag ccctgcattt
     8641 gtatttcttt taaaaacatt tagacctcac taagttgggc cagggcattt ttagcagcgt
     8701 cctgctctgc cagtttttta gatctacctg tccccttgct aagatgatcc tcaccaacca
     8761 atacagctac ctcaaattgc ttagcatgag ctggtccagt ctcgctaatc acctgataat
     8821 caatcacaac atcaccctta gcctgtaaca actcctgcaa gcaggtttta taatccttga
     8881 ccttctcaaa agttccctgc tcaacctgtg gaatcataac ctgatttaaa aagcgacgaa
     8941 cctcttcaat gcctttatcc aaaagaagag cacccaaaaa agcctcgaac aaatcgccta
     9001 aaatcgtatc acgatgacgg cctcctgatt tttcctcgcc cctgccaagc ttaatataag
     9061 catcaaacga acaatagcgt gaaaagcctg ctaagctttc ctctctgaca atcgttgatc
     9121 tgagttttga catatcaccc tcagtctgct taggatactt ggcaaagagg tattctgaaa
     9181 taattaactg tagaacggcg tctcctaaaa attccaaacg ctcattatgt gaaatgttta
     9241 ggaggcgatg ctcattagca taagaggtat gtgtaaaggc agtctctagt aatcttttat
     9301 catcaaaacg gatattaaaa gagttttcca gcagggcctc aagctttttc atcatgacaa
     9361 atctcctttt ctaatgtcct tataaaccat tctattataa caaaaatcca cttgaaaggc
     9421 ttatcacaag tggatttttc agaaatattg taccaaatag gcacgagcta ttgactgctg
     9481 ctatttcccg actttatcac ttgttttagt ccacacctta ctcaacccct tggtagagta
     9541 aggtttttta ataaatttta acgctttttc ttgttgtgta tggttatata tgttataata
     9601 aactatggct tttattaaaa caacaacgaa taaagaaggt aggacgcatg tctaccttgt
     9661 agaagggtat cgtaaagatg gtaaggtcaa acagcgtatc cttaaaaaat ttggtctctt
     9721 agatgagctt gaattggaag aaccagggat tcttgagcgt cttaagcgcg aagctaaaga
     9781 agatacttta aataacccta aggtactcca ggtttcctat gacctccttg cccccatgaa
     9841 ccaaccggat caatcttatg gttggatggt tttggataat ctcttcgaat ctctggggct
     9901 cacagccttt ttaaagggta tcaaaacgaa gtctgagtat gacttagtgc aagtgctaaa
     9961 gctattagtt tttcagagaa ttctccgacc agatagtaaa cttgccacct atgcctctca
    10021 agcagactta tttggccatt gggacatcag cttaaatgcc atttatcgct ccttgaacaa
    10081 attgaacacc ttgaaagatg atcttcaaca tcatcttcac aaggtagtga gtcagatgat
    10141 caaacgtgaa gccagtctcg ttttctacga tgtcaccaat tattattttg agacagatat
    10201 tccagataac gagttggttt cagaaaatgg agagatacta caagaagggc ttcgaagacg
    10261 tggtccgagt aaggaacacc gtccaaaacc cattgtgcaa ttaggactct ttagggatac
    10321 caacggtatt ccgattagct ataaactgtt tcgaggtaat caaaccgatc ctgttaccta
    10381 tcttccagcg gttgaggaag tcaaaaaaca atttggaatt gagcggttaa ttgtagtcgc
    10441 cgataaggcg atgaatagta tggctaatgt ttcagaaatg ctcaagcaag aagatggctg
    10501 gctcttctca cagaaacatc gcggacgccg aggagctcca aaagatattc aagaacacat
    10561 ccttgattca tcggattggc aatttaaccc agaacttacc ttcgctaaga aatcttatat
    10621 ccgtgaacgg aagttaggg
//
LOCUS       DARYMD010000065        10617 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYMD010000065 DARYMD010000000
VERSION     DARYMD010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10617
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(56..1390)
                     /gene="trmFO"
                     /locus_tag="TU818_001715"
     CDS             complement(56..1390)
                     /gene="trmFO"
                     /locus_tag="TU818_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL0924507.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELENHPLIEIIREEVIDIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(1772..2485)
                     /locus_tag="TU818_001716"
     CDS             complement(1772..2485)
                     /locus_tag="TU818_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL0924508.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQFAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWMCFF"
     gene            complement(2506..3153)
                     /locus_tag="TU818_001717"
     CDS             complement(2506..3153)
                     /locus_tag="TU818_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0924509.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKACLDQLNHDFSSYIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRTDKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            complement(3268..5400)
                     /gene="topA"
                     /locus_tag="TU818_001718"
     CDS             complement(3268..5400)
                     /gene="topA"
                     /locus_tag="TU818_001718"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL0924510.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPEEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSRLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNSVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            complement(5501..6346)
                     /gene="dprA"
                     /locus_tag="TU818_001719"
     CDS             complement(5501..6346)
                     /gene="dprA"
                     /locus_tag="TU818_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL0924511.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
     gene            complement(6592..7374)
                     /locus_tag="TU818_001720"
     CDS             complement(6592..7374)
                     /locus_tag="TU818_001720"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL0924512.1"
                     /translation="MTAMTIKDIKARLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     EGSVSKPDYLLIDAMTLEVSIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGVTPIHRQSFEPIKSMILR"
     gene            complement(7355..8209)
                     /gene="ylqF"
                     /locus_tag="TU818_001721"
     CDS             complement(7355..8209)
                     /gene="ylqF"
                     /locus_tag="TU818_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL0924513.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADNTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
     gene            complement(8802..9434)
                     /locus_tag="TU818_001722"
                     /pseudo
     CDS             complement(8802..9434)
                     /locus_tag="TU818_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(9436..10203)
                     /locus_tag="TU818_001723"
     CDS             complement(9436..10203)
                     /locus_tag="TU818_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEL0924514.1"
                     /translation="MEQKLNHLAVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     GRQQMIATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQSVMFWFDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQSGYQNYITLLNNIQRERWIMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLGFVASVFLQVE
                     IVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(10485..10617)
                     /locus_tag="TU818_001724"
                     /pseudo
     CDS             complement(10485..10617)
                     /locus_tag="TU818_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
BASE COUNT         3132 a         2398 c         1945 g         3142 t
ORIGIN      
        1 gtcctctcca gatgttagct tgtcaactac ccactacagt tgacatggag cctgattata
       61 ccgttaaata agctgccaga tcagctaagg cacgtttagc gatagcttca tagcgttcct
      121 ttttatctct gatacgaggt ccgtcaagct ctttaataat accaaaattg acattcattg
      181 gttgaaaatg cttgctgtcc gcgtgtgtaa tataataagg caggctgcca attgctgttg
      241 tatttggaaa aacaagtggc tcttcttcct tgaatagccg agcagcatta atgccagcca
      301 caagtccaga agctgctgac tcgacatagc cctccacacc ggtcatctga cctgcaaaga
      361 aaagcctgtg attagcgcgt gattggaagc cttgtgtcag aagctttggt gaatccatat
      421 aggaattacg gtgcatcaca ccgtaacgca caaactcagc atgctcaagg cctggaatca
      481 tttggaaaac ccgcttttgc tctccccatt ttaaatgtgt ctgaaagccc acgatattat
      541 aaaggctgcc tgcagcatta tcctgacgca gctgcacaac agcatagggc gtcttgaaat
      601 caccgtcacg tggtcccttg taatcatctg gatattccaa gccaaccggc ttcattggac
      661 cataaagcat agtcttaatc ccacgctttg ccataacctc aattggcata cagccttcaa
      721 aatacttttc cttttcaaaa gcatttaaag gagcttcctc tgctgttgtc aaagcctcgt
      781 gaaaggccat aaactcttcc ttggtcattg gacagttcag ataagcagct tctcccttat
      841 catatcgcga ttttaaataa accctatcca tgttaatggt tgacttatcg acaattggag
      901 ctgctgcgtc gtaaaaataa aagccagcac caccatttaa ggcatgtatt ttttcagcaa
      961 ggctgtcact ggtcaagggg ccagttgcaa ttactgtaat agcatcgcta ggaatgtcaa
     1021 taacctcctc acgaatgatt tcaatcagag ggtgattttc aagctcagct gtaacagcct
     1081 tggcatagcc ttcgcgatct acagccattg ctcctccggc agggacacga tgggcttcgc
     1141 cagcacgcat aataatcgaa tccagacgac gcagctcttc ctttaaaagc cctactgcgt
     1201 tggttaagct gtcaccacga aaagagttgg agcaaaccaa ttctgcaaaa tgggtggttt
     1261 tgtgttgcgg tgttgccttg acaccacgca tctcatatag cttaacagga ataccacgct
     1321 tagcaatttg ataagctgcc tctgatccag ctagaccagc accaataaca ttaatataag
     1381 attgagacaa tagaccaata cctctttggg gacttatcca tcactgattg ccccgcaact
     1441 ctttctttca agtaattacc ctgcctatta taacagaaat aagagcaaag caaaagaagg
     1501 agctgaacag cctcagtctt ttatataaag gagataagcc cgtacctgca cgctctccac
     1561 aaagctagct gcttcaagca ttttagcttt cgcccaatac cagctatcca catatcttgt
     1621 tcactgcagt agttactgga aggcttttta aggcttattt ttcaaaatct agccaaaaat
     1681 atttcaccgg acctcatcat cttgctggta gcagctaaac aagccttttc cagtaaaaaa
     1741 aaagcaagcg aaagcctgcc cttgttcttg tttagaaaaa acacatccat gctgcgataa
     1801 agacacttaa gacactaaac agcgatccaa tcaaataata ttcagcaaag gctgggcttt
     1861 cagagatttt attgtagcga gcaatagact tagcggtaag caccagtccg attgaagcaa
     1921 attgtcccaa caccatacaa acgcccataa caatacgctc taaattacca atagccgcac
     1981 ccgcccctac aatggtatcc attggtttat cactagctgg ctggaattta ttgaagcaga
     2041 gcttaaagat aatattgaca ggcttggtga tcaaaaccat aaaaagcact aacaataact
     2101 gccgagcatg taaccaatca gggatctcag cctgattaac acgagcgact aaagccagaa
     2161 taatgaaaag atgcaagagc tggtccaaca caaagaccca cgaccgatca agcttaatga
     2221 tacgagccca ttttggctta aaataatcaa taaccgcatg gctactaaaa ataaggatcg
     2281 ctgttagcca aagcttaggt atacacatca ccactagaaa caatggagca gctaccccta
     2341 ataagtgcag ccccagataa gcaaactgct cctccttctt atcagcaata acctgactct
     2401 gaaggtgata atctgataaa aaatgacaaa tcactagcag cactaaaata ggatgctgat
     2461 aaaggtaatc agataagccc tgcataggtg gctcctttcc tctttttatt cttgtaggta
     2521 ggtcaaagct gcatggcgac ttctaagata aacctttaca ctgctgcttt ttaagcgctt
     2581 tgacaaggca cttgattgga ggtccaatgt atcgccaatg agctgttggt caaattgttc
     2641 ttcatagatc cctaagtcta aaagcgcatg aaacacctct aattgactag cacgccagct
     2701 agcttttatc gcctcaccag ctgctaaaag gctattgagc accagatcct tgtgctcctt
     2761 atcagtccgt atagctacct gggtattgcc ataatcattt ttttgatgaa tgtaatgaat
     2821 agcctctctg gcacgccaat aggctggacc gtcagcacca atactaatat cagggttaat
     2881 atcagtcaaa atagtcccct gtccaatacc aaacctaaca gggtagcctg tcatggcttg
     2941 attaattaaa tcaatgagtt gaaaaacagg cgcatcatta gtcaacaagc cttgaaattc
     3001 atcacccaga gtcacagata agttagagac gatataggaa gaaaaatcat ggttgagctg
     3061 atccagacag gcctttaagg actcttgcac caaagaacgc gactgaattt gcttagaatg
     3121 gaccaaatcc ccaataacag cgatatatag catgattttc cctcctttta tgacttccat
     3181 tataacagac aaaaaccaaa aagtccatta taatggaaaa tcatctatat ttccgttata
     3241 atggacctct gctaaaatag ttcaaaccta ctttacaatc tcttctttat agtcacagac
     3301 ttcattgcta cacacaacct gcttacctcc acgaattttt ttctcaacaa ggtaatcgcc
     3361 tgacttcgga caagaccgtc ctaccggcaa atcccacgag gtaaagtcac actcagggta
     3421 gcggtcgcag ccatagaaaa tacggttacg ctttgttttg cgctcaatga cttggccttg
     3481 ctgacaagct ggacaagaaa ctccaatttc ctttgtgatg gcctttgtat gatggcactc
     3541 aggaaagtta ctacaagcat aaaacttgcc aaatctaccc agcttaacaa ccatcgggtg
     3601 gccgcacagc tcacaatcaa aaccagccgg ctcgtccttg atttgaattt tttcgatctc
     3661 cgtttcagcc ttggttaact ccttaacaaa tggcttgtag aattggtcaa tcacattctg
     3721 ccaggcttct ttgccgatct ctatctgatc aagcttatct tccatatcag ctgtaaattt
     3781 gacatcaaca atatcaggga agaattccac aatcaattga ttaacaattt cgcctaattc
     3841 cgtcggctca aagcgtttag cagccagctt aacataataa cgacgctgaa tcacatcgag
     3901 tgttggagca taggttgatg gccttccaac accgttttct tccagtgttt taatcaggct
     3961 tgcttctgaa taacgagctg gcggttgagt aaagtgctgt tcaggtgtta aggtaacctt
     4021 tttaaccact tctccttctg tcatttcagg aagcatcttg cttttatcag aatcattgta
     4081 aacagccata taaccgtcaa atttcatctg actgccattg gcaacaaaaa ggacactatt
     4141 ttgctctagg ttaaccttaa cagtatcaaa cacagcagct gtcatctgac tagcgacaaa
     4201 gcggttccaa atcaaggtat agagctttag ctgatcctta tctaaaaatt tagcaatagc
     4261 ctctggcgta tggttcacat tagatggtcg aatagcctca tgagcgtctt gagcaccagt
     4321 agcattttta actcgattgc catgcttaga gtactgacta ccgaaacgtt caacaataaa
     4381 gcctgcggca tcattttgag caactgggct gatacgagta gagtccgtac gcatgtaagt
     4441 aattaaccct tgtgttccat taggaccaag actaatcccc tcataaagct gctgagcaac
     4501 catcattgtt ttacgagtcc gaaagttaat cttattggct gcgtcctgct gcaatgagga
     4561 ggttgtataa ggtaaaggag catgacgcct gcgttctttt ttctcaacct tactaaccat
     4621 aaaatcatcg ctacttaatc gagacaaaac aagcttaaca tcatcattgg tattgagctt
     4681 catctttttg ccattgaggc cgtaaaagct tgcttggaat ttttttgtcc cttttttaaa
     4741 gagaccatca attgaccaat attcttcagg aacaaaggcc ttaatctcat gctctctgtc
     4801 aatgattagc tttagagcaa ccgattgcac gcgccctgct gaaagcccct ttttaacctt
     4861 tttccagaga attggcgaaa tggaataacc aacaatacga tccagtacac gacgtgcctg
     4921 ctgtgagtca accaaatcca tatcaatttt tcttgggcct tcaaaagctt ctttgacggc
     4981 atcctttgtg atttcattga aaacgacacg attgttatca tcaggatcaa gtcccaaaat
     5041 atgtgataaa tgccatgaaa tggcctctcc ctcacgatcc gggtcacttg ctagataaac
     5101 ctttttagca ttctttgctt ctttttttaa ggcattaatc agcggaccct taccacgaat
     5161 attaatatac tgtggctcat aatgattgtc aaaatcaata gacattgatg attttttcaa
     5221 atcacgaata tgaccaaccg aggcaacgac cttatactga cgtcccaaat atttttcgat
     5281 ggttttagcc ttagcaggtg attcaacaat gactagattt tttttagcag ctgctgattt
     5341 tttctttgta gcagatcttt tcgtctcttg ttttgactta gttgctgttt ttgttaccaa
     5401 ttgacacact tcctataaca gttatggtta aagcttctag cataatatcc cattttttaa
     5461 gaactgtcaa caaaaaattt tctataaata ggaagaaaag ttaagaatag tggtattctg
     5521 aaagaatgtc tctgccatga gtgacacagc tggcaccatc tttgatcagc ttcaaacagc
     5581 ccgccgatgt cccattaaga atattgtcag gtacgacaaa aatatcacgt ccctcttcca
     5641 tagctagctg acaggtaatc aaagagccag agcgctgctt agcctcaaca acaaggacac
     5701 ctcgactaag acctgcgata atacggtttc tttcagggaa atgataagac aaggcggcct
     5761 ctccagcccc atattcactg agcacgagat gacgctgaga taaaaactcc tgtagctggt
     5821 gattttcctt tggatagtag cgatctaggc cagtcccgat aacagctatg gtttgcccac
     5881 ctgctttcaa gcaagcgaga tgagcactgg tatcaatacc tctagcaagc ccgctgacaa
     5941 tgacaaagtg attcttaagc tctttgatga ttttgtaaac agaccgcgtc ccaatttcac
     6001 tggattctct agagccaacg actgccagct taggcttttc taacaggctt aaatcacctt
     6061 gataaaagag taaaacagga ggattataga tttccctcag ggccaatggg tattgcttat
     6121 ctaggataga taagctcgga aactggttga attccttttt taacaaggcg acatttaatt
     6181 gcttgtaggt ctcaataaat aaaactggat ttttgcagca agaaaccact gccatatctc
     6241 taagggatag agacttgtta ttacgctgct ggtagtcaat caggttaaga atatttaaat
     6301 tagttagccc agcctttttt aatttataaa gttcaaaatt attcatcact gtacctctct
     6361 aatgatttat tcgtaaaaaa attaaaaaag ctctgactaa acaaagcttt ttgcaaactc
     6421 ttgaggagct gtacaggatt ccagcaaaaa aatcgaggcc tcctagcctt tgtatgagca
     6481 ttgtagggca gctcatcaca tagcattcca ttgaaaaata ccagaattgt agatccacct
     6541 agtggctatc gtttttgctt tcggcagcta ccttttctca aaatgagatt tttagcgtaa
     6601 gatcattgat tttatcggct caaagctttg ccgatgaatt ggtgtgacac catactggtg
     6661 caatccctgc aggtgctcct tggtcccata gccggcattt ttagcaaagc catagcctgg
     6721 aaaggcctta tcgtaatcaa gcatcaatcg atctctggta accttagcca caatagaggc
     6781 tgcagcgatt gacatagagc tcgcatcgcc ttttataata gcctgttgag gaatagaaac
     6841 ctctagtgtc atggcatcaa tgagcaggta atcaggctta ctcacagagc cctccagctg
     6901 attaatggca gctgtcattg ctaattttgt tgcttcatag atattaaccc ggtcaatggt
     6961 atggttgtca ataattccaa gaccgattcc caacgctttc ttttgaatgg cttggtaaat
     7021 tgcttcatgc ttagctttag gaattttttt agaatcattt agccccttaa tggtgcagcc
     7081 ctttggcagt ataacacagg ctgctacaac tggtccagcc agaggacctc gaccaacctc
     7141 atctatacca gcaatcgctt gaaagccttt ttggtaaagc gcctgttcat acgtcaacat
     7201 cgcctcaagc cgggcttcct cttttaagat agcctctaaa gccctttttc tgctagatac
     7261 agccttttga acgccaagcc gcttatccgc ctttagctct tcaaaaaatg gatcagaaag
     7321 actagaaaca gcttctagac gagctttaat gtctttaata gtcattgctg tcatcatcac
     7381 caacctgatc taaggtgtac tgaccaagtc ttccatcacg aatatccttg atgaataagc
     7441 tgtaaaaacg atcatagtct tccttaaagc caagctgacg tgtcaaggac atgatgattt
     7501 ctggagcgtc agcctctaga tcaatagcct taaaacgctt taataggcga ttaggataat
     7561 acttcttaaa ataattcaat ccaaaaatcg tgacctcgtc cattggcaac agctgatcct
     7621 taatagcccc tgtcagggct aattttaacc caaccaattc gtcttcaaac tttggccata
     7681 agatacccgg agtatccaat atctctagtt ctttattgga ttttagccat tgctgtccct
     7741 tggtcactcc tggcttattg cctactgtgg caattttttt tcccgccaag cgattcatca
     7801 gggttgattt gccagcattt ggaatgccaa taatcatggt tcgtagcgtt tctttttgaa
     7861 tgcctcgttc tcttaagcga cgtagtttat ctgccatcaa ttccttagca gcctcggtga
     7921 cccttttgac cgtagcctgt tccttagcat tgatagctaa tgtcttaatc ccttgcttct
     7981 cataatattg ttgccatttc ttagtatgcg tgttatctgc tagatcagcc ttattaagaa
     8041 gcattagctt gggcttatct ccaacaattt tggtcagcat aggattttga cttgataaag
     8101 gtagcctagc gtctactaaa atcgtcacaa aatcaacatg cttaatattt tcctgtacct
     8161 gtctccttgc cttggacatg tgtccaggaa accattgaat cgtagccatg tgtgtaaaat
     8221 cctttcgtat caagggtttt tagcccctcg tcttttaaaa atcatgcgag tcaccaaaaa
     8281 atcaccaaat attaagcatt atctccagac caagcgatat aattgcaact tgttttggtt
     8341 atttttaatg ccaacaatat caaatgattt ctaatggtat ctggcttata gctattctct
     8401 gctgaataga ttgcctcttc aattttaccc tgtaatctcg ctcagcctgt ctcctgacct
     8461 tgcttttaca tatgaaactg taatattttc cattttacca gttatatgat aaagaaaatc
     8521 aaaatagtcg tagtagaata aattacttta aactattata gcacgatttc ccttatttta
     8581 ctgctaaatt atcctttgta aaagaagata ttaatcgtta taaagaccaa aaaagagaag
     8641 accaaaatga tcccctctag tcttcttttc ggcatatttt accgttattt ggccaacttt
     8701 ccactaatgt gagtaaaatt gtattctaag caagctttac ctattaactt aggagaaaac
     8761 ataatctcta tagctaaaaa taccaaaaaa attatgaatc attatcgcaa actatccata
     8821 gtgatcattt catcagccat ttcccatatt gctggattat gagttgctac gatgattaat
     8881 ctgttagcgt cacgaagaga cagtacaatc tccataatca acttggacgt ggttggatct
     8941 attgaagccg ttggttcatc tgccaaaata aatggcggat tttttaagat gatctttgct
     9001 aaggcaactc gttgtgacta acccccagat agctcaaaaa tgcgtttatc taggttcaga
     9061 taggataaac ctacacgttc taaggcctgt ttctgtctca tcgtttgctc agatttattc
     9121 aatttttgac caatgagacc aagtttgagg ttttcttcaa tcgtttgatt ttcaatcaaa
     9181 ccaaaatttt ggaataggta acccaattca tgacggaaaa aatcactaga tttatagctg
     9241 gctaagtctt tgtctcggta aaaaatagtc ccatgataag gttctaattt ccccatcatg
     9301 ttcatcaagg ttgttttccc gctaccgctt gaaccaatca aagcatagac ttttccaacc
     9361 tcaaatgtca ttgaaagatt agaaaatagc tctcgttctc caaaagattt actcacttgt
     9421 ttaagttcaa tcatgttaac ctcctttcaa aacaagcatg gacatcttgt tttctttctg
     9481 catttgaaca tgtaattgta aaagagatag gccagtgaag agcaacaata ctaagaaagc
     9541 aatcactatc tctacttgaa ggaatacact cgcaacaaat ccgagtaaaa agacacccaa
     9601 ttgagccagg aggtaattcc gatggatttc taaaaatctt agtccagcaa tacgtttgat
     9661 gacaatggca cgtctaaatt cttcaaagta gagcctattc atggtgttaa acaacaagat
     9721 tgaggttgct atcccaagca cagctcccgc aagcattatc caacgttccc tctggatatt
     9781 attcaacaat gtgatgtagt tctggtatcc tgattgcatt tctgagaccc aattttcaat
     9841 gccctgtctc tggataagct cctgggcatc ggacaactga ttaaagagga cataattctg
     9901 taccgcgtca aaccaaaaca tgacggactg aggtccagtt gactggggtg ttacgacaat
     9961 gataatcgga tctttcagaa actgttgata ggaaataggt gtcgtattat acacaaaacg
    10021 gtcttggcct gattccaaat aagccaccgt cgcaatcatt tgctgtcgac catcttgact
    10081 agacatgcga ctagttaagt cgtcttcaaa aacagatttg taatgttctt cctctgaacg
    10141 gagatgctca ggcaagagca agacaaattc ccctactgcg aggtgattca gtttttgttc
    10201 aatagccgta tctacaggga tgttttgacg ctccaagtat tgcggtgtga caataaggac
    10261 attgccattt gggctgtaat cttgccattc tgtagaagtt gtcaagtttt tggaaaagtc
    10321 ttagcctttg ttatcaatac ttgagtagca cctatgtttt tcagattagc ttgctcttgt
    10381 aactgttctg agctattaaa tgctgtcatt tcaacggtga tattttcagt tgattctgcc
    10441 tgcttgttat cttcttttgt tggagattct ggacgtttct caaaataaaa ataattataa
    10501 agctgttgag ccgttactcc tccaccagcc cagccagcaa caggttgacc attcttcaga
    10561 tatagtattg ttggtgttcc tgggattcca actgttttaa ataaaaactc ctgagct
//
LOCUS       DARYMD010000066        10070 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.067, whole genome shotgun sequence.
ACCESSION   DARYMD010000066 DARYMD010000000
VERSION     DARYMD010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10070
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            295..2097
                     /locus_tag="TU818_001725"
     CDS             295..2097
                     /locus_tag="TU818_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL0924515.1"
                     /translation="MEVRGAMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLG
                     ISADYVNHSWVVSNIHNGGEASSSGLAVGDKILEIDHKSSQDNPLLNKLLIVEQATSM
                     TVLHQGIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTF
                     LTSLLLVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLII
                     TYSAATLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRL
                     NIVLLVILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLP
                     VPILYVFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGY
                     QLSNKSIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFE
                     LRELCSNIYPLMIQELGLKNAILDIISKFQKKESVIINDNIQVEQLDFGQPINNFILR
                     SIRELINNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEK
                     LALLGGQLLVDKHPTTIVMLIPRKQVNYDKNSNH"
     gene            2075..2674
                     /locus_tag="TU818_001726"
     CDS             2075..2674
                     /locus_tag="TU818_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0924516.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQREESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            2782..3708
                     /locus_tag="TU818_001727"
     CDS             2782..3708
                     /locus_tag="TU818_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL0924517.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAERYLKEQYEACEDFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFSVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            3701..4072
                     /locus_tag="TU818_001728"
                     /pseudo
     CDS             3701..4072
                     /locus_tag="TU818_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            complement(4106..5457)
                     /locus_tag="TU818_001729"
     CDS             complement(join(4106..5001,5001..5457))
                     /locus_tag="TU818_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL0924518.1"
                     /translation="MKLSYDDKLRIYELRKNGMSCSRIGQQYDIQVSNLKYMVKLMDR
                     YGVEIVRKGKNKYYPPELKQEIIDKVLLEGQSQLSVSLEYALPNAGMLPNWIAQYKKN
                     GYTILEKQRGRPTKMGRKPKKTWEEMTELERLQEELEYLRTENAYLKKLRGASFTGRS
                     QRMRKAETIREMVQEGFRLNLLLEIAKMARSTYYYQVKQLDKSDKDEAINSEIKAIYE
                     EHKGNYGYRRIHLELKNRGFIVNHKKVQRLMKEMRLAARIRRKRRYSSYKGETGKKAD
                     NLIQRQFEAAKPYEKCYTDVTEFALPNNDEKLYLAPVLDGYNSEIIDFTLSRSPDLKQ
                     VQTMLEKAFPADSYNGTILHSDQGWQYQHQSYHHFLESKGIRPSMSRKGNSPDNGMME
                     SFFGILKSEMFYGLETTYQSLNELEQAITDYIFYYNNKRIKAKLKGLSPVQYRTKSFH
                     "
     gene            5518..5742
                     /locus_tag="TU818_001730"
                     /pseudo
     CDS             5518..5742
                     /locus_tag="TU818_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622657.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5761..6405
                     /locus_tag="TU818_001731"
     CDS             5761..6405
                     /locus_tag="TU818_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL0924519.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELW
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYESTQRLYQLIKSLEDKAYQQVLMVGHGAHLTAS
                     IRALLGFEPGMLRAQGGLDNASLTVIETLDFKHFHCLRWNDTSFLQKKTTRLTP"
     gene            complement(6836..7003)
                     /locus_tag="TU818_001732"
                     /pseudo
     CDS             complement(6836..7003)
                     /locus_tag="TU818_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            complement(7241..8446)
                     /locus_tag="TU818_001733"
     CDS             complement(7241..8446)
                     /locus_tag="TU818_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL0924520.1"
                     /translation="MEYIERPKYLNHIEKFVDKPIIKILTGMRRVGKSTILMMIKDEI
                     LKHVPDEQKIYINFESLEFMSINEASFLASYISEKSKNLSGKLYYFFDEIQLVNNWEK
                     VVNGLRVDQDCDIYITGSNSNLISGELATLLAGRYIEFEIQPFTFGEFLKIFSDSNLT
                     KEALFDKFIKLGGMPILKYFKLEEDSSYKYLSDVYNTVLVKDVLNYNKIRDVDIFNRI
                     LSFAIENIGSTFSANSIKKYLKNESRGVSVDTILNYLEYCNRAFILKKVQRFDTVGKK
                     KLKVDEKYYLTDHGFRQARGYSNTKDIERTLENIVYIELVSRGYRVEIGKVKDLEIDF
                     IASKDNERLYYQVSYLMETEETRKREFGVYDFVRDNYPKFVLSMDKVDFSQNGIIHKN
                     VIDFLLESK"
     gene            8526..8924
                     /locus_tag="TU818_001734"
                     /pseudo
     CDS             8526..8924
                     /locus_tag="TU818_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8948..9445)
                     /locus_tag="TU818_001735"
     CDS             complement(8948..9445)
                     /locus_tag="TU818_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HEL0924521.1"
                     /translation="MAKRQVFFSFHYDNDNWRAGQVRNMGKVDSSSTFSDNDWEEVKE
                     KTESKIKEWIDEQLNKRSCLVVLIGEKTANRKWINYEIRKAYELNKGIVGIYIHKLEN
                     SLGEQDDKGNNPFDYLTLEGEKLSKYVKCFDSNYSSSKYVYSDIKDNIEGLIEYGINH
                     KPSTW"
     gene            complement(9446..>10070)
                     /locus_tag="TU818_001736"
     CDS             complement(9446..>10070)
                     /locus_tag="TU818_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="USG protein"
                     /protein_id="HEL0924522.1"
                     /translation="EITEILSTLVDRFRRKTIFISGSAYSYSAYSQKTGENFIHKLSF
                     ELSKNGYHIVNGYGKGVGEFVLNGVADYCLTHKSKINDFLTLMPFPQNSSLGIDLDKL
                     YKENREQMIESCGIAIFLFGNKEAEDIASGVMDEYELSKKHGLVCLPIEYTGGASKEI
                     YDQTTQEISDKNTISAIEQANKQCDGDIDMSVKNIVQAVKILNKEEF"
BASE COUNT         3086 a         1943 c         1661 g         3380 t
ORIGIN      
        1 gcctgtgccc taaccctctc acctagacgc aaaaagaatc aaaacaaccg ttaataggaa
       61 atcatgaaag ccttctatga cagtcattgt tcataggagg ttttttacac caaatagacc
      121 ttctattggc ttttcatttg attcttaatg gatttttact gctaatttct gactcaccat
      181 cgttgcattc gtctcattat ttacaaattt atttggctaa tattgaaaat atgttatgat
      241 taatgtatta ttttggtatt atttttaaaa aatattattt tagaatggta aaaaatggag
      301 gtgagaggag caatgggtaa ccgtcaaatg aagctgaaaa aatacttcct caggttttta
      361 ttgttattat ttgctgcaat ctacatttat ttttcctctt ttgcctatca gcattcctac
      421 cttgggataa gtgctgatta tgttaatcat agctgggttg tcagcaatat ccataatggc
      481 ggggaggcta gctcctcagg actagctgtt ggggataaga ttttagagat agaccataaa
      541 agcagccagg acaatccttt gttaaataag ctgttaattg ttgagcaagc aacctcaatg
      601 actgttttgc accaaggcat acaaagacag attgtatttc aaaaaacaca tgggtctaaa
      661 aagatatttt taatgtttag cctgttatcc attatcttat ttgccttatc ctatggctat
      721 tctagaaggc atgagatcag tcggaccagt cagaggtatt acatctttac ctttttaaca
      781 tcgttattac tggtttcgat tattccatca agcatgggaa atgttgttgc ccgcttgatt
      841 ttagtgattt acatcacttt gtttcccttt tttattgata tgttttggag agcaggtaca
      901 ttgcaacagg aatctgttaa attttcaaaa ttttcaaaac tgatcatcac ctattctgct
      961 gcaaccctct gcttattgct atattctaag tggttttcgg tcccactcgt cattaccatt
     1021 tatttggttc gaggaatttt ctatgttagc tttacctttt tagtggcttt atttttaatc
     1081 accttggtta aagatatcaa aaacaatgct tttccaagac tcaatattgt cctgttggtt
     1141 atcctgtgct tgctgccatt gtttatcggc tatgtgtttc ctttgcctta cgatatccct
     1201 tttatgtaca cgatacccct attgctgctg ccgattttgg cgatcattaa taacctaatc
     1261 attaacaggc tcacgacctt tcgctttcat ttgccagttc caatcctcta tgtgttcatt
     1321 gctatgctag gcactgtgat gatcatttgc ttgtatctca tatcagactt tatgcctaag
     1381 tggttaatga ttagttatag ctttttacta accctgtgct caataccaat cgtaaaagac
     1441 ctgatttttt taaatatcag aacaggctac cagctgagca acaagtctat tttcctagca
     1501 gttgaggctg aaagagagga tatttcgatc tacctgcatg atacgatcat acaagacatt
     1561 atttattaca aaaaaaggct ggaaaatatg gacgccgtct caaaaaaggc tgcttcagat
     1621 attcttgatg atgtaatctt tgaattaaga gagctgtgct caaatattta tcccttgatg
     1681 attcaagagc taggcttaaa gaatgctatt ttagacatta tctctaaatt tcaaaaaaaa
     1741 gaatcggtga ttatcaacga caatatccaa gtggaacagc ttgattttgg gcagcccatt
     1801 aataatttta tcctcagatc aatacgagag ctgattaata atagcattct tcatggtaat
     1861 gctaaggaaa tagatataca catctacaat gctgagcaat acgttgtgat caagattgtt
     1921 gatggcggac attttaagac tgctcgtcag acagaagcgc ctcactttgg cttaactgtt
     1981 atcgctgaaa agttagcatt gctgggtggt caattgcttg ttgacaaaca ccctacgact
     2041 attgtcatgc tcattcctag aaagcaggtg aattatgata aaaatagcaa tcattgacga
     2101 ccacgaattg gtcttacaag gcctatatga tcggttaaaa aaggaaacac attttgaggt
     2161 tgtcggcgct tttaccagct accaagattt gttattttgc ttgaaatata agtctgttga
     2221 cgttttgatt attgatctca tgctaaagga tattcatggc tttgacttaa ttgcacaaat
     2281 ccagcagaaa tgtcagaccg tgccaaaaat gattttaatt tcaggatttt atgagccctt
     2341 gctgcacaaa agagccttgg atctaggcat aaaggccttt cttccaaagg aatgctccta
     2401 cgacgaatta attagcactg tctacaatgt tgcaaaggga aatcaagtga ttccagatga
     2461 cttgctgcag agggaagaaa gtcatctgct aaccgagtca gaaattgaga tattgaaatt
     2521 aatctcagat gaatactcga acgaaaaaat ctccaaaaag ctctatatca gcagaaggac
     2581 tgttgatacc catgtttcaa atatatgtgc taagctcaat gtaacaagcc gagttggagc
     2641 ggtgcgggag gctatcaggc tgaagctgat ctaacaagtc aaccaaaaaa ggcagacaga
     2701 tattcgtaaa ttacggatgt ctgttttttg atagtgtttt atcataagcc ttggttataa
     2761 ataagaaaag gagagaaact aatggttgat gtcgatacat tacttggtga ccacaaaaca
     2821 aggtattttg gtgatggtca caaaagaaca agctacagta taaatcatga ccaaaataac
     2881 caagcttacg gaacaattac ccaatcgggt gtgtggtcaa ataaatctga taaggtgatt
     2941 cagccacacc taagcacctt agatggcatt gttctagcca gtctagcagc tgaaagatat
     3001 ctaaaagagc aatatgaagc atgtgaagat ttttatttat ctcagttttc ggtcaaatca
     3061 ggcaggaagc ctattgaaga tttaaacagg gttccaattg ttgtccaaaa aagctctttc
     3121 aatggggata aggcaagctt ttcggtgtca gtgctggata tgactgttaa tctagtattt
     3181 aaacgcattg acacctatac agcaaaagac aacaaaccag ctgcagaggc aaaggattac
     3241 ttgtcaaatc atctaaagga cattcaccat catatctacg atgttaactt tttagacgca
     3301 ttagatatag cagataagtg ctctattttt tgtaaggcta ataaggcaat ccgccacgtc
     3361 agcaattata agggcatatc ctctcagcta tcaagcagct attccttatt agagctcttg
     3421 attattttct cacagatggc tgaaatgttg gcatattatg ctgatgatat tgatagaaga
     3481 tacagtgaaa ccttgtggat gaaaaatgta tcagccgagc tcgttgaacc gatacctgat
     3541 ggtgagctgg cccttttagg taaaattacc aaaaacaaat tacttgatat gaagggcaag
     3601 gactggaagc tgtttgaaat gtcaggtact gacacacaaa atcgagtgag aatttcaagt
     3661 aaaatagccc atcaattacc tagttcggag atgcttaaca atgcttaata aagaaattag
     3721 acttgtcata tcaggcacct attctactgg taagacaaca acagcaacgg ctctgtctat
     3781 tgcgacaggc atacctttga ttaatgcact ttcagccaga gagatcctga ccgacctgta
     3841 tccaggcaga cgctttcagg acatgaatgc cactgagcta atggctctag gattaaaaag
     3901 atttgaggag cgggtgcgcg aggaagccat tttatacctc cagcatacca actttatctc
     3961 agatggctcc gtgctaaatg aatggatcta tggaacagta cgaatgaagg taggcttaaa
     4021 tccgggctct ggcttcattc atcgagctgc aaaggccatc cttggacttc ctgtgtactg
     4081 acccccaaaa gttggacacg acatattagt gaaaggattt agttctgtat tgcacagggc
     4141 taagtccttt tagctttgct ttaatgcgtt tgttgttgta gtaaaaaatg taatctgtaa
     4201 tagcttgttc aagctcatta agggattgat aagttgtctc aaggccgtaa aacatctcag
     4261 atttgagaat accaaagaag gattccatca tcccattatc ggggctgtta cccttgcgag
     4321 acattgatgg acgaatgccc tttgattcta aaaaatgatg ataggactga tgttgatatt
     4381 gccacccttg atcgctgtgg agaatcgttc cattgtacga atccgctgga aaagccttct
     4441 caagcatggt ttgaacctgt tttaagtctg gagacctaga tagtgtgaaa tcaataatct
     4501 cactgttgta gccatcaaga acaggcgcta aataaagttt ttcatcgttg tttggtaaag
     4561 caaactctgt cacatcggta taacattttt catatggctt agcagcttca aactggcgtt
     4621 gaatcagatt atcagccttc ttaccagtct cgcctttgta agaggaatac ctgcgtttac
     4681 gacgaattcg agcagctaat ctcatctctt tcatcaagcg ttgcactttc ttgtgattga
     4741 cgataaaccc acgattcttg agttctaaat gaatgcgacg gtaaccatag tttcccttat
     4801 gctcctcata aatcgctttg atttcagagt tgattgcttc atctttatct gacttatcca
     4861 attgcttgac ttgataataa taggttgaac gagccatctt agcgatctca agtaggaggt
     4921 ttaatcggaa tccttcttgg accatctctc taattgtttc tgcctttctc attctctggc
     4981 ttcgtcctgt aaacgaagct ccctcaactt ttttagataa gcattctccg ttctaaggta
     5041 ttctagctct tcctgaaggc gctctagctc tgtcatttct tcccaagttt tctttggttt
     5101 acggcccatc ttcgttggtc tccctctttg tttctcaaga atagtatacc cgtttttctt
     5161 gtattgcgct atccaattgg gaagcatacc agcatttggg agagcatact caagagagac
     5221 agacagttga gactgacctt caagaagaac tttatcaatt atttcttgtt ttaattctgg
     5281 aggataatac ttatttttac cctttctaac aatctcaact ccatatctgt ccataagctt
     5341 taccatgtat ttgagattag aaacctgaat atcatactgt tgaccaatgc gggaacaaga
     5401 catcccattt tttcttagtt catatattct taatttatca tcgtaactta atttcatata
     5461 aaaagcaccc cattggtaga ttttctgtct aacttttggg gtgcgggtca cgctttgggt
     5521 ctttttcctt ttggaaaagc catcgaaatt ggccaaggag caggcagcct gctgctcaat
     5581 atcatctgga ttgtctgctg tggctggagc ttagcgatca tgcatttgac ttctgccctt
     5641 ctcttgtgcc tcacgattgt tggcattcca tttgcccggc aatctctaaa attggccaag
     5701 attagcctct ttccttttgg agccatcatt tatgacattt aattaggaag caaaagactt
     5761 atgaaattgt attttgtcag acatggtaaa accttgtgga acctagaggg ccgttttcag
     5821 ggagctaacg gagattcgcc cttgcttgaa agctctaagg acgatttgcg ccagctagca
     5881 agagagctgt gggacatttc ttttgatgcg atctactcca gcgacctaaa aagagctgtt
     5941 gatactgctc gcattattgt ggacgaagct aactgcaaga ctgatattag ttataccaag
     6001 cagctgagag aatggaacct aggcaccctg gaaggaacca aaatagcaac tgtatccgcc
     6061 atctacccca gtcagatgtc agccttttat cacaatttag ccaaattcaa gcccagtcaa
     6121 tttaaggctg aatcccttta tgaaagcaca caaaggcttt atcagctcat taaaagtttg
     6181 gaagataagg cctatcagca ggttttaatg gtaggacatg gcgcccattt gacagcttct
     6241 attcgtgctc ttttaggctt tgagccaggt atgcttcggg cacagggagg actggataat
     6301 gccagcctaa ccgttataga aaccttggat ttcaaacact ttcattgtct aaggtggaat
     6361 gatacatcat ttttacaaaa aaagactact agattaacac cctagtagct cttaagcaca
     6421 aagctccaag acagctaaac tgtactccat tggttagaga acacatctca ttttttgagg
     6481 gacgctttat tagctgtagg aagttatgaa aagctaaata cacgagagga ctaaattgga
     6541 caagctcaaa agtttgacaa tgtatttcaa aaaaggattg aattctgtat cgaacaggac
     6601 tcagtccttt ttatcattta tcaagccgac caaggctttc aaccacgaca aacgcgcaaa
     6661 acagttattt cctgatgata gtagagacta cagcagatat tttcaatgat tttcttgtag
     6721 taacatctat acaaaacaat acagctcatt gaaatatagg aacattaaaa ttcagaaaga
     6781 tttcttttct tgctaaaaat ctttcatcca tttcaaactg gttttcattt gtcctctcct
     6841 ttttcagttc tgctttttct ccataagctg cacagttgat gtactccttg cctttaccgt
     6901 acttctttac aaatgtaaaa tttacaactt atacttcttc tccttctctt tcaaaacttg
     6961 agtaaattga ttctgctact aaatttgcgt taatattaat cattttttat ccataatttt
     7021 tctccttttt taatttaaaa ttcccattaa aaaagcgact ggactttttc caatcgctga
     7081 tacttctact attttatttt tatttcggta gaacttctaa tccttatcat ctatatcctc
     7141 ctttttaaac acaaaaaaga cggtagattt tttctttttc cattgtctct tataacttat
     7201 atttaatttt tgaatagtat gcaaacattt aaggaaacaa ctacttgctt tccaataaaa
     7261 agtcaatcac atttttgtga ataattccat tttgactaaa atccacttta tccatggata
     7321 agacaaattt aggataatta tctctaacaa aatcatacac accaaactct cgttttcttg
     7381 tttcttctgt ttccatcaaa taagaaacct gataatataa cctttcatta tccttacttg
     7441 caataaaatc aatttccaag tcttttactt tgccgatttc aactctatat cctcttgaaa
     7501 caagttcaat ataaacgata ttttccaatg ttctttcaat atcctttgta ttggagtatc
     7561 ctcttgcctg cctaaatcca tgatctgtaa gataatattt ttcatcaacc tttaacttct
     7621 tttttcctac agtatcaaat ctttgtactt tttttagtat gaaagctcta ttacaatact
     7681 ctaaataatt taaaattgta tcaacagata ctcctctgct ctcatttttc aaatactttt
     7741 ttatactgtt ggcggaaaaa gtagatccga tattttcaat agcaaaagat aatatcctgt
     7801 taaatatatc tacgtctcgt atcttattat aattaagcac atctttaacc aagacagtat
     7861 tatatacatc gcttaaatat ttataactgc tatcttcttc taacttaaaa tattttaaaa
     7921 tcggcattcc acctaatttt ataaatttat caaaaagtgc ttctttagtt agatttgaat
     7981 cactaaaaat ctttaaaaat tccccaaaag taaatggctg tatttcaaat tctatatatc
     8041 ttcctgcaag aagtgtggca agttcaccgg aaatcaaatt tgaatttgaa ccggtaatgt
     8101 atatatcaca atcttgatct actcttaacc cattaactac tttttcccag ttatttacca
     8161 actgtatttc atcaaagaaa taatataatt taccacttag attttttgac ttttcactta
     8221 tataacttgc caaaaagctc gcttcattta tactcataaa ctccaaagat tcaaaattga
     8281 tatatatctt ttgctcatcc ggcacatgtt tcaaaatttc atctttaatc atcatcagaa
     8341 tggtagattt tccaactctt cgcatcccag ttaagatttt aataataggt ttatcaacaa
     8401 atttttctat atggtttaaa tacttgggtc gttcaatata ttccatatca ttcacctctc
     8461 tttagctttg attatattat acacgataaa aatatatttt ccaatattgt tttcgaatat
     8521 aatcgaaata tatcataaaa gcagccgatg aaaggcaaaa tttacaggat aagatcaagg
     8581 ctattgataa ggaaatgcag gagctttctg ccactatgga gcaagttcac actgttaaaa
     8641 aatacaggca atactacaaa gaatataagg caagtccatc tgacaaggca ttttttgaag
     8701 agtacaaagc tcagattacc ttatatgaaa atgccctttc agagcttaaa aaatcatatt
     8761 ccaagttgcc aaattctaag ggtattttag atagacttga taaattgcaa gaaaaaaaga
     8821 atacccttat gcaagagtat tcttcctcaa aatctattat ggacgaactt tacaagatac
     8881 gaaaaaatta tggaatttac atgggtaagg agatggagag ataatttttt ctctccatca
     8941 tcatttatta ccaagttgat ggtttatggt ttattccata ctcaattaaa ccttcaatat
     9001 tatctttaat atcgctataa acatatttac ttgatgaata gttggagtca aaacatttaa
     9061 catactttga aagtttttca ccttctaatg ttaaataatc aaaaggatta ttacccttat
     9121 catcttgctc tcccagtgaa ttctccaact tgtgaatata aattcccaca atacctttat
     9181 ttaactcata tgcttttctt atttcataat ttatccattt tctgttcgct gttttttctc
     9241 caatcaaaac aaccaaacat gaacgcttat ttaactgttc atcaatccat tctttaattt
     9301 tactttcagt tttttctttt acttcctccc agtcattatc agaaaaggta gaactactgt
     9361 ctactttccc catattgcga acctgtcctg ccctccaatt atcattgtcg taatgaaagc
     9421 taaaaaatac ctgtcttttt gccatttaaa attcctcctt atttaatatt ttaactgctt
     9481 gaactatgtt tttaacagac atatcaatat cgccatcgca ttgtttattt gcctgttcaa
     9541 ttgcacttat tgtattttta tctgaaattt cttgagttgt ttgatcatat atttctttag
     9601 atgcaccgcc agtatattca ataggcaaac atactaatcc atgctttttt gataactcat
     9661 attcgtccat aactccgctt gcaatatctt ctgcctcctt attaccaaaa agaaatatag
     9721 ctataccaca actttcaatc atctgctctc tattttcttt atatagctta tctaaatcaa
     9781 tacctaatga actattttga ggaaaaggca taagtgttaa aaaatcattt attttggact
     9841 tgtgagtcaa acaataatct gcaactccat ttaatacaaa ttcaccgact cctttaccat
     9901 atccattcac aatatgataa ccattttttg atagttcaaa agatagttta tgaataaaat
     9961 tttcgccagt tttctgagaa taagccgaat aggagtacgc actaccagat ataaatattg
    10021 ttttccttct aaatctatcg acaagagtgc tcaatatttc ggtgatttca
//
LOCUS       DARYMD010000067         9980 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYMD010000067 DARYMD010000000
VERSION     DARYMD010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9980
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(484..2061)
                     /gene="cls"
                     /locus_tag="TU818_001737"
     CDS             complement(484..2061)
                     /gene="cls"
                     /locus_tag="TU818_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL0924523.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMLELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(2277..5617)
                     /locus_tag="TU818_001738"
                     /pseudo
     CDS             complement(2277..5617)
                     /locus_tag="TU818_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
     gene            complement(5931..7601)
                     /locus_tag="TU818_001739"
     CDS             complement(5931..7601)
                     /locus_tag="TU818_001739"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL0924524.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDADDLELYGNYKAKLSFEK
                     IKSVEDNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGVPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENTAAVRSGFANLKRHVENIRKFNIPIVVAINEFVTDTKAEIQVL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVKAITEESAAYKRLYADKDSLEEKLKA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
     gene            7799..8491
                     /locus_tag="TU818_001740"
     CDS             7799..8491
                     /locus_tag="TU818_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL0924525.1"
                     /translation="MAMKLLITSGGTTEAIDAVRGITNHSTGQLGKIVAETFLAKGFD
                     VTLVTTKTSVKPAQQPHLTIREVTNVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMT
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKVISYIKEWNPNIRLVGFK
                     LLVNAPAEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVNDKTVCSASTKEEL
                     AQLIYERIIAND"
     gene            8484..9029
                     /gene="coaC"
                     /locus_tag="TU818_001741"
     CDS             8484..9029
                     /gene="coaC"
                     /locus_tag="TU818_001741"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL0924526.1"
                     /translation="MTKRITLAVSGSISAYKAADLTSQLTKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPEATPKLIAPAMNTNMYLNPITQGNIKRLADLGFREIPPKTALLACGDR
                     GPGALADIDDMVTAISQQLAR"
     gene            9086..9658
                     /locus_tag="TU818_001742"
     CDS             9086..9658
                     /locus_tag="TU818_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0924527.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGIVSVITNTLVLLPTSHLFSPFVTNGNLASLMIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFIFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
BASE COUNT         2914 a         2223 c         1868 g         2975 t
ORIGIN      
        1 tgacagagtg tttcctgaat ttttatattt ttcctctata aacttttctt gaaaaatttc
       61 ttttctgcaa ctatcgctat ggctttccta tttttcagaa caagttttcg catttcagaa
      121 atatcttgga aattttttct tcatgcgttt gtcgtagcta gaagcttatg gtatgacagt
      181 caatagataa gtttttcaca tcagtgctat tgttccatga taacataccc ccttagaaaa
      241 ggcagttatg ctatggatac gatgagactc acacctaaca cagtgagatg actaaacatc
      301 acaacaaaaa aagctgagag aaactctcag ctctcagggg cattcgtatc acgaatgtga
      361 taaaaaggtt cacacaaatt atcaaagtcg gctcctgcct taatgacctc cccagcacaa
      421 ctgtgattta aaaatcacaa tcgactcatc gcataggcct attatagcaa acatatcatc
      481 tctttacaag aggggggcta ttgttttaac caataaacca acgagctttt gataccaagg
      541 cctttgcctt agctgacttt ctgtgactag cttagagctt gcctgggttt ctttgaaatc
      601 ctgaacaatg tctgcaataa cagaggaacg gtaaaggtag gtggcgcatt caaaatgatg
      661 atagaggctg cgataatcca gattaatggt tccaacgact gccttagaat catctgaaat
      721 aaagacctta gaatgcacaa atcccggact atattcgtag attttaactc ctgaggtgat
      781 caagccttta tagtaggttt tagcaagggc ataaggaaca gccttgtcag gcttacctgg
      841 cataataatc cgaatatcca cccctcgctc tgctgcaaat ctgagggcat gctctgtttc
      901 gctatccaaa atcaggtatg gagtcatgat ataaacatat tccttagcgt gattcaagat
      961 atcaatatag acatttctgc caattttgtc agtatcaagt ggtgagtctg cataaggaat
     1021 gacatagcca tctgaggcga cctcctctgt atgctgggac agataaggct ccacgatcag
     1081 ccttttttcg gtaattgacc acatttgtaa aaacatgatc aaaaagctat caacagcctc
     1141 accctttagc ataagacctg cgtccttcca atgcccaaag cgtttgacct cattaatgta
     1201 ctcatcagct aggttaatac cgcctgtaaa ggccacctct ccatcaatca ccacaatttt
     1261 acgatgatcc cgataattgt agtaggttga aataaaaggc gagatcggca aaaaagactt
     1321 tgctttgata ccaatgcgtt caagtctggc agcataatcc gctgataagg tcgacagctc
     1381 tagcatgcca tcaaaaagaa cgcgaacctc tactccctct tgcaccttct tttctaaaat
     1441 tcctaaaatt tctccccaca tctgcccctc tgcaatgata aaaaattcta gaaaaatata
     1501 ggacttagcc aataaaagct gagtttttaa accttcaaaa aaggcttctc cgatgggaaa
     1561 gtaggtggct tgagtcttgc gataaatggg aaaattccca cgactacgct ctaaatactg
     1621 aacgaggtga taggtcgttg aggtatgccc cttcaacgcc tgtaaaatag cgtcatcatc
     1681 tctcaagtaa ggagaggaca aatcaactaa atggttaatt cgctgcttta ggtcacgata
     1741 accccagtct aatttagtgt aaataagaaa taaagagcct agtaaagggg ctatcataat
     1801 gagaatcagc caggtcaccc ttgaaatagc gtccatatcg ctattcacca agtacaagac
     1861 aattgaaatc gaaaaaatac gctcaataat agcaattaaa acacgatact gctccatcca
     1921 agcataggat tggcataaaa agaagatttg cagaacgatc aaagcagcaa taatggttgt
     1981 tctgctgaaa atccccctca gcaagccttt tttcccttta tggagcaggt atcttacttt
     2041 tttattcttt ttgatagtca accctccagc tttatttttt cttattatat cataaaactg
     2101 gaggtcatga tttaagtcgc tgctaaaagt ttcagcaatt ggtgcaagca ttaaaaaaag
     2161 acctcaatac ttcttttaca acttgtaatc ctcacaaaac ctactgcttt aacaaccaaa
     2221 aaaagattga aggagacatg cttccccttc aatccaagtc tcatcaggtg atgagattaa
     2281 ttatctgatt tctttttaaa taagcctaga gataggctag ctagtagcat acctaagcct
     2341 gctaataacg atgagcccta tgcctgctct gaggttttag gaagctcatg gctatgtgct
     2401 ggagccattg gtttgctgct atctggtgtc atggctagtg actgctgatc tgctttgcta
     2461 ttatcagaag actgatcttg atcagtagaa ccattgccct taggctgctg ctctggcatt
     2521 ggtgtctcag gctgtttgtc gtctttaatc tctggttcct tttggtttaa aaggtctgta
     2581 agagcaatcg cgttaaagtt gccaaattca tcttcaacaa ttaatgtcaa ggcagcaata
     2641 ttaacctcta cctcctcacc tgacagctct gacatcaccg ttgctggaat gctaaatgag
     2701 ccgtcctcag ccattgggaa gtagttcacc acaatatctg cttcctctcc ttctccaatc
     2761 tcgacaatat ggccaacctg aatacggtag gctgagaatt tagcagtgtc gatcttaagt
     2821 gttctggtag attcgtcata ggaagctgat tttggtagct ctggtaggct tgttttcact
     2881 tgaaccttaa agtcttgctt ttgagcctca gcaccatctg ctacaggagt ataccaaacg
     2941 cgataggtat agctaccatc tgctacaggc tgatcattgg cgtcttttcc actccatttt
     3001 gtatgctcaa agcgatacgg taacacaaca ccctcttgat agtatttctg ggctgaagaa
     3061 acaccacttt cccaaacgat ttgtccattg tgatcaagaa cctgagcttt aatatcctta
     3121 acgcttctta ggaatacccc ttggaagaga ataaaatcct tattaccatc atcatttgga
     3181 gaaatcaaga aggttctatc tgcctctttt gctattaaat ccttttgatc agctgactcc
     3241 tgtgttccta aaataatata tctttctgcc tcagggccta actcattgac cgttccattt
     3301 tttgtatcct gtgccaagaa atatgggctg acctgaccaa tcaaagcagt tagcttgctg
     3361 aatttctctg gtaatatgta tttacctgtt tcaggatctt gctcaagctt ttgataaaag
     3421 gcaccctgct caagcgtctc ataaatagga gtatctaagg ctggcaagtt agcaaaatca
     3481 cccctaaagc cactaaatgg aatactcatc aattcttcct tagtgtctaa attgtctgtg
     3541 aaacggacaa agccttcaag gaagtagcca tttggcattg cttttaacaa ttcagcagcg
     3601 taagccttag cgtcaacaga aacttgaata tgctgctggt cctcggtgat attaatttcc
     3661 tgccactctg aatcctttaa tgcttttggc tgcaaggtga agtgaccatc tttagtttga
     3721 tcagtgatta ggttgacttg gaaataaagc tttttaggcc cttgattttt cgatagggca
     3781 ttaacattta gattaatgac aaattcatct gcaatgttcc ccagattgat tttagggttt
     3841 tgcttctgat cagtaaggta atagctggct gctagtgcct tttgaccatc tacctcacca
     3901 gcaccctgct ggcgtggaga aatataagcc ttgttttctg tgctataaag tgttcttgct
     3961 gagctcatca acacagctct aacaagctga gaaagctcct tatcagaaag ctctgggaat
     4021 ttctctttgt aagctttatg tagcatggcc acaagccctg acaccatagg tgttgacatg
     4081 cttgtaccag tcttgtaatc atattggtta ccatgaactg cagagtagac attgacacca
     4141 ggtgctgaaa tatctggctt gatacgacct tctgctgtca caccccagct ggattggctg
     4201 ataacgcggc caccagcatt gctaagcatt ttctcatagg ccttattaaa tctaaagctt
     4261 tgaccttcct taagagcttg agcgtccttg tagctcataa agccaacagg aatgtgagct
     4321 tcctttggaa tagaggcctt ttcaatcgta aagcttcctt caagcgcatt gttattgtag
     4381 ataatcacac cgctagcacc agctttaaca gcattttcaa tcttttgata aaagctaagt
     4441 gagccgccac gttcaatcaa agcaaccttg cctttaatat caagaccagt aaagtgagag
     4501 gcttcaccga atttggcatc agccacaaag taatcctgat cagcatcaaa tgagtcgccc
     4561 tctgacataa agatcgctag tttttgacta ccgtctgcgg tcttagcatt aacagactgg
     4621 ctaatagcgt aaacaggatt ggaagccgca acactgataa cctcttcaaa aatagctgga
     4681 ctattaaggg taccaaaatc aggatttgct gctagaggct ctcgagttcc cataccaact
     4741 gcactctcat taccagctcc agcaaccaac aaaacaccct tttcttgagc ataggctata
     4801 gcctttttaa cgtcctcatg aaccgttgat aaggaatccg ctgtttttcc aaagctcatg
     4861 ctaatcactg tagctcctag attaaccgcg tctgtgatcg ccttagcata ggattttgca
     4921 aattgatccc tttctggggc accagtcacc ttcatcagca taagagaagc atttggtgca
     4981 atcccctcaa cacgaaggcc atttcctgct ggtgttttcc cattacctgc tgctatagcg
     5041 gcagtatggt taccatgacc attatcagcg gtcaagccgc caatatcatc tgattgcttg
     5101 gtgtaatcgt aggcaaaaat aattttttcg ttgtaccact taccgtatgt gattttctga
     5161 tcctgctttt tagcaagaaa tgcctcttta gcaggaatag tatcgctatt ttttaagtcc
     5221 gaatcaagct taaaggcgtc atgctcagga tcaaaggaaa catcaataac agcaataacc
     5281 gctccgcttc ccttttgtgt ttactcttgt agggctttag cgttgaccga gtcattcagt
     5341 gataaattgg tcggtgctgt actctctggg ccttctgcaa aggctgatat ttctttttct
     5401 gttttagctt ctgtttctga agtcgcctgg ctgcttgaga attgtcatcc gtagcagtag
     5461 cttcaacagc tgcaactgga ttcacttgtg atacagaagc gtctaagtcc tgctgctcct
     5521 cagcaaatac agtctgacta tgaagcaata aaatacttgt tgtagccaat gttaactggc
     5581 ataataaact tttctttgag tgatattttt tagtcactaa taaaacctcc atttgtacct
     5641 gactataata atataacaat atctctttat taacaataga tttgtgaaaa attaatttta
     5701 tcatttaata ttaaaagtca gattattaaa aaatatccct accaaagcag aattaaagca
     5761 ttaatgattg tcaatatgac acctatactg gtaaaaaaag attgtgaata acgattaaaa
     5821 tagtaaaata tgagctattg ttatcagctt atccttagac attaaaaaag attgaagaaa
     5881 ccccctttct gaagctttct tcaatcctga ttctggctat aacaaataaa tcaaaacaat
     5941 cctactgctg taccgtcttc ggtgacgtcc atcttcatag ctgcaggaat ctttggcaag
     6001 cctggcattg tcatcacatc tccagttaag gcgacgataa agccggcacc ggtcttaggc
     6061 actaattcac gaatggtaat gtcaaactga tctggcgcgc ctaggagcga tggatcgtct
     6121 gaaaagctat actgggtttt ggccatgcaa acaggcaatt gatcccaacc aaactgggca
     6181 aattgcttga gctgattttt agctttaggt ccgaattgca cagccctacc accataaatt
     6241 tcagtcacaa ttgccttaag tttctcctct aagctatcct tgtctgcata tagacgctta
     6301 taggctgcgc tttcctctgt aatagccttg acaacagcgt tggcaagagc aataccgcca
     6361 tcagccccct tggcccacac gcttgccaat tcaaccggaa cagctatttc tgcacacaat
     6421 tcttttaaga cttgaatttc tgctttagta tctgtcacaa attcgttgat agctacaaca
     6481 atcggaatat tgaattttcg aatattctca acatgacgct ttaaattagc aaagccagac
     6541 cggaccgcag ctgtattttc aaaggttaaa tccgccttag caacaccgcc atgcatcttc
     6601 aaggcacgaa gtgttgcgac aataacaact gcatcaggag ccttaggtag attcggtgtt
     6661 ttgatgttaa ggaatttttc tgctccaaga tccgctccaa agcctgcctc tgtaacagta
     6721 taatctgcca accgcaaagc tgttgatgtc gccagaacag aattacagcc atgagcaata
     6781 ttggcaaagg gtccaccatg cacaaaggct ggtgtaccat agattgtttg aacaaggtta
     6841 ggcttgatgg cgtccttcaa aatcaaggct aatgcccctt ctacctttaa atcacgcaca
     6901 tatacaggtg atttatcgta acgataggca atcacaatat tagctaaacg agccttcaag
     6961 tccttaagat cagtcgccaa gcaaaggata gccatcactt cagaggctac tgtaatatca
     7021 aaaccgtctt ctcttgggac accattgaca ggactcccca agccaacaat gacctgccta
     7081 agagaacggt cattcaaatc aaggacacgc ttccagatga tacgacgcgg gtcaatacca
     7141 agctcattgc cctgctgaag gtgattatca ataagggctg ataaagcatt atgagctgtg
     7201 gtaatagcat gcatgtcccc ggtaaaatga aggttaatat cttccatcgg aagaacctga
     7261 gcgtagccgc cacctgcagc accacctttg atccccataa ccggtcctaa agagggctca
     7321 cgcaaggcca gcatggtttt tttaccgatt ttagtcaagg catctgccaa accaatagac
     7381 atggttgatt tgccttcacc tgctggcgtt ggattaatag cagtcactaa aatgagctta
     7441 ccaggcttat tgtcctctac tgatttgatt ttttcaaagg ataatttggc tttgtagtta
     7501 ccgtaaagct ccaaatcatc agcatcaatc cccacctttt taacgatttc tgtaatcggc
     7561 tttaagggga cactttgagc aatttcgata tctgatttca tgaaaactcc ttgactctta
     7621 cttgatagtg ttattatatc acacttcatc tcaaacgtac attgatttgt tctatataca
     7681 aaaatgttcg tttttataat ggttctgaaa ggaaaaaagc ttagtagcgt cagcattgtc
     7741 agtaaaaata attttaatta gtgattttat ttactattct tgctttttct gataaaatat
     7801 ggctatgaaa ttattaatca catcaggcgg aacgaccgaa gcaatagacg ccgttagagg
     7861 gattaccaat cattccactg gccagctagg aaagatagta gctgagacct ttctagcaaa
     7921 gggatttgac gttactctag tgacaacaaa aacttcagta aaaccagcac agcagcctca
     7981 tttgaccatt cgtgaggtga ccaatgttga tcagctgatg gctatcttaa aagaggaggt
     8041 tcctaagcac gaccttctca ttcacagcat ggctgtttca gattatagcc cagtgtacat
     8101 gacagacttt gatacagttg cagctgctga tcatttacag acctttttaa cagcaagcaa
     8161 taaggaagcc aaaatctcat cggcagctga ttatcaggtg ctctttctta aaaaaacacc
     8221 taaagtcata tcctatatta aggaatggaa tcctaatata aggctagtcg gctttaagct
     8281 attggtcaat gctccagctg aggagctaat ttcagtggca cgagatagcc tgcataaaaa
     8341 caaagcagac tatatagtag ccaatgacct agcagatatt aaggccaatc agcacaaggc
     8401 ttttcttgtc aatgacaaaa cagtctgctc tgccagcacc aaagaggagc ttgcacaatt
     8461 aatctatgaa aggataatag ccaatgacta agcgaataac acttgcggtc tcaggtagta
     8521 tttctgccta taaggcagct gatctcacca gccaattaac caaaaaaggc tatgaggtta
     8581 ctgtgttgat gacgcaagca gctactgcct ttatcactcc gttgacccta caggtcttat
     8641 cgaaaaatcc tgtccatcta gatgtcatgg cagagcacga tgtcaaaatt gtcaatcata
     8701 ttgagctagc taaagcaaca gatctatttg tccttgctcc tgcaagtgcc aataccattg
     8761 ctcatttagc ctacggcttt gctgataata tggttaccag tgtcgcccta gccctgcctg
     8821 aggcaacacc caaactcatc gctcctgcta tgaatactaa catgtacctt aacccaatta
     8881 ctcagggaaa catcaaacgc ttagctgatc ttggctttcg agaaatacca cctaagacag
     8941 cactccttgc ctgcggcgac agaggacctg gggccttagc agatattgat gatatggtta
     9001 cagcaattag tcagcagcta gcaagatagc tggtcaccga ttagcaattg ctgtattata
     9061 atataaaaat ttaatggaga atgcaatgaa tcataacaaa tcttctgaaa tctctcgtat
     9121 tgccatcttt tttgcagtca tgctggttat tcacttcatt agtagctggt ttttttatat
     9181 ctggcctgtc ccaattaaac caacactcgt ccatattcca gttattgttg cttctatcat
     9241 gtatggtccg cgcactggag ctatcttagg aggcttgatg gggattgtca gtgtgatcac
     9301 aaataccttg gttttacttc caacaagcca tcttttctca ccatttgtca caaatggtaa
     9361 tctggcttcc ttgatgatcg ctatgctgcc tcgtatcctg attgggatca ctccttatta
     9421 ctgttataag cttatcaaaa acgagcttgg gcttgtccta gctggtcttg ttggctcgct
     9481 gacaaacacc atttttgttc tctcaggaat atttatcttt ttcccaacag cctctggtga
     9541 caatgtcaaa acgtttctaa ctaccattgt atctggcaat gctattactg aaatgattgt
     9601 ttcagctatc gttaccatta ctcttatccc agctttatcc aagctcaaaa aatcataata
     9661 ttgctcaagc tatgaagcat gctgtctgat aaggatagca tgctttaatg atatgtgaca
     9721 agcaaggaaa ttgatcctta tgtgaaaaaa tgattggaag ctattacaga aaataagtga
     9781 tttttccttt tcaacatgat ataatcccga ctttatcact taaaaacaag taaagaccag
     9841 ctaacccctt gtgtcccaag ggattttgct ggtctttaaa tttattttag tgttgtatat
     9901 ggatttttag cgtaatgttt gagctcttca aacttaacga ttcccttcgc ccattcaatt
     9961 cctagcagtc tgtttaactc
//
LOCUS       DARYMD010000068         9817 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYMD010000068 DARYMD010000000
VERSION     DARYMD010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9817
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            205..942
                     /locus_tag="TU818_001743"
     CDS             205..942
                     /locus_tag="TU818_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL0924528.1"
                     /translation="MIITSKANHLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKLCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAAKFDGVFLSEKSADVYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQVMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            981..1481
                     /locus_tag="TU818_001744"
     CDS             981..1481
                     /locus_tag="TU818_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL0924529.1"
                     /translation="MHYTEDTEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            1500..2189
                     /locus_tag="TU818_001745"
     CDS             1500..2189
                     /locus_tag="TU818_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL0924530.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIVLDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            2583..2825
                     /locus_tag="TU818_001746"
     CDS             2583..2825
                     /locus_tag="TU818_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL0924531.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            3005..3799
                     /gene="racE"
                     /locus_tag="TU818_001747"
     CDS             3005..3799
                     /gene="racE"
                     /locus_tag="TU818_001747"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL0924532.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            3796..4785
                     /locus_tag="TU818_001748"
     CDS             3796..4785
                     /locus_tag="TU818_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL0924533.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAILVTENER
                     LLAVHMPDDGVPVADFFGQQADGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFDQKDRSAQFHTTLVVAAPGKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            4761..5282
                     /locus_tag="TU818_001749"
     CDS             4761..5282
                     /locus_tag="TU818_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL0924534.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKSYPSLSKEFKR"
     gene            5279..5740
                     /locus_tag="TU818_001750"
     CDS             5279..5740
                     /locus_tag="TU818_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL0924535.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            5737..6483
                     /gene="xerD"
                     /locus_tag="TU818_001751"
     CDS             5737..6483
                     /gene="xerD"
                     /locus_tag="TU818_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL0924536.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     KALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            6483..7190
                     /locus_tag="TU818_001752"
     CDS             6483..7190
                     /locus_tag="TU818_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL0924537.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHT
                     VIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     IEQTSHFGQIVLRKEIQ"
     gene            7187..7726
                     /locus_tag="TU818_001753"
     CDS             7187..7726
                     /locus_tag="TU818_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL0924538.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            7963..8685
                     /locus_tag="TU818_001754"
     CDS             7963..8685
                     /locus_tag="TU818_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL0924539.1"
                     /translation="MRINKYIAHAGLASRRKAEELIKRGLVTLNGQVITDLATTVKSG
                     DLVEVEGIPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEVSQLHHLASTRK"
     gene            8682..8960
                     /gene="yidD"
                     /locus_tag="TU818_001755"
     CDS             8682..8960
                     /gene="yidD"
                     /locus_tag="TU818_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL0924540.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLTRLLRCHPFAAGGEDPVPDTFSLKRHFITHEKIQDFDQKTD"
     gene            9119..9667
                     /locus_tag="TU818_001756"
     CDS             9119..9667
                     /locus_tag="TU818_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL0924541.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
BASE COUNT         2732 a         1881 c         2342 g         2862 t
ORIGIN      
        1 actgcaagtg ggctatctgc tgaggtaaac aataggtctt agtgcagcaa ggctatgttt
       61 atggttagct ctccttcttg tcttctaaaa aggaaagcta atgggcttac gacacctgat
      121 aaggggagaa agctcctttt aggctgatag ccttctgatg gtttttatgc aaaagagtga
      181 acaattttgt gatataataa gaccatgatt atcacatcaa aagcaaacca tttgattaag
      241 caggctaaga aattactgca aaaaaagcat cgcaagcact cttacttgat tgagggctgg
      301 cacctatttg aggaggctca gagatctggg caggaattga tacatatttt tgttctggag
      361 gaaatggcag agcgcttatc aggctttgat caggttgtca tcgtcagtcc agagattcta
      421 aaggagctga cgagctctcc caatccacag ggcattattg ctgaggttaa gctttgtcaa
      481 caggccttac cgactagcta tgctggaaaa tatttgattt tagaggacat tcaggatcca
      541 ggcaatctag ggacaatcat tagaacagcg gacgcagcaa agtttgatgg ggtgtttttg
      601 tctgagaagt ctgcggatgt ctacaatcaa aaaactctac gctccatgca gggcagtcat
      661 tttcacctgc cgatttggcg aacggatatt tatcaggtca gtcaggtgat gcagcagcaa
      721 aaaataccag tgctagcaac gaccttgtct caggattcga ttgattacaa ggacctctca
      781 gctaggagca gccttgccct tgttttagga aatgaaggtc agggcattag tcctgagatg
      841 gcagctttgg ctgatcagct gattcatatt agcatgcctg gacaagctga aagcttaaat
      901 gttgcagttg cagcaggaat cctcattttc agcctaattt aagctagtat ggtataataa
      961 tgatgtgagg tgattagtgt atgcattata cagaagatac agaatacatg gagcatgttg
     1021 gtcatttgat tgctcaccct cgctttcaaa ggcttggaga tattgttcag catcaccatt
     1081 ctactcgctt agagcactct gtcaatgttt cttattctag ctataggctg gcaaagaggc
     1141 ttggcttaga cgccaagagt accgcacgag gtggcttgct acacgatttc ttttattatg
     1201 attggcgagt aaccaagttt aacaagggac acgcttgggt gcaccctaga attgctgttc
     1261 gaaatgctaa aaaattaaca gcactcaaca aaaaagaaga ggatattatc ctaaagcata
     1321 tgtggggagc tactattgct tttcctcgct ataaggaaag ctatattgtt acctttgttg
     1381 ataaatattg ggcggtcaag gaggccatga cgccgctgcg tcaaaaatgg acgaaccgtc
     1441 gcttcctgcg tcgaaagacg cttcaaagtc acaatcatta agtaaaaaaa ggagttatga
     1501 tgaacgataa tgttatttac acacagtctg acgcaggctt gagccatttt tttgccaagg
     1561 tctatagcct ggttggtatg ggagttgggc tttctgcctt tgtttcttat ttgatgctgt
     1621 ttccatttag gcaaaattta gtctcgattg ttcttgatca tcctatggtc tattatgggg
     1681 cggctattgt tgagcttgta ctggtttttg ttgctagtgg tgctgcacgt cgcaatacac
     1741 cagcagcttt acccttattt cttgtctatt cagccttaaa tggctttacc ttgagcttca
     1801 ttattgcagc ttatgcgcaa acaacggtgc tacaggcctt tatctcatcg gcagctgttt
     1861 tctttgctat gtcactgctt ggtgttaagg ttaagcgtga tctgtcaggt attcgaaagg
     1921 ccatgtttgc agccttgatt gggattatcg tggctagtct ggtaaatctc tttatcggta
     1981 gtgacctgat gagctatgtg atcagcctta tttcagtgtt gatcttttct ggcttgattg
     2041 cttcagacaa tcagatgatc aagcaggtct accaagcctc taacggtcag gttggtgacg
     2101 gctgggctgt cgctatggct cttagcttat acctagactt tatcaacctc tttatcagtc
     2161 tacttcgtct cttgggaaga aatgactaat agctatttta agcgcagctg ctgattgtca
     2221 cttaatcgct attacgagaa atcagcgaag ctgcaggtgt taccttttgt tagaaaagag
     2281 tggctgctgc tagtaagaaa gtagctgcta ggagagcctg atgagcgtga ctgtcaagga
     2341 aggccagtta ctattgctac catctaggga aggtaccaaa aaaagtcaag aagcgggccc
     2401 aagggctcgt ttttgtttgc ttgatttgtg gtaaagtgct tcaaaccaag cctatatcta
     2461 gtctgatagc tcttatcagc tgacaacatc atatttacaa tgcctgttgg tgtagatttg
     2521 taaagcatgc tcttttttgg tataatgaga ggaacaaaaa atcgaggaga atatctatca
     2581 atatgtctac agctatctgg atattattaa tcattgttgc tcttacagcc ggtctttttg
     2641 gtgggatttt tattgcccgc aagcaaattg aaaaggaaat tggagagcac ccacgattaa
     2701 cgcctgaggc cattcgtgaa atgatgagtc aaatgggtca aaaaccaagt gaagcgaaaa
     2761 ttcaacaaac ttaccgcaac attgtcaagc aatcaaaagc cgcaatgact aagggtaaaa
     2821 aataggttac ggattagaaa tcgtggtttc taagcaatag ctaagagtga acagtctttg
     2881 atgttaaaag cttgtttaga gcttgcattg tcagttagag gtgtcaactg ttcaggggtt
     2941 aacaatagac tcagttggct cttaccagct gagtttttta tgcttcaatg aggaaataat
     3001 cgttatggac aatagaccaa ttggtttttt agattctggt gtaggaggct taactgttgt
     3061 tagtgagctg atgcgtcagc ttccccatga aaaaatcatt tatattggtg attcagcaag
     3121 agctccttat ggtcctagac ctgctgaaca aatcagagaa tatacctggg agttggttcg
     3181 ttttttatta acgaaacatg tcaagatgat tgtctttgct tgtaacactg caacagctgt
     3241 tgcttgggag gaggtcaagg aggctttgga tattcctgtt ttgggcgtta tcctgccggg
     3301 cgctagcgca gctatcaagg ctactagtgg aggaaaggtt ggtgttattg gcacatcaat
     3361 gactatttct tcaggcattt accaggaaaa gatccagttg ctggctccca ctgttcaggt
     3421 aactagccta gcctgtccta gatttgttcc tattgtggag tccaatgaga taagctcaag
     3481 tgtggccaag aaaattgtct atgaaacctt ggctccctta gttggaaaga tagataccct
     3541 tgttttgggc tgcacccatt atcctcttct taggacgatt atccaaaatg tgctgggacc
     3601 acaggttaaa ttgattgata gtggggcaga gtgtgtgcgt gatatttctg ttcttttaaa
     3661 ttattttgag attaatggca gtcgagatga tgaacatagg cgtcatcatt tttacactac
     3721 agccggctca gacagctttc aagcaattgc ctcagcctgg ctaaatcaaa cgatagatgt
     3781 ggagcatgtg accttatgag tgataacatt tatgaataca aggataaaga caattggttt
     3841 attggcaaga tgacaggcca taatttaatg gctggctggg gggttaacca tgagcttatt
     3901 gccaaaatag acgatatgtt aggtgcgatt gctggtgatg tggattggga aagtccggtc
     3961 ggttatgatg tgactgttat tcgttacgcc tccccttttg ccttgattag ctttgttgtt
     4021 ggcatgatca atcagaaagc caatcgagcc cttaaggttg ttcggcactc aggtgcgatt
     4081 ttagtgaccg aaaacgagcg attgcttgct gtgcatatgc cagatgatgg cgtccctgtg
     4141 gctgacttct ttggtcaaca ggcagatggc tttggggata cgattttgat tgcgactcga
     4201 aatgaaggca agaccaagga atttcgccgg ctttttggtg atatgggata tcgcgttgaa
     4261 aatctcaatg attacccaga gcttccagat gtggcagaaa ccggggtcac ctttgaggaa
     4321 aatgcccgcc taaaagcaga aaccatttca aggcttactg gaaagatggt tctggcagat
     4381 gattcagggc tcaaggtgga tattttaggt ggcttacctg gggtctggtc agctcgtttt
     4441 tcgggccctg atgctactga tgagactaat aatgctaagc tattgcatga gctggcaatg
     4501 gtatttgatc aaaaggatcg ctctgctcaa tttcatacga ccttggtggt tgctgcacct
     4561 ggtaaagaca gcttggttgt cgaggctgat tggcatggct atattgcaac caagccaaaa
     4621 ggcgagcatg gctttggcta tgatcccttg tttatcgttg gggagactgg acgtcatgca
     4681 gcagagctag ctgctgatga aaaaaacaag ctgtctcata ggggacaggc ggtcaagagg
     4741 ttaatggagg tatttccagc atggcaagca aaacaatcat tgtgatgagc gattcgcatg
     4801 gcgatcgtga ggttgtggca gctattaaag gccgttacct tggaaaggtt gatgccattt
     4861 tccataatgg cgattctgag ctagaaagct cagatcctat ttgggagggg attcatgttg
     4921 tggcaggcaa ctgtgaccat gatagcggct ataaggatag cctagtcacc tcctttgatg
     4981 gcttgactat tgctcaaaca catgggcatt tgtatcatat taactttact tgggataggc
     5041 tagattattt tgctcaggag actggagcgg atatttgttt gtatgggcac ttgcacagac
     5101 ctgctgcttg gcaattgggc aagactgtct ttatcaatcc tggctcggtc gctcagccgc
     5161 gtggtgaggt gaatgaaaag ctgtacgcgc gtgttgaatg gacagcagct tgcattaggg
     5221 tggattactt tacctgtcag cataagtctt acccatcact ttctaaggaa tttaaacgat
     5281 gatagcaaaa gaatttgaag cctttttaat cagtcatttg gatagctacc tgattccagc
     5341 agaggagcta gccattttta tcaacacgca taatgctgat catgtcatgc tcttattggt
     5401 tagcaatggt ttttcacgag ttcctgtcat taccaaggaa aagcaatatg tcggaacgat
     5461 cagcatttct gatataatga cctatcaagc caaaaggcag ctaacagact gggagatgac
     5521 gcaaactaat attggcgaca tggtcaatac aaagattgag accatcaata ttacctctag
     5581 cttgactgaa atcatgcata aattggttga ttttcccttt ttaccagttg ttaatgatga
     5641 caatcgattt atcggtatta ttacgcgtaa gtccattttg aaggcggtta atagcctttt
     5701 gcatgacttc actgatgaat acacaatcac aaaaaaatga tagcatttat tgaacccttt
     5761 ctagcaagca aatctcttgc taataacagc cagcaatcct atcgctatga tttaaggcag
     5821 ttttgccagc aggtcggaca gcgtattaat cctgaaaccc tagccctcta tcagcaaagc
     5881 ttgtctggcc ttacggtagc agctaaaaag cgcaagcttt caacggtcaa tcagtttttg
     5941 tactatttgt accagcagaa ggctttgaca gactatttta aaatggacga taggatagaa
     6001 gcctcttttt ctttgaagcc ccagctgaca aggcttgaca ccagcgcttt ttatgctgaa
     6061 acagccttcc taaaagggca gctcattgcg ctgctgattc tggagctggg cttgacgcca
     6121 agtgagatag cagggcttcg tcttgctgat tttgacctgg gtcttcaggt gctaaggttg
     6181 caatctcaca gaggcattcg tgtgatgacc ttatcaaagg ccttgctgcc atttttggaa
     6241 aaggcaacag aagctcagca gctctacctc tttgatcatg acgccaagcc cttttcaagg
     6301 caatggtttt ttaaccagct cagagatttt ttagagagca ttggctgtgc ggagctttca
     6361 gcccagagtc tgagagagca attcatttta aatgaaaaag cagccggtaa atccatcatt
     6421 gaggtggctc agctgctggg gctaaaaagc ccgatcacct tagaaaaata ttataagatg
     6481 taatggatat aaaagtaaaa gattttgaag gtcctcttga tttactcttg cacctagtgt
     6541 caaagtatga ggttgatgtt taccaggtgc ctattgtgga ggtcattgaa caatacttgg
     6601 cctatattga gaccctgcag gcgatgcgct tggagcttgc tggagagtac atgctgatgg
     6661 ctagtcagct gatgctcatc aaaagcagac gactgctgcc aaagctggta gacaaggagc
     6721 ctgatgagga ggatcttgag caagagcttt tgggtaagat tgaagaatat agtcgtttca
     6781 aggctctgag tcaggagttg gccagccagc atgacaagag ggctctgctt ttttccaagc
     6841 caaagcagga gcttatcttt gagcaggccg tcctacaaaa ggataaaaca gtcatggatt
     6901 tgtttttagc tttttcacag ttaatggctg caaagcaaga ggcctttaaa tataaccata
     6961 cggttattga gcgagatgat tatcgtattg aggatatgat ggagcttatt gaagctaggc
     7021 ttgagctaga gcaggagctt actttgacgg atttattgaa gcattgtgat catctcaatg
     7081 aggccattac cttgttttta gcaagcctag aattaatcaa acggcagctt gttggtattg
     7141 agcagacatc acattttggc cagattgttt tgcgaaagga gatccaatga cctatttatc
     7201 tcagctggag gccttgctgt ttgtcgcagg agaagaagga ctaagcctac gtcagttggc
     7261 cagcctatta gagttaacac cgacagcctt acagcagcag ctcgacaagc tttctcagaa
     7321 atacaaagag gataaggaat ctggcctgtg cttgattgag tcctctagga cctataagtt
     7381 agtcaccaaa gagtgtctgg ctcccttgct taaagactat gctaaggctc caatcaacca
     7441 aaccttgtca cgagcaagcc tggaggtttt gtcaattgtt gcctataagc agccgattac
     7501 tcggattgaa attgacgaga ttcgtggtgt caattcaagt ggtgccctta gtaaattagt
     7561 ggcctttggt ttggttcaag aggctggcaa aaaggaagtg attggtcgac caaatcttta
     7621 tgcaacaaca gattactttc ttgattatat gggtatcaat catttagaag agctggttga
     7681 tatttcttct attgctgttg aagagcaaga gacaaccctg ttttaaaggc aaagaggagc
     7741 ttgtctcatt tgcagatagg ccttatgccc tctactagaa gagataacag tcctaacaag
     7801 gtatagtgcc tgaaaatcct attgtcgtta tggacagcgg tctttttagg catgctatta
     7861 ataagagtag acctgtttaa gctagtgagc ttttacccat aggagagtga ctggtctgtt
     7921 ggagctatca tcagatttcc taataagaaa gagagaagga taatgagaat taacaaatac
     7981 atcgcccatg caggccttgc tagccgtcgt aaggctgaag agctgatcaa gcgagggctg
     8041 gtgaccctaa atggtcaggt gataacagat ttagcaacta ctgttaaatc aggcgacctt
     8101 gttgaggtag aggggattcc tatttacaat gaagagaagg tttattatct cctcaacaag
     8161 cctcgtggtg tcatctcaag cgtttcagat gataaggggc gtcagacagt gattgatttg
     8221 ctgccgcagg ttaaggagcg catttaccct gttggtcgct tggactggga tacctctggc
     8281 ttattaattt tgaccaatga tggtgatttt acagataaaa tgattcaccc ccgtaatgaa
     8341 atcgacaagg tttatctggc tcgtgtcaag ggagtggtaa ctaaagaaag cctgcgtccc
     8401 ttaacacgtg gtgtcgttat tgatggtaaa aaaacaaagc cggctcgtta ccgcattatt
     8461 cgtgttgagc ctgataaaaa tcgctctatt gttgaactaa ccattcatga gggccgtcat
     8521 catcaggtca agaaaatgtt tgaagtggtt ggacacttgg ttgataagct atcaaggaca
     8581 cagtttggca gccttgatgt cagaggccta aagcccggag aagccagaag gctgagcaaa
     8641 aaagaagtca gccagctaca tcatttagcg agcacacgaa aatgatcaaa gccctactca
     8701 ttgctcctgt cagagcctat cagaaatata tttctccctt atttcctcct tcctgtcgtt
     8761 atcagccgac ctgctcggcc tatatgatta cagctattga aaagcatggt gctaagggtg
     8821 ttttgatggg acttaccaga ctattaaggt gccacccttt tgccgctggc ggagaagacc
     8881 cggttccaga taccttttcc ttaaaaagac atttcataac gcatgaaaaa atacaggatt
     8941 ttgaccaaaa aactgattga caatagcagt taaagtgcta taatagcagt taagtattcg
     9001 ttggtttaaa tcaaacctgt tatgatttaa gttagcgagt caccgtcaac cacattgttt
     9061 gctgagcatg actccgggca gtgtggtttt tttgatgaaa agagtaagcg ggacaagcat
     9121 gaaacaagaa atcattaata gacaatatag ggaaaaagat agtcaaaacc atgtggtgct
     9181 ctttcagcca caaattccac aaaacacagg aaatattgct aggacctgtg ctgccaccaa
     9241 cacgccttta catatcatca ggcctatggg ctttccgatt gatgaccgta agatgaaaag
     9301 agcggggcta gattattggg ataagctaga cattagattt tatgatcatc tagatgaatt
     9361 tttagcacaa tgtgatggga gcttgcatgt gattagcaaa tttgctgata gggtatactc
     9421 agatgaagcc tacaatgatc gtcagtctca ttattttttg tttgggcgtg aggatactgg
     9481 tctgcctgag ccctttatgc gtcaatatgc tgatagggca ctcaggattc ctatgaatga
     9541 tgagcatgtc agaagtctca atgtctctaa tgctgtttgc atgatcgtct atgaggcact
     9601 tagacagcaa gcctttaagg gcttagagct tagccatacc tatgagcatg acaaactaaa
     9661 atcataataa gcatatcgca aaacatcagt tagattgaag aagtatccgt aggggagctt
     9721 cttcagtctt tttttattgt attctttgct tattaaccaa gcagttgaca cgaaaattcc
     9781 aatagatcgt ttaaagccaa taaaaccatt attaggc
//
LOCUS       DARYMD010000069         9389 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYMD010000069 DARYMD010000000
VERSION     DARYMD010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9389
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(7..369)
                     /locus_tag="TU818_001757"
     CDS             complement(7..369)
                     /locus_tag="TU818_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL0924542.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLIAEMVYQEQPSGDGQIAFNCGQVSYKSHKQRFIIEIKLPHQQLYQFSYPEV
                     QQASQTSKKQSELKQSLP"
     gene            complement(347..781)
                     /locus_tag="TU818_001758"
     CDS             complement(347..781)
                     /locus_tag="TU818_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL0924543.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAA
                     NDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDKKALSFGQVKGHDFRKAASNGQG
                     YQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG"
     gene            complement(768..1058)
                     /locus_tag="TU818_001759"
     CDS             complement(768..1058)
                     /locus_tag="TU818_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL0924544.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALRYSQQELSAC
                     RQKQELLNTAVMAMQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            complement(1015..1440)
                     /locus_tag="TU818_001760"
     CDS             complement(1015..1440)
                     /locus_tag="TU818_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL0924545.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLYLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            complement(1418..1741)
                     /locus_tag="TU818_001761"
     CDS             complement(1418..1741)
                     /locus_tag="TU818_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL0924546.1"
                     /translation="MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKD
                     KVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDE
                     AKKLN"
     gene            complement(1742..2728)
                     /locus_tag="TU818_001762"
     CDS             complement(1742..2728)
                     /locus_tag="TU818_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL0924547.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYV
                     TSMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLLHLPHYFLGFCLLVLLL
                     IGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELD
                     IYSQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQQMGDVF"
     gene            complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TU818_001763"
     CDS             complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TU818_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL0924548.1"
                     /translation="MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDDTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(3829..4476)
                     /locus_tag="TU818_001764"
     CDS             complement(3829..4476)
                     /locus_tag="TU818_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924549.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKISKEEGRQRELEALRAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHKNRTIIIATHSPSIWEMADEVISVDQLSSLTRL"
     gene            complement(4478..6481)
                     /locus_tag="TU818_001765"
     CDS             complement(4478..6481)
                     /locus_tag="TU818_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL0924550.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTALKPSFLGTLVLIFSSGSQALGIV
                     IFCLTFGALTLIGHIRTLRAVGIRLISGERRWQIFLYPIRSDVCYCCLGLLLGLSLAA
                     IMSQLMSFSPLVLYLIGIGLVCYNLLLIAIALFFAGLFVIGIKRVHLMQVIKGQIPVR
                     GIISLILIAQLLAVLVVSFGASRTLLYVQAERQQKQGQAAWLQEDRLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKTQAAQYQSVFESAVT
                     GLASGEGHQPMTATVSYTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLGNAILLLYRQMRIENKMSLLILKGA"
     gene            complement(7018..7383)
                     /locus_tag="TU818_001766"
     CDS             complement(7018..7383)
                     /locus_tag="TU818_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL0924551.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            complement(7444..8490)
                     /locus_tag="TU818_001767"
     CDS             complement(7444..8490)
                     /locus_tag="TU818_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL0924552.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFKQILKTYLLWSLIYLPYAYAFF
                     ESLRLPKHYLPLGLCLALSYFGMCYHLWYIPALWLGWVLVQLSLKTFGKKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHFSSSL
                     FSQRYMRKAAVCLILLALESLLIYHHQGLDKNFFLLSALFTTFLFNASVRISLLSKYS
                     LAKLKKLSYYYFFLHPMFIECSLFLLRPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
     gene            complement(9054..>9389)
                     /locus_tag="TU818_001768"
     CDS             complement(9054..>9389)
                     /locus_tag="TU818_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924553.1"
                     /translation="DRQEAIFTENSVTIRDIFSPRSFTGVNKIVFTWKGYDLYLDSTN
                     ANRLSALGWGSTALSGLIPDPIVSKVLAAALGVVSASISYANAAGRGVIVAFVGTFPR
                     GVIHWVASQ"
BASE COUNT         2967 a         2127 c         1711 g         2584 t
ORIGIN      
        1 ccttagttat gggagtgatt gcttaagctc agactgcttt ttagaagtct gagaggcctg
       61 ctgaacttca ggatagctaa attgatatag ctgctgatgt ggtaatttga tctcaattat
      121 aaaacgctgc ttatgcgact tatagctaac ctgaccacaa ttaaaggcaa tctgaccatc
      181 gccagaaggc tgctcctgat aaaccatttc tgctattagc tgagcctttg cgtagtccat
      241 ctgagcctga tattcctgat gtagctggct aatatgacta agataagcct gtaacagtaa
      301 taaaaagacc gatgccatca gcaaagcata caaaagcact cctgccttaa cccttctctt
      361 gaaatgcata aataaaggtc ctttctaagc cgctttgcca tttcagcttg atggtcacct
      421 gctgacctac tgctgttatt tggctacttg acaagccaaa cagcatgggc tgatagcctt
      481 gaccattgct agctgctttt ctaaaatcat ggcccttgac ctgtccaaag gacaaagcct
      541 tcttgtcctt ttcaacatat agcctattat tgcggacacc ctgtagggta gtacctgaaa
      601 gctctgctcg caattgctgg gaaaacaaaa gccagttgtt ctgatcattt gctgctagat
      661 acctctcatt tgccataagg ctcttggtta aggcctgata aactaataaa gagcctgaga
      721 tgacaagcaa ggcaataagg cactctatca aggtgaaagc ctttagccta ctgtctttca
      781 atcctaataa tcgtttggtc tttttcaaca atagcgatac ccttctgatg tgataatagc
      841 ttaatatgac aaccattaag gcttaatgcc ctttgttttg tctgcatagc catcacagct
      901 gtattcaaca gctcttgctt ttggcgacag gccgacagct cctgttggct ataacgcagg
      961 gctgacagta tcagtgttac aataacaaga ataagtcctg tcgctatcaa gccttcaaga
     1021 gcgatgtagg ctttgacttg ttttttgata attaccactc cctaaataaa attgataagt
     1081 aatctgccga tctctatttt caaagacaac tcttgccagc gaatggttgc cgcccagttt
     1141 atcaatggtt aaggtctggg tagattttag cttgacctgc tttggtagag gcaaaatagc
     1201 ttcttcggcc ttaatataat gtggctttaa gaccagcaca tgctcttttt gacgtaatat
     1261 cgatagcttc tgtaggtgcc tataagcctg ttcaaagcgc atgaaaaaga gatgctcctc
     1321 aaccctagca tagctatctg ataccggtag tgacaagtac agcagcataa agctaatcag
     1381 aaaaagtgtc agtaaaccct ctaagagggt aaaagcttta attgagcttc ttagcttcat
     1441 ctttatgctt tgcataataa tcctgataag ccttttgctg cttgtcactg atacttccat
     1501 cctcttgcag ctgcttcagg cttggctttt ccccatgtga taattcataa agctctgcct
     1561 gattttcaac cagctttacc accgcagcat tgcctgtgtc tgtcacctta tccttttgtt
     1621 tacttaaatt tggaacaaat aacagcatca aaacactaat gattaacaaa accagaagca
     1681 tttccagtaa agtgaaggcc tgaacacctt gatcttttaa gattgataat ctcattttca
     1741 tttaaaaaac atctcccatc tgttgataaa ttggtaataa aatagcagca taaatcatca
     1801 caataaccac agcaaccact aaaaaaataa tcggctggat ccattgtgtt gcccgattaa
     1861 gctgactaaa aaaggtctcc cagctttctt gggaatagat atctaattcc tgaccaagct
     1921 ttgatttgat gtcaccatat tcaatcatta ggcttagctc ctttttaaaa aagggataag
     1981 ctgcaaccct ttgatgaaag gattggccag ctagtagact ctgcttgata tccttggcaa
     2041 gctctcgcat gagctgtgac ttttcgtttg acatcatctc taaaatggtg attaattcta
     2101 agccttgtcc gatgaggttg ccccattctc tagcatagta ggctgtcaaa tattgccgca
     2161 ataaggaccc aatgatagga taatagctca gctgactaaa tagttttagc cgactacagg
     2221 acttggcata taggtaaaaa gagccaatta gcaacagcac aagcaaacaa aaacctaaga
     2281 aataatgagg caaatgaagc aacaagtcag tcaaggtatt ttgactctct agctgaggga
     2341 ttaggtaatg acgcaagcct agcatgataa ccactagaaa acccaaaagt ataatcggat
     2401 aagtgactgc ctcgatggtc tttcgcttga tttggcgaaa ttgactcaga tagtcctgaa
     2461 ttttttccaa ggttagcttg atattgccat gcttatctgc cagattaatt tgtgtcataa
     2521 cagcatcaga gtaacctaag gctgctagca tgtcagcaag gccgttgccc tttaataggc
     2581 ttgcttccat acttgtaaca tagactggca gtagcagctg gctttttctc aaaaaagcaa
     2641 tgacctctgt caaattaaag ccgttagaca ataggttata gagcaattgg ataagctttt
     2701 cctgctgctt actggataat tttttcaagc cttgcctgcc tggtattgag atgtccctcc
     2761 gcaagaagct gatcaatctg ctgattccac cggttggctt gatgatgttc aaattccttt
     2821 tgtgcacaat caattaaagc acctccacta ataaatcgct ggtaagcaac cattgctaga
     2881 ctattatcca attctgccct agaaatgcct aattctagca gtctagcgta aacgcctgaa
     2941 atactctttg catggacggt tgaaaagacc attgctcctg ttaggctagc cctaataacc
     3001 gctctagcag tctgtgtatc tctaatttct ccgataatca acacatctgg acgatgacgc
     3061 aaggaaagct taatcagatt atcgtatgtc atgccaatgc tatcgttaac ctgtaattgc
     3121 aggagctggt cattttttat ttccacagga tcctcaatac tgatcacctg aagctccttg
     3181 caatagtcag agactagctg atacatcagg gttgtcttac ctgatcccac cggtccagaa
     3241 aagaggtaaa ggcctctagc tccaatagct gatgtgactc gctctaaacc atcaaaccaa
     3301 tacctgagct ggcgttgatg atgatacaag agacgaataa ccaagctctc ctgtccctga
     3361 taatcaccca cagctgataa tcgtagagac accttagtgt catcaaggtc gtagtcacaa
     3421 gcaccgagct gacagcgtct tttttcgccc acattcattc ctgcaacgaa cttaaagtga
     3481 ctaataagat tagccatccg atcactttca caaacatcta ttagcctcct atcatcacct
     3541 accctcatca aaagctcata gcctgtcccc cttggtagta tataaatatc ctgagcctgc
     3601 aattcttcag cctgcctgat aagccgcttg gctaattctt gaatcattct tacctcctca
     3661 ctaagactat tcgaaaaata aaaaaaatag cctcaagaaa aaggccattt tttgataaat
     3721 gtttaacatc aagtaaggaa ttcagcacgc tacaaacagc gcagaatcct tttgcgatgc
     3781 tatgatgaca aggtcaagcc ttaatcactt agctagtcca ggctttattt agagcctggt
     3841 gaggctgcta agctgatcaa cagagatgac ctcatctgcc atttcccaaa tgcttgggct
     3901 gtgggttgcg atgataattg tccgattttt atgccgaagt gacagcaaaa tagccataat
     3961 tgccttagaa gcctctggat caatagaagc cgtaggctca tcagctaaaa taaagggagg
     4021 atcttttagc atcaccttag ctagggcaac acgctggtat tcaccaccag acaattcaaa
     4081 aacaggcttt tctaagctca gataatccaa gccaactgcc cttagggctt ctaattccct
     4141 ttgccggcct tcctccttgc ttattttttg accaattagc cctagcttca aattatcagc
     4201 aatcgtctga ctctccaaca gcccaaaatg ctgaaatagg tagcccaatt cgtgacggaa
     4261 aaaatcgctg gatctgtatg ttttcaagtt ttttccacga aagaaaatct caccctgata
     4321 atcctcaaga gctgccagca tattcatcaa ggttgtctta ccactaccgc ttgacccaat
     4381 cagggcataa acctttccag actcaaaggt cattgacaaa tcagaaaata agacacgatc
     4441 accaaagcat ttactaacct tttctaatcg aatcatacta agctcctttc aaaatcagca
     4501 gcgacatctt attttctatt ctcatttgcc gatatagtag caatatggca ttccctagaa
     4561 ataggaagaa aaccagcagg cacataagag gattctgtgt taacagggca ctaatcacca
     4621 atccaacaaa gaaaacaagc agctgcgaca gcaaataacg acgatgcagc tcaaaaaatc
     4681 taagaccaga gacgcgctta atgaaaatat cccgtctaaa ttcttcaaag tagagaaggt
     4741 tcattgtgtt aaacatcaac atagaggtcg ctatccctaa tatagctcct gcaatcatca
     4801 accaaatctc cctacgaaga ttgttcaaca atgtctcata aatgcgatag ccagttttta
     4861 gctctcctac ccagttctca ataccgtttt gcttgatgag cgtttgagta tctgccaact
     4921 gatcgaaaag gaaataattt tgtaaagcaa cctcccaaaa ggcataggct tgttcgccag
     4981 ttgacttagg cgtcaaaaca acaataatgg gatcccttaa aaactgctga taggatatcg
     5041 gtgttgtgtt ataaagaaag cgttcctggc ctgtctttgt ataagaaaca gtagcagtca
     5101 tcggctgatg accctcacct gaagcaagcc cagttacagc tgattcaaag accgattggt
     5161 actgtgcagc ctgtgttttc aaatgctctg gtaaaagaag gacaaattct ccaagggaca
     5221 gctgattgat tttttcacta atatcaggtg ccacctcaac tttttggtgc ttcacatatt
     5281 gaggcgttac aagcagcaca ttcccttgtg gactgtaatc attccaacta gaagaggctg
     5341 ttagcataga gaggcctgat tgcaggtcgc gctcgactag gtaatgacga gacaggatcg
     5401 ctccatgctc tgaaacagcc tgatccataa catgaaacca agtcttttgt ttggcaatag
     5461 cttccttcgt atttccaata tctaagccat cacgtcctat taaaagagta accagcctat
     5521 cctcttgtag ccaagcagcc tgcccctgct tctgctgtct ttcagcctgg acataaagaa
     5581 gggtccggct agcgccaaag gaaacaacca gcactgccaa caattgggca attaaaatca
     5641 agctaatgat acctctgaca ggtatctgac ctttaatcac ctgcatcaaa tgcactcttt
     5701 taatcccaat tacaaataaa ccagcaaaga aaagggcaat agctatcagc aaaagattat
     5761 agcaaacaag acctatccca atcaggtaaa gaacaagcgg tgaaaaagac ataagctgac
     5821 tcataatagc cgccaggcta aggccaagta gtaggcctag acagcaatag cacacatcag
     5881 acctgattgg ataaagaaag atctgccagc gacgttcacc tgaaatcaag cggataccca
     5941 ctgctcgcag cgtgcgaata tggccaatca aggtcaaagc cccaaaggtt agacagaata
     6001 tcacaatccc taaagcctga gaaccactgc taaaaatcaa aacgagagtc cctaaaaatg
     6061 aaggcttcag cgctgtcatt ttggtcatac cgagcccagc taatgtgtct cttagtcgct
     6121 ctacagtcaa gccgccttta agaataaagt aattattctc cacactaagc cttgatggtt
     6181 cctcaataac cttttcagct agtccaccag gtagctttcc cttgccaaat aaggtatagg
     6241 tcacaatagg tgtaccttct ggccctggct cctggtgctg cattgcaatt aagctgtctg
     6301 tttcatctgc tagacgggtt aagcctgctt caacctgatt atagcttgcc ttaggcgaag
     6361 catctaaaac aacaacagac ggataataat gagaaacaaa ggtatctgac cagatcgtaa
     6421 atacccaaac caaaaagagg ctaactagta tattagacaa tatgataaac agtctcttca
     6481 taacccactc cttaccttaa aagggacgga gtctctccgc ccctaataaa cacacactga
     6541 cctgcctatt tccctgcatc aaaggtcacg tgctctccaa aattagtatt gataaaagca
     6601 taggagtagt aaccagcacc agaccatgca cgcctctgat tatcacgtcc tgagctctcc
     6661 acaaaggacc ggtgagaaga ggtcagaagg tcacctattg aaaacgcctt caatcataaa
     6721 ggacatggcg attaccacaa taccactcaa atcattaact atttaacaaa aatataccat
     6781 attctgttaa cgtttacaat gttatattta atccattttt ataaaaaaat aacattatat
     6841 catgcctcaa atgattttat cataatgagg ctcgctatgt tgttttctct atcccaatca
     6901 ggcactgcta gattagacat ctttccagac aacaaaaata gcctaaggtc agctctctaa
     6961 ttagctgatc ttaggctatt tgagtgataa tagatttgac tgatagctgt aagcctctca
     7021 gatgcttaat ttacagctaa gggaggcttg tgggcagtca tttctttgct caaaatatga
     7081 ctgataatga tgctttggca caatgtctct atcctttagc aataaaagag agtgatactg
     7141 ctgcagctcc tcatcgcaat cctcacacca tcttcgctca tcttccctcc aaaaggtagc
     7201 caataagctt ttttgactgt ggtagctggg atagctcttt ttcatgcgct gccattcttc
     7261 ctcaaaataa gccagtgcag caggccagct gtcaaacgat ttctcctgaa caatatcgtc
     7321 ttgccaacca tctataaacc accaaggctc ccagtctcca tacatttcaa tcacttgata
     7381 catgttctca tttcctctat tgcctattat agccgaagaa agatattttt aaaaaacatc
     7441 tgctcactgc cttttaagat aggccttggc atgagcttga gaacgtacca gcagcataag
     7501 ggcctctgag caaagatgag tagctagcag ggtcatgaga aagaccagtt tcccttttgt
     7561 ggccggggca agctggtagg gccttagcag aaatagcgaa cattcgataa acattgggtg
     7621 caagaaaaaa taataatagc ttagcttttt taatttagct aaagaatatt tagacagaag
     7681 gctgatacgg acactggcat tgaataaaaa ggtagtaaac agcgcagaaa gcaagaagaa
     7741 atttttatcc agaccctgat gatggtaaat aagcaggctt tccaaggcca ataagatcag
     7801 gcaaacagcc gcctttctca tatacctctg agaaaaaagc gacgatgaaa agtgatcata
     7861 gagcaagcag cccgcacaaa gataagcagg ggtgtaaaaa ataccattgc gacttgtttg
     7921 aaaaatgtgc atgtagcctg tcagcaaagg ctcaaaaggc gtcgagctta aaaaatgaga
     7981 ataggtttcc atactcccta gtaaatacaa gcccgccact atgatgagcg ttaccttctt
     8041 accaaaggtc ttcagagaaa gctgaacaag cacccacccc agccataaag caggaatata
     8101 ccacagatga tagcacatcc caaaataact aagggctaaa cacaagccaa ggggaagata
     8161 atgcttaggc agacgaagcg actcaaaaaa ggcataagca taagggaggt aaatcagaga
     8221 ccaaagcaaa taggttttta gtatttgctt gaagtactgc ttttcccgat tcgcctctct
     8281 aaggcggcct cttagaaaaa aggcggtaca aatgagaaaa taaggcaccg ccattcttcc
     8341 taaaaagctt ttcaaaaaga aatgcagcgg ctcatactga aacagcctac cgctatgaat
     8401 aacaataacc attatggcaa aacagtattg taacaggctt accacagagg tattgaggct
     8461 gtcagtgact ttctggctct cttttgtcat caattcaatc actttctttt aagagattaa
     8521 tatacgtata acttttagta tttatcgcat ttgtctctca ttttgattaa tattgttttt
     8581 atcatagcgt aatataacca attaatctaa tgattttagc ataacaaaag gagctaaggc
     8641 tagctcctga acatcacaaa agagcagacg aacttcatct cctctcgtgc ttagatataa
     8701 gccacccact acagttaaca tggagccata aaacgaagga attaactcct tcgttttctt
     8761 tcaatttttc ttggaatatt tttatagact tttcttacgg atatagtaag aataactacc
     8821 agcaataatg acataattca ataaaagaca taattaatca caacttgatt gtctttctaa
     8881 caaatccatt ccctgcctgg atcattagta tacgaaaaaa atgataggta aaactatacc
     8941 caataggcag aaaaaaactt tccaaaaaat agtattattt ttaaataatt tatcaacaaa
     9001 caccaataat atcaaattaa ttgctaaaca cagtattttt aaatataatg ctatcattgt
     9061 gaagccaccc aatgtatcac acctcttgga aaagttccta caaaggcaac aattactcct
     9121 cttcctgcag cattagcata agatattgat gcagacacaa ctcctaaagc ggctgcaagt
     9181 accttagata ctatagggtc tggaataaga cctgacaaag cagttgatcc ccagcctagt
     9241 gcagataatc tattcgcatt ggtactatct aaataaagat catagccttt ccaagtaaaa
     9301 acaattttat ttaccccagt aaatgatcta ggactaaata tatctcttat agtaacagaa
     9361 ttttcagtaa aaattgcttc ttgtctatc
//
LOCUS       DARYMD010000070         9170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYMD010000070 DARYMD010000000
VERSION     DARYMD010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            101..1027
                     /locus_tag="TU818_001769"
     CDS             101..1027
                     /locus_tag="TU818_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL0924554.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKAGKELTVACNALMHQGMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            1135..2421
                     /locus_tag="TU818_001770"
     CDS             1135..2421
                     /locus_tag="TU818_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL0924555.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKDDLIDELWKVAQRELATGFYYHIPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(2517..2842)
                     /locus_tag="TU818_001771"
                     /pseudo
     CDS             complement(2517..2842)
                     /locus_tag="TU818_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2977..3189
                     /locus_tag="TU818_001772"
     CDS             2977..3189
                     /locus_tag="TU818_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL0924556.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(4085..4225)
                     /locus_tag="TU818_001773"
     CDS             complement(4085..4225)
                     /locus_tag="TU818_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924557.1"
                     /translation="MKKEYISYLSAAIFILYALLSLKWIFFVLGVILLIIGLADRFRS
                     KP"
     gene            complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TU818_001774"
     CDS             complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TU818_001774"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL0924558.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDD
                     NYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIAPELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVTGID
                     FWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            6424..7901
                     /locus_tag="TU818_001775"
                     /pseudo
     CDS             6424..7901
                     /locus_tag="TU818_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            8213..9118
                     /locus_tag="TU818_001776"
     CDS             8213..9118
                     /locus_tag="TU818_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL0924559.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINRAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQATGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVILLRLNKQQERVLRMKYANR"
BASE COUNT         2533 a         1729 c         2097 g         2811 t
ORIGIN      
        1 ttttttttga aggcttctcg ttataggcct tggtataggc gttaagattt tgaatgaatc
       61 atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa taattattac
      121 agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg ttgatcgtat
      181 ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt atgatgactt
      241 gaggcagatt gcagcgcttg ttcacaaggc gggcaaggag ctaacagttg cttgtaacgc
      301 tctgatgcat cagggcatga tggatcgtat aaagcccttt ttggacctta tgaaggagat
      361 tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata aacgagatgg
      421 ctacgacttt aagctgattt atgatacttc ggtttttgtt acctcaagcc gtcaggttaa
      481 tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc cctcggagga
      541 attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt acggggcctc
      601 tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta ccaaaattga
      661 tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc ctgatagtca
      721 ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg acattgatat
      781 gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc tagatggtgt
      841 ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag caaaggcttt
      901 gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag aagtgcaagg
      961 gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc ctaaaacagt
     1021 caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc atgacaagtt
     1081 aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa caacatgtca
     1141 aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa attaaaggtt
     1201 gccattgatt atggcgctga tgcggttttt gttggtggac aggcctacgg gctaagaagt
     1261 cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc tcacaagtat
     1321 ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaacga gcttggggct
     1381 ggtgagtggt tccgtcaatt gcgtgatatg gggcttgatg cggtcatcgt ttcagacccg
     1441 gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct atcaactcaa
     1501 gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct aacgcgtgtc
     1561 gtgctagcac gtgaggtcaa tatggcagaa ttggctgaga ttcgaaagcg cacagaggtt
     1621 gagattgagg cctttgtaca tggtgccatg tgtatttcct attcagggcg ctgtgttctc
     1681 tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc ctgccgctgg
     1741 aagtatgatt tgtatgatat gccttttggc tcagagcgtc gttccttaaa aggagagatt
     1801 ccagaggaat actccatgtc ctcggttgac atgtgcatgc tggagcatat ccctgatttg
     1861 attgaaaatg gagttgatag cttgaaaatc gaagggcgca tgaagtctat ccattatgtg
     1921 tcaacagtga ccaattgcta taaagcagct gttgatgctt atatggaaag tccagaggca
     1981 ttttatgcta ttaaggacga ccttattgat gagctttgga aagtggctca gcgtgagcta
     2041 gcaactggct tttactacca tattccaact gagaatgaac agcttttcgg tgcgcggcgt
     2101 aagattccgc aatacaaatt tgttggggag gtggtttcct ttgatgatga cagcatgaca
     2161 gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt ttacggaccg
     2221 ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg caataaaatt
     2281 gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc tgtcaagcca
     2341 ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa ggacggaacc
     2401 agtaagacca taagagccta gcaccactag actaagcaat aggatttgac caattacttt
     2461 tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta ctgagtctat
     2521 ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc aatatctgct
     2581 aaaaaaataa tgcagtcagg ttttgattgg tattttttaa gaccaattga ccggttagct
     2641 gatcgtattt tttaatgtgc ccagtgaagc ttttggcttg atagatcaca tgaattggaa
     2701 tctccttgac ctgtgcctct ttgatggtgg taatgatctg gttggccttg aggttaacgg
     2761 gagaagtctt ggcttttttg ggaggctgat tgtcaataaa gccgatcaag gctgattgca
     2821 gctgcttcat cattgatttc atagctattg tcctcaaaca ttgatagaat agtttgatag
     2881 tattttacct taaactatga tttttaaaaa gaatttactg ttttgcattc aatttttaat
     2941 attattttcg aatagataga tgaggaggaa aatataatgt cagaatttac atttaagatt
     3001 gaggagcatt tgctaaccct gtcagaaagc gataaggggt ggacaaaaga gctaaaccgc
     3061 gttagcttca atggagcaga gccaaaatgg gatatccgca cctggagccc tgatcacaca
     3121 aagatgggta agggcattac tctgaccaat gaagaattta agacaattct tgatgccttt
     3181 cgtcgttaag ccttagctta gtcatcaata acttcaatgt gagaagaacc ttttctaacg
     3241 aacagtatca accatcagtt actttgttct tgtaggaagg ttcttttgtt atctcttcaa
     3301 gtgagttttt aagagcaagg taaaagacta tcgtctagaa cccccttagc attcatagct
     3361 gctaccgcaa cgataaaagt taaaaaacaa actaactggg gatctggtat ctagaaagtt
     3421 aatctagtcc tcttagagct tttagtaact gttagtcact atttattggt gagaggaata
     3481 tatcacaatg ctccaatcga gccttggttt gggtgtttta agtccggatg ctatgagcta
     3541 aagtcatacc agacttgtga agagcctatc actgatagta atcgctatct ctacttttac
     3601 aatgatagtc atctttaaaa gcacatgaaa ggccctgccc ctcctttaag gaggaacaag
     3661 gcttctgttt aatcattatg agattagtat tcgcttaata ggaagtcact caagctcagc
     3721 gtctattttg agactgatgc ttctgtccta gccttaggct gctcatattc tgctctaaaa
     3781 tcatacggat tgtcctgatt tgctttagaa tagcatactt gttgagtcta ggtcccaagg
     3841 atcttgaatg actgacgttg aaggtgttta gctcctgtta tcttggtata agaaggtatg
     3901 accttttggt aattggattg tctattgtat ggttccaaga tgatgattgg catgcttggt
     3961 tgttgactgc aagctgatag ccttgtggga ggctttgctt tcataaggct taagggctat
     4021 ttttacttta atgtaaggct ccttggctgg cagctatcga gacttggaga tgatagaggg
     4081 ctagctaagg ctttgacctg aaacgatcgg ctagaccaat aatcaagagg atcaccccta
     4141 aaacaaagaa aatccatttc aagctgagta aggcataaag gataaaaata gcagctgaga
     4201 ggtaactaat gtattctttt ttcataagat gctccctatc tttttatact attgtagcat
     4261 aaaaatcagt ttaaatgctg atgaaatcaa tggctatttt ggctttcatt ggcctagtaa
     4321 aaaccgttta gcctagcagc atgtcatcat tgcaaacaaa aaagattgaa gaatcaagtc
     4381 taagagatga ttcttcaatc ctagtataca gacaagctaa ggacatcact tcaaaagtga
     4441 ggcttttaga gaagctaaag gcaactaatg actattagct aggcctagct atggaagtga
     4501 ttggtcatag tgatcattcg atctggataa gaggcttagg atcagctaga gaaagctgct
     4561 ttttaaacac tggtagctag tcgcttttta tggcttcatt gttgggaata acaaaacatc
     4621 gcgaatagtg gttgtatttg tcagcagcat gcagaggcgg tcaataccga ttccaagccc
     4681 gcctgttggt ggcataccgt attcaagagc ctcaacgaag tcgtagtcaa taccggttgc
     4741 ttcatcgtct ccaagctcct tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
     4801 tggatcattt agctcggtaa aggcattagc atattccttt gtcatgataa agagctcaaa
     4861 gcggtctgtg aagcgactgt cctcagggtt tttcttagca agcggtgaaa cctctacagg
     4921 gtgcccatag acaaaggttg gctgaattag ggtgtcctcg acaaatgcct caaagaaggc
     4981 attgatgata tgaccaacag aggtaaaatg cttttcaact ggcacatgct tttcgttagc
     5041 aagagctgtt gcttcctcaa aagtcatctc aggccagaag tcaataccag ttacctcctt
     5101 gatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
     5161 ataatcaatt ggtccctctc ccttgactgc tttagcagcg tgctgaatga ttccttcagt
     5221 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
     5281 tgggttatgt gtagcgtcca tcccttcatt acgaaagatc cgtccaattt catagacacg
     5341 ctccatgcca ccgacgatga ggcgcttgag atgcagctct ggtgcaatgc gaagcaccat
     5401 atcgatatct tgtgcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
     5461 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcgaggt aacgacgaat
     5521 ttcagaaatc atttttgaac gtgtgatgaa ccgttcaaag ctgctgcggt ttgaaatcaa
     5581 atccagatga cgcttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
     5641 tagcggacgt agagatttgg atagatgggt cagttttgtg gccttgatag acaactcacc
     5701 catatcagta cacataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttttt
     5761 gaaaatgtca tagttgtcat caccaactga atccttacga acatagattt ggatttgccc
     5821 ttggcgatcc tgaagatgag caaagccgac ctttccttta ccacgcttgg tcatcagacg
     5881 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
     5941 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
     6001 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
     6061 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
     6121 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
     6181 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
     6241 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
     6301 atgatatttg acaaaaaaac ttaaattgtg aaaaaatatt aatcgaaaaa atcaaaaaac
     6361 tctcaacgct aaggctagtc tttgtgcagt tgagggtttt tatcaggaaa ggatcataaa
     6421 gaaatggaaa cttatgatat acacgggaag ccttatcatc gaacgctgat gattatattg
     6481 ctgttggtgg gaacctttgc aggggtttta aaccaaacaa gcttggggac agctatacca
     6541 acattgatgg aaaattttaa ggtacctttg tcaacaactc agcaggcaac cacttggttt
     6601 ttgcttgcta atggcattat gatccctgtt tcggcctttt tagcaacgcg attttccact
     6661 aaaagactct acatgacagc ttatgctatt cttgtgagtg gcttgttact agcagctctg
     6721 gctccgactg ctcattgggg agttttttaa cagcacgtat cgttcaggct tgtgcagtgg
     6781 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
     6841 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
     6901 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggctggcggg
     6961 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
     7021 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
     7081 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
     7141 atatggtgta cgtgatttta cctattttag tcggtattgg tggaatttac ctcttttcca
     7201 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
     7261 ttaccttgac aacaatagca attgccctaa cgatgatggc tatgatcggt gttgagatga
     7321 tgctgccgct gtatctgcaa aatgtcagag gcttatctcc attaaattcc ggaatggttt
     7381 tgttgccggg tgctttgatt atggggctga tcagtccagt ttctggccga atttatgaca
     7441 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
     7501 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
     7561 gaatgtttgg catatcaatg attttaatgc ctttaactgc aagtgctatg aatgccttgc
     7621 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
     7681 ctattgttgt ggcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
     7741 ctaaaatgct cctatccata caccctgagc aatacgctaa gaagcttcta gaagccaatt
     7801 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
     7861 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gctcctgatt agtgtggtta
     7921 aaacaaatag gctaaaggcc tcacgccaaa cgcatgaaaa aacagctgtt tttgatagct
     7981 tttctgatta atgcactctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
     8041 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgagtct agaaaattgt
     8101 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
     8161 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
     8221 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
     8281 aatggaaaag tgctttccag attttgatat gtcattgatc aatcgagcct atattcgttt
     8341 tcgccattat tctgacgttg gatttccaag agtgatgtca ggtgagtgga cgacagaata
     8401 ttttcgattt tggcggtgtc gggagaccct gcttgagttt ggctatcgtg acattgatca
     8461 ggcgacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
     8521 tgatgagatg cgcatgacac ttgatttctt gaagtcaaaa aacgttccga tggggattat
     8581 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
     8641 tgttgatcct aagcgcgtga ttgtcagtca ggcgacaggc tttcaaaagc cagaaaaaga
     8701 gatattcaac ctagcagcag agcagtttga catgaaccct gcaacaaccc tctatgtcgg
     8761 cgactcttat gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
     8821 taaccacaga gggagaagtc taaagcctgg gacaaggcct atctatgatg tggccattga
     8881 taactttgag cagctgtttg gtgctgttaa ggtcttgttt gatctgccag acaacaaggt
     8941 tatttttgat atcaacgaca agaaaaaccc ggtgctgcaa ttaggactta acaatggttt
     9001 gatgatggca gcagagcgct tgctagaaag taacatgagt attgataagg ttgttatcct
     9061 gttacgcttg aataagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
     9121 gttattgatt gaaaagcatg ctatgtttaa ttggcactcc aaaggctaga
//
LOCUS       DARYMD010000071         9131 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYMD010000071 DARYMD010000000
VERSION     DARYMD010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9131
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            4..594
                     /locus_tag="TU818_001777"
     CDS             4..594
                     /locus_tag="TU818_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0924560.1"
                     /translation="MEGITKSYGAKLILKDFSYTFEQGKKYLIKGASGRGKSTLLHII
                     KGTAVDSGKIAFITKDNHSFESYQANIGMVSQAPFLFNGTLEENICLNQEFSKENILA
                     VLDQVHLLEELPAGLGFQIENNGTNISGGQRVRIELARFLLRQKDILLLDEVTAALDK
                     DNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIEL"
     gene            604..2166
                     /locus_tag="TU818_001778"
     CDS             604..2166
                     /locus_tag="TU818_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924561.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTFLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNYREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGHSTLIQNQALFASLKQVKKQSEHYESS
                     RQAFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDMFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGSSGSGKSTLFKLILQEMSPDEGTLDMVLTGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNHQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVKNAKTIRQLLFSLPVTVIEIAHQID
                     DTFIYDGDIDLS"
     gene            2549..3650
                     /gene="prfB"
                     /locus_tag="TU818_001779"
     CDS             join(2549..2620,2622..3650)
                     /gene="prfB"
                     /locus_tag="TU818_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL0924562.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            3701..4393
                     /gene="ftsE"
                     /locus_tag="TU818_001780"
     CDS             3701..4393
                     /gene="ftsE"
                     /locus_tag="TU818_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL0924563.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            4386..5315
                     /locus_tag="TU818_001781"
     CDS             4386..5315
                     /locus_tag="TU818_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0924564.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKMVQSINGEQINNENYHKIYDQIAGLKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLFGAILPSLIIYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGMLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(5705..6346)
                     /locus_tag="TU818_001782"
     CDS             complement(5705..6346)
                     /locus_tag="TU818_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL0924565.1"
                     /translation="MTIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHADLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            6683..>9131
                     /locus_tag="TU818_001783"
     CDS             6683..>9131
                     /locus_tag="TU818_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL0924566.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIVEGKEIVDSYQT
                     DINPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLYETAMIVRQALAVSRPYSTSDYIKINQIL
                     LKKPDQLTKPYQLSQSFEINAALLGLEERPKQLSFAKIVEETLFQTEPAFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNQLDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRFAAYFDQIKHDGSI
                     QQTSPFYAYDFWQQSYQRAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAVPSSLLEQRLLEGIAFELNQLSSHYHQEEEKQQA
                     QASQHLLRLQEHVKELGAAASQSLKQLFKQQEMDYWVSSEQQADKRQTFLNGSSRTVL
                     QFKALLPEIFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMP
                     LIKDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGK
                     NGTAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQ
                     RYLQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILH
                     SLEEEFLISQQNFQDSLA"
BASE COUNT         2579 a         1814 c         2097 g         2641 t
ORIGIN      
        1 gctttggaag ggatcacaaa gtcctatggc gccaagctga tccttaagga tttttcctat
       61 acctttgaac aggggaaaaa atatttgata aagggtgcca gtggtagagg taagtcgact
      121 ctgttacaca ttattaaggg aactgctgtt gactcaggta aaatagcgtt tatcaccaaa
      181 gacaatcact catttgaaag ctatcaagct aacattggca tggtgagtca ggcacctttt
      241 ctctttaatg gcaccttgga agagaatatc tgtctgaatc aggagttttc caaggagaat
      301 atccttgctg tcttggacca agttcacctg ttggaggaat taccagctgg tctaggcttt
      361 cagatagaaa ataatgggac caacatttcg ggcggccagc gagtgcgcat agaattggct
      421 cgatttttgc tacgtcagaa ggatatttta ttgcttgatg aggtcacagc agccttggac
      481 aaggacaatg ctcggcgagt aagggagctg attttttctc ttcctattac catcattgag
      541 gtggctcatc atgtggatca agctatagct tatgatgata tgatagaatt gtaggtgatt
      601 aagatgttta agtattttaa taaatatcta gtgacactaa cgcttgttgc atgtgcctta
      661 aacagtcttg tctttctgat tgaacccttg atcactagta agatttttga tttaacgttc
      721 ttaaataatc atcaagacac cttgtccttt ttaggctatg gtctgacctt atacgtggtc
      781 ttatattctg ttatgttcat tgctaatctt ctgatcaacc atatcatgac gattgggtgt
      841 ggtagaatca ggttgcgtct ctatcagaat ttaatcttaa attatcggga gatgagtcat
      901 gacaagaaaa tttctatgct gactcaagat gtagaatatt atctatggaa tcacatcagc
      961 cctagcattc ttctcgtatc acacgtgagt aatgtccttt tgctcagtgc ttacctgtta
     1021 tcaaaaaaca tgctaattgg tcttattttt attgcatgtg cttttgtatt tttagtggtt
     1081 cagcatgtga ttggtcaaaa ggcagagcaa aaaggtagtg agctggcagt agcgagacaa
     1141 aagctgcttg gcttattaag tgatgtggtt gcggggcatt cgacattaat tcaaaatcaa
     1201 gctctttttg ctagcctcaa acaggtaaaa aaacagtcag agcattatga gagctcacgt
     1261 caagcatttg agatatttag gtctttcttt accctattgg cacatctgat gctgtttatt
     1321 tctcaattct tgcccatttt tttaggctta gccttaacct tattaggtgt taagctgaga
     1381 acaactgatc ttattgccat gtttattgca gcaacgcgct tagaacagcc actcaaaaat
     1441 attgttgatg atatgtttag gcttaatggt gcaaaagcca ttgctaagca ttttgagaca
     1501 cttttagagc agcctattcc aaaataccag tcgcatgcta tgacaggtga tccttttgaa
     1561 tgcttagatg gtcatcatct ggcgaaatca tttgcaggta ggaccttatt ttccgatctc
     1621 tcttttcatt ttgagaaggg aaagaaatac ctgattaagg gatcaagtgg atctggtaaa
     1681 tccacactct ttaagcttat cttacaggag atgagtcctg atgaggggac actagatatg
     1741 gtattgactg gaggtcagac gactgataat tatcaccatc gcatagggct gattgcgcag
     1801 tcgccttatc tttttaacga tagcattcgg tataatttga ccttggggga ggcgttttct
     1861 gatgagttgc ttttagaaaa gctagaacag gttggcttga ctgatgaatt tgacgatatt
     1921 ttaaaccacc aaattgttaa taacggagaa aatatctcag gtggtcaaaa gacacgtctt
     1981 gaaatcgcaa gaagcctcat tagacaaaaa gatgttcttc tagcagatga agtgacggct
     2041 ccacttgatg tcaaaaatgc taaaactatc cgacagctac tatttagttt accggtaaca
     2101 gttattgaaa ttgctcatca gattgatgac acctttatct atgacggtga tattgattta
     2161 tcgtagaaaa tatcatcaca ttgcttagaa ataataattg atgcttatga aattgtcatt
     2221 cacacagtga atggcttttt cttaggctaa attttccatg tggagcttga tctgataggc
     2281 tatctgagaa aaaaagctaa caacagccat gttttttggg gctatgactg ttctaatacg
     2341 agctgcctct agctgctggt atataagagg tgacatgatt gtcacaattc gtcatcattt
     2401 tgtcgttaaa tttttacata gatttcttat gctagtcatg gcagagctcc ttaccctaaa
     2461 aagaagggaa tttagctgat gggaaatagc aattctaaag cctttatgat aaaatgaaaa
     2521 aagacactat aatagaagag gtaactgtat ggaagtggca gaaatgcgcc agcaaatagt
     2581 agaaaacaaa gagaagttga ctagcttcag gaggtctctt tgacttagag cgtttggagg
     2641 aggatatagc tctcttagaa aataagatga cagagcctga tttttggaat gataatatgg
     2701 cagctcaaaa aacctctcag gaattaaacg agctcaagct cacctatcaa acctttcatg
     2761 atatgcagga gctatctgat gagacagagc tttatttaga aatgcttgac gaggacgata
     2821 gcgtcaagga agagctagaa gcaagcctga ttaagctcag ccagatgcta gcaagctatg
     2881 aaatgacgct gcttttgtct gagccctatg atcatagcaa tgcaatccta gaaattcacc
     2941 caggttcagg tggcactgaa gcacaagact gggcagacat gctttttcgc atgtacactc
     3001 gctttggaaa tgccaagggc tttaaggtag aaactctgga ctatcaagca ggagacgagg
     3061 caggaattaa gtctgtgacc ctttctattg aagggccaaa tgcttatggc ttcttaaaat
     3121 cagaaatggg agtacatcgt ctggtgcgta tttctccttt tgactctgct aagcgtcgtc
     3181 acacctcctt tgtttcagtt gaagtcatgc cagagcttga tgataccatc gaggtggaga
     3241 tacgtgatga tgacattaag atggacacct tccgctcagg tggtgctggt gggcaaaatg
     3301 tcaacaaggt ctcaactggg gtacgcttga cccatatccc aacaggaatc gtagtggcgt
     3361 caacagttga ccgcacccaa tatggcaacc gtgatcgcgc tatgaaaatg cttcaagcca
     3421 agctttatca gttagagcag gagaaaaagg cagaagaggt caatgccctc aagggggata
     3481 aaaaggagat cacctggggc agtcagatca ggtcctatgt ctttacgcct tatacgatgg
     3541 tgaaggatca tcgtaccaat tttgaggtgg ctcaggttga taaggtgatg gacggagata
     3601 ttgagggttt tattgacgct tatctcaaat ggcgcatggg tgaggattaa agtgatcccc
     3661 actcagataa acactaacag cttagagaag gaagaataag atggcattaa ttgaaatgaa
     3721 gggtgtttct aagaaatacc gtcgctcgac aacagctctg agagacatta atgtctcagt
     3781 caatcaaggg gaatttgtct atattgttgg tccatcagga gctggtaaat caacctttat
     3841 caagcttctt tatcgcgaag aaaagctaag ctcaggcagc ctaaaggtgg gtgagtttga
     3901 cttaaccaag ctaagaggac gtgaggttcc aattttacgt cgcagcattg gtgttgtttt
     3961 tcaggattat aagttgctcc ctaaaaaaac ggtctttgaa aatgttgcct atgctatgga
     4021 ggttatcgga gagagacgtc gccatatcaa aaagcgtgtt cctgaggttc tagaccttgt
     4081 cgggttaaag cataagatgc gctcctttcc caatcaattg tcaggtggtg agcagcagcg
     4141 tgttgcgatt gcacgcgcta ttgtgaacaa tcccaagctc ctcattgcag atgagcctac
     4201 aggcaatttg gatccggaaa tttcttggga aatcatgcac ctgcttgagc gtatcaatct
     4261 acaggggaca acgatattaa tggcaacgca taacagtcat atcgttaata ctcttcgcca
     4321 tcgcgtggtt gcgattgaaa atgggcgtat tgtccgcgat gaggagaaag gagactatgg
     4381 ttacgatgat tagacatttt ttccgtcata tctgggaatc tatcaaaaat ttaaggcgta
     4441 atctcctcat gacctttgcg tcagtcagta tggtgaccgt caccttaacc ctgcttgggg
     4501 tctttgctgc aaccctgctg aacattcaac gtgtcgcttc tggcgtggaa aacaacattc
     4561 aaatcaatgc ttacttacag gttgattcga cagatgctgc taagatggtt cagtcgatta
     4621 atggagagca gataaataac gagaattacc ataagattta tgatcagatt gcagggctaa
     4681 agggtgttga gaggattatt ttctcaagca aggacgagca gctgcaaaag ctacaggata
     4741 gtctgggcga tgtctggggc atgtataatg aggatagtaa tcctctgcaa gacatctata
     4801 tcgtagagac caagacccct aagcaggtca aatcagttac caaggccatc aaaaagattc
     4861 aagggattga agatgcggac tatggtggta ttaattctga taagcttttt aagttttcaa
     4921 aactgattca aacatggggg attatcggaa cgctgttgct cctgtttatt gcgatctttc
     4981 tgatttcaaa taccattcgc atgaccatca tgtctcgtca gcgcgatatt gcgatcatgc
     5041 gtctggttgg tgcgaaaaat tcttatattc gtggcccatt cttttttgaa ggggcttggg
     5101 ttggtctgtt tggtgcgata ttgccatcgt tgattattta ttatggctac gagtttgcct
     5161 acaagcattt caccccggaa ttacagcata atagcctgtc tatgtaccct atcaatccat
     5221 atgtttatta tttaattggc atgctttttg tgattggtat tatcattggg tcactaggat
     5281 cagtcttatc tatgagacgt taccttaagt tttaattgaa agagcttcta gcctgtgtgc
     5341 ctggactggt accctgcggt tagggctctt tttgcttttg gggcaatgct tgctagataa
     5401 gcaaacaata gcttaagccc ataccattaa gtattgggct taagctattg ttatagttgt
     5461 ttaggtaata gaagcagccg gaacttgagg tgtcctatct aggtcttgag ctatagcttt
     5521 tctggctagt tggtgtttct tcacgtaaca gcgatttgtc gaacgataag gtgctcttct
     5581 tgtgatagct ggcttgtagt gatcgacagg tgctaagtca aattagccat cctgatggac
     5641 tggagtcata gcttttgctg ctgcgcctgg ttgggcatag actgggcatc tcggtagctt
     5701 gagcttatcg ctgcctcaga aagggattgc tatttttttc atggctaatg gtggtagctg
     5761 agccatgccc cggataaatc tgataatggt taggaagtgt tagcagctta tcacgaatgc
     5821 tagcaagcag ctgttcaaga tttccagtcg gcaaatctgt tctaccgatg ctttctctaa
     5881 acagagcatc gccagtaaac accgcctcct cctgctcaaa gataaaggaa acgccaccgg
     5941 cagagtgtcc tggtgttggc actactgaaa agtgaaatcc agctagctga taaggtgtct
     6001 gatactgaaa gagcttttct gctggtttgc agatgatatc aggcagatca gcgtgacgta
     6061 tcagtcctga caggttcatt tctggtttat aaagccagtc cgcctcctcc ttggcaacat
     6121 agacaggagg gtgctggcag ctctctctca ccagctctag gctcataatg tgatcataat
     6181 gcgtatgggt cagtaggata gcagcaacag gcttgttgat ggcatggatt tgtgataaaa
     6241 tagcctgccc cttgcttcct gggtcaatga ctaaaatagc ctcgtcattg acaagaaggt
     6301 aagtgttttc acccgcaacg ggattcatca gtgtcataat agtcataccc ttagtttacc
     6361 aaaatctgac tcaaaagaca gctcaaaacc acctcttttg ataaaagtga tctgtttaat
     6421 ggttttgatg gctaagccaa gatagctcca gcttaaaggc tgcttttttt aattaatagg
     6481 agcaaaaagg agctgcctca gcgctaacag ctaatcagag tattagctct ctagtgtcat
     6541 agcaaggaag taggctgggg cgattaaaag gcttgataac tagcttttta tgatactgac
     6601 tagccctatt gagctgagct aagactggta ttgtcagatt taggcaaagc ctgtcagaaa
     6661 acgtgctata atagatagta ctatgatcaa tgagttttca caaaaatatg ctgtgattga
     6721 cctggaagcc actagcccag gtccaacagc gtctattatt caggttggca ttgtgatcgt
     6781 tgaaggaaaa gaaatcgttg attcgtatca aactgatatt aatcctcatg agcccttgtc
     6841 agaccatatc aaagcactca caggtattac agaccagcag ctagctcagg caccggattt
     6901 ttcacaggta gcaaggacca tttttgagct gattgaggac tgtgtttttg ttgctcataa
     6961 tgtcaccttt gacgccaatt tgttggcaga agccttattt ttggagggct atgatctcct
     7021 cactcctaga gtggatactg ttgagctggc tcagattttt taccccagcc tagaaaaata
     7081 cagccttagc cacctatcag aggtgctaga cctaaaccta tctgatgctc ataccgctat
     7141 tgctgatgct caggcgactg ctaacttatt tatcaagctg cttcacaaga tagagagctt
     7201 gccaagagaa tgcttggaga ctcttttgct gtatgctgat agtctgttat atgagacagc
     7261 tatgattgtg agacaagccc ttgcagtcag tcggccttat tctacgagtg actacatcaa
     7321 gattaatcag atcttgctaa aaaagccgga tcagctaaca aagccctatc aattatccca
     7381 gtcctttgag attaatgcag ccctcttagg tcttgaggag cgccccaagc agctcagctt
     7441 tgcaaagatt gttgaggaga ctctttttca gaccgagcca gcctttatcg aggctcaggc
     7501 aggcattggt aaaacctatg gctatttact gcctctcctt gcacagaaac atcagaccca
     7561 aatcttggtt agtgtgccaa ccaagctgct acaggaccaa atcatggcta atgaggtgag
     7621 ggctattcag gagcagtttc acatcgattg ccatagtatc aaggggcctg ctaattacat
     7681 caagctagac agctttcaag agagcctcaa tcagcttgat gacaaccgct tggttaatcg
     7741 ctataaaatg caattgctgg tttggctttt ggaaacaagg actggtgatt tagatgaaat
     7801 caagcaaaag caacggtttg cagcttactt tgaccagatc aagcatgatg gcagtatcca
     7861 gcagacctcg cccttttacg cttatgattt ttggcaacaa agctatcaaa gggctaagtc
     7921 agctcgcttg ctgatcacca atcatgccta ttttttacac cggattcagg acgataaggc
     7981 atttgccaag ggtaagattc tagtctttga tgaagctcag gccttaatgc tgcagctaga
     8041 ggagctagct catcagcgac taaatatagc tgatacgctc caagagcttc aagagcagct
     8101 agctgtgcca agcagcttgc ttgagcaacg cttgctagag ggcattgcct ttgagctcaa
     8161 tcagttaagc agtcattatc atcaggagga ggagaagcag caagctcaag cctcacagca
     8221 tttgctgcgg ctccaagagc atgtcaagga gctaggtgct gcagcctctc agagcctcaa
     8281 gcagctgttc aagcagcagg aaatggatta ttgggtgagc agtgagcagc aggctgacaa
     8341 gcgccaaacc tttttaaatg gcagcagcag gacggtcctt cagtttaaag cattgctacc
     8401 ggagattttt aaggcctact ttgtctcagc tactctacag attagcccta gcattagctt
     8461 ggctgattta ttgggctttg acacttattc ttatcatcag ctggctaagg agaaaagcac
     8521 tcagcaattg gttgtcattg accaagacat gcccttgatt aaggacttga ctgacgaggc
     8581 ttacacacag accatagcag caaggctatt agtgcttcat cagcaacagc aggtacctat
     8641 cttagtgctc tttaatgcta aaaagcacat gctcatggtt tctgactatt tagaggctaa
     8701 tcaggtgcag cacttgacac aaggcaaaaa cggtacagcc tatcacatca aaaagcgctt
     8761 tgatcgtggt gagcaatcaa tgctgctggg gcttgcagcc ttttgggagg gagttgactt
     8821 tgttcatgct gatcgcatga tagaggtcat tacccgcctg ccctttgata atccagaaga
     8881 tattgccact caaaaaatgc agcgctacct acaggcagca ggtaagcagc cctttaatga
     8941 ttattttctg ccgatgacga tcttaagatt aaagcaggcg attggtcgaa ccctgcgtcg
     9001 aaaagagcag aaatcagcag ttttgatctt agatcgtcgc attctgacca tgtcctatgg
     9061 tcagaccatt ttgcacagcc tagaagagga atttctgata tcacaacaaa atttccaaga
     9121 tagtctagca g
//
LOCUS       DARYMD010000072         8581 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYMD010000072 DARYMD010000000
VERSION     DARYMD010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8581
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            46..288
                     /locus_tag="TU818_001784"
     CDS             46..288
                     /locus_tag="TU818_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924567.1"
                     /translation="MISCTLLASLLLTGCHSLSLQLAEAVQEKPIQAVTVEDLTRHGI
                     AESLKAYLQTMGLTNEEAMKQYEEVLSDEIIQYFSS"
     gene            complement(410..1624)
                     /gene="thiI"
                     /locus_tag="TU818_001785"
     CDS             complement(410..1624)
                     /gene="thiI"
                     /locus_tag="TU818_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL0924568.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVDGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(1626..2768)
                     /locus_tag="TU818_001786"
     CDS             complement(1626..2768)
                     /locus_tag="TU818_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL0924569.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVDVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKVGKPAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            3008..3448
                     /locus_tag="TU818_001787"
     CDS             3008..3448
                     /locus_tag="TU818_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924570.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            complement(3518..4870)
                     /gene="gorA"
                     /locus_tag="TU818_001788"
     CDS             complement(3518..4870)
                     /gene="gorA"
                     /locus_tag="TU818_001788"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL0924571.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKKGYIAVDAYENTSVDGIYAVGDVNGKLALTPVAVAAGRRLAERLFHNKPNEKL
                     DYNKVATVVFSHPPIGSIGLTEEAAIQAYGQAAVRVYQSQFTSMYTAITSHRQPCLMK
                     LIVAGEEETIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(5064..5405)
                     /locus_tag="TU818_001789"
     CDS             complement(5064..5405)
                     /locus_tag="TU818_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL0924572.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            complement(5466..6632)
                     /gene="aroC"
                     /locus_tag="TU818_001790"
     CDS             complement(5466..6632)
                     /gene="aroC"
                     /locus_tag="TU818_001790"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL0924573.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAMSFADIKKVAESSDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETLIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            complement(6745..7425)
                     /locus_tag="TU818_001791"
     CDS             complement(6745..7425)
                     /locus_tag="TU818_001791"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL0924574.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSQEGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            complement(7422..8534)
                     /locus_tag="TU818_001792"
     CDS             complement(7422..8534)
                     /locus_tag="TU818_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL0924575.1"
                     /translation="MQLLDEKDFDGTIWDYQLVQLVNSSHQLIGTAYLSKQHKGVGWY
                     LGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQDGDDFGGLTIDLYKDFA
                     LFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDKETAHLYGAFAPDTFTIL
                     ENGVAYQVFLNDGLMTGIFLDQHEVRRGLVDGLALGKTVLNLFSYTAAFSVAAAMGGA
                     VETTSVDLAKRSRELSKAHFVQNQLDLSSHQLVVMDVFDYFKYAKRKQLSFDLIIIDP
                     PSFARNKKQTFSVSKDYHQLIAEALDLLAPKGTIIASTNAANMTVNQFKKQIIKGLGG
                     RPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
BASE COUNT         2510 a         2049 c         1610 g         2412 t
ORIGIN      
        1 tcatataatt ttcatgaaag gagggaaata tatgaaaaat ctatattgat aagttgtaca
       61 ctattagcca gtctcttatt aactggctgt cactcattgt ctttgcagct agctgaggct
      121 gttcaggaaa agcctattca agcggttacg gtagaggatt tgaccagaca tggcattgcc
      181 gaatccttga aagcctacct acagacgatg ggcttaacca atgaagaggc tatgaaacaa
      241 tacgaggagg tcctttctga tgagattatc cagtatttta gcagctaaat aagagaattt
      301 gagcaaaatc agctaaaaac aaaagccaga gcctttaata actaataggt ctggcttttt
      361 ttgactgttt agatagactg cttatgttgt agggctaggt gcgcacctcc tacaacaatt
      421 cctcaataag cgttgataag ctgtcagttt cgatttcagg agtgatctca gttactctga
      481 tccctgccac tgctcgctcg accaatccgt cgacatcaaa gcgagactca tatcgttcaa
      541 catttgctag cttgggattg gttttgggac gatcaggagc aaaaatagta cagcagtctt
      601 caaagggctg aatggaaata tcaaaggtgt caatttgctg agcgatatca atgatttcta
      661 gcttatccat tgccacaact ggtctgataa tcggagttga agtgactgca ttaatagcct
      721 gcatgctctc taaggtctgg cttgcaacct gtcctaagct ttcaccgtta ataatcacta
      781 aagcctttcg cttctcacga atagcatctg tgatccgcag catgaagcgt ctagtaagtg
      841 tcatcaaata ggcttcgggt gccttatgct tgatctcctc ttgaatctcg gtaaatggaa
      901 cctcgataaa ctgtatatta cctccaaaac gtgttaagcg ctgcgttaga tccttggctt
      961 ttcttagcgc accaggactg gtatagggtg ggcttgcaaa atgcactgcc tcaatctcaa
     1021 cacctcgttt cagggataga tagcccgcaa ccggtgaatc aataccacct gatagcatca
     1081 gcattccctt tcctgaagct ccaaccggca gccctccagc tccctttata tcttcgtgag
     1141 acagataagc agcctcatca cgaatttcga cctttagggt aacatcagga tttttcatct
     1201 gtgccttgat atgcggcaaa gcctcaaaga cggctgctcc taaggtgtgg ttgaggtcgc
     1261 ggctatctag ctcaaactga tggtcactac gcttgctgga tattttaaag gttagccctt
     1321 cgcgatacaa ggagctcata atctcctgaa ctgctgctat cagtacaggg acactttttt
     1381 caactttata gacaggagat aagccctgaa taccaaacac cggctttaag gcttcaatca
     1441 cagacctatc atctgcacca ttaagtaaaa catgggtcct gtctcgagtt gatctgactg
     1501 tcacctcaga ataggcagaa agaacatctt gaatattagc ttttagccga ttaataaacc
     1561 gcatacggtt ttttcccttg gtcgataact ccccatgacg aaccattatt tctgaatatt
     1621 tcatattatc taaccttttg tgttttttca taaatctgtt taaaaatcgt taaaaattgc
     1681 tcaacctgtc ccatatcatt atcatcatct aggctgatac ggactgctgt ttgagccaat
     1741 gctgctggaa ttcccattga gactaaggtt cctgccggct ttccaacctt tgatgagcag
     1801 gcactcgttg ttgatatata aatctcatgc ttttcaaatg cgtgcacaat aacctctcca
     1861 cgaacgccct ttataccaaa ggtcagaata tgaggagcaa aatcatctat ctcagaaaag
     1921 agaatggtat cctcataggc ctgcaaggct tgataaataa cctttttcat ggctgctatc
     1981 cttgcttgag atctatcctg tctttctgtg atgatcctta aagccttggc catacttgca
     2041 atagctgcca cgttttcagt tgtcgaacgt agctcatctt cttgaccgcc accgaccaat
     2101 aagggagtga ttcgctttcc tgatttttta taaagaaagc caacaccacg aacagcatga
     2161 aatttatgac cagaaaaaga agctaagtca acacgcgcgg ttaagtaagc ctcaacagga
     2221 agcttcccaa tagcctgaac agcatcgaca tgaaaggtaa tggtgggctt atcagccaaa
     2281 agctctgata tggctgcaat cggctgaatt gacccaatct cattgttaac cgccataatg
     2341 gaaactaata tggtatcttt tcggattaag gcagctagct ttttgacatc aacaactccc
     2401 ttatctgtga caggagcata agacagctca aagccttgac tttctagcca tttggcgctt
     2461 tctctgacag ctgggtgctc aatggctgag acaatgatgt gcttaccaaa gtgagatttt
     2521 tcaaaggcaa tccccttgat agcccaattg tcgctttccg ttccgccaga ggtaaagaaa
     2581 atctctttgg cctctacatc aagtaaggcc gctatttgcc tgcgcgaagc ctccaatata
     2641 cgactggcat tggctcctag ctgatggaga ctagagggat tgccgtaaat cttactggcc
     2701 acttcctgat acgttttaag tgcctcttcg taaggcttgg tagtggctgc attatcaaaa
     2761 taaatcatgt gtcaccttca tttttattca atactttatt gtatcacaaa tttgatgaaa
     2821 tgaaaaaata gatctttttg caggatagga caactctatc ctagacaata aggtaaaccg
     2881 ttgacttgat ttttgttcta gattatactg gtagatgata gagctaagtc tgaaatgcct
     2941 gttagccatt aaagacctaa agcatttgac tttagctagc ctatgactcg ttaaaggaga
     3001 tattctcatg tcatcacatt attcacgtca acaaaagcct aaaaaatcag caagtattcc
     3061 cacaaagcat attaaaactg gctttaccgc ccttcaaaaa accattgcct tagttggtag
     3121 tgttctgagt attgttgtag cgacaatcac tattaatcga gctctacaac catcaaatga
     3181 gcaacccaaa agcgattcct ctccgtcatc aacatcaacg attgtgaaaa ttattgaaaa
     3241 ggagtcgtca cactcaaata aggaagagac tgacaagaca gaaactaatt ctgattctag
     3301 cggtactcag gcgacacata ctactcctag ctcagctgat cctgctacta aggatacaga
     3361 aaaacaacag aataccgaaa cggaagcacc ggctgctaat caacccacag ctaatgagcc
     3421 agctcctaac agtacaagca atccataaca caaaacacga taacaggcaa ttcagataag
     3481 ctctgaattg tctgctatcg tgttttatca tgtgctgtta tctcatggta acaaactctt
     3541 cagcacctgt agggtgaatg gcaacagtat tgtcaaaatc agccttagta gcccccattt
     3601 taatggcaac agcaaagcct tgaatcatct catcaacacc ataaccaata ccatgcagac
     3661 caacgatggt ctcttcttct cctgcaacga tcaatttcat taggcagggc tggcgatgac
     3721 tagtaatagc tgtatacatg gacgtaaatt gtgattgata gacacgaaca gccgcttgcc
     3781 cataggcttg aatagctgcc tcttctgtta agccgatcga gccaattggc ggatggctaa
     3841 agacaactgt cgcaaccttg ttataatcaa gcttttcatt gggcttatta tgaaacaagc
     3901 gctctgccaa gcgacgacct gctgcgacag cgactggggt caaagcaagc tttccattaa
     3961 catcaccaac agcatagatg ccatcaacag atgtgttttc ataagcgtca acagcaatat
     4021 agcccttctt atccagctca actcctgtat gctccaagcc aaagcctgtc acatttggct
     4081 tgcggccaat tgcccaaatc acttggtcca cttcaagcct acgaccatcg gacaaatgca
     4141 cttgaagaga gccatcatta gccttggtaa ccttagtaac atcggcattg gtatgcagcc
     4201 ttggtccaga taccttcatc tcatcgacca gaacctggat aatatcctga tcaaaggtcc
     4261 tcagtggcct gtcatagcga accagcaaat ccgtctgaga acctagggca ttgagcactc
     4321 ctgcaatctc aacagcaata tagccagcac cgacaactgc tgttcgtttt ggaatatcat
     4381 ctaaagcaaa gaaaccatct gagctaatcc ccagctcagc tccttcaatg tcaggaaaaa
     4441 taggctgacc accagtagcg attaaaatat ggggggctgt ataggtctta cctgcaatgt
     4501 caaccgtatg ctgatcaata aatcgtgcat aatcataaat acgatcaacc ccgttatgct
     4561 caaagccctt ctcataagag gcatgaatac gatcaatata ggcctgacga ttgcttttta
     4621 aggttttaaa atcaaaccta tcctctaaca ccgtaaaccc gtaatccttc gcataggtat
     4681 gaatcgtttc tgctacctgt gcgccatacc acatgacctt tttaggcacg cagcccaaat
     4741 taacacaggt ccctccaata gccttgccct cagctaatag gaccttagca ccgtacattg
     4801 ctgcacgatt cgccgaggca atcccagcgc tcccaccacc aatcacaata taatcatact
     4861 gaattgccat taatttacca cctttactct taatgcttgc ctcaatagat ttgttattaa
     4921 gctatcatta ttgctttatt ttaatctact gtcatttgac tataacataa aataacttgt
     4981 gtctcaaatc cctgctacga caaaaaaaga ttgtgataag catcaacaat cctttcttct
     5041 cttaatccta agccagctta gctctacttg gccaaatcct tcaatggtgc aaatacaatc
     5101 cgttcaatat cattaacata gacggaaaga gcctgctgag cgttaaaata cccttttaat
     5161 aggtcattgg cctcaatttt ttggctgaga gcctgaatat ctgcctgctc tgtctctgtt
     5221 ggcagctgac cggtctgcat gagtccttgc aatttttctt gcacagcaac aaactcatca
     5281 aatagctgac tggcagcctc atctgcctta atctcttctc tggcttccaa ggccttgcga
     5341 tactctggga gcgcacgaac agctcgctca agcttattgg cataatcata aatatcttgg
     5401 gacatctgga tctcctttta tcatttatta tccttatcat atcacaatat caagccattt
     5461 gtcgcttaaa aatgatgaac atagtcacga taggcaaaaa aagcctgctt taaatcggtc
     5521 atattgtctg atggaaattg ttccaaaatc tcttttgtga tgacagttgc tacaacattt
     5581 tccatcacga caccggcagc cggcagagcc gtaggatcag aacgctcaac agtagccttg
     5641 taaggctcgt gcgtctcagt atccacagac attaggggct tgtagagggt gggaatcggc
     5701 ttcatcaccc ctttgacaac aataggctga ccagtagtca tacctgcctc aaagccacct
     5761 agtcggtttg ttcgacgact gtagccgctt gtctcatgcc aaatgatgtc gtccatgacc
     5821 tgcgagcctt tttggtagcc catgtcaaag cccataccaa attcgacccc tttaaaggcg
     5881 ttgatagaca ggacagcctg cgcgattttg gcgtctaatt tacgatccca ctgaacatat
     5941 gaacctaagc ctgctggtaa gccatgaatg agtgtttcaa taataccacc aagcgtatct
     6001 ccttcttttt tgacttgatc aatatgggcc ttgatagtcg cctcttgctt gggattgaca
     6061 atagataaat cagaagactc tgctactttt ttgatatctg caaaggacat cgcctcaggc
     6121 acagctacct cgataccacc aaaaactagg acatgattag cagtttcgat cccaagctca
     6181 gtaaggattg ccttagcaat tgcaccaacg gccacacgca tcgctgtttc tctggcagag
     6241 gagcgctcaa gcgcatttct taaatcatca aaacgatatt tgatcccccc aaccaagtca
     6301 gcatgaccag ggcgtggacg agtgatttta cgcttgaact tgatttgctc ttcaacagcc
     6361 tcaacagcca taatgtctag ccatttttga tggtccttgt tttgaatggt taaagtaatt
     6421 ggtgctcctg ttgttttgcc atgacgaaca cctgaagaga tatgcacacg atctgattca
     6481 atgcgcatgc gtgcgccacg accatatccc ccctgccgac gcttcagttc cttgttaata
     6541 agctcagctg ataatgctaa gcctgcagga attccctcta taatggccgt caaagcttgt
     6601 ccatgtgact cacctgctgt taaatacctc attattcctc catttatcaa tcatagacat
     6661 aaaaagcaaa cctgccctcc tctagacaac taaaagacat tattctaagc tatccaagag
     6721 aataatgtct gttaccgtat cttatcaatc ctcagattcc aaaacatgaa gaatcctttt
     6781 catatcagcc aaggaaacct gccctggtgc actggcttga tctaaggaca caaaagtcca
     6841 cgaggaccct acaacatcac ctgccaagcg tgatagtctg cctagctttc ccattgacat
     6901 ggttgcaaat tcctgctctg ggttaagtgt tttaaagcct ctggtataat tcatcaaatc
     6961 caaaacgtcc tgctcgctct gtggcatgac agcaatcttg acaacgcgag gagctagctt
     7021 agtcatctcc gaaaaagcct ccatcagatt ttcaggcgtc tcatcaaaat tgtgataaga
     7081 caagacaaga ttcggaaagt caagcatttc atgaaagaca gccttgtgac taaagtattc
     7141 aaagtcaata tagtcaggat tataaatcgc attgatctcc ttgatcaaat caacgtattc
     7201 ctgatcagaa agtgtaatat gccctccttc ttgacttgta cgaagggtaa aaataatctc
     7261 tctacctgca aatttttcaa aaatagctgg cgctacagaa acaatatcct ccttaggaag
     7321 aaagtctgct cgccactcga ttaaattaac atcttgatat ttagaaacgt cgatagattg
     7381 agcctcttca acatttcttg gcatgactgg tgctacaatt ttcattctcg tacccttata
     7441 gtaaatacct ttaaataatt acttctttca tctgctttat tgatagtaaa atcacttgga
     7501 agctgctcaa gtgtcatctg agctaatggc ctgcctccca atcctttgat aatttgcttt
     7561 ttaaactggt taacagtcat attggcagca tttgttgaag cgataattgt tcccttgggg
     7621 gccaataggt ctagagcctc agcgattaat tgatggtaat ccttactcac tgaaaacgtc
     7681 tgctttttgt ttctggcaaa gcttggtgga tcaataataa taagatcaaa agaaagttgc
     7741 tttcgcttag catacttaaa atagtcaaaa acgtccataa ccacaagctg atgactggat
     7801 aggtccaact gattttgaac aaaatgagcc tttgataact ctctggagcg ctttgccaaa
     7861 tcaacagagg ttgtctcaac tgcaccgccc attgctgcag ctacagaaaa agctgctgta
     7921 tatgagaaca ggtttaaaac agtctttcca agcgccaagc cgtccaccag acctcgtcta
     7981 acctcatgct gatcaagaaa aatccctgtc atcaagccat catttaaaaa tacctgatag
     8041 gctacgccat tttctaaaat ggtaaaggta tcaggagcaa acgcgccata caaatgagcc
     8101 gtctccttat ctggtccctt aaagcgaatc ttttcataag ctcccctgac ctcaggaaaa
     8161 acctctcgaa aagcctgaat aataagctcc ttttcttgat aaacaaagac attataccaa
     8221 gaaaataaag caaagtcctt atagaggtct atggttagtc ctccaaaatc atcaccgtct
     8281 tggttaaaaa gacggtaagc atttgtccat tcagacgcgg caaaatgctc tcttttcttc
     8341 ttagctgtct taaataaggt cacaaaataa gaaaccgaca atttcttaac agaccttcct
     8401 agataccagc ctactccctt atgttgcttt gaaaggtaag ctgtgccgat gagctgatga
     8461 gatgaattca caagctgcac taactggtag tcccaaatgg tgccatcaaa atccttttca
     8521 tctagtaatt gtatccctgc tgctatcttg cgttcaacaa ggggattaat acagacctta
     8581 t
//
LOCUS       DARYMD010000073         7717 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYMD010000073 DARYMD010000000
VERSION     DARYMD010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7717
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..405
                     /locus_tag="TU818_001793"
     CDS             <1..405
                     /locus_tag="TU818_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL0924576.1"
                     /translation="GRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPMSADGHRPV
                     SERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPIDEAVTQAEE
                     QIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            414..1085
                     /locus_tag="TU818_001794"
     CDS             414..1085
                     /locus_tag="TU818_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924577.1"
                     /translation="MISFKNISKTYQVGDQEVKVLDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            1102..3375
                     /locus_tag="TU818_001795"
     CDS             1102..3375
                     /locus_tag="TU818_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0924578.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISTSHLPTVWVQATNLTKQDIEKIEALNQVSKVRPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDLRDDIENILGNKLVSYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALSGLLVSPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLTVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVD"
     gene            3850..5871
                     /locus_tag="TU818_001796"
     CDS             3850..5871
                     /locus_tag="TU818_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0924579.1"
                     /translation="MITKKQRKLKRHTTIRRLCHQALAATLITGSLMGTGLLGNKVVY
                     GDMKSDAKKVLATLQKGNHKQELKKVLRTIGDDSLLLLWLLVSGDSNLDESNKSFDYL
                     SIWNTGSRVGKVISPTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEATEALNQKA
                     QLEATVKNINEELEKTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKEKA
                     EAEAKKAKEEAKTAEGKVKQAETEKRNAEAKARTAEEEAKQATADKEKAETEAKKAKE
                     EAKTAKEAAHQEQEKAKQLEQANQQANQRANLAEKSKKDLETQKEKLEQEIKEATEAK
                     NKAEQKLKDLQDSASQGSELSKQLLKEKEELTTKLQELQKQAEEKTTEIEKLKQELEA
                     NKQNSGQLGQQEQKLQEQLNKVQKELKQKEMELKQAQEQLKQEQKPHEGGGDSDASKA
                     RITELEKQVQTLTKEKADLSSTLESTKAQLSETQARLSEAQKQLTAAQEKLTTLEAEK
                     TALQHQVETISKQLSETRDLSEKEKAALQEQINKLKAEIEQKTKEIEALKQGMQSHQG
                     QEKPKDPKTPETPKDPKTPEKNDQPQAPEKRSVPWTALTPAKPIDTTKAPKSSAPSPQ
                     TGAATPKKQLPATGDTATPSFFTAAAMAVLASVGVLNLSPRRKKNQNNR"
     gene            6288..7130
                     /locus_tag="TU818_001797"
     CDS             6288..7130
                     /locus_tag="TU818_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL0924580.1"
                     /translation="MVSVLSRVIKGIIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFVENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQVDWLWLVLTFVLSGLGLYFLNDLVGTIPASFTAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLVGTFLPIAIGGLLTMLAFSKIMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNKEAISYAGAGLGTWLMALLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(7233..>7717)
                     /locus_tag="TU818_001798"
     CDS             complement(7233..>7717)
                     /locus_tag="TU818_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL0924581.1"
                     /translation="FKPGEVSFPSGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEI
                     DYLVQPTRSIHCFVAELAIDDWRRLRVNEEVDSLFTVPLEELMAQAPVAYPLQMQSII
                     SSDFPLDRIPNGEQYRLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDI
                     "
BASE COUNT         2553 a         1595 c         1541 g         2028 t
ORIGIN      
        1 ggaagaggct tttataaaaa atacatgaat gcctatgggc aggtggcaag gctgcattct
       61 cagcaatggt acaccgatgt cgttcatctt cctgttgaat ttcctatgtc agccgatggg
      121 cataggccag tctctgagag gtaccggaca ctatcagaca aagaaatcag agaaggcttt
      181 ctctccattg gaaaaacacc ggagcttgtc agtggcagtc aggtcgagag attgcgaaaa
      241 atcattaacc tatatgacct gccggttgtc gttccaattg acgaggcagt cactcaagca
      301 gaggagcaaa tcagaaccaa cagagaagct gtctccaagc ggattattga gcagtataaa
      361 gagccttcat taaaagaaaa aataaaattt atatcagaat tttaggagtg tagatgattt
      421 catttaagaa tattagcaag acataccaag tcggagacca agaggttaaa gtattagacg
      481 atgtttcctt tacgattgaa aagggaaggt ttactgttat tttaggcccc tctggttcag
      541 gaaagagcac gctcttaaat ttacttggag gaatggaccg ggcaagcaag ggaaccttta
      601 tctttgaggg taaggacatt acagccttaa atgataaagc attatctgat tatcgcaaag
      661 aggttgtagg ctttgtcttt cagttttaca atcttattcc aagcctaaca gccttagaaa
      721 atatcagtat cgccgcacag ctaaccggaa acacagcaca atcagaggta ttgttggata
      781 aggtggggtt atctcatcgg aaaaacaatt tccctagcca gctgtcaggc ggagaaatgc
      841 agcgcgtatc catagccaga gctctggcaa agaagccaaa attattgcta tgtgatgagc
      901 ctaccggtgc ccttgattcc aaaacagggc agcacattat gcagctactt caggaagcgt
      961 caaaggacga ggacgtagcg gttgtcttgg tgacacataa cactgaattt aaagcttttg
     1021 gcgataccat tatttaccta aaggacggaa agataagctc gattgatcat aaacaatcag
     1081 tttagaggat tggagctaaa catgaaatat cttaatttaa agctaaggcg agatttaaag
     1141 catcattggc agcaattctt ttcagtgttc ttgatgtcct tattaagtgt tttaatcttt
     1201 gttggtctac agggtgcttg gcatgggctg gaaaaaagct tagacaacta tatatctacc
     1261 tctcatttgc caaccgtttg ggtacaggct actaatctaa caaaacagga cattgaaaaa
     1321 atagaggcct taaatcaagt cagcaaggtt agacctaaga ttagggtcac tgctgctatt
     1381 gattctgaca gcgacctaga gcattactta acgctagatt cattacagtc tacctcagat
     1441 caggtgacac gtgttgtagc tggcgaggcc ttttcaacca aagaaaccga taaagtatgg
     1501 ttgaacaagg aatatgctga cgctaaccac ctatccctcg gtgataagat cagcttaaca
     1561 ctatcaggtc aatcaattag tgtgactctt gcgggtcttg tccagtcagc agacaggatc
     1621 tactttacag gcagcttaga gtatatagct cctaattatg ataactatgc ctacggctac
     1681 atctcaaaaa agagcttagc taagctcctt cagacgcagc tgcctgataa tatggttgac
     1741 atttacgcct cgtctgacga tcttcgagac gacatagaga acattttagg caataagctt
     1801 gtttcttatt acaatcaaac aaccctaact gacgtctctg aggcagttga tagagtagga
     1861 cagattagga atctctctta tttgttctcc tttatcttca tcttactagc tattctatcc
     1921 atgtttacca cgatcagacg tctcatcgaa agtcaaacaa aggaaattgc tatcatcaag
     1981 gccttaggct attctaacat acaggtcagt ggccactaca tttcctttgg cttgttggtt
     2041 ggaacattag gtgctctttc tggtcttctg gtatctcctg ctatgtcctg gtttgtccta
     2101 gagacccaaa agagaatgtt ctcacttcct aagtgggaaa ttgcttactc tctgtcttcc
     2161 ctagtagttg cattactggt ggttatgatt tgtgtgacat ctgcttactt tgcttctcga
     2221 aaagccatta aagggctgcc agcagtattc ttacgaggaa aaaacaggga cgtcaagcat
     2281 attttgctcg aaaaaatcaa gcccttatgg cgtagtattt ctgacgaagc taagtgggct
     2341 atacgtgatg ctttgacaca ccgcatcaga attttaatgg ggattatagg ggtagctggt
     2401 agtatgatgc ttttaattgc cggtattggc atgcctatct ctatgaatca ccttgttgat
     2461 aaggcctata acaaggactt tagctactcc aaacgcttga cggtttctga ctacgaatcg
     2521 gccaataagg cctataaagg ccaatgggtg caaatcaatc aagcccactt ctcaaaagat
     2581 gacggctaca atcgtctctt gattattatc agcaagggaa gccttgttaa cgccaccaca
     2641 gaagatggtg acaagataaa agagggtggt ctctatgtta ccaacagctt tgccaagcta
     2701 gccaatatca aggttggaga caagctatct gtcacaccct accaggataa gcatcagtat
     2761 acctttagtg ttaagggaat tctgaccagc gaaactaatc aaggtgccta tatcatggct
     2821 gataccttca aaaaagcagg cggagctttt cacccacaca cattgttagt agataagcaa
     2881 gtttctgctt ctacaatcgc tcaggatcag aatgttttaa ccgtcattga taagtccagc
     2941 caagaaagca atgcctatga ccttgtcaat agtctaatga gtgtcttttt gatgatcatt
     3001 ggctttgcct tgctgctagt catcgttgtg ctgtataatt taggctcttt aaattttgta
     3061 gagcgcacaa gagactacgc aacccttcag gttctaggat tttcaaaaag aaatctccaa
     3121 aacataacaa tgctcgaaaa tctcatgaca acctctgtgg gctggctctt gggaattcct
     3181 atggggattt ggtttttaga gcagtatgtc gccaccttct ctacgatacg tcttgaatat
     3241 acggcttatg tcacttggca ggttctgcta gcggcaagtg tccttgtctg gctaacatca
     3301 ttaatgacca ctcttttcat cagtagaaag attagaacaa ttgacatggt tgatgcctta
     3361 aagggagtcg actaacctca ctttatcaca tacctgactc tctctctttt atggttaagc
     3421 atcatcactg cactggttct gatatgatga ctgataaagc tgtaattgtg ctgtaacaag
     3481 cactgtcatt acatagcaac acccttaaaa acaagcatca gatttggtgc ttgtttttga
     3541 atttattgct aatgctaaac gcaacgatta tcacaaatca tgcagtacac gcttataaca
     3601 gcttaagcat gcccattatt caaaaaacgt tgatcaaaat gacttccctg aagtttagat
     3661 cattcctcaa tttattgata caaatgtgat aaagtcatac gatcttcttg tttattaaaa
     3721 aaaaaaaaaa acgaaactac ggagagaaag atgagctttg tcgtttctca cttccaaccg
     3781 ccatgttaaa atcttctctg agaaagaatg ttataaaaaa taatcattct atcaccaaag
     3841 gagagaaaaa tgataactaa aaaacagaga aaactaaaaa gacacacaac aatcagacgc
     3901 ctgtgtcatc aagccctagc agctaccctc atcacaggaa gcctgatggg aacaggacta
     3961 cttggaaata aagtcgtgta tggggatatg aaaagcgatg ccaaaaaggt attagcaaca
     4021 ttgcaaaaag gtaatcataa acaagagtta aaaaaagttc ttagaactat tggtgatgat
     4081 agtttgctat tattatggtt acttgtatcg ggtgattcca atttagatga aagtaataaa
     4141 agttttgatt atttatcaat ttggaatact ggatctagag ttggtaaagt gatatctcct
     4201 actgaatact ttaaacaaga atcaaaaaac actgaaaata ggcaagctgt ttatagtgaa
     4261 tttaaacaac gcgtagaaga acgatctaaa aaagccaagg aagccactga agcactaaac
     4321 caaaaagctc aattggaggc tacagttaaa aatataaacg aagaacttga aaaaactaga
     4381 gaaggtttta aagttgtgag tgaaaactca aacaaattag aaaaacaatt aatggctgag
     4441 aaaataaaaa cacgtacagc tgaagaaact gccaaacaag ctaaaaccga taaagaaaaa
     4501 gcagaggctg aagctaaaaa agcgaaagag gaagctaaga ctgcggaagg aaaagttaaa
     4561 caagcagaaa ctgagaaaag gaatgcggaa gctaaggcta gaaccgctga agaagaagct
     4621 aaacaagcta cggctgataa agaaaaggca gagactgaag ctaaaaaagc gaaagaagaa
     4681 gctaagaccg ctaaagaagc tgctcatcaa gaacaagaaa aagctaaaca attagaacaa
     4741 gctaatcaac aggctaacca aagagctaat ctggcagaaa aatctaaaaa agatttagaa
     4801 actcaaaaag aaaaacttga acaagagatt aaagaagcta cagaagctaa aaacaaagcc
     4861 gagcaaaaat taaaagacct acaagattca gctagtcaag gcagtgaatt gtctaaacag
     4921 ctgttaaaag aaaaagaaga attaacaaca aaacttcaag agcttcaaaa acaagctgag
     4981 gaaaaaacaa ctgaaattga aaagctaaaa caagagcttg aagctaataa acaaaacagt
     5041 ggtcagctag gtcaacagga acaaaagctt caagagcaat tgaataaggt tcaaaaagag
     5101 ctgaaacaaa aggaaatgga gttaaaacaa gctcaagaac agctgaaaca agaacaaaaa
     5161 cctcacgaag gtggcggaga ttctgacgct tccaaagcaa gaatcactga gctagaaaaa
     5221 caagttcaaa cactaaccaa ggaaaaggca gatctgtcat caacccttga gtcaacaaaa
     5281 gctcaattgt cagagactca agcaagacta tcagaagctc aaaaacaatt gactgctgct
     5341 caagaaaagt taacaacact tgaagccgag aaaacagcgc ttcaacatca agttgagacc
     5401 atttcaaaac agctatcaga aacacgtgac cttagcgaaa aggaaaaagc agcactccaa
     5461 gagcaaatca ataagctaaa ggctgagatt gagcaaaaga ccaaggaaat tgaagcctta
     5521 aagcaaggca tgcaatcaca tcaaggtcaa gaaaaaccaa aggatccaaa aactccggaa
     5581 acaccaaagg atccaaagac tcctgagaaa aacgatcagc cacaagcgcc tgaaaaacgt
     5641 agtgtccctt ggactgctct tacaccagct aagccaattg acactaccaa agctcctaag
     5701 agctcagcac caagcccaca gactggggca gcaacaccta aaaaacaatt accagcaact
     5761 ggtgatacag cgacacctag cttctttacc gctgctgcta tggcagtatt ggctagcgtc
     5821 ggtgtcctaa atctctcacc tagacgcaaa aagaatcaaa acaaccgtta atgtagagac
     5881 tctcatatct ggattgaata acagcaaacc cgacatgagc aaaaacaaat gtctaaccaa
     5941 aaatcactga cattagtact ttaaccaaag cctttgagtc aagctaaaca ggctgtcctg
     6001 cctattggct tgactcgttt tgtgattgtg aaacacacca aggtcaaacc taccttgtcc
     6061 tccattttaa acctactctt ttctcccata cccactttag cttacgcaag aaggtgccta
     6121 atcatcactt ttggtagctt cgatgctcta tataaatgga tcaacaaaga taaatcatac
     6181 aaaactgcga gttgttccta tagtcacgat agctcttaca gatatgaaaa gtaaatacag
     6241 ctattaaaaa tatggtacaa taggggtacg atttttagga ggcatgtatg gtttcagttc
     6301 tttcacgagt gattaaggga ataattattg cgcttggctt tattttaccg ggagtatctg
     6361 gaggagtatt agccgctatc cttgggatct atgagcgtat cattgccttt ttagctcata
     6421 tacgtgagca ttttgttgag aatgttctct ttttcctgcc tgttggggtt ggtggtattt
     6481 tagggattgc cctcttttct taccctgttg actatctgct caagcactat caggtaccag
     6541 tcttatgggg cttcgctggg gccatcatag gaaccgtacc tagcctgata aagacttcga
     6601 caaaaacatc tcagcgtgac caagttgatt ggctctggct agtattaacc tttgtcctat
     6661 caggactggg actttatttc ttaaatgatc tcgttgggac aatacctgca agctttaccg
     6721 cctttgtcct agctggtgcc ttgattgctt taggtatttt ggtacctggt cttagcccgt
     6781 ctaatctttt attaatttta ggactttact cacccatgct gattggcttt aaatcacttg
     6841 atttggtagg aaccttttta cccattgcta ttggtggctt attaaccatg ctagcttttt
     6901 ccaagattat ggattttgct ctcaagcact accattcacg cgtttaccac tttattatcg
     6961 gtatcgtcct atccagcacc ctgcttattt taattccaaa tagcagtaat aaggaagcta
     7021 tctcttacgc cggtgcaggt cttggcacct ggctaatggc tctgctatta tttggccttg
     7081 gtgtctggct tggtctatgg atgagccagc ttgaggagaa atacaaataa cactcgatac
     7141 accagcaagt acctctaaca gcagcattaa gatcaaaaaa acgaatgact agctctcagc
     7201 cttatcacca gctgtgacta gcattcgttt ttttatatgt catcatgctg tcttgcctct
     7261 gtcacgattt ctataaaacg gttcgtcaat tgagcagtta taccccagat aggcttttct
     7321 aaatgctcat agagtaatac ctgatcttgc atgtacctca acctgtactg ctctccatta
     7381 gggatacgat ccaacggaaa gtctgacgag attatcgatt gcatttgtaa aggataagca
     7441 acaggagctt gcgccatgag ctcctccaaa ggcaccgtaa acaagctatc aacctcttca
     7501 ttgaccctaa gccttctcca atcatcaata gccagttccg caacaaagca atgaatgcta
     7561 cgagtcggct gaactaaata gtcaatctcc ccccaaacat gaacctgctc aggctctata
     7621 ttgagctcct ctaccgtctc acgaatagcc gcctgctgat aagtctcacc ctcctccacg
     7681 cgcccactag gaaaagaaac ctcccctggc ttgaatg
//
LOCUS       DARYMD010000074         7495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYMD010000074 DARYMD010000000
VERSION     DARYMD010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            436..975
                     /locus_tag="TU818_001799"
     CDS             436..975
                     /locus_tag="TU818_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924582.1"
                     /translation="MRQLIAAMVEKNQDLPRNILVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSRALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLTLDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGELVAKGELHV"
     gene            972..2087
                     /locus_tag="TU818_001800"
     CDS             972..2087
                     /locus_tag="TU818_001800"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL0924583.1"
                     /translation="MIDVYIQRGLRTPIGLAGKQFARVRPELLGAQLINALVKADKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGRYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            2077..3339
                     /locus_tag="TU818_001801"
     CDS             2077..3339
                     /locus_tag="TU818_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL0924584.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEQEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSNFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPRLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQGSLTAVKAYLEAHLSPAQRPKRYILLKEL
                     PLNDSGKLDSRRLSQLAHKSTKAAHNTK"
     gene            3385..4404
                     /locus_tag="TU818_001802"
     CDS             3385..4404
                     /locus_tag="TU818_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL0924585.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSTSQQLLAAASAIDA
                     RLGSPTFLAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEDMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGCFLNEIDGEVVTNKGIINGASFNYGTAGKRHWELDVAPISRHDPTFRKK
                     CLVGHQAPKWLKRSWLQLSPLDFDYSYFNAKGFFSLNSKSCFALVKRQARAFRWQIWR
                     SRFFK"
     gene            4603..5313
                     /locus_tag="TU818_001803"
     CDS             4603..5313
                     /locus_tag="TU818_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0924586.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            5306..6658
                     /gene="vicK"
                     /locus_tag="TU818_001804"
     CDS             5306..6658
                     /gene="vicK"
                     /locus_tag="TU818_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL0924587.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGAGLGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            6662..7471
                     /locus_tag="TU818_001805"
     CDS             6662..7471
                     /locus_tag="TU818_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL0924588.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     AQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
BASE COUNT         2018 a         1599 c         1799 g         2079 t
ORIGIN      
        1 cctcggcacg atagtcctga acccttgttt cagcctactt cttcactgtc ctaagatcgc
       61 ttttaggatg gccttgccaa gtctaggcct tagttggagt accgtaacat tcgcagcagc
      121 ctttatcagc taatgtctta gaatgataat aggtcatgcg acttatctag cgcgtgaatg
      181 accttgaagc ttgccttgtg tgctttcttc tgtctatttc aagtagagct gaatgactat
      241 cagttacctg taggcagagg ctgtagcagc cttgatttat taaatgatat tgaacatgat
      301 gtgatcagac aaaaaaggtt aggctaaagg ctcgcctttt tttgctaact aagccttgtt
      361 tttgctgttt tttcttttct tgtgttcagg tattcagtat aataaagtta acttgttcgc
      421 aaaaggatgg ttacaatgag acagctaatc gcagctatgg ttgagaaaaa tcaggattta
      481 ccaagaaaca tccttgtggc tgagatgagc ttggaaaaag ctgtgcagcc agatgattat
      541 cgcgtaaagg attatcgaaa tctgcggcag atcagattga ctacatcagg gcttgtgcta
      601 gaggttcgat tactaaaagg gctaccagcc aggtggctga aaaaggacac aagtgctaag
      661 ccttctaaag cagttaatag ccgagcatta gctgagcata gccatgtact gagcgttaat
      721 caggcggcct tacagcaatt tctagcagaa acaggagatc aaaatcctct tcatcaaaca
      781 gctccctata tcttaccggg agccctcttg atggaagagg ttagcagctg gcttacttta
      841 gattaccgta ggctaagcct gcgtttttat gccccagcgg ttgtgaatgc tcctattcac
      901 ctagtgatga gagaaaaagc tatcagcctc tatcaggcag gagaattagt cgcaaaagga
      961 gagcttcacg tatgattgat gtctacattc aaagagggct tagaacgcct attggtctag
     1021 ctggcaagca atttgctagg gtgcgtccag aactgcttgg tgctcagctg attaatgcct
     1081 tagtcaaagc agataagctg gctattgatg aggtgatctg cggtaatgct gttgggacag
     1141 gcggtaatat tggccggctg atgactctgt attctgactt gggagagacc gtacctgcca
     1201 taaccgttga catgcaatgt gcctcggctg gtgcagctct tactatgggc tatgctaaaa
     1261 tcaaggcagg tcttgccact agcttgttag caggagggat cgaaagcagc tctttgcagc
     1321 ctcagcgtat ctatgctgct gctgatagcc gatcaggtgc ttatcaggta gctcagtttt
     1381 caccagatac cagtagccag ctggctatga tagcaggagc agagcgggtg gctcaggcct
     1441 accaaatgac cccctcacag ctcaaccagt ggacccttac tagccaccag cgagcacaca
     1501 tagctaggca gaagcattgg ttagctgata ttatattagc aatgccagga atgtctgatc
     1561 aaggcattcg ccctcgcctg tcagaaaagg tcttgagcaa ggtgccgccg atacttgata
     1621 aggctggcct catcagtgct gctaatacct gcttgaccca tgacgcagca gcatttttag
     1681 tgctaagcaa tcaaagatca gcctatcaaa tccttgatct tgttgaggtt gctggcaatc
     1741 ctaaaaccag tcctcaaatg gtggttgagg ccagtcaggt cttattagct agaaacggcc
     1801 tagccatgac ggatatggat gcgatcgagt ggaatgaagc ttttgcagtg attgatctgc
     1861 tttttgagca ttattttgtg gaggcccttg atcgctacaa tatttttgga ggcgctcttg
     1921 cctacggtca tccctttggc gcgtcagcag ccattatcat tttgcatcta atgcaggctt
     1981 tggccttaaa gcaaggaagg tatggtttag cagccattcc agcagctggt ggtcaagcct
     2041 ttgccctgtt attggaatat cataaggact actcacatgc tatctagact gctagcttgg
     2101 gcaagccaag caccacaaag acctgctatc ctaacagacc aaaaaaccct aacctatcag
     2161 gatcttgtag agcagatctt ggcttatcag cctcaggagt ctatctccta tccgaccctg
     2221 attgtcaaaa gggattgctt ccagcagctg attgcttttt gctatcattt gcaacatgga
     2281 aactacccac ttatctgtca cccaaatcta ccagaacaag agcaaaggcg tctgtctagc
     2341 tgcgatcctc catcagacaa ggcggctttt gcggtgctta gctctggctc tactggccgt
     2401 cccaaggttt tttggcgctc ctgggcttct tggtctaatt tttttgagca gcaaaaccag
     2461 ctgttttatt tctcggagca aacaaggcta tttagccatg gaagcttgag ctttacaggc
     2521 aatttgaact tagctctggc gcagctctgg gccggaggct gtctggtctt tagtgatcag
     2581 cggtccttta agggctggtc ctctgtttgg cgcaggcaaa aggttactca tttatatctc
     2641 ttaccgagtc tgctacagcg gctactgcct tacttttctg ctgatagcta ttttgccccg
     2701 tatttattaa cctcatctca gcacttgtca ccagagctga ttcgcagcta ttaccaacgc
     2761 tttccgcggc ttgagttgtt gatgttttac ggtgccagtg agctttcctt tatcagctgg
     2821 tgtcagggct ttgaggctat ggcaatagct ggctttgtag ggcgtccctt tcctcaggta
     2881 aagctggagc tccgagaggg gcacattttt gttcagactc cctatgccat tgagggcatt
     2941 gagcagccct atagtgtcga tgatgtgggg gaaatgacag cagcaggctt gattctaaag
     3001 gggcgaacca aggactgggt gaatcagcaa ggtgtcaaat gccatcttcc tagccttgtt
     3061 cagctagtcc accagtcagg agttgttcaa gaagcagcag cgataaaggg tggcagcagt
     3121 gcagctgatg agcatgtgat cctgtgcttg gtgttgaaaa agcagggaag ccttaccgct
     3181 gttaaggcct atcttgaggc gcacctaagc ccagctcaga ggcctaaacg gtatatactc
     3241 ttaaaggagc taccacttaa tgacagtgga aagcttgata gcagaaggct tagccagctc
     3301 gcccacaaat caactaaagc tgctcataac accaaataag gaaaagtcac ctgagcccaa
     3361 agcatcagct caatatggta taatatggtc aaaaaaggag gtcagttgat gaagcaggat
     3421 atgttagcac gttatcaggc actcaagcct tacgtaagag caggtctttc ctcgacctct
     3481 cagcagctat tggcagctgc ctcagctatt gatgctcgct taggctcacc gaccttttta
     3541 gccatttggc agtgtgaaaa acagtgtcga tctcccaagg aattactagg gcttgttcta
     3601 gatcttgtcg gcatgccaat agagttatcc ggaaggctag aggatacgca ggctctgctg
     3661 agtcgctttt atcctgactt gccaccggat cattgctttt gggtggagct agcccagatg
     3721 gttagtcttg cttttccgga taaggagcta gcgcagcaga gcgcgttagc taagggtctt
     3781 catcagcttc gctatctcat ttcgagccag caggcacaat atattcgcag ccattttaga
     3841 tcagaggaca tgactgacgc tcaggcactg gctatctttc tcaaggataa aaaaggccca
     3901 gctttttggc gcagccagcc tgactacacg cttatggaat cggctcgtct gcataacaag
     3961 ctaaagcttg tcaatggatt agcaagcttt cctgatcatg agatttccca taatattaaa
     4021 attctgttgc atttccatac cgaatttatc ctcgatagtc aggggtgttt tcttaatgaa
     4081 atagatggtg aagtggtgac caacaaggga atcattaacg gagcctcctt caattatggc
     4141 acagcaggca agaggcattg ggagctagat gttgctccta tcagccgaca tgacccgacc
     4201 tttaggaaaa aatgcttagt aggccaccaa gctcctaagt ggctgaagcg ctcttggctt
     4261 cagttatcgc cactagattt tgactattct tattttaatg ctaagggctt ttttagcctc
     4321 aatagcaaaa gctgctttgc cttggttaag cgacaggcac gtgcctttag atggcagatc
     4381 tggcgtagca gattttttaa gtaatggatc agtagctggc ttgcttgatg aggtatttag
     4441 agagcgtttt tgtggctagt atagtggtca ttgtcaattt ctcctaaatt ttgatataat
     4501 caaaaggaca taataaaatg atcggtctcg tctctaaatc cttatggaat agggattagg
     4561 cagcgtagca attaatgaag agaaatgttc tgaggtataa gcatgaagaa aatactgatt
     4621 gttgatgatg aaaagccgat ttctgatatc attaaattta atctgacaaa ggaaggctat
     4681 gatacggtca cagcatttga tggcaaagag gccgttgcag tctttgaaga ggaaaagcca
     4741 gatttgatta ttttggattt gatgcttcct gaattagatg gccttgaggt agccaaggaa
     4801 atccgcaaga ccagccatat tcctatcatc atgctatctg ctaaggatag cgaatttgat
     4861 aaggtgattg gacttgaaat aggggccgat gattatgtga ctaagccctt ttcaaatcgt
     4921 gagctgctgg cgcgtgtcaa ggcacatttg cgtcggacag agactattga gacagcagta
     4981 gccgaagaaa atgcctcctc aggctctcag gagctaacca tcggcaatct acagatttta
     5041 ccagatgcct ttatcgctaa aaagcatggt caagaggttg agctgaccca tcgtgagttt
     5101 gaattgctgc atcatctggc aaaccatatc ggacaggtca tgacacgtga gcatttgctt
     5161 gagaccgtat ggggctacga ttattttggc gatgttcgaa ccgttgacgt tactatccgt
     5221 cgcctgcgcg aaaaaataga ggatacaccg agtcgtccag agtatatttt gacaagacgt
     5281 ggtgttgggt actacatgaa ggcttatgac taaggacatc attggaaacc tttctgcatt
     5341 tgagctagcc atactcttat tgcttgtttt tgttgctttt tatttcattc atttagccat
     5401 tcgtgattat cgcaatgctc ggatcattcg tctgatgagc cataagataa gagatttgat
     5461 caatggtcgc tatactgata cgatcaatga aaaggctgat attgaattga tggagctgtc
     5521 tgagcagctc aacgacctat cagatgtttt tcgtctgacc catgaaaacc ttgcccaaga
     5581 gaaaaatcgt cttgctagta ttttggctta tatgacagat ggggtccttg cgaccaatcg
     5641 ttccggcaag attatcatga ttaatgagac tgctcaaaag cagctcaatt taaatcgtga
     5701 gcaggcgctg gaaaaaaaca ttacagattt attagacagt gactcacctt acacctaccg
     5761 agagctggtc tcaaaaacac cgattgtgac cttaaatcgt cgtaatgaca caggagagtt
     5821 tgtttcgctg cggctgcgtt ttgcgcttaa taggcgagag agcggcttta tttcaggtct
     5881 agttgttgtg cttcatgaca cgactgagca ggaaaaggag gagcgtgagc gcagactctt
     5941 tgtctcaaat gttagccatg agcttcgcac acctttgacc tctgtcaagt catacctaga
     6001 ggctctagat gagggcgcgc taaaggagga catagcccca agctttataa aggtctcact
     6061 agacgaaacc aatcgcatga tgcgcatgat ttcagatttg ctcaatctat caagaattga
     6121 taatcatgtg acacagctgt ctgttgaaat gaccaacttt acagccttta tgacctctat
     6181 cttaaaccgc tttgatttgg tgaaaaatca gcacaccagt actggaaaat cctatgaaat
     6241 tgtcagagat taccctatca cctctatttg gctagaaatt gataacgata aaatgacgca
     6301 ggtcattgaa aatattttaa acaatgccat caaatattca cctgatggtg ggaaaattat
     6361 cgtaaacatg aaaacaacag atacccagct aatcatttcg atttctgatg agggattggg
     6421 cataccaaag aaggacctgc ctttgatttt tgaccgtttt taccgagtgg ataaggctag
     6481 aagtcgggcg cagggggggg ccggcttagg gctggctatt gctaaagaaa ttattaagca
     6541 gcgccgcggc tttatctggg ctaagagtga ctatggcaag gggtcaacct ttaccattgt
     6601 gttaccttac gaaaaggatg ctgctatcta tgatgaatgg gaggatgata ttgattaatt
     6661 gatgagtgag gttggcttta aatatagtat tttagcatca ggatcgacag gtaactgctt
     6721 ttacttggaa acgcccaaga agcgactgtt gattgatgca ggactgactg gaaagaaaat
     6781 caccagtctt cttgctgaga ttgacagaag gcctgaggat ttggatgcta tcttgattac
     6841 ccacgagcat tccgaccata tcaagggtgt tggaatcatg gctcgaaaat ataacctaga
     6901 tgtctatgcc aatgaaaaga cttggcagat gattgatgag cgtcatatga ttggcaacct
     6961 agacgtcgca caaaagcatg tctttgaaag aggtaagacc atgacctttg gagacattga
     7021 cattgagagc tttggtgtta gtcatgacgc tgtagaccca cagttttacc gcattatgaa
     7081 ggataacaag tcctttgtca tgctgacgga tacaggatat gtgagcgacc gcttggctgg
     7141 gatcattgaa aatgctgacg gctacttgat tgagtcaaat cacgatgtgg agatattgcg
     7201 agccggctct tatccttgga gcctcaagca gcgaatctta tctgacctag ggcatttatc
     7261 caatgaagat ggtgctggcg ctatgattcg aagcttgggc aataaaacaa agaaaatcta
     7321 cctcggtcac ctaagccagg agaacaatat caaagaatta gcacacatga caatggtcaa
     7381 tcagctagca atggcagatt taggtgttgg aacagatttt actgttcatg acacctcacc
     7441 agataccgcc tgtcccttga cagacatcta gccttatgac ttcacccctg cttgt
//
LOCUS       DARYMD010000075         7238 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYMD010000075 DARYMD010000000
VERSION     DARYMD010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7238
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            21..623
                     /locus_tag="TU818_001806"
     CDS             21..623
                     /locus_tag="TU818_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924589.1"
                     /translation="MISVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAIKNNT
                     DDADGMYFVQSYEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPEEETL
                     FRSAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIKYGLG
                     KMIAEIPVDYMLNLLSPGYHIARYIDSIDTVPNNNRINLW"
     gene            complement(1039..1419)
                     /locus_tag="TU818_001807"
     CDS             complement(1039..1419)
                     /locus_tag="TU818_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL0924590.1"
                     /translation="MIKVFETRVTAIGSEAADMISAANMLILFDQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFAWLRCS"
     gene            complement(1453..2445)
                     /locus_tag="TU818_001808"
     CDS             complement(1453..2445)
                     /locus_tag="TU818_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL0924591.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSVPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(2461..3006)
                     /locus_tag="TU818_001809"
     CDS             complement(2461..3006)
                     /locus_tag="TU818_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL0924592.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYPLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKMIEL"
     gene            complement(3142..3603)
                     /locus_tag="TU818_001810"
     CDS             complement(3142..3603)
                     /locus_tag="TU818_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL0924593.1"
                     /translation="MSFMVIFGLFVIVAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            complement(3603..5375)
                     /locus_tag="TU818_001811"
     CDS             complement(3603..5375)
                     /locus_tag="TU818_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL0924594.1"
                     /translation="MSNAASSIGQLNDILDGDATITQQGAFLQLQVYDYARLETILAG
                     SLRKASDFNSASKRVAYLLKRLLQSSSALVIDDLADEIGVSRSTINKDLKAAKALART
                     YSVMIQGKPNHGIQAVGTELNLRLLYVHEVYKYFEPQGLCGDSLFFLDELYQTYQLPR
                     KIQELLTKSFAITIERMRQGRYLTDPIPYYSNEVDSSAFMEELVYHIELAYQLSLSQY
                     ERQFISFPLNIQYIEDLAYQEKPLQQSIVRLYSKMIEHIKTSLLVTIDQDKLFVALHT
                     HLKLLVNRLIFHVQANDIFHGEIRYKYPLAFDMAIVAAQVLAEEFDCAIELSECSYLA
                     LYFEMMMKDAEHVTEPTVKKIAVVCTTGRGTANMICRRLSKVLGPDLLISQFSEEQFN
                     PDDNDHYFAIFTTVPLKFGQLKSPVLQITNLFDDQWLQNEWRRVHHYHQKNLATITLH
                     FARLSKGKAYTDYLTEMAELLEEKQLVDRQFGQRLLEREALQSTLFGNRIAFPHTIND
                     KETKTVLLLGLLDEPYREHDCLVEFIFLVAISKRVEAQMEADLLKIYDDIFKIASDDK
                     LQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(5669..7018)
                     /locus_tag="TU818_001812"
     CDS             complement(5669..7018)
                     /locus_tag="TU818_001812"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL0924595.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
BASE COUNT         2138 a         1646 c         1451 g         2003 t
ORIGIN      
        1 gaagggcatg gtgaatcaat atgatttctg taaagaaaaa tttatgtcgc ttaggtgttt
       61 tgtctagtag tttattactt ttaacagctg caacgactcc atctgtcatt gcttttgcgg
      121 atattcaaac aagtgccata aaaaataata cagatgacgc agatggtatg tattttgttc
      181 aaagttatga aatgtctgta gaagataaag aattgcttgt tcgaaatgtt aaagcaaatc
      241 atcctacagt ttctgaagat tttatcagag aagttattga aagacaatta gtaggtgatt
      301 atacattacc tgaagaagag actcttttcc gctcagcatg gcaaggggtt acagtagatc
      361 aattgggagc agctctagat gtggctattg gtatggcatt aacaggtgga gctggatcaa
      421 ttgctgctgg tgttttgaga gtcggaaaaa gagaagctgt tggtcgggta aaatcaattc
      481 taattaaata tgggctaggt aaaatgatag ctgaaattcc agtcgattac atgttaaatt
      541 tattatcgcc aggatatcat atagctagat atattgatag tattgataca gttcctaata
      601 ataatagaat taacctttgg taagttagga aatttagtac tgtgaaaaaa atttatattt
      661 tatattttgt gctttattgc ttattatacc ttgtcatatc attattaatt agctatggta
      721 tgtcccattt tcttaacatg gaatttaaat ggtggaataa attagctata tctctaacat
      781 ctttatatat tatttatcaa atgctgaaaa aggataaatt aattaaataa tcaactaatg
      841 tacaagttgt ctttaagctg aaaagaggct atcaacagcc tctttttttg atgatataga
      901 taagcccaat gcttccttag aagagctctt ctgtgagatg accttatcac ctgacattag
      961 ctgcttggct catgcctaca gctaaaggaa atgccctgca aggatagcag cacttagcct
     1021 gctggtctac ggcgtgtctc agctgcacct aagccaagca aagatttgta ctaggctgcc
     1081 ctgcctgacc tgtggcagcc ctttgccctt gacatgcaga gtaccgggaa gagagctggc
     1141 tgtggagcca tcaaaagaaa tggttatatg ccctagctga gcaagatttt tttcaacaac
     1201 agcacctact gctgtgatgt catatgccat ttgatcaatg actagctgac caccagcaga
     1261 gatagaccca gacacttgct tgttgtcaat cgtatagcaa aagtctgcca agtctgccgg
     1321 tgctccctga tcaaaaagaa taagcatatt ggcagcacta atcatgtctg ccgcctccga
     1381 tccaatagcg gtaactcttg tttcaaatac ttttatcata cattctctct cttcctatca
     1441 tacgatagct ccttactgat acaaaccaat acttgcaatc caagcaacaa caacccgagg
     1501 aacaccattt aaaaagcgtg aataaagcac agatggcacc ccaacctcta ctgtctcagc
     1561 attagcctct gataaaccaa gcgctactgg aatgaaatca cagccatttt gcgtattaat
     1621 agcaaaaagt gcaggaagag ccatttgtgg tggaatagtg ccttttccaa tctcaacacc
     1681 aatgagcgtt ccgatgattt gactaataac cgcaccaggt cctaacagcg gtgataaaaa
     1741 tggcaacgaa cagataaagc caatgataat caagccccaa atattaccag ccagcggtac
     1801 catgagcttg gctagccaat taccaacacc agagccttgg ataaaaccaa ttaaaagaga
     1861 gacaaatgcc atgaatggca aaatcgtatt gattaaggtc tggatagcct cacgcgccgc
     1921 ttggttgaag atagcaacta ccttacctgc tcccatacca atgcgggcaa caaagctgct
     1981 ttctgcgcgc tgctcagtaa tctttttgct agtatcatag ctgctagcct ttggaactga
     2041 tgactcctta gcactagcaa catgagcctg agcgtcactg gctgtgattt gctcaagacc
     2101 tacagcagac acgtaaatgt cctcggtaat gtactgtgcc aagggaccgc ttttacctgt
     2161 cgccacgata ttaatggttg gaatgccttt tttagggtaa ataccgcagc gtagggtgcc
     2221 gccacaatcc acaatagcta gggctatctc atcatcaggg attgaggtca caaagccatt
     2281 gaccgcctcc atacctgtta gggcagcaat tttatcgaca atgtcaggct tttttccacc
     2341 gccagtaata tagataaatt tgtgcttagc ttctgttggt gtaatggtta gcggcccacc
     2401 atagccaccg ctccccttaa caactgtaat actgtgataa gtcatcatgc tacctctctt
     2461 ctataattca atcatcttac ttaatgtcac accctgctgc ttggccacgt aggctgtcgt
     2521 aaagtcagtt acccagccac caacaaagtt catgattaac ccaaccaagg ggtaacgaat
     2581 cgccaagtcc atttggctca agcctagcgt cttgatacct gaggcaatac ctaaccagac
     2641 aaacaattct cccggattaa tgtgtggaaa gacaccgttt gacgtatgac aaaattgcat
     2701 ttgagcggca acatagcttg gcttgtaata ctcgggcata aagcgtccca tgctgattgc
     2761 catcggatta cccagcataa aagctgaaat aaaaggcaat accatgtagc gactgatagg
     2821 gtttttagca gagatttttg ccaattgatt gaccctttga tctcctaaaa taccaattaa
     2881 ggcattcatt gcaaccagca gcatcaagac caccggcaca atgccagtca tccagctgac
     2941 aaaggtttca ccaccaagct ggaagagctt cataaagcct tccgcaaatc ttgttatcat
     3001 ttccataaat aaactcctca tatgatgtac ttacaagcaa gacaatacaa atgtactgcc
     3061 tgcttgataa tagctgcttg agctggactc aaaacagctt ttatgttgac aaggcaagca
     3121 atcaatcctg cttttggcac cttacttgaa gcgtgccagc agctgcttgg cctgtagggt
     3181 ccaatcaaag gctgaggcat attttggtgc gtcctcatag acccctgcct caaccctcaa
     3241 gaagacctct cttgcgtcct caatagccaa gcgcagcaat ttattttctc gtctaatcaa
     3301 gggattgtag cgatcaaaat aatgaatatc ctgaccgata taagctggca ttggcttaaa
     3361 cctggctgcc actgtcacac cctgcatttg cctagcatct aataccttac ctgactgatc
     3421 caaggcaaac atgacaatgg ttccggccct gattttcccg gctctacggc caatagcaac
     3481 gcgcccctgt cgtctaagac tggcataaac agcattgaag tgcttaagct gtctcagacc
     3541 tagcaataat tgaaaaaggt aagcaactat gacaaatagt ccaaaaataa ccataaaact
     3601 cattaaaaaa ctcctttttc cttggtaaat gcaataaact cagcttgact ttttaggctc
     3661 cttagctccg cctgaagctt atcatcgctt gctattttga aaatatcatc ataaattttc
     3721 aagagatcag cctccatctg cgcttcaacc ctcttggaaa tagccactag aaaaataaac
     3781 tccaccagac agtcatgctc acgataaggc tcgtctaata gacccagcag caggacagtc
     3841 tttgtttcct tgtcattaat cgtatgtgga aaggcaatgc gattgccaaa taaggttgat
     3901 tgcagggcct cacgctctag caggcgttga ccaaactgcc tgtcaaccag ctgcttttcc
     3961 tcaagcagct ccgccatttc agtcaggtag tcagtgtagg ccttcccctt tgacagacga
     4021 gcaaagtgta gggtgatggt cgccaggttt ttctggtgat aatgatgtac cctgcgccat
     4081 tcattttgca gccactggtc atcaaacaga tttgtgattt ggagaacagg agattttagc
     4141 tgaccaaact tcagcggcac agtggtgaat atggcaaaat agtgatcatt gtcatcagga
     4201 ttgaattgct cctcagagaa ttgtgagatc aacaaatcag gacctagcac cttgctcaag
     4261 cgacgacaaa tcatattggc agtgccacga cctgtcgtgc agacaacggc aatttttttc
     4321 actgttggct ctgtcacatg ctcagcgtct ttcatcatca tttcgaaata aagggccaaa
     4381 tagctacact cagacaattc tatggcgcag tcaaactcct ctgctaagac ctgagctgcg
     4441 acaatggcca tatcaaaggc caaggggtat ttgtatctaa tttctccatg aaaaatatca
     4501 ttggcctgaa catgaaaaat caaacgattc accaagagct tcaaatgcgt atgcaaagca
     4561 acaaaaagct tgtcttggtc aatagtcacc aagagactgg tcttgatgtg ctcaatcatt
     4621 tttgaataaa gcctgacaat gctctgttgc agaggctttt cttgataggc tagatcctcg
     4681 atgtattgga tattcaaggg aaagctaata aactggcgct cgtattgact cagtgacagc
     4741 tgataggcta gctcaatgtg atagaccagc tcctccataa aggcactgga atcaacctca
     4801 ttgctatagt aaggaatagg atctgtcaga tacctgccct gacgcattcg ctcaatggtt
     4861 atcgcaaagc tcttggtcaa aagctcttgg attttgcgag gaagctggta ggtctgatac
     4921 agctcatcta gaaaaaacaa gctatcacca cacaagccct gcggctcaaa gtatttgtaa
     4981 acctcatgaa cataaagcag ccgaaggttc aactcagtgc caacagcctg tatgccatga
     5041 ttgggcttgc cctgaatcat gaccgaatag gtcctagcaa gagccttggc tgcctttagg
     5101 tctttattga tcgtgctgcg actgacgcca atctcatcag ccaaatcatc aatgactaaa
     5161 gctgaggagc tttgcagtag cctttttaga agataagcta cccgcttgct agcggaatta
     5221 aagtcactag ccttacgtaa actaccagct aatatcgtct ctaatctagc ataatcatag
     5281 acctgcagct gcaaaaaggc gccttgttgg gtgatggtcg catctccatc taaaatgtca
     5341 ttgagctgac caatgctact tgcagcgttt gacatcgtct tttcacaaag tcacagctta
     5401 gaaagctagc agaggagaca aaagcaagac cttatcagct aacagcagca tattaaacga
     5461 acagctagtg atactgatcc tactaagcat agagctccaa aagcctggct taaatagtat
     5521 tcaaaataga acaagagctc tcaagaacaa taacctagcg cactacttgc cttgataagc
     5581 ctaaccgacc ttgaaaagaa gcaaaaaaaa gagcctctca cgagactctt tgttatgttt
     5641 tagcagacta gtctagctag ctctgtcatt acaagcgtgc gttgagcgct gctcctagct
     5701 cttcaaagcc tggcttacca agaagggcaa acatgttttt cttgtaagcc tcaacacctg
     5761 gctgatcaaa tggatttacc ccattgaggt agcctgaaag ggcaatagca agctcaaaga
     5821 agtagatcgt atagcctagt gtaaattcgt cttgctctgg aagcgtgata aacatatttg
     5881 gcacaccacc gtctgtatgg gcaagaagga caccatctgt tgcttttttg ttgacaaagt
     5941 caacgtcttt gccttgtagg tagccaaggc catcaagatc ctcagccatt tctgggataa
     6001 tcacattttg acgtggctta tccacacgaa tcactgtctc aaagaggtta cggtagcctt
     6061 cttggataaa ttgaccaaga gaatgcaggt ctgtcgagaa attagctgaa gttgggtaaa
     6121 tacccttttg gtcctttcct tcagactcac cagccagttg cttccaccat tcgctaaaat
     6181 actgcaatga tggctcatag tttgccaaaa tttcagttac atagcctttg cgatagagga
     6241 tattgcgaac tacagcatat tggtaagcga tgttttctga gattttatct gatgacaggt
     6301 ccttacgagc tgcatttgcc ccctccatca gcgcggtaat atcagcaccc gatgctgcaa
     6361 ttggcaacaa gcccacagct gtcagcactg aaaaacgacc accaacatta tctggcacaa
     6421 caaaggtttc ccaatgattt gcatcagcct caaccttaac agcacccttg accttatcag
     6481 tcgttgcata gatacgcttg ttggcctctt cttgaccgta ctttttaaca agtaattctt
     6541 taaagacacg aaaggcgatt gcaggctctg ttgttgtacc agacttagaa atcacgttaa
     6601 cagagaaatc tttatcttga acatagtcca caagatcagc aagatagctt gatgagatgg
     6661 agttcccagc ataaagaatt tgtggtgctt tgcgctcttt tgctgtttgt aggttggcaa
     6721 aatggctgtt caaaaagtca atcgcagcct tagcaccaag gtaagagcca ccaataccaa
     6781 tcacaacaag aacgtcactg tcagccttaa tcttctcagc tgctttaagg atacgagcaa
     6841 attcttcttt gtcatagttt tcaggtaact caagccagcc caagaaatct gatccaggtc
     6901 cagtgccctg acgtagtgcc tgatcagcct ctgttacctg accttgtaaa aagtcaattt
     6961 catgctgtcc ggcaaattgc tcaagaacct ttgaataatc aaatgtaata tgtgacatta
     7021 ttttactccc ttaactttta aagtttcatt agtatcataa ccttttctat tcaatatttc
     7081 aatgtttttt atttttgggg agggtggcct gactttaacg acatgaggat catttctgtc
     7141 taaaagcagc tttgtgatga gcctagcgct tccctatctg cttctactat agcttactgg
     7201 ggctgatccg ggtgatgtgg tagcctcttg gcatagcc
//
LOCUS       DARYMD010000076         6885 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYMD010000076 DARYMD010000000
VERSION     DARYMD010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6885
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(25..486)
                     /locus_tag="TU818_001813"
     CDS             complement(25..486)
                     /locus_tag="TU818_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL0924596.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVAYVQHDVPQIILGGAVEP"
     gene            complement(530..1606)
                     /locus_tag="TU818_001814"
     CDS             complement(530..1606)
                     /locus_tag="TU818_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL0924597.1"
                     /translation="MSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFSQSLQAAFSEVTLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKAGAGMTYREFDAIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TU818_001815"
     CDS             complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TU818_001815"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL0924598.1"
                     /translation="MQDKLIIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETNSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEYGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLEKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKPGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVATGTPEEVAAVEESYTGQYLKLKL"
     gene            4915..5859
                     /locus_tag="TU818_001816"
     CDS             4915..5859
                     /locus_tag="TU818_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL0924599.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            6118..6768
                     /locus_tag="TU818_001817"
     CDS             6118..6768
                     /locus_tag="TU818_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HEL0924600.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNTTVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYSATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMAPQR"
BASE COUNT         1997 a         1792 c         1335 g         1761 t
ORIGIN      
        1 ttatgaccat tatcagcctt cggcctaagg ctcaacagcg ccacccaaga taatctgagg
       61 cacatcatgc tgaacataag caaccccttt tttatccatt agctcaatgg caaaagggtg
      121 gggacgataa tgggatttat aggtgatctt gcaaataccg gcctgaagga gggccttagt
      181 gcaattgata caaggaaagt gcgtgacata aatctctgtt ccagcagttg aaatgccctc
      241 cttagcacat tgaatcaaag cattcatctc tgcatgaaca gttctgatac aatgcccttc
      301 ttccatataa tgaccggctt cattacagtt atcagtcgcc gacacgccac cgttatagcc
      361 tgtcgcaata atgcgattgt ccttgaccaa gactgcaccg acaaatgctc gatcgcaggt
      421 tgatcgctta gatatcagct ctgcatttgc cataaaataa tcttgccatg atagcctatc
      481 tgtcatgctt tgtctcctaa tcccttctaa ctcacagcag ctaacaagcc tacgttaaaa
      541 caatcaattc ctttggtgcc ttggttaaga cctgacagcc tgtttctgtg atgacaagat
      601 cgtcctcaat acgcacaccg tatttgccgt ctaaatagat acccggttca tctgtcacca
      661 ccataccagc tagaagcctt tgatctgtct tagcaaaaaa tggatcctca tgaatatcaa
      721 gtccgatccc atgaccaatg ccatgtgtaa agtgactgcc atatcctgcc tcagtaatga
      781 gctgacgagg aatagcatca aactcacgat aggtcatgcc tgcaccagcc tttgcaatca
      841 aagcctgatt agctgcaaga accagctcat aaatctcacg ctcctggtct gtcacctgtc
      901 cgatatgaat agtccttgtc atatcactca cataatgctg ataataacag ccaaagtcaa
      961 gcgtcaaagt ctctccctgc tgaatgattt tatctgtagc acgaccatga ggcatggcag
     1021 aacgatagcc tgaggctgca atggtgtcaa aggaaatgcc tgaggcaccg tattgacgca
     1081 tgcgaaaatc caagaaatta gccacttcaa gctcacttgt ctgccccggc ttaataaagt
     1141 ccaagacatc acagaaggcc ttgtctgaaa tcgagcaggc tttagcaata atgtcaatct
     1201 cagaagcgtc cttaatcaga cgaagcgctt caataaagcc tgattgcggc agcaaagtca
     1261 cctctgaaaa ggctgcctga aggctttgag aaaaggaaaa ggacacctga tcctcaaagg
     1321 ctagactgct aagcttgtcc gcctgtagga ttgcagcaat ttcagccagc ggtgtgcggc
     1381 tctcaatgat atcaaagccc tcaatactag ccttagcaat taaggtataa cgcgaatctg
     1441 taataaaaac acgccgcttt ggactgataa agaccgtagc tgaggtccct gaaaagcctg
     1501 tcaggtaata aatattagtc agattagtaa ttaaaatagc ctccaagcct tttttttcca
     1561 gtaatgcttg gcaattgctt aagcgctgtg ctaaaaatga tgacatggta atctccttta
     1621 tcgacaaaac taccttaagt ttaccatgat ttcaacgctt ttaaaagcaa gacccattaa
     1681 agacagccaa caaaaaaagc atttctgaca gtggaccaaa aggctaatca gcttagccgc
     1741 cactaccaaa aatacccttt aaatatcacc cacgcccccc gcgaagagag ctactggcta
     1801 tctattattt aaattaaaat cacccctcat ttcaatccat gccctatcat cgttcatacg
     1861 aagatcactc tgtcaattga tgtcaggcct gcaactttac aatttcagct tcaggtactg
     1921 ccctgtgtag ctttcctcaa cagcggcaac ctcttcagga gtcccagttg caaccagttg
     1981 acctccacca acaccgcctt ctggaccaag gtcaataata tggtctgccg acttgatgac
     2041 atctaaattg tgctcaatca ctaaaacagt attgccatca tcaacaaagc gctctaaaac
     2101 cttcagtaat cgcgcaatgt catctgtatg cagccccgtc gttggctcat ctaaaatata
     2161 caagctttta ccagttgaac gcttgtgcaa ttcactagcc agcttcatgc gctgggcctc
     2221 gccacctgat agggttgtcg ctggctgccc tagagtaaca tagccaagcc caacgtcctt
     2281 aatggtctga attttacgag caatctttgg aatagctgag aaaaatacca gagcatcatc
     2341 taccgtcata tccaagattt cagcaatgtt tttgccctta taatggacct ccaacgtctc
     2401 tgaattatag cgtctgccat gacaaacatc acatggaacg taaacatctg gtaaaaaatg
     2461 catctcaatc ttgataatcc catctccaga gcaggcttca cagcggcctc ccttcacatt
     2521 aaaggagaag cgcccttttt tgtagccacg aatcttggct tcattagtct gggcaaagag
     2581 ctctcgaata tcatcaaaaa caccggtata ggtggcagga ttagagcgcg gtgtccgccc
     2641 aattgggctt tgatcaatat caatcaaccg ttccaaatgg tcaatgccag tgatagacct
     2701 atgcttgcct ggcttttcag agttacggtt tagcctttga gccactgctt ttttgagaat
     2761 gctattaacc agcgttgatt ttcctgagcc agagacccca gtcactgcaa taaatttctc
     2821 cagaggaaac ctcacatcaa gattctgcag attgttttgg gctgctccct tgatatcaat
     2881 atagcgacca ttgccagcac gtcgctccaa aggaacgggt attgatttgc gtccagacag
     2941 gtattgacca gtgatagacc ttttatgccg agcaacctgc tgaggcgttc cagaggcaac
     3001 aatctgcccg ccaaagtccc cagcaccagg tcccacatca atcagccaat ctgcctgcat
     3061 catggtatcc tcatcgtgct caaccacaat caaggtattt cccaagtcac gcattttttt
     3121 caagctatca atcaagcgat cgttatctcg ctggtgcaga ccaatagaag gctcgtccaa
     3181 aacgtaaagg acacctgaca gattagagcc aatttgcgtt gccaaacgga tacgctgact
     3241 ctctccacca gacaaggtgc ctgccgagcg agacaaggtc agataattca gaccgacatt
     3301 attcaaaaag gtcagccgat catgaatttc cttgataatt ggctttgcaa tggtgctttc
     3361 attgtctgac agctcaagcc gatctagcag ctgcagatgg tctgcaatag atagctctga
     3421 cacctgaccg atcgtcaagc catactcacc accaacacgc acacacaggg cttgatcatt
     3481 gaggcgatag ccatgacagc tcgcacaggt caattcgttc atatagcctc gcatgacatt
     3541 gcgggtatag tcactgttag tctcatggta gcgacggtta atatttgtca caaccccttc
     3601 aaagggaata tcaatgctgc gctcgccacc aaaatcattg acatagtgaa aatggaactc
     3661 ctgatcacct gagccataca ggatcagctc cttttcctgc tcgctcaatt gctcaaaagg
     3721 cttgtccata tcaacaccaa agctctgcat tgcctgctca agcatggttg ggtaataatt
     3781 tgacgagata ggattccaag gagcaagagc cccctctctc aaggtcttgc tgggatcagg
     3841 aacaactaga tccaaatcca cctccagctt gatccctaag ccatcacagg tagggcaaga
     3901 gccaaagggc gcgttaaatg aaaaaagacg aggctctagc tctggcactg taaaaccaca
     3961 taccggacag gaataatact ctgaaaacag caactcattg ccgtccatcg tatcaatcat
     4021 cagatagcca tctcccaagc gaagcgcagc ctctatcgaa tcaaaaagac gactgcggat
     4081 cccgtcctta ttgaccaagc gatcaatgac gacctctata ttgtgcattt tgcttttgga
     4141 taatgctggt acctctgaca catcaaaaat ctctccatca acacgcacgc gcacataacc
     4201 gtccttttga attttctcaa acactgtctt gtgctgaccc tttttacgac ggacaagagg
     4261 cgccaaaatc tgcatacgcg tccgctcagg caactctagc acctgctcaa caatctgctc
     4321 caccgaggaa gccgtaatag ccccatgccc attgatacaa tagggagtcc ccacacgcgc
     4381 ataaagaagc ctgaggtaat cattgatttc tgtcaccgta ccaacggttg atctaggatt
     4441 cttgctggtt gttttttggt caatagaaat agcaggacta agcccgtcta tagaatccac
     4501 atcaggcttt tccatgttgc ctaaaaattg cctagcatag gctgacaggc tctccacata
     4561 gcgacgttgt ccctcagcat agatggtatc aaaggcaagg ctagattttc cagatcctga
     4621 taagccggtc accacaacga gcttatcacg tggaatctcc acatcaatat tttttaaatt
     4681 gtgggcacgc gccccacgaa taatcaattt atcttgcatg ctcttgtgcc cccaggcacc
     4741 ctcctcatcg agatttattc cattataaca aaaatttcta ataatcagtt gccccaaaca
     4801 ccatgaattt gtagtataat agacaggtat tgagtgtttt tcaaaaaggc ttcgtctacc
     4861 tgatgacaag aagctcactt caatactgac taatcacaaa aaggagggct tgtcatgaaa
     4921 caaatgtttc tttcatcggc aattgaattc aaagaaatcg aaacattcga gccaggtgct
     4981 tggatcaaat tggtcaaccc ctcccaggaa gagtctatcg ccattgccga tcaatttaac
     5041 attgatattt ctgacctgcg tgcccctttg gacgttgaag aaacctcacg tattgctgtt
     5101 gaggacgact acaccttgat tatcgtcgac gttccggtct atgaggagcg caacaacaaa
     5161 agctactatg tgaccatgcc tttgggaatt atcgtcactg aaagcgcggt aatcaccacc
     5221 tgcctgcatg acatgacact ttttgatcag tttcataagc gtaaggttaa aaacttttac
     5281 acctttatga agacacgttt tgtctttcaa attctctacc gcaatgccga gcttttccta
     5341 accgcactaa gaacaattga ccgacaaagc gaacgcttgg aggctcagct tgaggcagca
     5401 acccgaaacg aagaattaat cgacatgatg gagcttgaaa aatccatcgt ctacctaaag
     5461 gcctccctaa agttcaacga gcgcattgtc aaaaaattat ccagctcaac cagctcactc
     5521 aaaaaatata ttgaggacga ggacctgctt gaggatacac tgattgagac ccaacaggct
     5581 attgagatgg ctggcattta tgaaaatgtc ttaaatgcca tgaccgaaac aaccgcctca
     5641 atcattaaca acaatcagaa caccatcatg aaaacattgg ctctgatgac gatggctcta
     5701 gatattccga cagtgatctt ctcagcctac ggcatgaact ttcaggataa ttggctgccg
     5761 ctcaatggcc ttagccatgc cttctggtat attgtcctgc tggcaaccct gctcagcagc
     5821 tttgttgtta tttattttat tagaaaaaaa tggttttaat aaccccattt ccaactgaaa
     5881 aagctactcc tgagctctac ctgtagacag ctcatcagct aaagcaggca ctactactgc
     5941 taaagcaaac aatcgtccca gcaagtaacg gtagctacta ctgcttgatc gtatgatcaa
     6001 gcgcaacata tcagctgcca tactagctgg caaagcaagc cagcaaggcg cccttgaggc
     6061 attatcccag gctagccctg cttacaatca tcacatcata taggagaatc ccctgtcatg
     6121 gacttacaac agcttaccaa aaaaaatcaa gaatttattc atatcgccac caatcagctc
     6181 atcaaagatg gcaaaactga tgacgacatc aaggcacttc ttgaggaggt cattccgacc
     6241 atcttagaga accagaaaaa aggcatcact gcaagaagcc tatacggggc tccaactgcc
     6301 tgggcagctt cctttagtaa agaagcaaat caaaaagaag ccacacccaa aaacaccaat
     6361 ccatggctga tgtggcttga tacctcgctt ctatttatcg gtattgttgg ccttttaaac
     6421 agtatcatga ccttctttaa taccaacact accgttaccg ggcttgtgtc cttgcttgct
     6481 cttggctttg gagggggtgc ttccatgtac gccacctact attttgttta tcgccatatg
     6541 ggcaaggaca agagccttcg tccaagctgg tttaaggtta ttggtgctct gacacttgca
     6601 atgctggcct ggataaccct ctattctgct acagcctttt taccaaaggc gctcaaccca
     6661 caattacctc ctgtagcact tctcattacc ggtgccttag ctatcggact gcgttacctc
     6721 ttgcagcgca aatacaatat ccaaaacact atggcaccgc agcgctagca gcagctccac
     6781 tgcctgagga agcacttccc tattctctct tgagggcagt tagccttttc ataccatatt
     6841 gctggcaaca ccagacactg atctacaatc gacactcctc aatcc
//
LOCUS       DARYMD010000077         6802 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.078, whole genome shotgun sequence.
ACCESSION   DARYMD010000077 DARYMD010000000
VERSION     DARYMD010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6802
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..692)
                     /locus_tag="TU818_001818"
     CDS             complement(<1..692)
                     /locus_tag="TU818_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HEL0924601.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLAT"
     gene            complement(819..2435)
                     /locus_tag="TU818_001819"
     CDS             complement(819..2435)
                     /locus_tag="TU818_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0924602.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADECLNMGF
                     LEDIEAIISRVPDDRQTLLFSATMPAPIKEIGVKFMKDPEHVQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNVYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(2851..4395)
                     /locus_tag="TU818_001820"
     CDS             complement(2851..4395)
                     /locus_tag="TU818_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL0924603.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDIEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTTDQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLSVSKNLFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(4564..5259)
                     /locus_tag="TU818_001821"
     CDS             complement(4564..5259)
                     /locus_tag="TU818_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL0924604.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSVMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLVGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EANQLELKLSKER"
     gene            complement(5343..6728)
                     /locus_tag="TU818_001822"
     CDS             complement(5343..6728)
                     /locus_tag="TU818_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL0924605.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIALLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNREDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKSS"
BASE COUNT         2026 a         1625 c         1262 g         1889 t
ORIGIN      
        1 gtcgctaaaa aaatagagcc taaaatgaaa ataccccgat gattttccgg actaaccaat
       61 aagtgcagcg cataataggg attgatagcc tttaggattt ccaaatgctg taagctattc
      121 aagagaccac tgatccccaa aacgctaaac caaaccagca tgactggccc aaataattta
      181 ccaataacac ccgttccaaa gcgctgcagg ccaaacaaga ccatcaatat cagcaaggtc
      241 gttaggatca cattggtctg attctggtaa atactgctga gctcaggaac agcctttaag
      301 ccttcaatgg ctgatgtgac cgtaacagct ggtgtcaagg caccatctga taagagcgtt
      361 gctcccccaa gcatagctgg aatgattaac caccttgaca tccttctaac taaggtaaag
      421 agtgaaaaaa tccctccctc atgatgatta tcagccttta aagcaatcaa aacatacttg
      481 attgtcgtta ccaaggttag agtccaaata atcaaggata ctgagcctaa aataaaagct
      541 tcagacacct gtgaaaggcc gccttgattg tcaaccaacg actgcatggt atacagtgga
      601 cttgtgccaa tatcaccata gacaattcct agtgcaataa taaaacctgc ctttgttgct
      661 ttatcaaagg catcatgatg ggcattagac atcccaatgt tcctcctaag acttaatcat
      721 gccaaatgga ctgagaccat tatagcaaaa tctataacaa aatcaatatt ttcagaaaat
      781 taaaaagaga gctgacaatc atcagctctc ttgaaacttt agttcccttt atgacggata
      841 ataaatccag acgtcttagc ttcgacagcc ttgcccttct tgtgcaggtc cttgttagag
      901 cgtttttgct ttcgcttaaa gtcatagcta ccactgctat catgactgtc acgtttatca
      961 cgccttggac ggcggtcacc atcataaaca tttcttttct catgacgata gccacctcga
     1021 cggttatcac gaccgctacg actacgattg ccacgacctg tcttgccatt tttattgcca
     1081 tgaccaccac caacatactt aaacggtaat ggcttttcac gcgctatctc aacctctggt
     1141 aaggtatctg gatcttggac ggtcaagcta aggatataga gcgctagctc ctctggggta
     1201 aactctgctg ccaatttcat cgcatcgccc ttaaatttct caaagtttga gcgaatagca
     1261 tcatctgcaa aatcacgctc aatttttttg agggcaacct ttttcttagc ctgaaaggct
     1321 tcctctgccg tagctggctt gagtggcttc atgcgcttct tagtcaggtg ctcaatcatg
     1381 gtcagatagc ccatctcatt tggtgagaca aaggtaatgg attcccctga cttacctgca
     1441 cgaccggtcc ggccaatacg gtgcacatag ctttctggat cctgtgtaat atcgtaattg
     1501 tacacatgag taacgcctga aatatcaagc ccacgcgcag caacatcggt tgccactaaa
     1561 atatcaagtt gatcattttt aaagtcgcgt atgacacgaa ggcgcttatt ttggtcaagg
     1621 tcaccatgta tcccttctgc gcgaaaacca cgcaatttta agccgcgcgt gatttcatca
     1681 acacgacgct ttgtgcgacc aaatacaatt gatagctctg gctgctgaac gtccatcaga
     1741 cgtgtcatgg tatcaaattt ttcttgctcc ttaacacgca catagtattg atcaacattc
     1801 acatttgtta attccttgtt tttaacctga acatgctcag gatccttcat aaacttgaca
     1861 ccaatttcct tgattggagc tggcattgtt gctgaaaata acagggtttg acgatcgtca
     1921 gggacacgac taataatcgc ttcaatgtcc tctaaaaatc ccatattcaa gcattcatca
     1981 gcttcatcta aaatgagtgt ctcaacatgg tctagcctca aggccttacg cttaatcaaa
     2041 tctaacagac gtcctggcgt tccaacaacg acatgcgccc cagactttag ggccttaatt
     2101 tgcttctcaa tgcttgagcc accatatact gagcgaacct tgacgccttt atcacgacca
     2161 aaacggaaca gctcttcctg actttggaca gccagctcac gcgtcggagc aatcaccaat
     2221 gcctgaatgg tgttatcggc tgtacgaatc ttattcagag ttggtagacc aaaggctgct
     2281 gtttttcctg ttcctgtctg agcctgtccg ataacatctc gtccctccaa ggctaacgga
     2341 atggtcagct cctgaatagg agaggctttt tcaaagcctg ctgtaacaac agctgactga
     2401 atatcttctg ataagttaaa tgctgtaaat ttcaattgtt tctcttttct aaaaaggcag
     2461 tgcgaagctg ccttataaac cttttaatat tgtcgttcga ttaacaacct atttagtgta
     2521 acataattaa tattaaaaag ataggaaata agccatgaaa gtgtttttat ctcaaaatga
     2581 ttaacactat caggcagcta aattgataaa agcgtcactc cttattgctg attggctaac
     2641 agcctcaaaa aggcctcgtc ggacttgctt acctatgctt tttatctact ctgctaaaaa
     2701 gactcggcac agagacgagc cttcgcgatt ccatcaccaa tcttcaaaga cagcaattag
     2761 gattcctgaa agctccttat gccaatagcc tgccttttct tagcagcaga agtgcaaaaa
     2821 cggactaggt tcccctaatc cgcttagctg ctacattttt gcttctagct taacatctgg
     2881 gtatttatct gcaaaccaac gaagcgcaaa gtcattttca aagagaaaaa caggctgatc
     2941 aaagcgatcc cttgccaaaa tgtttcggct tgaggacatg cgttggtcca aatcctcctc
     3001 tgagatccaa cgaacagtct ttttgcccat tggtgtcatg atgacctctg cattgtactc
     3061 accctccata cggtgcttga aaacctcaaa ctgcagctga ccaactgcgc ccagcatgta
     3121 ttcacctgtc tgataattct tataaagctg aacagccccc tcctgtacaa gctgctcaat
     3181 acctttgtgg aaagattttt gcttcatgac attcttaggt gcaaccttca taaaaatctc
     3241 tggggtaaag gtcggcaatg gctcaaattc aaacaggttt ttactaacgc tcaaggtatc
     3301 tccaacctga taagtccctg tatcgtagac cccaataata tcaccggcaa ctgcattttg
     3361 gacattttca cgagactcag ccataaactg agtaacattt gatagcttaa cgcttttacc
     3421 tgtacgagac agctttacag ccattccctt ttgaaactct ccagagacaa tacgcacaaa
     3481 ggcaatgcgg tcacgatgct tagggtccat gttagcctga atcttaaaga caaagcctga
     3541 aaaatcctga ttgaggggat caatcatctg gtccgttgtc gtcttatgcc catgaggctc
     3601 tggtgcaaag gctaaaaagg tatctaaaaa ggtttgtacc ccaaaatttg ttaaggcaga
     3661 gccaaagaat accggagtca gctgaccatc taaaatagcc tgctctgaaa agtcattacc
     3721 tgcctcctcc aagagctcaa tatcttcaag cacctgctca taaaaagggt tgctggcaaa
     3781 aatccttgcc ccctcctcta aatcagcaaa cctctgctcc cccttataaa gctccaagcg
     3841 tttgttgtgc aaatcataca gaccttcaaa ggctcgtccc ataccaattg gccagttcat
     3901 ggggtaagaa gcaatcccaa gaacctcttc tagctcctcc aacaactcca aaggctcacg
     3961 tccatcacga tctaatttat taataaacgt aaaaacaggt atgttacgat gcttaacaac
     4021 ctcaaagagc tttttcgtct gtgcttcgat ccctttagcc gaatcaacaa ccatcacagc
     4081 agcatcaact gccattaagg tacgataagt atcctctgaa aagtcctcgt gaccaggtgt
     4141 atctaaaata ttgatacgct taccagcata atcaaactgc atgactgatg atgtgactga
     4201 aatcccacgt tgcttttcaa tatccatcca atctgactta gcaaattgac cagatttttt
     4261 tcctttaacg gtcccagcct cacgaatctc accaccaaaa taaagtaact gttctgtaat
     4321 agttgtttta ccagcatctg ggtgactgat aatcgcaaag gttcgacgct ttttaatttc
     4381 ttctgtaatt gacattcttt tttccttatt tgttcacatt gcagagcaag actctgatta
     4441 atagcttcaa gtcacacgtc acagttatgt ctacatgatc tcactcctaa atactgatat
     4501 gataaaaaga gctgctagag cagctccttt attatagctg attcgaagcg ctttttcaac
     4561 gccctatctt tctttagaga gcttcagctc taactgattg gcctcactaa atctcacata
     4621 gataagttca atcagcttaa ttaaaccagt caaccccatt gtcacaatga caaaattcat
     4681 aagcaggtga tgcgtatgaa taatcggaat atccatcaca aagccgtaat ttccctttgt
     4741 tgccaaattg atcaatacta aaacaaaatt aatggttgcc aagtaacggc aaacaaggac
     4801 tggctttagc tgacttggat tgtaaaaccg cagcaggtaa accaagccat tgaccaaaag
     4861 agcataatgc cccaggtaaa aagaaatatt agccacatgc catagctgat aagggtataa
     4921 atcaggtgat aacagggcca aaaaggtccc accaatccct aaaaccataa aaagctgctt
     4981 taagctactg cgatccggta agaaaaagat agctagcatg gccattcggc aatggtaaag
     5041 cggcaaagcc tctgtcaacg gaaagcctcg caaggcatac cagctataca aaccaaccaa
     5101 ttggaccaac tgaagcccta agaagatata gcgatacgac tttagctgat agagctgcag
     5161 ggtcataaaa accaaaaacg gcgctatcat caccgacaat agataaaata gcaaggacac
     5221 atgcggtagc ccaataggtt caattgcaaa aaaattcata aacatccctt tctacatttt
     5281 ttcattatac cttaatctta atgagaggac aagatgtttc atgtgttttt tctgaaaaag
     5341 tgttaggagg acttcccagc atgaggagct gtcaggcgat caaccacatt tgctagcagc
     5401 atggagtggc tgccctttag cagcatctgg tcattaggct caagaatagt caacaggtac
     5461 tggcacatgt cctcgtattg atcctctcga ttattctttt taaagaagct aactctgcca
     5521 cttggataat cttgactagc tagcttggcc aaggcttgaa tatcatcacc gtaaaagacc
     5581 aattgatcaa tacgcttggg atctaagctg gtaatcagct gagaatgcaa agcaactgag
     5641 tcagcaccta attccttcat atcagctaaa acagctattt ttttgccatt agggttggcc
     5701 ggaatggcag caaaggtttc caaaattaac cgcatagcag ttggattggc attgtacaca
     5761 tctgccaaaa ggtcggcgcc attagccgcc ttgacccact cggttcggtg gcgtgtcagc
     5821 ttgacggttt ctaaagcttc tataatatcc tcatcaggca cagccaagag tttaccaaca
     5881 taagctgcta tcatagcatt ggttgcattg tattttccag ttaagggaag agtgaccggt
     5941 cttggtaaga cattagtcct aaaggtcaag gagtccttgc actctttgat atcctcaacc
     6001 accagctctt gatgatcgcc aaagcgaatg accatctgac tatccggcaa atatggatca
     6061 aggataggat caccaggagc aattaaaatc ccgttagagt ccatcccatc aacgatttgc
     6121 attttccctt cggcaatctt ctcgcgagag ccaaagtagg ctaagtgagc ctcaccaata
     6181 agggttagca atgcaatatg aggtctggca attctagaga gcagctgaat gtctcccata
     6241 tgatcctgcc ccatctctaa aacaatcttc tcagtatcct ctggcatgtg aagcaccgta
     6301 taaggcaagc caatgtcatt attataattg ccctgggttt tgtaggtctt ataagctttt
     6361 gccaggaccg cttcaatcat atccttggtt gatgttttac cgtttgagcc tgttacagca
     6421 atgacatcga cacgtagctt atcaatataa tactgggcta atttttgaaa ggcagccaag
     6481 caattctcaa ctagtatata gggtctgcca ctgattgctc tttctgaaaa ggtagctacg
     6541 gccccatttt caaaggctaa gtcaataaaa tcatggccat ctcgctcacc ctgtagcggt
     6601 aaaaaaagat caccttttgt gatgtttcta ctgtcaaatt caatctgatt cagaggaacg
     6661 tcgtctaaat cagaaagact attttgagca tcaacaactc ttgccacttc atgtaatgtt
     6721 aatttcatct tatttttcct cttaaaacac tggtttttaa agctttgctt atattatagc
     6781 ataacatatt aggaatattc tt
//
LOCUS       DARYMD010000078         6735 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYMD010000078 DARYMD010000000
VERSION     DARYMD010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6735
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            85..366
                     /locus_tag="TU818_001823"
     CDS             85..366
                     /locus_tag="TU818_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL0924606.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
     gene            complement(492..917)
                     /locus_tag="TU818_001824"
     CDS             complement(492..917)
                     /locus_tag="TU818_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL0924607.1"
                     /translation="MSNFFKTLVIGVASGAATAYFLSTEKGKVLKARAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     ASEHDKADDVIIDLDEEDIIINYPEDDSEKEAASNKSEE"
     gene            complement(914..1318)
                     /locus_tag="TU818_001825"
     CDS             complement(914..1318)
                     /locus_tag="TU818_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL0924608.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIVVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            complement(1340..2119)
                     /locus_tag="TU818_001826"
     CDS             complement(1340..2119)
                     /locus_tag="TU818_001826"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL0924609.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            complement(2116..3048)
                     /locus_tag="TU818_001827"
     CDS             complement(2116..3048)
                     /locus_tag="TU818_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL0924610.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            complement(3326..3598)
                     /locus_tag="TU818_001828"
     CDS             complement(3326..3598)
                     /locus_tag="TU818_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL0924611.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            complement(3662..4099)
                     /locus_tag="TU818_001829"
     CDS             complement(3662..4099)
                     /locus_tag="TU818_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL0924612.1"
                     /translation="MSLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQDCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            complement(4086..6218)
                     /locus_tag="TU818_001830"
     CDS             complement(4086..6218)
                     /locus_tag="TU818_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL0924613.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLTLTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLRERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLETKAEAFITEGFSDPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYAFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLISPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELTVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRESD"
     gene            complement(6386..6712)
                     /locus_tag="TU818_001831"
     CDS             complement(6386..6712)
                     /locus_tag="TU818_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924614.1"
                     /translation="MKKLLLTSAAALALATVAVSTTKVEAFSRGHVIEHTINDTKSLS
                     AARWGSRLQILNLLTRFKHKLGEDGFRSYNRQFRARVGAAKSVSEIDELYNKFEKELE
                     ELEDLT"
BASE COUNT         1938 a         1628 c         1255 g         1914 t
ORIGIN      
        1 aacgagaagc cttcaaaaaa aaagatgaca accatcagct tttatggtaa aatggttggg
       61 tatcttacgg gaaaggagag gactatgcct acaccattgg agcagcggca gctcaagcag
      121 cagaagcaag agcaggtctc gcagcaaaaa tttcaagagt ttcaagacct caatggacac
      181 agtagcaagc tcaaggaact tatttttttt gcccgtattg ctgtttttag tttaatcact
      241 gtcttgtttg catttgtcct tcttgtcatg aatttggcac cggtttgggc ctttctaatt
      301 gctagtgcta tcagcctagc catcacttcc tttctttcaa aggccatcac gttattaatg
      361 tcataaacag ttagagcttg gcttcgctaa gctctttttt cattactctt attgcctatt
      421 ttcttgaata aacgagtagc ccacatcaca aaaggccctc catagctgag agagccctta
      481 tttttgcctt attattcttc agacttattg ctagctgctt ctttttctga atcatcttca
      541 ggatagttga taataatatc ctcttcatcc agatcaataa tcacatcatc agccttgtca
      601 tgctctgaag cagcttcctt tgcctgatga acaaattggc tggtcttttc cttgataaaa
      661 tcaaacacct gatcagtggt catatcccct gattcaaacc tggtttttaa atcattaaag
      721 gtatggcgag ccagctgact gtactcactt cctttttctt tagccatttg atgatattcc
      781 tcaggatttt gacgataggc ttcataggcc ctttgtgcgc gagccttcaa gacctttcct
      841 ttttcagttg acaagaaata agcggtagct gctcctgaag ctacaccaat caccaacgtt
      901 ttaaaaaaat tactcatgac cttttctcct ttttaccaaa taatttagaa gcgaccttgc
      961 cgacaagagc tactttaccc acctttgcag cattgcttgt ggcatttgtc gcccgacgtc
     1021 caaggtgtct ggcctgcaca ttcaaatcag aaacactttc tgacaaatct gcaatagcaa
     1081 caaagagagg atctattgtt gtcatcttac cattcacatc atctaccagc acattagcct
     1141 tagctaatat ttcattggtt tgataaaggg taacattgac atcactcgtt aaaacggtaa
     1201 tggttttttt agcctcatca actgcctctg acaccttttt taacaccaca atcaaaaaaa
     1261 taaccagagc aacaaaggct aatgcgatta tcagcaatga aatgcccact aaattcataa
     1321 acgtctcctc tttctatccc tattcttgat aataagaaat tcccttttgt cgatgccttt
     1381 taaagataaa aacaatcgca atgataatga gcagcaccga catgtattga gaaacacgaa
     1441 ttcctaaaag catcaggctg tccgttcgca tgccctcaat caccaatcga ccacagccat
     1501 accaaatcag gtaaaatgag ataatatccc catctactaa tgacctgggc ttacgccgcc
     1561 acaccatgat aatgacaaag ccaatcaggt tccacatgga ctcatataaa aaggtgggaa
     1621 cacgatagct gccatctata aacatctgct ggcgaataaa actaggcagg taattgagct
     1681 ggctgacagc cctgccatag gcctcttggt taaagaaatt tccccatctg ccgatggcct
     1741 gagcaagcat gacactaggc gctgcaatat ctaagaaatg gataggattc agcaccttat
     1801 agtagcaata aacaaagaga acaatggtac ctgttatcaa gccgccatag atggcaatcc
     1861 caccattcca aatagcaaag atatcactca aatgctgaga ataataggac cattcaaagg
     1921 ctacataata gattcttgct ccaataattg ccaaaggaaa ggcaatcaga ataaaatcaa
     1981 taatatcatc actggtcatt ttttttcgcg gggcttcttt ggctgccaaa taaaccgcta
     2041 aaagtaatcc caccaagata caaaccgcat accagtgaag actaagagga ccaagcttaa
     2101 aggctattgg attgatcatt tgccctcctc atttttgctg attaaacgtg taaggcgctc
     2161 ctcaaaggtt ttggtagcat caaagcccat ctctttcgca cgatggttca tggcagcagc
     2221 ctcaataacc actgacacat ttcgacctgt tttgacagga atgcgaatcc ttggaatact
     2281 gacaccagaa aaggtaatct cttcattgcc attgcccaag cggtcaaaga ccttgccagc
     2341 ctcaaaattc tccaaataaa tagccaactg cacctgtgag gaatccttga cagcactagc
     2401 accgtacagc gacatgacat caataatgcc aacaccacga atctcaagga gatgacgtaa
     2461 aatctctgct ggctcccccc atagcgtctc ctcatcttta gcaaagacat ctactcggtc
     2521 gtctgccacc aagcgatggc cacgcttgac caactctaag cctgtctcac ttttaccaat
     2581 acctgaatca ccttggatca gcacccccat accgtaaata tccatcagca ccccatgcac
     2641 acttgttcgc tctgctaagg aagcatcaag aaaataagac atctcaccag ctaagcggct
     2701 ggtagatacg cggctgctaa acagagcaat accttcctcc tgcgctgcct gaaccatctc
     2761 ctctgggata gctaggcccc tagatacaat cacagctggc gtgtcttttt taaacatttc
     2821 ctttaagact gagtagcgat tgtgtgaggt catctgagtg aggtaggacc attctttcat
     2881 gccaaacagc tgaagccgct ctggggcata gtaatcaaaa tagccggtca tctcaagacc
     2941 cggacgcgaa atatctgagg tcgttatctc cttttctagc aagtcatcag ttgcatagac
     3001 aacgtcaagc ttgacctttg tgactaacat cttaacggta actgtcataa tttctccttt
     3061 tttaatatta tatcataaat cactatctaa gcccttacaa atacttattt ttcaaagaag
     3121 ctttcaaagt gcttgatcat actaaaaaag aatcctgcaa cagctgcctc aggctcactt
     3181 aaagcaggca ctagcctaaa gcggacaaac aacaaaaggc cctatctcat cagataaagg
     3241 cctacagcca gctttatttc tgataatcac gctagaggca ctattaaaat tcctgtcaag
     3301 cttttaatag tcgctcgctg tggtcttacc aaaaccagcc ttcatcttca tcatttagga
     3361 catcagcatc cttgcgacgt cttggtcctc tcccgtaacg ttcttcaagt aggtcctctt
     3421 tatatggtag gaagatggct aaaagaatat aaataacaac cccaaagcga gtaaaataga
     3481 tcaataaggc ggcaagcaca cgagctaggg gcaaatccca gccgtattta tcagctaaac
     3541 cagagataac tccagccact agcttatgct ttcgttgctt ataaaattta gattccatgt
     3601 ctcctcgcct ccttattcta tgatactagt ttattccttt tttagcaaaa taaaatcagc
     3661 cttacgactg atttttttca atgagcctgc catgacacct gccgcaggca aataccgcca
     3721 gattgatagg acgttttcgg tcataagctt ggccgcaatc ttgacagatg tagaggtaat
     3781 tagcttgatg tgactgtaat tttggagcgt atctcagacc gtctacttgg tctagaagct
     3841 ccttaaaggc ttgatcctta tgccgaaagc ccagcccctc aaaatagagg tgataatgac
     3901 aaagctcatg cctaacgatc tgtctaaaga cagtctcccc atgctcctct aagattttgg
     3961 gattgaaatc cagatgacca tcctttggaa aaaaacgtcc gcctgttgtt cttagtcgtc
     4021 tgttccaaga agcctgatgc ttaaagggct ttccaaaatc agctagcgag acctctctaa
     4081 cataatcagt cagactcacg aggcggcact aagcttaggt tgaccttgtg gcggtctaag
     4141 tcaaccttag aaacccaaac agtgactaaa tctccgacag aaacgacctg acttgggtga
     4201 ttgacaaagg cctcactcat ctctgaaatg tgaatcaaac cgtcctcatg tacaccaata
     4261 tcaacaaaag caccgaagtc aaccacattt ctaacagttc cctctagcct ttgaccaaca
     4321 gccagatcct ttacactcaa aatgtccttt cgaagaacag gagcttcaaa gtcatcacgc
     4381 aagtctcttc ctggcttcag caaatcagca atgatatcct tgagcgtttc ttgaccaagc
     4441 gtcaattgct ctgccatttc ctcaagatta accgcctgta atttggccct tgcaggctca
     4501 tctaagtctt taatcgcaag taattgaaag agctttttga cagccggata ggcttctggg
     4561 tgaacgcctg tattgtctaa tatattctta gcattgggaa tacgcaagaa gcctgctgcc
     4621 tgctcaaagg cctttgcgcc tagtctaggg acctttttga tctcagcacg tgaggtgatc
     4681 tctccatttt cttcacgata cctgacgata ttctcagaaa tggttttatt tagccctgaa
     4741 acatgagcca gtagggctgg actagctgta ttgatgttaa ccccaacctg attaacaacg
     4801 gtatcaacga caaaatccag atgctcagat agctttttct gactaacatc atgctggtat
     4861 tgtccgacac cgattgcttt tgggtcaatt ttgaccagct ctgctagcgg gtcttgcaag
     4921 cgacgcgcaa tagagatggc tgagcgcttt tcaaccgtca gctctggaaa ttcatggcgg
     4981 gctagctctg aggccgaata aaccgaagct ccgctttcat taacaatgac ataagaggtt
     5041 tctggaaaat cctttagcac ctctgcaaca aaggcttcac tctcacgact ggctgtgcca
     5101 ttaccaatgg caataatatc aatctgatag tcagtgatga gctgagctag agctactctt
     5161 gctgcttgaa tcttagcttg attagctggt gccaccggat agataacctg agtagttaac
     5221 agctttccag tcggatcaat caccgctaat ttggcccctg tcctaaaggc cgggtcaaag
     5281 cccagcacca tttttccctt tagtggtgaa attagcaaaa gatgacgcaa attttccgaa
     5341 aagagcttga tagcaccgtc ctcagccatt tcagttaatt ctgtgcggat acgtcgttcc
     5401 atagcaggaa caattttttt cttgattgtt tggttaataa catcatcaat ataagcattg
     5461 tgctccttaa agcgaaggct gaaaaagcgc agcattttgt ctatatgatg ctcaaaggat
     5521 acctttaata cgcctagctt ttccccacga ttgagagcta gggtcctgta gccctgcatg
     5581 ttagataccg tctcagaaaa cgcatagtaa atctgaaaga cctgcttgtc atctaagctg
     5641 gcttccttta ggctagaggt tatacggcta tacttccaaa tctcattata ggtccaggac
     5701 cttagcctgc tatcctctga catggcttcg accaaaatat caacagctcc agcaagggct
     5761 gcctgtggat ccgaaaaacc ttctgtgata aaggcctctg ccttagtttc taggtcttgt
     5821 gcattttgaa ggatcagtct agctagtcca gataagccgg cttctcgagc aatggttgcc
     5881 ttggtacgcc gcttttcctt gtaaggcaaa taaagctcct ctaggtcagc caatttatca
     5941 gctgcttcta tagcttcctt aagggcagct gttagtttcc cttgtccttc gattttagca
     6001 agaatggtgt ctttacgctc cctaagctgt gtgagggact tatccatatc aataatggcc
     6061 ttgatcacca cttcatcaag gttacctgta gcttccttac gatagcgcgc aataaaggga
     6121 atggtattac cctcagcggt aagggtaagc acttgactaa tctgttttgg ggtgaccccc
     6181 aacgcttctg aaatgttttg atgattcata ttttccataa cagttcttat tatagcacaa
     6241 agaaagaggg atagaacaag ataaaagctt tatgacaaat aagtgtcaag aaaacaaaac
     6301 ttatcttttc agatacttct aaaggctaag aaaaaacgat ctccaaacgg aaatcgtctt
     6361 ttagctactt agtggttagt caaaattaag tgagatcttc taactcttcc aactcctttt
     6421 caaacttatt ataaagttca tcaatttcac ttactgattt tgctgcacct accctagctc
     6481 tgaattgtct gttataagac ctaaagccat cctctcctag tttatgctta aatcgtgtta
     6541 acagattaag gatttgcagt cttgaccccc agcgcgctgc actaagcgac ttggtgtcgt
     6601 taatcgtatg ctctataaca tgcccacgag aaaacgcctc tacttttgtt gtgctaactg
     6661 ctactgttgc taaggctagc gctgcagcac tagttaatag taattttttc atgatatgac
     6721 tcctatttgt ttttt
//
LOCUS       DARYMD010000079         5337 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYMD010000079 DARYMD010000000
VERSION     DARYMD010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5337
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(150..389)
                     /locus_tag="TU818_001832"
     CDS             complement(150..389)
                     /locus_tag="TU818_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL0924615.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(548..1036)
                     /locus_tag="TU818_001833"
     CDS             complement(548..1036)
                     /locus_tag="TU818_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0924616.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDGSPFGGSNPMDISDDDL
                     PF"
     gene            complement(1055..1345)
                     /locus_tag="TU818_001834"
     CDS             complement(1055..1345)
                     /locus_tag="TU818_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL0924617.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            2721..3869
                     /gene="mutY"
                     /locus_tag="TU818_001835"
     CDS             2721..3869
                     /gene="mutY"
                     /locus_tag="TU818_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL0924618.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEINYDIGDPKNRKIFQAVMEVLIDPERPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSKGRLLLEKNTQGRLLGGFWAFP
                     LIETKLVSQQLTLFEDSPIVLETMSQTTLFEERYGLMPIWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLEAYLKKQS"
     gene            4640..>5337
                     /locus_tag="TU818_001836"
     CDS             4640..>5337
                     /locus_tag="TU818_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface-anchored protein"
                     /protein_id="HEL0924619.1"
                     /translation="MNKKSARRRRKNLITKLAMTSALTLGVGAATTLAGQTEVRADNI
                     LRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQ
                     KVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAK
                     NAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKA
                     QIEKLKHCQDTPKP"
BASE COUNT         1627 a         1169 c         1064 g         1477 t
ORIGIN      
        1 cttagatgag gagtttttct ttagccctat gcttcatcaa acaccaccag ataccacact
       61 ctcaatcaga tcacaggcta aggcttgacg acgctgctca gctgacttca gaccacataa
      121 aaaacagccc ttaaggactg tttcagatat tagtcttcgt ttacgtaagg cataagtgcc
      181 ataacacgag cacgtttgat agctgttgtt actttacgtt ggtttttagc tgatgttcct
      241 gttacacgac gaggaaggat tttcccacgt tctgaaacga aacggctaag aagctcagta
      301 tctttgtaat caacatattc aattttgtta gctgcgataa agtcaacttt tttacggcgc
      361 ttgaatccgc cacgacgttg ttgagccatg tgttatctcc tttatattat tcacatgata
      421 aatttgctgc ctaataagca aaccgacgcc agaaagaggc ctcaatcttt tgtgcttgaa
      481 agcaactcct ctgtctccca agctaccagc aaatctatgc aattcatgtc agtccacttt
      541 ccattgctta gaatggaaga tcgtcatctg aaatatccat tggatttgag ccgccaaatg
      601 gacttccatc tctgccaaag ttaggtgttt gctgagcagg cgctgaatag ctattggttg
      661 ccggtgagct attaaaacca ccaccatatg agccagacga gttcgcctca cgtgtagcac
      721 gactttccag catttggaaa ttatctgcaa caacctcggt tacatacaca cgctgcccct
      781 gttggttttc gtagttacga gtctgaatac gtcccgtaat cccaatcaag gcaccctttt
      841 tagcccagtt agctaaattt tcagcttgct gacgccagat cacacagtta atgaaatccg
      901 cttcgcgctc accattttgg ctcttaaagg cgcgattaac agcaagtgta aacgtagcaa
      961 ctgccacctg acttggagtg tatcgaagct ctgcgtcctt ggtcatacga ccaactagta
     1021 ctacattatt aatcataaac tacctacttt gcaattaagc gtcaagctta acgatcatgt
     1081 gacgaagaat gtcaccgttg atttttgaca gacggtcaaa ctcattaaga gctacagcgt
     1141 cagtcgcttc aaggtttacg atatggtaaa ggccttcgcg gaaatcattg atttcgtatg
     1201 caagacgacg cttttcccaa tcttttgatt caacaatagt tgcaccattg tcagtcaaga
     1261 tagagtcaaa acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga
     1321 tataaagaat ttcgtattta gccattgata gtttcctcct tttggtctaa tgactcgcta
     1381 cccttgtaac gagtaagtga ggtatgctca cagattaaca gtatacaata aacaaaggta
     1441 aaaagcaagc aaaatgttga cctttctgtt gaataaaaga ccttcttaga tcccttcgta
     1501 gctccataaa aagcaaagcc acttctatag aaatgacctt tagtcacctg acttgcaggt
     1561 cttagtggca aggtcaaatc cagacaccag caaaaaggac acccaaccgg gtgtccttat
     1621 catgtcttga gtgctattct cccttctatc tgccatttaa taaggagtca cctgtcaatt
     1681 gttcctctaa agaggaacac atacttatct gtctaatcag tcgtctcctt tctgtttaac
     1741 aaaatgaacg gttattaaaa gaatatgact gttcttgagt ttcgtttgtt agcactgtgc
     1801 tattttggct tacattggac tcactccttc agctattttt tgctgtcgtg ctcaatgtct
     1861 ccgtttttat atcttgcgat gtacataaga ccctcctatt agaaaagctc actagctatc
     1921 tgatgatagc tacctttcaa ataagctcaa tcctttaccc tgagtgccaa taacaatatc
     1981 aaggacgact agtgacacag caactagtct ccatttttat agcgtccttt attgaatctt
     2041 agcatagcat acgtcctttc aataacggga atttcaagct tatactgttt agagcgctcc
     2101 tttggccaaa gctggtaatc tcgataagcc ttcacatgtg atcacatatt aaattgtaaa
     2161 attggttttg cctaccgttt gttggagctc ttaatctcca tttttgtacc gcgcgacatg
     2221 tcttgttatc atcagatatc ctcctataac tccagtgtca tcggtcgtcc ttatctacat
     2281 ctttattata atgtaagcgg ttactaaagt caagcttttt gctccttttt tgataacata
     2341 tcagcaacta aaaccccacg ataggacaca agccttcagc aaagactgag aaccttttta
     2401 tacttgtcat ttacgttcaa gtgcctttgt caatacctca gagtcattaa ccttttcgcg
     2461 gtcagctaat ctaaccaacc actctgaaac ggtaacagtt ttacgaacag ctttattatt
     2521 tttgataaat ggtgttgaat cagcttgtag gaactggtaa attcagacca caatcaatat
     2581 aagcagcaag aacattttct aacatgtcat gagcagttgt cacagcctct ttataaggta
     2641 taaatcacaa agcatgcttt aacaaatcct atcggacgca gggttcaacc aattcagaca
     2701 atctgtgtta caataggatt atgatagatt taaatgatta tggcattacc atgtgggatc
     2761 aagataccat tgcctccttt cgtcgtacgc tgctagcttg gtacgatcag gaaaagcgag
     2821 acctgccttg gcgtcgcaca aaggaccctt atcatatctg ggtctcagag atcatgctcc
     2881 agcaaacgca ggtcgttacc gttattcctt attacgagcg atttttggat tggtttccaa
     2941 cggtagaggc cctcgcctgc gctgacgaag agcgcttact caaggcttgg gagggactgg
     3001 gctactactc tcgtgtacgc aatatgcaaa aggctgcgca gcaaatcatg actgactttg
     3061 gcgggatttt cccaagctca cacgctgata ttactaagtt aaagggcatt ggcccttata
     3121 cagctggcgc tatctcaagc attgcctttg atctgcctga gcctgcggtt gatggcaatg
     3181 tcatgcgagt catggccaga ctgtttgaga ttaattacga tattggagac cctaagaacc
     3241 gcaagatttt tcaggctgtt atggaggtgc ttatcgatcc ggagcgaccc ggagatttca
     3301 atcaagcctt gatggatctg gggactgata ttgaagcggc taaaaatccc agacctgacg
     3361 agtctcctgt gcgctttttc tgtgcagcct accgacatgg tacctatgac aaatacccca
     3421 tcaaggagcc aaagaaaaag ccccggccta ttcaggtgca ggcctttgtg attcgtgaca
     3481 gcaaggggcg gcttttgctc gaaaaaaata cccaagggcg cttgctaggt ggcttttggg
     3541 cctttcctct gatagagacc aagcttgtca gtcaacaact gaccctcttt gaggacagtc
     3601 ctatcgtgct tgagaccatg tctcagacaa ccctttttga ggagcgttac gggcttatgc
     3661 ctatctggtc tcaagctacc tttcctcagg tcaagcatac ctttagccac caaaaatgga
     3721 ccattgagct ttgcgagggc ttcacagaca gcatgcccct agcccctgac agagaacttg
     3781 tctgggtcgc aatagaggat atggctgctt acccaatggc aaccccacaa aagaaaatgc
     3841 tagaagccta cctaaaaaaa caaagctaag cggctcatag ctgtcagata aggtccttaa
     3901 ggcagagctt tagggacttt tttgcttgcc caaggagctt acttgtagcc tacttggtct
     3961 gatcagacaa gaaaaactcg atttcttgta acaaagtcag acgattaccc ttttcattaa
     4021 aaaaacgaaa ctacggagac aaattgggac actgctatgt cttgtcgtca gctgtcgtgc
     4081 tacactggcc ttagaaacta agcacagcca aaagctgtga aaactataac tatattatgg
     4141 aggagaaaac acaatgaagc tgacaaatgc cctatgccta gtagccgcta ctgcagccct
     4201 agccctagca ccaatcaaca caagcactgg acaaactaat accgttttgg caagtcaaaa
     4261 aagtacagga cattgtactc atactagaag tggatggttt aaatgccctg atggaggatc
     4321 atattacgac gaaagttacg atacacattc atcatggtta atttggcttt atggtgcttt
     4381 ttactctgca tgggaaatta taactagttg gttcaaataa attagtaaag caggtcaggt
     4441 tattatcggc ctgcttttct taatcagcct tgctaatgcc tgctgaattg ccagaaatca
     4501 gacaattagc cttttcatta aaaccaaaaa ccgaacgaat ctaggagaga aagtagcgga
     4561 caactatttc tctatcttga tgactgtgtt aaaatatctt cagtcaaaat taatatgtct
     4621 atcattaaag gagagagaaa tgaacaaaaa atcagcaaga cgcaggcgta agaatcttat
     4681 tacgaagctt gcgatgacaa gtgccttaac cctgggtgta ggcgcagcga ctaccctagc
     4741 aggacaaaca gaagtacggg ctgataatat cttacgctta gatatgacag ataaagaagc
     4801 agttgaaaaa ttcgctaacg agcttaaaaa tgaagtccat aaaaactatc gtggtagtaa
     4861 tacttggcaa aagcttaccc ttatacttaa tggttatcaa aaccttagag aacaaataga
     4921 gaccgagcta aaaaatagtg aacaaaaagt aaaagagctt aatgataagg ttaatagtga
     4981 aactcaagga aaacaagagt tacagaatca gcttgagaaa gaaaaagaag agttagaaac
     5041 actaaaaaaa gagcttgaag ctgagaaggc taaaggaact ggagaaacag agaagcttca
     5101 aaaggaaatt gaagcaaaaa atgcaatgat ttctgaccta caaaaacagc ttgaggaaac
     5161 taagcaaagg gttcaagagt ttgaagctga agtaggtaaa ttaatggccg aaaaggcaga
     5221 cctacaaaca aaattaaatg aacaagagca gcttaacgct aagcttcaaa aagaaattga
     5281 agacttaaag gctcagattg aaaagcttaa gcactgtcaa gatacaccta agccaga
//
LOCUS       DARYMD010000080         5331 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYMD010000080 DARYMD010000000
VERSION     DARYMD010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5331
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            90..1643
                     /locus_tag="TU818_001837"
     rRNA            90..1643
                     /locus_tag="TU818_001837"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1865..1937
                     /locus_tag="TU818_001838"
     tRNA            1865..1937
                     /locus_tag="TU818_001838"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1898..1900,aa:Ala,seq:tgc)
     gene            2245..5144
                     /locus_tag="TU818_001839"
     rRNA            2245..5144
                     /locus_tag="TU818_001839"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5229..>5331
                     /gene="rrf"
                     /locus_tag="TU818_001840"
     rRNA            5229..>5331
                     /gene="rrf"
                     /locus_tag="TU818_001840"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1525 a         1083 c         1543 g         1180 t
ORIGIN      
        1 aagacgacct aaacgtgcgg gttacggaag taacctgtca ataaagaaac aagtcagtaa
       61 tgacgtcgag ttaagagctc aaacactgaa ttaacgagag tttgatcctg gctcaggacg
      121 aacgctggcg gcgtgcctaa tacatgcaag tggaacgcac agatgatacg tagcttgcta
      181 caattatctg tgagtcgcga acgggtgagt aacgcgtagg taacctagct tatagcgggg
      241 gataactatt ggaaacgata gctaataccg cataaaagtg gttgacccat gttaaccatt
      301 taaaaggagc aacagctcca ctatgagatg gacctgcgtt gtattagcta gttggtaggg
      361 taaaggccta ccaaggcgac gatacatagc cgacctgaga gggtgaacgg ccacactggg
      421 actgagacac ggcccagact cctacgggag gcagcagtag ggaatcttcg gcaatggggg
      481 gaaccctgac cgagcaacgc cgcgtgagtg aagaaggttt tcggatcgta aagctctgtt
      541 gttagagaag aacagtgatg ggagtggaaa gtccatcatg tgacggtaac taaccagaaa
      601 gggacggcta actacgtgcc agcagccgcg gtaatacgta ggtcccgagc gttgtccgga
      661 tttattgggc gtaaagcgag cgcaggcggt ttgataagtc tgaagttaaa ggcagtggct
      721 taaccattgt atgctttgga aactgttaaa cttgagtgca gaaggggaga gtggaattcc
      781 atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc ggtggcgaaa gcggctctct
      841 ggtctgtaac tgacgctgag gctcgaaagc gtggggagca aacaggatta gataccctgg
      901 tagtccacgc cgtaaacgct gagtgctagg tgttaggccc tttccggggc ttagtgccgg
      961 agctaacgca ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa
     1021 ttgacggggg cccgcacaag cggtggagca tgtggtttaa ttcgaagcaa cgcgaagaac
     1081 cttaccaggt cttgacatcc cgatgctatt cttagagata agaagttact tcggtacatt
     1141 ggagacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg
     1201 caacgagcgc aacccttatt gttagttgcc atcattaagt tgggcactct agcgagactg
     1261 ccggtaataa accggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgacctg
     1321 ggctacacac gtgctacaat ggttggtaca acgagtcgca agccggtgac ggcaagctaa
     1381 tctctgaaag ccaatctcag ttcggattgt aggctgcaac tcgcctacat gaagtcggaa
     1441 tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt tcccgggcct tgtacacacc
     1501 gcccgtcaca ccacgagagt ttgtaacacc cgaagtcggt gaggtaaccg ttaaggagcc
     1561 agccgcctaa ggtgggatag atgattgggg tgaagtcgta acaaggtagc cgtatcggaa
     1621 ggtgcggctg gatcacctcc tttctaagga aaaaggaagc acgtttagcg tcttatttag
     1681 ttttgagagg tcttgaaata agtcatgaga acgttaagaa acccgtatga caatagggaa
     1741 ctgacgcaga gtcgtaggac tcaaggaagt gattcttttt cactagggtt ttagttcgaa
     1801 tacagtttgg cttcatacag accattgata agagtataca tatacaagta catttatagt
     1861 gtacggggcc ttagctcagc tgggagagcg cctgctttgc acgcaggagg tcagcggttc
     1921 gatcccgcta ggctccatta tctaggatac aaagagaagt ttgggttacc taattttctg
     1981 tattctaaga tatataagat atagttcaag taattgaaca cgacctcatt ttttaggaaa
     2041 aaagataaat ctcctcgtgt gtaaagcaca catcgtcgat ttcctatttt tctacaaaaa
     2101 tgcccaacaa gttgggacgg tcttagtatc ttaatcttgt ccattgaaaa ttgaataact
     2161 atatcatatt ccgcaatcaa aaaagattgt aagaaagtaa caagaaataa accgaaacgc
     2221 tgtgataacg agtttaaaaa ataaggttaa gttaataagg gcgcacggtg gatgccttgg
     2281 cactagaagc cgaagaagga cgtgacaaac gacgaaatgc tttggggagc tgtaagtaag
     2341 caaagatcca gagatgtccg aatgggggaa cccactagct aatggctagt atccataact
     2401 gttaaggtta tgagaaggaa gacgcagtga actgaaacat ctaagtagct gcaggaagag
     2461 aaagcaaacg cgattgcctg agtagcggcg agcgaaaagg caggagggca aaccgaagag
     2521 tttactcttc ggggttgtag gactgcgctg tgggacgaca agattataga agaaggcctt
     2581 gggaagggtc gccaaagaga gtaatagcct cgtattcgaa atagtcttta accctagcag
     2641 tatcctgagt acggcgagac acgaggaatc tcgtcggaat ctgggaggac catctcctaa
     2701 ccctaaatac tcactagtga ccgatagtga accagtaccg tgagggaaag gtgaaaagca
     2761 ccccgggagg ggagtgaaag agaacctgaa accgtgtgcc tacaagaagt tcgagcccgt
     2821 taatgggtga gagcgtgcct tttgtagaat gaaccggcga gttacgttta tgtgcgaggt
     2881 taagttgaag agacggagcc gaagggaaac cgagtcttaa tagggcgtaa gtacgtggac
     2941 gtagacccga aaccatgtga cctacccatg agcaggttga aggtgcggta agacgcactg
     3001 gaggaccgaa ccagggcacg ttgaaaagtg cttggatgac ttgtgggtag cggagaaatt
     3061 ccaaacgaac ttggagatag ctggttctct ccgaaatagc tttagggcta gcgtcgatat
     3121 gaagtctctt ggaggtagag cactgtttgg gtgaggggtc catcccggat taccaatctc
     3181 agataaactc cgaatgccaa tgagatatga tcggcagtca gactgcgagt gctaagatcc
     3241 gtagtcgaaa gggaaacagc ccagaccacc agctaaggtc cccaaataac tgttaagtgg
     3301 aaaaggatgt ggggttgcac agacaactag gatgttagct tagaagcagc tattcattca
     3361 aagagtgcgt aatagctcac tagtcgagtg accctgcgcc gaaaatgtac cggggctaaa
     3421 acagtttacc gaagctgtgg attaccgtta aggtaatggt aggagagcgt tctatgtgtg
     3481 atgaaggtat actgtgaaga gtgctggaac gcatagaagt gagaatgccg gtatgagtag
     3541 cgaaagacag gtgagaatcc tgtccaccgt aagactaagg attccagggg aaggctcgtc
     3601 cgccctgggt tagtcgggac ctaaggagag accgaagggt gtatccgatg gacaacaggt
     3661 tgatattcct gtactagagt atatagtgat ggagggacgc agtaggctaa ctaaaccgga
     3721 cgactggaag agtccggcta agcagtgagg tgtgatgtga gtcaaatgct tacatctata
     3781 acattgagct gtgaagggga gcgaagttaa gtagcgaagt tagagacgtc acactgccaa
     3841 gaaaagcttc tagcgatacg tatactctac ccgtaccgca aaccgacaca ggtagtcgag
     3901 gcgagtagcc tcaggtgatc gagagaactc tcgttaagga actcggcaaa atggccccgt
     3961 aacttcggga gaaggggcgc tgactgaagg tcagccgcag tgaataggcc caagcaactg
     4021 tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg tgacgcctgc
     4081 ccggtgctgg aaggttaaga ggagtgctta gcgcaagcga aggtatgaat tgaagcccca
     4141 gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt
     4201 ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc aacgagagac tcggtgaaat
     4261 tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc atggagcttt
     4321 actgcagttt gatattgagt atctgtacca catgtacagg ataggtagga gccatagaag
     4381 tcgggacgcc agtttcgatg gaggcgatgt tgggatacta cccttgtgtt atggctactc
     4441 taacccggat aggtgatccc tatcggagac agtgtctgac gggcagtttg actggggcgg
     4501 tcgcctccta aaatgtaacg gaggcgccca aaggttccct cagattggtt ggaaatcaat
     4561 cgcagagtgt aaaggtataa gggagcttga ctgcgagagc aacacctcga gcagggacga
     4621 aagtcgggct tagtgatccg gtggtaccgt atggaagggc catcgctcaa cggataaaag
     4681 ctaccctggg gataacaggc ttatctcccc caagagttca catcgacggg gaggtttggc
     4741 acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt tgggctgttc
     4801 gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc
     4861 cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt acgagaggac cagagtggac
     4921 ttaccgctgg tgtaccagtt gtctcgccag aggcatagct gggtagctat gtagggaagg
     4981 gataagcgct gaaagcatct aagtgcgaag ccctcctcaa gatgagattt cccataacgt
     5041 taagttagta agagccctga gagatgatca ggtagatagg ttaggagtgg acgtgtggtg
     5101 acacatggag cggactaata ctaatagctc gaggacttat ccaaaagatg aaaccagtcg
     5161 ctattgacag cttaaggaat tcttgttaga ctatagttat tcaattttga gtggagaaga
     5221 ctcgtaagtt aagtgacgat agcctaggag atacacctgt acccatgccg aacacagtag
     5281 ttaagcccta gaacgcctga agtagttggg ggttgccccc tgtgagatac g
//
LOCUS       DARYMD010000081         5055 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.082, whole genome shotgun sequence.
ACCESSION   DARYMD010000081 DARYMD010000000
VERSION     DARYMD010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5055
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(40..588)
                     /gene="raiA"
                     /locus_tag="TU818_001841"
     CDS             complement(40..588)
                     /gene="raiA"
                     /locus_tag="TU818_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL0924620.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEKAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
     gene            complement(664..1245)
                     /locus_tag="TU818_001842"
     CDS             complement(664..1245)
                     /locus_tag="TU818_001842"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL0924621.1"
                     /translation="MCDACQRHFCRITQPTCSNCYQYRHEGACQDCIAWKRQGYQVDH
                     QSLYQYNTAMKDYFSRYKFQGDYVLRSLFAQELAKHIKKYYKAYTLVPVPVSKQRYDE
                     RGFNQVTAILEYANLAYLDLFERIDDTRQSSKTKKERLQLNNRYRLKKGAALPPKILL
                     IDDIYTTGSTIMSLRQELVRHGCQDIKSLSIAR"
     gene            complement(1473..1658)
                     /locus_tag="TU818_001843"
     CDS             complement(1473..1658)
                     /locus_tag="TU818_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL0924622.1"
                     /translation="MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWE
                     VVTVEAVADILNELQII"
     gene            complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TU818_001844"
     CDS             complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TU818_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeL"
                     /protein_id="HEL0924623.1"
                     /translation="MRIFLRQNCRLVNMSTTFFIVVLSLVVFSVRMVSAEGTISIKDI
                     YSPRWDVDKTLSPTTLREIYNRDTIKKENKPVTGKRGTQVIIDAQHKTKVWEFDDYNF
                     IISSNLYPSVEGKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGKTIY
                     MNVFIDGHKKDETSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYGSKVLSGNW
                     EFHGSGENEEGADLFKYPDYRYNNLIDIDKKSHIDVYLFTNKEN"
     gene            complement(2835..3614)
                     /gene="spek"
                     /locus_tag="TU818_001845"
     CDS             complement(2835..3614)
                     /gene="spek"
                     /locus_tag="TU818_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HEL0924624.1"
                     /translation="MKKNTLALLFLVCVSLTLCTTESVFSDTYNTNDVRNPRNIYAPR
                     YDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKKVISS
                     NLSPSQERMFNVGDHVNIFAIVKSYHVVCKEQFNYIDGGIIKTSDVKPEEKAIYINIF
                     GEKELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFWDIHY
                     KDGGIRHTNLFTYPDYTDNETIDMSKVSHFDVYLNEEFSKN"
     gene            complement(3739..4968)
                     /locus_tag="TU818_001846"
     CDS             complement(3739..4968)
                     /locus_tag="TU818_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0924625.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVIGETDYKKACHAIKAAGYATASDYAELLIQLIEQNDLQKWDAEALAKRKESQMISS
                     QCREVIEFYINLANAGMGVDKDGAYGTQCADVPCYAAKHWFGVDLWGNAADLLDSASA
                     QGWEVHRMPTDANPRAGAFFVMDAWFGGINYGHTGLVYVDSDGYTMQTIEQNIDGNAD
                     ALYVGGPARFNTRDFTNVAGWFYPPYQGDVAAQTVSTDPQTSDTIVETSKSGTFTLDA
                     AEINVRRWPNLTSEVVDSYKQGQTVSFDSEGYANGYYWISYVGGSGKRNYMAIGPTDK
                     DGNIISLWGKLGGKDPR"
BASE COUNT         1483 a         1082 c          801 g         1689 t
ORIGIN      
        1 gcaaaaaaac aagaggtgag atgcctcttg tttttcaaat tattttgctt cgataagtcc
       61 taagtcacca tcctcacgac gataaagaac atttgttgct ccgtcctcag catctgtata
      121 gatgaagaaa tcatgcccta gaagttccat ctgcaagcga gcttcctcaa cgtccattgg
      181 ctttagagtc acatttttcg tgcggaccac tttgatttct ggagtttctt cagctttttc
      241 tgcttcaaat tcactagtaa acacttgact agttgacatt ttttcacgat gctttttggc
      301 aatttttgtt ttattttttc taatttgacg ttcgatttta tcaacgacta aatcaataga
      361 accatacata tcctgtgaaa cgtcttctgc acgaagtgtc actgaaccaa gcggaatagt
      421 gacttcaacc tttgcagtct tttcacgata aacctttaaa ttaacacgcg catctatttc
      481 ttgctcttca acaaaatatt tttcaatctt agtaagcttt gattctacat aatcgcgaat
      541 agcctctgtc acttcgatgt tttctccacg aatactgaat ttaatcataa gagtacctct
      601 ttcttgcgtt taaaacgctt tctttagttc tactatagcc gttttcatga aaatttgcaa
      661 gttttatcgt gcaattgaga gacttttgat gtcctgacag ccatgcctga caagctcctg
      721 ccttagactc attatggtgc taccggttgt atagatatcg tcaattaata agattttcgg
      781 tggaagagct gctccctttt tgagtcgata gcggttattt agctgcaggc gttctttttt
      841 cgttttgctt gattgtctag tatcgtcgat tcgctcaaat aggtcaagat aggctaggtt
      901 ggcatattct aaaatagctg ttacttgatt aaagcccctt tcatcatacc tttgcttgct
      961 aacaggcaca ggaaccaaag tataggcttt ataatacttt ttaatgtgct tagctagctc
     1021 ctgcgcaaaa agactgcgta aaacataatc tccttgaaat ttgtaacggc tgaaataatc
     1081 cttcattgcg gtgttgtatt ggtaaaggct ctgatgatca acctgatagc cttgcctttt
     1141 ccaggcaata caatcctggc aggcgccctc atgacgatac tggtagcaat tagagcaggt
     1201 tggctgagta atcctacaaa aatgacgctg acaggcatca cacataagat ccttattagg
     1261 acttaacaac agaattgctg tgatagacaa gctatcttta ctatttattg tggcagagta
     1321 gacagttcat tttgataccc tttttgattc atgtccttta tctcccgcac tgccttgagc
     1381 atagcctggc taataccatc atgaaaaaat agcacctgtc cttcaggtct ttccaaagag
     1441 cgcccaacgc gacctgaaat ttgaattagc ggtcaaataa tttgtaattc gtttaaaata
     1501 tcagcaactg cctcgactgt caccacttcc caaggctgca cttcctcccc tggcaacaca
     1561 taatcaaata tctgtccgtt tttacgcacg atcatgacca cgtctcctgt gatatatcca
     1621 tgatcaatag cttgcttaaa ttcctcgtat gttagcataa attacctcct tatcttatta
     1681 ttcgtaaaaa tctggtattg gtatattgga cacatttata tgtaccgaac aaaaaaacgc
     1741 cctcaattaa gagggtattc cttggtttct tgatactaac taattttctt tgtttgtgaa
     1801 tagatagaca tcaatatgac tctttttgtc tatatctatc aaattattat atctataatc
     1861 tgggtattta aataagtcag caccttcctc gttctcgcct gagccgtgaa attcccagtt
     1921 tccagataga actttggaac catactgata aagttttatt tcatcgttca gcataaatga
     1981 ttttctcaat ctaacatcaa cctcctggaa ggtaacggga gatttttcaa aagttatttt
     2041 atatttcgag gtctcatctt tcttatgccc atcaataaaa acgttcatgt aaatcgtttt
     2101 tccagctcct tttctctcat taactttaac gagaccacca ttgattgaat gtatttgatc
     2161 ttttgaaaat acttcagccg ataatgcaag accaaaaaca tcgacattat ctccaacatt
     2221 aaatttacct tctacagatg ggtataggtt acttgatatt ataaaattat aatcatcaaa
     2281 ttcccatact ttagttttat gctgagcatc tataataact tgcgtccctc tttttccagt
     2341 aacgggttta ttctcttttt ttatagtatc tctattataa atttctctta aggtagtagg
     2401 ggataatgtt ttatctacat cccaccttgg agagtatata tccttaatac taatagtccc
     2461 ctccgcagaa accatcctaa cagaaaatac caccaatgac aatactacta taaaaaaagt
     2521 agttgacata ttaaccaaac gacaattctg acgtaaaaaa attctcattt atcttattat
     2581 tctccttaat aaatcaatat agctgtgaaa ctatgttttt tgaacttgaa cctcaaaatg
     2641 cttaaatcgg aagtacttga gcagacttct taaaagataa taaactgatt ctataacgca
     2701 cagaaattaa tctgagcggt tttatcatat tcctcggttg accgatagtg atgcctagaa
     2761 gtctactaaa accgtctaat tcatcaaaat ctatttaaat agactaaaaa ttaaattaaa
     2821 atagcattcg accgttaatt tttagaaaat tcttcgttta agtaaacatc aaagtgacta
     2881 actttactca tatcaatcgt ttcattatct gtatagtcgg ggtaagtaaa taaattggtg
     2941 tgtctaatgc caccgtcttt ataatgaata tcccaaaacc cttttttata caaagaatcg
     3001 tactcataca attttatttt gctgtctccc atcaaacttt tcctaagtct aacatcaatc
     3061 tcctgaagag ttacaatatt atttttaaag gtaatcttat ctttagctgt taatgttcgt
     3121 aattcttttt caccaaaaat attaatataa attgcttttt cttctggttt tacatcactt
     3181 gtttttatta ttcccccatc aatataattg aattgttcct tgcatacaac atgatatgac
     3241 tttactatag caaaaatatt cacatgatca ccaacattaa acattctttc ctgtgaagga
     3301 gaaagattac tagatatgac tttcttaaaa gtgttatcat tccaaactgt agtattttca
     3361 tccgtattaa aaatcaattg cgttccttgt ttggcattta tcgatatatt atttttttca
     3421 ataatttctt tattatatat ttcttttaat cttctattat ctaaaatttc gtctttatca
     3481 tatctaggag catatatgtt ccttggattt ctaacatcat ttgtattgta cgtatctgaa
     3541 aagacactct cagtagtgca tagggtaagc gatacacaca caaggaatag caaagccaag
     3601 gtattttttt tcattttttc tcctaatatt ttttaaattt aatcaattta cttagcaagt
     3661 atactatatt taaataataa ttcaactata atttaaaaaa aacaaaaaac cgccctcaat
     3721 caagagagcg gttttgtctt atctcggatc tttacctcct aatttacccc aaagactgat
     3781 aatattcccg tctttgtcag taggaccaat tgccatataa ttacgcttac ctgagcctcc
     3841 gacatagcta atccagtagt agccattggc gtaaccctca ctatcaaagc taacggtttg
     3901 gccttgctta taactatcta ctacctcact ggttaaattc ggccagcggc ggacgttgat
     3961 ctctgcggcg tcaagtgtaa aagtacctga ttttgatgtc tctacgatcg tgtctgaggt
     4021 ttgcgggtct gtgctgaccg tttgtgcagc aacatctccc tgataaggag gataaaacca
     4081 gccggccaca ttagtaaagt cacgagtatt aaaacgggcc ggacccccta catacaacgc
     4141 atctgcatta ccatcaatat tttgctcgat agtctgcata gtgtaaccat ctgagtcaac
     4201 gtacacaaga cccgtatgac cataattgat accaccaaac caagcgtcca tgacaaaaaa
     4261 tgccccagct cgtggatttg catctgtagg catgcgatgg acttcccagc cctgcgcact
     4321 tgcgctatct agtaagtccg ctgcgttgcc ccagagatcg acaccaaacc agtgcttagc
     4381 tgcgtaacaa gggacatctg cacattgcgt gccataagcc ccgtccttat caacacccat
     4441 accagcatta gccaaattga tgtaaaactc gataacctct cgacactgcg aactaatcat
     4501 ttgtgactcc tttctttttg ctagggcttc cgcgtcccat ttttgtaggt cgttttgctc
     4561 tattagttgg ataagcagct ctgcataatc acttgcagtg gcataaccag ctgcttttat
     4621 tgcatgacaa gcctttttat agtcggtctc cccgataact gatttgtatc gtggattatc
     4681 cactaaaaac tggccatgat caaggattga ctcgtcccaa ctgtcatagg ctctaaagcg
     4741 gtccacgaga tccgtcacga cacctggctg atactcctct tgtgtcttgg tatcaaaaga
     4801 tttaccagac catgagctat ctgccttgat accaaacaat gcgttatgtg gggcatactt
     4861 gccccaaccg ctctctaaaa tagcttgagc agccgtcaga gatggcaaaa tcttatgatt
     4921 gtgccactct gcgataactg cgctttttat gtcgtctaaa aaggtcatct gtcctcctca
     4981 cctaaaaacg gataaaagat aagagcaatc acagatagcg gtaaatatag tattgcgatt
     5041 gctaggacta ttgct
//
LOCUS       DARYMD010000082         5030 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.083, whole genome shotgun sequence.
ACCESSION   DARYMD010000082 DARYMD010000000
VERSION     DARYMD010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5030
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..403
                     /locus_tag="TU818_001847"
     CDS             <1..403
                     /locus_tag="TU818_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HEL0924626.1"
                     /translation="DKHNKPYIENKSGVKFNISHTDGFVVIGFSKKELGIDIEKVNDG
                     FAFEDILENCFTSREIKNIGSNIPMFYRYWTAKEAYLKYEGYGLIRNPKEIEVIYIDN
                     QRIKIEDKVKRSNKDLIAFSISSKYFGAICI"
     gene            412..1995
                     /locus_tag="TU818_001848"
     CDS             412..1995
                     /locus_tag="TU818_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL0924627.1"
                     /translation="MNIELKENLEKNYDDNVWEHVTLGEFVANCAETYKDKTAIVDGE
                     LNLSYDELDKLSNKYANGLLKAGFKKGDKIVLQLPNCYEFIVISFAMFKTGIIPIMSL
                     PAHRKNELKGIIEKSEAVAYISKDKYLGFSYVDMVRDMKSELNTNLEIYILGESEEYK
                     NFSSLIENDCFYKYPDVDYRSIGLLLLSGGTTGIPKLIPRRHCDYIYVAKKTTDRCNV
                     NQESVYLASLPIAHNFPLGCPGIMGTFAKGGKVVLCNVTSPDEILPLIEEEKVTITGF
                     VPAIANICMDYLEYEEYDLSSLEVIQVGGSVLEPWLAEKIEKVFDVKLQQIFGIAEGL
                     ILTTNEEDNDKIRWQTQGKPISEHDEILIVDEQGKIVGIEEYGELIVRGPYTIYGYYN
                     LPEVNETCITQDCYFKTGDKARKLKDGNYQIVGRIKEIINRAGEKITPLELEEILLTH
                     ENINSVQVVGLPDRLQGESIAVFILNGDKELTLEEVRKFLISNNVADFKLPDTVKYID
                     AWPLTALGKIDRNKLKETF"
     gene            2010..>5030
                     /locus_tag="TU818_001849"
     CDS             2010..>5030
                     /locus_tag="TU818_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HEL0924628.1"
                     /translation="MELNNIKERAKELVKDWLKSIFVEKVVSENENLIEKGLSSIQVM
                     QLSGKLKKTGIKISFAKLMEEPNLSKWYELIDKSRVKSDKNIESSIIQSDESKFDLTD
                     VQYSYLIGREDDQILGGVGCHAYLEIDGENIDEDKLKEAWNKLQYRHPMLRTKFTKDG
                     KQEILYKPYSEEIEVFDLSDLDEETLHLKLVEIREQKSHRKLNVNQGQVAGVALAKFS
                     DEKSRIFFDVDLLVSDVMSMSIMIKELAELYSGVELDNLNEYTFKDYMQNGIGESIND
                     ADKEFWEQKINSFEIERPNLPLRKQPEQIKETKFTRRKRIIKKSEWETIKDIAASYRS
                     TPSMVLLTAYALVLERWCNQDKFFINIPLFNRDLENENLKEMVADFTNILLVEHEAVD
                     DSNFLDNLKRINKTFLENVSHSEYNGVQVQRDISKKQGTSVYIAPVVFACNIDYPLET
                     EFSRKNLGKVSYMISQTPGVWLDFQTYIVDGDLILCWDSVDELFPTGMLEDMMDSLYE
                     LIISLTQKEEWEKKVDVLPEKQKSIRMQDVEGILPLQYPSETLYDGFLRNVKLNPDRV
                     AIIDSETKEEITYHKLYEISLKVADCLGKNGVKKGDYVGITLPRGSRQLYAIFGILFT
                     GAAYVSIGIAQPNDRRTKIYDQIGIKCIISDEKTVIDCKLNKNEVKIIDLDVAMANVA
                     KLKQPVEISPYDSAYIIMTSGTTGVPKGVEIMHTSAVNTCIDLNEKYNVNAEDTILMV
                     SAIDFDLSVYDIFGILHAGGTVITTSEDNYRNPDEWLNLVDEYKVTIWDSVPILFDMI
                     VTMAEGKNRNLPFRIVMLSGDWIAINLPERFYNISENINSIVVAMGGATEASIWSNHL
                     NVPRKIPKDWISIPYGRPLKNQVYRVVDEFGRICPNYVKGELLIGGVGVAKCYHGDEE
                     LTNKKYFEQDGMRWYRTGDNGRTWNDGIIEFLGRKDTQVKVKGHRIELGEIENALIVF
                     ENIKKAIALIVKDGNVNKLVGFAEIFDCKESNQML"
BASE COUNT         1887 a          552 c         1067 g         1524 t
ORIGIN      
        1 agataagcat aataaaccat atattgaaaa taaaagtgga gtgaaattta atatttcaca
       61 tacggatgga tttgtagtaa ttggtttttc aaagaaagag cttggaatag acattgaaaa
      121 agtgaatgat ggctttgcgt ttgaagatat acttgaaaat tgctttacat ccagagagat
      181 taagaatata ggcagtaata taccaatgtt ttatagatat tggacagcaa aagaagccta
      241 cctaaaatat gaaggatatg gtcttataag aaatccgaaa gaaatagaag ttatttatat
      301 cgacaatcag agaataaaaa ttgaagataa ggtaaaaagg agtaataaag atttgatagc
      361 attcagcatt tcatcgaaat attttggagc aatttgcata taggaggaag tatgaatata
      421 gaattgaaag aaaatttaga aaaaaattat gatgacaatg tttgggaaca tgtgaccttg
      481 ggagagtttg ttgcgaactg tgcggaaacg tataaagata aaacagcgat tgtagatgga
      541 gaattaaact tatcttatga tgagcttgat aaactttcga ataagtatgc taatggacta
      601 cttaaagcag gttttaaaaa aggagataag attgtattac agcttccaaa ttgttatgaa
      661 tttatagtga tatcttttgc aatgtttaaa acaggaatta ttccgattat gagtttgcct
      721 gcacatcgaa agaatgaatt aaagggtatt atagaaaagt ctgaggcggt agcatatatt
      781 tcaaaggata aatatttagg tttttcatat gtggatatgg ttcgggatat gaaatctgaa
      841 ttaaatacga acttggagat ttatattctt ggagaaagtg aagaatataa aaatttttcg
      901 tcacttattg agaatgattg tttctataaa tatccggatg tcgattacag gagcatagga
      961 ttattgttat tatctggcgg tacaacagga ataccgaaac tgattccaag aagacattgc
     1021 gattatatct atgttgcaaa gaaaacgacg gaccggtgta acgtaaatca ggaaagtgta
     1081 tatcttgctt ctttgccaat agctcataat tttcctttgg ggtgtccagg gataatgggt
     1141 acttttgcaa aaggcggaaa ggtggttttg tgcaatgtga caagccctga tgaaatttta
     1201 cctttaattg aggaagaaaa ggttacgata acaggatttg ttcctgcaat tgccaatatt
     1261 tgtatggatt atttagagta tgaagagtat gatctttcct ctttggaggt tatacaagtc
     1321 ggaggttcag ttttggaacc ttggttggca gaaaaaattg aaaaagtttt tgatgttaaa
     1381 ctacaacaga ttttcggaat cgctgaagga ttgatcttga caacaaatga agaagataac
     1441 gataaaataa gatggcaaac acaaggcaaa ccaatcagtg aacatgatga aatactgatt
     1501 gtggatgaac aaggaaaaat tgtagggatt gaagaatatg gagaacttat cgttagaggt
     1561 ccttatacca tttatggtta ttataatctt cctgaagtaa atgaaacatg tataacacaa
     1621 gattgttatt ttaagactgg tgataaagca cgaaaactaa aagatggtaa ttatcaaatt
     1681 gtcggaagga tcaaagaaat catcaataga gcaggtgaaa agataacacc acttgaatta
     1741 gaagaaattt tgcttactca tgaaaatatc aactcggtac aagttgtagg gctgccagat
     1801 cgtctgcaag gagaatccat tgctgtattt attttaaatg gagataagga gcttacactg
     1861 gaagaagtta gaaaattctt gatttctaat aatgtggcgg attttaaatt gccggatact
     1921 gttaaatata ttgatgcgtg gccattaaca gctttaggga aaatagatag aaataaatta
     1981 aaagaaactt tttaaaggag gattttggaa tggaacttaa caatataaaa gaaagagcta
     2041 aagaattagt aaaggattgg ttgaaaagta tatttgtaga gaaagtagtt tcagaaaatg
     2101 aaaatttaat tgaaaaaggt ttaagttcca ttcaagtcat gcaactgtct ggaaaattaa
     2161 agaaaacggg gataaaaatt tcgtttgcaa aacttatgga agaaccgaat ttgtccaagt
     2221 ggtatgaact tattgataaa tccagagtga aaagtgataa gaatatagag tcatcaatta
     2281 tccaaagtga tgaaagtaag tttgatttaa cagatgtcca gtactcctat ttaatcggaa
     2341 gagaagatga tcagatttta ggtggcgtgg gttgccatgc atatcttgaa atagatggag
     2401 aaaatattga tgaggataag ttaaaagagg cttggaataa gcttcaatac agacatccca
     2461 tgcttagaac aaaatttacg aaagacggga agcaggaaat attatacaaa ccgtacagtg
     2521 aagaaataga agtttttgat ttatctgatc ttgatgaaga aacgctgcat ctaaaattag
     2581 tagaaattag agaacaaaaa tctcatagga aattaaatgt aaatcaaggt caggttgcag
     2641 gagtagcact agcaaaattt tcagatgaga agtcaaggat attttttgac gtagatttgc
     2701 ttgtatccga tgtaatgagc atgagtatta tgattaaaga attagctgaa ctttattcag
     2761 gagtagaact tgataatttg aatgagtata cgtttaagga ttatatgcaa aacggaattg
     2821 gcgaatcaat caatgatgca gataaggagt tttgggaaca aaaaataaat tcctttgaaa
     2881 tagaaagacc gaatttacca ttaaggaaac agccggaaca aattaaagaa acgaagttta
     2941 caagaagaaa gagaattatt aaaaaaagtg aatgggaaac cataaaagat atagcagcat
     3001 cgtatcgaag tacaccatct atggttcttc taactgccta tgctcttgtt cttgaaagat
     3061 ggtgtaatca ggataaattt tttatcaata taccgctatt taatagagat ttagaaaatg
     3121 aaaatctaaa agaaatggtt gctgatttta caaatatttt attggtagag catgaggctg
     3181 tagatgattc aaatttttta gataatttaa agagaataaa taagacattc ttggaaaatg
     3241 tatctcacag tgagtataac ggagtgcagg ttcaaagaga tatatcaaaa aaacaaggta
     3301 caagtgtgta tatagcacct gtggtttttg cgtgtaatat agattatcca ttggaaactg
     3361 aattttcaag aaaaaattta gggaaagtat cttatatgat ttctcaaaca ccaggagttt
     3421 ggcttgattt tcaaacatat attgtagatg gagatttaat tctttgctgg gatagcgtgg
     3481 atgaactttt tccaacagga atgttagaag acatgatgga ttctttatat gaattgatca
     3541 tatctttaac acagaaggaa gaatgggaaa agaaagtaga tgttttacct gaaaagcaaa
     3601 agtctattag aatgcaggat gttgagggaa ttttaccact tcaatatcct agcgaaacgt
     3661 tatatgacgg atttctcaga aatgtaaaac tcaatccaga tagagttgcg attatagatt
     3721 ctgaaacgaa ggaagagata acatatcata aactttatga aatctcttta aaagttgcgg
     3781 attgtttagg taaaaatggt gttaaaaagg gagattatgt aggaataaca cttccaagag
     3841 gtagcagaca actttatgct atttttggga ttttatttac cggtgcagca tatgtatcaa
     3901 ttggtattgc tcagccaaat gatagaagaa ctaaaattta tgatcaaatc ggaataaagt
     3961 gcattataag tgatgaaaag acagtgatag attgtaaatt aaataaaaat gaagttaaaa
     4021 ttattgattt ggatgtagct atggcaaatg tggctaaatt aaagcaacct gttgaaatta
     4081 gcccttatga tagtgcgtat attattatga cgtctggaac aacaggtgtt cctaagggtg
     4141 ttgagattat gcatacaagt gccgttaata cttgcattga tttaaatgaa aaatacaatg
     4201 taaatgctga agatacaata ctgatggtgt cggcaataga ctttgatttg tcggtttatg
     4261 atatttttgg aatacttcat gctggaggaa cggttattac aacaagtgaa gataattata
     4321 gaaatcctga tgaatggtta aatttagtcg atgaatataa ggttacaata tgggattctg
     4381 tgccgatttt gtttgatatg attgttacta tggctgaagg taaaaataga aacttacctt
     4441 ttagaattgt gatgctttca ggggattgga ttgctataaa tttaccagaa agattctata
     4501 atattagtga aaatataaat tctattgttg tcgctatggg tggagccaca gaagcatcta
     4561 tttggtcaaa ccatttgaat gtaccaagaa aaataccgaa agattggatt tccattccat
     4621 atggtagacc tttgaaaaat caagtgtata gagttgtgga tgaatttggt aggatctgcc
     4681 ctaattatgt taaaggtgaa cttcttatcg gtggagttgg tgttgctaaa tgttatcatg
     4741 gtgacgaaga attaacgaat aaaaagtact tcgaacaaga tgggatgagg tggtatagaa
     4801 ctggagataa tggtagaaca tggaatgatg ggattattga gtttcttgga agaaaagata
     4861 ctcaggtaaa agttaaagga catagaatag aacttggaga aatagagaat gctttaattg
     4921 tatttgaaaa tataaaaaaa gcgatcgctt taattgttaa agatggaaat gttaataaac
     4981 ttgtaggatt tgcggaaata tttgattgca aagaaagtaa tcaaatgtta
//
LOCUS       DARYMD010000083         4866 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYMD010000083 DARYMD010000000
VERSION     DARYMD010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4866
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            77..805
                     /locus_tag="TU818_001850"
     CDS             77..805
                     /locus_tag="TU818_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0924629.1"
                     /translation="MIKEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRI
                     TIRLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILS
                     FEKIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEAITIDLLEK
                     KPLYDVFAEDFQEAIRLADEEFYASIALDYEAKLLGIKKGDPVLHIMRKTYNEKNRLI
                     EFTFSIARADQFRYRIQHHPNKKI"
     gene            817..1992
                     /locus_tag="TU818_001851"
     CDS             817..1992
                     /locus_tag="TU818_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL0924630.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWSEVFESFLKQKKDLLA
                     FFDRIIESANRNKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLYYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     KRSYLFLLPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLEEKKCYLDQIVGMVAAII
                     QQEADLQKLVSLEFQRLVYLGSGALAGLTQEAQLKILELTAGKIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFGL
                     DSSMLLPDAYLAFPLVFIAQTLALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            2002..2997
                     /gene="lacD"
                     /locus_tag="TU818_001852"
     CDS             2002..2997
                     /gene="lacD"
                     /locus_tag="TU818_001852"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL0924631.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGVLKRMMAAHQDTEP
                     TPWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDERINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSTERFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEEAARQWLRTEGFENIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(3039..3758)
                     /locus_tag="TU818_001853"
     CDS             complement(3039..3758)
                     /locus_tag="TU818_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0924632.1"
                     /translation="MTIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLGTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDFHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            3898..>4866
                     /locus_tag="TU818_001854"
     CDS             3898..>4866
                     /locus_tag="TU818_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL0924633.1"
                     /translation="MKQFCIKEQFYLDGKPFNILSGAIHYFRIAPDSWSRVLYQLKAL
                     GFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLAQECGLYAIVRPSPYICAEWEFG
                     GLPAWLLTENCRLRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
                     GEEKAYLRKLKELMLAKGISAPLFTSDGPWPATLASGSLIDDDVFVTGNFGSNASKQF
                     ASMQDFFQAHQKQWPLMCMEFWLGWFNRWNEPIIRRDSKEAVDAIMEAIELGSINLYM
                     FCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYTLLQ"
BASE COUNT         1376 a          871 c         1189 g         1430 t
ORIGIN      
        1 tttttcaaaa aagtattgac ttttagattg taatataata ttatttaagt ggttataata
       61 agttagaggt gttagtatga taaaggaaca gccactctac ttacaaattg ttgatgtatt
      121 agaggtcaaa attagaaata ccatgtcagc taatgataaa ttgttatcag aacgagagct
      181 aagtgactta tttggtgtta gtcggataac cattagattg gcacttaagg agctagagct
      241 gcgtgggctt atttacaaac agcagggcaa ggggacctat gtatcaggca taaaggagcc
      301 tgctacagac ctgtcctcag cctatagctt taccgaagag atgaaaaagc aaggtcgtaa
      361 gcctcaaaca gtcattcttt catttgaaaa aatcaagacc acagcttact tgtctggtat
      421 gttagattta gatgttgata ctgatgtttt tgagctagag cgtctaagga ttgcagatgg
      481 aaagccatta atgtttgagc gcacttatat acctgaaagg ggatttgagg cgataacgat
      541 tgatttattg gaaaaaaagc ccttatatga tgtgtttgct gaggattttc aggaagctat
      601 ccgattggct gatgaggagt tttacgctag tatcgctcta gattatgaag caaagctatt
      661 agggatcaaa aagggggatc ctgtgctgca tattatgcgt aagacctata atgagaaaaa
      721 taggctaatc gaatttacct ttagtattgc tagagcagac cagtttaggt accgtatcca
      781 gcaccaccct aacaagaaga tataggaggt aaggaaatgt ttacaaaaac acaagcagaa
      841 ctagagctac ttggcgcagc tatcaccact agagaaatca agcagcagcc agagctatgg
      901 tcagaggtct ttgagtcttt tctgaagcaa aaaaaagacc tcttagcctt ttttgacagg
      961 attattgaaa gcgctaacag aaacaaggta aaaattattt ttacaggagc tggaacttct
     1021 gaatacattg gcaataccat ttgtcattat ttggagatga ctggtgacag ggaaaattat
     1081 ttatattaca gcattgcttc cacagacctt gttgcagctc caagccagta tctctttgaa
     1141 gaggatacag tcgtgcttgt ttcctttgca agaagtggca atagtcctga aagtgtcgct
     1201 gctgttagtc ttgttaatca gctggtgtca aatccttatc atttggtgat aacctgtgcc
     1261 aaagaggggg ccttagctca aaatgctaag aaggacaaaa ggagctattt attcttgctg
     1321 cctgaggcct caaatgacgc tggctttgct atgacgggaa gctttagctg catgatgcta
     1381 gcggccttgt tgatttttga tcaagcgcat tcccttgagg agaaaaaatg ctatttagat
     1441 cagattgtag gtatggtggc agctattatt cagcaggagg ctgatttaca aaagctggtt
     1501 agcttagagt ttcaacgctt ggtttacctg ggatcaggag ccttagcggg gcttacgcaa
     1561 gaggctcaat tgaagatttt agaattaaca gctggcaaaa ttgcaacagt ctatgactcc
     1621 tcaatgggct ttaggcatgg tccaaagtca tttattgatg atcagacatt ggttattggt
     1681 tttgttagca atgatcctta tacgagaagg tatgaccttg atgttttaga agagataaga
     1741 gaggatgcta ttgctgttga tacggttgca ttacagcagc aaggaggtga gggctttagt
     1801 gggcattgct ttggcttaga ctcgtcaatg ctattgccag atgcttattt ggcctttccg
     1861 cttgttttta tcgcccaaac gcttgctttg ctgtcgtcta ttaaggttaa taatttacca
     1921 gatactcctt cggccacagg aacggttaac agggttgtcc aaggtgttaa gatttatcac
     1981 tattttaagt aggagaacaa gatgtaccat ttatcaaaag ctaagtatcg tcttcttgaa
     2041 aaggtcagtc gtaagggcat catttcggcc ttggcctttg atcaacgcgg ggttttaaag
     2101 cgcatgatgg cagcccacca agacacagag ccaactcctt ggcaaatcga agccctaaag
     2161 gctctggtat cagaggagct aaccccctat gcctcctcta tcctgctaga ccctgaatat
     2221 ggcctgccag ccaccaaggt gcgtgatgag aagtctggct tattattagc ctatgaacaa
     2281 accggctatg acacaaccac cactagccgc ctgccagatt gtctggtgga ctggtcagtc
     2341 aagcgcctca aggaggccgg agctgacgca gtgaagttct tgctgtacta tgatgttgat
     2401 ggtgatgagc gtattaacca acaaaagcag gcctatatcg agcgtatcgg ctcagaatgt
     2461 caggcagagg agataccatt tttccttgag ctattgacct atgatgaggc gataacagac
     2521 aatcagagtg tagcttttgc caagctaaag gcacacaagg ttaatgaggc catgaaggtc
     2581 ttttcaactg agcgctttgg ggttgatgtc ctaaaggtag aggttcctgt caatatggcc
     2641 tatgttgagg gctttgcaga gggtgaggtt gtttacagca aagaggaggc tatgcaggcc
     2701 tttcgtgacc aagaggcagc tagtcacttg ccctatattt atttgagtgc gggtgtatca
     2761 gctagtctgt ttcaagagac cttggttttt gcggcagagg caggagctag gttcaatggt
     2821 gtgctgtgtg gtagggccac ttggtcagga gcagtagcgg tgtacatgtc agagggcgag
     2881 gaggcagcgc gtcaatggct tcgcacagag ggttttgaaa atattgatcg tctcaatcag
     2941 gtgcttgaga aaacagccag cccttggaca acaaagctta ctcttgatga agcctagtaa
     3001 aggcatgata aaagcaatac taggacattg cttctgtatt attggtaatc actggaggac
     3061 aaggcgtact tgaaaaattg ccaatgcttg taggactcgg tgtactctag aatacggcca
     3121 ttatctgtcg accgagtgag cttggtttga aggacacaag gagtgttgtc tatcatgttt
     3181 aaaaatgtag cgacatcttt aggcatgtga tccgtcagct gtgtttgctg ggtgaagctt
     3241 tgtgatcgca tttgaatgtg aaaatccaaa aagaagcgct tataaagcga ctggtaatca
     3301 gctaaatcac gctcagggca cagcaggtaa tcatgaggaa tataagatag ctggtataaa
     3361 tagggctgct gattaatcgt tcgtgtacgg gagatggtgt agtaaaattc cgttttatga
     3421 agtttcaaga gatttagata gtagggatca tttcccttaa ctacactaag gacagtcacc
     3481 tcctcttttt gatccttaaa ggtacctaga taggaaaatt ggactagctg ttcttttctg
     3541 gtacgggtaa tgaaggttcc aagtccctgc cttcttctga taaagccttc tttttctagt
     3601 tctttaaggg ctcgaatgat ggttatggag ctaacatgaa agcgtttaat cagctcggct
     3661 tcggtataaa atttgtcccc ggtatggtag tggccattca gaatttggtt ttgcaattct
     3721 tctttgatta gtcggtactt tgggtatttg atggtcatag ttactcactc aataattgtt
     3781 tagtacgatt atagcaaaaa tagtaagctg atgtcatatc ttaccagtta ttgctcagat
     3841 agcttgtcaa tcagtcattg atcaaaggct gatggttaat gaataaaagg agataatatg
     3901 aagcaatttt gcataaagga gcagttttac cttgatggca agccgtttaa tatattatca
     3961 ggtgccattc attactttag aatagctcct gatagctggt ctagggtgct ttatcagctg
     4021 aaggccttag gctttaatac agtagaaacc tatattcctt ggaatatgca tgagccaagg
     4081 aagggacagt ttacctttga ggggattgca gatgttgagg catttttgga tttggcacag
     4141 gaatgtggcc tatatgctat tgtcagaccc tctccttata tctgtgctga atgggagttt
     4201 ggtggtttac cggcttggct attaactgaa aattgtaggc tcagatcaag cgatgaggtc
     4261 tttcttaagc atgtatcaga ttattatgat gtgttactac caaagctggt gaagcgtcag
     4321 ttagataatg gcggcaatat tctgatgttt cagcttgaaa atgagtatgg ttcttatggt
     4381 gaagaaaagg cttatttaag aaaattaaaa gagcttatgc ttgctaaagg cattagtgcc
     4441 cctctcttta cctcagatgg gccttggcca gccacgctag catcagggag tctgattgac
     4501 gatgatgttt ttgtgacagg caactttggg tcaaacgctt caaagcaatt tgccagtatg
     4561 caggattttt tccaagcaca tcaaaagcaa tggcctctga tgtgtatgga attctggttg
     4621 ggctggttta atcgctggaa tgagccaatc attcgaaggg actccaagga agctgttgat
     4681 gcaatcatgg aagctataga gctaggcagc attaaccttt atatgttttg tggtggcact
     4741 aattttggct ttatgaatgg ctcgtcagct cgtctgcaaa aggatttacc acagataacc
     4801 tcctatgatt acgacgcatt actagatgag gcagggaacc cgacaaagaa atataccctg
     4861 ctgcaa
//
LOCUS       DARYMD010000084         4192 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYMD010000084 DARYMD010000000
VERSION     DARYMD010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4192
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(44..754)
                     /locus_tag="TU818_001855"
     CDS             complement(44..754)
                     /locus_tag="TU818_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL0924634.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDIVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
     gene            complement(1201..2559)
                     /locus_tag="TU818_001856"
     CDS             complement(1201..2559)
                     /locus_tag="TU818_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL0924635.1"
                     /translation="MILKSGIRNNHIKWIFTMLPLFVSVLPFISNIEKVFILILISIF
                     LLASNIIPAWYTSILFMTACMIGNIAEKQVILSGITSGAAWLVISGVIIGAAVKHTEL
                     DRLLARFFIPVCMGKYSKVLFGTILLGVVLIFLMPSAMGRVVLLLPILNALSLELGYE
                     KGSKEWEGIVMSGVLATYIPAFYVLPSNVPNNVFTGAILSLYSINISYSRYFLLYFPI
                     LGVGKILILYFTMRLFYRRCKDSICVSKKAIDITKEQKLLIVLLFITLSFWMTEHIHK
                     VPTGWTGMATALIVMLPNSNFMEKQPLRKINFEPFFYVAGIISLGNIAKSSGLANVIA
                     VHLINIVSLETASAFNVLTFFVVLCIILGFIVTLPGVPAVVTPLIDNISGVSNVSKTF
                     LCHIEVIGFSSVFFPFQAPPLMVVLQNENLSKARMTIYCSIVSAIGLLLLLPLALYWK
                     ML"
     gene            complement(2967..3197)
                     /locus_tag="TU818_001857"
     CDS             complement(2967..3197)
                     /locus_tag="TU818_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924636.1"
                     /translation="MKNIDEKILMTDGEIKQLQNKRKKPIIQSKQEERKKRDRRLYEK
                     GAVNQKILKIIEKREQTEENIEVQEEATDTEE"
     gene            complement(3291..3704)
                     /locus_tag="TU818_001858"
     CDS             complement(3291..3704)
                     /locus_tag="TU818_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924637.1"
                     /translation="MARKLAIIVIATGILFALIACILFFKKDILQVFPRMDIAWVGFL
                     VVAILLCVSGIWVFSISGKKQDWINETDERESLITAKANMVGYVIQTTLLGIVFFLLV
                     FMGYLNKVSGFSIIGVVLISGIVSWIYHLYLRKVE"
     gene            complement(3739..3936)
                     /locus_tag="TU818_001859"
     CDS             complement(3739..3936)
                     /locus_tag="TU818_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0924638.1"
                     /translation="MKNRLEEIRKENGITQEELASILEVSRQTIGSLENGRYNPSIIL
                     AFKIAKYFSLSIEDIFIYEEE"
BASE COUNT         1315 a          808 c          562 g         1507 t
ORIGIN      
        1 gctagaactc aagccttgga gtgctaagtc atttttctat tctttagtag cccattcgtt
       61 gtgcccatgc cttatcaata gcaagggttt cagtgtctgt atagctcttg cgataaggat
      121 tccagacaga ggtcaaagga gccgcagcaa gcgcttcttg cgcctgatta tttactatat
      181 cataggccgt tagaccgtag gtctcaatga tgttgtttaa tttccagtta tagctagtat
      241 ctgtagcata caagcctgtt aaagctgctg tagcgtcctg ataagacaag gtatttgact
      301 ttctagcacc tgcataaata tctgagctaa gcaaattagt gtaatcatat aaggaatcag
      361 ccactgtcgg ataagctcta aaggtttgat cgatgtagta agtatttcca gccccatcgt
      421 cttcccatgt tgtcatcgtc actgatgacc cattataagc ccctttaatg ccaaaaaaat
      481 tataataagg tgcttgactt aaagctgatt taccgttagc tgactctaaa atagcttgag
      541 caatcataac cgaagcatac aagtctcttt cttgagcaac aacactagca gttgctccaa
      601 tctcttcaat aaaggcttgc gttgacgacg ttgacacagt ctctgctgag acatctgatg
      661 tattttctga ctgtctaatt gaactataaa cacctaagca ggctactaga acaaaaagac
      721 tgataagtgt gagcttacct ttcttttttg ccatttatca ttccctcttt ttttgataaa
      781 tagattatag cacagaatgc tcataaaaag acttatccac aaacaattta atcatattga
      841 taacttttgt ctttaaatcg aaatatttta atgtaaagaa ggcttaccaa gtccataaag
      901 cgaaggcttt tcataatctt ttacgcctta tttgctatat cgccttgtaa tagcttcaat
      961 acctttgaaa ggttattaca cctactattg ttctttatgc ctgtctgtta agtattttcc
     1021 atttaactgc ctttattttt taggtaaaga aaaaacagta aaccattaat ttactgtttc
     1081 ttaattgata tttaatattt tcttataact attgatgtta aataaatgaa aatatatcat
     1141 tcttgtttac taccaacttc taactagtat agtacgagga tataattaaa tcttcgtctt
     1201 ttacaacatt ttccaatata acgctagtgg taacaacaat aataatccaa tagctgatac
     1261 aatcgaacaa tatattgtca ttcttgcttt tgataaattt tcattttgta aaaccaccat
     1321 caagggtggt gcctgaaatg ggaaaaatac acttgaaaaa cctataactt caatatgaca
     1381 taaaaatgtt tttgaaacat tactaacgcc tgaaatatta tcaatcaaag gtgtaactac
     1441 tgccggaaca cccggtaaag ttactataaa tcctaatata atacacaata caacgaaaaa
     1501 agttaaaaca ttaaatgcac ttgctgtttc caaagaaaca atattgatta aatgcacagc
     1561 aatgacattt gcaagtcctg aagattttgc tatattccct aaacttatga ttccagctac
     1621 ataaaaaaat ggctcaaaat ttatttttct taaaggttgc ttttccataa aatttgaatt
     1681 tggtaacatt acaatcaagg cagttgccat tcctgtccaa ccggttggta ctttatgaat
     1741 atgttctgtc atccagaaag acagagttat aaataacaaa actattaaca atttctgctc
     1801 ttttgttatg tcaatggctt ttttggacac gcaaatcgaa tctttacatc ttctataaaa
     1861 taaccgcatt gtaaaatata aaatcaatat ttttccaact cctaaaatag ggaagtacaa
     1921 gagaaagtat ctgctatagg atatatttat ggagtaaaga cttaaaattg ctccagtaaa
     1981 aacattattt ggaacattgg aaggtaatac ataaaatgca ggtatatagg ttgctaaaac
     2041 ccctgacata acaattcctt cccattcctt acttcctttt tcataaccta attctaaaga
     2101 tagggcattt agaataggta aaagcaaaac tactctaccc attgctgatg gcatcaaaaa
     2161 aattagtacc actcctagca aaatcgtccc aaataacact ttagaatatt tccccatgca
     2221 caccggaata aaaaatctcg caagtaatct atcaagttca gtatgcttta ctgccgcccc
     2281 tataataaca cctgaaataa caagccatgc tgcacctgaa gttatccctg ataagatgac
     2341 ttgcttctca gctatattcc ctatcataca agctgtcata aataaaatgc ttgtatacca
     2401 tgcaggaatt atattgcttg ccaaaaggaa gatagatata agaatcaaaa taaaaacttt
     2461 ctctatattt gaaataaatg gtagtacaga tacaaacaac ggtaacattg taaatatcca
     2521 ctttatatga ttattcctaa ttccagattt taaaatcatc ctccattttt gacctccaac
     2581 tctaatttat ttcatagtat tataccatat ttattttcat tttataggtc tacctcttgc
     2641 ttctttgtct gtgttaatcg cttttcttgt ttttataact gctctataca agtcttaact
     2701 ttttctgcct gtttaatttt ttctcgtatc tctaatattt tattgtgtaa gctctttttt
     2761 tctttcttca tattggcgac ttccgatttt catttgctaa tgactaaggt cttgctttcg
     2821 cccaaatgct cttttagata tttcttggca ctctcaaata aaataatctc tgctgtatca
     2881 acgttagctg atatgccctc tgcaagagcc ttcggagaac gcacgcacct gttgaggtgt
     2941 atatgtacac tcttgtaaac aagggactat tcctctgtgt ccgttgcttc ctcttgcact
     3001 tctatgtttt cttctgtttg ttctcttttc tctatgattt ttaggatttt ttgattgact
     3061 gctccctttt cataaaggcg tctatctctc ttttttctct cttcctgttt cgactgaatg
     3121 atgggctttt ttcttttgtt ttgtaactgc ttgatttctc catctgtcat taaaattttt
     3181 tcatctatgt ttttcatttt ctattttcct ctctttctgt tttgagcaac aaaaaaacag
     3241 taaaccattt ttttgattta ctgttttcta ataaatatta tcttagttat ctattctact
     3301 tttcgtaaat ataaatgata aatccatgat acgataccac ttatcaaaac aactccaatt
     3361 atagaaaacc cagaaacttt gtttaaatag cccataaaaa ctagaagaaa aaaaactatt
     3421 cccagtaaag ttgtttgaat cacatatcct accatattag ccttagctgt tattaaggac
     3481 tctctttcat cggtttcatt tatccaatct tgttttttac ctgaaattga aaatacccat
     3541 attccactaa cacacagaag aatagcaaca acgagaaagc ctacccatgc aatatccatt
     3601 cttggaaata cctgtaaaat atctttttta aaaaataata tgcaagcaat caaggcaaaa
     3661 agtattccag tagcaataac tataatagct aactttcttg ccataaccat ctcttttttt
     3721 atatttcttt tcattttttt attcctcctc gtatataaag atatcttcaa tgcttaaact
     3781 aaaatactta gcaattttaa aagctaaaat aatggaagga ttataccttc cgttttctaa
     3841 agaaccaatt gtctgccttg atacttcaag aatagatgct aactcttcct gtgttattcc
     3901 attttctttt ctgatttcct caagtctatt tttcacattt aatgacctcc tgcaacaatg
     3961 acaagctaac tttacatata gtataatgtt ttttagagaa aatggcaagt atactttcca
     4021 taaaatcgtt tccttatagg tctagccctt acttttttac atgtacgact cctctatatc
     4081 tgcattttcc tcttatactt ctgtctgttg atgagcactt gcttctcttt gtgatgatat
     4141 ctttactatg cttttcattt ttgggatttt tatcttaatt ttgagtagtc at
//
LOCUS       DARYMD010000085         3667 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYMD010000085 DARYMD010000000
VERSION     DARYMD010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3667
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            11..81
                     /locus_tag="TU818_001860"
     tRNA            11..81
                     /locus_tag="TU818_001860"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Gly,seq:tcc)
     gene            111..184
                     /locus_tag="TU818_001861"
     tRNA            111..184
                     /locus_tag="TU818_001861"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:145..147,aa:Ile,seq:gat)
     gene            197..268
                     /locus_tag="TU818_001862"
     tRNA            197..268
                     /locus_tag="TU818_001862"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:230..232,aa:Glu,seq:ttc)
     gene            279..368
                     /locus_tag="TU818_001863"
     tRNA            279..368
                     /locus_tag="TU818_001863"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:315..317,aa:Ser,seq:tga)
     gene            380..453
                     /locus_tag="TU818_001864"
     tRNA            380..453
                     /locus_tag="TU818_001864"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:414..416,aa:Met,seq:cat)
     gene            478..550
                     /locus_tag="TU818_001865"
     tRNA            478..550
                     /locus_tag="TU818_001865"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:511..513,aa:Phe,seq:gaa)
     gene            570..650
                     /locus_tag="TU818_001866"
     tRNA            570..650
                     /locus_tag="TU818_001866"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:604..606,aa:Tyr,seq:gta)
     gene            657..727
                     /locus_tag="TU818_001867"
     tRNA            657..727
                     /locus_tag="TU818_001867"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:689..691,aa:Trp,seq:cca)
     gene            739..811
                     /locus_tag="TU818_001868"
     tRNA            739..811
                     /locus_tag="TU818_001868"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:772..774,aa:His,seq:gtg)
     gene            820..891
                     /locus_tag="TU818_001869"
     tRNA            820..891
                     /locus_tag="TU818_001869"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:852..854,aa:Gln,seq:ttg)
     gene            910..993
                     /locus_tag="TU818_001870"
     tRNA            910..993
                     /locus_tag="TU818_001870"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:944..946,aa:Leu,seq:caa)
     gene            complement(1337..2467)
                     /locus_tag="TU818_001871"
     CDS             complement(1337..2467)
                     /locus_tag="TU818_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009855141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0924639.1"
                     /translation="MILRKYNDFCRLFLGRLISNCGDSIYTLVLSWYVLETTNSTWYV
                     GLLNFLIFIPNTFSFIFGKKIDSYPKKNLLVILEWAQLLAVLGIILGMSLREIHASLS
                     LTIIFSCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISG
                     FLLSVISYIPLLFINIVTFLGSILFFRRIAFKEIIEQTNERTDFLSGLRFIWHNKVVL
                     AITLGGAIANFLFASLNVYQLLIAREVGNSAFYGLLVSVSAIGTLVGTTFVANLVLQK
                     LSVGKAFWLATTLLGTGIGLTALVPNRFGLLLLWFLSCLFLGITHVTQKPILRTEIPD
                     EHLGEVFSAFYTVTIPTLALGSLILISLLYFSNKMLRQYDIC"
     gene            3033..>3667
                     /locus_tag="TU818_001872"
     CDS             3033..>3667
                     /locus_tag="TU818_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0924640.1"
                     /translation="MTTKEKQTKLMRRYGIFSVVVALTALAGLGAANEVKATAKKSLN
                     ELPNPVEIIQYNSTRTTDREARKYLNQLYEFLKPYLGSLEEEAQKGGPQGPVGPAGPR
                     GERGEPGPKGDRGPEGQRGEQGPAGPIGPQGPRGDKGETGEIGPRGEQGPTGPTGKPG
                     ERGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKG"
BASE COUNT         1123 a          706 c          848 g          990 t
ORIGIN      
        1 tcccatttta gcgggtgtag tttagtggta aaactacagc cttccaagct gttgtcgcga
       61 gttcgattct cgtcacccgc tttatagttt tcccaagcta tagtgtgctt gggcgcgtag
      121 ctcaggtggt tagagcgcac gcctgataag cgtgaggtcg gtggttcgag tccactcgtg
      181 cccattaaga tatgatggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt
      241 aacacgggtt cgaatcccgt acggactata ttgtcattgg aggattaccc aagtccggct
      301 gaagggaacg gtcttgaaaa ccgtcaggcg tgtaacagcg tgcgtgggtt cgaatcccac
      361 atcctccttt aaagattatc gcgggatgga gcagttaggt agctcgtcgg gctcataacc
      421 cgaaggtcgt aggttcaaat cctgctcccg caattatata aaagatatat gctggttggc
      481 tcggtagctc agttggtaga gcaatggatt gaagctccat gtgtcggcgg ttcgattccg
      541 tctcgcgcca tagtaattta atatgttttg gaaagatagc gaagaggcta aacgcggcgg
      601 actgtaaatc cgctccttcg ggttcggggg ttcgaatccc tctctttcca tcctgaacgg
      661 gcatagttta aaggtagaac taaggtctcc aaaaccttca gtgtgggttc gattcctact
      721 gcccgtgttc agaatatggc gggtgtggtg aagtggttaa cacatcagat tgtggctctg
      781 acattcgtgg gttcgattcc catcactcgc ctattttatt ggggtatagc caagcggtaa
      841 ggcaagggac tttgactccc tcatgcgttg gttcgaatcc agctacccca gtttagtttt
      901 atacttaaag ccggcgtggc ggaattggca gacgcgctgg actcaaaatc cagtgtccgc
      961 aaggacgtgc cggttcgacc ccggccgccg gtatagttta aaaatattga aaaaacaagg
     1021 tttgtaaacc ttgttttttt gttttatgac ttgatgtcag aggatcagat tggtcctctc
     1081 tagatgttaa aggtaatgag aatcttggct tcaaagctcc taaatccaaa gcattgcgct
     1141 tgatgtcttt gatcacctgt tagtggcgtg cagcttagcg tttgaatttg gaataaggtt
     1201 gctccaaggc atgtgtgatg tgagctttgg atactaggac ttttagccaa ttctttgtgg
     1261 gtgagctttt tctttacgtt tggttttgat taatgtcgca atatcagtta tcatgtgttc
     1321 tctggttaat gacgctttag caaatatcgt attgtcttag catcttgttt gagaaataaa
     1381 gcagactaat taagataagc gaacccaagg caagtgttgg gatggttacg gtataaaaag
     1441 cactgaaaac ttcaccaaga tgctcatcag gaatctcagt tcgtaaaata ggtttttggg
     1501 taacatgcgt tattccgaga aatagacagg aaagaaacca aagaagcaac aaaccaaaac
     1561 ggttggggac taatgctgta aggccaatac cggtgcccaa aagggtagtt gctagccaaa
     1621 aagcttttcc tacacttaac ttttgcaaga caaggttagc aacaaaggtt gttcctacca
     1681 gggttccgat agcacttaca gatactaaga ggccataaaa agctgaattc cctacctctc
     1741 ttgctattaa taactgatag acatttaagc tggcaaaaag gaaattagcg atagcacctc
     1801 ccaatgtgat ggctaacacc actttattgt gccagataaa gcgcaagcca cttaaaaagt
     1861 ctgttcgttc atttgtttgt tcaattattt ctttaaatgc tattcttcta aaaaatagga
     1921 ttgaacctaa gaaggtaacg atattaatga aaagcaaagg aatgtagctg atcacagaaa
     1981 gcaaaaagcc actgatggca gtaaaaacat aatctgttcc attataagcc actgacatat
     2041 acatttctgc tttagctaga tctttagtag gaatgagttt aggtacaaga gcatcttgaa
     2101 cagtataggt attcaaccca accatagaag ccagaaaaac acaactaaaa ataatggtta
     2161 agctaagact tgcgtgtatc tctcttaagg acattcctaa aataatacct aagacagcca
     2221 ataattgggc ccactccaga atcactagca ggttcttctt agggtacgaa tcaatctttt
     2281 ttccaaagat aaaggagaag gtgtttggaa taaaaatgag aaagttcaat aatccaacat
     2341 accaagtact attagtggtt tctagtacat accaggacag cactagggta taaatcgagt
     2401 caccgcaatt gctaatcagt cgccccagaa ataaccggca aaaatcatta tatttcctta
     2461 atatcatatt gtatcctttg ataaagagtt taaacatctt ttatattata gtatcagatg
     2521 ataaaaaatc actgaatgat agctgtgttt gatgtttgca acattttaaa atatctttgc
     2581 aaaaatcata cctagacaca tacaatccca cataagtttt aaaagcattc aattgccttt
     2641 taagatcttt atgagtcatg tttgtaaaga tatcctcttg caacagatct cttaatctct
     2701 aattgtatcc aataagaagc agctttgtca atacggaagc cgaatagtct ttttgccttt
     2761 ccttgtcagc tgggcaatca tgagggcttt gtgctttgat cttttgcatc tataaaaggg
     2821 tgaatctatt gatgaggtgt tatcggtagt ggggcctact gatgtcaata actgacgtca
     2881 gataattacc tctttaatta gaaaaaaaaa aaaaacgaaa ctacggagag aacctaataa
     2941 ctggctattt cttgatataa gccagcgtgt taaaatcttc tttgggagaa aatttagaaa
     3001 aaaataatat ttctatcact aaggagagaa agatgacaac taaagaaaaa caaacaaaac
     3061 taatgcgcag gtatggcatt ttctcggtag tcgttgccct aacagctcta gcaggtctag
     3121 gagcagctaa tgaagttaag gcaactgcta aaaaatcttt aaatgagtta cctaatccag
     3181 tagaaattat tcaatataat tcaacaagaa ctactgatag agaagctaga aagtatctta
     3241 atcaattata tgagtttttg aaaccttatt taggaagttt agaagaagaa gctcaaaaag
     3301 gagggccaca aggacctgtg ggacctgctg gtcctagagg tgaacgcgga gaaccaggac
     3361 ctaaaggaga ccgaggtcct gagggccaaa gaggtgagca aggcccagcg gggcctattg
     3421 gaccccaagg gcctcgtggt gacaagggtg aaactggaga aattggacct aggggagaac
     3481 aaggtccgac cggtcctact ggtaagccag gagagcgtgg ccctaagggt gacagaggcg
     3541 aacgcggcga aaaaggcgag caaggccagc gtggcgaaaa gggcgagcaa ggccaacgtg
     3601 gcgaaaaagg tgaacaaggc caacgcggtg aaaagggcga gcaaggccaa cgtggcgaaa
     3661 aaggtga
//
LOCUS       DARYMD010000086         3652 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYMD010000086 DARYMD010000000
VERSION     DARYMD010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3652
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..1744
                     /locus_tag="TU818_001873"
     CDS             <1..1744
                     /locus_tag="TU818_001873"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HEL0924641.1"
                     /translation="AIIENNSYLSFNKLKAVGILDPIDYLQRLNGKIGYYTKNYSPLG
                     DCMYLTQENTEKIDNIRQIIEDWNNNQLLTEYEYFYLLNALIEAIPYVSNITGTYGAF
                     LKHWDNRALHSLTLAEETIFDNYRPNKAFNENANELVKKIKADIVYIDTPYNARQYAS
                     NYHLLENIARHQKPILKGITKIFDWKTLKSDYSTKTKALKAMEDLIANINASHIILSY
                     NTEGIISEEDLTLLLQRYSFNNQIDVKRIPYRKYQSKKKSQNKDLYELLFYIQRKPIN
                     NRFKSQTKKKAAIISQKKYIKSPLNYIGGKYRLLNQIIPIFPRHINTFVDMFSGGANV
                     GINVPAKKHIFNDMNYRINDMFRYFQSHDPLEILEQIEHRISEYQLSKTNEQGFLTFR
                     KHYNTHPNPLDLYVLSSYSYNYQFRFNNSMEFNNPFGRNRSHFSENMKSNLLNFVARL
                     HRLDATFSDQFFSDFDISTLSIDDFVYLDPPYLITTGSYNDGNRGFTNWGEKQEIEMY
                     QLIRDLNKKQIKVALSNVLVHKGKHNDLLEQFVQDESLYLTTLNYNYKNASYNTRKED
                     SIEVLITNYKPNPK"
     gene            complement(1765..3378)
                     /locus_tag="TU818_001874"
                     /pseudo
     CDS             complement(1765..3378)
                     /locus_tag="TU818_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677638.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
BASE COUNT         1281 a          702 c          494 g         1175 t
ORIGIN      
        1 ggctattata gaaaataatt cttacctatc ctttaataaa ctaaaagcag taggaatttt
       61 agatccaatt gattatctac aaaggcttaa tggtaaaatt ggatattaca caaaaaatta
      121 ctctcctcta ggagattgta tgtatctaac acaagaaaat actgaaaaaa ttgataatat
      181 cagacagatc atagaagatt ggaacaacaa tcaattactc acagagtacg aatattttta
      241 ccttttaaat gctttgatag aagctattcc ttatgttagt aatattactg gaacctatgg
      301 cgcttttctc aagcattggg acaaccgagc gttgcattcc ttaacattag cagaagaaac
      361 tatttttgat aattatcgtc ctaacaaagc gtttaatgaa aatgctaatg aattagtcaa
      421 aaaaataaaa gcagatattg tttacattga taccccctac aatgctcgac aatacgcatc
      481 aaattatcat ttactcgaaa acatcgcccg acatcaaaag ccaattttaa aagggattac
      541 taaaattttt gattggaaaa ctcttaaaag tgattattca acaaaaacaa aggctttaaa
      601 agcaatggaa gatttaattg ctaatattaa tgctagtcat atcattctaa gttacaatac
      661 cgagggtatt atatccgaag aagatttaac acttttactt caacgatatt cgttcaataa
      721 tcaaattgat gtgaaacgga ttccttaccg aaaatatcaa tctaagaaaa aatctcagaa
      781 caaagactta tacgaacttc ttttttatat tcaaagaaag ccgataaata atcgcttcaa
      841 atcacaaact aaaaaaaagg cagccatcat cagtcaaaaa aagtatataa aaagcccatt
      901 aaattatatc ggtggaaaat atcgactgct aaatcaaatc attccaattt ttccccgaca
      961 tatcaataca tttgttgata tgtttagtgg gggggcaaac gttggtatca atgttcctgc
     1021 taaaaaacac atctttaatg atatgaacta tcgcattaat gacatgtttc gatattttca
     1081 atcacatgac ccacttgaga tacttgaaca aattgagcat cgaatttcag aatatcaact
     1141 cagcaagacc aatgaacaag gctttttaac attccgaaaa cattataata ctcatccaaa
     1201 tccactagac ttatacgtac tatcgtctta tagctataac tatcaatttc gctttaataa
     1261 ctcaatggaa ttcaataacc cattcggcag aaatagaagt cattttagtg aaaatatgaa
     1321 atccaatcta ctcaattttg tagctcgact acaccgttta gatgccactt tctctgatca
     1381 atttttctca gattttgata tttctacatt atcaatagat gattttgttt atcttgatcc
     1441 cccctacctc ataacgactg gcagctataa tgatggaaat cgtggcttca caaactgggg
     1501 cgaaaaacaa gaaattgaaa tgtatcaatt aataagagac cttaacaaga aacaaattaa
     1561 ggttgcactt agtaatgttc ttgttcataa aggaaagcac aatgatttac ttgagcaatt
     1621 tgttcaagat gaaagtctat atctcaccac tttaaattac aattataaaa atgcttcata
     1681 caacacaaga aaagaagata gcattgaagt attgattacc aattataaac caaatccaaa
     1741 ataataaaag catagttgaa ttagctatgc ttttacaaat tcaatttctt tattttgaaa
     1801 ataagatggt aaatcggaaa tatgcagttg tcctttaaga accaaatctg ctcccaaaag
     1861 caattgctct acattgaggg ctgctccctt aatttgtgtt tcattagagg tataatcaag
     1921 ctgctcttga aattttccaa tgaatttact tgacacccac ataaaataaa actcttcttg
     1981 tggaatcgta tctggaaaag cttcccacca ctttatcgga ttacgatttt catctcgtcg
     2041 cttattatcc tcaatatacc gaatcatttc atcagcctga ttgatagatt tagaataacc
     2101 ttttccataa gcctttgtat ctacaatcac accaaaacga tcttgataga gtaaaccatc
     2161 tggctttctg ccaccaccta aaagcttaga atgcaatcta tatacatttc taaataattc
     2221 cattgtaaca atttcaaaat ctcgatttcg cttaccatcg taagcaatat caagcaattc
     2281 aatatatttc attggtaaat tagtctcttt taaaaatttt gccttacgct tttctgcctg
     2341 ctcatccttt aattcttgtg taatttctag ttcaggaata gaaaaatcgt tgatcttatc
     2401 cttcaaagaa actctattgc tagaaatatc tatcctcaaa ccaaaataat tcaatccttg
     2461 aatatctgat aagataatct ccagttcatc gtaaaaaccc ttagccctta gtttatctaa
     2521 tagaatagcc aaagaattag tttcttggag aaacttgacg atataagctc tccgagtacg
     2581 aacatactcg cgattattgc catgagttgc aaaaaattcc cacatcacaa atttttcaag
     2641 cttgctatgc ttagaatccc cctgagcttg tcgtaaagca tgaagaccac gaccattaat
     2701 tttataacct tgaaatccat ctttttcacc attagtaaag gtacgcttaa tcgtttgtga
     2761 atcaaccaaa ccaacatttt ttagccaatt acaaataccg cgtgcatatt tatcacttgt
     2821 tccttctata tcagctttaa taagtttttt ctctgattta gtggcagatc ctaaccaatc
     2881 aaacataata tcttcattat aggaagtaaa gcctttttca ccacgaaaac caagctgctc
     2941 acctaaataa tatttagtac aataagtacc gctatcagcc aataaagata agatttgtgt
     3001 agctggcggg tatgacaaca gtgcctttct taaaatagca gtttcttctt ccgaattaat
     3061 tattgcccta gaaaaatgca accccttcga agtaattgaa aacatatccg tttctctatc
     3121 taccgacaca aaattcaggc taacagccca tcttaaaaaa ccatctgatg tccaattatc
     3181 cgtccaagtt ttacctgtat tttttgcctg ttgaggtacg atgctgattt gaatcaaaga
     3241 atctgccatt gcatctgaac gctttcgggg agatttgtta ttcttatcct ttgatgttcc
     3301 aactaattct aaatatgaaa atgattgaat cccattaatc agtttgtttc tgagtgattc
     3361 tcgtggtact tcaaagaaat ctgtacccaa ccataagttc ttattttcat aagagctcct
     3421 taatcttata cttattatct ttattatagc atataattaa tccttccagt tagcattatc
     3481 acaaagcaac aacatttctt atttaatggg gctactatgt agctatttta atacatgttt
     3541 ttacctcacg aaaacacccc cacttgtcaa gtctgtaact gtactgaccc ccaaaagttg
     3601 gacacgacat attagtgaaa ggatttagtt ctgtattgca cagggctaag tc
//
LOCUS       DARYMD010000087         3386 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYMD010000087 DARYMD010000000
VERSION     DARYMD010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3386
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(360..1334)
                     /locus_tag="TU818_001875"
     CDS             complement(360..1334)
                     /locus_tag="TU818_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL0924642.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTAK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPQTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNFNHP
                     SHRMYDEFIAFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESDS"
     gene            complement(1335..1793)
                     /locus_tag="TU818_001876"
                     /pseudo
     CDS             complement(1335..1793)
                     /locus_tag="TU818_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
     gene            complement(1993..2691)
                     /locus_tag="TU818_001877"
     CDS             complement(1993..2691)
                     /locus_tag="TU818_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL0924643.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            complement(2684..2920)
                     /locus_tag="TU818_001878"
     CDS             complement(2684..2920)
                     /locus_tag="TU818_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL0924644.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGAGEGFSMWAPTPCDVLATDWVEVYD"
BASE COUNT          991 a          847 c          623 g          925 t
ORIGIN      
        1 gcataatgac ttcctccgtt tgtacataga tcatctcatt atagcacaaa tggccttaat
       61 ttgcagaaaa aacaagaatg ctgcaatagt ccttagcttc agacaaactc ccttacctac
      121 cttgactcct tttttaaagc agctagctag agctgcctgt catcgctaag tatcaaagat
      181 gtcgtaaaca aagcaagctg caaattagac ccctcactat gaaaaaagca gttaggctcc
      241 gcgattgaaa gactccgagt catcaggaac aagacctgta tctgatagaa caagaagggt
      301 catcacttct taagacagct agcaaaaaag atgacttagc ttgtagccac tagctactct
      361 tagctatcgc tttctagcga agctgctgcc tgctctaaaa cagccatgac tgccttgctg
      421 tgctccaagg cctgctctgc cctttccatg tccttattag agataatatc tgaaaaggca
      481 ataaattcat cgtacatgcg atgagacggg tggttaaagt tgacggtcct tgcttgctca
      541 cctcgaatgg ctagtaaaag ctctggtaca gcattaggag cacctaaaac agaaagaaag
      601 cctttattcc cctgaatcgt agagacaatc tctgcactgc aatccttagc cccaatacaa
      661 acagccttaa atcgctcata atccatcagc aaaacaccag aggtgtcaac ctgccgctcc
      721 atattagcta ggtactgaac cgtttggggc ttgccaaata agccaacgag cagatggata
      781 ttataaatat tcaaatcacg caaggcccct ccaccctttt taggatcaaa ggctggtgca
      841 atctccccac gcttaaaggc atcataacga gaggaatatt gagaataatt gcactccaca
      901 agcttaatct ctcctaactc agtcaagtga tccttaataa attgggtgtt tggcaaatat
      961 tggttggtaa tagcttctaa taatatcagc tgcttagctc ttgcaatgct gcttaaagca
     1021 tcaagctcct tggctgtcat ggtaaatggc ttttcacaaa tgacatgctt accagcctca
     1081 agggcttgct tagccacttc aaaatgcaaa tgatttgggg tggcaacata aaccgtatcc
     1141 acctcttcat tttttaggac ctcggctagc tgacagctgg cctgttgaat gccaaaggcg
     1201 tcagcaagcg cctctgcggt ttcaagacta cgaggcgttg aaacaatcgc cattaagtct
     1261 atgcttttga tctcctttaa aacaggcaaa acctctttga caatcatgcc tgtaccaaca
     1321 agggctaatt tcatttattt ctccttttta gcagcttcag ggtaaaccct ctgaaactcc
     1381 tctaacacaa taaggctatc ctcggtaaag cgtaagccta cctcttcaaa ataaggtctg
     1441 aaaaaggcct catgaagcag ccgccattct tccaagcttt tatcaccctc tccttcctta
     1501 taggcatgct ctgctggcac gtccttgaag ggaacaagac taaccttagt aatctggata
     1561 atacagatcg cctgatccct actatccaaa atcacgtcat agctgccctc tttggaaagc
     1621 ggctcatgat caggctcata tcagtcatag gcagaggctg tagctgtttt agtgccttct
     1681 agcactaatt gcgctaataa atcaggctca gctccaaagg cccaggcctc agctagatca
     1741 ccaacaccag gattgatttg ctggtattga gaccataatt cttctgcagt catgttatca
     1801 cctctattga tcgaatcctc tagacaggta ggctcctgct gtattaagca aacctactag
     1861 gcactaggct tcatggaaaa aacttcatca gctccctctt agcctgtgac aagattgctt
     1921 gatacagcta tcaactgtca ccctctgtac agacaagcca gatcttgcta ggccttatgt
     1981 cgatgtgctg tttcacttta agctccaacc gccatcaatt ttaacaattt ctccctgcat
     2041 ggcgctagct tttccagatg ccaaaaacat ggtcagctcg gctatttctt cagccctaag
     2101 ccaacgaccg ataggagtct catcagccac ccactgggct aagccacctg gctcaaagtc
     2161 tgtggctgtc attgctgttt gcactgcgcc aggggcaatg ccaaaaacct gaatgcctgc
     2221 cttggcataa tcaagcgcta gctgtctggt aaaaccagcc agagcatgct tgctggaggt
     2281 ataggcagct ccgccgccac ctgccatgaa gctagcaata gagcacatat tgatgataat
     2341 acctgattga gctgtcagca tctgtgccaa atagtgacgc gtgatgcgga cagctgcaaa
     2401 gaaattgacc tgaaagagag cctcaaaatc agcctgtgtg gtatcaagca agggcttata
     2461 ggcatcaaga acgcccgcag tatgacacaa cacatcaacc ctaggcacag cctcaaaaag
     2521 ctcagctaaa tcacctgtaa tatctaactg taaaaactga aaatctcctg ataaatcagg
     2581 cttttttgcc ttgtcaaccc cataaacagt aaagccattt ctcaaaaaca ggcgcgcctg
     2641 tgccagtcct atgcccgatg acacaccagt gatcagcacc cgcttagtca tagacctcta
     2701 cccagtcagt agcaagaacg tcgcagggag tcggtgccca catggaaaag ccctcgccag
     2761 ctcctgacac gttaatcaaa aagtaaggcg tcacctcaag tgccacacca ttttgttcaa
     2821 tgctatcaaa cagctgaaca tagttttcag cgcctcccca gcccttacga acgtattttt
     2881 tcttggcctt caagcctggc aaaatctctt caaatgtcat ggttttctcc ttttataggt
     2941 ctacatcata gcatgagctc ttttaatgat cattatacca atttactcag cttttgtaag
     3001 cttaaagatc acgaaagtcg caaacgtaca agtttgcttt gtttttagat aaggattcat
     3061 catcttaact aattatgaca taatctaagt gatatgaaat cctttgtaac ccacaccagc
     3121 tttttataat acactaacct gagtgtcttt aaaactgcgg ctgtaattct tgattaagct
     3181 aatacagcat gtctagccag tatatgaaaa taattggaat tattttcgtt agaatgttag
     3241 actattttag ataaagcgtg ttcaatgaca ttattttttg tataaatcaa aatatcccca
     3301 aactactatt aggattattt ctttactttt agtcactttt aataaacatc tttaccttac
     3361 acaacatctc atttatacta acccta
//
LOCUS       DARYMD010000088         3367 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYMD010000088 DARYMD010000000
VERSION     DARYMD010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3367
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            127..2313
                     /locus_tag="TU818_001879"
     CDS             127..2313
                     /locus_tag="TU818_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL0924645.1"
                     /translation="MKNFKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGN
                     AYQVFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSD
                     FITVSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKR
                     ASFAVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQ
                     KERNGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIVIHLESFQQFLIDYKLKDD
                     DKDYEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYG
                     GENTQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKN
                     SFQYGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDD
                     ETINGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGK
                     DPETWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQL
                     GQDLLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRA
                     AVAQQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIY
                     SKNGNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
     gene            complement(2425..3144)
                     /locus_tag="TU818_001880"
     CDS             complement(2425..3144)
                     /locus_tag="TU818_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0924646.1"
                     /translation="MPRFSKAFQYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKANAKVLPKT
                     GGAADGLVGLAVGLGLLSVSGYLIYKNRKSGSYVLIALLVAGGATTAVSAVDVVRHLN
                     DIVTKTTVKGVSFTYTPEEKVDDYCYVGYIVTQENSPAPTPEPKPDPVPTPEPKPEPK
                     LDPVPTPEPTPDPEYFEAIPQ"
BASE COUNT         1032 a          720 c          604 g         1011 t
ORIGIN      
        1 tattaaaaaa tcatactaga tttaaactta ttgcaagcat tagctccata tttttggtat
       61 aatttaatct gagattttat ttggagatta tatcttttag gaaaaaatga taaggaagtt
      121 cttactgtga agaattttaa aacatttatc acaagcttta tcaatacaag attaggcttt
      181 gtgctaacgc ttctcttctg cttttggata aaaaccctat gggcttacca tgctgacttt
      241 tcactagatt tgggaaatgc ctatcaggtc tttctaacaa ttattaaccc aatccctcta
      301 gctttgttac tattgggatt taccctttat atcaagaata ctagggcctt ttatatcagc
      361 tcttggatcg tctatattat ccttaacctc ttgttaatat caaattctat ttattaccga
      421 gagttttcag atttcattac ggttagtgct atgctagcca gtagtaaggt ttctgctggt
      481 ttaggagact ctgctttaaa ccttttgcgc atttgggata ttgtttacgt ccttgatttc
      541 atcattctga ttagtttatc agtaactaag accatcaaaa aagacccgcg tccttttaac
      601 aagcgggctt cctttgctgt tacagcactg tcttgcttgc tcttatctgt taatctgttt
      661 cttgcagaga ttgaccgccc ggagcttctg actagaggat tttcaaatac ctatatcgtt
      721 agagcgcttg gattgcctgc ttttaccatt tacagcggaa accagaccta tcaagcacaa
      781 aaagagcgta acggagcaac cgctgaagaa ttagtcgatg ttaagcaata tgtcaagaac
      841 cactacgccg cacctgatcc tcaatatttt ggaatcggta agggaaaaaa tgtcattgtg
      901 atccacttgg aaagcttcca acaatttctt attgattaca agctcaagga tgacgacaag
      961 gactatgagg tcacaccttt tattaattcc ctctaccact ccaatgccac actagccttc
     1021 tctaactttt tccatcaggt caaggctgga aaaacgtctg atgcagagac catgatggaa
     1081 aattcattat ttggcttaaa cagtggttct tttatggtaa attatggcgg cgaaaacaca
     1141 caattcgcca caccatcaat cctagcacaa aatggcggct atactagtgc cgtctttcat
     1201 gggaatgtag gaaccttctg gaatcgcaat aatgcttata agcaatgggg ctatcattac
     1261 ttttttgatt caagctattt ttcaaaacag actgataaaa actctttcca gtatggccta
     1321 aatgacaaat acatgtttag agattctatc aagtaccttg aacagcttca acaacccttc
     1381 tacactaagt ttattaccgt cagcaaccac tacccttaca ccagccttag aggcgaaagc
     1441 agtgaagagg gctttccact agccaaaacc gatgatgaaa ccatcaatgg ttactttgct
     1501 acagctaact atctggattc agccttgaaa tcattttttg attatctcaa ggcgacagga
     1561 ctttatgaca attctatctt tgttctatat ggtgaccact atggtatttc taattccaga
     1621 aatgtcagct tggcagaatt actaggtaaa gaccctgaaa cttggtccga atatgacaat
     1681 gcaatgctcc agcgtgtacc atatatgatc catattccag gctataccaa tggcgggatc
     1741 aaagaaacct ttggcggaga aattgattcc ttaccaacct tactgcatat cttgggcatt
     1801 gataccagca agatggttca actaggacag gatctcttgt cgccacaaaa tagtcaaatg
     1861 gtagcacaaa gaacctctgg aacttatatc acgccagact acactagcta tagcggtcgc
     1921 ctttacaaca ctcaaacagg cttggaaatt acaaaccctg atgagatgac aatggctaag
     1981 gtcaaagaaa tacgagcagc cgttgctcag cagctagcag ctagtgacgc tatccaaaca
     2041 ggagacctac tacgctttga taccgataat ggtctgaaac ctgttgaccc aacaaccttc
     2101 atttatacca agcagctaaa acaactcaaa gagatatcag agaaattagg atcacattca
     2161 accagcattt atagtaaaaa tggcaacaaa tcaactcaaa agctctttaa agcaccttct
     2221 tatctggagt taaatcctaa agaagccgaa aaacctgaat ctacttcgtc ttctgaccct
     2281 aaagaagaat ccgttaagga acaaagtcag tagtggatgt ctaaagcaag cctcactagg
     2341 atcgctctcg tagaagacta aaagcaagct aaaagccttc attgagcgtt acaacttaat
     2401 gagggctttt tagttctgac acttttattg aggaatggcc tcaaagtatt ctggatctgg
     2461 tgtcggttca ggtgttggca caggatctag cttaggctca ggcttcggtt ctggtgttgg
     2521 cacaggatct ggcttaggtt cgggtgtcgg tgctgggcta ttttcttgcg tcacaatata
     2581 acccacataa cagtaatcat caaccttttc ttctggagtg taagtaaagc ttaccccctt
     2641 aaccgtagtc ttagtgacga tatcattgag atgacgtacc acatcaactg cactaacagc
     2701 tgttgtcgca ccaccagcta ccaacaaggc aatcaacaca tagctaccgc ttttcctatt
     2761 tttgtaaata agatagcctg aaacacttag taagcctagc cctactgcca aaccaaccag
     2821 accatctgct gcaccacccg ttttaggcaa gaccttagcg ttagccttag gggtagacat
     2881 cattcctttt ggagatgctg tcactccaca gcttttgtcg taaacaagaa cgtaatgcaa
     2941 tttatcttgg ataggtactt catttggagt gcctttttga atgcctgctt tttgttcatt
     3001 tgtcagatta gaataggctg tataggtcaa atctaccgtt accgtatcag cattagtgtt
     3061 ggcattgaca ttagctgcta gcaaagatag acctaacatc gttgtagctc ccatgtattg
     3121 aaacgcttta gaaaaacgtg gcattataac tattctcctt aatgttttgt agaataaaac
     3181 caataactaa aaaggcatct cctatcatat caatcttatg attattatag gtaaatgtga
     3241 tttttgtaag cactatctaa aaatttcaaa tacactcata tcaatagata ttgaccaaat
     3301 ctcagcagct ttaagcatat cataacaata aatcacctta ttgacacaaa tagaaaggac
     3361 acattta
//
LOCUS       DARYMD010000089         3350 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYMD010000089 DARYMD010000000
VERSION     DARYMD010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3350
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..396
                     /locus_tag="TU818_001881"
     CDS             <1..396
                     /locus_tag="TU818_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0924647.1"
                     /translation="YVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNIL
                     QEVGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLFLFGVLDTNLIYLV
                     SALTIAVIIVIYFTIYRITSKTYYNIIER"
     gene            440..1105
                     /locus_tag="TU818_001882"
     CDS             440..1105
                     /locus_tag="TU818_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0924648.1"
                     /translation="MIKAGKIYIVEDDAAILTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDIILMDITLPFFNGFYWTTEIRKTSTVPIVFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILT
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDRIHTVRGVGY
                     IIK"
     gene            1102..2079
                     /locus_tag="TU818_001883"
     CDS             1102..2079
                     /locus_tag="TU818_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0924649.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLGYFKVTSLTI
                     LTLLILQGFGNYIRFKKKMKILQEFIYVKELDQLHSPSEQAYRSLIIKLKEAEAEVAL
                     YQLNNQKNTEALIKMWSHQMKLPLAAMSLMLQTNHIDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVCSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLNITISSQVDQGTLVVIQKKHSKQTKFSTSLL"
     gene            complement(2179..3249)
                     /gene="xerS"
                     /locus_tag="TU818_001884"
     CDS             complement(2179..3249)
                     /gene="xerS"
                     /locus_tag="TU818_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL0924650.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNIYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEYKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDKL"
BASE COUNT         1052 a          622 c          620 g         1056 t
ORIGIN      
        1 tatgtcctaa ccggtggctt cctttttaca ggctttcttt taggcttgag ctttgtactt
       61 ggggctgcac tgatcattta ttacaagcaa tactctgaag gctatgagga taaaaaatct
      121 tacaatattc ttcaagaggt cggcatgagc aaacaacaag tcaaaaaaac catcaattcc
      181 caaattgtat tagtgttctt tatgcccata gctatggcag tcctacattt ttgtgtcgct
      241 ctggttatgc ttaagcaaat gctctttctc tttggcgttt tagacactaa tcttatttac
      301 ctagttagtg cgctgaccat tgctgttatt atcgttattt actttactat ttacaggata
      361 acaagcaaaa cctattacaa tattattgaa agataagacg agtggcgatt tttcgccact
      421 tttttgataa aataatatta tgattaaagc tggaaaaatt tatattgtcg aagatgacgc
      481 tgctatctta acacccttaa aagagcatct gagtcagaac taccaggttc ttaccgtctc
      541 taactttaga gacattaagc aagaggtgat tgattataaa ccggatatca tccttatgga
      601 catcacctta ccgtttttta acggctttta ctggacaaca gaaattcgta aaacgtcaac
      661 agtgccaatt gtttttatct caagcagtaa tgatgagatg gatacggtca tggcacttaa
      721 tatgggggga gatgatttca tctctaaacc cttttctcta accattttag acgcaaaaat
      781 cgcagccttt ttaagacgct cacagcaatt tagcagtgat gatgtgacca tagatcaatt
      841 taagctacat tttgatggca ccttatctaa tggcacagat agcattcatt tatcgccaac
      901 agagcacaaa atcttaacga ttttatttac tcacccgcag caaattgttt caaaggagga
      961 tattctagca aggctttggg aaaacgagag ctttattgat caaaacacgc ttaatgttaa
     1021 catgacgcgt ctacgcaaaa aaatatcagc tattggtttt gaccgtattc acacagtgag
     1081 aggagtaggc tatattatca aatgataaga gcatttttta aggaatatta ttcctggtat
     1141 atccagtatg gggttgttat ggctggttat ctgctgatct tttggcttta taggcttcct
     1201 ttaggctatt ttaaagtgac tagcctaacc atactaacct tgctaatatt gcaaggtttt
     1261 ggaaactata ttaggttcaa aaagaagatg aagattttac aagaatttat ttatgtaaaa
     1321 gaactagatc agctgcactc ccctagcgaa caagcctata ggtctttgat tattaagctt
     1381 aaggaagcag aagcagaggt agcactgtac caacttaaca accaaaagaa tacagaagca
     1441 ctgattaaaa tgtggtctca ccaaatgaag cttcccctag cggctatgtc cttaatgctt
     1501 caaaccaatc atattgatat taaggattat cagattcagg ttctacgctt ggagcattac
     1561 ctcaacaatc tattaagcta tttgaagttt aaccagcata gtgatgattt tcggtttcag
     1621 gtttgctctg taaagcagct tgtgacctca gttatcaaaa agtccagcca gacttgtatc
     1681 gctaagggga ttagcattgc agttgatggc gattggcaat tgagcactga caacaaatgg
     1741 ctgtcatttg ctctgacaca aatcattgac aatgcaatca aatattctaa gccacaaggc
     1801 cacatcaaag tcagcattaa ggaaggcagt atttttatat cagataatgg tattggaata
     1861 ctagaggaag atttgccacg tctgtttgaa gaaggcttta ctggctacaa tggccatgag
     1921 catcaaaagg caactggttt aggcctcttt atgacaaagc aaatccttga taaattaaat
     1981 ttaaacataa ctatttccag tcaagttgac caaggaactt tagttgtaat tcaaaaaaag
     2041 cattctaaac agaccaaatt ctcgacttct ttgctgtaaa aaataacagc tataaatccc
     2101 tataatagtg acaaagagga ttaaaacatt gcaaaaaaag actgaaagta cagattacat
     2161 aattttagtt atgtaaattt ataatttatc tagggcattt ttttgctcat cgttaacaat
     2221 atgagtatag aggtctgtaa cttgggtcga ggcatgacca agctgatgac ttactaggac
     2281 ctgtgacttt gtagtatcat aaagtctcgt tgcaagcgta tggcgtagct tatgaggagt
     2341 tacacgaatt ttaaagcctt cagaatattt acctaccatt ttttcaatgc ttgaggcatc
     2401 tatccgattg gggagcccac gataggctgt taaaaagaag gctacatcct gtttttctgc
     2461 ttgatagcgg tcttttcgaa ctgataaata ggcttctaaa tgaggcttgg caaaagcagc
     2521 aacattgacc gaatctctct tacctccctt acgggtaacc tcaaccagca tcatgttgag
     2581 gttgacatcc ttaaggtcta ggttaactgc ctcggataac cgaataccag atgccagcag
     2641 tagggcgata atggctaggt cgcgttcttt attttttcgg aaagaagcct ttgcccgatt
     2701 tgacagctta tattcatatt ctttatccac atagtctaaa aatgccatcg tctcatcgcc
     2761 taaaaaaagc ttttgtttaa tattttcagc cctggctgct aaggtttctc ttttcttttt
     2821 ggttgccacc tttttcatga catttcgata aaaataaggc tctccatgct cattttcaac
     2881 ctcctcagta aggtatttat acaagctgga tagtgcagaa agggtacgat taatggtggt
     2941 ttgcgatacc ccctttttag ttgaatagat gttcaaggaa ggacgctcac gaagatagag
     3001 aataaaggct tccatatcct ttttactcaa atgctccaga gtagtcaagt ccacatcagc
     3061 aatcctagca gcttttgata gatcagaatc aattaaccac tcaaaaaagc gtttgtattc
     3121 tttcaggtat tcgtacaagg tcgtaaagct ataaggaaca gatagcttag attgataata
     3181 atcaaggaca taccaaggca tgatgttttt gtattcttca attttagtaa gtagtaaatc
     3241 acgtttcata ataaattctc acaatgtttc gtcaacaaat gaattatcca ttggatatca
     3301 gactgatagt agtatatcac atcttggggt atttttcaag aaaattatag
//
LOCUS       DARYMD010000090         3255 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYMD010000090 DARYMD010000000
VERSION     DARYMD010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3255
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..1555)
                     /locus_tag="TU818_001885"
     CDS             complement(<1..1555)
                     /locus_tag="TU818_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0924651.1"
                     /translation="MFYLKLAWNNLRKSLSVTAPFLLASTVLYMLNCIVLIIMMSPVS
                     ESMRHGFMLLGLAIFVLIIFATIMEIYSYNFLLKQRSREFGLYNILGMNKKQVGLVST
                     IELVFMYLGTVVVGSILSAIFSHVFYLIFANLVGAVHLELQINPVAFIYTTLIFAAIF
                     GLLEVVGLIKIRKTSPLMLFRHKEQGEKEPKGNLLLAALSIILLSIGYYISLSSTKLT
                     ALDTLYRFFIAVIIVIIGTYLFYISFMTWHLKRRRQNKAYFYQPEHFVSTSQMIFRMK
                     QNAVGLANITLLAVMAFVAIATTTALYANSEAMSNQLFPKNTHINFDNSEIDNQKEVF
                     NRLIVEKTNKPASDFLVYYSSMVSFEVSQKETIVVTKESLLNPSPVTTGYVYLVTQDD
                     FRALGNQLPELKDNQTAFFKQRGDSQLRQLDILGKSYTNVKNLTSVTFPEAANTYNGA
                     VLVVKDMETLKDIQDSIQSINHTGGRASISAYADLTKADLRSISDDKGIISDGDTVIG
                     HIETKKEYLR"
     gene            complement(1558..2310)
                     /locus_tag="TU818_001886"
     CDS             complement(1558..2310)
                     /locus_tag="TU818_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924652.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            2641..3120
                     /locus_tag="TU818_001887"
     CDS             2641..3120
                     /locus_tag="TU818_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL0924653.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQKIADTIEAVKQIKLPFKKR"
BASE COUNT         1036 a          605 c          609 g         1005 t
ORIGIN      
        1 atcggaggta ttccttttta gtttcgatat gacctataac agtatcacca tcactaatga
       61 ttcccttatc atcactaata ctcctaagat cagccttagt taaatcagca taggccgaaa
      121 tgctggccct tccgccagta tgattaatgc tttgaatgct atcttgaatg tcctttagtg
      181 tttccatatc tttgaccaca agaactgcac cattataagt gttagctgcc tctgggaagg
      241 ttactgatgt taaatttttg acattggtat atgatttgcc caaaatatcc agctgtcgta
      301 attgactatc ccctctttgc ttaaagaagg cagtctgatt gtcctttaat tcaggcaatt
      361 gattgcccaa ggcgcggaaa tcatcttgag tgactaagta gacatagcct gtagtgactg
      421 gactaggatt tagcaaggat tctttggtta ctacaatggt ttctttttgg gatacttcaa
      481 aagaaaccat gctactataa tagactagaa aatccgaggc aggcttattg gtcttttcaa
      541 caataagtct gttaaaaacc tctttttgat tgtcaatctc tgaattatca aaattaatat
      601 gagtattttt aggaaaaagc tggttagaca ttgcctcgct attagcataa agcgcagttg
      661 ttgttgctat tgcaacaaag gccataacag ctaagagggt aatatttgcc aagcctacag
      721 cattttgctt cattctaaaa atcatctgag aggtgctgac aaaatgctct ggctggtaaa
      781 aataagcctt gttttgacga cgacgcttta agtgccaagt cataaaggaa atgtaaaaga
      841 gataggtccc gataataacg ataataactg ctataaaaaa ccgatataaa gtgtctaatg
      901 ctgtcagctt tgtcgatgat aaggagatgt aatagccaat actaagcaat atgatggata
      961 aggctgctag taataaatta ccctttggct ctttttcacc ctgttcttta tgacgaaaga
     1021 gcattaaggg agaggtcttt ctgattttaa tcaagccaac aacctctaat aaaccaaaga
     1081 tagcagcaaa gattaaagtg gtgtaaataa aagcaacggg attgatttgt aattctaaat
     1141 ggactgctcc gaccagatta gcgaaaatca aataaaagac gtgtgaaaaa atagctgata
     1201 ggatacttcc tacgactact gtccctaagt acataaaaac aagctcgatc gttgagacta
     1261 aaccaacctg ctttttattc attcccaaaa tattgtacag accaaattct cgacttcttt
     1321 gctttagtaa aaaattatag ctataaatct ccataatagt ggcaaagatg attaaaacaa
     1381 agattgctag tcctaatagc ataaacccat gtctcatcga ttctgatacg gggctcatca
     1441 tgataatcaa gacaatacaa ttgagcatat ataaaacagt gcttgccagt aaaaaaggag
     1501 ctgtgacgga taaggacttt cgtagattat tccaagctag tttgagataa aacatcttta
     1561 ttcacctcct aaaagaccgg ccatggcaat cgagatgtct ttgctaaatt ctaaattcgt
     1621 tttatttcca cgatagattt ggtggaaaat acggccgtcc ttgataaaca gtactcgctt
     1681 agcatggcta gcagcattgg cagagtgtgt taccatcaag agtgtctgac cgtctaggtt
     1741 aatggcctca aaaagattga gaatatcctc tgaattgcgg taatcaagtg ctgctgttgg
     1801 ttcgtcagct aataataatt gcggattggt gattaagctt cttgcaatag caaccctttg
     1861 cttttgacca ccagaaattt caaatggacg tttatctaaa agcgtttcaa tgcgcagctt
     1921 aggggcaatg atgttgagcc gtctttccat ttctttaaat ggcttacggt ttaaaacaag
     1981 gggtaaaaag atattatctc tgatcgatag ggtgtctagg aggttaaaat cctgaaaaac
     2041 aaagcctagg ttttgaagtc ggaaattagc taggtcaccc tccttaattt ttgtaatgtc
     2101 agtgccattc aataaaacag atcccttggt tggtttttcc agagttgcca gaatatttaa
     2161 tagggttgtt ttccctgagc ctgactctcc catgatggca ataaactcac ccttgtcaac
     2221 cttaaaatca acatcttgta aggctctagt ttcttccttt gaaaagcgtg tccgaaaaac
     2281 cttctctaaa tgattaattt ctaataacat atgaaactcc tttgtgtcta ttatactctt
     2341 ttagctttaa atatagccac tatcgtgacg tatttagcta gtgatgcatt tagtgccttt
     2401 tgtcagcctt aaccactcct tctttcatga agcagcccag ctctcaacaa gaatcgtctt
     2461 agctgactga acctattgct ctaaactctt ttttctttac agcttatagt ttaccctaat
     2521 taatagtctg gttagcttac aagatttgat gggtgactta cagatttgta agttttataa
     2581 catcattttt cttatcattt tgatataatg aaaggagaat tctatttagg agaagcgtca
     2641 atggctaaga aaatcaaaaa aacgctaggg actgtcggaa agctgttttc cattatccct
     2701 gataccactg aaattatagg aaaaacgata gataacaccc gtcccattat cgaaaagcat
     2761 atggaacaaa agcatgaaaa ggaaatgcag ctaacgcttt tagatgatgt gattaattta
     2821 cctgttgata aagcgcaaaa gcatctggaa cagctaggtt ttgttgtcgc actattgccg
     2881 gtcaagccta gtaaaaaatg gatacatgct agcttaaatg aggttgtttc catgtcacct
     2941 aagcctggaa agcataagct gggaagctta gtaaagcttt attatgttac tgtagatgtc
     3001 cttgagaaaa gtcaggctat tttagatcaa gagaccctaa aggctgtcga acgaaatcaa
     3061 aaaatcgctg ataccatcga agctgttaag caaatcaagc ttccttttaa aaagagataa
     3121 ggctatactg taaaaaataa gctgataccg ttaggatcag tttatttttt atgttgtgac
     3181 tttaagtcta tctcgcttag caggtgccaa acaaataaac cacccgttat gtaccgacct
     3241 tcaatggtta aagtt
//
LOCUS       DARYMD010000091         3082 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.092, whole genome shotgun sequence.
ACCESSION   DARYMD010000091 DARYMD010000000
VERSION     DARYMD010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3082
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            309..659
                     /locus_tag="TU818_001888"
     CDS             309..659
                     /locus_tag="TU818_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0924654.1"
                     /translation="MFSTFEKIKELCKSRGISIAKLEENLGLSKNAIYAIKRNQPSAE
                     RLQEIADYFHVSTDYLLGRTDNPKIAQSDHTPSAIDLKKDAEETFFFDGHELNDEDID
                     LITSILETRIKNRK"
     gene            673..1077
                     /locus_tag="TU818_001889"
     CDS             673..1077
                     /locus_tag="TU818_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL0924655.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     TYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLREELSYWDNVEEFNYVR
                     FMQQYDLTSFVDEVMVKEEYYNLTGYYDKKSF"
     gene            1105..1659
                     /locus_tag="TU818_001890"
     CDS             1105..1659
                     /locus_tag="TU818_001890"
                     /inference="COORDINATES: protein motif:HMM:NF020376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HEL0924656.1"
                     /translation="MSSNTYYKNLTNKKIINYLQSSHTGRIYKYNYLKSNEVKLVREP
                     NNKHDQNAVKILVKNIFIGYIPHEIAKEINRYLKNKKYNYDASISIYGGPYKTIDMDL
                     DIIEHQLNINCDIALCILSNTSKSKSKNITFTDAIAAIMFLIGILFCLVAISFLLKGK
                     FLEFLVGLFFTLVLSIPAYLKFSK"
     gene            1837..3003
                     /locus_tag="TU818_001891"
     CDS             1837..3003
                     /locus_tag="TU818_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL0924657.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWNMYVDNRLKTGSWKPDTEANKEAIYK
                     THFKKYLGKTKMKDISRIEYENHINGMRKNYSKNTLRLIHSVLNAMLNHAVTNKMLDD
                     NPIDGITIGDSEIIPVNKRISLEEFKEWDSWAKKSLIQYDYTIVRMTYFGARSSEVVA
                     IKIGNLTKLENGRYRILLDESRTYHRPNGGGMKTPGSERFMEVDLETSHYIDDVVVES
                     KRIAKKYNRILSKEDYLFLTNFKNAKKELLGMPISIRRVYKLFNTVNEKSGMHVTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSTSYMTSKYTHIKEEVAGSVTDRFMSALN"
BASE COUNT         1165 a          500 c          521 g          896 t
ORIGIN      
        1 cgatcgggag ttttttattt aaatgaaaag cgaatttttt tgcgaaaaat tttttatagt
       61 ttactcttga caatgattag agaataaact acaatcaaca tatagaaaaa aacactaaca
      121 aatagcttaa taacactaac tatcttaagt cgccaaactt tattttttta gttttatttt
      181 cgctttttgt ttcgcttatt tattcgcttt acaaattata ttttagagta ttctcttgtt
      241 tttgtcaaca ataaaataga tatttctcta aaatattttt cgtgatgctt agaaaggttg
      301 atatatcaat gttttcaaca ttcgaaaaaa tcaaagagct ttgcaaaagt agaggaatct
      361 ctattgcaaa gctagaagaa aatcttggat taagtaaaaa cgctatttac gcaatcaaga
      421 gaaaccagcc gtccgctgaa cgtcttcaag aaatcgctga ctacttccac gtctctacag
      481 attacctttt aggtcgcaca gataatccta aaattgcaca aagtgaccat accccgtctg
      541 caatcgatct aaaaaaagat gcagaagaaa ctttcttctt cgatgggcat gaactcaacg
      601 acgaggatat agaccttatc acatctatat tggaaacgcg catcaaaaat agaaaataga
      661 gaggacagct ctatgatgac accagaaaca gtctgtcagg aaaagggaat cgatttagtg
      721 tacttcgacg gtagggggac aaacacccct ggaatgttta acaaaaaaca caacgtcatt
      781 gcgattgaca cttatcttga cggcacatac aagcacaaag tcatctatca tgaactagga
      841 catagagaac atactgcgag ttattacaag ctaaacaaag aaaaagcaga gctacaagct
      901 gatagatgta tgatacatca cttgctgagg gaagaattgt cttattggga taatgtagag
      961 gaatttaact acgtccgatt tatgcaacaa tacgatctaa cttcatttgt cgatgaagtc
     1021 atggtcaagg aagagtatta taatttaaca ggttattatg acaaaaagag tttttaattc
     1081 tagctttcaa gtagctggaa cagtatatca tcaaacactt attataaaaa tttaacaaat
     1141 aaaaaaatca ttaactatct acagagtagc catacaggca gaatttataa atacaattat
     1201 ctaaaatcaa atgaagttaa attagtacga gagcctaata ataaacatga tcagaatgct
     1261 gttaaaatat tagttaaaaa catttttata ggctacattc cgcatgaaat agctaaagaa
     1321 ataaatcgtt atttaaaaaa caaaaagtat aattacgatg catctattag catttatggt
     1381 ggaccatata aaacgattga tatggattta gatatcatcg aacatcaatt aaatattaac
     1441 tgtgatattg cactctgtat tttgtcgaat acatcaaaaa gcaaatctaa aaatattaca
     1501 tttacagatg caattgcagc aataatgttt ttaattggta tcttattctg cttagtagct
     1561 ataagttttt tgcttaaggg taaattctta gagttcttag ttgggttgtt ttttacatta
     1621 gttttatcaa taccagcata tttaaaattt agtaaataaa acaaaaaagc cccacgttac
     1681 aaccgaccaa agcgcaacgt ggagactaca caaaatataa aacaaccatt aaaaagggcg
     1741 ttttattata cctaattata tcacacaaag gaggtgatgc caatatcctt tcaaacgacc
     1801 tcgtccaaaa gtcaaaatac atgaaaggat tttaaaatga aatacaacaa aacaaaatac
     1861 ccaaatatct ttacctacga tacaaagaaa ggtaaacgct actacgtccg taggggttat
     1921 tacttaaaag gtaaaaagaa agaggctaca aaaagcaact taaaaacgct acaggaagcc
     1981 agagctgcac ttactgaaat tgagcaaaaa atagaaaaca atgattttgc ttataacaaa
     2041 aatttgacag ttgatcagta ctggaatatg tatgtagata atcgcctaaa gaccggatca
     2101 tggaaacctg ataccgaagc aaataaagaa gctatataca aaactcactt caaaaaatat
     2161 ttaggcaaga ctaaaatgaa agatatttct agaattgagt atgaaaatca tattaatggt
     2221 atgcgtaaga attattcaaa gaacacttta cgcttgatcc attcagtact caacgcaatg
     2281 cttaatcatg cagtcaccaa taaaatgcta gatgacaatc caattgatgg gataactatt
     2341 ggcgatagtg agattatacc cgttaacaaa agaatatcgc ttgaagaatt caaagagtgg
     2401 gattcatggg ccaagaagtc attgattcaa tacgattata ctattgtccg tatgacttac
     2461 ttcggagctc gtagtagcga agttgttgcc ataaaaattg gcaatttaac aaagcttgaa
     2521 aatggtagat atcgaatatt gctagatgag tctaggacgt accatcgtcc aaacggtgga
     2581 ggaatgaaaa cgccaggatc agagcggttt atggaagttg atcttgaaac atcgcattat
     2641 attgatgatg ttgttgttga gtctaaaagg attgcaaaga agtataatcg tatattatca
     2701 aaagaggatt acctattttt gactaacttt aagaatgcga aaaaagaact tttaggaatg
     2761 ccgatctcta ttaggcgagt ctataaactt tttaatactg tcaatgaaaa atctggtatg
     2821 catgttaccc cacacatgat gcgccacttt ttcgccaccc aagggcagat agcaggtgtc
     2881 ccaattgaac atatggccgc agcactaggt cattctacaa gttacatgac tagcaaatat
     2941 actcacataa aggaggaggt tgctggtagt gttactgata gatttatgag cgctttaaac
     3001 tagttagtcg gggaaattta tacaaatgct taaattaaca aatcccccga tatattcccc
     3061 gacaatttat agatttttat ta
//
LOCUS       DARYMD010000092         3059 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYMD010000092 DARYMD010000000
VERSION     DARYMD010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3059
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            121..594
                     /gene="tnpA"
                     /locus_tag="TU818_001892"
     CDS             121..594
                     /gene="tnpA"
                     /locus_tag="TU818_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL0924658.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTVGLNKRTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            881..1346
                     /gene="tnpA"
                     /locus_tag="TU818_001893"
                     /pseudo
     CDS             881..1346
                     /gene="tnpA"
                     /locus_tag="TU818_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(1528..1683)
                     /locus_tag="TU818_001894"
     CDS             complement(1528..1683)
                     /locus_tag="TU818_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL0924659.1"
                     /translation="MEKQNSLTQFQELNSSELNQITGGDWWSEILNFNRSQKYKHTSV
                     GSNNIIV"
     gene            complement(1777..2976)
                     /locus_tag="TU818_001895"
                     /pseudo
     CDS             complement(1777..2976)
                     /locus_tag="TU818_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
BASE COUNT          970 a          479 c          602 g         1008 t
ORIGIN      
        1 ttctcgtaga gaaaaacaag aaaaccacca gctatgctgg tggctgacaa ggctttgagc
       61 ttccatttct ttttcctgtt ataatctaat tgttcaggtt agatcaagga ggaaaaagag
      121 atggctaaaa ccagttacag tttatcacat accaaatgga tgtgcaaata tcacatagtt
      181 ttcacaccaa agtaccgcag aaaatccatt tactacaaaa ttagacagga cttaattgat
      241 attttccgtc acctatgtca atacaagggc gtggaaatca ttgagggaca tatgatgcca
      301 gatcatgttc atatgctcgt cttgctacct ccaaaacttt cgatttccga tttcatgggg
      361 tatttgaaaa gtaaaagtgc tctcatgata tttgataaac acgctaattt aaaatataag
      421 tatggaaatc gaaagttttg ggctagaggc tactatgtta gtaccgttgg actgaacaaa
      481 aggacggtag cgaaatatat tcgcgagcag gagaaaaatg acattgcact tgataagttg
      541 agtgttaaag aatatgaaga tccattttca gatggcagtt ttaaaacaag ataaaagccc
      601 gtttttacgg gcattagtca agtaatcata gcactaacct gaacgaagtt cagcgaacgt
      661 ctttagacgt cgctggagag aaacggctta tagccggtgt acaagccacc cgtttttacg
      721 cgtggttatg acttagtgac tttagtccgt ttcgctccgt aggtgcgaaa caaaaatccc
      781 ccgctatgcg ggtacgcatc gaacgttata ctacaaaaaa actccaaacg cgctacaata
      841 taggtgttca agccaattgt aaagcgaaag gagtaaaaat atggcacaaa agccccacag
      901 tttatcgcac acaaagtagc attgtaaata tcacattgtg ttcaccccta agtatagacg
      961 aaaagtaatc tataatcaat atcgaggcag tttgggagaa atttttcaaa gattatgtag
     1021 ctataaaggt gtagaaatat atagaaggac atctgatgcc agatcacgta cacgtgttag
     1081 taagcattcc acccagaata agtgtttcaa gttttatagg atatttaaaa ggtaagagta
     1141 cgcttatgat gttcgacaag cacgccaatc tgaaatacaa atttggtaat cgacactttt
     1201 gggcagaagg ctattatatt agtacggttg gattaaatga agctacaata aaaaaatata
     1261 ttcaagaaca agaaaaacat gacatagcac tagataaact gagtgtaaaa gaatatgagg
     1321 atccctttag agataagggt aagtgataca aatacttctt tgagaggcaa gtgacgagtc
     1381 aatagcaatg tggtttgaac aaagtgaaag ccagcgtctt taggcgctgg ctagttatat
     1441 gggtttatag tccctattca aaccacctgt tggacgggtg gttatgattt ctactaaaaa
     1501 aactattatt acaatactaa gtatatgtta gacaataata ttattagaac ccacggaggt
     1561 atgtttatat ttttgagagc gattaaaatt taatatctct gaccaccaat ctccacctgt
     1621 tatttgattg agttcggatg aatttagttc ttgaaattga gtgagtgaat tttgtttttc
     1681 catttgtgga cctccttctt ttttctaata ttataattta agatcaatat attatttctc
     1741 taaatcctaa atggtcatcg aaacgtccgg aatggtttaa tcatgatttg acaacagttt
     1801 attcttataa aagtcgaagt aggatttttt agcgataaca cttgtaacac gaccctgtgc
     1861 accatatttt atcaagtagc tatccttgga agggagtttg gcaagagttg taatcttgaa
     1921 aagattacct tgttctgttt ttgttgctgt tttatcaata gtagaaattt ttccattaac
     1981 agtgatggac tgttttctca ctttttgaag atttagacga acagtttgac cttttttaag
     2041 gagagaaaca taatcagaag ttacaaagta tgtaatcaga gcttttctag tttgagtaat
     2101 attaggatag attttggcaa tatcactacc atttgggata agacttttcc cctcgtattc
     2161 attatttaga tgaataatcc tggtttctgg tgctaaaaca acattagtgt ctaactatac
     2221 acttgcttgt tctagctgag ctttaagttc agtgatttga ctgtcgatgg ttgacagctg
     2281 ttgtgaagca ttctgtagaa attgagtcct caagacttca actttggttt ctgaactgtt
     2341 atcgtatgtt gcactactac cagtacctgc tctttgaatg ctaagcccag agagggatga
     2401 ttctaaacct gaaatagtct ggttaatctg agagataaac tggttagacg tggaagttta
     2461 ttcttcttgt gattgagaca gataattatt gagaatatct tgatgaggat taccagttgg
     2521 taagattgtg ttatgatttg agatagcttg acgaagatct tcatattctg aaatctgctg
     2581 gtttatagta ttgatttgag tatcaattgc agcaagggtg ttatttgcaa gtgtggattg
     2641 attggatact tctgtattta ttttagcgat accaagttta atctcttgag actgatttat
     2701 aaagttgttg aaggtgtcag caagaccaaa ttcatcattt tgtggtaaga ggttcgttcc
     2761 ttgtttgaga ctttctttca atgtctctaa accaactttt tgtttattca acgtatttaa
     2821 ttgtgattct agagaattct tttgagaact ctcaatggtt tctttatatt tgattaaacg
     2881 ttttcctttt ttaacgagtt ggttttcttt aagattattt ttaacgatag cattgttgct
     2941 agttgactgt attgatgcaa tgacttttgt aggcataatt tcacctcgtg acgataccgt
     3001 tacttctttt tgaccaagaa aagaaaatga aagtaaaaat atgacgaata atgttaatg
//
LOCUS       DARYMD010000093         2495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYMD010000093 DARYMD010000000
VERSION     DARYMD010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..1244
                     /locus_tag="TU818_001896"
     CDS             <1..1244
                     /locus_tag="TU818_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924660.1"
                     /translation="RRSYHRSSFFIKTGSIVMVLYLAIVSILGLTDYLSMRQYIPTWE
                     SSKYYANMACAWSWSYEKDDDKFHEIVIPKLNNLWNSLDDSGAILFNAPNVRKEGMND
                     DEEYLNQQPFQGNYAYVNKNYLHIANLLDKDTNKIEQYKIHENEWIVFVPEDVKITEL
                     DKEKIHEDHIFQNIKKQGTIIETYVRLKDNQSVFSFDSGKRIDEANLKNYVLVAVNGK
                     ELLPDHGIKLSSLVNGQLHPYVKEPSRAYESLKDIIEETESEPFILYISSVYDDIVSR
                     IDEYKMEASIYVIGLVLSIVILATLLKIDKETYFYNHGQRIDVSRLLGYGFFDIHHKK
                     IIGNIVGYIISIIILFMVIMVTGVISDVGLFIPRDGWSMSKLLISLIIGICGSFICFG
                     IEILQLKKSERSIVLRLKEGC"
     gene            1245..1919
                     /locus_tag="TU818_001897"
     CDS             1245..1919
                     /locus_tag="TU818_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0924661.1"
                     /translation="MQNEKELQITLRNVSKKYGEHSILENISLDIYKGDFVCIFGKSG
                     GGKTTLLNIIGTLENYDSGSVTCFSNRDPIKAPKVGELLRREKIAYLFQNFALVEKMT
                     VEENMMLAAKYNQEKNKKNLIEAALNKMGISDKLKSKVYELSGGEQQRVALARNMIKP
                     FEIMLADEPTGSLDYENKKIVIDTLIRLNDEGKTIVVVSHDKDFEKVAHKNYIIEKSA
                     IREVLR"
     gene            1916..>2495
                     /locus_tag="TU818_001898"
     CDS             1916..>2495
                     /locus_tag="TU818_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0924662.1"
                     /translation="MKRKIALLVPVIVLCICGLFFYMNRNSDDIDVAFTVKNETKEKI
                     DTVGIAMGNKCILNRTNGEKFYFPKDLIKEKQGKAIVFVVSKDGIIAKSGEIDLKENK
                     EVSIREIKEGEISLDIAAQKTDIKISIPRLDDWKVSTDEKFIKGSYEANTDSQYTLYL
                     LGKGGNLGISGTEMKGVRVIVSWEKPKDKIDSW"
BASE COUNT          975 a          248 c          503 g          769 t
ORIGIN      
        1 atagaagaag ttatcataga agttcttttt ttataaaaac agggtcgatt gttatggttc
       61 tttatctagc aattgtaagt attttaggac tcactgatta cttgagtatg agacaataca
      121 ttccaacttg ggaaagctca aagtattatg caaatatggc ttgtgcatgg tcttggagtt
      181 atgaaaaaga tgatgataag ttccatgaaa ttgttattcc aaagctgaat aacttatgga
      241 atagtttgga cgatagtgga gcaatattat ttaatgcccc aaacgttaga aaagagggaa
      301 tgaatgatga tgaggagtat ctaaatcaac aaccttttca aggtaattat gcctatgtaa
      361 ataaaaatta tttacatatt gctaatctct tagataaaga tacgaataaa atagaacaat
      421 ataaaataca tgaaaatgag tggattgttt ttgttccaga agatgttaaa attactgaac
      481 ttgacaaaga aaaaattcac gaagatcata tttttcaaaa tataaaaaaa caaggtacaa
      541 ttatagaaac atatgtaagg ctgaaagata atcaaagtgt attttctttt gatagtggca
      601 aaagaattga tgaagcaaac ttgaaaaatt atgttttggt agcagtaaat gggaaagaat
      661 tactcccaga tcacggaatc aaactatcat ctttagtaaa tgggcagcta catccatatg
      721 ttaaagagcc tagtagggca tacgagagtt tgaaggacat aattgaagaa acagaatctg
      781 agccgtttat actctatatc agctcagttt acgatgatat agtttcaaga atagacgaat
      841 ataagatgga ggcaagtata tatgttattg gtctcgtctt atctattgtt attttagcaa
      901 cgttattaaa aatagataaa gaaacatatt tttataatca tggacaacga atagatgttt
      961 ctaggttgtt gggatatgga ttttttgata tacatcataa gaaaattatt ggaaatatcg
     1021 ttggttatat cataagtatt attattttat ttatggttat tatggtaaca ggagtaataa
     1081 gcgatgttgg actgtttata ccaagagatg gttggagtat gtctaaactt ttgattagtt
     1141 taataatagg tatttgtgga agctttatat gttttggcat agaaatttta caactaaaga
     1201 aaagtgaaag aagcattgta cttaggttaa aggagggttg ttaaatgcaa aatgaaaagg
     1261 aattgcaaat aaccttaaga aatgtctcta agaaatatgg agaacacagt attttggaaa
     1321 atattagttt ggatatttat aaaggagatt ttgtttgtat ctttgggaaa agtggaggag
     1381 gaaaaacaac acttttaaat ataattggga cattagaaaa ttatgatagt ggtagtgtaa
     1441 cctgtttttc aaatcgagat cctataaaag ctcctaaagt aggagagcta ttacgcagag
     1501 aaaaaattgc ttatttattt caaaattttg ctttggtgga aaaaatgacg gttgaggaaa
     1561 atatgatgct tgctgcaaaa tacaatcaag aaaaaaataa gaaaaatctt atagaagctg
     1621 ccttgaataa aatgggcatt tcagacaaat taaaatcgaa ggtttatgaa ctttcaggtg
     1681 gagaacagca aagggtagct cttgcaagaa atatgataaa accgtttgaa attatgttgg
     1741 cggatgaacc gacaggttct cttgattatg agaataaaaa aattgtaatc gatacactta
     1801 ttagattaaa tgatgaaggt aagacaatcg tagttgtaag tcatgataag gattttgaaa
     1861 aagtagcaca taagaattat attattgaaa agtcagctat aagggaggtg ttgagatgaa
     1921 aaggaagatt gctttattag taccggttat agtactgtgt atttgtggtt tattctttta
     1981 catgaacaga aatagtgatg atattgatgt tgcatttaca gtaaaaaatg aaacaaaaga
     2041 aaaaatagat acagtgggta ttgcgatggg aaataaatgt attttgaata gaacaaatgg
     2101 agaaaaattt tattttccaa aagacctaat caaagaaaaa caaggcaaag ctattgtttt
     2161 tgtagtatct aaagatggaa tcatagcaaa gtcaggggaa atagatttaa aagaaaataa
     2221 agaagtaagt ataagggaaa taaaagaagg agaaatatcc ttggatatag ctgctcaaaa
     2281 aacagatata aaaattagta ttcctaggtt agatgattgg aaagttagta cagatgaaaa
     2341 atttatcaag ggctcttatg aagcaaatac tgattcgcaa tatacattat atttattagg
     2401 aaaaggcgga aatttaggca tttccggtac ggagatgaaa ggagtacgtg ttattgtaag
     2461 ttgggaaaaa ccaaaagata aaatagatag ttggc
//
LOCUS       DARYMD010000094         2472 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYMD010000094 DARYMD010000000
VERSION     DARYMD010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2472
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            50..1003
                     /locus_tag="TU818_001899"
     CDS             50..1003
                     /locus_tag="TU818_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0924663.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAIRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1063..2262
                     /locus_tag="TU818_001900"
     CDS             1063..2262
                     /locus_tag="TU818_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL0924664.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKQTIS"
BASE COUNT          730 a          440 c          557 g          745 t
ORIGIN      
        1 ggctagtggt attcttttca tttcagcctt attttgatat gatagacgta tgaattttga
       61 aaagattgaa caagcctatg agcttatatt agaaaatagc cagctgattg aaaatgattt
      121 aaaaacgcat atctatgatg ctattgttga gcagaattct ttttatctgg gagcccaagg
      181 agcaagccct caggttgcta aaaatattga gacgttgaag gccttgcagt taaccaagga
      241 ggagtggcgc caggcttatc agtttgtttt gatcaaggct gggaaaacag agccattaca
      301 ggccaaccac caatttaccc cagacgcgat cggctttatc atgctttata ttttggagac
      361 cttgagctca caagagtcac ttgatgtgct tgagattggc agtggaacag gtaatttagc
      421 tcaaactatt ttaaaccact cacataagag cattgattat ttaggcattg agcttgatga
      481 tttactaatt gatctatcag ctagtatcgc tgaaatcatg gggtcatcag cccagtttat
      541 tcaagaggat gctatcagac ctcagctgtt aaaagaaagt gatctcatca ttagcgattt
      601 gccagttggt ttttatccta acgacgatat tgctagcagg tatcaggtgg ctagctcaga
      661 tgagcatacc tatgcccatc atttactgat ggagcaagcc ttaaagtacc tgaaaaaaga
      721 tggctttgct attttcttag caccggtaaa tcttttgagc agcccacaaa gtcacctctt
      781 aaaacaatgg ctgaagggct atgctcaggt tgtggccttg attactttgc ctgaggctgt
      841 gtttggaaat ccagctaatg caaaatcgat tattgttctt tgtaagcaat cgaatcgctt
      901 tgcagaaacc tttgtttacc ccattaggga tttgaaatct gttgataatg ttcgtgattt
      961 tatggaaaac ttcaaaaatt ggaaacggga taatgttatt taagagaatt ttttgatata
     1021 atagaaaagc attgcagaaa acgatttcaa gagaggtaaa acatgtcaaa gacaattgca
     1081 attaatgcag gaagctccag cttaaaatgg cagctatatc aaatgccaga ggaaaaggta
     1141 ttagcacagg gaattatcga acgtatcggt ctgacagact caatctctac tgttaaatac
     1201 gatggcaaaa aagaagagca tattcttgat attccagatc atacagaggc tgttaagcgc
     1261 ttgttgaatg atttgattca ttttggcatt attggtacgt atgacgagat cacaggtgtt
     1321 gggcaccgta ttgttgcagg tggtgaatac ttcaaggaat ctgtggttgt tgatgataag
     1381 gttgttgagc aggttgagga gttagcagcc ttggcaccct tgcacaatcc gggggcagca
     1441 gcaggtattc gtgcctttcg taagattttg ccggacatta cgagtgtttg tgtgtttgat
     1501 acttcgtttc ataccacaat gcaaaagcat acctaccttt atccaattcc tcaaaaatat
     1561 tatacagatt ataaggttcg caagtacggg gcgcatggga ctagccataa atatgttgct
     1621 gaggaagcag caaaaatgct gggtcgccct ctagacgaat taaagctcat tacagcccat
     1681 gttggtaatg gtgtgtctat cacagccaat tatcatggtc agtcagtgga tacctctatg
     1741 ggctttacac cgcttgctgg tccgatgatg gggacacgct ctggtgatat tgatcctgct
     1801 attattcctt atttgattgc tcaggatcct gagctaaagg acgcagcaga tgtggtcaat
     1861 atgcttaaca agcaatctgg attaggtggt gtgtctggta tttccagtga tatgcgtgat
     1921 attgaggctg gcttgcaggc taacaatcca gatgccgtct tagcttacaa tatctttatc
     1981 gatcgtatca agaaatttat cggacaatac tttgcggtat taaatggtgc agatgccttg
     2041 gtctttaccg caggtatggg tgagaatgct cccttgatgc gccaagatgt cgtcaatggc
     2101 ttgtcatggt ttggtatgga aattgatcca gagaaaaatg tgtttggtta tcgtggtgat
     2161 atttcaacag cagcttcaaa ggtgaaggtg cttgtcatct caactgatga agagctgtgt
     2221 attgcgcgtg acgttgaacg cttgaaacag actatatcat aatctgataa tatactctta
     2281 gctcagctga tcagttttaa agagtccaaa aaatactttt aattggtacc gacctccaaa
     2341 agttagactt aaaggtttaa cgattggagg tcggtattat tatatagcca aatattctca
     2401 agacaaagac agccaaaaaa tgagacggtc gtaaccgtct caaaaaagtt taatttaatt
     2461 aaaaacattc at
//
LOCUS       DARYMD010000095         2216 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYMD010000095 DARYMD010000000
VERSION     DARYMD010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(97..1722)
                     /gene="groL"
                     /locus_tag="TU818_001901"
     CDS             complement(97..1722)
                     /gene="groL"
                     /locus_tag="TU818_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL0924665.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TU818_001902"
     CDS             complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TU818_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL0924666.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGDFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
BASE COUNT          626 a          556 c          389 g          645 t
ORIGIN      
        1 agggataatc atatcacctt aacgtcaggg gagtctttat aagttatttt tatatcctat
       61 gacagacaca ctagtctatc ctaacaggcc ttcttgttag aagccaccca tcatgcctgg
      121 atccattcct tgcggcattg ctggtgcagc aggctctggc ttagtggcaa caacagcttc
      181 ggtggtcagg ataagacctg caacagaggc tgcattttga agtgctgaac gtgttacctt
      241 gactggatca atgatacctg tagcaatcat atcaacccat tcaccagttg ctgcattaaa
      301 accaatacca gcagcactat ttttcagctt atcaataatc actgaacctt catagccagc
      361 gttgtaagca atttgacgca caggctcttc aagcgcacga agcacgatat tgcgaccagt
      421 tgctgcatca ccatcaagct caagggctgc aaccttatcc atgacattga taagagcagt
      481 accaccacct gcaacgatgc cttcttcaac cgcagcgcgt gttgcattta gcgcatcctc
      541 aatacgaagc ttcatttctt ttagctcggt ttcagtagct gcacccacct tgataactgc
      601 aacaccacct gctaattttg ctaagcgctc ttgtaatttt tcacgatcaa attcagatgt
      661 ggttgtttct aattgtgatt tgatcaggct aacgcggttt gaaatagctt ctgagctgcc
      721 tgcaccttct acaatcactg tattatcctt gtcaacagtt actttagccg cttgtccgag
      781 ggcagccatt gtagcatcct tcaattcaag accaagatcc tcagtgatga ctgtaccacc
      841 agttaagaca gcaatgtctt caagcatcgc tttacgacga tctccaaagc caggcgcttt
      901 aaccgctaca acattgaagg taccacgaat tttattaagc actagggtcg gaagggcttc
      961 gccatcaaca tcatcagcaa tgatcaacaa tggacggcta gtcttaagca cctcctcaag
     1021 caatggaaga atgtcttgga tattagaaat tttcttatca gtaatcagga taaatgggtt
     1081 ttcaagatca gcaaccattt tttcattgtc agtgaccatg tattgtgaca aatagccgcg
     1141 gtcaaactgc attccctcaa caacctcaag ctctgtttcc ataccacgtg attcctcaat
     1201 agtaatcaca ccatcatttc ccacgcgctc catagcttca gaaatatagt caccaacctt
     1261 ttcagaacgt gatgacaccg aagctacttg agcaatagct tcttttccag atactggttg
     1321 agcaacagcc tttaaggcct cgacagctgt cgttgtcgct gcttcaatcc cacgacgaat
     1381 accaattggg ttagcacctg ctgttacatt tttaagccct tcacgcacaa tcgcttgggt
     1441 caaaacagta gctgttgttg tcccgtcacc agcaatatca tttgtttttg aagctacctc
     1501 tgatacaagc ttagccccca tattttcaaa atgatcttct aattcaatct ctttggcaat
     1561 cgttacacca tcatttgtga tcaaaggaga accaaaggcc ttttcaagga ctacattacg
     1621 ccctttaggg ccaagggtta ccttaacggt atccgccaaa atatcaacac cacgtaccat
     1681 gctttcacga gcatctgctg aaaattttat atcttttgcc atgttatttc ctctattcct
     1741 atttgaatgt atatctgtta atcctacctg aaatgatagg gattcacaat taagctaaaa
     1801 ctgcaagaat gtcagcttca cgacagatga caagctcttg atcgccatct ttaacctcta
     1861 agcctgatcc atattcaacc aaaaccttgt cacctacagc cacacttggt ggaacaatgt
     1921 ctccagtaat agtacgaata cctgtctcac taacagctac aactgtccct actttagtgg
     1981 cttctttgtg actagcagca agaacaaagt caccgacggt ctgctctttt tctgcttcaa
     2041 attttaggac cacacgatct cctaacggtt ttaacatgaa tagtacctcc aataatgact
     2101 agattatcta ttttgttagc actcttgttt tatgagtgct aactttcttc tctattttat
     2161 cacttggtca aaaatagtca agaaaaaaag tctaggaaaa aagaaaagac ccagct
//
LOCUS       DARYMD010000096         2170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYMD010000096 DARYMD010000000
VERSION     DARYMD010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            88..1284
                     /locus_tag="TU818_001903"
     CDS             88..1284
                     /locus_tag="TU818_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0924667.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYH
                     AVIGETDYKKACHAIKAAGYATASDYAELLIQLIEENNLQKWDKEALKTNKEVTMTTA
                     NEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDLWGNAIDLLNSASAQG
                     LEIIYNAPGVNPRAGDLFVMEVAGSPYGHTGAVIEDSDGYTIKTVEQNIDGNWDSLQV
                     GGPARFNTRDFTGVVGWIRLPVDHTKQTVDTAPQTSDTIVETPKTGTFTVDVAEINIR
                     RWPSLASEVVGSYKQDDTVSFDSEGYANGYYWISYVGDSGKRNYLAIGQTDKDGNRIS
                     LWGKLN"
     gene            1419..1961
                     /locus_tag="TU818_001904"
     CDS             1419..1961
                     /locus_tag="TU818_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL0924668.1"
                     /translation="MTEALFVANYIIEYCNDHNLEINNLRIQKLLYFINARNLVENGS
                     PLFQDKIEKWKFGPVVPKVYHEYKRFGASTITKDDISAQIWKFNFEVSPFGEESPIEV
                     LTYNKEEFSDSQIQLIESTILALKKYSTFKLVDLTHEDDMWKSDNQLIMSGEKGLTYD
                     NNEIRDFFMSHIESQIWNNI"
BASE COUNT          707 a          361 c          474 g          628 t
ORIGIN      
        1 agtcttagtc atagtaatcg cagtgctata tttacctgtg tctgtgattg ctctgattgt
       61 ttacccgttt ttagatgagg aggacagatg acctttttag acgacataaa aagcgcagtt
      121 atcgcagagt ggcacaatca taagattttg ccatcgttaa ccgcagcgca ggcaatctta
      181 gagagtggtt ggggcaagta tgccccacat aacgcattgt ttggtatcaa ggcagatagc
      241 tcatggtctg gtaaatcttt tgataccaag acacaagagg agtatcagcc aggtgtcgtg
      301 acggatctcg tggaccgctt tagagcctat gatagttggg acgagtcaat ccttgatcat
      361 ggccagtttt tagtggataa tccacgctat cacgctgtaa ttggagagac tgactataaa
      421 aaggcctgtc atgccattaa agcagctggt tatgccactg caagtgatta tgcagagctg
      481 cttatccagt tgattgagga aaacaacttg caaaaatggg ataaggaagc cttaaaaact
      541 aataaggagg taacgatgac aaccgcaaat gagattgtac aatactgtgt cgacctagcc
      601 aattcaggca tgggtgttga taaagatggc tgttttggga cgcagtgtgc ggacttgcca
      661 tgttttatcg tcaaaaactg gttcggcatt gatttatggg gtaatgcgat tgacctgtta
      721 aatagtgcat ctgcgcaagg gctagagatc atatataatg ctcccggagt caatcctaga
      781 gctggtgact tatttgtcat ggaggtagct ggtagtccct acggacacac gggagctgtt
      841 attgaggaca gtgatggcta tactattaaa accgttgagc aaaatattga cggtaactgg
      901 gatagtcttc aggtaggtgg tcccgctcgc tttaatactc gtgactttac tggtgttgtc
      961 ggctggatta gattaccggt tgatcacact aagcagacag tagatacagc accgcaaacg
     1021 tctgacacta tcgtagagac accaaaaaca ggtactttta ccgtagatgt cgcagaaatc
     1081 aatatcagac gttggccaag cctagcgagt gaagtagtag gtagctacaa acaagatgat
     1141 actgtcagtt ttgatagcga gggctacgct aatggctact actggattag ctatgttggc
     1201 gactcaggca agcgtaacta cctagctatt ggacagacag ataaagatgg caatcgcatc
     1261 agcctttggg gtaaattaaa ttagataaga caaacgccct cgcttttgcg ggggctgttt
     1321 ttattatcaa aatcaatatg tagtgttagc taaaaagtta gctaacaaga tatagtactt
     1381 gacaaatatg ttataattaa aaaaaggagg tggactggat gactgaggca ctgtttgtag
     1441 caaattacat cattgaatat tgcaatgatc acaatttaga aataaataat ttaagaattc
     1501 agaaactttt atactttata aatgctcgga acttagttga aaatggcagc ccactgtttc
     1561 aggataagat agaaaaatgg aaatttggac cggttgttcc aaaagtctat catgaatata
     1621 aaagatttgg agcgtctaca attaccaagg atgatatttc tgctcagatt tggaaattca
     1681 actttgaggt aagccccttt ggagaagaaa gcccaattga agtattgaca tataataaag
     1741 aagaattttc ggattctcaa attcaattaa ttgaaagtac aatactcgca ttaaaaaaat
     1801 atagcacatt taaattagta gatttgacac atgaagatga tatgtggaaa tctgataatc
     1861 aactcataat gtctggtgaa aaaggtttaa cttatgacaa caatgaaata agagattttt
     1921 tcatgtcgca cattgagtct caaatatgga ataatattta gcaaatgaat aatctttatg
     1981 caactattaa taagttaaac aaagtagaac aatctgtttt tttagtaatt aatgacatta
     2041 ttgataataa tactgttttc cctgatgtaa atgctcgcaa tagtttaaaa aaaatagcta
     2101 tttcaacact tggcgatcga acttttagta caccatacga tttcatttct gagcatatat
     2161 ataataatgc
//
LOCUS       DARYMD010000097         2152 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYMD010000097 DARYMD010000000
VERSION     DARYMD010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2152
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            147..548
                     /locus_tag="TU818_001905"
     CDS             147..548
                     /locus_tag="TU818_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL0924669.1"
                     /translation="MAVKRKYIYVKGQKIYVPDEVYRAYKKGLNHETHLKRLDRKHGV
                     FRFGDFNTSIVDIADNTVDVEKIIETKMLIEDLYYALDSLNDEERKLIEALYFDDKTL
                     TEVAKQRDTNPMKISRLRNKILEKLRKFLDK"
     gene            1004..1171
                     /locus_tag="TU818_001906"
     CDS             1004..1171
                     /locus_tag="TU818_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL0924670.1"
                     /translation="MCEEHNIDIKMEIDKKDKQTINQIDGWNIEVKFNENGLSLENLV
                     EEYIKEKFSVY"
     gene            1270..>2152
                     /locus_tag="TU818_001907"
     CDS             1270..>2152
                     /locus_tag="TU818_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019115678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL0924671.1"
                     /translation="MFKDSVNKENIAVMYLRLSKEDGEKTESNSISNQREMINSYAKK
                     NQFIIIKEYVDDGYSGATFDRPNFKEMINDAYDKKFDTIIVKDLSRFGRDYIEAGKYI
                     QRIFPENGIRFISVNDNYDSKSADMNDTHLILPIKNFINDSYCRDISNKVKSSQKIKR
                     EKGDFISAFAPYGYKKSDENKNKLVVDEQAAPNIKNIFDMKLLGYSSKAIADELNHLG
                     VLTPRKYKESQGFKCNGFQNIKGGNWSAKSVNRIIENEVYIGNTLQGKSVTLNYKNKK
                     QIEREKEDWIRVENTHDA"
BASE COUNT          875 a          235 c          411 g          631 t
ORIGIN      
        1 ctttttctag tattagaata tagaacaaat aagactttat attttcattt ttattttaga
       61 ggatcttgca cgtcaaaatg cagaggtcct ccttttttat tcaaaaaata agtttgaaat
      121 ttttgataaa aaggagggct ttacaaatgg cagttaaaag aaaatatatc tatgtaaaag
      181 gtcaaaagat ttatgtacct gacgaagtgt atagagcata taaaaaaggg cttaatcatg
      241 aaactcattt aaagagattg gatagaaagc atggcgtatt tcgttttgga gactttaaca
      301 caagtattgt agatattgca gataatactg ttgatgttga aaaaatcatt gaaacaaaaa
      361 tgctgataga agatctgtat tatgcattag acagtttaaa tgatgaagag agaaaactaa
      421 ttgaagcact atattttgat gataaaactc tcacagaagt tgcaaaacaa agagacacaa
      481 atccaatgaa aatcagtaga ttaagaaata agattttaga aaagctgaga aaatttttgg
      541 ataagtaaat taagtagagg gcagggaaac atctctgtcc tctatttttg aaaatttttc
      601 aaaaatagtg ttaaaagttg tcctgaaagt aaggtttata tatagaggga cttttattac
      661 ctcgttatat atagatttga tctttgacaa ctgaatagac caagacaaga ctttaaccag
      721 tagtggagca atttataaac ttacgccaag ataaacctgc taagttaaat tgatttaaat
      781 gaatacctac atttgtagag gatataaggt ttggagcgat aaataagtct gtataaaaag
      841 agggtggcaa ctcttgtgcg atgatactaa tggggataat gatacttcta cagttgaagc
      901 cggctcatct tgaaaagagg cggaggtgaa attcctatgt agcagccaat gcacttgtca
      961 atgtcataaa acttaaaaat attgaagata aggagaagat attatgtgtg aagaacataa
     1021 tatagatatt aagatggaaa tagataaaaa agataaacag acaataaatc aaattgatgg
     1081 ttggaatatc gaagttaaat ttaatgaaaa tggattgagc ttagaaaatt tagtagagga
     1141 atacatcaaa gaaaaatttt ctgtctatta ggggctgaca aaaaatataa ggagcgttat
     1201 aatatttttg tggaagccta accttggttc gatttattgt atgtaaattg aatttaagga
     1261 ggctttttta tgtttaaaga cagtgtaaat aaagaaaata ttgcagttat gtatttgagg
     1321 ctttcaaaag aagatggaga aaaaacagaa agtaattcta tatccaacca aagagagatg
     1381 ataaattctt acgcaaagaa aaatcaattt ataattatca aagagtatgt tgatgacgga
     1441 tattcaggag caacttttga tcgtcctaat tttaaagaaa tgataaatga tgcttatgat
     1501 aagaaatttg atacgattat tgtaaaagac ctatcaagat ttggaagaga ttatatagaa
     1561 gcagggaaat atatacaaag aatatttccg gaaaacggga taagatttat atctgtaaat
     1621 gacaactatg atagtaaaag tgcggatatg aatgatacac atctaatact ccctataaaa
     1681 aactttatca acgacagcta ttgccgagat atttccaata aagtaaagag ttctcagaag
     1741 ataaaaagag aaaaagggga ttttatcagt gcttttgcac cttatggata taaaaaatct
     1801 gatgagaata aaaataagtt ggtggttgat gaacaagctg ctcctaacat caaaaatata
     1861 tttgatatga agctcttggg atattcctca aaggcaatcg cagatgaatt aaatcactta
     1921 ggtgttttga ctccgaggaa atataaagaa agtcaaggct ttaagtgtaa tggatttcaa
     1981 aatataaaag gtggtaattg gtcagcaaag tcagtaaaca gaattataga aaatgaagta
     2041 tatattggga acaccttgca aggcaaaagt gttaccttaa actataaaaa taaaaaacag
     2101 atagaaagag agaaagaaga ttggataaga gtagaaaata ctcatgatgc aa
//
LOCUS       DARYMD010000098         2089 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYMD010000098 DARYMD010000000
VERSION     DARYMD010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2089
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(207..1721)
                     /locus_tag="TU818_001908"
     CDS             complement(207..1721)
                     /locus_tag="TU818_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0924672.1"
                     /translation="MLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRKAKE
                     YLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYRT
                     KCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEY
                     GFAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQ
                     LTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWND
                     KQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFFRRCLFQLHDLISFQ
                     DYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVE
                     VIIVENKRALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQAPDFVITSDNILPF
                     LEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFHRKHYEQLLEQLLIGDRVE"
BASE COUNT          756 a          412 c          323 g          598 t
ORIGIN      
        1 aaatccactt gaaaggctta tcacaagtgg atttttcaga aatattgtac caaataggca
       61 cgagctattg attgctgcta tttagcatag gtgttatcac gatcagcagt aagccaatca
      121 aaacaggtat cgctaaagca aatcctcaca aaaaatggtc caaagaaaaa cctagcagcc
      181 ttataccact tgcttagcaa aaaaacttac tctaccctat ctccaatcaa gagctgctct
      241 aaaagctgct cgtaatgctt acgatgaaag ttcagaattg attttaccac tgtttttccc
      301 tgctccttaa tgtaatccat gctcatacca attaagacgc tcttatctgg aaatacctgc
      361 tgctcctcaa gaaaaggcaa aatattatca ctcgtaatca caaaatcagg agcctgctca
      421 taattttcca gactatctgt tagcatgttg atacgagtaa tattaacctt ataagaagga
      481 atacttgaga taacaaagta agacaagaca tcacctaatg ctctcttgtt ttcaacgatg
      541 atgacctcta caggcggcaa ggacagctca agcatctgct ccaaatgaag gcacataaaa
      601 tgcaggtgcc ctggtgagag cgtttctgac tggtagctaa ccatcagcca gtccttgatt
      661 tgctcctcaa ccttttctag cagcagctga ctgccttgat acctctttga atagtaatcc
      721 tgaaagctaa tcaaatcatg caattgaaag agacatcttc tgaaaaaggg aagcaaaaaa
      781 tacatctgat cccttaaatg aagctgacga ccaaacaaca tttccaagcg attaacaagc
      841 tccttataca gcggatcttc ttctaagata ttgtagacaa gacgtaattg cttgtcattc
      901 caataatgca taagaaaaga actatcaact gtaagataaa ccaagtaaag ataatctaag
      961 tcaccagaat taaacacaac ctgagtacgt gtctcaattt cttgcttagc atagcaactg
     1021 atttgctcaa aaatagataa ttcttttaaa cgatcaaata aagtaagctg tggtaaggat
     1081 acatcataat tctgcctctt ccaagacagc atgagtaaaa tatcaaaaag ataaaatttc
     1141 ttgtccaaga aaacagtggg ctttaaccgc gtaggggtta aaaaaataaa ggcatgaata
     1201 atttccatat ccttaggtgt catctcataa acagcaaacc catactcctt atgaagcatg
     1261 gcaattaagt agcgaatccg gtactcatcc cctataaccc ggtaatcatc gatatccaaa
     1321 tgaatggatt gcaggtagcc ctttagctta ttgacaagat gataggcctt tgatttggaa
     1381 ataaactgtc ttctgatgaa agttgtcaga cactttgtcc tgtaattatc cgtcaacaga
     1441 aacttcaaca ttttaagcgt atcagatgat gcataaatac tgtgaaaata cttctccttg
     1501 ttattaggat caaactcaca ggtaatgcct gacttcaata cagtaataga caggtctttg
     1561 tcaaatagtg cattaatctg attaaggtat tccttagcct ttcgaggggt tattgacgtc
     1621 tgcgagcaca atgaatcaag tgtaatctct ttttctgtca ataagacagc caatattagt
     1681 tttcgctcaa caatatctct ttctaaatag taatctaaca aaataatctc tctccttatt
     1741 agtttgtatg accatataca ttttagttga taggatttaa aagtcaacta aaaaaaatac
     1801 acaaaaaata acgactgctt cctttcaagg atcatctgaa aatgataaat aaaaaagact
     1861 gaaaatattt tataaaataa cctataagag tatacagtca atagcttata aaatcaagcc
     1921 ttatgataat accttgacaa attagccttt tttagacatt ttatgagaat gtcattttac
     1981 taacataatc agaatattag taacttaatt aaagataaaa aaaccgaaat aaatgcaaaa
     2041 accaagacaa aaatcgccac atgatactac tgtcaactta aagactatt
//
LOCUS       DARYMD010000099         1914 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYMD010000099 DARYMD010000000
VERSION     DARYMD010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1914
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..415)
                     /locus_tag="TU818_001909"
     CDS             complement(<1..415)
                     /locus_tag="TU818_001909"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924673.1"
                     /translation="MSVQVALKKALKPTWKRKLRQSWSIQRSTHLFSWYMVKHMDLTS
                     FRYVETNDYVLPEYGFKIHISGTFQNYKAIFSVVFPYLKCHHISFKYLKDEKMILENV
                     SDMEDPSESGKFITIYPRDREHCKQLLSDLYELIPV"
     gene            complement(831..1697)
                     /locus_tag="TU818_001910"
     CDS             complement(831..1697)
                     /locus_tag="TU818_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL0924674.1"
                     /translation="MQYMGEMFKLLRTSRHISLKEATGDDFSHSMLSRFENGESDITI
                     SKLLVGLSNIRTELNEFIYLANGFKPSPYAVLKQEIWEAISKKDLSSLHQLYTKELEQ
                     YHLYKKDIYFLNALMIKSQMLFLDENIKMTPDEQSFLYDYLFSVEIWGIYELQLFSDI
                     SPLLSLDVYLRYTREMLGRVDFFEELWQHRNLVHSILLNGLFKATQEKRLGIAAYFDK
                     MINNHFFEENDTYLRIVYMIADGQHLYCKGEKELGLKQINDAIHILKALNCDESAAYY
                     SDSLEKWLKEVE"
BASE COUNT          603 a          369 c          266 g          676 t
ORIGIN      
        1 caacaggtat caattcatac aagtcactta ataattgttt acagtgttct ctatctctgg
       61 gataaattgt gatgaatttc ccagattccg aaggatcttc catatcggat acattttcta
      121 aaatcatttt ttcgtctttt aaatatttaa aagaaatatg atgacatttt aaatacggaa
      181 atactacaga aaaaattgct ttatagtttt gaaatgttcc tgaaatatga attttaaatc
      241 catattcagg taaaacataa tcattcgtct ctacatatct aaagcttgtc agatccatat
      301 gcttcaccat gtaccagctg aataaatggg tacttctctg gatgctccat gattgtctta
      361 actttctttt ccacgtaggc ttcaaagctt ttttcaaagc tacttgaaca ctcacgagaa
      421 tcttctttat agatacattt ttaagtaatc attggttttc tcatagcaat acatctcctc
      481 agtcttatta gtataaaact aaaaacgctc acattaacag gtctttttga gcgtttttag
      541 taggactagt tactaaatta tggtttgtag attggacatt tccaagtcac aacaaagcct
      601 ttcactggcg caaagcatct actagcctcg tatgcaaatt gagtcatgtt tgtgatctcc
      661 tttcattctt gatgagtcta gtgtatcatc aaaaaccgta ccaaagctaa actgttcata
      721 tgttcaaatc atggttttga cattaatcaa aaaacagtag ctcaaaaagc cactgtttgc
      781 tactagctaa gcatctaaac cattttgctt atcaatgctt taagttgcat ttattcaact
      841 tcctttaacc atttctctaa actatctgaa taataggctg cactttcatc acaatttaat
      901 gcctttaaga tgtgtatggc gtcatttatt tgctttaagc ctagttcctt ttccccttta
      961 caatataggt gctgaccatc agcaatcata taaacaattc ttaagtaggt gtcattttct
     1021 tcaaaaaaat gattgttaat cattttatca aaatatgcag ctatacctag ccttttttcc
     1081 tgagtagctt taaacagccc atttaataaa atgctgtgca ctaaatttcg atgctgccaa
     1141 agctcctcaa aaaagtctac tcttcctagc atttctcgag tataccgcaa atacacatcc
     1201 aaggataata agggagaaat atctgaaaat aattgtaatt cgtatattcc ccaaatctcc
     1261 actgaaaaca aataatcata taaaaagctt tgctcatctg gagtcatttt gatattctcg
     1321 tctaaaaaga gcatttggct tttaatcatc aaagcattta aaaaatagat atcctttttg
     1381 tataaatgat actgctccag ctcttttgta tacaattgat gtaagctgga caggtctttt
     1441 tttgatatgg cctcccagat ctcttgcttt aggacagcat atggggaagg cttaaagcca
     1501 tttgctagat agataaattc attgagctct gtccgaatat tgctaagtcc aaccaatagc
     1561 tttgagattg ttatatcgga ttcaccattt tcaaatctgc ttaacatcga gtgagaaaag
     1621 tcatctcccg tcgcttcctt taacgatatg tgtcgcgatg tccgcagtaa tttaaacatt
     1681 tctcccatat attgcatatc aatacctctt caatctttca ttttagtata gtatataacc
     1741 ttaaaaatgt aaatccagtc ttgattgcat aaacctttaa ttcaacgttt gatgctacta
     1801 aatatcctat ttttctgaag tagatcctca tctttatgct ataagcactt gctgcgtttt
     1861 agaaaatggg ctaaatcagc tatactcctt tttaataaca aaaaagcctt attt
//
LOCUS       DARYMD010000100         1691 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYMD010000100 DARYMD010000000
VERSION     DARYMD010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1691
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..429
                     /locus_tag="TU818_001911"
     CDS             <1..429
                     /locus_tag="TU818_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0924675.1"
                     /translation="RIDGRNIAEINSESLYKKIAFVQKNDFLVEGNVSDNIKLDGSLN
                     LTDKLKDSLGFDETFLNKKLFRVQSLISEGEKQRIDLARFLNRRYSIYIFDEPTGNLD
                     PARSKAILDYILSIKNAIIIVITHNQDIKTLEQFDEVICL"
     gene            592..1691
                     /locus_tag="TU818_001912"
                     /pseudo
     CDS             592..1691
                     /locus_tag="TU818_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371017.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
BASE COUNT          638 a          180 c          317 g          556 t
ORIGIN      
        1 agaattgatg gaagaaatat tgctgaaatt aactcagaaa gtttgtataa gaagattgcg
       61 tttgttcaaa aaaatgattt tcttgtggaa ggtaatgttt cagacaatat taaattagat
      121 gggagtttga atctaacaga caagctcaaa gatagtttag gatttgatga aacattttta
      181 aacaaaaaat tatttagagt tcagtcttta atctcagaag gagaaaaaca aagaattgat
      241 ttagcaagat ttttaaaccg tagatattct atttatattt ttgatgaacc aactggtaat
      301 cttgatccag ctagatctaa agccatattg gattatattt tatcaataaa gaatgcaatc
      361 atcattgtga ttactcacaa ccaagatata aaaacgttag aacaattcga tgaagtcatt
      421 tgtttgtaaa tgaaaggggg tgatgaacat gattatggaa gattttgaag ttttagaact
      481 agagtttgtc gaagttcgaa atgaacaaac cacaaattgg tattttgttt aatcacaaag
      541 gcatgcaatg agaatttgca tgcctttgta aaatatagaa aggacaataa aatgaataat
      601 ttttttccaa aatggaatca ggataggatt gtatattcat ggcaaaatga taaattaagg
      661 ataggagctg atgataatga tgttctagaa atcaaaggaa actcaatttt ttggtcagat
      721 tttatttctt gttgtgacgg gaataatagt atcaaagaca ttcaaaaact attgaatata
      781 aaatataata tttcagaaga aataattaca gagtatttag ataaattctc aaatcgaaat
      841 ttattggaaa tattggataa tccaataaat caattacagg attataaatc aattgagtcg
      901 ttagaaacat attatgctag tgaaggaatt ggtgggatta aactattaaa aatgttaggg
      961 aatctaaaga tttctattct gggatgtggt ggtggtggat ctcatattgc attacaatta
     1021 gctcaattag gagtgggaag aattcatttg gtggattacg atattgttga agaaaacaat
     1081 atcaacagac aatccatgtt cacatttaac gatgtcggaa attacaaagt tgattgtgta
     1141 gccaaaaata ttcagcaaag aaattctaaa tgtttggtta ccaaaagcac ttctaaaatg
     1201 attaatgtac ctgatgtaaa aaaaagaaat atctgaaagc gattgggtat tctgttgcat
     1261 ggatgaacct ccttatatag cacagaggat tgtaaataga gcatgttatt tattaaaaat
     1321 tccaagtata tactgtttta gccaacgtag tgcggggaaa cttttgtttt gtaatcctaa
     1381 tattgaagat tctggctgta ttgattgttt gttatctgaa caagataatg aaaactttca
     1441 aaagctggtg acaacgttca ctacctataa taggaaattg gtaactgcaa atatcttacc
     1501 aaatatttta ttattgacat cgtgggtggt taaacgatgg ttagattgtg taacagataa
     1561 aaatagtaat gtatggaata tgttgttgag atttgatttt tataaatata tggaagaaaa
     1621 atttcaatat ttttcgaaac aagatagttg tccaacatgt gctaagggtc ttagtacaag
     1681 taaattatgg g
//
LOCUS       DARYMD010000101         1680 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.102, whole genome shotgun sequence.
ACCESSION   DARYMD010000101 DARYMD010000000
VERSION     DARYMD010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1680
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            117..671
                     /locus_tag="TU818_001913"
     CDS             117..671
                     /locus_tag="TU818_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0924676.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
     gene            671..919
                     /locus_tag="TU818_001914"
     CDS             671..919
                     /locus_tag="TU818_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924677.1"
                     /translation="MGKPLLTDDIIEKAQRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            943..1644
                     /locus_tag="TU818_001915"
     CDS             943..1644
                     /locus_tag="TU818_001915"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL0924678.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELV
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAQAAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPDKK"
BASE COUNT          481 a          318 c          439 g          442 t
ORIGIN      
        1 acagtgtggc tatagggcgc agccgtcagg tggtgaagga gggctatgcc aagaggctgc
       61 cacatcaccc aaatcaagca aagtaaaatg atggagagaa agcaaggaga tcagacatgg
      121 attttgaaga aaaaacgatt aaaaggcaag agatttttga tggtcacatt ttcaaagttg
      181 cggtagatga tgtccaattg ccaaacggcc taggtcaggc taagcgcgaa ttgatttttc
      241 atcgcggtgc agtcgctata ttggctgtaa cgccagagcg taagctgtta attgtcaagc
      301 agtaccgtaa ggctatcgaa gcgatttctt atgaaattcc tgctggaaaa ctagaggtcg
      361 gtgaggccaa ctcagcatta gaagcagcag cacgagagct ggaggaagaa accgcctatt
      421 ctggtgattt gcgtcttatt cacgagtttt atacagcgat tggtttttgt aatgaaaaaa
      481 ttaagctgta cttggcgaca gacctgcaga gagttgccaa tcctagacca caggacgcag
      541 atgaggtgat tgagcttctt gagctgagct atcaagaatg tatggatcta gtggcacaag
      601 gaaagcttgt cgatgctaaa accatcattg ccctgcaata ttacgccctt cattttggag
      661 gtgatgtgta atgggcaagc ccttgctgac tgatgacatt atcgaaaagg ctcagcgcgg
      721 agaacagttt gagcctgacg attatgcaga ttttgaaacc aaaatcatga cctttgagga
      781 taagcatact gatcgtattt acaaaagtcg cagaattgaa aatgcaaagc gcagtcgctt
      841 tcaatcgcgg ttaaatctga ttctcttagc ggtgcttgtc ttgattgctc tcttggttta
      901 tgcggtcttt aatttataga aaaaaacaaa taaggatatc atatgaaaat tggaattatt
      961 gcggctatgg aagaggagct gcggttttta ttggagcagc tccacgatag tcaagagcat
     1021 caggtgcttt ccaataccta ctatacaggt cgtcttggtc gccatgagct cgtcttagtc
     1081 caatctggtg ttggaaaggt catgtcagcg atgacagttg cgatgctagc agagcatttt
     1141 caggctgacg ctattataaa tacaggatcg gctggagcaa tagctagtgg cttggctatt
     1201 ggtgatgttg ttgttgctga tcgcttggtg tatcatgatg tggacgtgac ggcctttggc
     1261 tatgactatg gtcaaatggc tgcgcagccc ctttactttg acagtgatag caagctggtt
     1321 gagaccttta agcaggtgct tgatcaggaa aagaccaata gtcggattgg cctgattgca
     1381 acaggagata gctttattgc cggccaagac agtattgata ccatcaaagc acatttccca
     1441 gagaccttag cagtggaaat ggagggagca gcagtggcac aggcagctca agctgctggc
     1501 aagccattta ttgttgttag ggcgatgagt gacacagcgg cccacgatgc taatatgacc
     1561 ttcgatcagt ttattgttga ggctggaaaa aaatcagcca aggtcttgat agccttttta
     1621 gaggccttac ctgataaaaa atgatgacca aaaaaacctg atagcctgtg gtgacagcaa
//
LOCUS       DARYMD010000102         1630 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYMD010000102 DARYMD010000000
VERSION     DARYMD010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1630
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..922
                     /locus_tag="TU818_001916"
     CDS             <1..922
                     /locus_tag="TU818_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL0924679.1"
                     /translation="IEHRVTRDGVMSIINESGDSIKLAIQKAGGIDAKMSAKEIISAI
                     NLNGYGVRISGERIALDGNTTVNGAFGAKLGEFIKLKADQIIGGTIDAAKIRVINLNA
                     SSIVGLDANFIRAKIEHTITSLLEGKVIRARNGAMMIDLSNSKIDFNSNATINFNNKD
                     NALVRKDGTHTAFVHFSHATPKNYTGSALYASIGITSSGDGINSASSGRFCGARFFRY
                     ARGYEHTALVDQAEIYGDDIVFSDDFNIDRGFKMRPSLMPKMVDLNKMYQAILALGRC
                     WLHANNTAWTFNSDTTSAIIREYNSYINGL"
     gene            931..1362
                     /locus_tag="TU818_001917"
     CDS             931..1362
                     /locus_tag="TU818_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL0924680.1"
                     /translation="MDLTVQNKDLNTLYSVLDKIKVTNMRVNRGRAKLLAKVEAKLRE
                     YAKDEVDIIDQYAAKNDKGKWLVDDKGNAKLADVTKVTELNDCLDELANEPIVIKGHE
                     YSKRFIDFLEYLAEAEDEFTGAEIVLIDNILEQYEESKKGE"
     gene            1365..>1630
                     /locus_tag="TU818_001918"
     CDS             1365..>1630
                     /locus_tag="TU818_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL0924681.1"
                     /translation="MARNWKIVGKYPQPNALGVIEGTHVIITGDDGASIPQTIKKDLS
                     STNDLDVIKMVLDEFKKSEYVEIAMGEAVQKVDDLEKLSQDTAKT"
BASE COUNT          518 a          309 c          387 g          416 t
ORIGIN      
        1 aattgagcat cgtgtgacta gagatggggt tatgagtatc atcaacgagt caggcgatag
       61 cattaagcta gcgatccaaa aggctggtgg gattgacgct aagatgagcg ctaaagagat
      121 tatctcagcg attaatctta acggctatgg cgtgcggatc tctggcgagc gtattgctct
      181 ggacggtaat acgaccgtca atggggcatt tggggctaag ctcggtgagt ttattaagct
      241 caaagctgat caaatcattg gtggtacgat tgacgccgct aagattagag tgatcaatct
      301 taacgctagc agcattgttg gcttagacgc taactttatc agagctaaaa ttgagcatac
      361 gattacaagt ttgcttgagg gtaaagttat cagagctcgc aacggagcga tgatgattga
      421 cttgtcaaac tctaagattg actttaacag caacgctacc attaacttta ataacaaaga
      481 caacgctttg gtacgtaaag atggcacaca cactgccttt gtgcacttta gccatgcgac
      541 gcctaaaaac tatacaggat ctgcgctata tgcatctatt ggtattacct cgtcaggtga
      601 cgggattaac agtgcgtcga gcggtcgttt ttgcggcgct aggtttttta ggtatgcgcg
      661 aggttacgag cacacagcgc ttgttgacca agctgagatt tacggtgatg acattgtctt
      721 tagcgacgac tttaatattg atcgtggctt taagatgagg cctagcctaa tgccaaaaat
      781 ggtcgatctc aataagatgt atcaggccat tttagctctt ggccgctgct ggctacacgc
      841 taataataca gcgtggacct ttaactcaga cactaccagc gcaattatca gagagtataa
      901 ctcttacatc aacggattat aggagacaac atggatttaa cagtacaaaa caaagactta
      961 aatacgctct atagcgtact agacaaaatt aaggttacta atatgagagt aaatcgcggc
     1021 cgcgctaagc tgcttgccaa agtagaggct aagctcagag agtatgccaa agacgaggtt
     1081 gatattatcg atcaatacgc tgctaaaaac gacaaaggta agtggttagt tgatgacaaa
     1141 ggcaacgcta aattagctga tgtcacaaaa gtaactgagc ttaacgactg tttagacgag
     1201 ttagccaacg agcctatcgt catcaaaggc catgagtact ctaagcgatt tatcgacttt
     1261 ttggagtatc tggccgaggc cgaagatgag tttacagggg ccgaaattgt actgattgac
     1321 aacattttag aacaatacga agaaagtaaa aaaggagaat aattatggct agaaattgga
     1381 aaatcgtcgg caaatatcca caaccaaacg cgctaggggt tattgagggt acacatgtca
     1441 tcatcacagg tgatgacggt gcatctatcc cgcaaacgat aaaaaaagat ctgtcatcta
     1501 caaatgacct cgacgttatt aaaatggtcc tcgacgaatt taaaaaatca gagtatgtcg
     1561 aaattgctat gggcgaagca gtacaaaaag ttgatgactt ggaaaagttg agtcaagata
     1621 cagctaagac
//
LOCUS       DARYMD010000103         1598 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYMD010000103 DARYMD010000000
VERSION     DARYMD010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1598
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            81..638
                     /gene="efp"
                     /locus_tag="TU818_001919"
     CDS             81..638
                     /gene="efp"
                     /locus_tag="TU818_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL0924682.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            681..1070
                     /locus_tag="TU818_001920"
     CDS             681..1070
                     /locus_tag="TU818_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0924683.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            1063..1515
                     /gene="nusB"
                     /locus_tag="TU818_001921"
     CDS             1063..1515
                     /gene="nusB"
                     /locus_tag="TU818_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL0924684.1"
                     /translation="MTKHFQHSRRDLRERAFQALFAMEMGGDFLPASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTSWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTE"
BASE COUNT          480 a          288 c          371 g          459 t
ORIGIN      
        1 aatggtcata aaacatttga gcctacagct cttttgtggt aaaataagac gataactatt
       61 ttagtaagag gtaataacaa atgattgaag caagcaagct tagagcaggt atgacgtttg
      121 aagcagaagg aaagctaatt cgcgtacttg aagcaagcca tcataagcca ggtaagggaa
      181 acactatcat gcgtatgaaa ttgcgtgatg ttcgtactgg ctctacattc gacacaacct
      241 atcgtccaga cgaaaagttt gaacaggcta ttatcgaaac agtgccggct caataccttt
      301 acaagatgga cgagactgct tactttatga atactgaaac ctatgaccag tatgagattc
      361 cagtagccaa tgttgagcaa gagctattat atatccttga aaactctgat gtgaaaatcc
      421 agttttatgg aacagaggtg atcggagttc aggtaccgac tactgttgag ttgactgtta
      481 cagagaccca gccatcaatc aagggagcaa ctgttacagg ctctggtaag cctgcaaccc
      541 ttgaaacagg actcgtggta aacgttccag actttattga ggtaggacaa aagctaatca
      601 tcaatactgc tgaggggact tacgtttctc gcgcttaatt cgctttccgg aattagtcta
      661 agagaaagaa aggaaatgct atgacaactg aaaatatcgg tgaaattgtt atttcgccac
      721 gagttcttga ggttattacg ggaattgcta cgatgcaggt cgagggtgtt cactcgcttc
      781 acaataaaaa catggcagat acctttaata aagctagtct tggtaagggc gtctatcttc
      841 agacggaaga aaatggaaca gtcaatgcag acatctatgt ttacctgcaa tatggtgtaa
      901 aggttcctgc ggtgtcaatg gctattcaaa gggctgttaa gtcagctgtt tatgacatgg
      961 ctgaggttac catttcttat gttaatatcc atgttgaggg gattgttcct gaaaagacac
     1021 caaagccaga aatgaaatca ttgtttgatg aggatttttt ggatgactaa gcattttcaa
     1081 cattcgagaa gagatttgcg tgagcgtgct tttcaagctt tatttgctat ggagatgggc
     1141 ggagattttc tgcctgcctc acagtttgcc tatgactatg acaaggaagc agctgatgac
     1201 aagcagcctt ctgagcttcc tgtttttctg ttaaatcttg tcaatggcgt tatggatcat
     1261 aaggctgagc ttgatgaggt tatcaagaaa aaccttaaaa cgagctggtc cattgagcgc
     1321 ttgacagtgg tagacaagac gatgttgcgt cttgggctct ttgagatgac cctgtttgag
     1381 gagacacctg atcgtgtagc cttaaatgaa atcattgaaa ttgctaaaaa atattctgat
     1441 gatacctcag ctaagtttat taatggctta ctcagtcagt ttgtttctga tgagtcagct
     1501 gcagtgacag aataacaagc tggtgaaagc ttcttaagtt actaaagccc tatagggctt
     1561 tttgaatgct caaaaacgtc tcatctggtt ggctatgt
//
LOCUS       DARYMD010000104         1503 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYMD010000104 DARYMD010000000
VERSION     DARYMD010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            71..1468
                     /locus_tag="TU818_001922"
     CDS             71..1468
                     /locus_tag="TU818_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL0924685.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENIAYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGELIQMEASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEVHGIPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITSISQANRYLKRWIKRFNKQFGGLASESVFEKAPK
                     PAQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKKIYFTRKTKALVIEAFDGDIYL
                     NIADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKS
                     YEEFKRERNTSQPQL"
BASE COUNT          530 a          300 c          299 g          374 t
ORIGIN      
        1 gtcttagcta ggtcgaatgt gaaaatgtcc cgtctgttaa actagaaaga tgaggaaaat
       61 agaactaact atgatagagt caaagaaata cctagtcatc aaagctgttt gtgagggtaa
      121 aaaacagaaa aacagggctt gtgtagaatt agggttaagc aagaggcagg tgaaccgatt
      181 gatactagcc tatcgagaga aaggaaagtc agctttcgtt catggtaata gatcaaaaag
      241 accaactcat gccatgtctt tagaaacaaa gagaaggatt atcgagaaat atcaaagtta
      301 cggtgattta agaccaaatg ttgttcattt ctgcgaacta ctagcggaag aagaaaacat
      361 cgcctattca gatacaactg ttagaaaact actctaccaa gcagggtttc tatctccaaa
      421 gactcaacga gcaacgaaaa gacgattgaa acaagaagcc aaacaaaaga aaagggaggc
      481 agaaaaaaga ggatccaaac tcccaactgc ttccaacttc tttgaagaac ctgacaaagc
      541 tcatcccagc cgagcaagaa agaaattcaa aggggaactc attcaaatgg aggccagtca
      601 attcccttgg tttggacaac aggaaacaca tcttcatgtc gctattgacg atgcctccgg
      661 tgatattgtc ggggcttact ttgatactca ggagacgcta aacgggtatt atcatgtctt
      721 agaacagatt ctagaggtac atggtatccc tttccagttc cttactgata aaaggactgt
      781 attcacttat gcttccagtc agtctaaaaa gatcgaggaa gataccttta cacagtttgg
      841 atatgcttgc catcagcttg gtattgccat tgaaacgtct tctatccctc aagctaaagg
      901 gcgtgtagaa cgtcttaatc agacccttca atcgcgtcta ccaattgatt tacagaggaa
      961 tcaaattacc agcatctctc aagcgaatcg ttatcttaag agatggatta aacgatttaa
     1021 caagcagttt ggtggactgg ccagtgagtc tgtttttgag aaagcaccta aaccggccca
     1081 gcgaaaccta ctgttagcga gaatctctga aagagtaatt gatagtgggc atcatattcg
     1141 atatcaaaac aacttctact tgcccgtcga aggggataaa aaaatctatt ttacgcgtaa
     1201 gacaaaggca cttgtgattg aggcattcga tggagacatc taccttaata tcgcagacaa
     1261 tatttatgcc actagaaagt taccaaaaca cgagaagcac tccaaagaat tcgaaatggt
     1321 gcctaaaact aaaaaagaaa gacgcaagta tattccacca caatcccatc cgtggaaact
     1381 tgcatctttc aaacaatacc ttcataaaat cggaaaatct tatgaagaat tcaagcgtga
     1441 gaggaatacc tctcaaccac aattataaca gatttttctc ttatctaacc gattttttca
     1501 aga
//
LOCUS       DARYMD010000105         1503 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYMD010000105 DARYMD010000000
VERSION     DARYMD010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            46..414
                     /locus_tag="TU818_001923"
     CDS             46..414
                     /locus_tag="TU818_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL0924686.1"
                     /translation="MANRTRNNGIYLMLSDDELEILNKKYELSGCKSLRQFIMKCILE
                     KDIFVLDMKVFKEMSTNIGRITGSINQIAKRVNSTAVIYKDDINDLKKLLEKQGKDIY
                     FLRKKLYELGNFGTSGTEEI"
     gene            414..>1503
                     /locus_tag="TU818_001924"
     CDS             414..>1503
                     /locus_tag="TU818_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL0924687.1"
                     /translation="MAVTKIHPIEKTLYLALDYIMNEDKTDEKILISSFGCNPKTAHL
                     EFEHTKKECNSKAKILARHLIQAFAPGETTPEQAHQIGLDLCERVLRGKYEYVLTTHI
                     DKGHLHNHILFNNVSFETGKAYQSNKRSYHQIRTVSDDLCRENGLSVIDENYKKFKNR
                     YSTNGKTYMEYTEFKKGNSWKNKLQLTIDKAVLKSKTYEEFLKTMEDFGYEIKIGKYL
                     SFRHKDKRDKGRFTRAKASTLGEDYTKERIKERIEDSNKQNIYVNQEYHYEKRSYKKP
                     DTIVDMKNNEKVKSSKGYEVWAGKHNMKTMASALNEMRKSGINSYEELDLKLKKVASD
                     RQQLLDHIKQIEKEMKSIYSVIENKNTIS"
BASE COUNT          621 a          211 c          271 g          400 t
ORIGIN      
        1 ttcttttgta aacttttaat acatctatga attggaggtt atactatggc aaacagaaca
       61 agaaataatg gaatatacct tatgctttct gatgatgaac ttgaaatttt gaataaaaaa
      121 tatgaactgt ccggttgtaa aagtttaaga cagtttatta tgaagtgcat ccttgaaaaa
      181 gatatttttg tactggatat gaaagtgttt aaggagatgt ctacaaatat cggaaggatt
      241 acaggtagca tcaatcagat tgcaaaaagg gtaaattcaa ctgctgtaat ttacaaagat
      301 gacatcaatg atttgaaaaa gctcttggaa aaacaaggaa aagacatcta ctttcttcgt
      361 aaaaagctat atgaattagg gaattttgga acaagtggta cggaggaaat ctaatggcag
      421 ttacaaaaat tcatccgata gaaaaaacac tttatctagc attagactat attatgaatg
      481 aagataaaac cgatgaaaaa atccttatct cctcttttgg ctgcaatccc aaaacagccc
      541 atcttgaatt tgaacataca aaaaaagaat gtaattccaa agcaaaaatc ttggcaaggc
      601 atctaattca agccttcgct ccaggagaaa ctacacctga gcaggcacac caaatcggac
      661 tggatctatg tgagagagtc ttgaggggaa agtatgaata tgtccttaca acacatatcg
      721 acaaggggca tctacacaat catattctgt ttaacaatgt cagctttgaa acaggaaagg
      781 catatcaaag taataagaga agttatcatc aaatccgaac ggtcagtgat gatttatgta
      841 gagaaaatgg cttgtcagtt attgatgaaa actacaaaaa atttaaaaac agatactcta
      901 caaatggtaa aacctatatg gaatataccg aatttaagaa aggaaactct tggaagaata
      961 aactacaact tactattgat aaagctgttt taaaatccaa aacttacgag gaatttctaa
     1021 agacaatgga ggatttcggt tatgaaatca aaataggaaa atacctttcc ttccgacata
     1081 aagataaaag agataaggga agatttacca gagcgaaagc atctacttta ggggaagatt
     1141 atacaaaaga gagaatcaag gaacgaatcg aagattcaaa taagcaaaat atttatgtta
     1201 atcaggaata tcattatgaa aaacgctcct acaagaaacc ggatactatt gtagatatga
     1261 aaaacaatga aaaggtaaaa tcatctaagg gatatgaagt atgggcaggt aaacataata
     1321 tgaaaactat ggcatctgcc ttaaatgaaa tgagaaaatc aggtattaac tcctacgagg
     1381 aattagattt aaaattaaag aaagtggcat cagatagaca acaattattg gatcatataa
     1441 agcaaataga aaaagaaatg aagtccattt attctgtaat agaaaataaa aatacgattt
     1501 ctg
//
LOCUS       DARYMD010000106         1441 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYMD010000106 DARYMD010000000
VERSION     DARYMD010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1441
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..317
                     /locus_tag="TU818_001925"
     CDS             <1..317
                     /locus_tag="TU818_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HEL0924688.1"
                     /translation="RGDVLLRKFKAESNKINGQIKTIKNELKVVDDKKRSIKRRKDEL
                     KKFIEALFYCLEDYKSIEVDKELVDTLINRIEISKYKQVTIYFKFSFDKDIEKQLEVE
                     HE"
     gene            310..>1441
                     /locus_tag="TU818_001926"
     CDS             310..>1441
                     /locus_tag="TU818_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL0924689.1"
                     /translation="MNRIAIYLRLSEEDYKKTDESVSIVNQRDYVRNYIENENSLKDC
                     EIEEYIDDGFSATNTNRPSFLRLIDNIKAGRINTIIVKDMSRFSRDYILLGDYLSNIL
                     PFLKIRFIAINDNYDSINEDGNGIDTDIQFKTLYYDLFSKELSEKVKSSFKQLKSQGK
                     NTNWAAPFGYIKDPKDKHHIILDEKTAFIVKEAFDLLLEGYSCNQVANIFNEKDYITC
                     SERKEELKISEYTRNLVTGSKINKRVWTSATISRITSNELYTGDYVYNKYKETKMGGR
                     KRILLPEEEWEIIHNTHEAIVSREVFDKVRIIKKKRIFGGYAKNREESVFSDKIFCKE
                     CGRHMGFRCDSRQKKNPNKVYKYRNYYCYFCKASRTPNNVKER"
BASE COUNT          615 a          146 c          278 g          402 t
ORIGIN      
        1 ttagaggaga tgttctttta aggaaattta aagcagaaag taataaaata aatggacaga
       61 taaaaacgat aaaaaatgaa ttaaaggtag tagacgataa aaagaggagc ataaagagaa
      121 gaaaagatga actcaaaaaa ttcatagaag ccctatttta ctgcttagag gattacaaga
      181 gtatagaggt ggataaagaa ctggttgata ccttaattaa ccgtatagaa atctcaaaat
      241 acaagcaagt aactatatac tttaaattta gttttgataa agatatagaa aagcagttgg
      301 aggtagagca tgaatagaat agccatttat ttaagacttt cagaagaaga ttataaaaaa
      361 acggatgaaa gtgtaagtat agtaaatcag agagactatg taagaaatta cattgaaaat
      421 gagaactctc tgaaggattg tgagatagaa gaatatatag atgatggttt ttctgctaca
      481 aatacaaaca gaccttcgtt tttaagactt attgataata taaaagctgg gagaataaat
      541 acgataattg taaaggatat gtcgagattt tcaagagatt atatattgct tggagactat
      601 ctgagtaata tattgccctt tttgaaaata cggtttattg ctatcaatga taactatgat
      661 tcgataaacg aagatggaaa cgggatagat acagatatac agtttaagac cttgtattat
      721 gatttattca gtaaggaatt atcggaaaaa gtaaaaagtt cttttaaaca actcaaatca
      781 cagggcaaga atacaaattg ggcagcacct tttggatata taaaagatcc aaaagataaa
      841 catcatatta tacttgatga aaagacagct tttatagtga aagaagcttt tgacttgctg
      901 ttagagggat attcttgcaa tcaggtagca aatatattca atgaaaaaga ttatataacc
      961 tgttctgaaa gaaaagaaga actaaaaatt tcagagtata caagaaatct tgttactggt
     1021 agtaaaataa ataaaagagt ttggacaagt gcgactatat ccagaataac gagtaatgaa
     1081 ttatatacag gagattatgt atataataaa tacaaagaaa ccaaaatggg aggaagaaaa
     1141 agaatcttgc ttcctgaaga agaatgggaa ataattcata atactcatga agcgattgtt
     1201 tctagagaag tttttgataa ggtaaggata ataaagaaaa aaagaatttt cgggggatac
     1261 gcaaaaaaca gagaagaatc tgttttttct gacaagattt tttgtaaaga atgcggtaga
     1321 catatgggat ttagatgtga tagtaggcaa aagaaaaatc caaataaagt gtataaatat
     1381 agaaattact attgttattt ctgtaaagct agtagaactc ccaacaatgt caaagaaaga
     1441 g
//
LOCUS       DARYMD010000107         1434 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYMD010000107 DARYMD010000000
VERSION     DARYMD010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1434
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            110..493
                     /locus_tag="TU818_001927"
     CDS             110..493
                     /locus_tag="TU818_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL0924690.1"
                     /translation="MKKALSLVLLTGLMLASSVPAFAAEETNLPYVEGLGYEVEVFEE
                     DYTQPKLFSYDSGWKSFLGGKWRHGVGSRYVWSKYDHNNKTHKTTVQGAGGQFSYSGW
                     TSAGSRAEASWEKALSGNRAWADVK"
     gene            601..>1434
                     /locus_tag="TU818_001928"
     CDS             601..>1434
                     /locus_tag="TU818_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924691.1"
                     /translation="MKKTVGILAILLIIVIGIGKFFYSDGMFLNIFIKEFNTTVNIVT
                     KPEIADKTIIELQKIANKNDLSFIKEEYIPKNSRFDKQKMKIYIHLNDSEWFKKSFRN
                     ISIADSKDKLNDFENVKSMSLLTSKDISLIPFENVNKEKVNGDYHVRGTEENINKFIE
                     EINQNEKLKTEVVVNPDFIVSSEFTQKQAYLYMLTIFIIFVATVFCLIIYNGMLSKEL
                     SISILLGCDELTLAIAKVLNILAIPAIVGLVLTIGIIEYLVAPSDILGFMISMKTILI
                     LV"
BASE COUNT          531 a          157 c          281 g          465 t
ORIGIN      
        1 caataatcct cataggtata ggaacggaga ttgagtagag ttttgggaaa ctttattcgg
       61 aagaaaaatt ttacaaaaaa tttaagtatt tgagagagga gaatttatca tgaaaaaagc
      121 attgtcatta gtattattaa caggtttgat gttagcatca tctgtaccag catttgcagc
      181 agaagaaaca aacttgccat atgttgaagg tcttggttat gaggtggaag tatttgaaga
      241 agattatact cagccaaagt tgttcagtta tgatagcgga tggaaaagtt ttttaggtgg
      301 aaaatggaga catggtgtag gtagtcgata tgtttggtct aaatacgatc acaataataa
      361 aacacataaa actacagtac aaggtgctgg tggtcaattc tcttattcgg gttggacaag
      421 cgctggaagt agagcagaag cttcttggga aaaagcttta agtggtaata gggcttgggc
      481 tgatgttaaa taacaataaa taaaaaatag ttgaacgagt ttgagcggtg ccacgttgtt
      541 attttagcat tgtggcatta ctcatactcg ctatttttat aaagttggag atgatacaga
      601 atgaaaaaaa cagtgggtat attggcaatt ttactaatta tagtgattgg tataggaaag
      661 tttttctatt cagacggcat gtttttaaat atattcataa aagagtttaa tactactgta
      721 aacattgtaa caaagccaga aatagctgat aaaacaataa ttgaattgca gaaaatagct
      781 aataaaaatg atttaagctt cataaaggaa gaatatattc ctaagaatag tagatttgat
      841 aaacaaaaaa tgaagattta cattcatcta aatgattctg aatggttcaa gaaatctttt
      901 agaaatatat ctattgctga tagcaaagac aaattgaatg attttgagaa tgtaaaatca
      961 atgagtttgc tgacatcaaa agatataagc ttaattcctt ttgaaaacgt caacaaggaa
     1021 aaagttaatg gggattatca tgtaagaggg acggaagaaa atattaataa gtttattgaa
     1081 gaaataaatc aaaatgaaaa attaaaaaca gaagtcgtgg ttaatccgga ttttattgtt
     1141 tctagtgaat tcacacagaa acaagcatat ctatatatgc ttacgatttt tattatattt
     1201 gtagctactg tcttttgtct aattatttat aatgggatgc tttcaaagga attatcgata
     1261 tcaattttac taggatgcga cgaattaact ttagctattg ctaaggtttt aaatattctt
     1321 gcaataccag caatagtggg acttgtactg acgattggaa ttatagaata tttagttgct
     1381 cctagtgata ttttaggatt tatgatatca atgaaaacaa tacttatttt agtt
//
LOCUS       DARYMD010000108         1405 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYMD010000108 DARYMD010000000
VERSION     DARYMD010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1405
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..729)
                     /locus_tag="TU818_001929"
     CDS             complement(<1..729)
                     /locus_tag="TU818_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEL0924692.1"
                     /translation="MGMWFEYVNKEMENTKASLFVFPFAGGGVSSFRRWGNQFKDINL
                     FVAQYPGRENRFSEKAISNIEELVKGLFEDLKMTFDFNSPYYFFGHSMGTKIAYELAL
                     KIKENGLPNPNGIIISAGRAPCYKEPNPIYHLDDEGFIEGLRRYDGTPNEILDNKDLI
                     GIFLPTLRADFIIDEDYQDTKGEKLNSKILGLMGDIDEEMELEELLKWQDYTTKEFSY
                     RYINGKHMFVNTSPESVIKAIEEFV"
     gene            complement(958..1338)
                     /locus_tag="TU818_001930"
     CDS             complement(958..1338)
                     /locus_tag="TU818_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012797113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL0924693.1"
                     /translation="MNKIYHKEYVEQNYLENIYTLYLERDEVRNIDIVDKLGVARATV
                     THMLRNLEKKGYIKYGDDKIVRFTSKGRTLAVELYEKHIYLTQVFKHIGVDEKIAEIE
                     ACQIEHIISKDTFNKIKKYFEDKI"
BASE COUNT          444 a          273 c          139 g          549 t
ORIGIN      
        1 aacaaattct tcaattgctt ttatcacact ttcaggagat gtatttacaa acatatgctt
       61 gccattaata tatctgtaag agaattcttt cgtcgtataa tcttgccatt ttaaaagttc
      121 ttcaagttcc atttcttcat caatatcacc catcagacct aaaatcttgc tattcaattt
      181 ttcccctttt gtatcctggt agtcctcatc gataataaaa tcggctctta gtgttggtaa
      241 aaaaatccca atcaaatctt tattgtctaa tatctcattt ggagtaccat catatcttct
      301 taacccttca ataaatcctt catcatctaa atgataaatc ggattcggtt ccttatagca
      361 aggggctcgc ccagctgata tgataattcc attcggattt ggtaacccat tttctttaat
      421 tttcagagcc aattcataag caatcttagt tcccatacta tgcccgaaaa aataataagg
      481 tgagttaaaa tcaaaagtca tttttaagtc ttcaaacaat ccttttacaa gttcttctat
      541 gttgctaatt gctttttcag aaaacctgtt ttctctccct ggatactgtg caacgaagag
      601 atttatatct ttaaattgat taccccatct tctgaatgat gatactccac cacctgcaaa
      661 tggaaacaca aataaactag ctttcgtgtt ttccatttct ttattaacgt attcgaacca
      721 cattcccatc aaaacacctt ccatctgatt attaatatac tactagaact attattgtta
      781 gatacatcta acaataatag tttaatcctt ctaacataaa aagtcaatac atttacactg
      841 ttttatagtt atattttcta tatctaaaag gcttgaagaa actaagttat atacctttta
      901 taattatcaa aaaataaaga acatacaatt ttaaaaatta attgcatgtt ctttctctta
      961 tatcttgtct tcaaaatatt ttttaatttt attgaaagta tcctttgata ttatgtgttc
     1021 aatttgacag gcttctattt cagctatctt ctcatctaca ccaatatgtt taaaaacttg
     1081 tgtcaaatag atatgttttt catataactc gactgctaaa gtccttccct ttgatgtaaa
     1141 tctaacaatt ttatcatcac catatttaat gtaacccttt ttttcaagat ttctcaacat
     1201 atgtgttaca gttgctcttg caaccccaag tttatctact atatctatat ttcttacttc
     1261 gtctcgctct aagtatagag tataaatatt ttccaaataa ttttgttcta catattcctt
     1321 atgatatatt ttattcataa actcatctaa cttatccctt ctaattattc tttaaatcaa
     1381 cattcttatt attgttatac tactt
//
LOCUS       DARYMD010000109         1325 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYMD010000109 DARYMD010000000
VERSION     DARYMD010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1325
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..1144
                     /locus_tag="TU818_001931"
     CDS             <1..1144
                     /locus_tag="TU818_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL0924694.1"
                     /translation="KYDQTTLENMGENEKQVGIKADKEAISKFTSLTLNGKKYTDKKQ
                     AGEFLINKIKGIKKLDDFRSEEVKIGEYRNFDLFAYYDRFSNQYKFNLKGEENHYGEF
                     GTDEIGNITRMDNVLDRMPERLEQTLGKLKDTENQLETAKLEIKKKFPQAELLKEKTL
                     RLAEVNNLLDMGQKGDLKEEKNPLLEEVKEELIHFLNKEYDEAHSIEDFDTMFPDLTD
                     IGLAYTTTPDEKHEIQTSLDLINYKMNTYVDNTLIDSFQYTYDPLNASDTKELIQIKT
                     NIGFWDFNELVYVDEEKLKASLGLEIDDDGNFYDPLSKDMDLDGVMDRYDADFRDSKV
                     QSFGDLDKKEKASVMDRLGYFKEKIKKGGLQNENIDRKIECKEEVR"
BASE COUNT          551 a          156 c          278 g          340 t
ORIGIN      
        1 aaaatatgat cagactactt tagaaaatat gggtgaaaat gaaaaacaag tggggataaa
       61 agcagataaa gaagcaatat caaaattcac atctttaact ttaaatggga aaaaatatac
      121 cgataaaaag caagccggag agttcttaat aaacaagata aaaggaataa aaaaattaga
      181 tgattttcgt tctgaggaag taaaaatcgg agaatataga aatttcgatt tgttcgcata
      241 ttatgacagg ttctccaatc agtataaatt caatctgaag ggagaagaaa atcattatgg
      301 ggagtttgga acggatgaaa tcggaaatat cacccgaatg gataatgtac ttgataggat
      361 gcctgagaga ttggagcaga cacttggaaa acttaaagat accgagaatc aacttgaaac
      421 ggcgaagctt gaaataaaaa agaaatttcc acaggcagag cttttaaaag aaaagacgtt
      481 aagacttgct gaggtaaata atttgcttga tatgggacaa aaaggagatt taaaagagga
      541 gaaaaatcca cttttggaag aagtgaagga agaactgatt cattttctaa ataaagaata
      601 tgatgaagca cacagtatag aagatttcga tacaatgttt cctgacttga cagatatagg
      661 tttggcatat acgactacac cggatgaaaa gcatgagata cagacaagtc ttgatttaat
      721 caattacaag atgaacactt atgtagacaa tactttaatt gacagttttc agtatactta
      781 cgatccactt aatgcaagtg atacgaagga acttatacaa atcaaaacga acataggttt
      841 ttgggatttt aatgagctgg tatatgtgga tgaagaaaag ttaaaagcat cacttggact
      901 tgaaattgat gacgatggta atttctatga tccgctttca aaggatatgg atttagatgg
      961 agtaatggac aggtatgatg cagactttag agatagtaaa gtacaaagtt ttggagattt
     1021 ggataaaaaa gaaaaagcat ccgtaatgga taggcttgga tacttcaaag aaaagataaa
     1081 gaaaggaggc ctacaaaatg aaaatattga tagaaagata gagtgtaagg aggaggttag
     1141 atagttggaa tatcacaaaa atattagagc aacggataga gaaatgcaga aactttttga
     1201 aaatgaggag tataactatt ccgtaagata ttttgaaaaa atagaagaaa acttatttaa
     1261 aacgataatt cgcacaccgg agaatataga gtttccaaaa tccaaaacct tgtctataaa
     1321 cacga
//
LOCUS       DARYMD010000110         1316 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYMD010000110 DARYMD010000000
VERSION     DARYMD010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1316
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(146..538)
                     /locus_tag="TU818_001932"
                     /pseudo
     CDS             complement(146..538)
                     /locus_tag="TU818_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
     gene            complement(535..1062)
                     /locus_tag="TU818_001933"
     CDS             complement(535..1062)
                     /locus_tag="TU818_001933"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL0924695.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LVTYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RCTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
BASE COUNT          423 a          330 c          254 g          309 t
ORIGIN      
        1 ggtaaagcac tagaaagcac tcaacagcag acaaaatagg agttggggca accgtcctag
       61 aagcattaaa aagcaacagc agcaaaaccg ttgctttttg tttaaatcaa agatacacct
      121 gtcctagcac ttataagctt gaaggaaaaa gaccaaaaag agaggtggaa gcacctgctg
      181 ctacggtatc tggtgtcagc cacatgataa aagcattccc cataatccct gaacacacat
      241 acagcagcaa aaactgtctt gacccccaaa tggtctcagc catccgcccg acaaaataaa
      301 gggttaaggt attaatgaaa aaatgctcaa agccaatatg aaccactata ggtgtcacca
      361 agcgccaaag ctgatcaggc attgctctga caacaagacc attcatgcca ccaaatataa
      421 caacagcata agggtgcgta gcaaactggc catagaccag ctgcattatc aaaaaaacta
      481 aaccagtcaa gcccaagaaa aagagtgtta tcgggtattt tttgatcatc agtctcattg
      541 gcaatacacc tccttcacag caatatcatg tgcctctacc acaaaatcct cccactgaca
      601 ggcataaatc gtgctaaagg tagccccctg ataatccctc aaataacgat catagtagcc
      661 accaccatag cctatacgat agcctgcagg gtgaaaaaca agccctggca catgaatggc
      721 atcaatctcc gacttagcaa cagctatggt acacctaggc tccataagac caaaagccgt
      781 ctgtatcaag tcacaaggat cataagccac aaacaccatc tctccacgag aacgagtctt
      841 gggcacaagg atagtcttgc cgtcctgcaa ggctcgctca atcagtagat ggctttgata
      901 ctcgtgtggc aagggcagat aggtcacaag agtctgcgcc tcttgatagc tgctactagc
      961 aactactgct gccaatagag ctaagtcctt ttccagctta tcctctgggg tcatcatggc
     1021 taggcgctga agcactagtt ggcgataatc ttttttaatc atgcccatat cataacacaa
     1081 agcgctgcta ctattcaaga atcggccaca atcaaggttc tttccttagt tgtcctacca
     1141 gacagggcag cagctcaatc agtgaatgtc cttcttactt cttgaggtga gcttgtggtc
     1201 tcatgagatc aaaaaattat ttttctaggt taagaaaagt ttaagcttta tgctatacac
     1261 ccgactttat cacttgtttt agtccacacc ttactcaacc ccttggtaga gtaagg
//
LOCUS       DARYMD010000111         1299 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYMD010000111 DARYMD010000000
VERSION     DARYMD010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1299
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..>1299
                     /locus_tag="TU818_001934"
     CDS             <1..>1299
                     /locus_tag="TU818_001934"
                     /inference="COORDINATES: protein motif:HMM:NF012873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924696.1"
                     /translation="SLDIDELPLTEIQSAYLLGRRNHFELGGVASHVYMEVILPLLDI
                     DRAEKVWNDIILKHDALHSIFTSNNTQKVLKEFAYYKIECNEGADIKEKIALTRDKLK
                     GKSYNADIWPLFDISVSQLDDNSLLHLSFDFLILDWASIWILLKEFEECYFDGKTIMD
                     NSYDLKEIRTSQLKLKHSSKYLSDKDFWERRIPFLPDAPLLPIKNKIVKNGFERIQLR
                     IDENTWSKIKSNISEIGVTQTSFLVTILALVLNRWSSNSEFTINLTTMNRPKEYIKSD
                     VVNDFTSTELLEFRMESLQPFYVLLKHIQQQMIEDLQHETFTGVEVTREVRKNVERRD
                     AIFPFVFTSALGIKASEYKYISLQKEGLSETPQVLMDCQVMEVNHELIINFDLRADAF
                     SKELSNSIAEDYSNLLNCFFDLEYFKKTLTEMYDENEMNDV"
BASE COUNT          496 a          150 c          232 g          421 t
ORIGIN      
        1 ttcactagat attgatgaat tacctttaac agaaattcaa agtgcatatt tattaggtag
       61 aagaaatcat tttgaacttg gtggtgttgc cagtcatgtt tatatggaag taatattacc
      121 tctattggat atagatcgag ctgaaaaggt ttggaatgat ataatactaa agcacgatgc
      181 attacattca atatttacat caaacaatac tcagaaagta ctgaaggaat ttgcttacta
      241 taaaatcgaa tgcaatgagg gtgcagatat aaaagaaaaa attgcattaa caagggataa
      301 acttaagggg aaaagttata atgcagatat atggccacta ttcgatataa gtgtaagtca
      361 gttagatgac aatagtttat tgcatttatc atttgatttt ttgattttag attgggcaag
      421 catttggatt ttattaaagg aatttgaaga gtgttatttt gacggaaaga cgattatgga
      481 taattcttat gatcttaaag aaataagaac gagtcaactt aaactgaaac atagttctaa
      541 gtatttatcg gataaagatt tctgggaaag aagaattcct tttttgcctg acgctccact
      601 attaccaatt aaaaataaaa tagtcaaaaa tggttttgaa agaatacaac ttagaataga
      661 tgaaaatact tggtcgaaga taaaatctaa tataagtgag attggtgtca cgcaaacatc
      721 tttcttggtg acaatattag ctcttgttct taatagatgg agttctaatt ctgaatttac
      781 cattaattta acaactatga atagaccaaa ggagtatata aagagcgatg ttgttaatga
      841 ttttacatct acagaacttt tagagtttag aatggaatct ctgcaaccat tctatgtttt
      901 attaaaacac atacaacagc aaatgattga agatttgcaa catgaaacat ttacaggagt
      961 ggaagttact cgtgaagtta ggaaaaatgt agaaaggaga gatgctatat ttccatttgt
     1021 tttcacaagt gcattaggaa taaaagcttc agaatataaa tatattagtt tacaaaaaga
     1081 aggtttgagt gaaactcctc aagtattaat ggattgtcaa gtaatggagg taaatcatga
     1141 actaataatt aattttgact taagagcaga tgctttttca aaagaattat caaattcaat
     1201 tgcagaagac tattctaatc tattaaattg cttttttgat ttagaatatt tcaaaaaaac
     1261 actgacagaa atgtacgatg aaaatgagat gaatgacgt
//
LOCUS       DARYMD010000112         1288 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYMD010000112 DARYMD010000000
VERSION     DARYMD010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            85..1288
                     /locus_tag="TU818_001935"
                     /pseudo
     CDS             85..1288
                     /locus_tag="TU818_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISSeq1 family transposase"
BASE COUNT          392 a          309 c          242 g          345 t
ORIGIN      
        1 gggttatagg gctttatgag tatcaaaaaa gtcccatatg acctataatg aaaagcgact
       61 aaactatcat ttagaaagac tcatatggaa caatcacatg ttatcacaca actactggga
      121 attaaagacc ctcatatcac attctccaaa gaaatacacg acatgaaaac tcataaggaa
      181 ttgaaagctg tccttgacta cgatgcccca ccttgcccta actgccaaag tcagatgggc
      241 aagtacgact tccaacggga atccaaggtc ccttttctcg attgcgcagg ctacaagact
      301 ttgattcgcc tcaaaaagcg ccgtttcaaa tgtcagtttt gcggaaaaat tactgtcgct
      361 gagacttctc tagtccctaa aaaccatcaa ataccaacca tcgtcaaaca gaaggtggcc
      421 cagcttctca tcgagaaagt ctccatgacc gctatcgctg atagactatc catctccacc
      481 tcaaccgtca tgcgaaagct caacgagttc acgttcaagt ctcatttgac ttatttaccc
      541 gaacatatgt cctgggatga atatgccttt aagaagggca agatgagctt tattgctcag
      601 gactttgaca ccaacaacat catcgctatt ttggatggac ggacgaaagc tgtcattcgc
      661 aaccacttcc tgagatatcc tcggcaggtc agaaacgacg ttaaactcat caccatggat
      721 atgtttaccc cctattacaa cctggctaag atgcttttcc caaacgctta gattgtcctt
      781 gatcgtttcc acattgtgca acatttggga cgtgccatga accgtatccg tactcaaatc
      841 atgaactctt ttgatcgaaa atcccacgaa tacaaggctt tgaaacgtta ctggaagctg
      901 attcaacaag atagtagcaa acttagtgac aagcgttttt accgcccgac ttttcgcatg
      961 catttgacaa acaaggaggt ggtcgagcgt cttttgagct actctgacga gcttagaaag
     1021 cattatgacc tttatcagct tctgcttttt cacttccagg aaaagcaagc tgaccacttt
     1081 ttcggcctga ttgaggagca gatagacagt agcaatcctc tctttcagac cgttttcaag
     1141 acctttttga aagacagaga caagattgag aacgcactgg atttgcctta ttctaacgct
     1201 aaactggagg ctaccaataa tctcatcaaa gtcatcaagc gcaatgcttt tggatttcgg
     1261 aactttgaaa actttaaaag acggattt
//
LOCUS       DARYMD010000113         1286 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYMD010000113 DARYMD010000000
VERSION     DARYMD010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1286
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(233..727)
                     /locus_tag="TU818_001936"
                     /pseudo
     CDS             complement(233..727)
                     /locus_tag="TU818_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(953..1025)
                     /locus_tag="TU818_001937"
     tRNA            complement(953..1025)
                     /locus_tag="TU818_001937"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(990..992),aa:Lys,seq:ctt)
     gene            complement(1027..1220)
                     /gene="ssrS"
                     /locus_tag="TU818_001938"
     ncRNA           complement(1027..1220)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TU818_001938"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
BASE COUNT          377 a          226 c          224 g          459 t
ORIGIN      
        1 attgggaggt tgtgacaatc gagcggatat ccgatgttat ggcagaactt tctgagtctg
       61 aataatttta gttcaccaaa gaatcaagaa agaaccattg gggcaaaatt ggggcataag
      121 tttagaactt ttgtcgtttc ttgtgtcgat acaataccgg tttaatacta acaaatgctt
      181 ttattatcga ctttgtaacc attattgttc cttgtgtttt ttcgggaata aactcaagaa
      241 gtttttgagt tttttcttga atttcttttt catatttcaa tatgatgagt gaaattttat
      301 cttctttgga catagtgttg ttgtcttcaa gattaagttc tttagttgtt agagtgtttt
      361 tatctaattt attttgaaat attgcaaaat ctagaatttt ttgaagtaat acttcttcct
      421 cggccatacg gctataaagc caattatttt cgagtctctc taggtgctcc atccacttaa
      481 agtctctttt ttctcctaac atattgtagg gaaataaggt atcaatatca acatttaagg
      541 ctgtagcaat ctcttgaagc ctatcccatg aaggttcagt agtccccttt tcgtcattaa
      601 taattgtttg cttagtaact cctattaatt tagcgagttc tttttgtgtt tttccagctt
      661 ttaagcgagc atttttaata tctatttgtc caactgttaa agcctgcgaa taattaaaaa
      721 aagccatttt tctccaaatt ccgtcgcagg tgatggaggt gaaaatactc cgattgtatc
      781 accttgtgtt aattatatta ttgtcatgtg ttagctctct ttttaaaaag taataaattc
      841 tttatttaac atcatatcat aaaaaattgt ttcggggaca aatggtggga caaaccctct
      901 ttaggcaagc aaaaaagccc tgcaataaag gctttttgtc gtttttacac tataccccct
      961 acagggctcg aacctgtgac ccatagatta agagtctact gctctaccaa ctgagctaag
     1021 gaggtaagga aagctgtatt ggcaccggtg attcacgttt tgtattgaac ccgcacgata
     1081 taagcaggtg ggcaacatac ttctcttcag attgcttcca cgtgaaacgg cttgcatact
     1141 agagatagac tttgtttccc taaaatacaa aaaaatagtc ggtcaacact tagatgtgaa
     1201 ttcgtatgcc acagcaataa ctctatgctc ttatgatacc actttttgaa aatttttcaa
     1261 gccctaaaat gaaaaaaaga tcgtat
//
LOCUS       DARYMD010000114         1239 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYMD010000114 DARYMD010000000
VERSION     DARYMD010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1239
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..585
                     /locus_tag="TU818_001939"
     CDS             <1..585
                     /locus_tag="TU818_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL0924697.1"
                     /translation="SNKLKGKDLITIGIYTAIYFVINFAFMLAGMIPVMWIMMPSLIA
                     LFTGVPYMMICNKVQKAGAILIMGTVTVLIYYATGQFTTVILATFAVGCILAEIIRAI
                     TRYTSFIGNTLSFALFSIGMIGSPLPIWLFKESFFAHISEVGMSQDYINALEKFTSPA
                     ILIGVIILTFICSLVGALIAKRMMNKHFKKAGII"
     gene            587..>1239
                     /locus_tag="TU818_001940"
     CDS             587..>1239
                     /locus_tag="TU818_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL0924698.1"
                     /translation="MREYRLKIDPRAGISLLFILNFTIFNVSTVYALFVLLIWNCVYA
                     MCNGYCRIAIKFIFTYWLLYLIEFLVLPKLPSLIAISFAILLTYILKMLPVALFGYVF
                     VKTTSLYELITALRKIHFPESIITGLSITLRYFPALREDFHKTYDAMKLKNMSVLEKI
                     SGLIITTMTRATLNIEELSQAASVRGIDNPVKKFSAAEINFKTSDAVVFIVSSVVYI"
BASE COUNT          409 a          150 c          221 g          459 t
ORIGIN      
        1 agcaataagt taaaaggaaa agatttaata acaataggca tttatacagc aatttatttt
       61 gtaataaatt ttgcatttat gctagctgga atgataccag ttatgtggat tatgatgcct
      121 tcactgatag ctttatttac aggggtgcca tacatgatga tttgcaacaa agttcaaaaa
      181 gctggtgcta ttttaatcat gggaacagtt acagttttga tatattatgc aacaggacaa
      241 tttacaacag ttattcttgc aacttttgca gtaggttgta tattagctga aattattaga
      301 gcaattacta gatatacaag ttttataggg aatactttat catttgcact attttcaatt
      361 ggaatgatag gatcgcctct tcctatttgg ttgtttaaag aatcattttt tgctcatata
      421 tcagaggttg gtatgtcgca ggattacata aatgccttgg aaaagtttac ttcgccagcg
      481 attttgatag gagttattat tttgactttt atttgttcgt tagttggggc tttgattgcg
      541 aaaagaatga tgaataaaca ttttaaaaaa gcgggaatta tataaaatgc gtgaatatag
      601 attaaaaata gatccgagag cagggatttc cctgcttttt atcttaaact ttacgatatt
      661 taatgtatcc acagtttatg cattatttgt gctattaatt tggaactgtg tttatgcaat
      721 gtgtaatgga tattgtagga tagcaatcaa attcattttt acttattggt tgctttattt
      781 gatagaattt ttggttttac cgaaactacc aagtttaatt gctatttcct ttgctattct
      841 attaacttat attttaaaga tgttaccagt agcattgttt ggatatgttt ttgttaaaac
      901 tacaagtttg tatgagttaa ttacggcact tagaaaaatt cattttccag aaagtataat
      961 aacgggatta tcaataactc ttagatattt tccggcatta agagaagatt ttcataaaac
     1021 atatgatgct atgaaactaa aaaatatgtc tgttttagaa aaaataagtg gactgataat
     1081 tactacaatg acaagagcca cattaaatat agaagaatta tctcaggcag caagtgtaag
     1141 aggcatagat aatcctgtaa aaaaattttc tgcggctgaa ataaatttta agacaagtga
     1201 tgcggtagtg tttatagtgt cttctgttgt ctatatttt
//
LOCUS       DARYMD010000115         1211 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.116, whole genome shotgun sequence.
ACCESSION   DARYMD010000115 DARYMD010000000
VERSION     DARYMD010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1211
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            92..346
                     /locus_tag="TU818_001941"
     CDS             92..346
                     /locus_tag="TU818_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924699.1"
                     /translation="MIVTDKNYNDIADGVYKVDAGKVIRPWRNGKTFKTNGKDYRVLK
                     TEDNPDNGMQAIAVAPIKGSEVGKSHIMIVYVKSSYWLAS"
     gene            362..763
                     /locus_tag="TU818_001942"
     CDS             362..763
                     /locus_tag="TU818_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924700.1"
                     /translation="MMKKQQSKRRKLIGIVALITILGGILTMNWFNDEKLNRERREQE
                     RAAIYLSNTYENIHKIKIIGIDKNLKTGSMNIATIVNSKYYISVTFMGGEIYTGVEQA
                     SKDNEEFLNRRKKAENKTTLSKDIEVIYKEK"
     gene            766..>1211
                     /locus_tag="TU818_001943"
     CDS             766..>1211
                     /locus_tag="TU818_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924701.1"
                     /translation="MVSDKDYNKLSEKVYDVDANKVTISVRKNTDILNRYVKILKAED
                     TPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITA"
BASE COUNT          455 a          179 c          254 g          323 t
ORIGIN      
        1 agttggaatg ggaaattaag tttgatagac aaaaatccta taactcattt aagttcaata
       61 gataaaataa aagtaaaata ttggagtaac aatgatagta acagataaaa attataatga
      121 tatagccgat ggggtttata aggttgatgc tggcaaagtt attagacctt ggcgaaacgg
      181 taagactttt aaaactaacg ggaaagatta ccgcgtcctc aaaacagaag acaaccccga
      241 caatggtatg caggctattg ctgtagctcc gattaagggt agtgaggtgg gtaagagtca
      301 tatcatgatt gtttatgtaa aaagcagcta ttggctagcg tcctagcaat aaaaggagtt
      361 gatgatgaaa aagcaacaaa gcaaacgacg gaaactaatt ggcatagtgg ctttaataac
      421 aattttagga ggaatactaa caatgaattg gtttaatgac gaaaaactaa atagagagcg
      481 tagagaacaa gagagggcag ctatttattt aagtaataca tatgaaaata tacataaaat
      541 aaagatcatc ggtatagata aaaatttaaa aacaggttct atgaatatag ctacaattgt
      601 taatagtaag tactatatat ccgtaacgtt tatgggaggt gagatttata caggtgtaga
      661 gcaagcttca aaagacaatg aggaattttt aaatcgtcga aaaaaagcag agaataagac
      721 aaccttgagt aaggacattg aagttattta taaggagaaa tagtagtggt tagtgataaa
      781 gattataata aactctctga aaaagtatat gatgttgatg ctaataaagt aactatttct
      841 gttagaaaaa atacggatat tcttaatcgt tatgtcaaaa tcctcaaagc cgaagatacc
      901 cccgacaatg gtatgcaagc tatggctgtt gtaccaataa aagatggcaa agaggataga
      961 agtcatatcg tcattgccta tgccgggaca aatagcagtg atatacgcga tattgacacc
     1021 gatattcaat ccgttgtttt tggagatgat caatacctgt gtacccatga ggagcctgat
     1081 tcttttaaag tggtcaagag tcagctaagt actgctaaag ccttttccga ctacattagg
     1141 acaagctacc ctaacgctgc catctcctac accggacact ctctgggagg ctatctggca
     1201 ctcatcacag c
//
LOCUS       DARYMD010000116         1186 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYMD010000116 DARYMD010000000
VERSION     DARYMD010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1186
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..1131
                     /locus_tag="TU818_001944"
     CDS             <1..1131
                     /locus_tag="TU818_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL0924702.1"
                     /translation="AYFSLMFSAGTAIENTEELGFSHLIEHLLLRSGGEQSLNELFDN
                     NGAFIGGETSRDYINLMGYCKAENFKNIFEAIVSRVFNLNLTEEELLREKRVVLVELT
                     QYENGSKTEKLVSDNRLIFKNSKWSEDIIGVRENIESVDLKKLYKFYTENIQNGEFQI
                     AISGPNHLKEEIAIIENKLPVGRTPVKSNFPIFSSGVTERKKNQQVSEISMYIDISKM
                     TTSSHDVAILTILNAMLTGVKGSVLGGKLRTKNQWVYNIISFPIFYNGLTILKILTRT
                     PEIHKHQVVQVLKEDLVNREDLKNTKLFDKAKKRVINEVLMSYEVKKVEFLKTLCREK
                     LFNIPSWESVTGEIEKVSLNELNQFAKDALMQNKQFHIIINC"
BASE COUNT          452 a          136 c          216 g          382 t
ORIGIN      
        1 gcttattttt cattgatgtt ttctgcaggt actgccattg aaaatacaga agaacttggt
       61 ttttcacatt tgatagagca tttattatta cgatcaggcg gagaacaatc attaaatgaa
      121 ctatttgata ataatggtgc atttattgga ggtgaaactt ctagagatta tattaatttg
      181 atgggttact gtaaggctga aaatttcaaa aatatatttg aagcaatagt aagtagggta
      241 tttaatttaa atcttactga agaagaactg ctaagagaaa aaagggtagt tttagttgaa
      301 ctaacacagt acgagaatgg gagcaaaaca gaaaaattag tttcggataa ccgcctaatt
      361 tttaaaaata gtaagtggtc agaagatatt attggtgtta gggagaatat tgaatctgtt
      421 gatttgaaaa agctttataa gttttacact gagaatatcc aaaacggaga atttcaaatt
      481 gctatttcag gaccgaatca cttaaaagaa gaaatagcga ttattgaaaa taaattacca
      541 gttggaagaa ctcctgttaa atctaatttt cctatttttt ctagtggtgt aacagaacga
      601 aagaaaaatc aacaggtttc tgaaatttca atgtatattg atatttcaaa aatgacaaca
      661 tcatctcatg atgtagcgat attaacaatt ttaaatgcga tgttaacagg agttaagggt
      721 tcagtgttag gaggtaaatt aaggacgaaa aaccaatggg tatataatat aatttcattc
      781 ccaatctttt acaatgggct cactatccta aagatactga ctagaacgcc tgaaattcat
      841 aagcatcaag tagtacaagt tctaaaagaa gacttagtaa atagagaaga cttaaaaaat
      901 acgaaattat ttgataaagc taaaaaaaga gttatcaatg aagttcttat gagctatgaa
      961 gtgaagaaag tcgagttttt aaagacactt tgcagggaga aattatttaa tatacctagt
     1021 tgggagagtg ttactgggga aattgagaaa gtttctctca atgaacttaa tcaatttgct
     1081 aaagatgctc tcatgcaaaa caagcaattt catatcataa taaattgcta atatatttgt
     1141 taaagtgttc ttgataattt tgataaattg ttttatttaa agaatt
//
LOCUS       DARYMD010000117         1158 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYMD010000117 DARYMD010000000
VERSION     DARYMD010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1158
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..537
                     /locus_tag="TU818_001945"
     CDS             <1..537
                     /locus_tag="TU818_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0924703.1"
                     /translation="LNLSIRSGEILGIIGNNGVGKTTLLRCIAGLHKETKGEITLNGD
                     VISGKKRQRLSAMVMQDVNYQLFADSLVEECCLGNNCDNIQIDKVLGELKLIESKKSH
                     PMILSGGQKQRLVVANAILSDKKILIFDEPTSGLDYEGMLAVSNELKKLSEKNYYIFV
                     VSHDIEFINEICDRVYEF"
     gene            560..>1158
                     /locus_tag="TU818_001946"
     CDS             560..>1158
                     /locus_tag="TU818_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924704.1"
                     /translation="MSNKNWINTILDFASDCKGKLILSVVMASIGVFFSIIPYWSVYK
                     LMAVFIEQKATGEDVLYYGAIGIIAYFIRYICHGVSTILSHISAYTILRNIRENLGEK
                     LLSISMGNASKKTIGEYKSIIVDKVETIEMPLAHIIPECVAALLLSLGIAIFMVFISW
                     EMALAMFITVPFALMAYKKLMGNFNQLYEAQMKSNKYMNS"
BASE COUNT          427 a          127 c          229 g          375 t
ORIGIN      
        1 ttaaatctaa gcataagatc tggagaaata ttaggaatta taggaaataa cggtgttgga
       61 aagactacac ttcttcgatg tattgcagga ttacataaag aaacaaaagg agaaattaca
      121 ttaaatggtg atgttataag tggcaaaaaa agacaaaggc tatctgcaat ggttatgcaa
      181 gatgtgaatt atcagttatt tgcagatagc ttagtagaag aatgttgctt aggaaataac
      241 tgtgataata tacaaattga taaggttttg ggtgaactaa aattaattga gtcaaaaaaa
      301 tcacatccta tgatactttc cggtggacaa aaacaaaggt tagtagttgc aaatgcgatt
      361 ttatctgata agaaaatatt aatttttgat gaaccgacat caggattgga ttatgaaggt
      421 atgcttgcag tgtctaatga actaaagaag ttgagtgaaa aaaattacta tatttttgtg
      481 gtttcacacg atatagaatt tataaatgaa atatgtgata gagtttatga attttagata
      541 aaggaggtgg agaagttaca tgagcaacaa aaactggata aatactatat tagattttgc
      601 ttcagattgt aaaggaaagt tgattttatc agtagttatg gctagtatag gagtgttctt
      661 tagcattata ccttattggt cagtatataa acttatggca gtctttatag aacaaaaagc
      721 aactggagaa gatgtattgt attatggagc gattggtatt attgcatatt ttatcagata
      781 tatttgccat ggagtatcaa caatattatc tcatatatcc gcttacacaa tcttaagaaa
      841 tataagagaa aatttaggtg aaaaattgct cagtatttct atgggaaatg cgtcaaaaaa
      901 gacaatagga gaatataagt caattattgt agacaaagtt gaaacaattg agatgcctct
      961 agcacatatc ataccagagt gtgttgctgc attgctttta tcactaggta ttgcaatatt
     1021 tatggtcttc ataagttggg agatggctct tgcgatgttt attacagtgc cttttgcttt
     1081 gatggcatat aaaaaactaa tgggtaattt taatcagctt tatgaagctc aaatgaaatc
     1141 taacaagtat atgaattc
//
LOCUS       DARYMD010000118         1135 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.119, whole genome shotgun sequence.
ACCESSION   DARYMD010000118 DARYMD010000000
VERSION     DARYMD010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1135
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.119"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..1131)
                     /locus_tag="TU818_001947"
     CDS             complement(<1..1131)
                     /locus_tag="TU818_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924705.1"
                     /translation="MKEIVRSHRLLYVIVAFFSVISAFLMTLFSIQLGKILDSISNSS
                     SELLFQIVVCVCTIMAWFIMIWSYSYFKSYYVKKVILDLKERLFIGYLLREFNEIDTC
                     DRYNSDFLNNVTKNIDIIQENLLVPRVAVIVDLASMVTSVVAIVLIEWRLALVFLLLS
                     IVTVFLSQIPGKLMSKATRYYSEKSNHYLAEMTSFIEGFEQIKLLNIQKWIQKIEQNT
                     TLEFEDSRQKYQYRKDLASNTGMFLSFFSQVACMVAGIFFVRNNLLTVGLLVASIQLL
                     NGVFGPLQSFLYNKNLIKSTGTILTSIQEVLDKTNFVNGYIENKTFYEGDISSISINN
                     LTYQVENRKIFTNFSFEFKKGNTYAIIGPSGVGKTTLAKLILN"
BASE COUNT          418 a          197 c          124 g          396 t
ORIGIN      
        1 atttaatatc agttttgcta atgttgtttt cccaaccccc gaaggaccaa taatggcata
       61 agtatttccc tttttaaatt caaatgaaaa attagtaaat atttttctat tttcaacttg
      121 ataagttaaa ttatttatcg aaatgctgga gatgtctcct tcataaaaag tcttattttc
      181 tatataacca ttaacaaaat ttgttttatc tagaacttct tgaatacttg ttaaaatagt
      241 acctgtgctt ttgatcaaat ttttattgta aaggaaagac tgtagagggc caaacactcc
      301 atttaataac tgaatactgg ccactaatag tccaactgtt agtagattat tccttacaaa
      361 aaatatacca gcaaccatac aggctacttg agaaaagaag ctcaaaaaca ttcctgtatt
      421 tgaagctaaa tcttttctgt attgatattt ctgtctagaa tcttcaaatt ctaaagtagt
      481 attttgttcg attttttgta tccatttttg aatattcaat aatttaatct gttcaaatcc
      541 ctcaataaaa ctagtcattt ctgctaaata gtgattactt ttttcagaat aatatcgagt
      601 tgctttactc attaactttc caggaatttg agatagaaaa acagttacaa tagaaagcaa
      661 taaaaatact agggccaatc gccattctat aagtacaata gctactacac tcgtaaccat
      721 tgaagccaga tcaacaatca cagccactct aggaaccaat aaattctcct gaattatatc
      781 aatatttttt gttacattgt ttagaaaatc cgaattatat cgatcacaag tatcaatttc
      841 attaaattcc cgtaataaat aacctataaa aagcctctcc tttaaatcta aaatgacctt
      901 ttttacataa taactcttaa aataagaata ggaccatatc attataaacc atgccattat
      961 ggtacataca cacactacta tctgaaacaa taattcacta cttgaattag atatactatc
     1021 tagtattttt cccagttgaa tagaaaataa ggtcattaaa aatgcactga ttacactaaa
     1081 aaaagctact attacatata acaatctatg acttcttaca atttctttca taaat
//
LOCUS       DARYMD010000119         1027 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYMD010000119 DARYMD010000000
VERSION     DARYMD010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1027
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            145..1027
                     /locus_tag="TU818_001948"
                     /pseudo
     CDS             145..1027
                     /locus_tag="TU818_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSeq3 family transposase"
BASE COUNT          350 a          186 c          220 g          271 t
ORIGIN      
        1 gacataaaat ctaacaattg gggggctatt tttatgacat tgagttatga agacaaggtt
       61 caaatctatg agctacggca cattggaaag tccattaaat gcttatcaga aaagtttagt
      121 attgcagaat ctgacctcaa atacatgatt cgcctgattg acaggtatgg gttagccatt
      181 gtccaaaaag gtaagaatag ttattattct ccagaactga agcaagagat aatagataaa
      241 gttctgattg atggtcaatc tcaaaaacag acgtccttag actatgcttt accaaattct
      301 agtatgcttt caaggtggat agcgcaatac aagaaaaacg gctatactat tcttgagaaa
      361 agaagaggga ggccaccaaa gatgggacgt caaccaaaga agactttaga acaaatgaca
      421 gagttggagc gactccaaaa agaattagac taccttagag cggagaatgc tgtgctaaaa
      481 aagctgagag aataccggtt gagggacgaa gcaaagctca aagagcaaca gaaatcatcc
      541 aagaattaat cggtcaattt tctctagcaa ctttgcttga aatccttgat ttatcgcggt
      601 caacctatta ttatcaagtc aagcaactag ctcaagaaga taaggacatg gacttaaagg
      661 agctcattca aggcatctat gatgaacatc atggcaatta tggctatcgt cgcattcatc
      721 tggaactaag aaatcgtggt tttatcgtca atcacaaaaa agtacaacgt ttgatgactg
      781 tcatgggctt aaaagctcgt atccgtcgta agcgcaagta ttcttcttac aaaggtgagg
      841 ttggcaaaaa ggctgataat ctgattaaac gtcagtttga aggttctaag ccctacgaga
      901 agtgctatac cgatgtgacg gaatttacct tacctgaggg gaaactctat ctatcgcctg
      961 ttcttgacgg ctataacagt gagattattg atttcaccct gtctcgatcg cctgacttga
     1021 agcaagt
//
LOCUS       DARYMD010000120         1022 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.121, whole genome shotgun sequence.
ACCESSION   DARYMD010000120 DARYMD010000000
VERSION     DARYMD010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1022
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.121"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            50..1009
                     /locus_tag="TU818_001949"
     CDS             50..1009
                     /locus_tag="TU818_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0924706.1"
                     /translation="MKLEKGDIVKTALSENTTVLDVKDNQAVLFSGTQFVLATGIKEN
                     KESGKFEWDNGRYANDLKSISDIQNNNFETMKETLSFLAEYNHSDFVKGILSLETGIE
                     NEDTLDAAYDNYMNDKIMGLVDEKFYHYIDENEIEAPDLESEIQDKNSVLSDEENVKE
                     DNNTTSEKSNENKEKANTVNINGNIASDIDIKNLTSKDGRDFTVASFAVAENDKEGNV
                     KYTNCLAYNDKVSSVENLKKGDFVHVFGKEKISQGKDGKEYTSLKVYSAKLLKAKEQS
                     KTNQNAKDVKKPSALGKLKEYKEKAGEKSKEQVSVKKDKNIER"
BASE COUNT          446 a          105 c          214 g          257 t
ORIGIN      
        1 taaagaatta gaagaaaaca tacaagtaaa agtacaggag gtaaaaaata tgaaattaga
       61 aaaaggcgat attgtaaaaa cagcattaag tgaaaacaca acagttttgg atgtgaaaga
      121 taatcaggcg gtactgtttt caggtactca gtttgtactt gcaacaggga ttaaagaaaa
      181 caaggaaagc ggaaaatttg aatgggataa tgggcgatat gcaaatgatt taaaaagcat
      241 ttccgatata caaaacaata attttgaaac gatgaaagag accttatctt ttttagcaga
      301 gtataatcat agcgattttg tcaaaggaat tctgtctctt gaaacaggaa tagaaaatga
      361 ggatactctt gatgctgctt atgataatta tatgaatgat aaaattatgg gtttggttga
      421 tgaaaaattt tatcattata tagatgaaaa tgagattgaa gcacctgatt tagaaagcga
      481 aatacaggat aagaatagtg ttttatccga tgaggaaaat gtaaaggagg acaataatac
      541 tacgagtgag aagtcaaatg aaaataagga aaaagcaaat actgtaaata tcaatggcaa
      601 tattgcttca gatatagaca ttaaaaattt gacatcgaaa gatggtagag attttactgt
      661 tgcaagtttt gcagttgctg aaaatgacaa ggagggaaat gtaaaatata ccaactgttt
      721 agcctataac gataaggtaa gtagtgtaga aaatttgaaa aaaggagatt ttgttcatgt
      781 attcggaaaa gaaaaaatca gtcagggaaa ggacggaaag gaatatacat ctcttaaagt
      841 ttattctgca aagctgttaa aagccaaaga acagagcaaa acaaatcaaa atgcaaagga
      901 tgtaaagaaa ccgtcagcac ttggcaagtt aaaagagtat aaggaaaagg caggcgaaaa
      961 atcaaaggaa caggtcagtg tcaaaaaaga taaaaatata gagagataaa attataaaaa
     1021 ta
//
LOCUS       DARYMD010000121          908 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYMD010000121 DARYMD010000000
VERSION     DARYMD010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..908
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(7..492)
                     /locus_tag="TU818_001950"
     CDS             complement(7..492)
                     /locus_tag="TU818_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL0924707.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            complement(581..654)
                     /locus_tag="TU818_001951"
     tRNA            complement(581..654)
                     /locus_tag="TU818_001951"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(618..620),aa:Arg,seq:acg)
BASE COUNT          274 a          261 c          137 g          236 t
ORIGIN      
        1 ccccttttat ttctcaccag taaagtcctg aaagtaaggt cctatcttgc gaagcaaggc
       61 ccgtctcccc tcaaaccgct ctcccctgat caaagcccga aactgcgaca gctcaccctc
      121 tgtcaatcgc tcctcaacct ccttcacaat caactgataa gccacataat catctactcc
      181 caaaccacct gctggtatcg catggcctac cgacccaatc tcctcataag ccatcttatg
      241 aaaccgacgc ttctgactct cctgctgccg caacacgtcc ttcaaataag aggaaaactt
      301 ggtcttaaaa taacgatata gcttctcctc atcctctatc aattctggat aagtgaccaa
      361 taaccgatac aagatcaacc gcccctcctg taaccaatca tctagctccc acagctgaat
      421 ataataatgc tgtcttagct tcataataat aggcttgatc ttatcaaaca acctcactaa
      481 atcatcagtc attatacttt ctccttttca tgcttagtag ccttattata aggagacaaa
      541 caaaaaaaca acaggacaga aatgtcctgt tgccttgcta tgcaccctag aggagtcgaa
      601 cctctaaccg cctgattcgt agtcaggtac tctatccagt tgagctaagg gtgcttttct
      661 taactattac tatcctacca tactatcccc taaaaagcaa ggctctatac catctggaat
      721 aggtaagtcc actgtggaaa tcatagagct ttttgagtac acaaaaaaga gagcaccaaa
      781 ctgatcctct ctaaatgtcc gttgttagtc aacccactat agttgacata gagccaaact
      841 ccgccagtag gactcgaacc tacgacatca tgattaacag tcatgcgcta ctaccaactg
      901 agctatgg
//
LOCUS       DARYMD010000122          906 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.123, whole genome shotgun sequence.
ACCESSION   DARYMD010000122 DARYMD010000000
VERSION     DARYMD010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            45..464
                     /locus_tag="TU818_001952"
     CDS             45..464
                     /locus_tag="TU818_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924708.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGEELKKKKYR
                     QEQDRVVKYIGEHIELCNGQPITKIEFIEFQLETATTGTWSITTIVNEKYLIHFSEDR
                     LGEEIRTSYYSPKEFKQYSEKMRNNMTNVETIYYEEK"
     gene            461..>906
                     /locus_tag="TU818_001953"
     CDS             461..>906
                     /locus_tag="TU818_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924709.1"
                     /translation="MMIDRDYKNISEDVYKVDSGKERDPIQEGYPVANGKYRVLEAED
                     NPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITA"
BASE COUNT          333 a          151 c          189 g          233 t
ORIGIN      
        1 aaaaacttgc aacaccttat gataaagcat aaaggaatac aagcatgata gtctacctaa
       61 agcaacacaa aaattactgg aaattagtca gcatagccgc tttaatcatt attttaggag
      121 gaatactaac aatgaattgg cttaatggcg aagagctaaa aaagaaaaag tacagacaag
      181 agcaggatag ggtagtgaaa tacataggag agcatataga gctatgtaat ggtcagccta
      241 taacaaaaat tgagtttata gaatttcagt tagaaactgc aaccaccgga acttggtcaa
      301 taacaacaat tgttaatgag aaatatctga ttcatttttc agaagataga ttaggtgaag
      361 aaatacggac ttcctattat tctccaaaag aatttaagca atacagtgaa aagatgagga
      421 ataatatgac taatgttgaa acaatttatt acgaggagaa atgatgattg atagagatta
      481 taaaaatatt tcagaggatg tgtataaggt tgattctggt aaagaaagag atccgattca
      541 agaaggatat ccggttgcca atggaaaata ccgcgttctt gaagccgaag ataaccccga
      601 caatggtatg caggctatgg ctgttgtgcc aataaaagat ggcaaagagg atagaagtca
      661 tatcgtcatt gcctatgccg ggacaaatag cagtgatata cgcgatattg acaccgatat
      721 tcaatccgtt gtttttggag atgatcaata cctgtgtacc catgaggagc ctgattcttt
      781 taaagtagtc aagagtcagc taagtactgc taaagccttt tccgactaca ttaggacaag
      841 ctaccctaac gctgccatct cctataccgg acactctctg ggaggctatc tggcactcat
      901 cacagc
//
LOCUS       DARYMD010000123          906 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.124, whole genome shotgun sequence.
ACCESSION   DARYMD010000123 DARYMD010000000
VERSION     DARYMD010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.124"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            53..484
                     /locus_tag="TU818_001954"
     CDS             53..484
                     /locus_tag="TU818_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924710.1"
                     /translation="MVVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGDRDNKGENN
                     YYQVEKDLAMEIVSEFEGVKEISFLSPVQSKETGYWGTTATINKTNEISYSFSMTFSG
                     KLDDYSYYYDKCFKLVKRHKKLTLSQVDLTDIDIKYSKGGK"
     gene            485..775
                     /locus_tag="TU818_001955"
     CDS             485..775
                     /locus_tag="TU818_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924711.1"
                     /translation="MITDKNYNWLAGKVYDVDANKVTIPVRKNTDILNRYVKVLEAED
                     NPDNGMQFTVSKSNRNVLALNYKLRSFYDSKKESHHFIRNGSNFSNGRYIYV"
BASE COUNT          360 a          111 c          171 g          264 t
ORIGIN      
        1 taaaagcaaa aaacctgcac caccttatga taaagcataa aggaatataa gcatggtagt
       61 ctacctaaag caacacaaaa attactggaa attagtcagc atagcagctt taatcattat
      121 tttaggagga atactaacaa tgaattggct taatggggat agggacaata aaggcgagaa
      181 taactactat caagtagaga aggatttagc aatggaaatt gttagtgagt ttgaaggagt
      241 aaaagagatt agctttctta gtccagtaca atccaaagaa acagggtatt ggggaacaac
      301 agctactata aataaaacta atgagatatc ttattctttt tcgatgactt tttcaggaaa
      361 gcttgatgat tattcttact attacgataa atgttttaaa ttagtgaagc gtcacaaaaa
      421 attgacatta agtcaagtgg atctaacaga tattgatatt aaatattcta agggagggaa
      481 ataaatgata actgacaaaa actataactg gctagctgga aaagtatatg atgttgatgc
      541 taataaagta actattcctg ttagaaaaaa tacggatatt cttaatcgtt atgtcaaagt
      601 ccttgaagcc gaagacaatc ctgacaacgg tatgcagttt acggtgtcaa agagtaatag
      661 gaatgttcta gctttaaatt ataaactaag gagcttctat gacagtaaaa aagaaagtca
      721 tcattttatt aggaatggta gcaattttag taatgggagg tatatttatg tttagctata
      781 atcagaatca agcgaaaatg ttagaacgac aatttaacca tgaacaaaaa cgaattgtct
      841 tgtatttgtt aaatcattat agcggaatta atgagataga atttaatgat attgaaaaca
      901 acagta
//
LOCUS       DARYMD010000124          899 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYMD010000124 DARYMD010000000
VERSION     DARYMD010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..899
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(138..>899)
                     /locus_tag="TU818_001956"
     CDS             complement(138..>899)
                     /locus_tag="TU818_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0924712.1"
                     /translation="GKDMELSSHNIVFDKVRFAYDKIPIIKDVSFEIKENTVTAIIGP
                     SGSGKTTICNLISRFYDVSGGSIKIGNVNIKNLTLSSLLSNISTVFQKVYLFNDTIEN
                     NIKFGNPNVSKEEIINAAKKSHCHEFIMNLPNGYETIVGEGGDFLSGGEKQRISIARA
                     MLKDAPIIILDEATSSIDPENEYLIQRAISNLSKGKTVIIIAHRIVTIEEADQIIVLK
                     EGEIAQIGKHTELMSQDGLYRDYMRIRGKTEDWKI"
BASE COUNT          276 a          187 c           83 g          353 t
ORIGIN      
        1 taaaattcat atgacttctc gatacagcat aaatataatt atcttcccat ttagacactt
       61 tttccataaa aagcgaacct atattaccat tgcaacctaa aactcctata ttatacataa
      121 acctcctcct atctatatta tattttccag tcctctgttt tacccctgat tctcatataa
      181 tctctataca gaccatcttg gctcatcagt tctgtatgct ttcctatttg agcaatctct
      241 ccttctttca aaacaattat ctgatctgct tcttcaattg ttacaattct atgagcaata
      301 ataattacag tcttaccttt actcaaattc gatattgctc tttgaattaa atattcgttt
      361 tcaggatcta tgcttgatgt tgcttcatcc aaaataataa ttggagcatc ttttagcatt
      421 gcccttgcta tagatattct ttgtttttct ccaccagata aaaaatcacc accttcacca
      481 acaatagttt catatccatt tggcaaattc attataaatt catgacaatg tgacttcttc
      541 gctgcattta ttatttcttc cttacttaca ttcggattac caaattttat attgttttcg
      601 attgtatcat taaacaaata caccttttga aatactgtac ttatatttga aagtaaactt
      661 gataaagtca aattttttat atttacattt ccaattttta tactcccacc acttacatca
      721 taaaaacgag aaatgagatt acaaattgtt gttttacctg accctgatgg tcctataata
      781 gctgttaccg tattttcctt tatctcaaat gaaacatcct ttataattgg gattttatca
      841 tatgcaaatc ttactttgtc aaaaacaata ttatgactac tcaattccat gtcttttcc
//
LOCUS       DARYMD010000125          796 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYMD010000125 DARYMD010000000
VERSION     DARYMD010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TU818_001957"
     CDS             complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TU818_001957"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL0924713.1"
                     /translation="LPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKR
                     SIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFV
                     GNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAP
                     QGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILENQAPGAGNEVQLTD
                     AIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKHPQVKDDL"
BASE COUNT          188 a          210 c          198 g          200 t
ORIGIN      
        1 aggtcgtcct tgacctgagg gtgcttgaga gcatagtcaa gtgaggtctt cataaagcca
       61 aacttgtccc caacatcata ccgctctccc ttaaactccc tggcaaaaac ccgctgagtc
      121 ttgttgagct tgtcaatcgc atcggtcagc tgaacctcat tgccagcccc aggcgcctga
      181 ttctccaata tggcaaaaat ctcaggcgtc aacaaataac gtccaataat cgctaagtca
      241 ctaggtgcct catcaggact tggcttctca acaaaggtct ccacactata caagccctta
      301 acagccttcc cttgcggtgc aatcacgcca taattggaaa cctcctcatg cggaaccctc
      361 atcacagcaa tcgttgaggc gtgtgtacag tcataatcct cgataagctg cttggtcaag
      421 ggcttggcac taggattggt aatatccatg aggtcgtctc ctagcatgac cacaaagggc
      481 tcattgccca caaaggcctt ggcttggagg acagcgtccc ctagtcctct agggtggctc
      541 tgacgaatga agtgcaggtt gatggcagtg gtctcatcaa cgagcttgag cagctcggtt
      601 ttgcccttgg cttggagatt gtattcgagc tcgaagttgg agtcaaagtg gtcttcgata
      661 gagcgtttgg ccttgccggt gacgacaaga atctcctcga taccggcctt tagggcttcc
      721 tcgacgatga attgaatggt tggcttatcg acgattggga gcatttcctt ggccagtgcc
      781 ttagtggcag gcagga
//
LOCUS       DARYMD010000126          770 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.127, whole genome shotgun sequence.
ACCESSION   DARYMD010000126 DARYMD010000000
VERSION     DARYMD010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..770
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.127"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
BASE COUNT          221 a          118 c          140 g          291 t
ORIGIN      
        1 aaagaagttt gaaaccacat tagtgcctgc aaataaatct aaaaaaaact tcttcatcac
       61 cagttttatg tttgtctagc atggtcttaa tttctgtcaa caataatttt ttagaaccaa
      121 tatatctcat tctacatcct taatcatcct ttagttgttt cattatagca tattcatgtt
      181 gaagttccaa tattttattt gaaaaattat cttttgctgt atttctttat tgtagttttt
      241 aagcttagtt tatatgttgt tgattaaagg gaagaagaac ttaggttatc taaattgagg
      301 aattcgtctg taggtaacaa tgtattatgt ggccgagaga tttattttat atattaatga
      361 gatataagac ccctatcccg tccagcgtga cagacttgct atggaaaagc ttattttgag
      421 gctgtctgag gcttgcttat gtgtgacaag catttaggct agaacgctca ccttttttac
      481 tgcaagcaaa gctttagaag ctattgcaag atacttttag gcttgttact aagcgggtca
      541 tctctatcat ctcctagaga gtagtggagg ctatgacagt ttagcatata tggtttctct
      601 aatgatttga cgatgtaaaa ccataactac tgttattgta gggattatgt ataatatgta
      661 taaaaagaga agggcttgtt tctcagcgtt atcattttac ctataatgtc gctgccagtt
      721 tgcaaggctg ctgagattag tagctttttg gctatttttc tcatcttttg
//
LOCUS       DARYMD010000127          755 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.129, whole genome shotgun sequence.
ACCESSION   DARYMD010000127 DARYMD010000000
VERSION     DARYMD010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.129"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..>755)
                     /locus_tag="TU818_001958"
     CDS             complement(<1..>755)
                     /locus_tag="TU818_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HEL0924714.1"
                     /translation="FSNGGDSLIATKLSAKIEEKFKISFSIKDVMENITIEAQAQVIK
                     DRIAEQRFADKISVIEETITEEEFDLTDVQHAYYVGRNKDMILGGVSTHCYFEIESSD
                     IDVNKLEKAWNYLIKIHPMLRAIITENGKQKILQEVEYYKIMTSADSELIIRDIMSQQ
                     VLNLDKWPIFDIRISKREDKADIIHISFDNIILDGWSMFFILEQWSNIYKYGKYEEAI
                     NEISFREYVNYINKLKSTPKYFTDKEYWINRIE"
BASE COUNT          234 a          150 c           75 g          296 t
ORIGIN      
        1 ttctatacga tttatccaat attccttatc agtaaaatat tttggagtgc ttttcaattt
       61 attaatataa ttcacatatt ctctgaaaga aatttcatta atagcttctt catatttccc
      121 atatttgtat atattagacc attgttccag aatgaaaaac atactccatc catccaatat
      181 tatattatca aaactaatat gaattatatc cgctttatcc tcacgcttgc taattcttat
      241 gtcaaatata ggccatttat ccagattaag cacctgttgt gacataatgt cacggataat
      301 gagttctgaa tctgcactag tcattatttt ataatattct acctcttgca gtatcttctg
      361 cttaccattt tcagttataa ttgctcgtaa catcggatga atttttatta aataattcca
      421 cgctttctcc aacttattta catctatatc acttgattct atttcaaaat aacaatgagt
      481 agaaactcct cctaaaatca tatccttgtt tcttccaaca taataagcat gttgaacatc
      541 cgtcaaatca aactcttcct ctgtaatagt ttcctctatc acgctaattt tatccgcaaa
      601 acgctgctca gcaattctat ctttaatcac ttgggcttgt gcttcaatag taatattttc
      661 cattacatct tttatactaa aacttatttt gaatttttcc tctattttag ctgatagttt
      721 tgttgcaatt agagaatctc caccatttga aaaaa
//
LOCUS       DARYMD010000128          740 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.130, whole genome shotgun sequence.
ACCESSION   DARYMD010000128 DARYMD010000000
VERSION     DARYMD010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..740
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.130"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(220..705)
                     /locus_tag="TU818_001959"
     CDS             complement(220..705)
                     /locus_tag="TU818_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0924715.1"
                     /translation="MIGLVILFIALIILYLGVILFAGATFVKISLFALDKLVVFIASW
                     YYTHHYFSVKFSSGYAIYFWDILAAILVVIIYSILFQFIHKKFRVLGKILNLAISFFS
                     SMIVYCLLVNGFITTEKSYFLPLLNNSFMNQVVNYIIIAIISLVVWKRREDYLVETHD
                     K"
BASE COUNT          285 a          130 c           94 g          231 t
ORIGIN      
        1 aaaaaactac acttatggga gaatattcct ctcaaaactc tatgcttcgc aagctgcaac
       61 aagcaaagaa aaatacagat ttataccttg ataacagcct tgaaaaataa aaaaaagaag
      121 gagattatcc ctacccatat ttcaggtaag aataatctcc ttacttgctc tcaaattgat
      181 aaaagtatat tttctacaat atttcacaat aatattttct tatttgtcgt gtgtttctac
      241 aagatagtcc tctcttcttt tccacacaac caaagaaata atagcgatta taatataatt
      301 gaccacttga ttcataaagc tgttgtttaa aagtggcaga aaataggatt tttcagttgt
      361 aataaatcca ttcaccagga ggcaatatac aatcatagag ctaaaaaatg aaatagctaa
      421 atttaagatt ttccctaaca ctctaaattt tttgtgtatg aactgaaata gaatagaata
      481 tattattact accaatattg ctgccagaat atcccaaaaa tatatagcat atccggatga
      541 gaatttcact gaaaagtagt ggtgggtata gtaccagctt gctataaata ccacaagttt
      601 atccagtgca aacaggctaa tttttacaaa tgttgctcct gcaaatagaa tgactcccaa
      661 atatagtata attaaggcta taaaaagaat aaccaatcca atcatatcat tcacctctct
      721 atcaaaataa tcttcttttt
//
LOCUS       DARYMD010000129          737 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.131, whole genome shotgun sequence.
ACCESSION   DARYMD010000129 DARYMD010000000
VERSION     DARYMD010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..737
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.131"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            73..720
                     /locus_tag="TU818_001960"
     CDS             73..720
                     /locus_tag="TU818_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL0924716.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MIAQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGIFRLSRVHD
                     HFELIQYLEAHQLTINSEFRLIQIDDFAKTYTITYADKELIIPENIAKQLFVTAI"
BASE COUNT          249 a          136 c          151 g          201 t
ORIGIN      
        1 aggcctttgt caagattttt atgaaataat ctgatataat aatcattata aataagagaa
       61 aggcttttag acatgacgcc taataaagaa gactatttga aatgtattta tgaaatcgga
      121 gagcaaaaca ttaaaatttc taacaaaatg gttgcagaga gaatgaaggt ttctgcaccc
      181 gctgtgtcag aaatgattaa gaaaatgatc gcacaaggct ggattgtaaa ggataagacc
      241 tgcggctatt atctaacaga gcaagggcag cgcttagtgg caaatcttta tcgtaagcac
      301 cgattgatgg aggttttctt gatccatcaa ctgggctata ctgctagaga ggtgcaccaa
      361 gaggctgagg tactagagca tactgtgtca gatatgttta ttgatcgctt ggataaaacc
      421 cttggctatc ctactttttg ccctcatgga gggacaattc cacgccgcca gcagccacta
      481 atcgaaatca acaaaacaac gcttaatact attaaagagc tgggaatttt tcgtttgagc
      541 agggtgcatg atcactttga gcttatccag tacctagaag cacaccagct gacgatcaat
      601 agtgagttta gactgattca aatagatgac ttcgcaaaaa cctataccat cacttatgca
      661 gataaggaat tgatcattcc tgaaaacatc gccaagcagc tctttgttac tgctatttaa
      721 ataaaaaaag acctgat
//
LOCUS       DARYMD010000130          736 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.132, whole genome shotgun sequence.
ACCESSION   DARYMD010000130 DARYMD010000000
VERSION     DARYMD010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.132"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(2..712)
                     /gene="speh"
                     /locus_tag="TU818_001961"
     CDS             complement(2..712)
                     /gene="speh"
                     /locus_tag="TU818_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeH"
                     /protein_id="HEL0924717.1"
                     /translation="MRYNCRYSHIDKKIYSMIICLSFLLYSNVVQANSYNTTNRHNLE
                     SLYKHDSNLIEADSIKNSPDIVTSHMLKYSVKDKNLSVFFEKDWISQEFKDKEVDIYA
                     LSAQEACECPGKRYEAFGGITLTNSEKKEIKVPINVWDKSKQHPPMFITVNKPKVTAQ
                     EVDIKVRKLLIKKYDIYNNREQKYSKGTVTLDLNSGKDIVFDLYYFGNGDFNSMLKIY
                     SNNERIDSTQFHVDVSIS"
BASE COUNT          230 a          121 c           98 g          287 t
ORIGIN      
        1 attagctgat tgacacatct acatgaaatt gagttgagtc tattctctcg ttattggaat
       61 atatttttag catgctatta aagtctccat tgccaaaata atacaaatca aaaacaatat
      121 ctttacctga atttaaatct aaggtaacag ttcctttaga gtatttttgt tcccggttat
      181 tatagatatc gtatttctta atcaataact ttctaacttt tatatccact tcctgagcgg
      241 ttactttcgg tttattgact gtaataaaca taggcggatg ttgtttactt ttatcccaca
      301 cgtttatagg aactttaatt tctttttttt ctgaattagt taatgtaatt ccaccaaacg
      361 cttcatacct ttttcctgga cattcacaag cctcttgtgc agatagagca taaatatcta
      421 cttctttatc tttgaattcc tgtgatatcc aatctttctc aaaaaaaact gacaaatttt
      481 tatccttgac actatatttc aacatatggc ttgttacaat atctggagaa ttttttatac
      541 tatcggcttc aattaagtta gaatcatgct tataaagcga ttctagatta tgtctattgg
      601 ttgtattata agaatttgct tgaacaacat tggaatataa aagaaatgac aaacatataa
      661 tcatgctgta gattttctta tcaatatgtg agtagcgaca attatatctc attttttctc
      721 cttaagaagt gagagt
//
LOCUS       DARYMD010000131          672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.133, whole genome shotgun sequence.
ACCESSION   DARYMD010000131 DARYMD010000000
VERSION     DARYMD010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.133"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..>672)
                     /locus_tag="TU818_001962"
     CDS             complement(<1..>672)
                     /locus_tag="TU818_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL0924718.1"
                     /translation="AGKGTRMKSGLPKVLHKVSGLSMLEHVLNSVSALAPQKQLTVIG
                     HQAEQVRAVLGDQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGDTPLIRGESL
                     KALLDYHIREKNVATILTANAKDPFGYGRIIRNVAGEVVNIVEQKDANEAEQEVKEIN
                     TGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLKDFDESLGVN
                     DRLALA"
BASE COUNT          140 a          183 c          152 g          197 t
ORIGIN      
        1 gctagggcta ggcgatcatt aacccctagg ctctcatcaa aatccttcag caggtaagcg
       61 ccaacccttt cttggccagc cttgaaaata ctgatcacat cggttaggta gtactcccct
      121 tgggcattat cagtcgtgag atgctttaga gcctcaaaga ggcgcttatt gtcaaagata
      181 taagtccctg tgttgatctc cttgacctct tgctctgcct cattagcgtc cttttgctca
      241 acgatattga ccacctctcc tgctacattg cgaatgattc gtccatagcc aaagggatcc
      301 ttggcattgg ctgtgagaat ggttgccaca ttcttttctc tgatatgata gtctagcaga
      361 gccttgagac tttctcctct gatcaagggg gtgtcacctg caatcactag ggtttgtccc
      421 tctaagccag atagctcctc ttctgccatc atgactgcat ggcctgttcc tagctgctcc
      481 tcttgcacca ctgtcagtga ttgatcacct aggacggcac gtacctgctc tgcctgatga
      541 ccgatcactg tgagttgctt ttgaggagct agggctgaga cgctattgag gacatgctcc
      601 agcatgctta agcctgatac cttgtgcagc accttgggaa gccctgattt catgcgggtt
      661 ccctttccag ct
//
LOCUS       DARYMD010000132          633 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.134, whole genome shotgun sequence.
ACCESSION   DARYMD010000132 DARYMD010000000
VERSION     DARYMD010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..633
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.134"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(159..527)
                     /locus_tag="TU818_001963"
                     /pseudo
     CDS             complement(159..527)
                     /locus_tag="TU818_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017839.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          242 a          116 c           91 g          184 t
ORIGIN      
        1 tactatttcc tgaaaaagaa ataaacaaac gggcgtatga cgggttctgc attcctcctt
       61 cataggttaa taaaaattga agatgaaaga aagaaattaa aaaaaataat tccttaaaaa
      121 acacaaaaaa ccgccctcaa tcaagagagc ggttggtttt atttaaacac ataatgacta
      181 aaaagaatta caacaattag taatcccatt aaagagaaat agaaagaatg tctcatgaga
      241 aaatgacgcc atttatgctg gcacccatta tcacattttg acgaatagca gttaccaaaa
      301 tttttgcctg taattctagc tatccaaagc agtaaagaat acataagcgt caatatacca
      361 attaacatta agcttgcaat ggtaatcatt cttgataagt ccagagtctg aagatcacta
      421 ccaatgtcaa atatcgctct cgctacatct atgccaccaa acataacaaa aacaaaagct
      481 gaaaacacac ctaagatagc aataaagtct gtgtaaattg atgattttat ttcatcaaac
      541 ttaaacattt tttgttctat agcttttgtt ttgtctttga ggtcatgggc tcgctcttcc
      601 acctctgtag ttgttcgcaa aataaaattc ttt
//
LOCUS       DARYMD010000133          623 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.135, whole genome shotgun sequence.
ACCESSION   DARYMD010000133 DARYMD010000000
VERSION     DARYMD010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..623
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.135"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            185..>623
                     /locus_tag="TU818_001964"
     CDS             185..>623
                     /locus_tag="TU818_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0924719.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKGD"
BASE COUNT          245 a          112 c          150 g          116 t
ORIGIN      
        1 caatgtcaat aacatcaatc aaaaatcaga cgattaggat tttgattaaa aaaaaaaaaa
       61 acgaaaccaa agattgaaat tgatagatag ctattcccac tctaatagtg gacatgttag
      121 aatttccttt gggaaaggaa gttacaggaa actaagactg tttctaccac aaaaggagag
      181 aaagatgaga tacacattaa acaaaaacaa gcgtgctcgt aactacgggc tatgctcagc
      241 agctatcgct ctagcagcag tagccagcct aggaacagct ggcagcgcta aagctgagga
      301 agcaaaaaca ttagaccaac tacctaatcc agaagagcaa attctatata attattggga
      361 cacaaatgat cagaaagcaa gagaatatct tggagaccta tacggtttcc taaaatctta
      421 tttaggagag ttggaaaaaa aagctaaaga gcctggacct gctggaccta aaggtgaaaa
      481 aggcgaaaaa ggcgaaaaag gcgagaccgg tccgatgggg cctcaaggcc taaagggtga
      541 ggacggaaaa gacggcgcac ctggagaaaa aggagaaaaa ggtgatccgg gtatccaagg
      601 ccctaagggg gaaaagggtg acc
//
LOCUS       DARYMD010000134          598 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.137, whole genome shotgun sequence.
ACCESSION   DARYMD010000134 DARYMD010000000
VERSION     DARYMD010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..598
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.137"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(374..>598)
                     /locus_tag="TU818_001965"
     CDS             complement(374..>598)
                     /locus_tag="TU818_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0924720.1"
                     /translation="IQGQGEHGHKGHHGKDAKPSAPKADSKSTAKAMAPAAQKGTLPA
                     TGETNHPFFTLAALGVIASAGMLTLKGKKN"
BASE COUNT          163 a           98 c          131 g          206 t
ORIGIN      
        1 ttgaaaacat ttttatgata taataaagat attaacatta gaaaatgata tttgatgatc
       61 tagaaatagt atcataacta tcttgttaaa gaggttgaag aaattagcgc atagaaaaaa
      121 cgtatcagtt acgattatag tctagtttgt ctttatgaaa tatagataac actgtacaat
      181 ccttttcttt tattgtacga ctttatacaa agaaaagccc ttggaaatta ttttctaagg
      241 acttttttca atttgagagg ctggtgatag cctctttttg aacttaggtc atcttcttag
      301 ggcaatgctg cctgaagaga tgagaaaagc tgttactagc tcattgccta aggggaaagg
      361 tgcaatggct ggtttagttt ttcttgcctt ttaatgttag catgccggcg ctagcgataa
      421 caccaagggc tgcaagggtg aagaatgggt gatttgtctc ccctgtagct ggcagtgtgc
      481 ccttttgagc tgctggcgcc atagcttttg ctgttgattt agaatctgct ttaggtgctg
      541 atggcttagc atcttttcca tggtgaccct tatgtccatg ctcgccttgg ccttggat
//
LOCUS       DARYMD010000135          571 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.138, whole genome shotgun sequence.
ACCESSION   DARYMD010000135 DARYMD010000000
VERSION     DARYMD010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..571
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.138"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            97..387
                     /locus_tag="TU818_001966"
     CDS             97..387
                     /locus_tag="TU818_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924721.1"
                     /translation="MIDFVQIGTFCGAALSIFGVWGFIVNPFKKALEANELAMAQLKD
                     SIKELAYELKNLDRDGEITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            390..569
                     /locus_tag="TU818_001967"
     CDS             390..569
                     /locus_tag="TU818_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924722.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVASTVIM
                     SGIVCVLMNVSDIKE"
BASE COUNT          192 a           94 c          137 g          148 t
ORIGIN      
        1 tacgacaagc aaaccctcaa agatctggaa tcagaggata aagtcacagt tatcaagtac
       61 gctgatttgg ttaaaggcaa atagtgaggt gattagatga tagattttgt gcaaataggc
      121 actttttgtg gcgctgctct gtctatcttt ggtgtttggg gatttatcgt caatcctttt
      181 aaaaaagcgc tggaggctaa cgagctagcc atggcccaac tcaaagactc gatcaaggag
      241 ctagcctacg agctaaaaaa tcttgatcgt gatggagaga taaccaaaaa gattatcgat
      301 cggcatgagg agcgtttagg acgtgtagag gacgacatta ttgtcaataa agagcaaatc
      361 aaaacattat ttaaaaaagg agactaaaaa tggataaatg gtttaaaaaa gtagcaatca
      421 aaacaattaa gacaatggcc caaaccgctg taggggttat tggatcaagc gcattgatta
      481 ctgacgtcaa ctggcaggtg gtggcctcaa cagttattat gtcaggtatt gtctgcgtct
      541 tgatgaatgt gtctgacatc aaggaatagc a
//
LOCUS       DARYMD010000136          539 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.140, whole genome shotgun sequence.
ACCESSION   DARYMD010000136 DARYMD010000000
VERSION     DARYMD010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.140"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..>539)
                     /locus_tag="TU818_001968"
     CDS             complement(<1..>539)
                     /locus_tag="TU818_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0924723.1"
                     /translation="TVFNAPSSVNNLSKEAIDFVKANKGLYHSYRINNDYIGNLGTYL
                     GDDELGISRWVDGKAGIGRHSLAAYRFNSKGQVIDRKGHPAAAQAPALATLRSRLTDY
                     RRLKKQYAASNGISSSEEFYLDQFQSRAVAQALEQTTQLAQEEIIARRKEAVAEAEAL
                     HQKTRDMPFFVSELSWAEL"
BASE COUNT          130 a          138 c          127 g          144 t
ORIGIN      
        1 tctagctccg cccagctcaa ttcactcaca aaaaagggca tgtctcttgt cttttggtga
       61 agtgcctctg cctctgcaac cgcctccttc cgacgagcaa tgatctcctc ttgggcaagc
      121 tgagtggtct gctccaaagc ctgtgcgact gctcgagact gaaattgatc aaggtaaaac
      181 tcctctgagc tactaatacc gttagaagcg gcatactgtt tcttaagccg gcgataatcg
      241 gttagtctgg atcttagggt agcaagagca ggtgcttgag cagcggcagg gtgaccctta
      301 cggtcaatca cctgcccctt tgagttgaag cgataagcgg ctaagctatg acgtcctatt
      361 cccgccttac catcaaccca tcttgaaatc ccgagctcat catctccaag gtaagtgcct
      421 aggtttccaa tgtagtcatt gttaatgcgg tagctgtgat agagtccctt gttggcttta
      481 acaaagtcaa tagcctcctt ggagaggtta ttaacagagc ttggcgcatt aaagacagt
//
LOCUS       DARYMD010000137          513 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.141, whole genome shotgun sequence.
ACCESSION   DARYMD010000137 DARYMD010000000
VERSION     DARYMD010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.141"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..501
                     /locus_tag="TU818_001969"
     CDS             <1..501
                     /locus_tag="TU818_001969"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL0924724.1"
                     /translation="RYGLIEPREKVFVNAVPILIGPNGEQWQDFQKCYFDLPHWIEDL
                     QEKQILLSSYLSENYQVESLLKQSNGGNIYKAIHLDTGKNVVIKECRSHIICTASISK
                     KQLRDNEWNLSGLITNNIPKSIEKVHEWINDYYIYEYIDGQDLLDCCNEINLFSYKKR
                     ESEKNS"
BASE COUNT          205 a           58 c           88 g          162 t
ORIGIN      
        1 aggtatggac ttattgaacc tagagaaaaa gtttttgtaa atgcagttcc aatattaatt
       61 ggaccaaacg gagagcaatg gcaggatttc cagaagtgtt attttgattt acctcattgg
      121 attgaagatt tacaagaaaa acagatttta ttgtcgtcat atttaagtga aaattatcaa
      181 gtggaaagct tactaaagca atctaatggt ggaaatattt ataaagctat tcatctagat
      241 actggaaaaa atgtagttat caaagaatgt cgctctcata ttatctgtac agctagtatt
      301 agtaaaaaac agttgagaga taacgaatgg aatctatctg gtctaataac taataatatc
      361 ccaaaaagta ttgaaaaagt tcatgaatgg ataaacgatt actatatata tgaatatatt
      421 gatggtcaag atctactaga ttgctgtaat gagattaatt tgttctcata taaaaaaaga
      481 gaatctgaaa aaaattcata aagttcaata aat
//
LOCUS       DARYMD010000138          483 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.142, whole genome shotgun sequence.
ACCESSION   DARYMD010000138 DARYMD010000000
VERSION     DARYMD010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.142"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..>483)
                     /locus_tag="TU818_001970"
     CDS             complement(<1..>483)
                     /locus_tag="TU818_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL0924725.1"
                     /translation="LNQFGSSIYNIVFIIYVASTYHSKTLVSIANIILMIPILFQLLI
                     GQYADRIRNRAKWLIWGGISQSILFMIIAYLTNQKSYLVFSIICLINIISDCISNLLS
                     GISMPIFKHHIPQDELMTAYSLRNIISFICGIGGQIFGIWLLEISNKNFGFVAIINAF
                     "
BASE COUNT          200 a           67 c           64 g          152 t
ORIGIN      
        1 aaaaagcatt tattattgca acaaaaccaa agtttttatt tgaaatttca agtaaccaaa
       61 taccaaatat ctgtccacct atcccacaaa tgaaggaaat aatatttcga agcgagtaag
      121 cagtcattaa ttcatcttga gggatatggt gcttaaatat tggcatcgaa atcccagata
      181 atagattaga tatacaatca gaaataatat taataagaca aattatagaa aatactaagt
      241 atgatttctg attggttaaa taagcaatta tcataaataa tatggactga gagattcctc
      301 cccaaatcaa ccatttggct ctatttctta ttctatcagc atattgacct attaaaagtt
      361 gaaacaatat tgggatcatc aatataatat tagctatact tacaagagtt tttgaatgat
      421 atgtagatgc aacataaatg ataaaaacaa tattatatat tgaagagcca aattgattta
      481 aaa
//
LOCUS       DARYMD010000139          453 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.143, whole genome shotgun sequence.
ACCESSION   DARYMD010000139 DARYMD010000000
VERSION     DARYMD010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.143"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..>453)
                     /locus_tag="TU818_001971"
     CDS             complement(<1..>453)
                     /locus_tag="TU818_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEL0924726.1"
                     /translation="DQKIVRFKGFEDINDRDLRVGTFYYPKNEEKKHLILLVCGYEES
                     YLDFKSEIFFWLKNGYTVFCYDVRGTGRSQGRKVGGFTQFLKDCLLSIEYIEKNETFK
                     KVSLVGHSMGGFAVATSLQFKTNIIDNSVIISGFDYPSEFVRKSVTNIS"
BASE COUNT          152 a           95 c           43 g          163 t
ORIGIN      
        1 gaaatatttg ttacactttt tcttacaaat tcagatggat aatcaaatcc tgaaatgatt
       61 acactgttat ctattatatt ggttttgaat tgtaacgaag tcgctactgc aaaacctccc
      121 atactatgcc ccactaaaga taccttttta aaagtttcat ttttttcaat gtattcaatg
      181 gacaataagc aatccttcaa aaactgagta aaacctccaa cttttcttcc ctgacttctt
      241 ccagttcctc taacatcata gcaaaacaca gtatatccat ttttcagcca aaaaaatatc
      301 tcggatttaa agtctaaata ggattcttca tatccacaaa ctagtaatat caaatgtttc
      361 ttttcttcat tcttgggata ataaaatgtc cctactctca aatcacgatc attaatatct
      421 tcaaatccct taaatctaac tattttttga tct
//
LOCUS       DARYMD010000140          441 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.144, whole genome shotgun sequence.
ACCESSION   DARYMD010000140 DARYMD010000000
VERSION     DARYMD010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.144"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            9..>441
                     /locus_tag="TU818_001972"
     CDS             9..>441
                     /locus_tag="TU818_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="USG protein"
                     /protein_id="HEL0924727.1"
                     /translation="MFIIKGEVSRKDLIREIEKAIKSDELGAFIGAGLSIPAGFCSWK
                     ELLREPAEEIGLDVEKESDLVNLAQYYSNSKKRTSIDDLIKGQFSQLVKPTENHKLLS
                     QLPISTFWTTNYDKLIEKALENNMKKPYVKTKDEQLRGTNHN"
BASE COUNT          178 a           48 c           86 g          129 t
ORIGIN      
        1 gggaggaggt gtttattatt aaaggtgaag tatccagaaa agatttgatt agagaaattg
       61 aaaaagctat taaaagtgat gaattaggag catttattgg agcaggatta tcaattcctg
      121 ccggattttg tagttggaaa gaacttctaa gagaacctgc agaagaaatt ggattagatg
      181 ttgaaaaaga aagtgatttg gttaacttgg ctcagtatta ttctaattca aaaaagagaa
      241 catcaataga tgacttgatc aaaggtcaat tttctcaatt agtaaagcct actgaaaatc
      301 ataaattatt gtcgcagctg cccatttcaa ctttttggac aacaaattat gataagttaa
      361 tagaaaaagc tttagaaaat aatatgaaaa agccttatgt aaaaacaaag gatgaacaat
      421 taagaggtac aaatcataat t
//
LOCUS       DARYMD010000141          437 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.denovo.146, whole genome shotgun sequence.
ACCESSION   DARYMD010000141 DARYMD010000000
VERSION     DARYMD010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.denovo.146"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(68..139)
                     /locus_tag="TU818_001973"
     tRNA            complement(68..139)
                     /locus_tag="TU818_001973"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(104..106),aa:Arg,seq:ccg)
BASE COUNT          144 a           82 c           64 g          147 t
ORIGIN      
        1 attggtagat tttctgtcta acttttgggg tgcgggtcat ttaataggct tttttatatc
       61 gtttctatcc accttgaggg aatcgaaccc ccatctcaag aaccggaatc ttgcgtgata
      121 tccattacac taaaggtggc acctttaacc ataccactac agtatagcat aaaagtggat
      181 attttaaaat ccttttttct aaaaagatca caccatacac atgacgaaaa tgcatgtcat
      241 tattttctag tcatatgcat tttatcacta tatttttaat attttgacat catcagtggt
      301 tcaaatacag tttagttata ccataaatgt tcttgaaaaa acacattgat tacgaaaatg
      361 ctaccagaaa atgtcagttt ctccatgcat tggtatgcta aaaaaatact ataaaaagct
      421 gagcaattac ccagctt
//
LOCUS       DARYMD010000142        16864 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849018-rid18538163.guided.041, whole genome shotgun sequence.
ACCESSION   DARYMD010000142 DARYMD010000000
VERSION     DARYMD010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849018
            Sequence Read Archive: SRR25004155
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787500.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787500.1
            Genome Coverage       :: 141x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:02:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,986
            CDSs (total)                      :: 1,946
            Genes (coding)                    :: 1,862
            CDSs (with protein)               :: 1,862
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 31 of 84
            Pseudo Genes (incomplete)         :: 29 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 7 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16864
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849018-rid18538163.guided.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2021-04-06"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            215..595
                     /locus_tag="TU818_001974"
     CDS             215..595
                     /locus_tag="TU818_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL0924728.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            595..1443
                     /locus_tag="TU818_001975"
     CDS             595..1443
                     /locus_tag="TU818_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0924729.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            1543..2754
                     /locus_tag="TU818_001976"
     CDS             1543..2754
                     /locus_tag="TU818_001976"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL0924730.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            2747..4614
                     /locus_tag="TU818_001977"
                     /pseudo
     CDS             2747..4614
                     /locus_tag="TU818_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            4719..6464
                     /locus_tag="TU818_001978"
     CDS             4719..6464
                     /locus_tag="TU818_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924731.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISISKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            6464..8240
                     /locus_tag="TU818_001979"
                     /pseudo
     CDS             6464..8240
                     /locus_tag="TU818_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            8381..9730
                     /gene="gdhA"
                     /locus_tag="TU818_001980"
     CDS             8381..9730
                     /gene="gdhA"
                     /locus_tag="TU818_001980"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL0924732.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            9862..10272
                     /locus_tag="TU818_001981"
     CDS             9862..10272
                     /locus_tag="TU818_001981"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL0924733.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(10463..12469)
                     /locus_tag="TU818_001982"
     CDS             complement(10463..12469)
                     /locus_tag="TU818_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL0924734.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            12918..14639
                     /locus_tag="TU818_001983"
     CDS             12918..14639
                     /locus_tag="TU818_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0924735.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            14641..15804
                     /locus_tag="TU818_001984"
                     /pseudo
     CDS             14641..15804
                     /locus_tag="TU818_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            15956..16732
                     /locus_tag="TU818_001985"
     CDS             15956..16732
                     /locus_tag="TU818_001985"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL0924736.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            16725..>16864
                     /locus_tag="TU818_001986"
     CDS             16725..>16864
                     /locus_tag="TU818_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEL0924737.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FT"
BASE COUNT         4826 a         3062 c         3979 g         4997 t
ORIGIN      
        1 ctttcaataa ttattcgttc aactttttgg gggcagtaca ccttggggtg tttttttgtt
       61 gtaggagatt gattggttga tagaaggcag gtttatattt attgaagtga caaggtctgg
      121 aaaaaaatta tccaaaatac tggtttaagt ctactttaat attcgtcaaa tctatgctat
      181 aatgggtcat atcgccatta aggagaacga aatcatgcaa ttagtacgtg aaaaagaatt
      241 tgtcaatcag taccattatg acgccagaaa tttagaatgg gaaaaagaaa atggaacacc
      301 ggaaacaaac tttgaagtaa cctttcagtt gattaataaa gatgtggaaa ataaagagac
      361 ggctattgtt tctgttttac aatttgtcat tgtcaaggaa gagtttgtga ttagtggtgt
      421 gatttcacag atggttcgta ttttaggacg cttggtggat aagcctagtg aatttacaca
      481 agaggaggtc gaatccttgg ctgctccatt attagacatg gtgaagcgct tgacctacga
      541 agtgacagaa attgccttgg atcgtcctgg tattaatttg gagtttaaaa gttaatgaag
      601 ttagcaataa taactgataa tacagctcac cttccagagc agttagcgga gcatgccgat
      661 atttttgtat tagacatacc tgtaatcata gatggtcaaa gctatgtcga aggacaaaac
      721 ctgaccattg aagcctttta ccaaagcatg agagaatctc aagagctgcc aaaaaccagt
      781 cagcccagcc tctctgaatt agatgattta ctagggcgtc tgtcaactga gcactatact
      841 catgtgattg gcttgttctt ggctagtggt atttcaggat tttggcaaaa tattcaattt
      901 ctcatcgagg agcaccctga gttgaccatt gcttttccag atagtaaaat cacctcagca
      961 ccattaggca gcatggttag aaatgcttta gagtggtctc agcaaggctt gagctttgca
     1021 gagattatgg ataagctaga agagcaaatc gctggaacca cagcctttat catggttgat
     1081 gatttgaatc atttggtcaa gggaggacgc ttatcaaacg gttctgcttt gctgggaaat
     1141 ttgctcagca tcaagccaat tcttcgcttt gatagtgaag gaaagattgt cgtctatgaa
     1201 aaggttagaa cggaaaaaaa ggccatgaag cgcttggttg atatcttaaa ggaattgaca
     1261 gctagtggtc agtacgaggt atcaattatc catgctagag cgcaggataa ggctgatatc
     1321 ttaaagcagc tcttgttgga taatggctat acctgccctg ttgaggaggt tcattttggt
     1381 gcagtgattg cagcccatct tggagaagga gctgttgcct ttggcataac gcctcttgtc
     1441 taaagaggct tgcccatgac caatctgagc ttgatatgac agcctttaac gggaagcata
     1501 tgacaaggct ctaggagctt ttaggtggta gattaaaaca tgataacatt aatgacaatg
     1561 ccttctgaat ttcagaaggc tttaccaata gtgaaaaaaa tcaagcaggc tggctttgag
     1621 gcctattttg ttggtggaag tgtgagggat agcttattaa acaggcctat tcatgatgtt
     1681 gatatagctg ctagctgcta tccagaggag acaaaggcta ttttcttaag aacaattgat
     1741 gttgggattg agcatggcac agtgcttgtt ttagaaaatg gcagtgaata tgagatcaca
     1801 acgtttcgaa ctgaggacgt ttatgtggat tataggcgcc ctagtcaggt atcctttgtt
     1861 cggtccttgg aagaggattt aaaacgaagg gattttactg tcaatgctct tgccttagat
     1921 gaggacggac aggttattga tatctttaat ggcttagagg acctaaagca taagcttcta
     1981 agagctgttg gaaggcctca ggagcgcttt gaggaggatg ccctgcggat tatgcgaggc
     2041 tttcggtttg ctgccagctt agattttgat attgaggctg agacctttga agcaatgaaa
     2101 agccatgctc ccttgctgga gaagatttct attgagcgct cttttattga gcttgataag
     2161 cttttaatgg ccccaaaatg gcgtaaaggt atcttagcta tggtggcatg tcaggccttt
     2221 aactatttgc caggcttagt gggcaaggaa gaagccctgc aaaagtacct gaaaacctta
     2281 gcagcggatt atgtgtttca ggacaatcat caggcttggg cctatttgct ggttatgctg
     2341 gagcttgatc agcctaaagc ctttttaaag gcttggaaaa cctctaatga ttttcagcgt
     2401 agggttacga tgatggcctc tctttatcag attcgccaag aaagacagct agaaaaatgg
     2461 gatatttact cgtttggcaa ggacttggct ttactcgttg acgatttacg acaggcacag
     2521 ggcttggtca gtgaggccaa gcgtgttgag agcttgtatc aggagctgac gatccatgat
     2581 aagcatgata ttgtggtcaa tggctcttat ctgattcgtg agcttggaat gaagccagga
     2641 ccacagctgg gaatgctttt aaatcagatt gagcaggcca ttgtagaggg gcgtctcgtc
     2701 aatcaaagag aacacattga ggcttttgtt agaagggaac tactaaatga gtgattttat
     2761 cgttgaacat ctgacgaagt ctgttggaga taagaccgtt tttcaggata tttcctttat
     2821 tattcatgct ggtgatcgca ttggcattat tggtgtcaat gggacaggaa aaacaacctt
     2881 gcttgatgtt atttctgaaa aagtgggctt tgatggtgac cgctcacctt tttcaaaggc
     2941 aaatgactat cgtatatctt atttaacaca ggagccggac tttgatgatg atcagtctgt
     3001 tttagatact gttctgtccc tagaattaaa ggaaatgcag ctgattcgcc aatatgagct
     3061 gttgatggct gactattcag atagcaatca ggaaaagcta gcagaggtga tgactgagat
     3121 ggatcgatta gatgtttggt cgatcgaaag tgaggttaag acggtcttat caaagcttgg
     3181 tattgtcaat ctggatcaga gagtgggtga cctgtccggt ggtatgagac gtcgggtaca
     3241 gctggctcag gtcttgcttg gagccagtga tttgttgctg ctagatgagc cgaccaatca
     3301 tttggatatt gataccatcg cttggttaag tcattactta aggacctcta aaaggactgt
     3361 tctatttatt acacatgatc gctatttttt ggatagtata gccacacgta tctttgaatt
     3421 ggataaggct catgtgactg aatatcaggg caattaccag gattatgtgc gtctgaaggc
     3481 tgagcaagac gagcgcgaag cagctcattt gcataagaaa aagcagctct ataaacagga
     3541 gctggcttgg atgaggacac agccacaggc gcgtgcgacc aagcagcagg ccagaattaa
     3601 ccgctttgaa cagttaaaaa aggaccttca tcaggaaagg cctatagatc aattagatat
     3661 ggcctttgaa gccagtcgta ttggcaagaa ggtcattaat ttcaaggagg tttcctttgc
     3721 ttatggtgat caggccatta ttgagcattt taacctgatc attcaaaata aggaccgtat
     3781 cggcattgtt ggagctaacg gtgctggaaa gaccaccctg cttagcttga tgactggtga
     3841 cttaaaacca acagctggtc agctagagat tggcgagacg atccgtattg gttatttttc
     3901 acagcaaatc aaggatatgg acggcagcaa gcgcgtgatt agctatttgc aggaggtggc
     3961 agatgaggtc aagaccagtg ttggcaccac tagcatcagt gagcttttgg agcaatttct
     4021 ttttccgcgt tctagtcatg gctccttaat cgctaagcta tcaggcgggg agaaaaaaga
     4081 ctgtatttgc taaagctctt gatcgaaaag cccaacgtcc tgctgctgga tgagccgacc
     4141 aatgatttgg atattgcaac cttgacagtg ttggagcatt ttttagctca atttgctggt
     4201 ccggtcatta cagtgagtca tgatcggtat ttcttggata aggttgcaac aaaagtattg
     4261 gcttttgagc atggagctat cagagaatac tatggtaact atagcgacta tttagatgaa
     4321 aaggcttttg aagcagaggt catagagcct gctgtcagtg agcaaaaagc tggcactgac
     4381 catcaggtca cctctaaaaa gagaatgtcc tatcttgaga aaaaggaatg ggcagctatt
     4441 gaagaaaagc tagctgctat cgagcaacaa atagctacta ttgaggagca aatgctcaga
     4501 gcggcaagtg attacgacca attggcacaa tatcaaaagg agctggatca gcggaatctt
     4561 gagctgcttg aagcctatga gcgctttgat tacctaagcg aattagaaga ataattaatt
     4621 atgtgtcaat ttcatatttt tgtgttaaac tagttataga caaaaagaag tgctagcttg
     4681 cgcttctttt catatcacta ttatttggga ggaaatgaat ggctttaatt tggtcctatt
     4741 taaaaacaag acctaaatgg atttgtttcg atattgtggg tggcttgtta tttgttctgg
     4801 tcaatctggg gctaccaaca atattggctc gtatgattga tcaaggcgtt atgcagcagg
     4861 atcaaagggc tctttatttt tgggctctga tgatgtttat tatcgtactt ttaggtgtca
     4921 ttggacgggt gattttatcc tatgcttcgg gtaagctaac caccaacatg atcaaggatt
     4981 tacgtaatga catgtatagc tgcttgcagg attattcgca ttcggaatat gaaaaaattg
     5041 gcatagcctc cctggttact cggataacaa atgatgcctt tgttttgatg caatttgctg
     5101 aaatgtcctt gaggctgggt gtcgtaactc ctttgatgat gatcttttca gtggtgatga
     5161 tctttttaac cagtccatca ttggcttgga ttgtggctgt tgccatgcct tttttagtta
     5221 ttgtggtgct ttatgttgcg ataaagacaa gacccttatc agaaaagcag caggagagcc
     5281 ttgatcgtat taaccaattg gtgcgtgaaa acctgacagg tctgagagtt attcgagcct
     5341 ttgcaagaga agactttcaa gaagagcgct tcaataagcg caatgatcac tattctggaa
     5401 tctcaaagcg actatttacc ttgacaggct taacagagcc cttatttgtg caaattatca
     5461 ttgctatgat tgtggggatc gtctggtttg ccttggatcc cttggcaagg gggcagttta
     5521 agattggtga tttggtggcc tttatcgaat atagctttca tgctcttttt tcatttttaa
     5581 tgtttgccaa cctctttacc atgtacccta aaacagcagt gtcaagcaag cgtatcaagg
     5641 aagtgctgga tatgccgatt tcgatttcta aaaatgaaga tggtataaca gcgttcacaa
     5701 cacgtggtta tctagaattt gataacgtga cctttgccta tccgggtgaa acggaaagtc
     5761 cagttttaca taacatctca tttaagacta ggcctggaga gaccattgct tttatcggct
     5821 cgacaggttc aggaaaatca tctttggtta atctgatccc acgattttat gacgtgacct
     5881 tagggagaat cttggttgat ggcattgatg tcagggatta tcaattaaaa gcgctgcgtt
     5941 ctaaaatcgg ctttattcct caaaaagccc tgctatttac aggaaccatt gaggaaaacc
     6001 taaaatatgg taagtcagat gccagccaca gtgagcttga gcaggcaaca gaggtttccc
     6061 aagcgaagga ctttattacc agtcgtgaaa agggctatca aacccatcta gctgaggccg
     6121 gcagtaatct atcaggaggg caaaagcagc gcctgtctat tgccagagca gtggtcaagc
     6181 agccagacat ctatatcttt gacgattcct tttctgccct agattacaag acagatgctg
     6241 aattacgcag acggctgaaa gaggtgacac aagatgcaac ggtcttaatt gtggctcaaa
     6301 gggtgggcac gattatggat gctgatcaaa tcattgtctt ggatcaggga gaaattgttg
     6361 gccgaggtac acatgaggaa ttgcttacaa gcaatgccat ctatcgtgaa attgccaatt
     6421 ctcagctaaa caaggaagac atgacaaaag aggaggggga ttaatgactg aaaagcatgt
     6481 gtttagaaga atttggacct accttagtgc ctataggctc tcactaataa ctgccattat
     6541 tttaaaaata gtcagtgctg tgatgagtgt cttagagccc tttgttcttg gcttggtgat
     6601 aacagagcta tctgcaaacc tattagacat agcaaaggga gtctctggtg caggcattaa
     6661 taaaacctat atcgcctttc ttttagctct ctatatcatt agggcccttg tttacgagtt
     6721 aggctcttat ggttcaaact attttatgac aagggctgtg caatcaagca tttgtgatct
     6781 tcgtcgagac ctcagtcaaa aaattaatcg tatccctgtg tcttattttg ataagcatca
     6841 gttcggcgat atgctaggcc ggtttacctc tgatgttgag acagtctcta atgccttaca
     6901 gcagtccttt ttacagattg ttaacgcctt ttttaccctt attttggtgg ttggcatggt
     6961 cttgtatatt aatgcccccc tagcctctgt tgtgattatc gctatcccgt tgatatatgc
     7021 tgcttctcga tttgttttaa aaaaatcaca gccttatttt aaagcgcagg ctaatatttt
     7081 gggagaaatg aatggctttg tgcaggaaaa tttgaccggc tttaatattt taaaactgta
     7141 tggtcgtgaa gaagcctcaa aggaggaatt tcaccagatc actgagcgat tacaagaagt
     7201 aggctttaag gccagcttta tttctgggat catgatgcca gttctgcatt ttatttcaga
     7261 ttctgtttac atgattgttg ccttaatcgc tggcttacag gtgatagcag gccgcctgac
     7321 aatcgggaac aaacatgcaa gcctttgttc agtacatttg gcaaatcagt cagcctattc
     7381 agaccataac acagctggct ggtccactgc aaagtgccaa gtcatcctta gaacgtatct
     7441 ttgcagtgct tgatgaggca gatgaattga ctattgccca agagcattta gaacatgatt
     7501 taacaggtca ggtgtccttt aatcaggttg attttagcta tacagcagac aatcctctga
     7561 ttagaaattt caatttagag gttaagcctg gtgagatggt agctatcgtt ggtccgacag
     7621 gagccggcaa gaccaccctg attaatttat taatgcggtt ttatgatgtg aatgagggct
     7681 ctatcacagt tgatggtcag gacattcgtc agttgtcacg tcaagcctat aggcgtcagt
     7741 ttggtatggt gctgcaggac gcttggctct ttgagggcag cattcaggaa aacttgcgct
     7801 ttggtcattt agaggcgact gatgaacaaa taattgaggc tgctaaggct gccaatgttg
     7861 atcatttcat taggacattg ccaggtggct atcatatggt gatgaatcag gaatctagca
     7921 atatttccct ggggcaaaag cagctgctga ccattgctcg agctctctta gcagatccaa
     7981 agctgctaat cctagatgag gccacctcgt ctgttgatac acgtttagag cttttgattc
     8041 aaaaggcgat gaagcgatta atggttggca ggactagctt tgttattgct caccgcttat
     8101 caaccattca agaggcggat aagattttag ttctaaaaga tggtcagatt atcgagcagg
     8161 ggaatcatga cagcctatta gctgctaagg gcttctatta tgagctttat catagccaat
     8221 ttaagaccag tcagtcttaa aaagcttagg gtcttggaat gaatcgttcc aaggctcttt
     8281 taatttgctt tagatcatag taaaagcttg acatcaaaat tcagaaaatt tataatattg
     8341 actatactta aaatagaatg aagaagcgag aggatatata atggtatcag caaaagacta
     8401 tgtagccagt gtttttgata aggtcaaaag ggataatccg catgagactg aatttcttca
     8461 ggcggtcaag gaggtatttg attccttgat tcctgttttt gaaaaatacc ctaattatat
     8521 tgaggaaaat ctattagagc gcttggttga gcctgagcgt gtgatttcct ttagggtgcc
     8581 ttgggttgat gaccagggca gggtccaagt taatcgtggc taccgcgtgc aattttcatc
     8641 agctatcggt ccatataagg gagggcttcg ctttcaccct tctgttaacc agtctatagt
     8701 taaatttctt ggctttgagc agattttcaa aaatgctctg actggtcagc ctattggagg
     8761 aggaaaagga ggatcaaatt ttgatcctaa aggcaaatca gacctagaaa tcatgcgctt
     8821 cacacaaagc tttatgacag agctgcaaag gcatattgga cctgaccttg atgttcctgc
     8881 tggtgatatt ggtgtagggg ctcgcgaaat tggctattta tttgggcaat ataagcgtct
     8941 taatggcttt aagaatggtg tgttgacagg aaaaggctta gcttatggtg gctctttggc
     9001 tcgcacagag gccacaggct atggtgtggt ttattttgct cagcaaatgc tggcggctaa
     9061 ggggcaggac ttggctggta aaacagctat tgtatctgga tcaggaaatg ttgccattta
     9121 cgcaacggaa aaattgcagg ccttaggtgt taaggtatta gcagtgtcgg attcctctgg
     9181 ttacgtttat gatgataagg gcattgatct tgagacccta aagcaaatca aggaagtgaa
     9241 gcgtgagcgt atcaagacct atctagagag tcacccggct gctgtgttta caccggctgg
     9301 tgagggatcc atctggacta ttaaggcaga ccttgccttt ccatgtgcga ctcaaaatga
     9361 gctacaagag gcagatgcta aagccttgat tgagcatggg gttaaagctg ttgtcgaagg
     9421 ggctaacatg ccctcaacct tagaggctat tgagcaattt cagcaggctg gggttctttt
     9481 tggacctgct aaagcagcaa atgctggcgg tgtagcagtt tctgcgctgg aaatggcaca
     9541 aaatagcgga cgtaccgcat ggacctttga agaggtggat catcgattgt atgacatcat
     9601 gaaggctatt tatcaaaaag cagccgctgc cgccaaggaa tgtggtcaag aaggcaacct
     9661 agtggtggga gctaatattg caggctttct caaagttgct caggccatgt cagcacaggg
     9721 aatcgtttaa gagctgtggc tggtatatgc tgaatatatc agtagggtta gcacattaat
     9781 cttagctcaa tgacgttaag atatacgatc ggtcatctag acaatgcatg ccgattagag
     9841 caatgaatca aggagaagct gatgatcaaa aaaatcgtga aggacacctt tttcttgcag
     9901 caaaaagcac agccagcaac gaaaaaggac ctttggattg gtcaagacct gcaggatacc
     9961 ttagcttatt atcgtgatag ctgcctgggg ctggctgcta atatgatagg ggaaaacaag
    10021 agggttatta ttattagcat gggctttgtg gatttggtga tgtttaatcc tgtattaatt
    10081 gctaagcgtg aagcgtttga ggcagaggaa tcctgcctat cactaatcgg ccaacgtaag
    10141 acaaagcgtt atcaggagat caaggttgat taccttgatg cacattggca caagaaatcc
    10201 ctgagattga caggcctgcc tgcacaaatc tgccagcatg agctggatca tctggagggc
    10261 atattgattt aaatcatgac cacccgttag tgaactgcac cccaaaagtt agacagaaaa
    10321 tctaacgaat gagggcagtc catagatggg tggtttattt gtcttgctca acaggtgcga
    10381 aacaaataaa cgtcacataa atcagaaaac cggctgtatg cttaagatac agtcggttat
    10441 tgctgttatg gctaggacga ttttattggc cttccttttt cttgaaaagg ctagtaccag
    10501 ttaaggttag tagtcctagg attgtcatgg cagcagcaga atgctggctt gttcctgttg
    10561 ctggtaaggc agcattagct tgctttttag ctgctagagg cttgatgctt gtggcaggat
    10621 tagcattttg agcaggcgta aataggtcag agacaagctc agtagcaagc accttgccct
    10681 cacgattctt aaagacgcgg ttgatgatct cgtgcttgcc ggtatgatca ctttgagtag
    10741 agccttcaag actggcagtg acataggttt tcacaccgtt aataccagca cttacagtct
    10801 ttccagctgc ttcaaggtcc ttgatgtatt cgataaagac ctcagtatca ggattaatgg
    10861 ctcctagtag cttagcgtcc ttaaagacgg agaagccatc accaccgcca tataggaagt
    10921 cgttgatgat tagggtgtat tgagctgctg gatcaatttc ttcaccatta tctttataag
    10981 cctttactac cttaaacggt gttgaaggat cgttagcctc attagctgta taagtgtatt
    11041 tgagtccaga catttgaagg aagtattttt ggtcttcatc gtattgttgg ttcaagacat
    11101 catagatttg ttggccagtc atttgaacga cctgaagaat attgccaaat ggttgaacag
    11161 cctgtgcagc tccccaggta atggtttgat cctctttgac caccaagtca gcgcgaatac
    11221 cgccattatt tgtcatggca aaatcaacat gagggaaggt ttttctacca atggttaatt
    11281 gggcagttgt tatcaaattg ccaacaggag attccttgtc ttcgttttct gttttagaaa
    11341 tcgttgaaga ggtagctgct gtaccgatct ttagctcggt aacggttttg acaatgtcat
    11401 tggcttgatc aacaatggct tgaatgtcgg cattgcctgt ttttatgcca ggagcaacgg
    11461 caatgacctt tgcttcagga gtggctacaa aatcattgag gtcagtgtct agtgttccac
    11521 gaacatctgc ataggctttc ccctgtgaaa cagcctgaac gacacgtgtt gtgccaatgg
    11581 taccgttggt gtattggtgg ttgtgaccag caaagacaat atccacacta tgctcaggat
    11641 aaagctggtt aaccttttcc ataactgctg ccatctcatc atgaactacc ccgttatcac
    11701 ttgttgctgg gatatgagct aggacaacaa tcgcattgac ctgctgctct tggagctctt
    11761 tagcatattt aacgatggtt tctgcagagt ctaggtaatc atattgttca taattttgtt
    11821 ttaggacaag gtttggaatt tctgttgtca caacaccgat aaagcccacc ttgactgact
    11881 tatcattaac tgggacttct ttgacagcat aaggcttcca gccaaaagga atcgtgttgg
    11941 tctccttgtc aacgacattt gcaatgacaa gggtttgatt tgaagcttca tgctcgtatt
    12001 gcttagtaat gtcgttgata gctgagtctt cagcaggtgc agtgcctgtc atgatacggt
    12061 tgaattcagc taagccctca tcgaattcgt gattcccaag ggttccgtat tcaaagccca
    12121 tctggttgaa taccttaacc gttggctcgt cctgtaatag tccagaatta gcaggactag
    12181 ctccgaccat atctcctggt tgaacacgaa tgcttgtccc atctgggctt gtttgcttaa
    12241 agtcagcctc tgcatcgtcc agataagcag ctaattgtgc tgcggtacca gcgttagata
    12301 cctttccttc tggcatgtag gcagagccgg ttgtgtctaa ggcaccatga aagtcattga
    12361 caccaagaaa ttgcacgtct acctgatcgg cctgcacgcc ggttactagc atagaaactc
    12421 cggcaaagac accaagaaca ctacttttta aaacaaaatg ctttttcata aacgctccta
    12481 aaagtttaaa gtattgtcac aagttaagtg tactattatt taaatgagaa ttcaacaaaa
    12541 attaataaaa aagctaacaa aaattcaacg atagcgtttg ctaatcactg aaaacgttta
    12601 aaatgcaaac attggaagcg ttttttgtaa aaaaatagaa gaactatcca aaaaaggctt
    12661 tacaagccca gtattctatg ataagatgtt aggcagatta aaagaaagga gaaattaata
    12721 atgatccgtt tcattcaact atttaaccat tattacgata gtctcctttc taaccaaaac
    12781 agttagtttc ttttagtttc actaaataga aatagtagag cccgcggtag gaaggatatc
    12841 ttattgcggg ctttttgtgt gcaaaaatcc tattttaaga cagcttgaaa taggttagtt
    12901 cagaaatgga ggatatgatg ctgaccttaa ttgttcaaca tattaagcaa aagaaatgga
    12961 tttatatcct tattgcaatg actttagtga tatatgatgc ctcacttgtg ataccaacaa
    13021 gggttattca agacttggtt gatttgatgt caaggcatca gctaagctca ggggcattgg
    13081 tgaggcatgt tatcattctt ttggctacgg cagtagtgtc ttatggggtt gcttatttgt
    13141 ggcatcttca tttatttcag gaggcagttc attttaagtt tgatattcag cagcgtgcct
    13201 ttcgaaagct tgtttttatg agaacgcctt tttatgagaa atttcgctca ggtgacatga
    13261 tcacgcgttt ttcaacagat gtcgaagcac ttatggacct tatcggctat ggcttgatga
    13321 ttatcctata tgctggtggt atgattgctt ttattattcc gaccatgttt ttgatttctt
    13381 ggaaaatgac cttgatagga atagtaccga ttttgcttat gatggtgatg atctatggtg
    13441 tgacgaaaaa gcaagagcat ttggttgaag aggcgcgtga ggcgatttca agccttagtg
    13501 atgaggtact agaaaccgtt gagggcatta gagtgatgcg tgcttacagt aaaaaagatt
    13561 atttggcact tcattttgct caaaagactc agaatttggc agataaatgg aatcaggtgg
    13621 ccaagtatcg tgccttgtac tttcctcttt acagcgtcat gattgccatt agtacagtaa
    13681 tcattttaat ggtaggccta cagctcatag caagctcaga ggtaacactt ggtcaagtca
    13741 ttgcgctgca gctttatctg gtgtctttgg tggagccctt tggcatgctg tcagacttta
    13801 ttttggttta tcagacagga aagacctctt ttggtaagat taatgaactc atcgaaacaa
    13861 gtgatgatat ggagcctgat ggccagcttg agttagagag ctttgatcag attgctttta
    13921 tagactatag ctttacctat gccaatagtt ctaggcctag cttagaaaag atcaatttaa
    13981 ccctgaaaaa gggacaaacc ttagggattg ttggtaaaac aggctctggt aaaacaaccc
    14041 ttgtcaggca gtttttgaga caataccctc ttgggcaggg gcagctgatg attaatcatc
    14101 gtagtgtctt ggattataag cgtcaatcac ttgagcgtca aattggctat gtgccacagg
    14161 agcatatcct gttttcaaaa acggttgctc aaaacattgc gatggggaaa aaggcagcta
    14221 caactgagga aatcttggag gcgattgaaa ctgcggcctt tacgcgtgat gttcaaggaa
    14281 tggcaaaggg cttggatact gagattggag agcgtggtct gtctatttca ggaggtcaaa
    14341 agcagcgtat ttcgattgcc agagcctttt tgtcccagcc agatttgctg attttagatg
    14401 attccctgtc ggcagttgat gctagaacag agactgatat tattcgacac attcaagacg
    14461 aaagaaaggg aaagacaaca cttattgtta gccatcgctt gtctgcgatt cagcatgccg
    14521 attgggttat tgttctggat caggggcaga tagtagagga aggtcagccc caacaacttt
    14581 tagctcagaa gggctggtat tatgaacagt accagcgtca gcaggctcag gaggtttaag
    14641 atgaccctat ttataaaatt aataaaagaa attaaagctg tgaccttggc tttttccctg
    14701 gcaataggct ttttgctagt ggcaacagct ggaggtcaga tggctccctt attgttgcaa
    14761 caaacgattg atcattactt gactccgata gctagaggaa aagaggtacc gattgaaggc
    14821 tttcagcgct tgctcctgct gtatttgctg ttaattgtga taacagcagt tttgcgttat
    14881 atctcttatc gaatgctggt ttattcctct aataggatcg ttgctaatct tcgtaatcga
    14941 gcctttgatg tcatgcagag gctgccgata gcttattttg atcatcagcc tgcaggaaag
    15001 attgcaacta ggattgttaa tgatactgaa accctgaaga atcaatttta tgataacctt
    15061 ttgtctcaaa ttattgtcag tctttcacaa attattttta tttatgtggt gatgatttac
    15121 cttgatgtga agtcaggctt gctgttgctg cttattatgc cactctttta tggcatgcaa
    15181 tggctgtata aaagcttgac tgaccagcca atgaaggatt tttatcaggc taggagcgct
    15241 gtcaacacac aagtcaacga aaccatgaat ggtgtttcta ttattcagct ttatcatcaa
    15301 gaggatacga tcttagagga atttgaagag cagatccacc agatgaaaac agctgatgat
    15361 aggattattt ttgcagagtc agttgcttca tggaccctga cggaattggt aaagtatggc
    15421 atgattgccg ctattttggc tgttattggt taccagttct tgcaggggag atcaggcatc
    15481 acagttggta agctctttat ttacgtcaat tatttgctgc gcttgtttga tttattaagt
    15541 atgctggtta ggcagctacc taatattcag cgctcaacag cgacaggaac gcgcctaatg
    15601 aagctgcttg aggcgcagac agagccggat aaagcacgag caattgagct aacagatggt
    15661 actgtggatt ttaccaaggt gtattttgct tacgaaaatg gcaagacagt tttatctgat
    15721 attaccattc atgctgataa aggggagacg gttgccctag tagggcatac tggctctggg
    15781 gacaatgcta taatgatgat agtacaataa atccaagtaa aatcaatggt taaaggcttc
    15841 cgcaaaactt ttaaacttga tgatggattg aggctatcat ctttttttat atctaaaatt
    15901 atataaaagt atagcataaa atgaaatctc tgtatagaga agaaggaggg actttatggc
    15961 agaagtgata accatagcca atcgaaaagg cggagttgga aaaacaacta caactctaaa
    16021 ccttgcctat tcactaaaag aactggggaa aaaagtatta gtcattgacc ttgatccaca
    16081 agctaatctt acaagatgtt ttgatatggg aaatacagaa aatataaaaa ccatagggca
    16141 tttgttaatg gtagaactgg aggaagaaga aagctatttg gtagagggct ataccaaatc
    16201 ttatgatgag atagatatta tcccctcaag cattttctta tccgccgttg aaacacaaat
    16261 gagagcagaa acaggaagtg aacgtatatt atcggaaatt attaggaggg taaaagagaa
    16321 ttatgactat attctcatag atacatcacc atcacttagt gttttgacta taaatgctct
    16381 ttgtgcctca gacagtgtcc ttatagtagc ggatacacag ctgttcgcag ttgttggaat
    16441 caatgaactt ttaaaaactg ttcaaaaaat aaaaaagaga gtgaatccga aactgaaagt
    16501 gcaggggatt ttactaacca tgtgtgagaa tagaaccaat ctgtccaaaa cactgatgga
    16561 gcaagtagaa gaaatgttcc aaaagaaaat caaggtcttt caaaccaaaa ttccgaaaac
    16621 agttaaagtt ggggaagcca tctatagcgg gcaaagcata aaaaaatatg caaaaggcag
    16681 tagtgtagac attgcctatg acaatctggc aaaggagatc tgctatgagt aaaaaacttc
    16741 taaagagaga aatcaccgat gccgtagatt ttttgcttga tgatggaaat gccttggaac
    16801 aaggaaatat acagaatata gaacttgatt tgcttgaaaa ttatcataat catccgttta
    16861 cttt
//
